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Search Results for " inos "

Targets Recommended: NOS

286

抑制剂 & 化合物

177

天然产物

1

化合物库

25

重组蛋白

4

同位素标记化合物

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Cat. No.	Product Name
L2900	氧化还原化合物库		1264 compounds
	1264 个活性化合物，已经验证具有一定的抗氧化活性，包括 ROS 清除剂、iNOS、eNOS、及抗氧化的天然产物，是研究疾病机理以及药物研究的优良载体

化合物库

氧化还原化合物库

Cat.No: L2900

Compounds: 1264

Cat. No.	Product Name	Target	Signaling Pathways
T83625	iNOS-IN-14 3-bromo-1H-indazole-7-carbonitrile	NOS	Immunology/Inflammation
	iNOS-IN-14 (3-bromo-1H-indazole-7-carbonitrile) 是一种有效的一氧化氮合酶(NOS)抑制剂，抑制nNOS的NADPH氧化酶活性。
T62849	iNOS-IN-2	Others	Others
	iNOS-IN-2 (Compound 53) 是一种有效的诱导型一氧化氮合酶 (iNOS) 蛋白下调剂。iNOS-IN-2 能够有效抑制 NO 产生 (IC50: 6.4 μM)。iNOS-IN-2 能够用于慢性炎症的研究。
T62987	iNOs-IN-1	Others	Others
	iNOs-IN-1 (YPW) 是一种诱导型一氧化氮合酶 (inducible nitric oxide synthase,iNOS) 的有效抑制剂，具有抗炎作用。iNOs-IN-1 在小鼠巨噬细胞中，能够以剂量依赖性的方式明显抑制 IL-6 和 iNOS 的表达，对 LPS 诱导的 NO 生成也具有抑制作用。
T72638	iNOS inhibitor-10	NO Synthase	Immunology/Inflammation
	iNOSinhibitor-10 (Compound 1b)作为iNOS抑制剂，显示出对三阴性乳腺癌细胞的抗增殖能力，其IC50值为65 nM。
T63261	iNOs-IN-3	Others	Others
	iNOs-IN-3 是口服具有活力的一氧化氮合成酶 (iNOS) 抑制剂，IC50 值为 3.342 μM，表现出抗炎作用，能够用于研究 LPS 诱导的急性肺损伤 (ALI) 。
T63104	iNOS/PGE2-IN-1	Others	Others
	iNOS/PGE2-IN-1 是一种 iNOS/PGE2 抑制剂，是一种有效的抗炎剂。iNOS/PGE2-IN-1 对 LPS 诱导的 NO 产生表现出抑制作用，具有低致溃疡倾向。
T21700	NOS-IN-1 2-Imino-4-methylpiperidine (acetate)	NOS	Immunology/Inflammation
	NOS-IN-1 (2-Imino-4-methylpiperidine acetate) 是有效的、具有口服活性的一氧化氮合酶 (NOS) 的抑制剂。NOS-IN-1抑制人 iNOS (hiNOS)，hnNOS 和 heNOS 的 IC50 分别为 0.1 μM，0.2 μM 和1.1 μM。
T19916	TRIM 1-(2-Trifluoromethylphenyl)imidazole,1-(2-三氟甲基苯基)咪唑	NOS	Immunology/Inflammation
	TRIM (1-(2-Trifluoromethylphenyl)imidazole) 是一氧化氮合酶抑制剂。它在体外能够抑制小鼠小脑 nNOS (IC50:28.2 µM)，以及大鼠肺 iNOS (IC50:27.0 µM)。它拥有抗焦虑以及抗抑郁的能力。
T22419	S-Methylisothiourea sulfate (S)-Methylisothiourea sulfate,S-甲基异硫脲硫酸盐,S-甲基异硫脲半硫酸盐	NOS; NO Synthase; HSV	Immunology/Inflammation; Microbiology/Virology
	S-Methylisothiourea sulfate ((S)-Methylisothiourea sulfate) 是一种选择性 iNOS 抑制剂，在感染性休克的啮齿动物模型中发挥有益作用。
T1127	Beclometasone dipropionate Beclovent,Beclomethasone dipropionate,二丙酸倍氯米松,丙酸倍氯米松,Beconase,Vancenase	Glucocorticoid Receptor	Endocrinology/Hormones
	Beclometasone dipropionate (Vancenase) 是具有口服活性的糖皮质激素，具有抗炎和免疫抑制作用。它是Betamethasone 的前体药物，Betamethasone 是 LPS 诱导的炎症及 MMP 释放的抑制剂。
T23046	N-tert-butyl-α-Phenylnitrone (Z)-N-benzylidene-2-Methylpropan-2-aMine oxide,N-叔丁基-α-苯基硝酮	ROS; COX	Immunology/Inflammation; Neuroscience
	N-tert-butyl-α-Phenylnitrone ((Z)-N-benzylidene-2-Methylpropan-2-aMine oxide) 是基于硝酮的自由基清除剂，可形成一氧化氮自旋加合物。它可以穿透血脑屏障，抑制 COX2的催化活性，有 ROS 清除、抗炎、神经保护、抗衰老和抗糖尿病的作用。
T6055	Quisinostat 奎诺司他,JNJ-26481585	Apoptosis; HDAC; Autophagy	Apoptosis; Autophagy; Chromatin/Epigenetic; DNA Damage/DNA Repair
	Quisinostat (JNJ-26481585) 是一种高效的，具有口服活性的 pan-HDAC 抑制剂，对 HDAC1、HDAC2、HDAC4、HDAC10、HDAC11 作用的 IC50值范围为 0.11-0.64 nM。它在成神经细胞瘤中能诱导自噬，具有广泛的抗肿瘤活性。
T12516	Polyinosinic-polycytidylic acid sodium 双链聚肌胞,Poly(I:C) sodium	Apoptosis; Others; TLR	Apoptosis; Immunology/Inflammation; Others
	Polyinosinic-polycytidylic acid sodium (Poly(I:C) sodium) 是双链 RNA 的合成类似物，是TLR3和视黄酸诱导型基因 I 受体激动剂。它可以用作疫苗佐剂，直接触发癌细胞发生凋亡，还增强先天性和适应性免疫反应，并改变肿瘤的微环境。
T4370	Resminostat hydrochloride 4SC-201 hydrochloride,RAS2410 hydrochloride	HDAC	Chromatin/Epigenetic; DNA Damage/DNA Repair
	Resminostat hydrochloride (RAS2410 hydrochloride) 是HDAC1，HHDAC3和HDAC6抑制剂，IC50值分别为 42.5、50.1和71.8 nM，对 HDAC8 的活性较低，IC50值为 877 nM。
T6279L	Givinostat hydrochloride ITF2357 hydrochloride,Givinostat HCl,ITF2357,ITF 2357,ITF-2357,ITF2357 HCl	HDAC	Chromatin/Epigenetic; DNA Damage/DNA Repair
	Givinostat hydrochloride (ITF2357 hydrochloride) 是一种 HDAC 抑制剂，对 HDAC1 和 HDAC3 的 IC50 分别为 198 和 157 nM。 Givinostat hydrochloride 具有抗炎、抗血管生成和抗肿瘤活性。
TNU0810	2′-C-Methyl-6-O-methylinosine 2′-C-Methyl-6-O-methylinosine	Nucleoside Antimetabolite/Analog	Cell Cycle/Checkpoint; DNA Damage/DNA Repair
	2′-C-Methyl-6-O-methylinosine (2′-C-Methyl-6-O-methylinosine) 是一种次黄嘌呤类似物，具有广泛的实物活性，可用于研究多种肿瘤疾病。
T4481	Tucidinostat HBI-8000,Chidamide,西达本胺,CS 055	HDAC	Chromatin/Epigenetic; DNA Damage/DNA Repair
	Tucidinostat (Chidamide) 是一种 HDAC 抑制剂，对 HDAC1、HDAC2、HDAC3、HDAC10 有抑制活性 (IC50=95/160/67/78 nM)。Tucidinostat 具有抗肿瘤活性，可以用于治疗 T 细胞白血病-淋巴瘤。
T9835	4-QUinolinecarboxamide, N-[3-[[[2-[4-(aminosulfonyl)phenyl]ethyl]amino]carbonyl]phenyl]-1,2-dihydro-2-oxo-	Others	Others
	4-QUinolinecarboxamide, N-[3-[[[2-[4-(aminosulfonyl)phenyl]ethyl]amino]carbonyl]phenyl]-1,2-dihydro-2-oxo-是胺。
T1890	Pracinostat SB939	Apoptosis; HDAC	Apoptosis; Chromatin/Epigenetic; DNA Damage/DNA Repair
	Pracinostat (SB939) 是一种组蛋白去乙酰化酶抑制剂，对 HDACs 的IC50值为 40-140 nM，可用于研究癌症。
T3614	Inosine pranobex Groprinosin,Isoprinosine,异丙肌苷,Immunovir,Delimmun	IL Receptor; HIV Protease	Immunology/Inflammation; Microbiology/Virology; Proteases/Proteasome
	Inosine pranobex (Delimmun) 是一种免疫增强剂，它是一种广谱抗病毒剂，用于 HIV 感染。
T8551	Nitrobenzylthioinosine NBMPR,S-(4-硝基苄基)-6-硫代肌苷	AChR; Adenosine Receptor	GPCR/G Protein; Neuroscience
	Nitrobenzylthioinosine (NBMPR) 是一种 ENT1 转运蛋白抑制剂，可与 ENT1 转运蛋白以高亲和力结合。它是一种可穿过血脑屏障的光亲和探针，用于追踪大脑中腺苷的摄取位点。
T8517	Belinostat PX105684,PXD101,贝利司他,PXD-101	HDAC; Autophagy	Autophagy; Chromatin/Epigenetic; DNA Damage/DNA Repair
	Belinostat (PXD101) 是一种异羟肟酸型组蛋白脱乙酰酶抑制剂，具有抗肿瘤活性，在 HeLa 细胞提取物中的IC50为 27 nM。
T1583	Vorinostat MK0683,伏立诺他,suberoylanilide hydroxamic acid,SAHA	Apoptosis; Mitophagy; Virus Protease; HDAC; Autophagy	Apoptosis; Autophagy; Chromatin/Epigenetic; DNA Damage/DNA Repair; Microbiology/Virology
	Vorinostat (SAHA) 是一种泛的组蛋白脱乙酰酶 (HDAC) 抑制剂 (IC50=10 nM)，对 HDAC1/2/3/6/7/11 均有抑制活性。 Vorinostat 具有抗肿瘤活性，可以诱导细胞分化，阻滞细胞周期，诱导细胞凋亡。
T1296	4-Aminosalicylic acid Aminosalicylic acid,4-aminosalicylate,para-aminosalicylic acid,对氨水杨酸,Aminopar	NF-κB; Lipoxygenase; COX; Glutathione Peroxidase; Antibacterial; Antibiotic	Immunology/Inflammation; Metabolism; Microbiology/Virology; Neuroscience; NF-κB
	4-Aminosalicylic acid (para-aminosalicylic acid) 是一种具有口服活性的抗生素，可研究肺结核病。
T16729	Remetinostat SHP-141	HDAC	Chromatin/Epigenetic; DNA Damage/DNA Repair
	Remetinostat (SHP-141) 是一种基于异羟肟酸的组蛋白脱乙酰酶抑制剂，可用于治疗皮肤 T 细胞淋巴瘤的研究。
