322
83
2
22
9
Cat. No. | Product Name | Form | Specificity Of Inhibition |
---|---|---|---|
C0051 |
Penicillin-Streptomycin Solution (100×), Sterile
青霉素-链霉素双抗溶液(100×),灭菌 |
Solution in bottle | |
C0052 |
Penicillin-Streptomycin-Amphotericin B Solution (100×), Sterile
青霉素-链霉素-两性霉素B三抗溶液(100×),灭菌 |
Solution in bottle |
Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T14391 |
Azidamfenicol
|
Antibacterial; Antibiotic | Microbiology/Virology |
Azidamfenicol 抑制核糖体肽基转移酶,Ki 为 22 µM。Azidamfenicol 是一种广谱氯霉素类抗生素。 | |||
T9680 |
Irloxacin
|
Antibacterial | Microbiology/Virology |
Irloxacin 是一种口服活性的喹诺酮类抗菌剂,在酸性条件下具有更强大的活性。在体外,Irloxacin 对革兰氏阳性菌和革兰氏阴性菌都具有良好的抗菌谱。 | |||
T20525 |
Chloramphenicol palmitate
|
Antibacterial; Antibiotic | Microbiology/Virology |
Chloramphenicol palmitate 是一种广谱抗生素,对革兰氏阳性和革兰氏阴性细菌具有活性。 Chloramphenicol palmitate 可用于在含有氯霉素抗性基因的转化细胞中作为细菌选择剂的研究。 | |||
T4998L |
Cefpodoxime (free acid)
|
Others | Others |
Cefpodoxime (free acid) 是一种口服的第三代头孢菌素抗生素。除铜绿假单胞菌、肠球菌和脆弱拟杆菌外,它对大多数革兰氏阳性和革兰氏阴性微生物均有效。 | |||
T19858 |
Brodimoprim
|
DHFR; Antibacterial | Cell Cycle/Checkpoint; DNA Damage/DNA Repair; Metabolism; Microbiology/Virology |
Brodimoprim 是甲氧苄啶的一种类似物,是口服有效的二氢叶酸还原酶抑制剂,对广谱革兰氏阴性和革兰氏阳性细菌具有高度的抑制作用。 | |||
T1008 |
Cephalexin
头孢氨苄,Cefalexin,Cephacillin |
Antibacterial; Antibiotic | Microbiology/Virology |
Cephalexin (Cephacillin) 是一种强口服活性的头孢菌素抗生素。它通过破坏细菌细胞壁的生长来杀死革兰氏阳性和一些革兰氏阴性细菌。它可研究肺炎、链球菌性咽喉炎、细菌性心内膜炎等。 | |||
TP1444 |
Magainin 2
蛙皮素 2 |
Antibacterial; Antibiotic; Antifungal | Microbiology/Virology |
Magainin 2是从非洲爪蟾皮肤中分离得到的一种抗菌肽。它对许多革兰氏阴性和革兰氏阳性细菌显示出抗生素活性,对原生动物也有活性。它通过优先与细菌膜中丰富的阴离子磷脂相互作用而发挥细胞毒性作用。 | |||
T6582 |
Mezlocillin Sodium
美洛西林钠,Baycipen |
Antibacterial; Antibiotic | Microbiology/Virology |
Mezlocillin Sodium (Baycipen) 是一种青霉素 β-内酰胺类抗生素,用于治疗由易感染微生物引起的细菌感染。 | |||
T3117 |
Marbofloxacin
马波沙星,Marbofloxacine,Zeniquin,Marbocyl |
Topoisomerase; Antibacterial; Antibiotic | DNA Damage/DNA Repair; Microbiology/Virology |
Marbofloxacin (Zeniquin) 是一种具有口服活性的氟喹诺酮类广谱抗菌剂。它可研究革兰氏阳性和革兰氏阴性细菌以及支原体引起的感染。 | |||
T5006 |
Flucloxacillin sodium
氟氯西林钠,floxacillin sodium |
Antibacterial; Antibiotic | Microbiology/Virology |
Flucloxacillin sodium (floxacillin sodium) 是一种高活性抗生素,抑制革兰氏阳性和革兰氏阴性菌。 | |||
T0116 |
Balofloxacin
|
DNA gyrase; Antibacterial; Antibiotic | DNA Damage/DNA Repair; Microbiology/Virology |
Balofloxacin 是一种具有口服活性的氟喹诺酮类抗生素,可通过干扰 DNA 促旋酶来抑制细菌 DNA 的合成,对革兰氏阴性,革兰氏阳性和厌氧菌具有广谱抗菌活性。它可研究呼吸道,肠道和泌尿道感染。 | |||
T0396 |
Pipemidic acid
吡哌酸,Acido pipemidico |
Antibacterial; Antibiotic | Microbiology/Virology |
Pipemidic acid (Acido pipemidico) 是一种新型抗菌剂,对革兰氏阴性菌和某些革兰氏阳性细菌具有活性,可研究肠道、泌尿和胆道感染。 | |||
T9066 |
Merafloxacin
CI 934 |
SARS-CoV | Microbiology/Virology |
Merafloxacin (CI 934) 是一种氟喹诺酮类抗菌药物,也被确定为 SARS-CoV-2 的 1 PRF 抑制剂。它对革兰氏阳性菌和革兰氏阴性菌具有体外活性。 | |||
T19794 |
Temafloxacin
替马沙星,Omniflox |
Antibiotic | Microbiology/Virology |
Temafloxacin (Omniflox) 是一种喹诺酮类广谱抗菌剂,对革兰氏阳性菌、革兰氏阴性菌和厌氧菌均有效。 | |||
T40475 |
Ceftobiprole medocaril
BAL5788,头孢比普酯 |
Antibacterial | Microbiology/Virology |
Ceftobiprole medocaril (BAL5788) 是 Ceftobiprole 的前药。Ceftobiprole 是一种广谱的头孢菌素,对耐甲氧西林金黄色葡萄球菌具有活性。 | |||
TQ0077 |
Ceftobiprole
Ro 63-9141,BAL 9141,头孢吡普 |
Antibacterial | Microbiology/Virology |
Ceftobiprole (Ro 63-9141) 是一种广谱头孢菌素,对甲氧西林耐受的金黄色葡萄球菌的MIC90值为 2 μg/mL。 | |||
T5189 |
Omadacycline
PTK 0796,Amadacycline |
ribosome; Antibacterial; Antibiotic | Microbiology/Virology |
Omadacycline (Amadacycline) 是一种具有口服活性的氨基甲基环素抗菌剂,是四环素类抗生素。它与 30S 核糖体亚基结合,抑制细菌蛋白质合成。它可用于研究急性细菌性皮肤和皮肤结构感染,感染性肺炎和尿路感染。 | |||
T0921 |
Sulfabenzamide
Sultrin,N-Sulfanilylbenzamide,苯甲酰磺胺 |
Antibacterial; Antibiotic; Autophagy | Autophagy; Microbiology/Virology |
Sulfabenzamide (N-Sulfanilylbenzamide) 是一种磺胺类抗菌剂,可单独使用或与磺胺噻唑和磺胺乙酰胺一起用作阴道内的局部抗菌制剂。 | |||
T0274 |
Cinoxacin
西诺沙星,Compound 64716 |
Topoisomerase; Antibacterial; Antibiotic | DNA Damage/DNA Repair; Microbiology/Virology |
Cinoxacin (Compound 64716) 是一种喹诺酮类的合成抗生素, 与Oxolinic acid 和 Nalidixic acid 活性相似。 | |||
T7865 |
Danofloxacin
达氟沙星,达诺沙星,Danofloxacino,Danofloxacin free base,Danofloxacine |
Others; DNA/RNA Synthesis; Antibacterial; Antibiotic | Cell Cycle/Checkpoint; DNA Damage/DNA Repair; Microbiology/Virology; Others |
Danofloxacin (Danofloxacin free base) free base 是一种具有口服活性第三代氟喹诺酮抗菌剂,对大多数革兰氏阴性和革兰氏阳性细菌,支原体和衣原体物种具有广谱的活性,并通过抑制细菌的 DNA 回转酶发挥抗菌作用。它可用于牛,猪和鸡呼吸道疾病的研究。 | |||
T0133 |
Cefdinir
FK-482,头孢地尼,CI-983,PD 134393 |
Glutathione Peroxidase; Antibacterial; Antibiotic | Metabolism; Microbiology/Virology |
Cefdinir (FK-482) 是头孢菌素类中的一种半合成广谱抗生素,对几种革兰氏阴性和革兰氏阳性细菌引起的感染有效。它可研究耳,鼻窦,喉咙和皮肤的常见细菌感染。 | |||
T1190 |
Cefmenoxime hydrochloride
Cefmenoxime hemihydrochloride,SCE-1365 hemihydrochloride,盐酸头孢甲肟 |
Antibacterial; Antibiotic; Antifection | Microbiology/Virology |
Cefmenoxime hydrochloride (Cefmenoxime hemihydrochloride) 是一种头孢类抗生素,可通过静脉内或肌肉内给药。 它对大多数常见的革兰氏阳性和革兰氏阴性微生物有活性,是一种肠杆菌科抑制剂,并且对 β-内酰胺酶的水解具有高度抗性。 | |||
T0195 |
Secnidazole
RP-14539,PM-185184,塞克硝唑 |
