|
TMPY-04180
|
PfLDH Protein, P. falciparum, Recombinant (His)
PfLDH,L-lactate dehydrogenase
|
P. falciparum
|
E. coli
|
|
Plasmodium falciparum lactate dehydrogenase (PfLDH) is a key enzyme for energy generation of malarial parasites and is considered to be a potential antimalarial target. The ability of PfLDH- or PfIDEh-based immuno-PCR assays to detect <1 parasite/microL suggests that improvements of bound antibody sensor technology may greatly increase the sensitivity of malaria rapid diagnostic tests. The PfLDH test could be used to detect failures and, therefore, to assess anti-malarial efficacy. |
|
TMPH-00683
|
TMAO reductase 1 Protein, E. coli O157:H7, Recombinant (His & Myc)
Trimethylamine-N-oxide reductase 1,torA
|
E. coli
|
E. coli
|
|
Reduces trimethylamine-N-oxide (TMAO) into trimethylamine; an anaerobic reaction coupled to energy-yielding reactions. |
|
TMPH-00508
|
Pro-resilin Protein, Drosophila melanogaster, Recombinant (His & Myc)
Pro-resilin,resilin
|
Fruit fly
|
E. coli
|
|
Plays a central role in insect flight by providing low stiffness, high strain and efficient energy storage. |
|
TMPJ-00007
|
NPY Protein, Human, Recombinant (His)
Pro-Neuropeptide Y,Neuropeptide Y,NPY,C-Flanking Peptide of ...
|
Human
|
HEK293 Cells
|
|
Pro-Neuropeptide Y (NPY) is a member of the NPY family. NPY is a secreted protein and is one of the most abundant peptides in the nervous system. It also can be found in some chromaffin cells of the adrenal medulla. NPY can be cleaved into Neuropeptide Y and C-flanking peptide of NPY chain, which regulates energy usage, and it is involved in learning, memory processing, and epilepsy. NPY is implicated in the control of feeding and in secretion of gonadotrophin-release hormone. In addition, NPY i... |
|
TMPH-00787
|
BtuD Protein, Halobacterium salinarum, Recombinant
Vitamin B12-transporting ATPase,Cobalamin import ATP-binding...
|
Halobacterium salinarum
|
E. coli
|
|
Required for corrinoid utilization. Probably part of the ABC transporter complex BtuCDF involved in cobalamin (vitamin B12) import. Probably responsible for energy coupling to the transport system. |
|
TMPH-00786
|
BtuD Protein, Halobacterium salinarum, Recombinant (His)
Vitamin B12-transporting ATPase,btuD,Cobalamin import ATP-bi...
|
Halobacterium salinarum
|
E. coli
|
|
Required for corrinoid utilization. Probably part of the ABC transporter complex BtuCDF involved in cobalamin (vitamin B12) import. Probably responsible for energy coupling to the transport system. |
|
TMPK-00050
|
Leptin Protein, Mouse, Recombinant (hFc)
LEP,Obesity factor,Leptin,LEPD,Obese protein,OBS,OB
|
Mouse
|
HEK293 Cells
|
|
Leptin has key roles in the regulation of energy balance, body weight, metabolism, and endocrine function. Leptin levels are undetectable or very low in patients with lipodystrophy, hypothalamic amenorrhea, and congenital leptin deficiency (CLD) due to mutations in the leptin gene. |
|
TMPH-03139
|
MDR1 Protein, Plasmodium falciparum, Recombinant (His & SUMO)
Chloroquine resistance protein,MDR1,Multidrug resistance pro...
|
Plasmodium falciparum
|
E. coli
|
|
Energy-dependent efflux pump responsible for decreased drug accumulation in multidrug-resistant cells. MDR1 Protein, Plasmodium falciparum, Recombinant (His & SUMO) is expressed in E. coli expression system with N-6xHis-SUMO tag. The predicted molecular weight is 54.2 kDa and the accession number is P13568. |
|
TMPH-02122
|
SLC2A1 Protein, Human, Recombinant (His & Myc)
Glucose transporter type 1, erythrocyte/brain,HepG2 glucose ...
