668
76
4
179
36
Cat. No. | Product Name | ||
---|---|---|---|
L2400 | 内分泌激素分子库 | 784 compounds | |
784 种与内分泌系统相关的生物活性小分子化合物的特有集合,用于高通量、高内涵筛选; | |||
L1380 | 转录因子库 | 695 compounds | |
695 种转录因子靶向、结构新颖的化合物; | |||
L3300 | 组胺&褪黑色素化合物库 | 153 compounds | |
153 种生物活性小分子化合物,用于高通量、高内涵筛选; | |||
L2191 | 抗乳腺癌化合物库 | 1939 compounds | |
1939 种与乳腺癌相关的化合物,可以用于抗乳腺癌药物研发和药理研究; |
Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T21535 |
Parathyroid Hormone (1-34), bovine
|
Thyroid hormone receptor(THR) | Endocrinology/Hormones |
Parathyroid Hormone (1-34), bovine 是一种甲状旁腺激素 (PTH) 受体激动剂,是甲状旁腺激素的一部分。 Parathyroid Hormone (1-34), bovine 可用于研究骨质疏松症和甲状旁腺功能衰退。 | |||
TP1104L |
Melanin Concentrating Hormone, salmon acetate
MCH (salmon),Melanin Concentrating Hormone, salmon acetate(87218-84-6 free base) |
Others; Melanin-concentrating Hormone Receptor (MCHR) | GPCR/G Protein; Others |
Melanin Concentrating Hormone, salmon acetate (MCH (salmon))(87218-84-6 free base) 是一种 19 个氨基酸的环状肽,主要在下丘脑中表达。 | |||
T7627L |
Adrenocorticotropic Hormone (ACTH) (4-10) TFA
Adrenocorticotropic Hormone (ACTH) (4-10) TFA(4037-01-8(free base)),Acth (4-10) |
Melanocortin Receptor | GPCR/G Protein; Neuroscience |
Adrenocorticotropic Hormone (ACTH) (4-10) TFA (Acth (4-10)) 是一种有效的黑皮质素 (MC4R) 受体激动剂。 | |||
TP1155L |
Human growth hormone-releasing factor acetate
|
GHSR | GPCR/G Protein |
Human growth hormone-releasing factor acetate 是一种下丘脑多肽,通过与垂体前叶细胞上的 GHRH 受体 (GHRHR) 结合来刺激 GH 的产生和释放。 | |||
T7407 |
Thyrotropin-Releasing Hormone (TRH), Free Acid
TRH-OH |
Others | Others |
Thyrotropin-Releasing Hormone (TRH), Free Acid (TRH-OH) 是一种促甲状腺激素释放激素的生理代谢产物。 | |||
T5015 |
Gonadorelin Acetate (33515-09-2 free base)
醋酸戈那瑞林,Luteinizing Hormone Releasing Hormone (LH-RH),Luteinizing Hormone Releasing Hormone (LH-RH), human,Gonadorelin Acetate |
Reductase | Endocrinology/Hormones; Metabolism |
Gonadorelin Acetate (33515-09-2 free base) (Luteinizing Hormone Releasing Hormone (LH-RH)) 是下丘脑神经肽,在控制生殖功能中起关键作用。 | |||
TP1112L |
LH-RH, salmon acetate(86073-88-3 free base)
Luteinizing Hormone Releasing Hormone (LH-RH), salmon acetate |
Others | Others |
LH-RH, salmon acetate(86073-88-3 free base) (Luteinizing Hormone Releasing Hormone (LH-RH), salmon acetate) 是一种在下丘脑中合成的垂体激素,在控制生殖功能中起着至关重要的作用。 | |||
TP1155 |
Human growth hormone-releasing factor
Growth Hormone Releasing Factor human |
||
Human growth hormone-releasing factor stimulates GH production and release by binding to the GHRH Receptor (GHRHR) on cells in the anterior pituitary.Growth hormone-releasing hormone is a hormone produced in the hypothalamus. The main role of growth hormo | |||
TP1248L |
ACTH 11-24 acetate(4237-93-8 free base)
Adrenocorticotropic Hormone (11-24) acetate |
Melanocortin Receptor | GPCR/G Protein; Neuroscience |
ACTH 11-24 acetate(4237-93-8 free base) (Adrenocorticotropic Hormone (11-24) acetate) 是促肾上腺皮质激素的片段,可诱导皮质醇释放。 ACTH (11-24) 已被确定为分离的肾上腺细胞中 ACTH (1-39) 和 ACTH (1-10) 的竞争性拮抗剂。 | |||
T9857 |
Vasopressin
antidiuretic hormone (ADH),argipressin,arginine vasopressin (AVP) |
Endogenous Metabolite | Metabolism |
Vasopressin (argipressin) 是一种由下丘脑神经元合成的环状九肽,是肽原激素合成中的一种激素。Vasopressin 参与下丘脑-垂体-肾上腺轴调节过程,增加无溶质水从肾小管的滤液中重新吸收回循环中的量,收缩小动脉提高压强,增强促肾上腺皮质激素释放因子的刺激作用调节垂体促肾上腺皮质激素分泌。Vasopressin 在神经传导过程中可作为神经递质,与特定的 G 蛋白偶联受体结合发挥作用。 | |||
TP1238L |
ACTH 1-14 acetate(25696-21-3 free base)
Adrenocorticotropic Hormone Fragment 1-14 acetate |
Adrenergic Receptor | GPCR/G Protein; Neuroscience |
ACTH 1-14 acetate(25696-21-3 free base) (Adrenocorticotropic Hormone Fragment 1-14 acetate) 是促肾上腺皮质激素的片段,可调节皮质醇和雄激素的产生。促肾上腺皮质激素 (ACTH),也称为促肾上腺皮质激素,由垂体前叶产生和分泌。作为对生物应激的反应,ACTH 是下丘脑-垂体-肾上腺轴的重要组成部分。 | |||
T7627 |
Adrenocorticotropic Hormone (ACTH) (4-10), human
Adrenocorticotropic Hormone (ACTH) (4-10),ACTH (4-10), human,Acth (4-10) |
Melanocortin Receptor | GPCR/G Protein; Neuroscience |
Adrenocorticotropic Hormone (ACTH) (4-10), human 是黑皮质素 4 型受体 (melanocortin 4 receptor, MC4R) 激动剂。 | |||
T8231 |
ACTH (1-39) human
Adrenocorticotropic Hormone (ACTH) (1-39), human,ACTH (1-39), human,丝拉克肽 |
Others | Others |
Adrenocorticotropic Hormone (ACTH) (1-39), human (ACTH (1-39), human) 是黑皮质素受体激动剂。 | |||
T36767 |
Parathyroid Hormone (1-13) (trifluoroacetate salt)
|
Others | Others |
Parathyroid hormone (PTH) (1-13) is an N-terminal fragment of PTH (1-34) . In vivo, PTH (1-13) (0.003-1 μmol/kg) increases mean arterial pressure (MAP) in anesthetized rats. | |||
TP1244L1 |
ACTH (1-10) Acetate (human)
Adrenocorticotropic Hormone (ACTH) (1-10), human acetate(2791-05-1 Free base) |
Others | Others |
Adrenocorticotropic Hormone (ACTH) (1-10), human acetate 是促肾上腺皮质激素的一个片段。 Adrenocorticotropic Hormone (ACTH) (1-10), human acetate 仅在 100 和 1000 nM 时具有较弱的 α-MSH 效力。 | |||
T40491 |
Luteinizing hormone (human)
|
||
Luteinizing hormone (LH), a heterodimeric glycoprotein hormone synthesized by the pituitary gland, serves vital functions in human reproductive processes. | |||
TP1112 |
Luteinizing Hormone Releasing Hormone (LH-RH), salmon
LH-RH, salmon |
||
Luteinizing Hormone Releasing Hormone (LH-RH) is a pituitary Hormone synthesized in the hypothalamus and plays a crucial role in the control of reproductive function. | |||
TP1104 |
Melanin Concentrating Hormone, salmon
MCH (salmon) |
||
Melanin Concentrating Hormone (MCH), a 19 amino acid cyclic peptide, is largely expressed in the hypothalamus. | |||
TP1964 |
Parathyroid hormone (1-34) (rat)
|
||
Parathyroid hormone (PTH) receptor agonist. Increases serum PTH levels and bone mass in rats. | |||
T7813 |
α-MSH
MSH, amide,CZEN-002,美拉诺坦,α-Melanocyte-Stimulating Hormone (MSH), amide |
Melanocortin Receptor; Adenylyl cyclase | GPCR/G Protein; Neuroscience |
α-MSH (MSH, amide) 是一种内源性神经肽,是一种内源性黑皮质素受体 4 (MC4R) 激动剂,具有抗炎和解热活性。 | |||
TP1513 |
Egg Laying Hormone, aplysia
|
||
Egg-laying hormone (ELH) is a neuropeptide synthesized by the bag cell neurons, Egg-laying hormone (ELH) induces egg laying and its correlated behavior in Aplysia californica. Egg-laying hormone (ELH) has been purified to homogeneity and Egg-laying hormon | |||
T73663 |
Adrenocorticotropic hormone
|
Others | Others |
Adrenocorticotropic hormone (ACTH) 是一种由垂体前叶分泌的促肾上腺皮质激素(tropic hormone),能够调节皮质醇和雄激素的产生。 | |||
TP1757 |
Adipokinetic Hormone (AKH) (24-32), locust
|
||
Adipokinetic Hormone (AKH) (24-32), locust is a peptide hormone isolated from locusts. | |||
TP1249 |
Adrenocorticotropic Hormone (ACTH) (1-39), rat
ACTH (1-39) (mouse, rat) |
||
Adrenocorticotropic Hormone (ACTH) (1-39), rat is a potent melanocortin 2 (MC2) receptor agonist.Peptide fragments of ACTH (1-39) were formed during in vitro incubation of the peptide with membrane preparations. ACTH (1-39) were isolated by high pressure | |||
TP1004 |
β-Melanocyte Stimulating Hormone (MSH), human
Beta-MSH (1-22) (human) |
||
Stimulating -Melanocyte Stimulating Hormone (MSH), human TFA, is a 22 peptide and is an endogenous melanocortin-4 receptor.MC4 - R) agonists. | |||