Antibiotic; Parasite | Microbiology/Virology |
Secnidazole (PM-185184) 是一种具有口服活性唑类抗生素,半衰期比甲硝唑更长。它有潜力研究细菌性阴道病。 | |||
T12004 |
Meropenem trihydrate
美罗培南三水合物,SM 7338 trihydrate |
Antibacterial; Antibiotic | Microbiology/Virology |
Meropenem trihydrate (SM 7338 trihydrate) 是一种碳青霉烯抗生素,具有广谱抗菌活性。它对敏感和耐药的杜克氏杆菌 (MIC 值为 0.015-0.12 mg/mL), 淋病奈瑟氏球菌 (MIC 值为 0.02-0.06 mg/mL)和流感嗜血杆菌 (MIC 值为 0.03-0.12 mg/mL) 具有活性。 | |||
T6438 |
Cefoselis Sulfate
FK 037 Sulfate,FK-037,硫酸头孢噻利 |
Antibacterial; Antibiotic | Microbiology/Virology |
Cefoselis Sulfate (FK 037 Sulfate) 是一种头孢菌素 β-内酰胺抗生素。它对多种革兰氏阳性和革兰氏阴性生物均表现出良好的活性。它可以透过血脑屏障。 | |||
T73997 |
Anti gram-positive/negative bacteria agent 1
|
Others | Others |
Anti gram-positive/negative bacteria agent 1 是一种含有基于MECAM的人工铁载体的抗生素化合物。 | |||
T1000L |
Chlorhexidine diacetate
醋酸氯己定,Hibitane diacetate,Chlorhexidine Acetate,Bactigras |
CAT; Antibacterial; Antibiotic; Antifection | Microbiology/Virology; oxidation-reduction |
Chlorhexidine diacetate (Bactigras) 是一种双胍类杀菌剂,能快速消灭革兰氏阳性菌和革兰氏阴性菌。它也用作漱口水以防止口腔菌斑。 | |||
T0788L |
Spectinomycin dihydrochloride pentahydrate
盐酸大观霉素五水合物,Trobicin,Spectogard,Spectinomycin hydrochloride hydrate |
ribosome; Antibacterial; Antibiotic | Microbiology/Virology |
Spectinomycin dihydrochloride pentahydrate (Spectogard) 是一种广谱氨基环糊精抗生素,可以抑制多种革兰氏阳性和革兰氏阴性生物的生长。 | |||
T0717L |
Enoxacin
依诺沙星,NSC 629661,AT 2266,Pd107779,CI 919 |
DNA/RNA Synthesis; Topoisomerase; Antibacterial; Antibiotic | Cell Cycle/Checkpoint; DNA Damage/DNA Repair; Microbiology/Virology |
Enoxacin (NSC-629661) 是一种可干扰DNA 复制的氟喹诺酮,抑制细菌 DNA 促旋酶 (IC50=126 µg/ml) 和拓扑异构酶 IV (IC50=26.5 µg/ml)。它是特异性癌症生长抑制剂,可有效抑制革兰氏阳性和阴性细菌。 | |||
T1616 |
Cefotiam hydrochloride
盐酸头孢替安,Pansporin,SCE-963 hydrochloride,Pansporine,头孢替安盐酸盐,Cefotiam dihydrochloride,Halospor |
Antibacterial; Antibiotic | Microbiology/Virology |
Cefotiam hydrochloride (SCE-963 hydrochloride) 是一种肠外头孢菌素类广谱抗生素,对革兰氏阳性菌和革兰氏阴性菌有活性。 | |||
T5394 |
Prulifloxacin
AF 3012,Pruvel,NM441,普卢利沙星 |
Topoisomerase; Antibacterial; Antibiotic | DNA Damage/DNA Repair; Microbiology/Virology |
Prulifloxacin (NM441) 是一种口服有效的氟喹诺酮抗生素 ,对革兰氏阳性和阴性细菌具有广泛活性。它是噻唑喹啉羧酸衍生物 Ulifloxacin 的前药。它有潜力用于下尿路感染和慢性支气管炎。 | |||
T0199 |
Cephradine
Anspor,Cephradin,Velosef,SQ-11436,Sefril,头孢拉定 |
TOPK; Antibacterial; Antibiotic | MAPK; Microbiology/Virology |
Cephradine (Anspor) 是广谱口服活性头孢菌素。它对革兰氏阳性和革兰氏阴性病原体都有活性。它已用于泌尿生殖系统、胃肠道和呼吸道感染以及皮肤和软组织感染的研究。它通过直接抑制TOPK 抑制太阳紫外线诱导的皮肤炎症。 | |||
T3125 |
Amikacin sulfate
Amikacin Sulfate Salt,阿米卡霉素硫酸,硫酸阿米卡星 |
ribosome; Antibacterial; Antibiotic | Microbiology/Virology |
Amikacin sulfate 是一种氨基糖苷类抗生素,也是卡那霉素的半合成类似物。它具有杀菌作用,直接作用于 30S 和 50S 细菌核糖体亚基,可抑制蛋白质合成。它抑制大多数革兰氏阴性细菌,还抑制易感诺卡氏菌和非结核分枝杆菌引起的感染。 | |||
T83705 |
BING TFA
Blocker of Inter-membrane Stress Responses of Gram-negative Bacteria |
||
BING是一种来源于日本稻田鱼(O. laptipes)的抗菌肽,由液泡蛋白质分选相关蛋白13D样(Vps13D)衍生而来。对包括耐甲氧西林的金黄色葡萄球菌(MRSA; MICs = 4-64 µg/ml)在内的各种革兰氏阴性和革兰氏阳性细菌都有活性。与氨苄西林、阿莫西林和新霉素共同使用时,对抗铜绿假单胞菌(P. aeruginosa)表现出协同效应,并能抑制大肠杆菌(E. coli)对卡那霉素和氨苄西林的抗药性发展。在体内,BING提高了被鳗弧菌(E. tarda)感染的O. laptipes的生存率。 | |||
T6706 |
Ticarcillin sodium
Ticarpen hydrate,Aerugipen hydrate,替卡西林单钠盐单水合物,BRL 2288,AB 2288,Monapen |
Others; Antibacterial; Antibiotic | Microbiology/Virology; Others |
Ticarcillin sodium (Aerugipen hydrate) 主要用于抗革兰氏阴性菌, 也能用于研究嗜麦芽感染。 | |||
T16028 |
IMB-XH1
Mcl1-IN-2,7-[(2-吡啶基氨基)-2-噻吩基甲基]-8-喹啉醇 |
BCL; Antibacterial | Apoptosis; Microbiology/Virology |
IMB-XH1 (Mcl1-IN-2) 是一种骨髓细胞因子 1 抑制剂。它也是非竞争性的 Delhi metallo-β-lactamase(NDM-1) 抑制剂。它对金属 β-内酰胺酶 NDM-1,IMP-4,ImiS 和 L1 的 IC50值分别为 0.4637 μM,3.980 μM,0.2287 μM 和 1.158 μM。 | |||
T1223 |
Ceftriaxone sodium hydrate
Ceftriaxone Sodium Trihydrate,头孢曲松钠,Ceftriaxone disodium hemiheptahydrate,头孢曲松钠水合物,Ceftriaxone sodium |
Others; Antibacterial; Antibiotic | Microbiology/Virology; Others |
Ceftriaxone sodium hydrate 是一种头孢菌素类抗生素,对革兰氏阳性和革兰氏阴性菌均有活性。它具有抗炎和抗氧化作用。 | |||
T0717 |
Enoxacin hydrate
CI-919 hydrate,Enoxacin Sesquihydrate,依诺沙星半水合物,AT-2266 hydrate,依诺沙星倍半水合物 |
DNA gyrase; DNA/RNA Synthesis; Topoisomerase; Antibacterial; Antibiotic | Cell Cycle/Checkpoint; DNA Damage/DNA Repair; Microbiology/Virology |
Enoxacin hydrate (AT-2266 hydrate) 是氟喹诺酮,可干扰DNA 复制,抑制细菌 DNA 促旋酶 (IC50=126 µg/ml) 和拓扑异构酶 IV (IC50=26.5 µg/ml)。它是特异性癌症生长抑制剂,抑制革兰氏阳性和阴性细菌。 | |||
T6382 |
Amikacin disulfate
硫酸阿米卡星,Pierami,阿米卡星硫酸盐,BAY-416651 sulfate,BB-K8,Amikacin sulfate |
Antibacterial; Antibiotic | Microbiology/Virology |
Amikacin disulfate (BAY-416651 sulfate) 是氨基糖苷类抗生素,也是卡那霉素的半合成类似物。它具有杀菌作用,直接作用于 30S 和 50S 细菌核糖体亚基,可抑制蛋白质合成。它对大多数革兰氏阴性细菌都有效。它还抑制易感诺卡氏菌和非结核分枝杆菌引起的感染。 | |||
T6383 |
Amikacin hydrate
阿米卡星水合物,BAY416651 hydrate |
Others; Antibacterial; Antibiotic | Microbiology/Virology; Others |
Amikacin hydrate (BAY416651 hydrate) 是氨基糖苷类抗生素,也是卡那霉素的半合成类似物。它具有杀菌作用,直接作用于 30S 和 50S 细菌核糖体亚基,可抑制蛋白质合成。它还抑制易感诺卡氏菌和非结核分枝杆菌引起的感染。 | |||
T20774 |
Sarafloxacin
A-56620,A 56620,A56620,沙拉沙星 |
Antibacterial; Antibiotic | Microbiology/Virology |