|
Human
|
E. coli
|
|
Facilitative glucose transporter, which is responsible for constitutive or basal glucose uptake. Has a very broad substrate specificity; can transport a wide range of aldoses including both pentoses and hexoses. Most important energy carrier of the brain: present at the blood-brain barrier and assures the energy-independent, facilitative transport of glucose into the brain. In association with BSG and NXNL1, promotes retinal cone survival by increasing glucose uptake into photoreceptors. SLC2A1 ... |
|
TMPH-00596
|
Colicin-E1 Protein, E. coli, Recombinant (Cell-Free, His & Myc)
Colicin-E1,cea
|
E. coli
|
E. coli
|
|
This colicin is a channel-forming colicin. This class of transmembrane toxins depolarize the cytoplasmic membrane, leading to dissipation of cellular energy.; Colicins are polypeptide toxins produced by and active against E.coli and closely related bacteria. |
|
TMPH-00597
|
Colicin-E1 Protein, E. coli, Recombinant (His & Myc)
cea,Colicin-E1
|
E. coli
|
E. coli
|
|
This colicin is a channel-forming colicin. This class of transmembrane toxins depolarize the cytoplasmic membrane, leading to dissipation of cellular energy.; Colicins are polypeptide toxins produced by and active against E.coli and closely related bacteria. |
|
TMPY-05066
|
IVD Protein, Mouse, Recombinant (His)
6720455E18Rik,AI463340,isovaleryl-CoA dehydrogenase,1300016K...
|
Mouse
|
Baculovirus Insect Cells
|
|
IVD (Isovaleryl-CoA Dehydrogenase) is a Protein Coding gene. IVD is a mitochondrial matrix enzyme that catalyzes the third step in leucine catabolism. IVD plays an essential role in processing proteins obtained from the diet. The body breaks down proteins from food into smaller parts called amino acids. Amino acids can be further processed to provide energy for growth and development. Isovaleryl-CoA dehydrogenase helps process a particular amino acid called leucine. Specifically, isovaleryl-CoA ... |
|
TMPH-03373
|
SLC2A1 Protein, Rat, Recombinant (His & Myc)
Glucose transporter type 1, erythrocyte/brain,Solute carrier...
|
Rat
|
E. coli
|
|
Facilitative glucose transporter, which is responsible for constitutive or basal glucose uptake. Has a very broad substrate specificity; can transport a wide range of aldoses including both pentoses and hexoses. Most important energy carrier of the brain: present at the blood-brain barrier and assures the energy-independent, facilitative transport of glucose into the brain. In association with BSG and NXNL1, promotes retinal cone survival by increasing glucose uptake into photoreceptors. SLC2A1 ... |
|
TMPY-04761
|
Creatine kinase B Protein, Human, Recombinant (His)
HEL-S-29,CKBB,HEL-211,creatine kinase, brain,BCK,B-CK
|
Human
|
Baculovirus Insect Cells
|
|
CKB(Creatine kinase B type) contains 1 phosphagen kinase C-terminal domain and 1 phosphagen kinase N-terminal domain. It belongs to the ATP:guanido phosphotransferase family. CKB consists of a homodimer of two identical brain-type CK-B subunits. CKB is a cytoplasmic enzyme involved in cellular energy homeostasis, with certain fractions of the enzyme being bound to cell membranes, ATPases, and a variety of ATP-requiring enzymes in the cell. There, CKB forms tightly coupled microcompartments ... |
|
TMPY-01869
|
SIRT1 Protein, Human, Recombinant (His)
SIR2L1,sirtuin 1
|
Human
|
E. coli
|
|
SIRT1 belongs to the sirtuin family. Members of the sirtuin family are characterized by a sirtuin core domain and grouped into four classes. SIRT1 is included in class I of the sirtuin family. It is a NAD-dependent protein deacetylase, which regulates processes such as apoptosis and muscle differentiation by deacetylating key proteins. It deacetylates 'Lys-382' of p53/TP53 and impairs its ability to induce proapoptotic program and modulate cell senescence. SIRT1 also deacetylates TAF1B and there... |
|
TMPH-03503
|
Adenylate kinase Protein, Shigella flexneri, Recombinant (His & Myc & SUMO)
ATP-AMP transphosphorylase,AK,Adenylate monophosphate kinase...