T2454	Dacinostat NVP-LAQ824,达西司特,LAQ824	HDAC; Autophagy	Autophagy; Chromatin/Epigenetic; DNA Damage/DNA Repair
	Dacinostat (NVP-LAQ824) 是一种新型 HDAC 抑制剂，IC50 为 32 nM，是 p21 启动子的激活剂。它也可抑制HDAC1的活性，IC50值为 9 nM，主要用于癌症研究。
T6279	Givinostat hydrochloride monohydrate ITF2357,ITF-2357 hydrochloride monohydrate,Givinostat,Gavinostat hydrochloride monohydrate,吉维司他	HDAC	Chromatin/Epigenetic; DNA Damage/DNA Repair
	Givinostat hydrochloride monohydrate (ITF2357) 是一种HDAC 抑制剂，对HDAC1和HDAC3的IC50分别为 198 nM 和 157 nM。
T2078	Fimepinostat CUDC-907,PI3K/HDAC Inhibitor,CUDC 907	Apoptosis; PI3K; HDAC	Apoptosis; Chromatin/Epigenetic; DNA Damage/DNA Repair; PI3K/Akt/mTOR signaling
	Fimepinostat (CUDC 907) 是一种 I 型PI3K 及 I 和 II 型HDAC 酶抑制剂，作用于 PI3Kα/PI3Kβ/PI3Kδ 和 HDAC1/HDAC2/HDAC3/HDAC10 ，IC50分别为 19/54/39 nM 和 1.7/5.0/1.8/2.8 nM。
T0431	Abexinostat CRA 24781,阿贝司他,PCI24781,PCI-24781,PCI 24781,CRA 024781	HDAC	Chromatin/Epigenetic; DNA Damage/DNA Repair
	Abexinostat (PCI24781) 是一种新型的泛HDAC 抑制剂，对HDAC1的Ki 值为7 nM。
T6362	Domatinostat 4SC202,4SC 202,4SC-202 (free base),4SC-202	Apoptosis; HDAC	Apoptosis; Chromatin/Epigenetic; DNA Damage/DNA Repair
	Domatinostat (4SC202) 是一种 I 型 HDAC 抑制剂，能够抑制 HDAC1、HDAC2和 HDAC3 的活性，IC50值分别为 1.20 μM、1.12 μM 和 0.57 μM，同时能够抑制组蛋白赖氨酸特异性脱甲基酶1 的活性。
T27083	Crebinostat	Epigenetic Reader Domain; Histone Acetyltransferase; HDAC	Chromatin/Epigenetic; DNA Damage/DNA Repair
	Crebinostat 是一种有效的组蛋白去乙酰化酶 (HDAC) 抑制剂，对 HDAC1、HDAC2、HDAC3 和 HDAC6 有抑制作用， IC50 分别为 0.7 nM、1.0 nM、2.0 nM 和 9.3 nM。Crebinostat 可增加在体外神经元的突触蛋白 1 斑点沿树突 (synapsin-1 punctae along dendrites) 的密度。Crebinostat 可调节染色质介导的神经可塑性，增强小鼠的记忆。Crebinostat 可诱导组蛋白 H3 和组蛋白 H4 乙酰化，并增强 cAMP 反应元件结合蛋白 (CREB) 靶基因 Egr1 的表达。
T1852	Rac-Belinostat NSC726630,PXD101,PX-105684	HDAC	Chromatin/Epigenetic; DNA Damage/DNA Repair
	Rac-Belinostat (PX-105684) 是一种具有抗肿瘤活性的新型异羟肟酸型组蛋白脱乙酰酶 (HDAC) 抑制剂。 Belinostat 靶向 HDAC 酶，从而抑制肿瘤细胞增殖、诱导细胞凋亡、促进细胞分化和抑制血管生成。这种药物可以使耐药肿瘤细胞对其他抗肿瘤药物敏感，可能是通过一种涉及胸苷酸合酶下调的机制。
T71138L	Binospirone MDL 73005EF	5-HT Receptor	GPCR/G Protein; Neuroscience
	Binospirone (MDL 73005EF) 是一种 5-HT1A 受体激动剂，具有抗焦虑活性，可用于研究青光眼和与神经功能障碍相关的运动障碍。
T3661	Citarinostat ACY241,HDAC-IN-2	HDAC	Chromatin/Epigenetic; DNA Damage/DNA Repair
	Citarinostat (ACY241) 是一种强效、选择性和口服组蛋白脱乙酰酶 (HDAC) 抑制剂，具有抗肿瘤活性，对 HDAC1、HDAC2、HDAC3、HDAC6 和 HDAC8 的 IC50分别为 35、45、46、2.6 和 137 nM。
T2383	Panobinostat 帕比司他,NVP-LBH589,LBH589	Apoptosis; HIV Protease; HDAC; Autophagy	Apoptosis; Autophagy; Chromatin/Epigenetic; DNA Damage/DNA Repair; Microbiology/Virology; Proteases/Proteasome
	Panobinostat (NVP-LBH589) 是一种广谱的 HDAC 抑制剂 (IC50=5 nM)，具有口服活性和非选择性。Panobinostat 具有抗肿瘤活性，可以诱导细胞凋亡和自噬。
T0598	Iminostilbene 亚氨基芪,Dibenzazepine	Others	Others
	Iminostilbene (Dibenzazepine) 是 carbamazepine 的化学前体，主要用于治疗癫痫和神经性疼痛。
T4477	Domatinostat tosylate 4SC-202 tosylate,4SC-202	Apoptosis; HDAC	Apoptosis; Chromatin/Epigenetic; DNA Damage/DNA Repair
	Domatinostat tosylate (4SC-202) 是一种 I 型 HDAC 抑制剂，能够抑制 HDAC1、HDAC2和 HDAC3 的活性，IC50值分别为 1.20 μM、1.12 μM 和 0.57 μM。它也抑制组蛋白赖氨酸特异性脱甲基酶1 的活性。
T0020	Sodium 4-aminosalicylate dihydrate 对氨基水杨酸钠二水合物,Sodium 4-Aminosalicylate,4-Amino-salicylic acid sodium salt	Free radical scavengers; NF-κB; Antibacterial; Antibiotic	Microbiology/Virology; NF-κB; oxidation-reduction
	Sodium 4-aminosalicylate dihydrate (4-Amino-salicylic acid sodium salt) 是一种抗耐药性结核化合物。
T4509	Inositol nicotinate Inositol niacinate,Hexanicotol,Myo-Inositol hexanicotinate,Mesotal,肌醇烟酸酯,Dilexpal,Inositol hexanicotinate	Others	Others
	Inositol nicotinate (Mesotal) 是一种血管扩张剂，可用于研究外周动脉疾病。
T6481	Droxinostat NS 41080,4-(4-氯-2-甲基苯氧基)-N-羟基丁酰胺	Apoptosis; HDAC	Apoptosis; Chromatin/Epigenetic; DNA Damage/DNA Repair
	Droxinostat (NS 41080) 是HDAC3、HDAC6和HDAC8抑制剂，IC50分别为16.9、2.47和1.46 μM。
T2489	Ricolinostat ACY-1215,Rocilinostat	Apoptosis; HDAC	Apoptosis; Chromatin/Epigenetic; DNA Damage/DNA Repair
	Ricolinostat (Rocilinostat) 是一种选择性HDAC6抑制剂，IC50为 5 nM。它还抑制HDAC1，HDAC2和HDAC3，IC50分别为 58，48 和 51 nM。
T7621	6-Thioinosine 6-Mercaptopurine riboside,6-疏基嘌呤核苷,6TI	Nucleoside Antimetabolite/Analog	Cell Cycle/Checkpoint; DNA Damage/DNA Repair
	6-Thioinosine (6TI) 是一种嘌呤抗代谢物，是抗脂肪形成剂，能降低PPAR γ和C/EBPα及其目标基因 aP2、CD36、LPL 和 LXRα 的 mRNA 水平。
T2512	Mocetinostat MGCD0103,MG0103	Apoptosis; HDAC; Autophagy	Apoptosis; Autophagy; Chromatin/Epigenetic; DNA Damage/DNA Repair
	Mocetinostat (MG0103) 是一种可口服和同种型选择性的HDAC 抑制剂，抑制HDAC1，HDAC2，HDAC3和HDAC11的IC50分别为0.15，0.29，1.66 和 0.59 μM。
T6865	Quisinostat dihydrochloride Quisinostat 2HCl,Quisinostat (JNJ-26481585) 2HCl,JNJ26854165(Quisinostat) 2HCl,JNJ-26481585 2HCl	Apoptosis; HDAC; Autophagy	Apoptosis; Autophagy; Chromatin/Epigenetic; DNA Damage/DNA Repair
	Quisinostat dihydrochloride (JNJ26854165(Quisinostat) 2HCl) 是一种有口服活性，高效的 pan-HDAC 抑制剂，具有广泛的抗肿瘤活性。它对 HDAC1、HDAC2、HDAC4、HDAC10和HDAC11 的IC50值分别为 0.11 nM、0.33 nM、0.64 nM、0.46 nM 和 0.37 nM。
T6233	Entinostat 恩替诺特,SNDX-275,MS-275	Apoptosis; HDAC; Autophagy	Apoptosis; Autophagy; Chromatin/Epigenetic; DNA Damage/DNA Repair
	Entinostat (MS-275) 是一种可口服的 HDAC class I 选择性抑制剂，抑制HDAC1、HDAC2和HDAC3的IC50分别为 243 nM、453 nM 和 248 nM。
T23171	Polyinosinic-polycytidylic acid Poly(I:C),聚胞苷酸	TLR	Immunology/Inflammation
	Polyinosinic-polycytidylic acid (Poly(I:C)) 是一种双链 RNA (dsRNA)，是一种 TLR3 激动剂。Polyinosinic-polycytidylic acid 可以诱导哺乳动物天然免疫。
TNU0187	2',5-Difluoro-2'-deoxy-1-arabinosyluracil 2'-Deoxy-2'-fluoro-5-fluoro-arabinouridine	Nucleoside Antimetabolite/Analog	Cell Cycle/Checkpoint; DNA Damage/DNA Repair
	2',5-Difluoro-2'-deoxy-1-arabinosyluracil (2'-Deoxy-2'-fluoro-5-fluoro-arabinouridine) 是一种尿嘧啶核苷类似物，具有潜在的抗癫痫活性和降压活性，可用于研究抗惊厥和焦虑症。
T17028	Tefinostat CHR-2845	HDAC	Chromatin/Epigenetic; DNA Damage/DNA Repair
	Tefinostat (CHR-2845) 是一种有效的单核细胞/巨噬细胞靶向组蛋白脱乙酰酶 (HDAC) 抑制剂。 Tefinostat 可被胞内酯酶人羧酸酯酶-1 (hCE-1) 裂解成活性酸 CHR-2847。Tefinostat 具有抗肿瘤活性，可用于研究白血病和晚期血液系统恶性肿瘤。
T22869	Inosine-5'-monophosphate (sodium salt hydrate)	Others	Others
	substrate of IMP dehydrogenase (IMPDH)
T75219	5’-O-(4,4’-Dimethoxy trityl)-2’-O-(2-methoxyethyl) inosine	Others	Others
	5’-O-(4,4’-Dimethoxy trityl)-2’-O-(2-methoxyethyl) inosine 是一种具有抗肿瘤活性的嘌呤核苷类似物，主要作用于惰性淋巴系统的恶性肿瘤。其抗癌机制主要通过抑制DNA合成和诱导细胞凋亡（apoptosis）实现。