Sarafloxacin (A56620) 对革兰氏阳性菌和革兰氏阴性菌具有抗菌活性。 | |||
T8352 |
Phanquinone
|
Antibacterial | Microbiology/Virology |
Phanquinone 对广泛的革兰氏阳性和革兰氏阴性生物具有活性。 | |||
T11315 |
Fosmidomycin sodium salt
FR-31564 sodium salt |
Antibiotic; Parasite | Microbiology/Virology |
Fosmidomycin sodium salt (FR-31564 sodium salt) 是一种抗感染类抗生素,具有抗疟疾活性,抑制革兰氏阴性菌和革兰氏阳性菌。 | |||
T22314 |
Doripenem
|
Antibacterial; Antibiotic | Microbiology/Virology |
Doripenem 是对革兰氏阳性菌、阴性菌和厌氧菌有效的β-内酰胺广谱抗生素。 | |||
T0425 |
Pefloxacin Mesylate
Pefloxacinium mesylate,甲磺酸培氟沙星 |
Topoisomerase; Antibacterial; Antibiotic | DNA Damage/DNA Repair; Microbiology/Virology |
Pefloxacin Mesylate (Pefloxacinium mesylate) 是一种抗菌化合物,可抑制DNA 旋转酶阻断DNA 复制。 | |||
T20711 |
Hemipyocyanine
1-羟基吩嗪,528-71-2 |
Amylase | Metabolism |
Hemipyocyanine (528-71-2) 是一种 α-淀粉酶抑制剂。 | |||
T12992 |
SPR741 acetate
SPR741 acetate,NAB741 acetate,SPR741 acetate (1179330-52-9 free base) |
Antibacterial | Microbiology/Virology |
SPR741 acetate 是衍生自多粘菌素 B 的阳离子肽,通过增加革兰氏阴性细菌外膜的通透性来抑制严重的革兰氏阴性细菌感从而展现出对革兰氏阴性菌的抗菌活性。SPR741 acetate 常与抗生素联合使用来治疗一些疾病。 | |||
T6492 |
Davercin
环酯红霉素,Erythromycin Cyclocarbonate |
Antibacterial; Antibiotic | Microbiology/Virology |
Davercin (Erythromycin Cyclocarbonate) 是 Erythromycin 的衍生物,对革兰氏阳性菌和一些革兰氏阴性菌有活性。 | |||
T1640 |
Ciprofloxacin
Ciproxan,环丙沙星,Ciprobay,Bay o 9867,Bay-09867 |
Topoisomerase; Antibacterial; Antibiotic | DNA Damage/DNA Repair; Microbiology/Virology |
Ciprofloxacin (Bay-09867) 是一种有高抗菌活性的氟喹诺酮类抗生素。 | |||
T1037 |
Doripenem monohydrate
多尼培南(一水合物),S 4661 monohydrate,Doripenem Hydrate,S-4661 |
Antibacterial; Antibiotic | Microbiology/Virology |
Doripenem monohydrate (S 4661 monohydrate) 是广谱β-内酰胺抗生素,它对革兰氏阳性,阴性和厌氧菌有抗菌作用。 |
Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T2P2937 |
Nonacosane
|
Others; Antibacterial | Microbiology/Virology; Others |
Nonacosane 是从Baphia massaiensis 分离的,是一种由 29 个碳原子组成的直链烷烃,具有植物代谢物和挥发油成分的作用。 | |||
T8126 |
Cefodizime Sodium
|
Others; Antibacterial; Antibiotic | Microbiology/Virology; Others |
Cefodizime sodium 是一种头孢菌素抗生素,具有抗菌活性。它对肾脏没有毒性,具有良好的耐受性和免疫调节活性,可研究呼吸道和泌尿道的严重感染。 | |||
T4S0867 |
Pogostone
DHELWANGIN,广藿香酮 |
Apoptosis; Antibacterial; Autophagy | Apoptosis; Autophagy; Microbiology/Virology |
Pogostone (DHELWANGIN) 是从薄荷中分离出,对革兰氏阴性菌、革兰氏阳性菌、大肠埃希菌等具有强效抗菌、抗真菌活性。它诱导细胞凋亡和自噬。 | |||
T8118 |
Bekanamycin
Kanamycin B,卡那霉素,卡那霉素 B |
Antibacterial; Antibiotic | Microbiology/Virology |
Bekanamycin (Kanamycin B) 是一种提取自 Streptomyces kanamyceticus 的氨基糖苷类抗生素,抑制一系列革兰氏阳性和阴性细菌。 | |||
T0895 |
Oxytetracycline
土霉素,Terramycin |
ribosome; Endogenous Metabolite; Antibacterial; Antibiotic; HSV | Metabolism; Microbiology/Virology |
Oxytetracycline (Terramycin) 是一种四环素类抗生素。它强力抑制革兰氏阴性和革兰氏阳性细菌。它是一种蛋白质合成抑制剂,可阻止 aminoacil-tRNA 与复杂的核糖体 RNA 结合,具有抗 HSV-1的活性。 | |||
T0224 |
Meropenem
美罗培南,SM 7338 |
Others; Antibacterial; Antibiotic | Microbiology/Virology; Others |
Meropenem (SM 7338) 是一种具有广谱抗菌活性的碳青霉烯抗生素,对敏感和耐药的淋病奈瑟氏球菌,流感嗜血杆菌和杜克氏杆菌的 MIC 值分别为 0.02-0.06 mg/mL,0.03-0.12 mg/mL 和 0.015-0.12 mg/mL。 | |||
T19808 |
5-Bromo-5-nitro-1,3-dioxane
Bronidox,5-溴-5-硝基-1,3-二噁烷,5-溴-5-硝基-1,3-二恶烷 |
Others; Antibacterial; Antifungal | Microbiology/Virology; Others |
5-Bromo-5-nitro-1,3-dioxane (Bronidox) 是一种抗菌化合物,可通过必需蛋白硫醇的氧化抑制酶活性并随后抑制微生物的生长。它有抗革兰氏阳性和革兰氏阴性细菌,以及抗真菌活性。 | |||
T8160 |
EGCG Octaacetate
乙酰化表没食子儿茶素没食子酸酯,乙酰化EGCG |
Others; Antibacterial | Microbiology/Virology; Others |
EGCG Octaacetate 是表没食子儿茶素没食子酸酯的前药,对革兰氏阳性菌和革兰氏阴性菌有潜在抗菌可能。它可下调 PI3K/Akt/NFκB 磷酸化和 p65 乙酰化来降低促炎介质水平,减少小鼠结肠炎引起的结肠癌。 | |||
T6624 |
Oxytetracycline Dihydrate
土霉素二水合物,地霉素,Terramycin Dihydrate |
Others; Endogenous Metabolite; Antibacterial; Antibiotic; HSV | Metabolism; Microbiology/Virology; Others |
Oxytetracycline Dihydrate (Terramycin Dihydrate) 是一种四环素类抗生素,可抑制革兰氏阴性和革兰氏阳性细菌。它是一种蛋白质合成抑制剂,可阻止 aminoacil-tRNA 与复杂的核糖体 RNA 结合,还具有抗 HSV-1的活性。 | |||
T0788 |
Spectinomycin dihydrochloride
淋必治,Spectinomycin 2HCl,盐酸奇霉素,Actinospectacin |
ribosome; Antibacterial; Antibiotic | Microbiology/Virology |
Spectinomycin dihydrochloride (Actinospectacin) 是一种能与细菌核糖体的30S 亚基结合,干扰蛋白质合成的抗生素。 | |||
TCS1554 |
trans-Benzylideneacetone
反式苯亚甲基丙酮,Acetocinnamone,亚苄基丙酮 |
Phospholipase | Metabolism |
trans-Benzylideneacetone (Acetocinnamone) 是一种革兰氏阴性致病性线虫细菌嗜线虫(Xenorhabdus nematophila) 的代谢产物,是一种针对磷脂酶 A2 (PLA2) 的酶抑制剂,也是一种免疫抑制剂。 | |||
T21430 |
Oxytetracycline Hydrochloride
Biosolvomycin,盐酸土霉素,Oxytetracycline HCl,Oxytetracycline.HCl,Dalimycin,Oxytetracycline, Sodium Salt,Dalinmycin |
Antiviral; Endogenous Metabolite; Antibacterial; HSV | Immunology/Inflammation; Metabolism; Microbiology/Virology |
Oxytetracycline Hydrochloride (Dalimycin) 是由 Streptomyces rimosus 生产的,一种具有抗菌活性的四环素衍生物。它干扰氨酰-tRNA 与 mRNA-核糖体复合物的结合,从而阻止肽延伸并抑制蛋白质合成。 | |||
TN2011 |
Ombuoside
商陆素-3BETA-芸香糖苷,Ombuin-3beta-rutinoside |
Antibacterial | Microbiology/Virology |
Ombuoside (Ombuin-3beta-rutinoside) 是一种从绞股蓝分离得到的糖苷复合物。它具有抗真菌和抗氧化作用。 | |||
TQ0251 |