|
Shigella flexneri
|
E. coli
|
|
Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism. Adenylate kinase Protein, Shigella flexneri, Recombinant (His & Myc & SUMO) is expressed in E. coli expression system with N-10xHis-SUMO and C-Myc tag. The predicted molecular weight is 43.6 kDa and the accession number is Q83M40. |
|
TMPH-01676
|
Meteorin-like/METRNL Protein, Human, Recombinant (His & SUMO)
METRNL,Meteorin-like protein,Subfatin
|
Human
|
E. coli
|
|
Hormone induced following exercise or cold exposure that promotes energy expenditure. Induced either in the skeletal muscle after exercise or in adipose tissue following cold exposure and is present in the circulation. Able to stimulate energy expenditure associated with the browning of the white fat depots and improves glucose tolerance. Does not promote an increase in a thermogenic gene program via direct action on adipocytes, but acts by stimulating several immune cell subtypes to enter the a... |
|
TMPH-00425
|
DNA ligase Protein, Colwellia psychrerythraea, Recombinant (His)
ligA,DNA ligase,Polydeoxyribonucleotide synthase [NAD(+)]
|
Colwellia psychrerythraea
|
E. coli
|
|
DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA. DNA ligase Protein, Colwellia psychrerythraea, Recombinant (His) is expressed in E. coli expression system with N-10xHis tag. The predicted molecular weight is 42.1 kDa and the accession number is Q47YI0. |
|
TMPK-00097
|
FGF-21 Protein, Human, Recombinant (mFc & Avi)
FGF-21,PRO10196,FGF21,UNQ3115,成纤维细胞生长因子
|
Human
|
HEK293 Cells
|
|
Fibroblast growth factor 21 (FGF21) is a peptide hormone that is synthesized by several organs and regulates energy homeostasis. Excitement surrounding this relatively recently identified hormone is based on the documented metabolic beneficial effects of FGF21, which include weight loss and improved glycemia. FGF-21 Protein, Human, Recombinant (mFc & Avi) is expressed in HEK293 mammalian cells with N-mFc-Avi tag. The predicted molecular weight is 46.9 kDa and the accession number is Q9NSA1-1. |
|
TMPK-00098
|
FGF-21 Protein, Human, Recombinant (mFc & Avi), Biotinylated
成纤维细胞生长因子,FGF-21,UNQ3115,FGF21,PRO10196
|
Human
|
HEK293 Cells
|
|
Fibroblast growth factor 21 (FGF21) is a peptide hormone that is synthesized by several organs and regulates energy homeostasis. Excitement surrounding this relatively recently identified hormone is based on the documented metabolic beneficial effects of FGF21, which include weight loss and improved glycemia. FGF-21 Protein, Human, Recombinant (mFc & Avi), Biotinylated is expressed in HEK293 mammalian cells with N-mFc-Avi tag. The predicted molecular weight is 46.9 kDa and the accession number i... |
|
TMPJ-00855
|
GLUL Protein, Human, Recombinant (His)
GLUL,GS,Glutamine Synthetase,Glutamate-Ammonia Ligase,GLNS,G...
|
Human
|
E. coli
|
|
Glutamine Synthetase reglutes intracellular concentration of glutamate. Glutamine Synthetase catalyzes the synthesis of glutamine from glutamate and ammonia. Glutamine is an important source of energy and that takes part in cell prolifetation, inhibition of apoptosis, and cell signaling. Glutamine Synthetase is expressed during early fetal stages, and has a role in maintaining body PH by removing ammonia from circulation. Mutations in the GLUL gene are related to congenital glutamine deficiency. |
|
TMPH-03265
|
CMKLR2 Protein, Rat, Recombinant (His)
Chemerin chemokine-like receptor 2,Gpr1,Chemokine-like recep...
|
Rat
|
E. coli
|
|
Receptor for chemoattractant adipokine chemerin/RARRES2 suggesting a role for this receptor in the regulation of inflammation and energy homesotasis. Signals mainly via beta-arrestin pathway. Binding of RARRES2 activates weakly G proteins, calcium mobilization and MAPK1/MAPK3 (ERK1/2) phosphorylation too. Acts also as a receptor for TAFA1, mediates its effects on neuronal stem-cell proliferation and differentiation via the activation of ROCK/ERK and ROCK/STAT3 signaling pathway. |
|
TMPH-02142
|
ERR1 Protein, Human, Recombinant (GST)
Steroid hormone receptor ERR1,Estrogen receptor-like 1,Nucle...