化合物

Cat.No: T83625

Synonym: 3-bromo-1H-indazole-7-carbonitrile

Target: NOS

Cat.No: T62849

Target: Others

Cat.No: T62987

Target: Others

iNOS inhibitor-10

Cat.No: T72638

Target: NO Synthase

Cat.No: T63261

Target: Others

iNOS/PGE2-IN-1

Cat.No: T63104

Target: Others

Cat.No: T21700

Synonym: 2-Imino-4-methylpiperidine (acetate)

Target: NOS

Cat.No: T19916

Synonym: 1-(2-Trifluoromethylphenyl)imidazole,1-(2-三氟甲基苯基)咪唑

Target: NOS

S-Methylisothiourea sulfate

Cat.No: T22419

Synonym: (S)-Methylisothiourea sulfate,S-甲基异硫脲硫酸盐,S-甲基异硫脲半硫酸盐

Target: NOS, NO Synthase, HSV

Beclometasone dipropionate

Cat.No: T1127

Synonym: Beclovent,Beclomethasone dipropionate,二丙酸倍氯米松,丙酸倍氯米松,Beconase,Vancenase

Target: Glucocorticoid Receptor

N-tert-butyl-α-Phenylnitrone

Cat.No: T23046

Synonym: (Z)-N-benzylidene-2-Methylpropan-2-aMine oxide,N-叔丁基-α-苯基硝酮

Target: ROS, COX

Cat.No: T6055

Synonym: 奎诺司他,JNJ-26481585

Target: Apoptosis, HDAC, Autophagy

Polyinosinic-polycytidylic acid sodium

Cat.No: T12516

Synonym: 双链聚肌胞,Poly(I:C) sodium

Target: Apoptosis, Others, TLR

Resminostat hydrochloride

Cat.No: T4370

Synonym: 4SC-201 hydrochloride,RAS2410 hydrochloride

Target: HDAC

Givinostat hydrochloride

Cat.No: T6279L

Synonym: ITF2357 hydrochloride,Givinostat HCl,ITF2357,ITF 2357,ITF-2357,ITF2357 HCl

Target: HDAC

2′-C-Methyl-6-O-methylinosine

Cat.No: TNU0810

Synonym: 2′-C-Methyl-6-O-methylinosine

Target: Nucleoside Antimetabolite/Analog

Cat.No: T4481

Synonym: HBI-8000,Chidamide,西达本胺,CS 055

Target: HDAC

4-QUinolinecarboxamide, N-[3-[[[2-[4-(aminosulfonyl)phenyl]ethyl]amino]carbonyl]phenyl]-1,2-dihydro-2-oxo-

Cat.No: T9835

Target: Others

Cat.No: T1890

Synonym: SB939

Target: Apoptosis, HDAC

Inosine pranobex

Cat.No: T3614

Synonym: Groprinosin,Isoprinosine,异丙肌苷,Immunovir,Delimmun

Target: IL Receptor, HIV Protease

Nitrobenzylthioinosine

Cat.No: T8551

Synonym: NBMPR,S-(4-硝基苄基)-6-硫代肌苷

Target: AChR, Adenosine Receptor

Cat.No: T8517

Synonym: PX105684,PXD101,贝利司他,PXD-101

Target: HDAC, Autophagy

Cat.No: T1583

Synonym: MK0683,伏立诺他,suberoylanilide hydroxamic acid,SAHA

Target: Apoptosis, Mitophagy, Virus Protease, HDAC, Autophagy

4-Aminosalicylic acid

Cat.No: T1296

Synonym: Aminosalicylic acid,4-aminosalicylate,para-aminosalicylic acid,对氨水杨酸,Aminopar

Target: NF-κB, Lipoxygenase, COX, Glutathione Peroxidase, Antibacterial, Antibiotic

Cat.No: T16729

Synonym: SHP-141

Target: HDAC

Cat.No: T2454

Synonym: NVP-LAQ824,达西司特,LAQ824

Target: HDAC, Autophagy

Givinostat hydrochloride monohydrate

Cat.No: T6279

Synonym: ITF2357,ITF-2357 hydrochloride monohydrate,Givinostat,Gavinostat hydrochloride monohydrate,吉维司他

Target: HDAC

Cat.No: T2078

Synonym: CUDC-907,PI3K/HDAC Inhibitor,CUDC 907

Target: Apoptosis, PI3K, HDAC

Cat.No: T0431

Synonym: CRA 24781,阿贝司他,PCI24781,PCI-24781,PCI 24781,CRA 024781

Target: HDAC

Cat.No: T6362

Synonym: 4SC202,4SC 202,4SC-202 (free base),4SC-202

Target: Apoptosis, HDAC

Cat.No: T27083

Target: Epigenetic Reader Domain, Histone Acetyltransferase, HDAC

Cat.No: T1852

Synonym: NSC726630,PXD101,PX-105684

Target: HDAC

Cat.No: T71138L

Synonym: MDL 73005EF

Target: 5-HT Receptor

Cat.No: T3661

Synonym: ACY241,HDAC-IN-2

Target: HDAC

Cat.No: T2383

Synonym: 帕比司他,NVP-LBH589,LBH589

Target: Apoptosis, HIV Protease, HDAC, Autophagy

Cat.No: T0598

Synonym: 亚氨基芪,Dibenzazepine

Target: Others

Domatinostat tosylate

Cat.No: T4477

Synonym: 4SC-202 tosylate,4SC-202

Target: Apoptosis, HDAC

Sodium 4-aminosalicylate dihydrate

Cat.No: T0020

Synonym: 对氨基水杨酸钠二水合物,Sodium 4-Aminosalicylate,4-Amino-salicylic acid sodium salt

Target: Free radical scavengers, NF-κB, Antibacterial, Antibiotic

Inositol nicotinate

Cat.No: T4509

Synonym: Inositol niacinate,Hexanicotol,Myo-Inositol hexanicotinate,Mesotal,肌醇烟酸酯,Dilexpal,Inositol hexanicotinate