(Z)-2-decenoic acid
(Z)-dec-2-enoic acid,(Z)-2-癸烯酸,cis-2-Decenoic acid,cis-dec-2-enoic acid |
Others | Others |
(Z)-2-decenoic acid (cis-dec-2-enoic acid) 是一种由铜绿假单胞菌产生的不饱和脂肪酸。它能够诱导一系列革兰氏阴性细菌(包括铜绿假单胞菌)和革兰氏阳性细菌形成的生物膜发生分散反应。它能够抑制生物膜发育。 | |||
T4984 |
Cefozopran hydrochloride
SCE-2787 hydrochloride |
Antifungal | Microbiology/Virology |
Cefozopran hydrochloride (SCE-2787 hydrochloride) 是一种半合成的非肠道头孢菌素。它是一种广谱抗菌抗生素,能抑制大多数革兰氏阴性和革兰氏阳性菌。 | |||
T8261 |
Ceftazidime Pentahydrate
头孢他啶五水合物,头孢他啶 |
Antibacterial; Antibiotic | Microbiology/Virology |
Ceftazidime pentahydrate 是一种β-内酰胺类抗菌剂,对革兰氏阳性和革兰氏阴性需氧细菌有广谱活性,可静脉内或肌肉给药。它对肠杆菌科特别有效,对大多数 β-内酰胺酶具有抗水解作用。 | |||
T28764 |
SF2312
SF-2312,SF 2312 |
Glucokinase; Antibacterial | Metabolism; Microbiology/Virology |
SF2312 是一种由放线菌微孢子菌产生的天然膦酸盐抗生素,是高效的糖酵解酶烯醇化酶抑制剂。SF2312 具有抗菌活性,可抑制细菌生长,对革兰氏阴性和革兰氏阴性菌均具有抑制作用。SF2312 抑制人重组 ENO1 和 ENO2。 | |||
T8062 |
Cefazedone
Refosporen,头孢西酮 |
Others; Antibacterial; Antibiotic | Microbiology/Virology; Others |
Cefazedone (Refosporen) 是一种具有抗革兰氏阳性和革兰氏阴性菌活性的时间依赖性头孢菌素抗生素。 | |||
T5757 |
Loganetin
|
Antibacterial | Microbiology/Virology |
Loganetin 是无毒的天然产物,来源于Cornus officinalis Sieb. et Zucc.,可用于耐多药革兰氏阴性菌感染的研究。 | |||
T8247 |
(+)-Aromadendrene
|
Anti-infection | Microbiology/Virology |
(+)-Aromadendrene 是一种天然产物,对革兰氏阳性菌和革兰氏阴性菌具有显着的抗菌活性。 | |||
T5037 |
Midecamycin
Antibiotic SF-837,Turimycin P3,Medecamycin A1,Rubimycin,麦迪霉素,Platenomycin B1,Espinomycin A |
Antibacterial; Antibiotic | Microbiology/Virology |
Midecamycin (Medecamycin A1) 是乙酰氧基取代的大环内酯类抗生素,对革兰氏阳性和阴性菌有效。 | |||
T1306 |
Norfloxacin
氟哌酸,MK-0366,诺氟沙星 |
DNA gyrase; Topoisomerase; Endogenous Metabolite; Antibacterial; Antibiotic | DNA Damage/DNA Repair; Metabolism; Microbiology/Virology |
Norfloxacin (MK-0366) 是广谱抗生素,能通过结合DNA 旋转酶抑制革兰氏阳性和阴性菌。 | |||
T1679 |
Thiostrepton
Thiactin,Bryamycin,Alaninamide,硫链丝菌素 |
DNA/RNA Synthesis; Antibacterial; Antibiotic | Cell Cycle/Checkpoint; DNA Damage/DNA Repair; Microbiology/Virology |
Thiostrepton (Alaninamide) 是一种选择性抑制FOXM1的抗生素。FOXM1会与 YAP/TEAD 复合物结合,形成YAP/TEAD/FOXM1 复合物。 | |||
T5S0814 |
Berberine hydrogen sulphate
Berberine Bisulfate,硫酸氢黄连素,Umbellatine Sulfate |
Antibacterial | Microbiology/Virology |
Berberine hydrogen sulphate (Umbellatine Sulfate) 是一种从几种植物中提取的生物碱,对多种微生物具有抗菌活性,包括革兰氏阳性和革兰氏阴性细菌、真菌和原生动物。 | |||
T5274 |
D-(+)-Phenyllactic acid
D-3-苯乳酸,D-3-Phenyllactic acid |
Endogenous Metabolite; Antibacterial | Metabolism; Microbiology/Virology |
D-(+)-Phenyllactic acid (D-3-Phenyllactic acid) 是一种由白地霉分泌得到的抗菌剂,可抑制部分来自人类和食品的革兰氏阳性菌以及来自人类的革兰氏阴性菌。 | |||
T0814L |
Ampicillin
Amcill,D-(-)-α-Aminobenzylpenicillin,Aminobenzylpenicillin,氨苄青霉素,Ampicillin acid |
Antibacterial; Antibiotic | Microbiology/Virology |
Ampicillin (Aminobenzylpenicillin) 属于 β-内酰胺类抗生素,是一种半合成的青霉素。Ampicillin 具有杀菌活性,对各种革兰氏阳性细菌和革兰氏阴性细菌均有抑制活性。 | |||
T4889 |
2,6-Diaminoheptanedioic acid
|
Others; Endogenous Metabolite | Metabolism; Others |
2,6-Diaminoheptanedioic acid 是内源性代谢产物的一种。 | |||
T8302 |
Ceftiofur
|
Antibacterial; Antibiotic | Microbiology/Virology |
Ceftiofur 是一种半合成抗生素,对家畜的各种革兰氏阳性和革兰氏阴性菌、好氧菌和厌氧菌均有抗菌活性。 | |||
T3501 |
Colistimethate Sodium
Colistin-1,3,5,9-tetramethanesulfonic A acid,多粘菌素E甲磺酸钠 |
Others | Others |
Colistin-1,3,5,9-tetramethanesulfonic A acid 用于治疗选择有限的患者因选定的需氧革兰氏阴性病原体引起的严重感染。 | |||
T12830 |
Sapienic acid sodium
|
Antibacterial | Microbiology/Virology |
Sapienic acid sodium,主要存在于皮肤和粘膜中的脂肪酸,对皮肤和口腔内的革兰氏阳性及阴性细菌展现出不同程度的抗菌效果。其对血链球菌、微生物链球菌与核纤梭菌的抗菌活性表现,MBC值分别为31.3 μg/mL、375.0 μg/mL与93.8 μg/mL。 | |||
T0958 |
Penicillin G sodium salt
青霉素钠,Penicillin G Sodium,Benzylpenicillin sodium salt,Benzylpenicillin Sodium |
GABA Receptor; Antibacterial; Antibiotic | Membrane transporter/Ion channel; Microbiology/Virology; Neuroscience |
Penicillin G sodium(Benzylpenicillin sodium) salt 是一种 β-内酰胺类抗生素。 | |||
T1313 |
Nitrofurantoin
Furadantine,呋喃妥因,Macrodantin,Furadonine |
Antibacterial; Antibiotic | Microbiology/Virology |
Nitrofurantoin (Furadantine) 是一种具有口服活性的广谱内酰胺酶抗菌剂。它是一种抗生素,可研究尿路感染。 | |||
T8148 |
Mupirocin calcium hydrate
莫匹罗星钙,Mupirocin calcium |
Others; Antibacterial; Antibiotic | Microbiology/Virology; Others |
Mupirocin calcium hydrate 是从Pseudomonas fluorescens 中分离得到的,一种有口服活性的抗生素。它可逆地抑制异亮氨酸转移RNA,并抑制细菌蛋白和RNA 的合成起到抗菌作用。 | |||
T2989 |
4-Hydroxybenzoic acid
p-hydroxybenzoic acid,para-Hydroxybenzoic acid,PHBA,对羟基苯甲酸,4-hydroxybenzoate |
Endogenous Metabolite; Antibacterial | Metabolism; Microbiology/Virology |
4-Hydroxybenzoic acid (4-hydroxybenzoate) 是苯甲酸的酚衍生物,可抑制革兰氏阳性和革兰氏阴性菌,IC50值为160 μg/mL。 | |||
T1304 |
Chlortetracycline hydrochloride
Isphamycin,Chlortetracycline HCl,7-Chlorotetracycline hydrochloride,盐酸金霉素 |
ribosome; Antibacterial; Antibiotic | Microbiology/Virology |
Chlortetracycline hydrochloride (Isphamycin) 是一种特异性钙离子载体抗生素, 抑制氨酰 tRNA 结合到核糖体。 | |||
T40583 |
3-Oxo-C14-AHL
N-(3-Oxotetradecanoyl)-DL-homoserine lactone |
Others | Others |
3-Oxo-C14-AHL (N-(3-Oxotetradecanoyl)-DL-homoserine lactone) 是由革兰氏阴性菌产生的群体感应 (QS) 信号分子,可用来提高能农作物的产量。 | |||