|
Human
|
E. coli
|
|
Binds to an ERR-alpha response element (ERRE) containing a single consensus half-site, 5'-TNAAGGTCA-3'. Can bind to the medium-chain acyl coenzyme A dehydrogenase (MCAD) response element NRRE-1 and may act as an important regulator of MCAD promoter. Binds to the C1 region of the lactoferrin gene promoter. Requires dimerization and the coactivator, PGC-1A, for full activity. The ERRalpha/PGC1alpha complex is a regulator of energy metabolism. Induces the expression of PERM1 in the skeletal muscle. |
|
TMPH-01796
|
NR4A1 Protein, Human, Recombinant (His & Myc)
ST-59,NR4A1,Nuclear hormone receptor NUR/77,Orphan nuclear r...
|
Human
|
E. coli
|
|
Orphan nuclear receptor. May act concomitantly with NURR1 in regulating the expression of delayed-early genes during liver regeneration. Binds the NGFI-B response element (NBRE) 5'-AAAAGGTCA-3'. May inhibit NF-kappa-B transactivation of IL2. Participates in energy homeostasis by sequestrating the kinase STK11 in the nucleus, thereby attenuating cytoplasmic AMPK activation. Plays a role in the vascular response to injury. NR4A1 Protein, Human, Recombinant (His & Myc) is expressed in E. coli expre... |
|
TMPJ-01450
|
SARS-CoV-2 Helicase Protein (His & MBP)
SARS-CoV 2 nsp13,SARS-CoV 2 Helicase
|
SARS-CoV-2
|
E. coli
|
|
The non—structural protein 13 (nsp13) of SARS—CoV 2 is a helicase that separates double—stranded RNA or DNA with a 5'—3' polarity, using the energy of nucleotide hydrolysis. A basic biochemical characterization of nsp13 demonstrated that it can unwind both doublestranded DNA and RNA in a 5’-3’ direction, and it can hydrolyze all deoxyribonucleotide and ribonucleotide triphosphates. Helicases are motor proteins that utilize the energy derived from nucleotide hydrolysisto unwind double-stranded nu... |
|
TMPJ-00149
|
Complement Factor D/CFD Protein, Mouse, Recombinant (His)
C3 convertase activator,28 kDa adipocyte protein,Cfd,Adipsin...
|
Mouse
|
HEK293 Cells
|
|
Complement factor D, also known as adipsin, is a member of the chymotrypsin family of serine proteases, which plays an essential role in host defense as the rate-limiting enzyme in the alternative pathway of complement activation. Complement factor D activates a convertase (C3bBb) responsible for cleavage of the complement protein C3, which leads to the activation of terminal complement component C5-9 to form the membrane attack complex on microbial or cellular surfaces. It also functions in the... |
|
TMPJ-00834
|
ACADM Protein, Human, Recombinant (His)
ACADM,Medium-Chain Specific Acyl-CoA Dehydrogenase Mitochond...
|
Human
|
E. coli
|
|
Medium-Chain Specific Acyl-CoA Dehydrogenase (ACADM) is a mitochondrial fatty acid beta-oxidation that belongs to the acyl-CoA dehydrogenase family. ACADM is a homotetramer enzyme that catalyzes the initial step of the mitochondrial fatty acid beta-oxidation pathway. ACADM is specific for acyl chain lengths of 4 to 16. It is essential for converting these particular fatty acids to energy, especially during fasting periods. Defects in ACADM cause medium-chain acyl-CoA dehydrogenase deficiency, a ... |
|
TMPK-01320
|
GFRAL/GFR alpha-like Protein, Cynomolgus, Recombinant (His & Avi), Biotinylated
GRAL,GFRAL,C6orf144,GFRAL/GFR α-like Protein,GFR α-like,GFR ...
