105
10
1
1914
1
Cat. No. | Product Name | ||
---|---|---|---|
L9840 | 抗阿尔茨海默症化合物库 | 986 compounds | |
986 种阿尔茨海默症相关的化合物集合,可用于高通量和高内涵筛选; |
Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T11634 |
IL-15-IN-1
|
IL Receptor; Interleukin | Immunology/Inflammation |
IL-15-IN-1是一种 IL-15依赖性细胞的选择性抑制剂(IC50:0.8 μM)。 | |||
T14367 |
AZ1495
|
IRAK; CDK; Haspin Kinase | Cell Cycle/Checkpoint; Immunology/Inflammation; NF-κB |
AZ1495 是一种口服有活性的白介素-1受体相关激酶 4(IRAK4)抑制剂,能够作用于 IRAK4 (IC50:5 nM)和 IRAK1 (IC50:23 nM)。可用于研究突变型 MYD88L265P 弥漫性 B 细胞淋巴瘤 (DLBCL) 。 | |||
T9448 |
IL-17A inhibitor 1
LY3509754 |
IL Receptor | Immunology/Inflammation |
IL-17A inhibitor 1 是 IL-17A 的抑制剂,在alphalisa assay 中的IC50为 <9.45 nM。IL-17A inhibitor 1抑制HT-29 细胞的 IC50 值为 9.3 nM。 | |||
T4140 |
IRAK4-IN-1
|
IRAK | Immunology/Inflammation; NF-κB |
IRAK4-IN-1 是白细胞介素-1 受体相关激酶 4 抑制剂(IC50:7 nM)。 | |||
T5094 |
IRAK inhibitor 1
|
IRAK; JNK | Immunology/Inflammation; MAPK; NF-κB |
IRAK inhibitor 1 是IRAK-4抑制剂(IC50:216 nM),微弱抑制 JNK-1 (IC50:3.801 μM)和 JNK-2(IC50>10 μM)。 | |||
T9631 |
IRAK-4 protein kinase inhibitor 2
|
IRAK | Immunology/Inflammation; NF-κB |
IRAK-4 protein kinase inhibitor 2 是有效的白介素 1 受体相关激酶 4 抑制剂,IC50为 4 μM。它在与炎症和免疫相关的疾病领域有研究价值。 | |||
T60012 |
HS-243
|
IRAK; MAPK; CDK | Cell Cycle/Checkpoint; Immunology/Inflammation; MAPK; NF-κB |
HS-243 是 IRAK-4 和 IRAK-1 的抑制剂,IC50 分别为 20 和 24 nM。 HS-243 显示出抗炎和抗癌活性。 | |||
T7649 |
Tyrphostin A1
AG9,(4-甲氧基苄烯)丙二腈,Tyrphostin 1 |
EGFR; Interleukin | Angiogenesis; Immunology/Inflammation; JAK/STAT signaling; Tyrosine Kinase/Adaptors |
Tyrphostin A1 (Tyrphostin 1) 对巨噬细胞培养中CD40L 刺激的IL-12产生和抗原诱导的Th1细胞生成具有抑制作用。 | |||
T2457 |
IRAK-1-4 Inhibitor I
IRAK-1/4 Inhibitor I,IRAK-1/4 Inhibitor |
IRAK | Immunology/Inflammation; NF-κB |
IRAK-1-4 Inhibitor I 是一种IRAK1/4双重抑制剂,其IC50分别为 0.2 μM 和 0.3 μM。 | |||
T5110 |
IRAK inhibitor 6
|
IRAK | Immunology/Inflammation; NF-κB |
IRAK inhibitor 6 是白细胞介素-1受体相关激酶-4的抑制剂(IC50:160 nM)。 | |||
TQ0167 |
Zimlovisertib
PF-06650833,PF06650833 |
IRAK | Immunology/Inflammation; NF-κB |
Zimlovisertib (PF-06650833) 是口服有活性的、可生物利用的白介素-1 受体相关激酶 4 (IRAK4) 选择性抑制剂,其IC50=0.2 nM,在 PBMC 分析中,IC50=2.4 nM。它具有研究类淋巴瘤、风湿性关节炎、狼疮等疾病的潜力。 | |||
T11673 |
IRAK4-IN-4
|
IRAK; cGAS | Immunology/Inflammation; NF-κB |
IRAK4-IN-4 (化合物 15) 是白介素-1 受体相关激酶抑制剂,IC50为 2.8 nM。它还抑制环 GMP-AM 合酶 ,IC50为 2.1 nM。 | |||
T4299 |
AS-2444697
|
IRAK | Immunology/Inflammation; NF-κB |
AS2444697 是一种口服有效的IRAK-4抑制剂,IC50为 21 nM。它对人和大鼠 IRAK-4 活性具有抑制作用。它通过抗炎作用表现出肾脏保护作用。 | |||
T9157 |
GP130 receptor agonist-1
N-(4-Fluorophenyl)-4-phenyl-2-thiazolami |
Interleukin | Immunology/Inflammation |
GP130 receptor agonist-1 (N-(4-Fluorophenyl)-4-phenyl-2-thiazolami) 是一种有效的、口服有活性的、可透过血脑屏障的 GP130受体激动剂。它对 NMDA 诱导的神经毒性具有神经保护作用。 | |||
T9203 |
JH-X-119-01
|
IRAK | Immunology/Inflammation; NF-κB |
JH-X-119-01 是白介素 1 受体相关激酶 1 的选择性抑制剂。它能够改善 LPS 诱导的小鼠败血症。它可以抑制 IRAK1(IC50:9 nM),在浓度达到 10 μM 时,也不会对 IRAK4 产生抑制作用。 | |||
T5354 |
IRAK4-IN-7
CA-4948 |
IRAK | Immunology/Inflammation; NF-κB |
IRAK4-IN-7 (CA-4948) 是白介素 1 受体相关激酶 4 (IRAK4) 的选择性抑制剂,口服有活性。它可用于研究癌症以及炎症疾病。 | |||
T9027 |
CA-4948
Emavusertib |
IRAK; FLT | Angiogenesis; Immunology/Inflammation; NF-κB; Tyrosine Kinase/Adaptors |
CA-4948 (Emavusertib) 是一种IRAK4抑制剂,也是一种FLT3抑制剂,具有抗肿瘤作用。 | |||
T11670 |
IRAK inhibitor 3
|
IRAK | Immunology/Inflammation; NF-κB |
IRAK inhibitor 3 是白细胞介素-1受体相关激酶调节剂。 | |||
T11635 |
IL-17A antagonist 1