Target: Others

Cat.No: T6481

Synonym: NS 41080,4-(4-氯-2-甲基苯氧基)-N-羟基丁酰胺

Target: Apoptosis, HDAC

Cat.No: T2489

Synonym: ACY-1215,Rocilinostat

Target: Apoptosis, HDAC

Cat.No: T7621

Synonym: 6-Mercaptopurine riboside,6-疏基嘌呤核苷,6TI

Target: Nucleoside Antimetabolite/Analog

Cat.No: T2512

Synonym: MGCD0103,MG0103

Target: Apoptosis, HDAC, Autophagy

Quisinostat dihydrochloride

Cat.No: T6865

Synonym: Quisinostat 2HCl,Quisinostat (JNJ-26481585) 2HCl,JNJ26854165(Quisinostat) 2HCl,JNJ-26481585 2HCl

Target: Apoptosis, HDAC, Autophagy

Cat.No: T6233

Synonym: 恩替诺特,SNDX-275,MS-275

Target: Apoptosis, HDAC, Autophagy

Polyinosinic-polycytidylic acid

Cat.No: T23171

Synonym: Poly(I:C),聚胞苷酸

Target: TLR

2',5-Difluoro-2'-deoxy-1-arabinosyluracil

Cat.No: TNU0187

Synonym: 2'-Deoxy-2'-fluoro-5-fluoro-arabinouridine

Target: Nucleoside Antimetabolite/Analog

Cat.No: T17028

Synonym: CHR-2845

Target: HDAC

Inosine-5'-monophosphate (sodium salt hydrate)

