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Search Results for " gp41 "

Targets Recommended: Others

抑制剂 & 化合物

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重组蛋白

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Cat. No.	Product Name	Target	Signaling Pathways
T26392	5M038	Others	Others
	5M038, a novel inhibitor of HIV envelope-mediated fusion, strongly inhibits gp41-mediated membrane fusion.
T81716	N36 peptide
	N36 peptide 是一种具有生物活性的肽类化合物，属于 (HIV-1 gp41融合肽)。
T82482	ELDKWA
	ELDKWA为gp41胞外域中极为保守的氨基酸序列，它是针对HIV-1的中和单克隆抗体2F5 (mAb 2F5)的靶向表位。
T28133	NB-64	Others	Others
	NB-64 is a HIV-1 entry inhibitor. NB-64 interferes the gp41 six-helix bundle formation and blocks virus fusion.
T76513	2F5 epitope
	2F5 epitope 是肽 gp41 (659-671) 片段，包含能够中和广谱初级HIV-1分离株的三种已知抗体之一的完整表位，并且是连续表位。2F5 epitope 被广泛中和抗体 2F5 识别。
TP1743	MPG, HIV related
	MPG, a 27-amino acid peptide compound, is derived from the fusion peptide domain of HIV-1 gp41 and the nuclear localisation sequence of SV40 large T antigen. As a potent delivery agent, MPG enables efficient and widespread transport of nucleic acids and oligonucleotides into cultured cells.
T80264	C34 peptide
	C34 peptide是一种生物活性肽，亦名HR2，为HIV gp41螺旋区的C端七肽重复2（HR2），亦称C螺旋或C肽。该肽是HIV-1细胞膜融合过程的有效抑制剂，从而阻断病毒入侵细胞。

化合物

Cat. No.	Product Name	Target	Signaling Pathways
T2S0731	Trilobatin 三叶苷,三叶甙,P-Phlorizin	Amylase	Metabolism
	Trilobatin (P-Phlorizin) 是源自Lithocarpus polystachyusRehd 的甜味剂，是一种HIV-1抑制剂，靶向 Gp41 包膜蛋白，具有神经保护作用。它还是SGLT1/2抑制剂，可选择性诱导人肝母细胞瘤细胞增殖。
T5429	Theaflavin 3,3'-digallate 茶黄素-3,3'-双没食子酸,8-Gingerol,TFDG	Virus Protease; Antioxidant; HIV Protease; HSV	Microbiology/Virology; oxidation-reduction; Proteases/Proteasome
	Theaflavin 3,3'-digallate (8-Gingerol) 是一种寨卡病毒蛋白酶抑制剂，IC50为 2.3 μM。它直接与 ZIKVpro 结合并抑制 ZIKV 复制，可抑制 gp41 和 NS2B-3 蛋白酶的活性，并具有抗 HSV 和 HIV-1病毒活性。它是红茶中的主要多酚，有抗肿瘤作用。
TN4605	Myriceric acid B	HIV Protease	Microbiology/Virology; Proteases/Proteasome
	Myriceric acid B is a potent HIV-1 entry inhibitor targeting gp41 and can serve as a lead compound for developing novel anti-HIV-1 drug. Myriceric acid B scavenges DPPH free radicals with IC50 value of 21.8 uM, it inhibits aromatase activity with IC50 val

天然产物

Trilobatin

Cat.No: T2S0731

Synonym: 三叶苷,三叶甙,P-Phlorizin

Target: Amylase

Theaflavin 3,3'-digallate

Cat.No: T5429

Synonym: 茶黄素-3,3'-双没食子酸,8-Gingerol,TFDG

Target: Virus Protease, Antioxidant, HIV Protease, HSV

Myriceric acid B

Cat.No: TN4605

Synonym:

Target: HIV Protease

Species：

Expression System：

Tag：

Cat. No.	Product Name	Species	Expression System
TMPJ-01313	HIV-1 gp120 Protein (His) Envelope glycoprotein gp120,Surface protein gp<...	HIV	HEK293 Cells
	Envelope glycoprotein gp160 is single-pass type I membrane protein. The mature envelope protein (Env) consists of a homotrimer of non-covalently associated gp120-gp41 heterodimers. It is cleaved into the following 2 chains: glycoprotein 120 and transmembrane protein gp41. The resulting complex protrudes from the virus surface as a spike. The 17 amino acids long immunosuppressive region is present in many retroviral envelope proteins. Synthetic peptides derived from this relatively conserved sequ...

重组蛋白

HIV-1 gp120 Protein (His)

Cat.No: TMPJ-01313

Species: HIV

Expression System: HEK293 Cells

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