|
IL Receptor | Immunology/Inflammation |
IL-17A antagonist 1 是一种 IL-17A 拮抗剂,可用于研究和白介素相关的炎症和免疫疾病。 | |||
T5641 |
RP-54745
|
Interleukin | Immunology/Inflammation |
RP-54745 是一种能抑制噬细胞刺激和的白介素-1 的产生的化合物,对风湿病的治疗具有潜在的研究价值。 | |||
T7368 |
IRAK inhibitor 2
IRAK-IN-2 |
IRAK | Immunology/Inflammation; NF-κB |
IRAK inhibitor 2 (IRAK-IN-2) 是一种有效的白细胞介素1受体相关激酶4(IRAK-4)抑制剂,具有潜在的抗癌和抗癌活性,可用于研究炎症相关性疾病。 | |||
T36534 |
SDZ 224-015
SDZ 224015 |
IL Receptor; Caspase | Apoptosis; Immunology/Inflammation; Proteases/Proteasome |
SDZ 224-015 是白细胞介素-1β(IL-1β)转化酶和 Caspase-1 的口服活性抑制剂。SDZ 224-015 具有抗 COVID-19 和抗炎活性,可减少角叉菜胶诱导的大鼠爪子水肿。 | |||
T77353 |
MyD88-IN-1
|
IL Receptor; NF-κB; TLR; MyD88 | Immunology/Inflammation; NF-κB |
MyD88-IN-1 是一种有效的 MyD88 抑制剂。MyD88-IN-1 具有抗炎活性,可抑制 Toll 样受体 (TLR) 和白细胞介素-1 (IL-1) 受体家族成员下游炎症信号通路 ,包括NF-κB 通路。MyD88-IN-1 可用于研究癌症和治疗炎症。 | |||
T41142 |
EM 163
|
IL Receptor; p38 MAPK; MyD88 | Immunology/Inflammation; MAPK |
EM 163是一种 TIR-TIR 相互作用抑制剂,它是MyD88蛋白的TIR(Toll/白细胞介素-1受体)结构域拟态。EM 163针对IL-1受体中的TIR 结构域,阻断与MyD88的相互作用。EM 163抑制葡萄球菌肠毒素B(SEB)引起的体内炎症细胞因子的产生。EM 163能保护小鼠免受SEB 冲击引起的死亡。在体外的大鼠海马神经元中,EM 163阻断p38的激活和IL-1β对化学诱导的长期电位(LTP)引发的蛋白质合成的抑制作用。 | |||
T2548 |
Diflorasone
|
Glucocorticoid Receptor | Endocrinology/Hormones |
Diflorasone 是一种皮质类固醇激素受体激动剂,具有抗炎和免疫抑制作用。它可通过细胞膜扩散进入细胞,并与细胞质中的糖皮质激素受体结合。它用于研究湿疹、牛皮癣等皮肤病。 | |||
T11672 | IRAK inhibitor 4 | Others | Others |
IRAK inhibitor 4 is an interleukin-1 receptor associated kinase 4 inhibitor. | |||
T13843 |
PROTAC IRAK4 ligand-1
|
Others | Others |
PROTAC IRAK4 ligand-1 is a synthetic ligand for interleukin-1 receptor-associated kinase 4. | |||
T28143 |
ND-2110
ND2110 |
Others | Others |
ND-2110, a selective interleukin-1 receptor-associated kinase 4 inhibitors, is used for the treatment of autoimmune disorders and lymphoid malignancy. | |||
T30953 |
CK 17
CK-17,CK17 |
Others | Others |
CK-17 is an interleukin-1 antagonist and an IL-1 blocker, which inhibits fibroblast proliferation in a concentration-dependent manner. | |||
T11697 |
IX 207-887
|
Others | Others |
IX 207-887 inhibits the release of interleukin-1 (IL-1). IX 207-887 is a novel antiarthritic agent. | |||
T68444 |
Dircin
|
Others | Others |
Dircin is an anti-inflammatory agent, prescribed for osteoarthritis and chronic inflammatory arthritis. It works by inhibiting interleukin-1. | |||
T39248 |
PF-06426779
|
Others | Others |
PF-06426779 is a potent and selective inhibitor of interleukin 1 receptor associated kinase 4 (IRAK4) , with an IC 50 of 0.3 nM. | |||
T19854 |
Evoxine
|
Others | Others |
Evoxine is a selective inhibitor of CO2-induced immune suppression. It inhibits hypercapnic suppression of interleukin-6 and the chemokine CCL2 expression in human THP-1 macrophages. | |||
T30959 |
CK-119
CK 119,GC-6119,UNII-AL53N923EI |
Others | Others |
CK-119 is an interleukin-1 blocker, which mainly inhibits the growth of fibroblast-like corneal and conjunctival cells by inhibiting the synthesis of DNA and RNA. | |||
T40225 |
JH-X-119-01 hydrochloride
|
Others | Others |
JH-X-119-01 hydrochloride is a potent and selective inhibitor of interleukin-1 receptor-associated kinases 1 (IRAK1). It effectively alleviates lipopolysaccharide (LPS)-induced sepsis in mice. | |||
T76256 |
Erepdekinra
|
||
Erepdekinra 是一种白细胞介素-17A (IL-17A) 受体拮抗剂。 | |||
T39903 |
PROTAC IRAK4 degrader-6
PROTAC IRAK4 degrader-6 |
Others | Others |