Cat.No: T22869

Target: Others

5’-O-(4,4’-Dimethoxy trityl)-2’-O-(2-methoxyethyl) inosine

Cat.No: T75219

Target: Others

Cat. No.	Product Name	Target	Signaling Pathways
T2738	Dehydroandrographolide	NOS; Influenza Virus	Immunology/Inflammation; Microbiology/Virology
	Dehydroandrographolide 是从草药穿心莲中提取的一种天然产物。它通过使 iNOS 失活来降低 LPS 诱导的急性肺损伤中的氧化应激，有抗感染活性。
T6S1665	Irisflorentin	Others; NO Synthase	Immunology/Inflammation; Others
	Irisflorentin 是天然存在的异黄酮，是大量存在于 Rhizoma Belamcandae 中的活性成分。它明显抑制了诱导型一氧化氮合酶的转录和翻译以及 NO 产生。
TN6951	Ethyl linoleate 亚油酸乙酯	Others	Others
	Ethyl linoleate 对动脉粥样硬化病变的发展和炎症介质的表达有抑制作用。
T6S1572	Sauchinone	ERK; p38 MAPK; NF-κB	MAPK; NF-κB
	Sauchinone 是一种从Saururus chinensis 中获得的非对映异构的木脂素。它通过抑制I-κBα磷酸化和p65核易位来抑制 LPS 诱导的 iNOS，TNF-α 和 COX-2 表达。它具有抗炎和抗氧化活性。
TN2139	Regaloside B 鸦胆子苦醇,王百合苷 B	NOS; COX; NO Synthase	Immunology/Inflammation; Neuroscience
	Regaloside B 是从麝香百合中分离出来的一种苯丙烷，可抑制iNOS 和COX-2的表达，具有抗炎活性。
T0610	Piceatannol 白皮杉醇,trans-Piceatannol,Astringenin	Apoptosis; Serine/threonin kinase; PKA; Syk; PKC; Autophagy	Angiogenesis; Apoptosis; Autophagy; Cell Cycle/Checkpoint; Chromatin/Epigenetic; Cytoskeletal Signaling; Metabolism; Tyrosine Kinase/Adaptors
	Piceatannol (Astringenin) 是一种Syk 抑制剂，可降低由 TNF 诱导的 iNOS 表达，可研究急性肺损伤。它是存在于各种水果和蔬菜中天然存在的多酚二苯乙烯，可诱导细胞自噬和凋亡，具有抗癌和抗炎特性。
T5S0045	Isofraxidin 6,8-Dimethoxyumbelliferone,异秦皮啶,Phytodolor,异嗪皮啶	MMP; ERK; p38 MAPK; TLR; COX	Immunology/Inflammation; MAPK; Neuroscience; Proteases/Proteasome
	Isofraxidin (Phytodolor) 是来自刺五加的香豆素成分，抑制MMP-7表达和人肝癌细胞侵袭。它作用于肝癌细胞，抑制ERK1/2磷酸化。它减弱iNOS 和COX-2表达，还抑制TLR4/髓样分化蛋白 2 复合物的形成。
T1079	Metronidazole Flagyl,Metronidazol,甲硝唑,Anagiardil	Apoptosis; NADPH; Hydrogenase; Antibacterial; Antibiotic; Parasite; Antifection	Apoptosis; Metabolism; Microbiology/Virology
	Metronidazole (Metronidazol) 是一种合成的硝基咪唑衍生物，一种抗生素和抗原虫剂，具有口服活性和血脑屏障渗透性。Metronidazole 可用于治疗或预防厌氧菌引起的系统或局部感染。
TCS2170	2,5-Dihydroxyacetophenone Quinacetophenone,2-Acetylhydroquinone,2-5-dihydroxyacetophenone,2 '，5'-二羟基苯乙酮,Acetylhydroquinone,2,5-二羟基苯乙酮,DHAP	ERK; NF-κB; Tyrosinase	MAPK; NF-κB; Proteases/Proteasome
	2,5-Dihydroxyacetophenone (Quinacetophenone) 是从熟地黄中分离出的一种天然产物，通过阻断 ERK1/2和 NF-κB 信号通路，抑制活化巨噬细胞中炎症介质的产生。
TN1109	3-O-Acetyl-16α-hydroxydehydrotrametenolic acid 3-O-Acetyl-16 alpha-hydroxydehydrotrametenolic acid,3-O-乙酰基-16Α-羟基松苓新酸	NOS; NO Synthase; Prostaglandin Receptor	GPCR/G Protein; Immunology/Inflammation
	3-O-Acetyl-16α-hydroxydehydrotrametenolic acid (3-O-Acetyl-16 alpha-hydroxydehydrotrametenolic acid) 是三萜类化合物。它能够作用于 LPS 刺激的 Raw264.7 细胞，减少NO 产生和 iNOS 表达，具有消炎作用。
TN1836	Kudinoside D	LDL; AMPK; PPAR	Chromatin/Epigenetic; DNA Damage/DNA Repair; Metabolism; PI3K/Akt/mTOR signaling
	Kudinoside D 是 Ilex kudingcha 中三萜皂苷的主要天然成分之一。它能够调节 3T3-L1 脂肪细胞中 AMPK 途径，并可抑制脂肪形成。
TMS1830	Disodium 5'-inosinate Disodium Inosinate,肌苷酸二钠盐,Sodium Inosinate,5'-IMP disodium salt	Others	Others
	Disodium 5'-inosinate (5'-IMP disodium salt) 是一种食品添加剂，可从通过糖的细菌发酵获得。
T6S2227	Spinosin 斯皮诺素,Flavoayamenin	Others	Others
	Spinosin (Flavoayamenin) 是一种具有神经保护作用的 C-糖苷类黄酮，从 Zizyphus jujube 种子分离得到，能够激活 Nrf2/HO-1 通路，并抑制 Aβ1-42的产生和聚合。
T5796	Plantainoside D Isoplantamajoside,车前草苷D	RAAS; PKC	Chromatin/Epigenetic; Cytoskeletal Signaling; Endocrinology/Hormones
	Plantainoside D (Isoplantamajoside) 可以抑制 ACE ，IC50=2.17 mM。Plantainoside D 也是IKK-β抑制剂。
T4897	Inosine-5'-triphosphate trisodium salt ITP,肌苷-5'-三磷酸三钠盐,三磷酸肌苷三钠盐,Inosine 5'-triphosphate trisodium salt	Others; Endogenous Metabolite	Metabolism; Others
	Inosine-5'-triphosphate trisodium salt (ITP) 是三磷酸核苷，能够作为 ATPases 和 GTPases 的底物。
T21495	Spinosyn A	Others	Others
	Spinosyn A 是聚酮化合物衍生的大环内酯，来自多刺甘蔗多孢菌。Spinosyn A 是有效的杀虫剂。
T3S0309	D(+)-Raffinose pentahydrate D-Raffinose pentahydrate,Raffinose,D(+)-五水棉子糖,五水棉子糖	Others; Endogenous Metabolite	Metabolism; Others
	D(+)-Raffinose pentahydrate (D-Raffinose pentahydrate) 是果糖，半乳糖和葡萄糖组成的三糖，天然存在于各种蔬菜和谷物中。D(+)-Raffinose pentahydrate 是一种功能性低聚糖。
TN3861	Dihydropinosylvin 山药	Anti-infection	Microbiology/Virology
	Dihydropinosylvin 是一种植物抗毒素，对枝孢枝孢菌、Botryodiplodia theobromae、黑曲霉和石化青霉具有抗真菌活性，对蜡状芽孢杆菌、金黄色葡萄球菌、铜绿假单胞菌和大肠杆菌也有很强的抗菌活性。双色高粱幼苗的种子和根伸长。
TN6745	PALATINOSE TNP-470,帕拉金糖水合物,Isomaltulose	Others	Others
	PALATINOSE (TNP-470) 是一种天然存在的二糖，由α-1,6-连接的葡萄糖和果糖组成。PALATINOSE 对肝脏代谢功能具有有益的影响，因此可能是蔗糖甜味剂的良好替代品。
T3755	Pinostilbene	Others	Others
	Pinostilbene 是一种 Pterostilbene 的主要代谢物，能够抑制结肠癌细胞。
T1709	2'-Deoxyinosine Guanine deoxyriboside,Deoxyinosine,2'-脱氧肌苷	Others; Endogenous Metabolite	Metabolism; Others
	2'-Deoxyinosine (Guanine deoxyriboside) 具有抑制人癌细胞株生长的活性，并发现其与嘌呤核苷磷酸化酶缺乏有关。
TN1808	Isovitexin 2''-O-arabinoside	Others	Others
	Isovitexin 2''-O-arabinoside 是一种在紫花苜蓿植物中发现黄酮类化合物。
T3843	Pinosylvin 银松素,3,5-stilbenediol,5-Styrylresorcinol	Apoptosis; Others; Antibacterial; Autophagy	Apoptosis; Autophagy; Microbiology/Virology; Others
	Pinosylvin (5-Styrylresorcinol) 是从Pinus spp 的心材中分离出来的一种白藜芦醇类似物，可诱导白血病细胞凋亡和自噬。它是一种感染前的类苯乙烯类毒素，具有抗菌活性。
T5S2228	6‴-Feruloylspinosin 6'''-Feruloylspinosin,6-阿魏酰斯皮诺素	NF-κB	NF-κB
	6‴-Feruloylspinosin (6'''-Feruloylspinosin) 是一种类黄酮，分离自 Ziziphus jujuba 种子中。在大鼠海马神经元中，它能透过血脑屏障，增强 GABAAα1、GABAAα5、GABABR1 的 mRNA 表达。
T2S0112	yibeinoside A 伊贝碱苷A,Sinpeinine-3-O-β-glucoside	Others	Others
	Yibeinoside A (Sinpeinine-3-O-β-glucoside) 是一种生物碱，分离自西贝母中。
TN6910	Aloinoside B 11-o-Rhamnosylaloin B
	Aloinoside B (11-o-Rhamnosylaloin B) 是一种来自芦荟的糖苷。
T67867	Mycaminosyltylonolide	Antibacterial	Microbiology/Virology
	Mycaminosyltylonolide 是一种大环内酯类抗生素，它是 tyololide 在位置5上具有β - d -mycaminosyl 残基。Mycaminosyltylonolide 是一种有效的抗生素，具有抗菌活性和抑制荧光素酶的合成。
T5915	D-chiro-Inositol D-手性肌醇,D-(+)-CHIRO-INOSITOL	Endogenous Metabolite	Metabolism
	D-chiro-Inositol (D-(+)-CHIRO-INOSITOL) 是肌醇差向异构体，存在于某些哺乳动物糖基磷脂酰肌醇蛋白锚和具有胰岛素样生物特性的肌醇磷脂聚糖中。它能够抑制高血糖，改善胰岛素抵抗。它用于多囊卵巢综合征和糖尿病的相关研究。
TN2082	Pinostrobin	Beta Amyloid; IL Receptor; Serine/threonin kinase; TNF	Apoptosis; Cell Cycle/Checkpoint; Immunology/Inflammation; Metabolism; Neuroscience
	Pinostrobin 是一种 PCSK9抑制剂，可抑制 PCSK9 的催化活性。它是能够在多种植物中发现的黄酮类化合物，并具有抗氧化，抗炎，抗癌和神经保护作用。它是有前景的胆固醇调节和脂质管理剂。
T2S0461	D-Arabinose	Others; Endogenous Metabolite	Metabolism; Others
	D-arabinose 是内源性代谢产物的一种。
T19083	1-Methylinosine N1-Methylinosine,Inosine, 1-methyl,1-甲基肌苷	Nucleoside Antimetabolite/Analog; Endogenous Metabolite	Cell Cycle/Checkpoint; DNA Damage/DNA Repair; Metabolism
	1-Methylinosine (N1-Methylinosine) 是在真核生物 tRNA 反密码子 3' 位 tRNA 的 37 位上发现的修饰核苷酸，具有代谢物的作用。
TN2083	Pinostrobin chalcone 球松素查尔酮,2',3'-二羟基-4'-甲氧基查耳酮
	Pinostrobin chalcone 是一种从豆科植物木豆中分离出的查尔酮类化合物，具有抗癌活性，对 MDA-MB-231 的 IC50 值为 20.42±2.23μg/mL，对 HT-29 结肠癌细胞株的IC50 值为 22.51±0.42 μg/mL。
T0437	Inosine INO 495,NSC 20262,肌苷	ROS; Endogenous Metabolite; Adenosine Receptor	GPCR/G Protein; Immunology/Inflammation; Metabolism; Neuroscience
	Inosine (NSC-20262) 是由腺苷分解代谢产生的一种内源性嘌呤核苷，是腺苷受体A1R 和A2AR 的激动剂，具有抗炎免疫调节，抗伤害和神经保护作用。
T13752	L-(+)-Arabinose	Endogenous Metabolite	Metabolism
	L-(+)-Arabinose 能够选择性抑制肠道蔗糖酶，并抑制因蔗糖摄入而导致的血浆葡萄糖提高。
T0588	D-(-)-Arabinose D-阿拉伯糖,D(-)-Arabinose,D-arabinose	Others	Others
	D-(-)-Arabinose 是一种单糖，对秀丽隐杆线虫有较强的生长抑制作用(IC50:7.5 mM)。
T8144	Raffinose Melitose,Melitriose,棉子糖	Others; Endogenous Metabolite	Metabolism; Others
	Raffinose (Melitriose) 是不能够消化的短链寡糖，是由半乳糖，葡萄糖和果糖组成的三糖，能够在许多植物中找到。它能够被 α-半乳糖苷酶 (α-GAL) 水解为 D-半乳糖和蔗糖。
T0646	5-Aminosalicylic Acid Mesalazine,5-ASA,5-氨基水杨酸,Mesalamine	NF-κB; Lipoxygenase; COX; Glutathione Peroxidase; Endogenous Metabolite; PAK; PPAR	Cytoskeletal Signaling; DNA Damage/DNA Repair; Immunology/Inflammation; Metabolism; Neuroscience; NF-κB
	5-Aminosalicylic Acid (5-ASA) 是一种特异性的PPARγ激动剂，还抑制 p21-激活激酶1(PAK1) 和NF-κB，具有抗炎活性。
T9076	Spinosad	Others	Others
	Spinosad 是在土壤细菌 S. spinosa 中发现的一种杀虫剂，是大环内酯多杀菌素 A 和多杀菌素 D 的混合物，可作为昆虫烟碱乙酰胆碱酯酶受体 (nAChRs) 的激动剂。它具有优良的环境和哺乳动物毒理学特征，以及杀灭幼虫的活性。
T4685	INOSINIC ACID Inosine 5′-monophosphate,IMP,5'-肌苷酸,I-5'-P	Endogenous Metabolite	Metabolism
	Inosinic acid (IMP) 是内源性代谢产物。
T8012	Scyllo-Inositol Scyllitol,鲨肌醇	Beta Amyloid; Endogenous Metabolite	Metabolism; Neuroscience
	Scyllo-Inositol (Scyllitol) 是淀粉样抑制剂，能够抑制 α-突触核蛋白聚集。它在体外能够稳定非纤维状无毒形式的淀粉样蛋白-β 肽，逆转阿尔茨海默病小鼠模型的认知缺陷，抑制突触毒性和淀粉样斑块。
T5S1679	Acetylshengmanol Arabinoside 乙酰升麻醇-3-O-α-L-阿拉伯糖苷,Acetylcimigenol 3-O-alpha-L-arabinopyran	Others	Others
	Acetylcimigenol 3-O-alpha-L-arabinopyran 是一种升麻提取物。
T4818	Thyminose 2-脱氧-D-核糖,2-Deoxy-D-ribose,2-Deoxy-D-arabinose,2-Deoxy-D-erythropentose	Apoptosis; Others; Endogenous Metabolite	Apoptosis; Metabolism; Others
	Thyminose 通过抑制谷胱甘肽的合成和增加其外排诱导细胞凋亡。
T0421	i-Inositol Inositol,myo-Inositol,肌醇,meso-Inositol	Endogenous Metabolite	Metabolism
	i-Inositol (myo-Inositol) 是一种细胞内磷酸化合物，参与细胞信号传导，可能刺激肿瘤细胞分化。
T7523	Guanidinosuccinic acid 2-胍基琥珀酸,胍基琥珀酸	Others; Endogenous Metabolite	Metabolism; Others
	Guanidinosuccinic acid 是一种含氮代谢物，在尿毒症患者的血清和尿液中水平升高。
T4882	Arabinose DL-阿拉伯糖,DL-Arabinose,阿拉伯糖	Others; Endogenous Metabolite	Metabolism; Others
	Arabinose (DL-Arabinose)，也被称为(+/-)-阿拉伯糖或芦荟糖。Arabinose 主要在粪便中检测到。在细胞内，Arabinose 主要位于细胞质中。Arabinose 存在于从酵母到人类的所有真核生物中。
T4875	Palatinose hydrate 6-O-α-D-Glucopyranosyl-D-fructose, Isoma,帕拉金糖水合物	Others; Endogenous Metabolite	Metabolism; Others
	Palatinose hydrate (6-O-α-D-Glucopyranosyl-D-fructose, Isoma) 是内源性代谢产物的一种。
T5073	Inosine 5'-monophosphate disodium salt hydrate Inosine 5'-monophosphate disodium salt,5'-IMP-Na2,肌苷5-单磷酸二钠盐水合物,Disodium 5'-inosinate monohydrate	Others; Endogenous Metabolite	Metabolism; Others
	Inosine 5'-monophosphate disodium salt hydrate (Inosine 5'-monophosphate disodium salt) 或肌苷酸是次黄嘌呤的核糖核苷酸，是嘌呤合成过程中形成的第一个核苷酸。
TN1488	Chrysin 6-C-glucoside 8-C-arabinoside	Others	Others
	Chrysin 6-C-glucoside 8-C-arabinoside 是α±-葡萄糖苷酶抑制剂，α±-葡萄糖苷酶抑制剂广泛用于2型糖尿病的治疗。
TN1487	Chrysin 6-C-arabinoside 8-C-glucoside	Others	Others
	Chrysin 6-C-arabinoside 8-C-glucoside 是α±-葡萄糖苷酶抑制剂，α±-葡萄糖苷酶抑制剂广泛用于2型糖尿病的治疗。
TN4033	Eugenol rutinoside	Others	Others
	Eugenol rutinoside 是一种存在于dendropanax dentiger 中的天然产物。
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天然产物