TP1244 |
Adrenocorticotropic Hormone (ACTH) (1-10), human
ACTH (1-10), human |
||
Adrenocorticotropic Hormone (ACTH) (1-10), human is a fragment of the adrenocorticotropin hormone. It exhibits a weak potency of α-melanocyte stimulating hormone (α-MSH), but only at high doses (100 and 1000 nM). | |||
T34869 |
Thyrotropin-releasing hormone, deamido-
Deamido-trh,Pyroglutamyl-histidyl-proline,Trh-OH,Trh, deamido-,Pglu-his-pro |
Others | Others |
Thyrotropin-releasing hormone, deamido- is a biochemical. | |||
T73692 |
Parathyroid hormone
|
Others | Others |
Parathyroid hormone (PTH) 是一种含84个氨基酸的循环激素,由甲状旁腺分泌。它主要针对骨骼和肾脏工作,功能是维持细胞外钙浓度在正常水平。此外,Parathyroid hormone 在骨质疏松症的研究中有重要应用。 | |||
T10251 |
Adrenocorticotropic Hormone (ACTH) (1-39), rat TFA
ACTH (1-39) (mouse, rat) TFA |
Others | Others |
Adrenocorticotropic Hormone (ACTH) (1-39), rat (TFA) is a potent melanocortin 2 receptor (MC2) agonist. | |||
TP1241 |
Adrenocorticotropic Hormone (ACTH) (18-39), human
ACTH (18-39), human |
||
Adrenocorticotropic Hormone (ACTH) (18-39) is known as the Corticotropin-like Intermediate Lobe Peptide. It stimulates insulin secretion as well as amylase and protein secretion in a dose-dependent manner similar to those of secretin and carbamylcholine. | |||
TP2283 |
parathyroid hormone (7-34) [Homo sapiens]/[Macaca fascicularis]
|
Others | Others |
parathyroid hormone (7-34) [Homo sapiens] [Macaca fascicularis] is a peptide with the sequence H2N-LMHNLGKHLNSMERVEWLRKKLQDVHNF-OH, MW= 3474.03. Parathyroid hormone (PTH) is secreted by the chief cells of the parathyroid glands as a polypeptide containing | |||
T78515 |
Follicle-stimulating hormone
|
Others | Others |
卵泡刺激素(Follicle-stimulating hormone, FSH)为一种由垂体前叶分泌的异二聚体糖蛋白,其参与调控动物的生殖能力与繁殖效率。 | |||
T6956L |
Protirelin Acetate(24305-27-9 free base)
Thyroliberin Acetate,TRF Acetate,Synthetic thyrotropin-releasing hormone Acetate,Lopremone Acetate,pGlu-His-Pro-NH2 Acetate,TRH Acetate |
Thyroid hormone receptor(THR) | Endocrinology/Hormones |
Protirelin Acetate(24305-27-9 free base) (Thyroliberin Acetate) 是一种三肽,可刺激促甲状腺素和催乳素的释放。 | |||
T83165 |
Adipokinetic hormone (Manduca sexta)
Manse-AKH |
||
Adipokinetic Hormone (Apis mellifera ligustica, Bombyx mori, Heliothis zea, Manduca sexta) 是昆虫肽类激素,能强烈诱导促脂肪/高海藻素反应,但不具备糖原动员功能,亦不能在脂肪体内有效储存及利用糖原。 | |||
T73664 |
Adrenocorticotropic hormone TFA
|
||
Adrenocorticotropic hormone (ACTH) TFA,是由垂体前叶分泌,用于调节皮质醇和雄激素产生的促肾上腺皮质激素。 | |||
T76304 |
Adipokinetic hormone II (Locusta migratoria)
|
||
Adipokinetic hormone II (Locusta migratoria) (Lom-AKH-II),一昆虫AKH,可提升脂肪体cAMP水平。AKHs通过其受体和Gs蛋白相互作用,增强cAMP生成与糖原磷酸化酶活性,从而直接调控飞蝗脂肪体中碳水化合物与脂质的动员。 | |||
T76306 |
Adipokinetic hormone I (Locusta migratoria)
|
||
Adipokinetic hormone I (Locusta migratoria) (Lom-AKH-I) 是昆虫脂肪运动激素(AKH)类,可促进脂肪体内cAMP水平升高。AKH通过与AKH受体结合,并通过刺激性鸟嘌呤核苷酸结合蛋白(Gs)偶联,促进cAMP生成及糖原磷酸化酶活化,从而控制飞蝗动员脂肪体存储的碳水化合物和脂质。 | |||
TP1249L |
Adrenocorticotropic Hormone (ACTH) (1-39), rat acetate(77465-10-2 Free base)
|
||
Adrenocorticotropic Hormone (ACTH) (1-39), rat acetate(77465-10-2 Free base) 是一种有效的黑皮质素 2 (MC2) 受体激动剂。ACTH (1-39) 的肽片段是在体外孵育过程中形成的 肽与膜制剂。 | |||
TP1240 |
ACTH (18-39) TFA (human)
CLIP (human) (TFA) |
Others | Others |
Adrenocorticotropic Hormone (ACTH) (18-39), human TFA (CLIP human TFA) 是一种似皮质促素中叶肽,由垂体中叶的促黑素细胞产生。 | |||
T83166 |
Adipokinetic hormone (Gryllus bimaculatus)
Grybi-AKH |
||
Adipokinetic hormone Gryllus bimaculatus (Grybi-AKH) 是调节昆虫能量平衡的脂肪动力激素,主要功能是动员脂肪体内的脂质和碳水化合物。此外,Grybi-AKH也能增强双斑蟋蟀的运动活性,并在人体体重调节、体重减轻及糖原贮积障碍缓解的研究中具有应用潜力。 | |||
T82322 |
GHRF, mouse
Mouse growth hormone-releasing factor |
||
GHRF, mouse为含44个氨基酸的小鼠生长激素释放肽,能够促进生长激素的释放与合成。 | |||
T34684 |
Somatotropin (6-13)
Human growth hormone (6-13) |
Others | Others |
Somatotropin (6-13) is a growth hormone. | |||
T83178 |
ACTH (6-24) (human)
Adrenocorticotropic hormone (6-24) |
||
ACTH (6-24) (human)(腎上腺皮質激素(6-24))是腎上腺皮質激素的片段。該化合物作為ACTH (1-39) 和 ACTH (5-24) 引起的類固醇生成的競爭性抑制劑,具有相應的Kd值分別為13.4和3.4nM。此外,ACTH (6-24) (human) 能夠抑制 hPTH 1-34 所誘導的皮質酮產生以及cAMP的累積。 | |||
T75970 |
Melanin Concentrating Hormone, salmon TFA
|
||
Melanin Concentrating Hormone, salmon TFA (MCH (salmon) TFA) 是在硬骨鱼的垂体中发现的 19 个氨基酸组成的神经肽,它调节食物摄入,能量平衡,睡眠状态和心血管系统。Melanin Concentrating Hormone, salmon TFA (MCH (salmon) TFA) 是 SLC-1/GPR24和 MCHR2的配体。 | |||
T76084 |
Parathyroid Hormone (1-34), human, biotinylated
|
||
Parathyroid Hormone (1-34), human, biotinylated 作为甲状旁腺激素受体的高效探针,其主要应用于活细胞中探索甲状旁腺激素与其受体之间的动态相互作用,并可利用亲和柱技术对激素-受体复合物进行精确纯化。 | |||
T76061 |
Parathyroid hormone (1-34) (rat) acetate
|
||
Parathyroid hormone (1-34) (rat) (acetate) 是一种甲状旁腺激素,主要用于骨质疏松症的研究,具有改善皮质和松质骨结构的功能。 | |||
T75971 |
γ-1-Melanocyte Stimulating Hormone (MSH), amide
|
||
γ-1-Melanocyte Stimulating Hormone (MSH), amide为含11个氨基酸的多肽,主要通过激活黑皮质素受体3 (MC3-R) 调节钠 (Na+) 平衡及血压。 | |||
TP1245 |
ACTH (4-11)
ACTH 4-11,Adrenocorticotropic Hormone (4-11), human |
||
ACTH (4-11) is a peptide fragment of adrenocorticotropic hormone, a peptide hormone found in the brain that is involved in the biological stress response. | |||
TP1247 |
ACTH (1-13)
Adrenocorticotropic Hormone (1-13),ACTH 1-13 |
||
ACTH (1-13) is a 13-aa peptide, with cytoprotective effects in the model of ethanol induced gastric lesions in rats.Adrenocorticotropic hormone (ACTH), also known as corticotropin, is produced and secreted by the anterior pituitary gland. ACTH is an impor | |||
TP1248 |
ACTH (11-24)
ACTH 11-24,Adrenocorticotropic Hormone (11-24) |
||
ACTH (11-24) is a fragment of adrenocorticotrophin, induces cortisol release. ACTH (11-24) has been identified as a competitive antagonist of ACTH (1-39) and ACTH (1-10) in isolated adrenal cells. |
Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T5026 |
Oxytocin
催产素,α-Hypophamine,Oxytocic hormone,Oxytocin (Syntocinon) |
Oxytocin Receptor | Endocrinology/Hormones; GPCR/G Protein |
Oxytocin (Oxytocin (Syntocinon)) 是哺乳动物的神经垂体激素,是多效的下丘脑肽,是催产素受体的配体,有助于分娩、哺乳和亲社会行为。它可作为一种压力应对分子,具有抗炎、抗氧化剂和保护作用。 | |||
T6956 |
Protirelin
Lopremone,pGlu-His-Pro-NH2,Synthetic thyrotropin-releasing hormone,Thyroliberin,TRH,普罗瑞林,TRF |
Thyroid hormone receptor(THR); Endogenous Metabolite | Endocrinology/Hormones; Metabolism |
Protirelin (Thyroliberin) 是高度保守的神经肽,具有促甲状腺激素水平的激素控制作用,及神经调节功能。 | |||
T5145 |
Oxytocin acetate
Oxytocic hormone acetate,α-Hypophamine acetate,Oxytocin acetate (50-56-6 free base),醋酸催产素 |
Oxytocin Receptor | Endocrinology/Hormones; GPCR/G Protein |
Oxytocin acetate (α-Hypophamine acetate) 是哺乳动物的神经垂体激素,是多效的下丘脑肽,是催产素受体的配体,有助于分娩、哺乳和亲社会行为。它可作为一种压力应对分子,具有抗炎、抗氧化剂和保护作用。 | |||
T83531 |
(Rac)-Juvenile hormone III
|
||
(Rac)-Juvenile hormone III,一种自法脂酸分离的天然产物,作为幼体激素的同源物具有最广泛分布。 | |||
T7999 |
7-Hydroxyflavanone
|
Anti-infection | Microbiology/Virology |
7-Hydroxyflavanone 对肺炎链球菌临床分离株显示出抗菌活性。 | |||
T41372 |
(22S,23S)-Homobrassinolide
油菜素内酯,SSHB |
Others | Others |