PROTAC IRAK4 degrader-6 is a potent Cereblon-based compound designed to degrade interleukin-1 receptor-associated kinase 4 (IRAK4). | |||
T76914 |
Avizakimab
|
||
Avizakimab (BOS161721) 是一种人源化IgG1单克隆抗体,靶向白介素-21 (IL-21)。 | |||
T80568 |
Casdozokitug
SRF-388 |
||
Casdozokitug (SRF-388) 是一种针对IL27的IgG1κ类型抗体。 | |||
T13842 |
PROTAC IRAK4 degrader-1
|
Others; PROTACs | Others; PROTAC |
PROTAC IRAK4 degrader-1 is a degrader of PROTAC interleukin-1 receptor-associated kinase 4 (IRAK4). | |||
T80576 |
Picankibart
|
||
Picankibart是一种专一针对IL23A的小鼠源IgG1κ单克隆抗体。 | |||
T34811 |
Terrein
NSC 291308,土曲霉酮,Terrain,(+)Terrein,NSC291308,NSC-291308 |
Others | Others |
Terrain, also known as NSC 291308, is a fungal metabolite with diverse biological activities. Terrein reduces age-related inflammation induced by oxidative stress through Nrf2/ERK1/2/HO-1 signalling in aged HDF cells. (+)-terrein suppresses interleukin-6/ | |||
T39901 |
PROTAC IRAK4 degrader-4
PROTAC IRAK4 degrader-4 |
Others | Others |
PROTAC IRAK4 degrader-4 (US20190192668A1, compound I-127) is a Cereblon-based PROTAC specifically designed to target and degrade interleukin-1 receptor-associated kinase 4 (IRAK4). | |||
T76823 | Perakizumab | ||
Perakizumab (RG4934)为针对IL-17A(Interleukin Related)的人源化IgG1κ单克隆抗体。适用于自身免疫性疾病(例如银屑病关节炎)的研究。 | |||
T23962 |
DA-E 5090
DA-E-5090,DA-E5090,DA E 5090 |
Others | Others |
DA-E 5090 is a pharmacologically active metabolite of E 5090, is an interleukin-1 antagonist. DA-E 5090 is a novel inhibitor of IL-1 generation, in vitro inhibitory effects on the generation of IL-1 by human monocytes. | |||
T76972 |
Tozorakimab
|
||
Tozorakimab (MEDI-3506) 是一种靶向白介素-33 (interleukin-33) 的人免疫球蛋白 G1 单克隆抗体。Tozorakimab 可用于研究慢性阻塞性肺疾病。 | |||
T76826 | Sirukumab | ||
Sirukumab (CNTO-136) 是一种人源化单克隆抗 IL6(Interleukin Related) IgG1κ 抗体。Sirukumab 具有用于活动性狼疮性肾炎研究的潜力。 | |||
T70367 |
SNU-BP
|
Others | Others |
SNU-BP is an agonist of PPAR-gamma, inhibiting lipopolysaccharide (LPS)-induced NO production and pro-inflammatory cytokines. SNU-BP potentiates interleukin-4-induced arginase-1 expression, and promotes microglial polarization toward an M2 anti-inflammatory phenotype. | |||
T80577 |
Varokibart
|
||
Varokibart (TEV-53275)为针对IL-5的人源化IgG4λ单克隆抗体。 | |||
T30215 |
AUY-954 free base
AUY 954,NVP-AUY954,AUY-954,AUY954 |
Others | Others |
AUY-954 is an effective selective S1P(1) modulator. It can significantly reduce the local expression of EAN rat sciatic nerve T cells, B cells, macrophage infiltration, inflammatory demyelination, interleukin-17 and matrix metalloproteinase-9. |
Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T2822 |
Ginsenoside Rb1
Gypenoside Ⅲ,人参皂苷Rb1,人参皂苷 Rb1,Gypenoside III |
ATPase; Mitophagy; IRAK; NF-κB; Autophagy; HSV | Autophagy; Immunology/Inflammation; Membrane transporter/Ion channel; Microbiology/Virology; NF-κB |
Ginsenoside Rb1 (Gypenoside Ⅲ) 是中药人参的成分,可能具有抑制或阻止肿瘤生长的特性。 | |||
T2932 |
Ginsenoside Rh1
Sanchinoside B2,人参皂苷 Rh1,人参皂苷Rh1,Prosapogenin A2,20(S)-Ginsenoside Rh1,Sanchinoside Rh1 |
IL Receptor; TNF; Endogenous Metabolite; PPAR; Interleukin | Apoptosis; DNA Damage/DNA Repair; Immunology/Inflammation; Metabolism |
Ginsenoside Rh1 (Sanchinoside B2) 是人参的一种主要成分,具有抗炎作用,抑制PPAR-γ,TNF-α,IL-6和IL-1β的表达。 | |||
T1168 |
Desonide
Tridesilon,地索奈德,Locapred,Prednacinolone |
Glucocorticoid Receptor | Endocrinology/Hormones |