T20643 |
Cefoxitin
Rephoxitin,Cefoxitinum |
Cell wall; Antibacterial; Antibiotic | Immunology/Inflammation; Microbiology/Virology |
Cefoxitin (Rephoxitin) 是一种广谱的、可口服的第二代头孢霉素类抗生素。Cefoxitin 干扰细菌细胞壁的合成。其活性谱包括革兰氏阴性和革兰氏阳性菌,通常用于腹腔感染、盆腔感染和某些类型的妇科感染等腹部,对厌氧菌具有高效性。 | |||
T8262 |
Fosfomycin sodium
Fosfomycin Disodium,磷霉素钠 |
Antibacterial; Antibiotic | Microbiology/Virology |
Fosfomycin sodium 是一种能透过血脑屏障的广谱抗生素,不可逆地抑制细胞壁合成的早期阶段。它对多种细菌具有杀菌活性,包括耐多药、广泛耐药和耐全药的细菌。 | |||
T1100 |
Polymyxin B Sulfate
Aerosporin,硫酸多粘菌素 B,PMB,Polymyxin B sulphate,硫酸多粘菌素B,Polymyxin B sulfate (1404-26-8 free base),Poly-RX |
Antibacterial; Antibiotic | Microbiology/Virology |
Polymyxin B Sulfate (Poly-RX) 是一个阳离子型表面活性剂抗生素剂,能够提高细胞膜的渗透性。 | |||
T1104 |
Paromomycin Sulfate
Aminosidine sulfate,Paromomycin sulfate salt,硫酸巴龙霉素,巴龙霉素硫酸盐 |
Antibacterial; Antibiotic; Parasite | Microbiology/Virology |
Paromomycin Sulfate (Aminosidine sulfate) 是一种广谱氨基糖苷类抗生素 ,是具有杀螨杀菌作用的新霉素衍生物。它通过与细菌 30S 核糖体 A 位点的 RNA 寡核苷酸特异性结合,使 mRNA 的翻译提前终止,并抑制蛋白质合成。它可研究细菌和寄生虫感染。 | |||
T11855 |
Lipopolysaccharides
脂多糖,LPS |
Others | Others |
Lipopolysaccharides (LPS) 是革兰氏阴性细菌细胞壁的一种特有成分,由脂质A、寡糖核心和 O -特异性多糖 (O-antigen) 3个区域组成。Lipopolysaccharides 有利于维持细胞外膜的完整性,保护细菌免受胆汁盐和脂类抗生素的破坏。Lipopolysaccharides 是一种高免疫原性抗原,可以增强免疫反应,可以用于炎症模型构建。 | |||
T41078 |
Lipopolysaccharides, Escherichiacoli
Lipopolysaccharide, E. coli O111:B4 |
Others | Others |
Lipopolysaccharides, Escherichiacoli (E. coli O111:B4) 是革兰氏阴性细菌细胞壁的一种特有成分,由脂质A、寡糖核心和 O -特异性多糖 (O-antigen) 3个区域组成。Lipopolysaccharides, Escherichiacoli 有利于维持细胞外膜的完整性,保护细菌免受胆汁盐和脂类抗生素的破坏。Lipopolysaccharides, Escherichiacoli 是一种高免疫原性抗原,可以增强免疫反应,可以用于炎症模型构建。 | |||
TN4518 |
Meridinol
|
Antifection | Microbiology/Virology |
Meridinol has wide antimicrobial activity, includes against gram-positive and gram-negative bacteria and fungi. | |||
T26805 |
Bicyclomycin
Bicozamycin |
Others | Others |
Bicyclomycin is a broad spectrum antibiotic active against Gram-negative bacteria and the Gram-positive bacterium, Micrococcus luteusn. | |||
TN6002 |
Crenatine
1-Ethyl-4-methoxy-β-carboline |
||
Crenatine possesses antibacterial activity, it is more effective against Gram-positive than Gram-negative bacteria. | |||
T1255L |
Tobramycin Sulfate
Dartobcin,Nebcine,Tobraneg,Tobrasix |
Others | Others |
Tobramycin Sulfate is a broad-spectrum antibiotic. It is effective against gram-negative bacteria. It especially potent against the Pseudomonas species. | |||
T25971 |
Polymyxin B2
Polymyxin-B2,PolymyxinB2 |
Others | Others |
Polymyxin B2 is an antibiotic primarily utilized for resistant Gram-negative infections. It is derived from the bacterium Bacillus polymyxa. | |||
T16673 |
Pseudouridimycin
PUM |
Others | Others |
Pseudouridimycin is a C-nucleoside analogue. Pseudouridimycin is an antibiotic and is a selective bacterial RNA polymerase (RNAP) inhibitor. It is effective against both Gram-negative and Gram-positive bacteria. | |||
T4131 | Arjunic acid | COX; Antifection | Immunology/Inflammation; Microbiology/Virology; Neuroscience |
Arjunic acid is a strong antioxidant and a free radical scavenger. Arjunic acid shows activity against Gram-positive and Gram-negative bacteria with MIC values ranging between 1.9 and 15.6 microg/mL. | |||
TN1301 |
6,8-Diprenylgenistein
6,8-二异戊烯基金雀异黄素,鲁冰花 |
Antifection | Microbiology/Virology |
6,8-Diprenylgenistein has antimicrobial activity, it has anti-bacteria activity against Gram-negative and Gram-positive bacteria. | |||
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Cat. No. | Product Name | Species | Expression System |
---|---|---|---|
TMPY-03118 |
ORM2 Protein, Human, Recombinant (His)
AGP-B',ORM2,orosomucoid 2,AGP-B,AGP2 |
Human | HEK293 Cells |
ORM2 belongs to the calycin superfamily, lipocalin family. Lipocalins share limited regions of sequence homology and a common tertiary structure architecture. They transport small hydrophobic molecules such as steroids, bilins, retinoids, and lipids. Lipocalins can be found in gram-negative bacteria, vertebrate cells, and invertebrate cells, and plants. They are associated with many biological processes. ORM2 functions as a transport protein in the bloodstream. It is expressed by the liver and s... | |||
TMPY-02204 |
LBP Protein, Human, Recombinant (His)
BPIFD2,lipopolysaccharide binding protein |
Human | HEK293 Cells |
Lipopolysaccharide binding protein ( LBP ) is a glycoprotein that is synthesized principally by hepatocytes. LBP is a trace plasma protein that binds to the lipid A moiety of bacterial lipopolysaccharides ( LPSs ). LBP binds directly to the outer membrane of Gram-negative bacteria and purified aggregates of extracted endotoxin and catalyzes the delivery of endotoxin to the membrane ( mCD14, GPI-Linked ) and soluble ( sCD14 ) forms of CD14, thereby markedly increasing host cell sensitivity to end... | |||