(22S,23S)-Homobrassinolide (SSHB) 在各种植物生物测定试验中均能诱导植物生长。 | |||
T1009 |
Estrone
Oestrone,雌酮,Fluoroethyl,Aquacrine |
Estrogen Receptor/ERR; Estrogen/progestogen Receptor; Endogenous Metabolite | Endocrinology/Hormones; Metabolism |
Estrone (Aquacrine) 是内源性雌激素的主要代表,由多种组织产生,尤其是脂肪组织。它是脂肪细胞中雄烯二酮芳构化过程的结果。 | |||
T3014 |
(±)-Abscisic acid
Abscisic acid,Dormin,脱落酸,Abscisinsaeure |
Others | Others |
(±)-Abscisic acid 是一种口服具有活性的植物激素,也存在与动物中。它可以调节哺乳动物的血糖。 | |||
T15133 |
Dinoprost
Prostaglandin F2a,PGF2α,地诺前列素 |
Endogenous Metabolite | Metabolism |
Dinoprost (Prostaglandin F2a) 是口服有效的、内源性的前列腺素 F 受体激动剂。它是在子宫内膜腔上皮和黄体中局部产生的溶酶激素。它在分娩过程中起关键作用。 | |||
T2223 |
Kinetin
激动素,6-Furfuryladenine,6-糠氨基嘌呤,N6-Furfuryladenine |
Others | Others |
Kinetin (N6-Furfuryladenine) 是 N6-取代腺嘌呤衍生物细胞分裂素家族成员,其中细胞分裂素是一种参与细胞分裂、分化等生理过程的植物生长激素。它具有抗衰老活性。 | |||
T5568 |
H-Tyr(3-I)-OH
3-碘-L-酪氨酸,3-Iodo-L-tyrosine |
Endogenous Metabolite | Metabolism |
H-Tyr(3-I)-OH (3-Iodo-L-tyrosine) 是酪氨酸羟化酶抑制剂和甲状腺激素 的中间体。 | |||
T1653 |
Liothyronine
Tresitope,O-(4-Hydroxy-3-iodophenyl)-3,5-diiodo-L-tyrosine,碘噻罗宁,Triiodothyronine,三碘甲状腺原氨酸,L-3,3',5-Triiodothyronine,3,3',5-Triiodo-L-thyronine,Lyothyronine |
Thyroid hormone receptor(THR); Endogenous Metabolite | Endocrinology/Hormones; Metabolism |
Liothyronine (Tresitope) 是一种人工合成的甲状腺激素,能够激活 β1 甲状腺激素受体 (TRβ1)。Liothyronine 能促进糖、蛋白质和脂肪三大物质的代谢,加速组织细胞的氧化过程,维持正常的基础代谢率,有利于机体的生长发育。 | |||
T0864 |
L-Thyroxine
Levothyroxine,NSC 36397,L-甲状腺素,T4 |
Thyroid hormone receptor(THR); Endogenous Metabolite | Endocrinology/Hormones; Metabolism |
L-Thyroxine (NSC 36397) 是一种合成的甲状腺激素,用于甲状腺功能减退症的研究。在 DIO 酶作用下,L-Thyroxine (NSC 36397) 转化成具有生物特性的三碘甲状腺氨酸(T3)。 | |||
T2207 |
Adrenosterone
肾上腺甾酮,11-ketoandrostenedione,11-oxoandrostenedione,Reichstein's substance G |
Androgen Receptor; Endogenous Metabolite | Endocrinology/Hormones; Metabolism |
Adrenosterone (11-ketoandrostenedione) 是一种人内源性代谢物,由肾上腺皮质产生。Adrenosterone 是一种竞争性羟基类固醇脱氢酶 1 抑制剂。它是一种的类固醇激素,具有较弱的雄激素特性。它是一种膳食补充剂,能够减少脂肪并提高肌肉质量。它能够抑制人类癌细胞的转移进展。 | |||
T20945 |
2,4-D
Hedonal,Macondray,2,4-D acid,Chloroxone,2,4-二氯苯氧乙酸 |
DNA/RNA Synthesis | Cell Cycle/Checkpoint; DNA Damage/DNA Repair |
2,4-Dichlorophenoxyacetic acid (Hedonal) 是一种合成生长素,用作植物生长调节剂,也用作植物细胞培养基中的补充剂。它是除草剂中的一种活性成分,用于破坏肌动蛋白细胞骨架,以控制根系伸长和细胞生成。 | |||
T2881 |
Crustecdysone
Commisterone,B-ecdysone,Commisterone,20-Hydroxyecdysone,Ecdysterone,B-ecdysone,β-蜕皮甾酮,Hydroxyecdysone,羟基蜕皮激素 |
Others; Caspase; Endogenous Metabolite; Autophagy | Apoptosis; Autophagy; Metabolism; Others; Proteases/Proteasome |
Crustecdysone (Hydroxyecdysone) 是来源于露水草的一种蜕皮激素,可调节昆虫的蜕皮或蜕皮过程。它是 Ecdysone 的活性代谢物,通过 20E 核受体复合物 EcR-USP 抑制半胱天冬酶活性并诱导自噬,在心血管系统中具有调节或保护作用。 | |||
T16442 |
PCO371
2,4-Imidazolidinedione, 1-(3,5-dimethyl-4-(2-((4-oxo-2-(4-(trifluoromethoxy)phenyl)-1,3,8-triazaspiro(4.5)dec-1-en-8-yl)sulfonyl)ethyl)phenyl)-5,5-dimethyl- |
Thyroid hormone receptor(THR) | Endocrinology/Hormones |
PCO371 (2,4-Imidazolidinedione, 1-(3,5-dimethyl-4-(2-((4-oxo-2-(4-(trifluoromethoxy)phenyl)-1,3,8-triazaspiro(4.5)dec-1-en-8-yl)sulfonyl)ethyl)phenyl)-5,5-dimethyl-) 是口服具有活性的甲状旁腺激素受体 1 的完全激动剂,对 PTHR2 无作用 | |||
T1048 |
Estradiol
雌二醇,E2,17β-Estradiol,17β-Oestradiol,β-Estradiol |
Estrogen Receptor/ERR; Estrogen/progestogen Receptor; Endogenous Metabolite | Endocrinology/Hormones; Metabolism |
Estradiol (E2) 是一种天然的类固醇性激素,对于女性生育能力和第二性征的维持至关重要。Estradiol 通过雌激素受体 β (ERβ) 上调 IL-6 表达。 | |||
TN3910 |
Ecdysone
|
Apoptosis; ATPase; Glucocorticoid Receptor; Potassium Channel; Sodium Channel; Endogenous Metabolite; Autophagy | Apoptosis; Autophagy; Endocrinology/Hormones; Membrane transporter/Ion channel; Metabolism |
Ecdysone 是存在于昆虫和草药中的主要类固醇激素,可以激活盐皮质激素受体并诱导细胞凋亡。Ecdysone 的活性代谢物 20-羟基蜕皮激素在协调发育过渡和体内稳态睡眠调节中起重要作用。 | |||
T7931 |
16a,17a-Epoxy-4-Pregnen-3,20-Dione
|
Others | Others |
16a,17a-Epoxy-4-Pregnen-3,20-Dione 是一种合成孕激素,是黄体酮激素的代谢产物,它通过与黄体酮受体结合发挥作用,已被用于研究孕激素对生殖器官的影响,激素对细胞生长和发育的影响,以及激素对免疫系统的影响。 | |||
T0551 |
D-Ornithine hydrochloride
D-Ornithine HCl,D-鸟氨酸盐酸盐,D-Ornithine monohydrochloride |
Others; Endogenous Metabolite | Metabolism; Others |
D-Ornithine monohydrochloride 是内源性代谢产物的一种,可调节肌肉内激素水平,可用来研究皮肤干燥和失眠。 | |||
T21130 |
Precocene II
早熟素Ⅱ,AI3-36847,Ageratochromene,BRN 0160683 |
Others | Others |
Precocene II (Ageratochromene) 是一种抗异体激素化合物,可抑制保幼激素的生物合成。 Precocene II 具有杀虫、抗真菌、抗菌和抗氧化活性。 | |||
T4869 |
D-Allose
阿洛糖,β-D-Allopyranose,D-(+)-ALLOSE |
Others; Endogenous Metabolite | Metabolism; Others |
D-Allose (β-D-Allopyranose) 是内源性代谢产物的一种。 | |||
T0301 |
Ethisterone
炔孕酮,17α-Ethynyltestosterone,Pregneninolone |
Estrogen Receptor/ERR; Estrogen/progestogen Receptor | Endocrinology/Hormones |
Ethisterone (17α-Ethynyltestosterone) 是一种口服活性类固醇避孕药,是一种合成类固醇雌激素。据报道,它具有雄激素活性,用于妇科疾病的研究。 | |||
T3665 |
Tectoridin
射干苷,Shekanin |
Estrogen Receptor/ERR; Reductase | Endocrinology/Hormones; Metabolism |
Tectoridin (Shekanin) 是分离自 Maackia amurensis 中的异黄酮,是一种植物雌激素,能够激活雌激素和甲状腺激素受体。它通过 ER 依赖性基因组途径和 GPR30 依赖性非基因组途径发挥雌激素作用。 | |||
T7974 |
Lynestrenol
|
Progesterone Receptor | Others |
Lynestrenol 是孕烷 X 受体 (PXR) 激动剂,能够作用于 hPXR(EC50:41 µM) 和 zfPXR(EC50:0.23 µM)。它是合成的孕酮,具有免疫刺激作用。 | |||
T2748 |
Cortodoxone
可托多松,11-Deoxycortisol,cortexolone,17α,21-dihydroxyprogesterone,Reichstein's substance S,11-Desoxycortisol |
Glucocorticoid Receptor; Endogenous Metabolite | Endocrinology/Hormones; Metabolism |
Cortodoxone (11-Desoxycortisol) 是糖皮质类固醇激素,能够氧化为皮质醇。 | |||
T3151 |
Brassinolide
Brassin lactone,24-Epibrassinolide,芸苔素内酯 |
Apoptosis; Others | Apoptosis; Others |
Brassinolide (Brassin lactone) 是一种植物生长调节剂,可调节植物细胞伸长。 | |||
T4461 |
3,5-Diiodo-L-thyronine
3,5-二碘-L-甲状腺素,Diiodothyronine |
Thyroid hormone receptor(THR); Endogenous Metabolite | Endocrinology/Hormones; Metabolism |
3,5-Diiodo-L-thyronine (Diiodothyronine) 是内源性代谢产物的一种。 | |||
TC0025 |
Testosterone acetate
NSC523836,NSC-523836,NSC 523836,醋酸睾酮 |
Others | Others |
Testosterone acetate (NSC-523836) 是一种 Testosterone 前药,是一种天然存在的雄激素睾酮酯。它可用于阳痿、虚弱、疲劳和性腺机能减退的研究。 | |||
T30784 |
Cedrene
AI3 51328,AI351328,AI3-51328 |
||
Cedrene (AI3-51328) 从贵州木霉 NJAU4742 中提取到的倍半萜化合物,可促进植物侧根形成,通过生长素的转运和信号传导发挥作用。 | |||
T2955 |
Gibberellic acid
GA3,Gibberellin A3,赤霉酸,赤霉素,Gibberellin |
Others | Others |
Gibberellic acid (GA3) 是由真菌 Gibberella fujikuroi 命名而来。它能够调节植物发育和生长的过程(包括种子发育和发芽,茎和根的生长,细胞分裂和开花时间)。 | |||
T10048 |
17a-Hydroxypregnenolone
|
Endogenous Metabolite | Metabolism |
17a-Hydroxypregnenolone 是一种孕烷类固醇, 是形成脱氢表雄酮的激素原。17a-Hydroxypregnenolone 是一种神经调节剂。 | |||
T20003 |
Acridone
|
Antibacterial; ABC | Membrane transporter/Ion channel; Microbiology/Virology |
Acridone 具有抗菌、抗疟、抗病毒和抗肿瘤活性。它可诱导细胞凋亡,抑制 ABCG2 蛋白,并调节激素水平。 | |||
T2O2791 |
3-Indoleacetic acid
3-IAA,Indole-3-acetic acid,1H-Indole-3-acetic acid,3-吲哚乙酸,indolylacetic acid,IAA,indoleacetic acid |
Others; Endogenous Metabolite | Metabolism; Others |
3-Indoleacetic acid (indolylacetic acid) 是常见的天然植物生长激素。它可以诱导植物细胞的伸长和分裂。 | |||
T5040 |
Medroxyprogesterone
甲羟孕酮,甲孕酮 |