Desonide (Prednacinolone) 是一种非氟化皮质类固醇抗炎剂,能够作用于糖皮质激素受体。 | |||
T1257 |
Bestatin
Ubenimex,乌苯美司 |
Others; Aminopeptidase; Antibacterial; Antibiotic; LTR | Immunology/Inflammation; Metabolism; Microbiology/Virology; Others |
Bestatin (Ubenimex) 是 CD13 (Aminopeptidase N)/APN 和 leukotriene A4 hydrolase 抑制剂,可用于癌症研究。 | |||
T3S0364 |
L-Arginine
L-精氨酸,L-Arg,(S)-(+)-Arginine |
IL Receptor; Endogenous Metabolite; NO Synthase | Immunology/Inflammation; Metabolism |
L-Arginine (L-Arg) 是内皮型一氧化氮合酶(eNOS) 的底物。L-Arginine 通过阳离子氨基酸转运体家族转运到血管平滑肌细胞,并被代谢成一氧化氮、多胺或 L-脯氨酸。 | |||
T6S1579 |
Monotropein
水晶兰苷,Monotropeine |
Others | Others |
Monotropein (Monotropeine) 是从Morinda officinalis 中获得,能够抑制硫酸葡聚糖硫酸钠诱导的结肠炎小鼠模型中炎性因子的表达。 | |||
T6S1597 |
Mulberroside A
桑皮苷 A,桑皮苷A |
TNF; Tyrosinase; Interleukin | Apoptosis; Immunology/Inflammation; Proteases/Proteasome |
Mulberroside A 是桑中的一种主要活性成分,可降低TNF-α、IL-1β和IL-6的表达,抑制 NALP3、caspase-1 和 NF-κB 的激活以及 ERK、JNK 和 p38 的磷酸化 。它抑制蘑菇酪氨酸酶,具有抗炎和抗细胞凋亡作用。 | |||
T2S2264 |
Linalool
Linalol,(±)-Linalool,Phantol,沉香醇 |
Apoptosis; IL Receptor; TNF; Endogenous Metabolite; iGluR | Apoptosis; Immunology/Inflammation; Membrane transporter/Ion channel; Metabolism; Neuroscience |
Linalool (Linalol) 是存在芫荽等植物中的单萜类天然产物,是竞争性NMDA 受体拮抗剂,具有抗肿瘤和抗心脏毒性的作用。它通过激活 Nrf2 诱导抗氧化防御和通过抑制 NF-κB 减少炎症反应来保护其免受 LPS/GalN 诱导的肝损伤,具有镇痛、抗菌和抗炎的特性。 | |||
TN5187 |
Triptoquinone B
|
IL Receptor | Immunology/Inflammation |
Triptoquinone B is a novel interleukin-1 inhibitor, shows extremely potent inhibitory activities against interleukin-lα and β releases for human peripheral mononticlear cells, it shows the significant immunosuppressive activity. | |||
TN5186 |
Triptoquinone A
|
IL Receptor; NOS | Immunology/Inflammation |
Triptoquinone A may be a useful candidate for the development of a drug as a potent inhibitor of iNOS gene over-expression. Triptoquinone A has anti-inflammatory activity, it prevents ndotoxin-or interleukin-1 beta-promoted induction of nitric oxide synth |
Cat. No. | Product Name | Species | Expression System |
---|---|---|---|
TMPY-02568 |
IL-1 beta/IL-1F2 Protein, Canine, Recombinant
interleukin 1, beta,IL-1 β,in... |
Canine | E. coli |
IL-1 beta/IL-1F2 Protein, Canine, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 17.6 kDa and the accession number is Q28292. | |||
TMPY-02824 |
IL-18R alpha Protein, Rat, Recombinant (hFc)
interleukin 18 receptor 1 |
Rat | HEK293 Cells |
IL-18R alpha Protein, Rat, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 62.5kDa and the accession number is A0A8I6A1C2. | |||
TMPY-03951 |
IL-18R alpha Protein, Cynomolgus, Recombinant (hFc)
interleukin 18 receptor 1 |
Cynomolgus | HEK293 Cells |
IL-18R alpha Protein, Cynomolgus, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 61.1 kDa and the accession number is F7H8F9. | |||
TMPY-05840 |
IL-1RAP/IL-1RAcP Protein, Cynomolgus, Recombinant (His)
interleukin 1 receptor accessory protein |
Cynomolgus | HEK293 Cells |
IL-1RAP/IL-1RAcP Protein, Cynomolgus, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 40.56 kDa and the accession number is P59822-1. | |||
TMPY-02227 |
IL-1 beta/IL-1F2 Protein, Rat, Recombinant (mature form)
白细胞介素,interleukin 1, beta,白介素,interleu... |
Rat | E. coli |
IL-1 beta/IL-1F2 Protein, Rat, Recombinant (mature form) is expressed in E. coli expression system. The predicted molecular weight is 17.4 kDa and the accession number is Q63264-1. | |||