TMPY-02904 |
TLR4 Protein, Human, Recombinant (His)
TLR-4,TOLL,toll-like receptor 4,ARMD10,TLR4,CD284 |
Human | Baculovirus Insect Cells |
TLR4, also known as TLR-4, is a member of the Toll-like receptor (TLR) family, which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns (PAMPs) that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. TLR4 is most abundantly expressed... | |||
TMPH-02773 |
Lysozyme C-2 Protein, Mouse, Recombinant (His & Myc)
Lysozyme C-2,1,4-beta-N-acetylmuramidase C,Lysozyme C type M... |
Mouse | E. coli |
Lysozymes have primarily a bacteriolytic function; those in tissues and body fluids are associated with the monocyte-macrophage system and enhance the activity of immunoagents. Lyz2 is active against a range of Gram-positive and Gram-negative bacteria. More effective than Lyz1 in killing Gram-negative bacteria. Lyz1 and Lyz2 are equally effective in killing Gram-positive bacteria. Lysozyme C-2 Protein, Mouse, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-M... | |||
TMPY-02908 |
BPI Protein, Human, Recombinant (His)
BPIFD1,bactericidal/permeability-increasing protein,rBPI |
Human | HEK293 Cells |
Bactericidal/permeability-increasing protein is a member of the BPI/LBP/Plunc superfamily and BPI/LBP family. It is a cationic protein which can be detected in the azurophilic granule and on the surface of polymorphonuclear leukocytes. Bactericidal/permeability-increasing protein also is a lipopolysaccharide binding protein. It is associated with human neutrophil granules and has bactericidal activity on gram-negative organisms. Bactericidal/permeability-increasing protein contains two domains t... | |||
TMPH-00230 |
Cathelicidin-6 Protein, Bovine, Recombinant (His & SUMO)
CATHL6,Antibacterial peptide BMAP-27,Myeloid antibacterial p... |
Bovine | E. coli |
Exerts a potent antimicrobial activity against Gram-negative and Gram-positive bacteria, including methicillin-resistant Staphylococcus aureus, and fungi. Cathelicidin-6 Protein, Bovine, Recombinant (His & SUMO) is expressed in E. coli expression system with N-6xHis-SUMO tag. The predicted molecular weight is 16.2 kDa and the accession number is P54228. | |||
TMPH-01772 |
DEFA1 Protein, Human, Recombinant (GST)
MRS,HP1,HP-1,DEFA1,DEF1,Defensin, alpha 1,Neutrophil defensi... |
Human | E. coli |
Defensin 1 and defensin 2 have antibacterial, fungicide and antiviral activities. Has antimicrobial activity against Gram-negative and Gram-positive bacteria. Defensins are thought to kill microbes by permeabilizing their plasma membrane. DEFA1 Protein, Human, Recombinant (GST) is expressed in E. coli expression system with N-GST tag. The predicted molecular weight is 37.2 kDa and the accession number is P59665. | |||
TMPH-02544 |
DEFB4 Protein, Mouse, Recombinant (His & SUMO)
Bdef4,BD-4,Beta-defensin 4,Defensin, beta 4,mBD-4,Defb4 |
Mouse | E. coli |
Exhibits antimicrobial activity against Gram-negative bacteria and Gram-positive bacteria. May act as a ligand for C-C chemokine receptor CCR6. Can bind to mouse (but not human) CCR6 and induce chemotactic activity of CCR6-expressing cells. DEFB4 Protein, Mouse, Recombinant (His & SUMO) is expressed in E. coli expression system with N-6xHis-SUMO tag. The predicted molecular weight is 20.6 kDa and the accession number is P82019. | |||
TMPH-03145 |
Thanatin Protein, Podisus maculiventris, Recombinant (His & KSI)
Thanatin |
Podisus maculiventris | E. coli |
Insect defense peptide with a broad spectrum of activity against Gram-positive and Gram-negative bacteria and fungi. No activity against S.aureus. Stops respiration in bacteria but does not permeabilize their inner membranes. Thanatin Protein, Podisus maculiventris, Recombinant (His & KSI) is expressed in E. coli expression system with N-6xHis-KSI tag. The predicted molecular weight is 17.8 kDa and the accession number is P55788. | |||
TMPH-03100 |
PMAP-23 Protein, Pig, Recombinant (His & SUMO)
PMAP23,Antibacterial peptide PMAP-23,Myeloid antibacterial p... |
Sus scrofa (Pig) | E. coli |
Exerts antimicrobial activity against both Gram-positive and negative bacteria at concentrations of 2-16 micro molar. Its activity appears to be mediated by its ability to damage bacterial membranes. PMAP-23 Protein, Pig, Recombinant (His & SUMO) is expressed in E. coli expression system with N-6xHis-SUMO tag. The predicted molecular weight is 19.0 kDa and the accession number is P49930. | |||
TMPH-01607 |
LCE3A Protein, Human, Recombinant (His)
Late envelope protein 13,LCE3A,Late cornified envelope prote... |
Human | E. coli |
A structural component of the cornified envelope of the stratum corneum involved in innate cutaneous host defense (Probable). Possesses defensin-like antimicrobial activity against a broad spectrum of Gram-positive and Gram-negative bacteria, both aerobic and anaerobic species. Upon inflammation, may regulate skin barrier repair by shaping cutaneous microbiota composition and immune response to bacterial antigens. LCE3A Protein, Human, Recombinant (His) is expressed in E. coli expression system ... | |||