Estrogen/progestogen Receptor; Progesterone Receptor | Endocrinology/Hormones; Others |
Medroxyprogesterone 是一种合成的人孕酮变体,是孕酮受体激动剂,用于治疗肾癌。在兽医实践中用作发情调节剂。 | |||
T6361 |
Indole-3-butyric acid
3-Indolebutyric acid,3-吲哚丁酸,IBA,Hormodin |
Others; Endogenous Metabolite | Metabolism; Others |
Indole-3-butyric acid (IBA) 是一种植物生长素。 它能够促进草本植物和木本观赏植物生根,并用于提高果实率。 | |||
T3S0507 |
Homovanillic acid
Homovaniuic acid,Vanilacetic acid,高香草酸,Vanillacetic acid |
Others; Endogenous Metabolite | Metabolism; Others |
Homovanillic acid (Vanillacetic acid) 是一种多巴胺代谢物,它与乳糜泻、生长激素缺乏、芳香族氨基酸脱羧酶缺乏症以及脂联素还原酶缺乏症相关。 | |||
TMO2790 |
1-Naphthaleneacetic acid
Transplantone,1-Naphthylacetic acid,α-Naphthaleneacetic acid,Phyomone,1-萘乙酸 |
Phospholipase | Metabolism |
1-Naphthaleneacetic acid (Transplantone) 是一种 PLA2抑制剂,IC50=13.16 μM。它也是一种合成的植物生长素,可以促进植物生长。 | |||
TMS2181 |
trans-Zeatin
(E)-Zeatin,玉米素 |
ERK; MEK; Endogenous Metabolite | MAPK; Metabolism |
trans-Zeatin ((E)-Zeatin) 是植物细胞分裂素,可抑制紫外线诱导的MEK/ERK 的活化,在细胞生长、分化和分裂中起着重要的作用。 | |||
T7990 |
9-hydroxy-4-androstene-3,17-dione
|
Others | Others |
9-hydroxy-4-androstene-3,17-dione 是一种类固醇激素,具有抗肿瘤活性,可以抑制多种癌症细胞的生长,包括乳腺癌、前列腺癌和肺癌细胞。 | |||
T5014 |
Prostaglandin E2
地诺前列酮,前列腺素 E2,PGE2,Dinoprostone,Prostaglandin E2 (PGE2) |
Endogenous Metabolite; Prostaglandin Receptor | GPCR/G Protein; Immunology/Inflammation; Metabolism |
Prostaglandin E2 (PGE2) 是一种天然激素,参与人体内的各种生理过程,包括平滑肌收缩和放松、调节血管扩张和收缩、调节血压和炎症调节。 | |||
T0851 |
Pregnenolone
3β-Hydroxy-5-pregnen-20-one,Arthenolone,孕烯醇酮 |
Cannabinoid Receptor; Endogenous Metabolite; TRP/TRPV Channel; AChR; Autophagy | Autophagy; GPCR/G Protein; Membrane transporter/Ion channel; Metabolism; Neuroscience |
Pregnenolone (Arthenolone) 是一种由胆固醇合成的内源性类固醇激素,用于治疗阿尔茨海默病。它是大麻素 CB1受体的信号传导特异性抑制剂,抑制由 CB1受体介导的四氢大麻酚 的作用。它也是 TRPM3通道激活剂,也可弱激活 TRPM1通道。 | |||
T4834 |
Indole-3-acetamide
3-Indoleacetamide,3-Indolylacetamide,3-吲哚乙酰胺 |
Others; Endogenous Metabolite | Metabolism; Others |
Indole-3-acetamide 是一种 indole-3-acetic acid 的生物合成中间体。其中 Indole-3-acetic acid 是植物生长素类中最常见的天然植物生长激素。 | |||
T6316 |
Calcitriol
Topitriol,Rocaltrol,Calcijex,RO215535,骨化三醇,1,25-Dihydroxyvitamin D3 |
Endogenous Metabolite | Metabolism |
Calcitriol (1,25-Dihydroxyvitamin D3) 是一种维他命 D 的代谢物,一种维他命 D 受体 (VDR) 的激动剂 (IC50=0.4 nM)。Calcitriol 增加肠道对钙和磷的吸收,并与甲状旁腺激素一起增加了骨吸收。 | |||
T4939 |
Indole-3-pyruvic acid
3-(3-吲哚基)-2-氧代丙酸,3-(3-Indolyl)-2-oxopropanoic acid |
Others | Others |
Indole-3-pyruvic acid (3-(3-Indolyl)-2-oxopropanoic acid) 是一种参与Indole-3-acetic acid 生物合成的化合物,Indole-3-acetic acid 是一种植物激素,在调节生长和对环境变化的反应中起重要作用。 | |||
T1429 |
17α-Hydroxyprogesterone
Hydroxyprogesterone,17-OHP,羟孕酮,17-Hydroxyprogesterone,17α-羟孕酮 |
Estrogen/progestogen Receptor; Progesterone Receptor; Endogenous Metabolite | Endocrinology/Hormones; Metabolism; Others |
17α-Hydroxyprogesterone (17-OHP) 是一种内源性孕激素,其他类固醇激素(包括糖皮质激素,雌激素,和雄激素)生物合成的化学中间体。 | |||
T1614 |
Hydrocortisone
氢化可的松,Cortisol |
Glucocorticoid Receptor; Endogenous Metabolite | Endocrinology/Hormones; Metabolism |
Hydrocortisone (Cortisol) 是一种糖皮质激素,由肾上腺素皮质分泌。Hydrocortisone 激动糖皮质激素受体,可促进蛋白质分解代谢、糖异生、毛细血管壁稳定性、肾脏钙排泄,并抑制免疫和炎症反应。 | |||
T2598 |
Thymopentin
TP5,胸腺五肽 |
Estrogen/progestogen Receptor; Endogenous Metabolite | Endocrinology/Hormones; Metabolism |
Thymopentin (TP5) 是主要由胸腺皮质和髓质上皮细胞分泌的生物特性肽。它能促使自人类胚胎干细胞产生 T 细胞群。它是有效免疫调节剂,具有很短的血浆半衰期(30 秒)。 | |||
T6368 |
Abscisic Acid
Abscisin II,Dormin,(+)-脱落酸,(+)-ABA,Abscisic Acid (Dormin) |
Others; Proton pump; Endogenous Metabolite | Membrane transporter/Ion channel; Metabolism; Others |
Abscisic Acid (Dormin) 是具有口服活性的植物激素,存在于蔬菜和水果中,也是内源性的哺乳动物激素。它是生长抑制剂,可以调节植物生长发育。他抑制质子泵,并导致 Ca2+依赖性的质膜去极化。它是 LANCL2 的天然配体,属于胰岛素敏感化合物,在糖尿病前期,2 型糖尿病和代谢综合征的研究中具有价值。 | |||
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Cat. No. | Product Name | Species | Expression System |
---|---|---|---|
TMPY-05176 |
AMH Protein, Human, Recombinant (His)
MIS,anti-Mullerian hormone,MIF |
Human | HEK293 Cells |
Anti-Mullerian hormone (AMH), a member of the TGF-beta superfamily, is produced by granulosa cells (GCs) of preantral and small antral follicles and plays a role in regulating the recruitment of primordial follicles and the FSH-dependent development of follicles. BMP15 up-regulates the transcription of AMH and that the inhibition of p38 MAPK decreases the BMP15-induced expression of AMH and SOX9, suggesting that BMP15 up-regulates the expression of AMH via the p38 MAPK signaling pathway, and thi... | |||
TMPY-04281 |
GHR/Growth Hormone R Protein, Rat, Recombinant (hFc)
growth hormone receptor |
Rat | HEK293 Cells |
GHR/Growth Hormone R Protein, Rat, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 55.4 kDa and the accession number is P16310-1. | |||
TMPY-02007 |
GHR/Growth Hormone R Protein, Rat, Recombinant (His)
growth hormone receptor |
Rat | HEK293 Cells |
GHR/Growth Hormone R Protein, Rat, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 29.6 kDa and the accession number is P16310-1. | |||
TMPJ-00795 |
Growth Hormone Protein, Mouse, Recombinant
Gh1,Somatotropin,Gh,Growth Hormone |
Mouse | E. coli |
Somatotropin(GH) is a member of the somatotropin/prolactin family of hormones which play an important role in growth control. Its major role in stimulating body growth is to stimulate the liver and other tissues to secrete IGF-1. GH stimulates both the differentiation and proliferation of myoblasts. It also stimulates amino acid uptake and protein synthesis in muscle and other tissues. | |||
TMPY-01448 |
GHR/Growth Hormone R Protein, Mouse, Recombinant (His)
GHR/BP,growth hormone receptor,GHBP |
Mouse | HEK293 Cells |
GHR/Growth Hormone R Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 30.3 kDa and the accession number is Q3UP14. | |||
TMPY-00394 |
Growth Hormone Protein, Human, Recombinant
GHB5,GH-N,GH1,IGHD1B,hGH-N,GHN,Growth hormone 1,GH |
Human | E. coli |
Growth Hormone Protein, Human, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 22.1 kDa and the accession number is P01241. | |||
TMPJ-00356 |
GHR/Growth Hormone R Protein, Mouse, Recombinant (hFc)
GHBP,GHR,Somatotropin receptor,growth hormone recep... |
Mouse | HEK293 Cells |
Growth hormone receptor is a transmembrane receptor for growth hormone (GH). GH is a single-chain polypeptide that is mainly synthesized and released from the anterior pituitary gland and plays essential roles in growth, development and metabolism. GH exerts its physiological actions via GH binding to its receptor in its extracellular domain. Binding of growth hormone to the receptor leads to receptor dimerization and the activation of an intra- and intercellular signal transduction pathway lead... | |||
TMPY-00977 |
GHR/Growth Hormone R Protein, Mouse, Recombinant (His & hFc)
growth hormone receptor,GHR/BP,GHBP |
Mouse | HEK293 Cells |
GHR/Growth Hormone R Protein, Mouse, Recombinant (His & hFc) is expressed in HEK293 mammalian cells with His and hFc tag. The predicted molecular weight is 56.8 kDa and the accession number is Q3UP14. | |||