TMPY-01738 |
IL-1 alpha/IL-1A Protein, Mouse, Recombinant
interleukin 1, α,IL-1 α/IL1 |
Mouse | E. coli |
IL-1 alpha/IL-1A Protein, Mouse, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 18 kDa and the accession number is P01582. | |||
TMPY-02445 |
IL-1 beta/IL-1F2 Protein, Rhesus, Recombinant
interleukin 1, beta,IL-1 β,白介素, |
Rhesus | E. coli |
IL-1 beta/IL-1F2 Protein, Rhesus, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 17.5 kDa and the accession number is P48090. | |||
TMPY-00437 |
IL-11R alpha chain 1/IL-11RA1 Protein, Rat, Recombinant (His)
Il11ra1,interleukin ... |
Rat | HEK293 Cells |
IL-11R alpha chain 1/IL-11RA1 Protein, Rat, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 39.1 kDa and the accession number is A6IIX5. | |||
TMPY-01376 |
IL-18R alpha Protein, Mouse, Recombinant (His)
Il1rrp,Il18ralpha,interleukin |
Mouse | HEK293 Cells |
IL-18R alpha Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 36.8 kDa and the accession number is Q61098. | |||
TMPY-05782 |
IL-18R alpha Protein, Mouse, Recombinant (mFc)
Il18rα,Il1rrp,interleukin 1 |
Mouse | HEK293 Cells |
IL-18R alpha Protein, Mouse, Recombinant (mFc) is expressed in HEK293 mammalian cells with mFc tag. The predicted molecular weight is 61.74 kDa and the accession number is Q61098. | |||
TMPY-01862 |
IL-4 Protein, Human, Recombinant
Interleukin-4,IL-4,BCGF1,白细胞介素,interle... |
Human | E. coli |
IL-4 Protein, Human, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 15.1 kDa and the accession number is P05112-1. | |||
TMPY-01258 |
IL-13RA1 Protein, Human, Recombinant (His)
NR4,interleukin 13 receptor, alpha 1 |
Human | HEK293 Cells |
IL-13RA1 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 38.3 kDa and the accession number is P78552-1. | |||
TMPJ-00162 |
IL-1 alpha/IL-1A Protein, Human, Recombinant (hFc)
Hematopoietin-1,Interleukin-1 Alp... |
Human | HEK293 Cells |
IL-1 alpha/IL-1A Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with C-Fc tag. The predicted molecular weight is 54 KDa and the accession number is P01583. | |||
TMPY-03079 |
IL-1R2 Protein, Mouse, Recombinant (His)
interleukin 1 receptor, type II,Il1 |
Mouse | HEK293 Cells |
IL-1R2 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 39.6 kDa and the accession number is P27931. | |||
TMPY-01170 |
IL-13RA1 Protein, Mouse, Recombinant (His)
interleukin 13 receptor, α1,CD2 |
Mouse | HEK293 Cells |
IL-13RA1 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 37.6 kDa and the accession number is O09030. | |||
TMPY-02134 |
IL-1 beta/IL-1F2 Protein, Mouse, Recombinant
Il-1b,IL-1beta,白细胞介素,interleukin ... |
Mouse | E. coli |
IL-1 beta/IL-1F2 Protein, Mouse, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 17.5 kDa and the accession number is P10749. | |||
TMPY-02558 |
IL-4 Protein, Mouse, Recombinant
白介素,白细胞介素,BSF-1,Il-4,interleukin 4 |
Mouse | E. coli |
IL-4 Protein, Mouse, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 13.4 kDa and the accession number is P07750. | |||
TMPJ-00038 |
IL-7 Protein, Mouse, Recombinant (His)
interleukin-7,白介素,IL-7,IL-7 interleukin-7,... |
Mouse | HEK293 Cells |