Dehydroandrographolide

Cat.No: T2738

Target: NOS, Influenza Virus

Cat.No: T6S1665

Target: Others, NO Synthase

Ethyl linoleate

Cat.No: TN6951

Synonym: 亚油酸乙酯

Target: Others

Cat.No: T6S1572

Target: ERK, p38 MAPK, NF-κB

Cat.No: TN2139

Synonym: 鸦胆子苦醇,王百合苷 B

Target: NOS, COX, NO Synthase

Cat.No: T0610

Synonym: 白皮杉醇,trans-Piceatannol,Astringenin

Target: Apoptosis, Serine/threonin kinase, PKA, Syk, PKC, Autophagy

Cat.No: T5S0045

Synonym: 6,8-Dimethoxyumbelliferone,异秦皮啶,Phytodolor,异嗪皮啶

Target: MMP, ERK, p38 MAPK, TLR, COX

Cat.No: T1079

Synonym: Flagyl,Metronidazol,甲硝唑,Anagiardil

Target: Apoptosis, NADPH, Hydrogenase, Antibacterial, Antibiotic, Parasite, Antifection

2,5-Dihydroxyacetophenone

Cat.No: TCS2170

Synonym: Quinacetophenone,2-Acetylhydroquinone,2-5-dihydroxyacetophenone,2 '，5'-二羟基苯乙酮,Acetylhydroquinone,2,5-二羟基苯乙酮,DHAP

Target: ERK, NF-κB, Tyrosinase

3-O-Acetyl-16α-hydroxydehydrotrametenolic acid

Cat.No: TN1109

Synonym: 3-O-Acetyl-16 alpha-hydroxydehydrotrametenolic acid,3-O-乙酰基-16Α-羟基松苓新酸

Target: NOS, NO Synthase, Prostaglandin Receptor

Cat.No: TN1836

Target: LDL, AMPK, PPAR

Disodium 5'-inosinate

Cat.No: TMS1830

Synonym: Disodium Inosinate,肌苷酸二钠盐,Sodium Inosinate,5'-IMP disodium salt

Target: Others

Cat.No: T6S2227

Synonym: 斯皮诺素,Flavoayamenin

Target: Others

Plantainoside D

Cat.No: T5796

Synonym: Isoplantamajoside,车前草苷D

Target: RAAS, PKC

Inosine-5'-triphosphate trisodium salt

Cat.No: T4897

Synonym: ITP,肌苷-5'-三磷酸三钠盐,三磷酸肌苷三钠盐,Inosine 5'-triphosphate trisodium salt

Target: Others, Endogenous Metabolite

Cat.No: T21495

Target: Others

D(+)-Raffinose pentahydrate

Cat.No: T3S0309

Synonym: D-Raffinose pentahydrate,Raffinose,D(+)-五水棉子糖,五水棉子糖

Target: Others, Endogenous Metabolite

Dihydropinosylvin

Cat.No: TN3861

Synonym: 山药

Target: Anti-infection

Cat.No: TN6745

Synonym: TNP-470,帕拉金糖水合物,Isomaltulose

Target: Others

Cat.No: T3755

Target: Others

2'-Deoxyinosine

Cat.No: T1709

Synonym: Guanine deoxyriboside,Deoxyinosine,2'-脱氧肌苷

Target: Others, Endogenous Metabolite

Isovitexin 2''-O-arabinoside

Cat.No: TN1808

Target: Others

Cat.No: T3843

Synonym: 银松素,3,5-stilbenediol,5-Styrylresorcinol

Target: Apoptosis, Others, Antibacterial, Autophagy

6‴-Feruloylspinosin

Cat.No: T5S2228

Synonym: 6'''-Feruloylspinosin,6-阿魏酰斯皮诺素

Target: NF-κB

Cat.No: T2S0112

Synonym: 伊贝碱苷A,Sinpeinine-3-O-β-glucoside

Target: Others

Cat.No: TN6910

Synonym: 11-o-Rhamnosylaloin B

Mycaminosyltylonolide

Cat.No: T67867

Target: Antibacterial

D-chiro-Inositol

Cat.No: T5915

Synonym: D-手性肌醇,D-(+)-CHIRO-INOSITOL

Target: Endogenous Metabolite

Cat.No: TN2082

Target: Beta Amyloid, IL Receptor, Serine/threonin kinase, TNF

Cat.No: T2S0461

Target: Others, Endogenous Metabolite

1-Methylinosine

Cat.No: T19083

Synonym: N1-Methylinosine,Inosine, 1-methyl,1-甲基肌苷

Target: Nucleoside Antimetabolite/Analog, Endogenous Metabolite

Pinostrobin chalcone

Cat.No: TN2083

Synonym: 球松素查尔酮,2',3'-二羟基-4'-甲氧基查耳酮

Cat.No: T0437

Synonym: INO 495,NSC 20262,肌苷

Target: ROS, Endogenous Metabolite, Adenosine Receptor

L-(+)-Arabinose

Cat.No: T13752

Target: Endogenous Metabolite

D-(-)-Arabinose

Cat.No: T0588

Synonym: D-阿拉伯糖,D(-)-Arabinose,D-arabinose

Target: Others

Cat.No: T8144

Synonym: Melitose,Melitriose,棉子糖

Target: Others, Endogenous Metabolite

5-Aminosalicylic Acid

Cat.No: T0646

Synonym: Mesalazine,5-ASA,5-氨基水杨酸,Mesalamine

Target: NF-κB, Lipoxygenase, COX, Glutathione Peroxidase, Endogenous Metabolite, PAK, PPAR

Cat.No: T9076

Target: Others

INOSINIC ACID

Cat.No: T4685

Synonym: Inosine 5′-monophosphate,IMP,5'-肌苷酸,I-5'-P

Target: Endogenous Metabolite

Scyllo-Inositol

Cat.No: T8012

Synonym: Scyllitol,鲨肌醇

Target: Beta Amyloid, Endogenous Metabolite

Acetylshengmanol Arabinoside

Cat.No: T5S1679

Synonym: 乙酰升麻醇-3-O-α-L-阿拉伯糖苷,Acetylcimigenol 3-O-alpha-L-arabinopyran

Target: Others

Cat.No: T4818

Synonym: 2-脱氧-D-核糖,2-Deoxy-D-ribose,2-Deoxy-D-arabinose,2-Deoxy-D-erythropentose

Target: Apoptosis, Others, Endogenous Metabolite

Cat.No: T0421

Synonym: Inositol,myo-Inositol,肌醇,meso-Inositol

Target: Endogenous Metabolite

Guanidinosuccinic acid

Cat.No: T7523

Synonym: 2-胍基琥珀酸,胍基琥珀酸

Target: Others, Endogenous Metabolite

Cat.No: T4882

Synonym: DL-阿拉伯糖,DL-Arabinose,阿拉伯糖

Target: Others, Endogenous Metabolite

Palatinose hydrate

Cat.No: T4875

Synonym: 6-O-α-D-Glucopyranosyl-D-fructose, Isoma,帕拉金糖水合物

Target: Others, Endogenous Metabolite

Inosine 5'-monophosphate disodium salt hydrate

Cat.No: T5073

Synonym: Inosine 5'-monophosphate disodium salt,5'-IMP-Na2,肌苷5-单磷酸二钠盐水合物,Disodium 5'-inosinate monohydrate