TMPY-00195 |
Growth Hormone Protein, Human, Recombinant (His)
GH-N,GHN,hGH-N,GH1,IGHD1B,GHB5,GH,growth hormone 1 |
Human | E. coli |
Growth Hormone Protein, Human, Recombinant (His) is expressed in E. coli expression system with His tag. The predicted molecular weight is 24.7 kDa and the accession number is P01241. | |||
TMPY-00186 |
GHRH Protein, Human, Recombinant (hFc)
GRF,INN,growth hormone releasing hormone,G... |
Human | HEK293 Cells |
The role of hypothalamic growth hormone-releasing hormone (GHRH) in the release of growth hormone (GH) from the pituitary is well established. Extra-hypothalamic growth hormone-releasing hormone (GHRH) plays an important role in infertility. Growth hormone releasing hormone (GHRH) has recently been shown to increase the level of gamma-aminobutyric acid (GABA) and activate GABA receptors (GABARs) in the cerebral cortex. GABA is an inhibitory neurotransmitter that can inhibit seizures. GHRH may pl... | |||
TMPH-02447 |
GH Protein, Rhesus macaque, Recombinant (His & Myc)
Growth hormone,Growth hormone 1,Somatotrop... |
Rhesus | E. coli |
Plays an important role in growth control. Its major role in stimulating body growth is to stimulate the liver and other tissues to secrete IGF-1. It stimulates both the differentiation and proliferation of myoblasts. It also stimulates amino acid uptake and protein synthesis in muscle and other tissues. GH Protein, Rhesus macaque, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 29.7 kDa and the accession number is ... | |||
TMPH-01618 |
LHCGR Protein, Human, Recombinant (His)
LHCGR,Luteinizing hormone receptor,Lutropin-choriog... |
Human | E. coli |
Receptor for lutropin-choriogonadotropic hormone. The activity of this receptor is mediated by G proteins which activate adenylate cyclase. LHCGR Protein, Human, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 41.6 kDa and the accession number is P22888. | |||
TMPZ-00002 |
GH2 Protein, Human, Recombinant (His)
Growth hormone 2,Placenta-specific growth hormo... |
Human | HEK294 Cells |
GH2 Plays an important role in growth control. Its major role in stimulating body growth is to stimulate the liver and other tissues to secrete IGF-1. It stimulates both the differentiation and proliferation of myoblasts. It also stimulates amino acid uptake and protein synthesis in muscle and other tissues. GH2 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 21.01 kDa and the accession number is P01242. | |||
TMPH-02522 |
GHRL Protein, Mouse, Recombinant (His)
Motilin-related peptide,Growth hormone-releasing pe... |
Mouse | E. coli |
Ghrelin is the ligand for growth hormone secretagogue receptor type 1 (GHSR). Induces the release of growth hormone from the pituitary. Has an appetite-stimulating effect, induces adiposity and stimulates gastric acid secretion. Involved in growth regulation.; Obestatin may be the ligand for GPR39. May have an appetite-reducing effect resulting in decreased food intake. May reduce gastric emptying activity and jejunal motility. GHRL Protein, Mouse, Recombinant (His) is expressed in E. coli expre... | |||
TMPY-02764 |
PTH Protein, Human, Recombinant (aa 32-65, GST)
parathyroid hormone,PTH1,PTH |
Human | E. coli |
PTH Protein, Human, Recombinant (aa 32-65, GST) is expressed in E. coli expression system with GST tag. The predicted molecular weight is 31 kDa and the accession number is P01270. | |||
TMPH-03322 |
LHCGR Protein, Rat, Recombinant (His & SUMO)
Luteinizing hormone receptor,Lutropin-choriogonadot... |
Rat | E. coli |
Receptor for lutropin-choriogonadotropic hormone. The activity of this receptor is mediated by G proteins which activate adenylate cyclase. LHCGR Protein, Rat, Recombinant (His & SUMO) is expressed in E. coli expression system with N-6xHis-SUMO tag. The predicted molecular weight is 53.2 kDa and the accession number is P16235. | |||
TMPY-03191 |
PTH Protein, Human, Recombinant (hFc)
PTH,parathyroid hormone,PTH1 |
Human | HEK293 Cells |
PTH Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 37.9 kDa and the accession number is P01270. | |||
TMPJ-00740 |
PTH Protein, Human, Recombinant
PTH,Parathyrin,Parathyroid Hormone,Parathormone... |
Human | E. coli |
Parathyroid hormone is the most important endocrine regulator of calcium and phosphorus concentration in extracellular fluid. This hormone is secreted from cells of the parathyroid glands and finds its major target cells in bone and kidney. Another hormone, parathyroid hormone-related protein, binds to the same receptor as parathyroid hormone and has major effects on development. Like most other protein hormones, parathyroid hormone is synthesized as a preprohormone. After intracellular processi... | |||
TMPY-03784 |
GPHA2 Protein, Human, Recombinant (His)
GPA2,glycoprotein hormone α 2,A2,ZSIG51,glycoprotei... |
Human | HEK293 Cells |
GPHA2 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 13.1 kDa and the accession number is Q96T91. | |||
TMPJ-00741 |
PTH Protein, Human, Recombinant (His)
Parathyroid hormone,Parathyrin,PTH,Parathormone... |
Human | HEK293 Cells |
Parathyroid hormone (PTH) is a critical hormone in the regulation of Ca++ homeostasis. Parathyroid hormone is the most important endocrine regulator of calcium and phosphorus concentration in extracellular fluid. This hormone is secreted from cells of the parathyroid glands and finds its major target cells in bone and kidney. Another hormone, parathyroid hormone-related protein, binds to the same receptor as parathyroid hormone and has major effects on development. Like most other protein hormon... | |||
TMPH-01848 |
PTHLH Protein, Human, Recombinant (His)
Parathyroid hormone-related protein,PTHLH,Parathyro... |
Human | E. coli |
PTHLH Protein, Human, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 19.7 kDa and the accession number is P12272. | |||
TMPY-03812 |
GPHA2 Protein, Human, Recombinant (mFc)
ZSIG51,glycoprotein hormone α 2,A2,GPA2,glycoprotei... |
Human | HEK293 Cells |
GPHA2 Protein, Human, Recombinant (mFc) is expressed in HEK293 mammalian cells with mFc tag. The predicted molecular weight is 38.1 kDa and the accession number is Q96T91. | |||
TMPY-00091 |
FSH Beta Protein, Human, Recombinant (His)
HH24,FSH β,follicle stimulating hormone, β polypept... |
Human | HEK293 Cells |
FSH Beta Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 13.9 kDa and the accession number is A0A0F7RQE8. | |||
TMPH-02434 |
PTH Protein, Cynomolgus, Recombinant (His & Myc)
Parathyroid hormone,PTH,Parathyrin |
Cynomolgus | E. coli |
PTH elevates calcium level by dissolving the salts in bone and preventing their renal excretion. Stimulates [1-14C]-2-deoxy-D-glucose (2DG) transport and glycogen synthesis in osteoblastic cells. PTH Protein, Cynomolgus, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 16.9 kDa and the accession number is Q9XT35. | |||