Mouse interleukin-7(IL-7) is the member of hemopoietin family which is important to the differentiation, proliferation, and survival of lymphocyte. Mouse IL-7 shares approximately 88% aa sequence identity with rat IL-7 and 58-60% with human, equine, bovine, ovine, porcine, feline and canine IL-7. It is widely expressed in primary and secondary lymphoid tissues cell and stromal epithelial cells of the thymus, bone marrow, and intestines. IL-7 activation of IL-7 R alpha is critical for both T cell... | |||
TMPY-01999 |
IL-1 beta/IL-1F2 Protein, Human, Recombinant (His)
IL-1,IL1-β,白介素,IL1-BETA,白细胞介素,IL<... |
Human | E. coli |
IL-1 beta/IL-1F2 Protein, Human, Recombinant (His) is expressed in E. coli expression system with His tag. The predicted molecular weight is 32.3 kDa and the accession number is P01584. | |||
TMPY-03802 |
IL-17F Protein, Human, Recombinant (aa 31-163)
ML1,ML-1,IL-17F,interleukin |
Human | E. coli |
IL-17F Protein, Human, Recombinant (aa 31-163) is expressed in E. coli expression system. The predicted molecular weight is 15.1 kDa and the accession number is AAH70124.1. | |||
TMPY-05593 |
IL-1RAP/IL-1RAcP Protein, Human, Recombinant (His & Avi), Biotinylated
IL-1RAcP,interleukin 1 receptor a... |
Human | HEK293 Cells |
IL-1RAP/IL-1RAcP Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with His and Avi tag. The predicted molecular weight is 42.4 kDa and the accession number is Q9NPH3-1. | |||
TMPY-01701 |
IL-12RB1 Protein, Human, Recombinant (His)
interleukin 12 receptor, β1,IL |
Human | HEK293 Cells |
IL-12RB1 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 58.5 kDa and the accession number is P42701-1. | |||
TMPY-05491 |
IL-18R alpha Protein, Human, Recombinant (hFc)
CDw218a,interleukin 18 receptor <... |
Human | HEK293 Cells |
IL-18R alpha Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 62.5 kDa and the accession number is Q13478. | |||
TMPY-01049 |
IL-1 beta/IL-1F2 Protein, Human, Recombinant
IL-1 beta,interleukin 1, beta,IL-... |
Human | E. coli |
IL-1 beta/IL-1F2 Protein, Human, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 17 kDa and the accession number is P01584. | |||
TMPY-01219 |
IL-18R alpha Protein, Human, Recombinant (His)
CDw218a,interleukin 18 receptor <... |
Human | HEK293 Cells |
IL-18R alpha Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 37.2 kDa and the accession number is Q13478. | |||
TMPY-00856 |
TCCR Protein, Human, Recombinant (hFc)
WSX1,interleukin 27 receptor, α,IL27R,TCCR... |
Human | HEK293 Cells |
TCCR Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 79 kDa and the accession number is Q6UWB1. | |||
TMPY-06981 |
IL-1 alpha/IL-1A Protein, Human, Recombinant (E. coli)
interleukin 1 α,IL1,白介素,IL-1<... |
Human | E. coli |
IL-1 alpha is a member of the interleukin 1 cytokine family. Cytokines are proteinaceous signaling compounds that are major mediators of the immune response. They control many different cellular functions including proliferation, differentiation, and cell survival/apoptosis but are also involved in several pathophysiological processes including viral infections and autoimmune diseases. Cytokines are synthesized under various stimuli by a variety of cells of both the innate (monocytes, macrophage... | |||
TMPY-00854 |
IL-1 alpha/IL-1A Protein, Human, Recombinant
IL-1F1,interleukin 1, α,... |
Human | HEK293 Cells |
IL-1 alpha/IL-1A Protein, Human, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 18 kDa and the accession number is P01583. | |||
TMPY-04096 |
ST2/IL-1 RL1 Protein, Mouse, Recombinant (His)
Ly84,St2-rs1,T1,ST2L,T1/ST2,Fit-<... |