TMPJ-00574 |
RNASE3 Protein, Human, Recombinant (His)
RNase 3,RNS3,ECP,Eosinophil Cationic Protein,RNASE3,Ribonucl... |
Human | HEK293 Cells |
Ribonuclease 3 (RNASE3) is a basic protein that is localized to the eosinophil primary matrix and belongs to the pancreatic ribonuclease family. RNASE3 is released during degranulation of eosinophils. RNASE3 possesses a wide variety of biological activities. RNASE3 interacts with bacterial lipopolysaccharide (LPS) and lipoteichoic acid (LTA). RNASE3 exhibits antibacterial activity, including cytoplasmic membrane depolarization of preferentially Gram-negative, but also Gram-positive strains. It p... | |||
TMPY-02163 |
PGLYRP1 Protein, Mouse, Recombinant (His)
Tnfsf3l,peptidoglycan recognition protein 1,PGRP,Tasg7,Tag7,... |
Mouse | HEK293 Cells |
Peptidoglycan recognition protein 1, also known as Peptidoglycan recognition protein short, PGRP-S, PGLYRP1, PGLYRP, PGRP and TNFSF3L, is a secreted protein that belongs to the N-acetylmuramoyl-L-alanine amidase 2 family. PGLYRP1 / PGLYRP is highly expressed in bone marrow. It is weakly expressed in kidney, liver, small intestine, spleen, thymus, peripheral leukocyte, lung, fetal spleen and neutrophils. PGLYRP1 / PGLYRP is a pattern receptor that binds to murein peptidoglycans (PGN) of Gram-posi... | |||
TMPH-00064 |
MRJP1 Protein, Apis mellifera, Recombinant (His)
Royalactin,Major royal jelly protein 1,Apalbumin 1,MRJP1,56-... |
Apis mellifera | P. pastoris (Yeast) |
Induces the differentiation of honeybee larvae into queens through an Egfr-mediated signaling pathway. Promotes body size increase by activating p70 S6 kinase, stimulates ovary development by augmenting the titer of vitellogenin (Vg) and juvenile hormone, and reduces developmental time by increasing the activity of mitogen-activated protein kinase and inducing the 20-hydroxyecdysone protein (20E). Most abundant protein found in the royal jelly which is the food of the queen honey bee larva. The ... | |||
TMPK-01242 |
MD2/LY96 Protein, Human, Recombinant (His)
MD-2,Ly-96,ESOP-1,Lymphocyte antigen 96,LY96,ESOP1 |
Human | E. coli |
MD2, a 160-residue accessory glycoprotein, is responsible for the recognition and binding of Gram-negative bacterial membrane component, lipopolysaccharide (LPS).Internalization of pathogen inside the mononuclear phagocytes has also been attributed to MD2 which leads to the clearance of pathogens from the host. MD2/LY96 Protein, Human, Recombinant (His) is expressed in E. coli expression system with C-His tag. The predicted molecular weight is 18.07 kDa and the accession number is Q9Y6Y9-1. | |||
TMPK-00632 |
MD2/LY96 Protein, Cynomolgus, Recombinant (His)
ESOP-1,LY96,Lymphocyte antigen 96,ESOP1,MD-2 |
Cynomolgus | E. coli |
MD2, a 160-residue accessory glycoprotein, is responsible for the recognition and binding of Gram-negative bacterial membrane component, lipopolysaccharide (LPS).Internalization of pathogen inside the mononuclear phagocytes has also been attributed to MD2 which leads to the clearance of pathogens from the host. MD2/LY96 Protein, Cynomolgus, Recombinant (His) is expressed in E. coli expression system with C-His tag. The predicted molecular weight is 17.97 kDa and the accession number is B3Y6B0. | |||
TMPY-03999 |
MD2/LY96 Protein, Mouse, Recombinant (hFc)
lymphocyte antigen 96,ESOP-1,MD2,MD-2 |
Mouse | HEK293 Cells |
LY96 (Lymphocyte Antigen 96, also known as ESOP-1) is a Protein Coding gene. 2 alternatively spliced human isoforms have been reported. This gene encodes a protein that associates with toll-like receptor 4 on the cell surface and confers responsiveness to lipopolysaccharide (LPS), thus providing a link between the receptor and LPS signaling. LY-96 also cooperates with TLR2 in the response to cell wall components from Gram-positive and Gram-negative bacteria. It enhances the TLR4-dependent activa... | |||
TMPH-01540 |
Intelectin-1/ITLN1 Protein, Human, Recombinant (His & Myc)
Galactofuranose-binding lectin,Endothelial lectin HL-1,Intel... |
Human | E. coli |
Lectin that specifically recognizes microbial carbohydrate chains in a calcium-dependent manner. Binds to microbial glycans that contain a terminal acyclic 1,2-diol moiety, including beta-linked D-galactofuranose (beta-Galf), D-phosphoglycerol-modified glycans, D-glycero-D-talo-oct-2-ulosonic acid (KO) and 3-deoxy-D-manno-oct-2-ulosonic acid (KDO). Binds to glycans from Gram-positive and Gram-negative bacteria, including K.pneumoniae, S.pneumoniae, Y.pestis, P.mirabilis and P.vulgaris. Does not ... | |||
TMPY-02835 |
DEFB103A Protein, Human, Recombinant (His)
DEFB3,HBP3,defensin, beta 103A,hBD-3,DEFB103,DEFB-3,HBD3,HBP... |