Target: Others, Endogenous Metabolite

Chrysin 6-C-glucoside 8-C-arabinoside

Cat.No: TN1488

Target: Others

Chrysin 6-C-arabinoside 8-C-glucoside

Cat.No: TN1487

Target: Others

Eugenol rutinoside

Cat.No: TN4033

Target: Others

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Species：

Expression System：

Tag：

Cat. No.	Product Name	Species	Expression System
TMPH-03164	Beta-lactamase OXA-10 Protein, Pseudomonas aeruginosa, Recombinant (His & SUMO) Beta-lactamase OXA-10,bla,Beta-lactamase PSE-2,oxa10,pse2	Pseudomonas aeruginosa	E. coli
	Hydrolyzes both carbenicillin and oxacillin. Beta-lactamase OXA-10 Protein, Pseudomonas aeruginosa, Recombinant (His & SUMO) is expressed in E. coli expression system with N-6xHis-SUMO tag. The predicted molecular weight is 43.5 kDa and the accession number is P14489.
TMPH-03177	RhlR Protein, Pseudomonas aeruginosa, Recombinant (His & Myc & SUMO) Elastase modulator,rhlR,Regulatory protein RhlR,HTH-type quo...	Pseudomonas aeruginosa	E. coli
	Necessary for transcriptional activation of the rhlAB genes encoding the rhamnosyltransferase. It also functions as a transcriptional activator of elastase structural gene (lasB). Binds to autoinducer molecules BHL (N-butanoyl-L-homoserine lactone), and HHL (N-hexanoyl-L-homoserine lactone). RhlR Protein, Pseudomonas aeruginosa, Recombinant (His & Myc & SUMO) is expressed in E. coli expression system with N-10xHis-SUMO and C-Myc tag. The predicted molecular weight is 47.6 kDa and the accession n...
TMPY-03172	Argininosuccinate lyase Protein, Human, Recombinant (His & GST) ASAL,argininosuccinate lyase,ASL	Human	Baculovirus Insect Cells
	The recycling of citrulline by argininosuccinate synthase 1 (ASS1) and argininosuccinate lyase (ASL) is crucial to maintain arginine availability and nitric oxide (NO) production. Nitric oxide (NO) plays an established role in numerous physiological and pathological processes, but the specific cellular sources of NO in disease pathogenesis remain unclear, preventing the implementation of NO-related therapy. Argininosuccinate lyase (ASL) is the only enzyme able to produce arginine, the substrate ...
TMPH-00046	Aln g I Protein, Alnus glutinosa, Recombinant (Yeast, His) Major pollen allergen Aln g 1,Allergen Aln g I,Aln g 1	European alder	P. pastoris (Yeast)
	Aln g I Protein, Alnus glutinosa, Recombinant (Yeast, His) is expressed in yeast with N-6xHis tag. The predicted molecular weight is 19.2 kDa and the accession number is P38948.
TMPH-03176	LasA Protein, Pseudomonas aeruginosa, Recombinant (His & SUMO) lasA,Staphylolytic protease,Protease LasA	Pseudomonas aeruginosa	E. coli
	LasA Protein, Pseudomonas aeruginosa, Recombinant (His & SUMO) is expressed in E. coli expression system with N-6xHis-SUMO tag. The predicted molecular weight is 36.0 kDa and the accession number is P14789.
TMPH-00346	Limulus clotting factor C Protein, Carcinoscorpius rotundicauda, Recombinant (His) Limulus clotting factor C	Carcinoscorpius rotundicauda	E. coli
	This enzyme is closely associated with an endotoxin-sensitive hemolymph coagulation system which may play important roles in both hemostasis and host defense mechanisms. Its active form catalyzes the activation of factor B. Limulus clotting factor C Protein, Carcinoscorpius rotundicauda, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 42.2 kDa and the accession number is Q26422.
TMPH-03168	Exotoxin A Protein, Pseudomonas aeruginosa, Recombinant (His & KSI) NAD(+)--diphthamide ADP-ribosyltransferase,Exotoxin A,eta,Ps...	Pseudomonas aeruginosa	E. coli
	An NAD-dependent ADP-ribosyltransferase (ADPRT). Catalyzes the transfer of the ADP ribosyl moiety of oxidized NAD (NAD(+)) onto eukaryotic elongation factor 2 (eEF-2) thus arresting protein synthesis. Has an LD(50) of 65 ng/ml against the human lung epithelial cell line C38. Exotoxin A Protein, Pseudomonas aeruginosa, Recombinant (His & KSI) is expressed in E. coli expression system with N-6xHis-KSI tag. The predicted molecular weight is 39.9 kDa and the accession number is P11439.
TMPH-03175	Porin P Protein, Pseudomonas aeruginosa, Recombinant (His & SUMO) Outer membrane protein D1,oprP,Porin P	Pseudomonas aeruginosa	E. coli
	Anion specific, the binding site has higher affinity for phosphate than chloride ions. Porin O has a higher affinity for polyphosphates (tripolyphosphate and pyrophosphate) while porin P has a higher affinity for orthophosphate. Porin P Protein, Pseudomonas aeruginosa, Recombinant (His & SUMO) is expressed in E. coli expression system with N-6xHis-SUMO tag. The predicted molecular weight is 61.2 kDa and the accession number is P05695.
TMPH-03169	PLC-H Protein, Pseudomonas aeruginosa, Recombinant (His & Myc & SUMO) Phosphatidylcholine cholinephosphohydrolase,Hemolytic phosph...	Pseudomonas aeruginosa	E. coli
	Hydrolyzes sphingomyelin in addition to phosphatidylcholine. PLC-H Protein, Pseudomonas aeruginosa, Recombinant (His & Myc & SUMO) is expressed in E. coli expression system with N-10xHis-SUMO and C-Myc tag. The predicted molecular weight is 64.3 kDa and the accession number is P06200.
TMPH-00167	L-arabinose isomerase Protein, Bacillus subtilis, Recombinant (His & Myc) L-arabinose isomerase,araA	Bacillus subtilis	E. coli
	Catalyzes the conversion of L-arabinose to L-ribulose. L-arabinose isomerase Protein, Bacillus subtilis, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 63.6 kDa and the accession number is P94523.
TMPH-03180	LpxC Protein, Pseudomonas aeruginosa, Recombinant (His & SUMO) UDP-3-O-acyl-N-acetylglucosamine deacetylase,lpxC,UDP-3-O-[R...	Pseudomonas aeruginosa	E. coli
	Catalyzes the hydrolysis of UDP-3-O-myristoyl-N-acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis. LpxC Protein, Pseudomonas aeruginosa, Recombinant (His & SUMO) is expressed in E. coli expression system with N-6xHis-SUMO tag. The predicted molecular weight is 49.4 kDa and the accession number is P47205.
TMPH-03174	LecA Protein, Pseudomonas aeruginosa, Recombinant (His) lecA,PA-I galactophilic lectin,Galactose-binding lectin	Pseudomonas aeruginosa	E. coli
	D-galactose specific lectin. Binds in decreasing order of affinity: melibiose, methyl-alpha-D-galactoside, D-galactose, methyl-beta-D-galactoside, N-acetyl-D-galactosamine. Similar to plant lectins in its selective (carbohydrate-specific) hemagglutinating activity. LecA Protein, Pseudomonas aeruginosa, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 16.8 kDa and the accession number is Q05097.
TMPH-02034	Retinoschisin Protein, Human, Recombinant (His) Retinoschisin,X-linked juvenile retinoschi...	Human	E. coli
	Retinoschisin Protein, Human, Recombinant (His) is expressed in E. coli.
TMPH-03173	OprF Protein, Pseudomonas aeruginosa, Recombinant (His) Outer membrane porin F,oprF	Pseudomonas aeruginosa	E. coli
	Has porin activity, forming small water-filled channels. Also has a structural role in determining cell shape and ability to grow in low-osmolarity medium. OprF Protein, Pseudomonas aeruginosa, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 39.3 kDa and the accession number is P13794.
TMPH-03171	Lysyl endopeptidase Protein, Pseudomonas aeruginosa, Recombinant (His & SUMO) Lysyl endopeptidase,prpL,PvdS-regulated endoprotease,Proteas...	Pseudomonas aeruginosa	E. coli
	Lysine-specific endoprotease. Involved in corneal virulence. Lysyl endopeptidase Protein, Pseudomonas aeruginosa, Recombinant (His & SUMO) is expressed in E. coli expression system with N-6xHis-SUMO tag. The predicted molecular weight is 42.4 kDa and the accession number is Q9HWK6.
TMPH-03407	NIFH Protein, Rhizobium leguminosarum, Recombinant (GST & His & Myc) Nitrogenase iron protein,Nitrogenase reductase,Nitrogenase c...	Rhizobium leguminosarum	E. coli
	The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex, which has 2 components: the iron protein and the molybdenum-iron protein. NIFH Protein, Rhizobium leguminosarum, Recombinant (GST & His & Myc) is expressed in E. coli expression system with N-10xHis-GST and C-Myc tag. The predicted molecular weight is 35.0 kDa and the accession number is P20623.
TMPH-03170	PvdA Protein, Pseudomonas aeruginosa, Recombinant (His & SUMO) Pyoverdin biosynthesis protein A,L-ornithine N(5)-hydroxylas...	Pseudomonas aeruginosa	E. coli
	PvdA Protein, Pseudomonas aeruginosa, Recombinant (His & SUMO) is expressed in E. coli expression system with N-6xHis-SUMO tag. The predicted molecular weight is 65.5 kDa and the accession number is Q51548.
TMPH-00045	Aln g I Protein, Alnus glutinosa, Recombinant (E. coli, His) Allergen Aln g I,Aln g 1,Major pollen allergen Aln g 1	Alnus glutinosa	E. coli
	Aln g I Protein, Alnus glutinosa, Recombinant (E. coli, His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 21.2 kDa and the accession number is P38948.
TMPH-03172	OprI Protein, Pseudomonas aeruginosa, Recombinant (His) Major outer membrane lipoprotein,oprI	Pseudomonas aeruginosa	E. coli
	OprI Protein, Pseudomonas aeruginosa, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 12.9 kDa and the accession number is P11221.
TMPH-03166	Elastase Protein, Pseudomonas aeruginosa, Recombinant (His & SUMO) PAE,lasB,Pseudolysin,Neutral metalloproteinase,Elastase	Pseudomonas aeruginosa	E. coli
	Cleaves host elastin, collagen, IgG, and several complement components as well as endogenous pro-aminopeptidase. Autocatalyses processing of its pro-peptide. Processes the pro-peptide of pro-chitin-binding protein (cbpD). Involved in the pathogenesis of P.aeruginosa infections. Elastase Protein, Pseudomonas aeruginosa, Recombinant (His & SUMO) is expressed in E. coli expression system with N-6xHis-SUMO tag. The predicted molecular weight is 49.1 kDa and the accession number is P14756.
TMPH-03165	Beta-lactamase Protein, Pseudomonas aeruginosa, Recombinant (His & SUMO) Beta-lactamase,ampC,ampA,Cephalosporinase	Pseudomonas aeruginosa	E. coli
	Beta-lactamase Protein, Pseudomonas aeruginosa, Recombinant (His & SUMO) is expressed in E. coli expression system with N-6xHis-SUMO tag. The predicted molecular weight is 56.7 kDa and the accession number is P24735.
TMPH-03179	LpxC Protein, Pseudomonas aeruginosa, Recombinant (His & Myc & SUMO) UDP-3-O-[R-3-hydroxymyristoyl]-N-acetylglucosamine deacetyla...	Pseudomonas aeruginosa	E. coli
	Catalyzes the hydrolysis of UDP-3-O-myristoyl-N-acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis. LpxC Protein, Pseudomonas aeruginosa, Recombinant (His & Myc & SUMO) is expressed in E. coli expression system with N-10xHis-SUMO and C-Myc tag. The predicted molecular weight is 53.4 kDa and the accession number is A6VB79.
TMPH-03178	TusA Protein, Pseudomonas aeruginosa, Recombinant (His & SUMO) tusA,Sulfur carrier protein TusA	Pseudomonas aeruginosa	E. coli
	Sulfur carrier protein which probably makes part of a sulfur-relay system. TusA Protein, Pseudomonas aeruginosa, Recombinant (His & SUMO) is expressed in E. coli expression system with N-6xHis-SUMO tag. The predicted molecular weight is 21.8 kDa and the accession number is Q9I3F3.
TMPH-03167	toxR Protein, Pseudomonas aeruginosa, Recombinant (His) toxR,Exotoxin A regulatory protein	Pseudomonas aeruginosa	E. coli
	Positive regulation of toxA gene transcription. toxR Protein, Pseudomonas aeruginosa, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 32.9 kDa and the accession number is P09852.
TMPH-01552	IRF1 Protein, Human, Recombinant (GST & His) IRF1,Interferon regulatory factor 1	Human	Baculovirus Insect Cells
	Transcriptional regulator which displays a remarkable functional diversity in the regulation of cellular responses. Regulates transcription of IFN and IFN-inducible genes, host response to viral and bacterial infections, regulation of many genes expressed during hematopoiesis, inflammation, immune responses and cell proliferation and differentiation, regulation of the cell cycle and induction of growth arrest and programmed cell death following DNA damage. Stimulates both innate and acquired imm...