Mouse | HEK293 Cells |
ST2/IL-1 RL1 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 36.5 kDa and the accession number is P14719-1. | |||
TMPY-04580 |
IL-1RAP/IL-1RAcP Protein, Mouse, Recombinant (His)
AI255955,6430709H04Rik,IL-1RAcP,AV239853,interl... |
Mouse | HEK293 Cells |
IL-1RAP/IL-1RAcP Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 39.7 kDa and the accession number is Q3UEL3. | |||
TMPY-04793 |
IL-35 Protein, Human, Recombinant (Flag & His)
NKSF1,P35,白介素,Interleukin-35,CLMF,白细胞介素,NF... |
Human | HEK293 Cells |
IL-35 Protein, Human, Recombinant (Flag & His) is expressed in HEK293 mammalian cells with Flag and His tag. The predicted molecular weight is 48.3 kDa and the accession number is P29459-1. | |||
TMPY-00850 |
ST2/IL-1 RL1 Protein, Human, Recombinant
ST2,IL1RL1,ST2L,IL33R,T1,DER4,ST2... |
Human | HEK293 Cells |
ST2/IL-1 RL1 Protein, Human, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 35.6 kDa and the accession number is Q01638-2. | |||
TMPY-00849 |
ST2/IL-1 RL1 Protein, Human, Recombinant (hFc)
ST2V,FIT-1,DER4,interleukin 1 rec... |
Human | HEK293 Cells |
ST2/IL-1 RL1 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 61.72 kDa and the accession number is Q01638-2. | |||
TMPY-01359 |
ST2/IL-1 RL1 Protein, Human, Recombinant (His)
IL1RL1,IL‑1 R4,DER4,ST2,IL33R, |
Human | HEK293 Cells |
ST2/IL-1 RL1 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 36.5 kDa and the accession number is Q01638-2. | |||
TMPJ-01210 |
IL-33 Protein, Mouse, Recombinant
Interleukin-1 family member 1... |
Mouse | E. coli |
Mouse Interleukin 33 (IL-33) is a 30 kDa proinflammatory cytokine which may also regulates gene transcription in producer cells. IL-33 is constitutively expressed in smooth muscle and airway epithelia. IL-33 was identified based on sequence and structural homology with IL-1 family cytokines. It is up‑regulated in arterial smooth muscle, dermal fibroblasts, and keratinocytes following IL-1 alpha or IL‑1 beta stimulation. IL-33 is structurally related to IL-1, which induces helper T cells to produ... | |||
TMPY-01894 |
SIGIRR Protein, Human, Recombinant (His)
TIR8,single immunoglobulin and toll-interleukin |
Human | HEK293 Cells |
SIGIRR Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 14 kDa and the accession number is Q6IA17-1. | |||
TMPY-04483 |
IRAK4 Protein, Human, Recombinant (His)
IPD1,NY-REN-64,REN64,interleukin-1 |
Human | Baculovirus Insect Cells |
Interleukin-1 receptor-associated kinase 4, also known as Renal carcinoma antigen NY-REN-64, IRAK-4, and IRAK4, is a member of the protein kinase superfamily, TKL Ser/Thr protein kinase family, and Pelle subfamily. IRAK4 contains one death domain and one protein kinase domain. IRAK4 is required for the efficient recruitment of IRAK1 to the IL-1 receptor complex following IL-1 engagement, triggering intracellular signaling cascades leading to transcriptional up-regulation and mRNA stabilization. ... | |||
TMPJ-00035 |
IL-4 Protein, Human, Recombinant (His)
Pitrakinra,Binetrakin,B-Cell Stimulatory Factor 1,I... |
Human | HEK293 Cells |
IL-4 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with C-6xHis tag. The predicted molecular weight is 18 KDa and the accession number is P05112. | |||
TMPY-00864 |
IL-6R Protein, Human, Recombinant (His)
IL-6R-1,IL-6RA,IL6Q,CD126,interleukin<... |