TMPH-03348 |
PTH Protein, Rat, Recombinant (His & Myc)
Parathyrin,PTH,Parathyroid hormone |
Rat | E. coli |
PTH elevates calcium level by dissolving the salts in bone and preventing their renal excretion. Stimulates [1-14C]-2-deoxy-D-glucose (2DG) transport and glycogen synthesis in osteoblastic cells. PTH Protein, Rat, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 16.9 kDa and the accession number is Q9XT35. | |||
TMPY-04890 |
FSH Beta Protein, Human, Recombinant (hFc)
follicle stimulating hormone, beta polypeptide,foll... |
Human | HEK293 Cells |
FSH Beta Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 39.2 kDa and the accession number is A0A0F7RQE8. | |||
TMPK-00806 |
GHR/Growth Hormone R Protein, Human, Recombinant (His)
GHR/BP,GH receptor,GHBP,GHR |
Human | HEK293 Cells |
Pegvisomant, a growth hormone receptor (GHR) antagonist, is a well-known drug that was designed to treat acromegaly. However, recent studies have indicated that the GHR is a "moonlighting" protein that may exhibit dual functions based on its localization in the plasma membrane and nucleus. | |||
TMPH-03127 |
GH Protein, Pig, Recombinant (His & Myc)
GH1,Growth hormone,Somatotropin |
Sus scrofa (Pig) | E. coli |
Plays an important role in growth control. Its major role in stimulating body growth is to stimulate the liver and other tissues to secrete IGF-1. It stimulates both the differentiation and proliferation of myoblasts. It also stimulates amino acid uptake and protein synthesis in muscle and other tissues. GH Protein, Pig, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 29.4 kDa and the accession number is P01248. | |||
TMPH-03112 |
GHR Protein, Pig, Recombinant (His)
Growth hormone receptor,GHR,Somatotropin receptor |
Sus scrofa (Pig) | E. coli |
Receptor for pituitary gland growth hormone involved in regulating postnatal body growth. On ligand binding, couples to, and activates the JAK2/STAT5 pathway.; The soluble form (GHBP) acts as a reservoir of growth hormone in plasma and may be a modulator/inhibitor of GH signaling. GHR Protein, Pig, Recombinant (His) is expressed in E. coli expression system with C-6xHis tag. The predicted molecular weight is 30.3 kDa and the accession number is P19756. | |||
TMPH-02440 |
GHR Protein, Rhesus macaque, Recombinant (His)
GHR,Somatotropin receptor,Growth hormone receptor |
Rhesus | E. coli |
Receptor for pituitary gland growth hormone involved in regulating postnatal body growth. On ligand binding, couples to, and activates the JAK2/STAT5 pathway.; The soluble form (GHBP) acts as a reservoir of growth hormone in plasma and may be a modulator/inhibitor of GH signaling. GHR Protein, Rhesus macaque, Recombinant (His) is expressed in E. coli expression system with C-6xHis tag. The predicted molecular weight is 30.2 kDa and the accession number is P79194. | |||
TMPH-03204 |
GHR Protein, Rabbit, Recombinant (His & Myc)
GHR,Somatotropin receptor,Growth hormone receptor |
Rabbit | E. coli |
Receptor for pituitary gland growth hormone involved in regulating postnatal body growth. On ligand binding, couples to, and activates the JAK2/STAT5 pathway.; The soluble form (GHBP) acts as a reservoir of growth hormone in plasma and may be a modulator/inhibitor of GH signaling. GHR Protein, Rabbit, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 34.6 kDa and the accession number is P19941. | |||
TMPH-01348 |
FSHR Protein, Human, Recombinant (His)
Follitropin receptor,FSHR,Follicle-stimulating hormone |
Human | HEK293 Cells |
G protein-coupled receptor for follitropin, the follicle-stimulating hormone. Through cAMP production activates the downstream PI3K-AKT and ERK1/ERK2 signaling pathways. FSHR Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with N-6xHis tag. The predicted molecular weight is 43.5 kDa and the accession number is P23945. | |||
TMPH-00488 |
Glycoprotein hormones alpha chain Protein, Canine, Recombinant (His)
Follicle-stimulating hormone alpha chain,Glycoprote... |
Canine | P. pastoris (Yeast) |
Glycoprotein hormones alpha chain Protein, Canine, Recombinant (His) is expressed in Yeast. | |||
TMPJ-00017 |
GNRH2 Protein, Human, Recombinant (His)
GnRH-Associated Peptide 2,LH-RH II,Gonadoliberin-2,GnRH II,L... |
Human | HEK293 Cells |
Progonadoliberin-2, also known as Progonadoliberin II and GNRH2, belongs to the gonadotropin-releasing hormone family. GNRH2 is specially expressed in midbrain, at significantly higher levels outside the brain (up to 30-fold). GNRH2 can be cleaved into two chains, gonadoliberin-2 and GnRH-associated peptide 2. gonadoliberin-2 regulates reproduction in females by stimulating the secretion of both luteinizing- and follicle-stimulating hormones. The proproteins produce three transcript variants, bu... | |||
TMPH-01347 |
FSHR Protein, Human, Recombinant (E. coli, His)
Follicle-stimulating hormone receptor,Follitropin r... |
Human | E. coli |
G protein-coupled receptor for follitropin, the follicle-stimulating hormone. Through cAMP production activates the downstream PI3K-AKT and ERK1/ERK2 signaling pathways. FSHR Protein, Human, Recombinant (E. coli, His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 44.0 kDa and the accession number is P23945. | |||
TMPH-02685 |
GPHB5 Protein, Mouse, Recombinant (His & Myc)
Glycoprotein hormone beta-5,Thyrostimulin subunit b... |
Mouse | E. coli |
Functions as a heterodimeric glycoprotein hormone with GPHA2 able to bind and activate the thyroid-stimulating hormone receptor (TSHR), leading to increased cAMP production. Plays a central role in controlling thyroid cell metabolism. | |||
TMPH-02684 |
GPHB5 Protein, Mouse, Recombinant (His)
Thyrostimulin subunit beta,Glycoprotein hormone bet... |
Mouse | P. pastoris (Yeast) |
Functions as a heterodimeric glycoprotein hormone with GPHA2 able to bind and activate the thyroid-stimulating hormone receptor (TSHR), leading to increased cAMP production. Plays a central role in controlling thyroid cell metabolism. GPHB5 Protein, Mouse, Recombinant (His) is expressed in yeast with C-6xHis tag. The predicted molecular weight is 13.3 kDa and the accession number is Q812B2. | |||
TMPY-02236 |
PTH1R Protein, Human, Recombinant (His)
PFE,PTHR1,MGC138452,parathyroid hormone 1 receptor,... |
Human | HEK293 Cells |
Parathyroid hormone / parathyroid hormone-related peptide receptor, also known as PTH / PTHrP type I receptor, PTH/PTHr receptor, Parathyroid hormone 1 receptor, PTH1 receptor, PTH1R and PTHR, is a multi-pass membrane protein which belongs to the G-protein coupled receptor 2 family. PTH1R is expressed in most tissues. It is most abundant in kidney, bone and liver. PTH1R is expressed in high levels in bone and kidney and regulates calcium ion homeostasis through activation of adenylate cyclase an... | |||