重组蛋白

Beta-lactamase OXA-10 Protein, Pseudomonas aeruginosa, Recombinant (His & SUMO)

Cat.No: TMPH-03164

Species: Pseudomonas aeruginosa

Expression System: E. coli

RhlR Protein, Pseudomonas aeruginosa, Recombinant (His & Myc & SUMO)

Cat.No: TMPH-03177

Species: Pseudomonas aeruginosa

Expression System: E. coli

Argininosuccinate lyase Protein, Human, Recombinant (His & GST)

Cat.No: TMPY-03172

Species: Human

Expression System: Baculovirus Insect Cells

Aln g I Protein, Alnus glutinosa, Recombinant (Yeast, His)

Cat.No: TMPH-00046

Species: European alder

Expression System: P. pastoris (Yeast)

LasA Protein, Pseudomonas aeruginosa, Recombinant (His & SUMO)

Cat.No: TMPH-03176

Species: Pseudomonas aeruginosa

Expression System: E. coli

Limulus clotting factor C Protein, Carcinoscorpius rotundicauda, Recombinant (His)

Cat.No: TMPH-00346

Species: Carcinoscorpius rotundicauda

Expression System: E. coli

Exotoxin A Protein, Pseudomonas aeruginosa, Recombinant (His & KSI)

Cat.No: TMPH-03168

Species: Pseudomonas aeruginosa

Expression System: E. coli

Porin P Protein, Pseudomonas aeruginosa, Recombinant (His & SUMO)

Cat.No: TMPH-03175

Species: Pseudomonas aeruginosa

Expression System: E. coli

PLC-H Protein, Pseudomonas aeruginosa, Recombinant (His & Myc & SUMO)

Cat.No: TMPH-03169

Species: Pseudomonas aeruginosa

Expression System: E. coli

L-arabinose isomerase Protein, Bacillus subtilis, Recombinant (His & Myc)

Cat.No: TMPH-00167

Species: Bacillus subtilis

Expression System: E. coli

LpxC Protein, Pseudomonas aeruginosa, Recombinant (His & SUMO)

Cat.No: TMPH-03180

Species: Pseudomonas aeruginosa

Expression System: E. coli

LecA Protein, Pseudomonas aeruginosa, Recombinant (His)

Cat.No: TMPH-03174

Species: Pseudomonas aeruginosa

Expression System: E. coli

Retinoschisin Protein, Human, Recombinant (His)

Cat.No: TMPH-02034

Species: Human

Expression System: E. coli

OprF Protein, Pseudomonas aeruginosa, Recombinant (His)

Cat.No: TMPH-03173

Species: Pseudomonas aeruginosa

Expression System: E. coli

Lysyl endopeptidase Protein, Pseudomonas aeruginosa, Recombinant (His & SUMO)

Cat.No: TMPH-03171

Species: Pseudomonas aeruginosa

Expression System: E. coli

NIFH Protein, Rhizobium leguminosarum, Recombinant (GST & His & Myc)

Cat.No: TMPH-03407

Species: Rhizobium leguminosarum

Expression System: E. coli

PvdA Protein, Pseudomonas aeruginosa, Recombinant (His & SUMO)

Cat.No: TMPH-03170

Species: Pseudomonas aeruginosa

Expression System: E. coli

Aln g I Protein, Alnus glutinosa, Recombinant (E. coli, His)

Cat.No: TMPH-00045

Species: Alnus glutinosa

Expression System: E. coli

OprI Protein, Pseudomonas aeruginosa, Recombinant (His)

Cat.No: TMPH-03172

Species: Pseudomonas aeruginosa

Expression System: E. coli

Elastase Protein, Pseudomonas aeruginosa, Recombinant (His & SUMO)

Cat.No: TMPH-03166

Species: Pseudomonas aeruginosa

Expression System: E. coli

Beta-lactamase Protein, Pseudomonas aeruginosa, Recombinant (His & SUMO)

Cat.No: TMPH-03165

Species: Pseudomonas aeruginosa

Expression System: E. coli

LpxC Protein, Pseudomonas aeruginosa, Recombinant (His & Myc & SUMO)

Cat.No: TMPH-03179

Species: Pseudomonas aeruginosa

Expression System: E. coli

TusA Protein, Pseudomonas aeruginosa, Recombinant (His & SUMO)

Cat.No: TMPH-03178

Species: Pseudomonas aeruginosa

Expression System: E. coli

toxR Protein, Pseudomonas aeruginosa, Recombinant (His)

Cat.No: TMPH-03167

Species: Pseudomonas aeruginosa

Expression System: E. coli

IRF1 Protein, Human, Recombinant (GST & His)

Cat.No: TMPH-01552

Species: Human

Expression System: Baculovirus Insect Cells

Cat. No.	Product Name	Target	Signaling Pathways
TMID-0163	myo-Inositol-d6
	myo-Inositol-d6 是 myo-Inositol 的氘代化合物。myo-Inositol 的 CAS 号为 87-89-8。Inositol是一种细胞内磷酸化合物，参与细胞信号传导，可能刺激肿瘤细胞分化。
TMIJ-0383	D-arabinose-13C5
	D-arabinose-13C5 是 D-arabinose 的 13C 的标记化合物。D-arabinose 的 CAS 号为 10323-20-3。D-arabinose 是内源性代谢产物的一种。
T35697	Lauric Acid-13C
	Lauric acid-13C is intended for use as an internal standard for the quantification of lauric acid by GC- or LC-MS. Lauric acid is a medium-chain saturated fatty acid. It has been found at high levels in coconut oil.1Lauric acid induces the activation of NF-κB and the expression of COX-2, inducible nitric oxide synthase (iNOS), and IL-1α in RAW 264.7 cells when used at a concentration of 25 μM.2
T36408	Rhein-13C4 Rhein-13C4
	Rhein-13C4 is intended for use as an internal standard for the quantification of rhein by GC- or LC-MS. Rhein is an anti-inflammatory anthraquinone found in rhubarb and is the bioactive derivative of its prodrug diacerein . At 10 μM, rhein inhibits IL-1β signaling, suppressing signaling through NF-κB, and reduces the expression of the matrix metalloproteases MMP-1 and MMP-13.1 It inhibits IKKβ (IC50 = 11.8 μM), decreasing iNOS and IL-6 expression in LPS-stimulated macrophages but paradoxically i...

同位素标记化合物

myo-Inositol-d6

Cat.No: TMID-0163

D-arabinose-13C5

Cat.No: TMIJ-0383

Lauric Acid-13C

Cat.No: T35697

Cat.No: T36408

Synonym: Rhein-13C4

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