Human | E. coli |
Beta-defensin 3 is a member of the defensin family. Defensin family is comprised by microbicidal and cytotoxic peptides made by neutrophils. Members of the beta-defensin 3 family are highly similar in protein sequence. Beta-defensin 3 shows antimicrobial activity against Gram-positive bacteria S.aureus and S.pyogenes, Gram-negative bacteria P.aeruginosa and E.coli and the yeast C.albicans. Beta-defensin 3 is abundantly expressed in skin and tonsils, and to a lesser extent in trachea, uterus, kid... | |||
TMPY-03728 |
CCL28 Protein, Human, Recombinant (His)
MEC,SCYA28,chemokine (C-C motif) ligand 28,CCK1 |
Human | E. coli |
CCL28 chemokine is expressed by epithelial cells of various mucosal tissues. This chemokine binds to CCR3 and CCR10 receptors and plays an essential role in the IgA antibody secreting cells (IgA-ASC) homing to mucosal surfaces and lactating mammary gland as well. Besides, CCL28 has been shown to exert a potent antimicrobial activity against both Gram-negative and Gram-positive bacteria and fungi. The potent antimicrobial function of CCL28 combined with its wide distribution in mucosal tissues an... | |||
TMPY-02375 |
acnB Protein, E. coli, Recombinant
yacI,yacJ |
E. coli | E. coli |
Escherichia coli contains two major aconitases (Acns), AcnA and AcnB. They are distantly related monomeric Fe-S proteins that contain different arrangements of four structural domains. acnA is specifically subject to SoxRS-mediated activation, whereas acnB encodes the major aconitase that is synthesized earlier in the growth cycle than AcnA. It is concluded that AcnB is the major citric acid cycle enzyme. Aconitate hydratase 2 (acnB) catalyzes the isomerization of citrate to isocitrate via cis-a... | |||
TMPH-02671 |
Gasdermin-D Protein, Mouse, Recombinant (His & Myc)
Gasdermin-D,Gasdermin domain-containing protein 1,Gsdmd |
Mouse | E. coli |
Precursor of a pore-forming protein that plays a key role in host defense against pathogen infection and danger signals. This form constitutes the precursor of the pore-forming protein: upon cleavage, the released N-terminal moiety (Gasdermin-D, N-terminal) binds to membranes and forms pores, triggering pyroptosis.; Promotes pyroptosis in response to microbial infection and danger signals. Produced by the cleavage of gasdermin-D by inflammatory caspases CASP1 or CASP4/CASP11 in response to canon... |
Cat. No. | Product Name | Target | Signaling Pathways |
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TMID-0079 |
Norfloxacin-d8
|
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Norfloxacin-d8 是 Norfloxacin 的氘代化合物。Norfloxacin 的 CAS 号为 70458-96-7。Norfloxacin是广谱抗生素,能通过结合DNA旋转酶抑制革兰氏阳性和阴性菌。 | |||
TMID-0271 |
Miloxacin-d3
|
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Miloxacin-d3 是 Miloxacin 的氘代化合物。Miloxacin 的 CAS 号为 37065-29-5。 | |||
TMIH-0154 |
Ciprofloxacin-d8
|
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Ciprofloxacin-d8 是 Ciprofloxacin 的氘代化合物。Ciprofloxacin 的 CAS 号为 85721-33-1。Ciprofloxacin是一种有高抗菌活性的氟喹诺酮类抗生素。 | |||
T37250 |
Cefazolin-13C2,15N
Cefazolin-13C2,15N |
||
Cefazolin-13C2,15N is intended for use as an internal standard for the quantification of cefazolin by GC- or LC-MS. Cefazolin is a broad-spectrum cephalosporin antibiotic that is active in vitro against various Gram-positive and Gram-negative bacteria (MICs = 0.2-12.5 μg/ml). It also inhibits the growth of clinical isolates of S. aureus, E. coli, P. mirabilis, and K. pneumoniae (MICs = 0.1-25 μg/ml). In vivo, cefazolin protects against S. aureus, E. coli, and P. mirabilis infection in mice (ED50... | |||
TMIJ-0059 |
Moxifloxacin-d4
|
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Moxifloxacin-d4 是 Moxifloxacin 的氘代化合物。Moxifloxacin 的 CAS 号为 151096-09-2。Moxifloxacin 是一种8-甲氧基喹诺酮类口服有效抗菌药物,用于急性细菌性鼻窦炎,慢性支气管炎的急性细菌性加重和感染性肺炎的研究。 | |||
TMID-0281 |
Moxifloxacin-13C-d3
|
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Moxifloxacin-13C-d3 是 Moxifloxacin 的 13C 和氘代化合物。Moxifloxacin 的 CAS 号为 151096-09-2。Moxifloxacin 是一种8-甲氧基喹诺酮类口服有效抗菌药物,用于急性细菌性鼻窦炎,慢性支气管炎的急性细菌性加重和感染性肺炎的研究。 | |||
TMIJ-0327 |
Cefpodoxime-d3 Acid
|
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Cefpodoxime-d3 Acid 是 Cefpodoxime Acid 的氘代化合物。Cefpodoxime Acid 的 CAS 号为 80210-62-4。Cefpodoxime (free acid) 是一种口服的第三代头孢菌素抗生素。除铜绿假单胞菌、肠球菌和脆弱拟杆菌外,它对大多数革兰氏阳性和革兰氏阴性微生物均有效。 | |||
TMID-0290 |
Cefpodoxime proxetil-d3
|
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Cefpodoxime proxetil-d3 是 Cefpodoxime proxetil 的氘代化合物。Cefpodoxime proxetil 的 CAS 号为 87239-81-4。Cefpodoxime Proxetil 是一种口服的广谱型抗生素。它与青霉素结合蛋白结合,抑制肽聚糖的合成,干扰细菌细胞壁的生物合成。 | |||
TMID-0072 |
Imipenem-d4
|
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Imipenem-d4 是 Imipenem 的氘代化合物。Imipenem 的 CAS 号为 64221-86-9。Imipenem (MK0787) 是一种噻吩霉素衍生物,属于抗生素类,具有抗菌活性,对革兰氏阳性和革兰氏阴性菌具有部分的抑制作用。Imipenem 可用于研究碳青霉烯类非易感性感染和铜绿假单胞菌生物膜感染。 |