TMPY-04307 |
GNRH2 Protein, Human, Recombinant (hFc)
LH-RHII,gonadotropin releasing hormone 2,GnRH-II,GN... |
Human | HEK293 Cells |
GNRH2 (Gonadotropin-Releasing Hormone 2) is a Protein Coding gene. This gene is a member of the gonadotropin-releasing hormone (GnRH) gene family. Proteins encoded by members of this gene family are proteolytically cleaved to form neuropeptides which, in part, regulate reproductive functions by stimulating the production and release of the gonadotropins follicle-stimulating hormone (FSH) and luteinizing hormone (LH). 3 alternatively spliced human isoforms have been reported. The second mammalian... | |||
TMPH-00489 |
Glycoprotein hormones alpha chain Protein, Canine, Recombinant (His & Myc)
Follitropin alpha chain,CGA,Luteinizing hormone alp... |
Canine | E. coli |
Glycoprotein hormones alpha chain Protein, Canine, Recombinant (His & Myc) is expressed in E. coli. | |||
TMPH-01087 |
CSH2 Protein, Human, Recombinant (GST & His)
Chorionic somatomammotropin hormone 2,Lactogen,Chor... |
Human | E. coli |
Produced only during pregnancy and is involved in stimulating lactation, fetal growth and metabolism. Does not interact with GHR but only activates PRLR through zinc-induced dimerization. CSH2 Protein, Human, Recombinant (GST & His) is expressed in E. coli expression system with N-6xHis-GST tag. The predicted molecular weight is 53.8 kDa and the accession number is P0DML3. | |||
TMPH-02788 |
Muellerian-inhibiting factor/AMH Protein, Mouse, Recombinant (E. coli, His)
Amh,Anti-Muellerian hormone,Muellerian-inhibiting s... |
Mouse | E. coli |
Muellerian-inhibiting factor/AMH Protein, Mouse, Recombinant (E. coli, His) is expressed in E. coli. | |||
TMPH-00283 |
Lutropin subunit beta Protein, Bovine, Recombinant (His)
LHB,Lutropin subunit beta,Lutropin beta chain,Luteinizing |
Bovine | E. coli |
Promotes spermatogenesis and ovulation by stimulating the testes and ovaries to synthesize steroids. Lutropin subunit beta Protein, Bovine, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 17.0 kDa and the accession number is P04651. | |||
TMPH-00495 |
Lutropin subunit beta Protein, Canine, Recombinant (His)
Luteinizing hormone subunit beta,Lutropin subunit b... |
Canine | E. coli |
Lutropin subunit beta Protein, Canine, Recombinant (His) is expressed in E. coli. | |||
TMPY-04127 |
CIp4 Protein, Human, Recombinant (His)
CIP4,thyroid hormone receptor interactor 10,STOT,ST... |
Human | Baculovirus Insect Cells |
CIp4 Protein, Human, Recombinant (His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 64 kDa and the accession number is Q15642-2. | |||
TMPH-02608 |
Corticoliberin Protein, Mouse, Recombinant (His & KSI)
Crh,CRF,Corticotropin-releasing hormone,Gm1347,Cort... |
Mouse | E. coli |
Hormone regulating the release of corticotropin from pituitary gland. Induces NLRP6 in intestinal epithelial cells, hence may influence gut microbiota profile. | |||
TMPH-02787 |
Muellerian-inhibiting factor/AMH Protein, Mouse, Recombinant (His)
Anti-Muellerian hormone,Amh,Muellerian-inhibiting s... |
Mouse | P. pastoris (Yeast) |
Muellerian-inhibiting factor/AMH Protein, Mouse, Recombinant (His) is expressed in Yeast. | |||
TMPH-00504 |
Bursicon Protein, Drosophila melanogaster, Recombinant (GST)
Bursicon,Cuticle-tanning hormone,Bursicon subunit a... |
Fruit fly | E. coli |
Final heterodimeric neurohormone released at the end of the molting cycle, involved in the sclerotization (tanning) of the insect cuticle, melanization and wing spreading. Heterodimer specifically activates the G protein-coupled receptor rk. Bursicon Protein, Drosophila melanogaster, Recombinant (GST) is expressed in E. coli expression system with N-GST tag. The predicted molecular weight is 42.5 kDa and the accession number is Q9VD83. | |||
TMPY-06821 |
THRB Protein, Human, Recombinant (His)
THRB1,GRTH,THR1,ERBA2,C-ERBA-2,THRB2,thyroid hormone |
Human | E. coli |
Thyroid hormone receptor beta (THRB), also known as TRbeta and NR1A2, belongs to the nuclear hormone receptor family. Featuring an N-terminal transactivation domain, a central DNA-binding domain, and a hormone/ligand-binding domain, THRB isoform 1/2 expression localizes predominately to the liver and pituitary, respectively. THRB regulates the feedback of T3-dependent thyrotropin-stimulating hormone (TSH) transcription in the pituitary by binding to thyroid hormone (TH) response elements present... | |||
TMPH-03387 |
TSHB Protein, Rat, Recombinant (His & Myc)
Thyrotropin subunit beta,Thyroid-stimulating hormone |
Rat | P. pastoris (Yeast) |
Indispensable for the control of thyroid structure and metabolism. TSHB Protein, Rat, Recombinant (His & Myc) is expressed in yeast with N-6xHis and C-Myc tag. The predicted molecular weight is 16.4 kDa and the accession number is P04652. | |||
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Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
TMIJ-0268 |
Relugolix-d6
|
||
Relugolix-d6 是 Relugolix 的氘代化合物。Relugolix 的 CAS 号为 737789-87-6。Relugolix 是口服有活性的非肽性促性腺激素释放激素的拮抗剂。同 TAK-013 相比,它对人和猴子的受体具有高亲和力和强拮抗活性,它们的IC50值分别为0.33 nM和0.32 nM。它可用于研究性激素依赖性疾病,如子宫肌瘤、子宫内膜异位症、前列腺癌等。 | |||
T12363 |
Paricalcitol-D6
|
Others | Others |
Paricalcitol-D6 is the deuterated form of Paricalcitol, which is used for the prevention and treatment of secondary hyperparathyroidism (excessive secretion of parathyroid hormone) associated with chronic renal failure. | |||
T36383 |
L-Thyroxine-13C9,15N
L-Thyroxine-13C9,15N |
||
L-Thyroxine-13C9,15N is intended for use as an internal standard for the quantification of L-thyroxine by GC- or LC-MS. L-Thyroxine is a synthetic form of the thyroid hormone thyroxine. In vivo, L-thyroxine (0.9 and 2.7 μg) inhibits synthesis and release of thyrotropin induced by thyrotropin-releasing hormone from the anterior pituitary in mice. It also reverses decreases in levels of circulating thymic serum factor (FTS) and the number of T rosette-forming cells in an old age-induced mouse mode... | |||
TMID-0131 |
Norethindrone-2,2,4,6,6,10-d6
|
||
Norethindrone-2,2,4,6,6,10-d6 是 Norethindrone 的氘代化合物。Norethindrone 的 CAS 号为 68-22-4。Norethindrone 是孕激素,能够用于子宫内膜异位症、由激素水平异常引起的子宫出血和继发性闭经的研究。 | |||
TMIJ-0382 |
Norethindrone (Ethynyl-13C2)
|
||
Norethindrone (Ethynyl-13C2) 是 Norethindrone 的 13C 的标记化合物。Norethindrone 的 CAS 号为 68-22-4。Norethindrone 是孕激素,能够用于子宫内膜异位症、由激素水平异常引起的子宫出血和继发性闭经的研究。 | |||
T11995 |
Melatonin-d4
N-Acetyl-5-methoxytryptamine D5,Melatonin D5,褪黑素 D5 |
Others | Others |
Melatonin D5, a deuterium-labeled version of melatonin, is a hormone produced by the pineal gland, known for its role as a selective ATF-6 inhibitor that promotes apoptosis in human hepatoma cells via COX-2 downregulation. Additionally, it activates melatonin receptors and exhibits antioxidative and anti-inflammatory properties. | |||
