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Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T80551 |
Calpain inhibitor V
Mu-Val-HPh-FMK |
Antibiotic | Microbiology/Virology |
Calpain inhibitor V (Mu-Val-HPh-FMK) 为具抗衣原体活性的细胞渗透性不可逆钙蛋白酶抑制剂。 | |||
T77793 |
Azodicarbonamide
NSC 674447,ADA,HPH-116 |
Others | Others |
Azodicarbonamide是一个能通过针对nucleocapsid CCHC domains来抑制HIV-1及多种逆转录病毒的核衣壳抑制剂。在标准细胞抗病毒测试中,该化合物能够抑制HIV-1RF引起的CEM-SS细胞病变,其EC50值为38 µM。 | |||
T74244 |
HOE 33187-O-CONH-PEG4-phenol-thiophenone-NHPh-COOEt
|
Others | Others |
HOE 33187-O-CONH-PEG4-phenol-thiophenone-NHPh-COOEt 对pre-miR-21 RNA 具有抑制活性。HOE 33187-O-CONH-PEG4-phenol-thiophenone-NHPh-COOEt 具有研究肿瘤疾病的潜力,例如癌症,尤其是表达 miR-21 的癌症。 |
Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T1022 |
Hygromycin B
潮霉素B,Hygrovetine |
ribosome; Antibacterial; Antibiotic; Antifungal | Microbiology/Virology |
Hygromycin B (Hygrovetine) 是一种氨基糖苷类抗生素,通过干扰易位并导致 70S 核糖体的错误翻译来抑制蛋白质合成。Hygromycin B 可用于筛选转染 hph 或 hyg 抗性基因的原核或者真核细胞。 |
Cat. No. | Product Name | Species | Expression System |
---|---|---|---|
TMPH-00639 |
Hygromycin-B 4-O-kinase Protein, E. coli, Recombinant (His)
Hygromycin B phosphotransferase,hph,Hygromycin-B ki... |
E. coli | E. coli |
The aminoglycoside phosphotransferases achieve inactivation of their antibiotic substrates by phosphorylation. Only phosphorylates hygromycin and closely related compounds such as demethyl analogs and destomycin. | |||
TMPH-01280 |
EGLN1 Protein, Human, Recombinant (His & Myc)
HPH-2,EGLN1,PHD2,SM-20,HIF-prolyl hydroxylase 2,HIF... |
Human | E. coli |
Cellular oxygen sensor that catalyzes, under normoxic conditions, the post-translational formation of 4-hydroxyproline in hypoxia-inducible factor (HIF) alpha proteins. Hydroxylates a specific proline found in each of the oxygen-dependent degradation (ODD) domains (N-terminal, NODD, and C-terminal, CODD) of HIF1A. Also hydroxylates HIF2A. Has a preference for the CODD site for both HIF1A and HIF1B. Hydroxylated HIFs are then targeted for proteasomal degradation via the von Hippel-Lindau ubiquiti... |