Human | HEK293 Cells |
IL-6R Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 40 kDa and the accession number is A0N0L5. | |||
TMPY-05278 |
IL-6R Protein, Human, Recombinant (hFc)
IL-6R-1,CD126,gp80,IL6Q,IL6RQ,IL-6R,IL-6RA... |
Human | HEK293 Cells |
IL-6R Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 65.3 kDa and the accession number is A0N0L5. | |||
TMPY-01366 |
IL-1R2 Protein, Human, Recombinant (His)
IL1R2c,interleukin 1 receptor, ty... |
Human | HEK293 Cells |
IL-1R2 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 39.2 kDa and the accession number is P27930-1. | |||
TMPY-01047 |
IL-1R1 Protein, Human, Recombinant (hFc)
IL-1R-α,IL-1 RI,IL-1R-alpha,IL- |
Human | HEK293 Cells |
IL-1R1 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 63 kDa and the accession number is P14778. | |||
TMPY-02926 |
IL-2RG Protein, Human, Recombinant (hFc)
SCIDX1,interleukin 2 receptor, gamma,CIDX,... |
Human | HEK293 Cells |
IL-2RG Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 54.4 kDa and the accession number is P31785. | |||
TMPY-00472 |
IL-8/CXCL8 Protein, Human, Recombinant (aa 28-99)
NAF,GCP1,NAP1,chemokine (C-X-C motif) liga... |
Human | E. coli |
IL-8/CXCL8 Protein, Human, Recombinant (aa 28-99) is expressed in E. coli expression system. The predicted molecular weight is 8.5 kDa and the accession number is A0A024RDA5. | |||
TMPY-00853 |
IL-1RA Protein, Human, Recombinant
DIRA,IL1RA,interleukin 1 receptor... |
Human | E. coli |
IL-1RA Protein, Human, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 17.3 kDa and the accession number is P18510-1. | |||
TMPY-04726 |
IL-8/CXCL8 Protein, Human, Recombinant (His)
Interleukin-8,GCP1,MONAP,LECT,LYNAP,NAF,GC... |
Human | P. pastoris (Yeast) |
IL-8/CXCL8 Protein, Human, Recombinant (His) is expressed in yeast with His tag. The predicted molecular weight is 9.8 kDa and the accession number is A0A024RDA5. | |||
TMPY-03481 |
IL-1R2 Protein, Human, Recombinant
白细胞介素,IL1R2c,IL1RB,IL-1RT2,IL- |
Human | HEK293 Cells |
IL-1R2 Protein, Human, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 38.4 kDa and the accession number is P27930-1. | |||
TMPY-01250 |
IL-11R alpha/IL-11RA Protein, Mouse, Recombinant (His)
AI314697,Il11ra1,int... |
Mouse | HEK293 Cells |
IL-11R alpha/IL-11RA Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 39.2 kDa and the accession number is Q64385. | |||
TMPJ-00850 |
ST2/IL-1 RL1 Protein, Mouse, Recombinant (aa 27-337, His)
Protein T1,suppression of tumorigenicity 2,Ly84,DER... |
Mouse | HEK293 Cells |
ST2/IL-1 RL1 Protein, Mouse, Recombinant (aa 27-337, His) is expressed in HEK293 mammalian cells with C-6xHis tag. The predicted molecular weight is 55-70 KDa and the accession number is P14719-2. | |||
TMPY-00754 |
IL-8/CXCL8 Protein, Human, Recombinant (aa 23-99)
MONAP,MDNCF,NAP-1,白介素,NAP1,LUCT,chemokine ... |
Human | HEK293 Cells |
IL-8/CXCL8 Protein, Human, Recombinant (aa 23-99) is expressed in HEK293 mammalian cells. The predicted molecular weight is 8 kDa and the accession number is A0A024RDA5. | |||
------------------------ 更多 ------------------------ |
Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
TMID-0254 |
Linalool-d3
|
||
Linalool-d3 是 Linalool 的氘代化合物。Linalool 的 CAS 号为 78-70-6。Linalool 是存在芫荽等植物中的单萜类天然产物,是竞争性NMDA受体拮抗剂,具有抗肿瘤和抗心脏毒性的作用。它通过激活 Nrf2 诱导抗氧化防御和通过抑制 NF-κB 减少炎症反应来保护其免受 LPS/GalN 诱导的肝损伤,具有镇痛、抗菌和抗炎的特性。 |