TMID-0129 |
Megestrol-d5
|
||
Megestrol-d5 是 Megestrol 的氘代化合物。Megestrol 的 CAS 号为 3562-63-8。 | |||
TMID-0128 |
Megestrol-d3
|
||
Megestrol-d3 是 Megestrol 的氘代化合物。Megestrol 的 CAS 号为 3562-63-8。 | |||
TMID-0059 |
DL-Epinephrine-d3
|
||
DL-Epinephrine-d3 是 DL-Epinephrine 的氘代化合物。DL-Epinephrine 的 CAS 号为 329-65-7。DL-Adrenalin 是一种激素和神经递质。 | |||
TMIJ-0056 |
DL-Epinephrine-d6
|
||
DL-Epinephrine-d6 是 DL-Epinephrine 的氘代化合物。DL-Epinephrine 的 CAS 号为 329-65-7。DL-Adrenalin 是一种激素和神经递质。 | |||
TMID-0111 |
11-Deoxycortisol-2,2,4,6,6-d5
|
||
11-Deoxycortisol-2,2,4,6,6-d5 是 11-Deoxycortisol 的氘代化合物。11-Deoxycortisol 的 CAS 号为 152-58-9。Cortodoxone是糖皮质类固醇激素,能够氧化为皮质醇。 | |||
TMIJ-0172 |
Mifepristone-d6
|
||
Mifepristone-d6 是 Mifepristone 的氘代化合物。Mifepristone 的 CAS 号为 84371-65-3。Mifepristone 是一种黄体酮受体和糖皮质激素受体拮抗剂,在体外实验中的IC50值分别为 0.2 nM 和 2.6 nM。 | |||
TMID-0133 |
Medroxyprogesterone-d3
|
||
Medroxyprogesterone-d3 是 Medroxyprogesterone 的氘代化合物。Medroxyprogesterone 的 CAS 号为 520-85-4。Medroxyprogesterone 是一种合成的人孕酮变体,是孕酮受体激动剂,用于治疗肾癌。在兽医实践中用作发情调节剂。 | |||
TMIJ-0263 |
Dienogest-d6
|
||
Dienogest-d6 是 Dienogest 的氘代化合物。Dienogest 的 CAS 号为 65928-58-7。Dienogest是一种孕酮受体激动剂,作用于子宫内膜异位,有口服的子宫内膜活性。 | |||
TMID-0135 |
Melengestrol acetate-d3
|
||
Melengestrol acetate-d3 是 Melengestrol acetate 的氘代化合物。Melengestrol acetate 的 CAS 号为 2919-66-6。Melengestrol acetate 是孕酮的衍生物,充当皮质类固醇激素。 Melengestrol acetate 可以促进月经活动和妊娠维持的子宫内膜增殖延迟。 | |||
TMID-0261 |
Indole-2,4,5,6,7-d5-3-acetic Acid
|
||
Indole-2,4,5,6,7-d5-3-acetic Acid 是 Indole-3-acetic Acid 的氘代化合物。Indole-3-acetic Acid 的 CAS 号为 87-51-4。3-Indoleacetic acid 是常见的天然植物生长激素。它可以诱导植物细胞的伸长和分裂。 | |||
TMID-0159 |
Indole-3-Acetic-d2 Acid
|
||
Indole-3-Acetic-d2 Acid 是 Indole-3-Acetic Acid 的氘代化合物。Indole-3-Acetic Acid 的 CAS 号为 87-51-4。3-Indoleacetic acid 是常见的天然植物生长激素。它可以诱导植物细胞的伸长和分裂。 | |||
TMIJ-0265 |
Homovanillic Acid-13C-d3
|
||
Homovanillic Acid-13C-d3 是 Homovanillic Acid 的 13C 和氘代化合物。Homovanillic Acid 的 CAS 号为 306-08-1。Homovanillic acid 是一种多巴胺代谢物,它与乳糜泻、生长激素缺乏、芳香族氨基酸脱羧酶缺乏症以及脂联素还原酶缺乏症相关。 | |||
TMID-0137 |
Pregnenolone-d4
|
||
Pregnenolone-d4 是 Pregnenolone 的氘代化合物。Pregnenolone 的 CAS 号为 145-13-1。Pregnenolone 是一种由胆固醇合成的内源性类固醇激素,用于治疗阿尔茨海默病。它是大麻素CB1受体的信号传导特异性抑制剂,抑制由CB1受体介导的四氢大麻酚 的作用。它也是TRPM3通道激活剂,也可弱激活TRPM1通道。 | |||
TMIH-0550 |
Taltirelin-13C-d3
|
||
Taltirelin-13C-d3 是 Taltirelin 的 13C 和氘代化合物。Taltirelin 的 CAS 号为 103300-74-9。Taltirelin 是促甲状腺激素释放激素受体(TRH-R)超激动剂(IC50:910 nM),能够刺激细胞溶质Ca2+浓度增加 (Ca2+释放) (EC50:36 nM)。 | |||
TMIJ-0193 |
Hydrocortisone-d4
|
||
Hydrocortisone-d4 是 Hydrocortisone 的氘代化合物。Hydrocortisone 的 CAS 号为 50-23-7。Hydrocortisone 是肾上腺皮质分泌的糖皮质激素。 | |||
TMID-0157 |
Indole-3-butyric acid-d2
|
||
Indole-3-butyric acid-d2 是 Indole-3-butyric acid 的氘代化合物。Indole-3-butyric acid 的 CAS 号为 133-32-4。3-Indolebutyric acid 是一种植物生长素。 它能够促进草本植物和木本观赏植物生根,并用于提高果实率。 | |||
TMID-0156 |
Indole-2,4,5,6,7-d5-3-acetic-2,2-d2 Acid
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Indole-2,4,5,6,7-d5-3-acetic-2,2-d2 Acid 是 Indole-3-acetic Acid 的氘代化合物。Indole-3-acetic Acid 的 CAS 号为 87-51-4。3-Indoleacetic acid 是常见的天然植物生长激素。它可以诱导植物细胞的伸长和分裂。 | |||
TMIH-0089 |
Androstenedione-d7
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Androstenedione-d7 是 Androstenedione 的氘代化合物。Androstenedione 的 CAS 号为 560-62-3。9-hydroxy-4-androstene-3,17-dione 是一种类固醇激素,具有抗肿瘤活性,可以抑制多种癌症细胞的生长,包括乳腺癌、前列腺癌和肺癌细胞。 | |||
TMID-0229 |
Cortisol-1,2-d2
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Cortisol-1,2-d2 是 Cortisol 的氘代化合物。Cortisol 的 CAS 号为 50-23-7。Hydrocortisone 是肾上腺皮质分泌的糖皮质激素。 | |||
TMID-0057 |
(4-Hydroxy-3-methoxyphenyl)acetic-2,2-d2 Acid
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(4-Hydroxy-3-methoxyphenyl)acetic-2,2-d2 Acid 是 (4-Hydroxy-3-methoxyphenyl)acetic Acid 的氘代化合物。(4-Hydroxy-3-methoxyphenyl)acetic Acid 的 CAS 号为 306-08-1。Homovanillic acid 是一种多巴胺代谢物,它与乳糜泻、生长激素缺乏、芳香族氨基酸脱羧酶缺乏症以及脂联素还原酶缺乏症相关。 | |||
TMID-0091 |
BISPHENOL A-d16
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BISPHENOL A-d16 是 BISPHENOL-A 的氘代化合物。BISPHENOL-A 的 CAS 号为 80-05-7。Bisphenol A 是酚类有机合成化合物,广泛用于环氧树脂和聚碳酸酯塑料的生产。它是生殖、发育和全身毒性物质,常被归类为内分泌干扰物。它与许多疾病有关,包括呼吸系统疾病、心血管疾病、糖尿病、肾脏疾病、肥胖和生殖障碍。 | |||
TMID-0248 |
Triamcinolone acetonide-d6
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Triamcinolone acetonide-d6 是 Triamcinolone acetonide 的氘代化合物。Triamcinolone acetonide 的 CAS 号为 76-25-5。Triamcinolone acetonide 是皮质类固醇。 它是皮质类固醇激素受体激动剂。 它是抗炎糖皮质激素,局部用于治疗各种皮肤疾病。它的有效性是 prednisone 的八倍。 | |||
TMID-0092 |
BISPHENOL-A-3,3',5,5'-d4
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BISPHENOL-A-3,3',5,5'-d4 是 BISPHENOL-A 的氘代化合物。BISPHENOL-A 的 CAS 号为 80-05-7。Bisphenol A 是酚类有机合成化合物,广泛用于环氧树脂和聚碳酸酯塑料的生产。它是生殖、发育和全身毒性物质,常被归类为内分泌干扰物。它与许多疾病有关,包括呼吸系统疾病、心血管疾病、糖尿病、肾脏疾病、肥胖和生殖障碍。 | |||
TMID-0104 |
L-Thyroxine-13C6
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L-Thyroxine-13C6 是 L-Thyroxine 的 13C 的标记化合物。L-Thyroxine 的 CAS 号为 51-48-9。L-Thyroxine (T4)是一种合成的甲状腺激素,用于甲状腺功能减退症的研究。在DIO 酶作用下, L-Thyroxine (T4)转化成具有生物特性的三碘甲状腺氨酸 (T3)。 | |||
TMID-0093 |
BISPHENOL-A-2,2',6,6'-d4
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BISPHENOL-A-2,2',6,6'-d4 是 BISPHENOL-A 的氘代化合物。BISPHENOL-A 的 CAS 号为 80-05-7。Bisphenol A 是酚类有机合成化合物,广泛用于环氧树脂和聚碳酸酯塑料的生产。它是生殖、发育和全身毒性物质,常被归类为内分泌干扰物。它与许多疾病有关,包括呼吸系统疾病、心血管疾病、糖尿病、肾脏疾病、肥胖和生殖障碍。 | |||
TMIJ-0374 |
L-Leucine-d3
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L-Leucine-d3 是 L-Leucine 的氘代化合物。L-Leucine 的 CAS 号为 61-90-5。L-Leucine 是必需的支链氨基酸,能够激活mTOR信号通路。 | |||
TMID-0090 |
BISPHENOL-A-2,2',3,3',5,5',6,6'-d8
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BISPHENOL-A-2,2',3,3',5,5',6,6'-d8 是 BISPHENOL-A 的氘代化合物。BISPHENOL-A 的 CAS 号为 80-05-7。Bisphenol A 是酚类有机合成化合物,广泛用于环氧树脂和聚碳酸酯塑料的生产。它是生殖、发育和全身毒性物质,常被归类为内分泌干扰物。它与许多疾病有关,包括呼吸系统疾病、心血管疾病、糖尿病、肾脏疾病、肥胖和生殖障碍。 | |||
TMIJ-0081 |
L-Leucine-d10
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L-Leucine-d10 是 L-Leucine 的氘代化合物。L-Leucine 的 CAS 号为 61-90-5。L-Leucine 是必需的支链氨基酸,能够激活mTOR信号通路。 | |||
TMID-0115 |
Dehydroepiandrosterone-2,2,3,4,4,6-d6
DHEA-d6 |
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Dehydroepiandrosterone-2,2,3,4,4,6-d6 是 Dehydroepiandrosterone 的氘代化合物。Dehydroepiandrosterone 的 CAS 号为 53-43-0。Dehydroepiandrosterone 是一种类固醇激素。它通过多种信号传导途径介导其作用,并通过转化成雄激素和雌激素衍生物(例如,雄激素,雌激素,7α和7β DHEA (Prasterone),以及7α和7β表雄甾酮衍生物)在特异性受体上起作用。 | |||
T70882 |
Orlistat-d3
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Orlistat-d3 is intended for use as an internal standard for the quantification of orlistat by GC- or LC-MS. Orlistat is a digestive lipase inhibitor. It inhibits diacylglycerol lipase α (DAGLα), DAGLβ, α/β-hydrolase domain-containing protein 12 (ABHD12), ABHD16A, and platelet-activating factor acetylhydrolase (PAF-AH; IC50s = 0.06, 0.1, 0.08, 0.03, and 0.05 µM, respectively), as well as pancreatic lipase and hormone-sensitive lipase (IC50s = 0.65 and 2.1 µg/ml, respectively) but does not inhibit... |