|
Cynomolgus
|
HEK293 Cells
|
|
GFR alpha -like (GDNF receptor-alpha-like) is a distant member of the GDNFR family of proteins. Mature human GFR alpha-like is a 376 amino acid (aa) type I transmembrane protein. It contains a 333 aa extracellular domain, a 20 aa transmembrane domain and a 23 aa cytoplasmic domain.GFRAL is a brainstem-restricted receptor for GDF15 which regulates food intake, energy expenditure and body weight in response to metabolic and toxin-induced stresses. GFRAL/GFR alpha-like Protein, Cynomolgus, Recombin... |
|
TMPK-01052
|
GFRAL/GFR alpha-like Protein, Mouse, Recombinant (His & Avi)
GFRAL/GFR α-like Protein,GFR α-like,GRAL,C6orf144,GFR alpha-...
|
Mouse
|
HEK293 Cells
|
|
GFR alpha -like (GDNF receptor-alpha-like) is a distant member of the GDNFR family of proteins. Mature human GFR alpha-like is a 376 amino acid (aa) type I transmembrane protein. It contains a 333 aa extracellular domain, a 20 aa transmembrane domain and a 23 aa cytoplasmic domain.GFRAL is a brainstem-restricted receptor for GDF15 which regulates food intake, energy expenditure and body weight in response to metabolic and toxin-induced stresses. GFRAL/GFR alpha-like Protein, Mouse, Recombinant (... |
|
TMPK-00284
|
ANGPTL3 Protein, Human, Recombinant (His & Avi)
FHBL2,Angiopoietin-like Protein 3,ANG-5,ANGPTL3,ANGPT5,Angio...
|
Human
|
HEK293 Cells
|
|
ANGPTL3 is a secreted glycoprotein that is structurally related to the angiopoietins. Mature human ANGPTL3 contains an N-terminal coiled coil domain and a C‑terminal fibrinogen-like domain. ANGPTL3 is expressed in the liver from early in development through adulthood. Acts in part as a hepatokine that is involved in regulation of lipid and glucose metabolism. Proposed to play a role in the trafficking of energy substrates to either storage or oxidative tissues in response to food intake. ANGPTL3... |
|
TMPJ-00727
|
PGK1 Protein, Human, Recombinant (His)
Phosphoglycerate kinase 1,Primer recognition protein 2,PGK1,...
|
Human
|
HEK293 Cells
|
|
Phosphoglycerate kinase 1(PGK1) is an enzyme. It is mainly expressed in spermatogonia and Localized on the principle piece in the sperm. Its expression significantly decreased in the testis of elderly men. PGK1 involved in a critical energy-producing process known as glycolysis. It helps carry out a chemical reaction that converts a molecule called 1,3-diphosphoglycerate, which is produced during the breakdown of glucose, to another molecule called 3-phosphoglycerate during glycolysis. PGK1 may ... |
|
TMPJ-00606
|
Leptin Protein, Carassius auratus, Recombinant (His)
OB,Leptin,LEP,Obese Protein,OBS,Obesity Factor
|
Carassius auratus
|
P. pastoris (Yeast)
|
|
Leptin is a hormone secreted from white adipocytes and plays important role in the regulation of food intake and energy balance. Leptin functions via signaling pathways involving OB-R in hypothalamus. In mammals, leptin is mainly produced by the adipose tissue and encodes body fat reserves, acting as a short-term satiety signal. In fish, the presence of a leptin-like peptide was first evidenced by immuno-cross-reactivity, and its existence was certainly demonstrated after the finding by synteny ... |
|
TMPJ-01061
|
Nucleobindin-2 Protein, Human, Recombinant
NUCB2,NEFA,Gastric cancer antigen Zg4,Nesfatin-1,Prepronesfa...
|
Human
|
E. coli
|
|
Nesfatin-1 is a metabolic polypeptide encoded in the N-terminal region of the precursor protein, Nucleobindin2 (NUCB2). Nesfatin-1 is a neuropeptide produced in the hypothalamus of mammals. It participates in the regulation of hunger and fat storage. Nesfatin-1 is also expressed in other areas of the brain, and in pancreatic islets β-cells, gastric endocrine cells and adipocytes. Nesfatin-1 suppresses food intake and can regulate energy metabolism in a Leptin independent manner. Nesfatin-1 may ... |
|
TMPJ-01324
|
UBA5 Protein, Human, Recombinant (His)
Ubiquitin-like modifier-activating enzyme 5,UBE1DC1,UFM1-act...
|
Human
|
E. coli
|
|
UBA5 is a member of the ubiquitin-activating E1 family and UBA5 subfamily. Ubiquitin and ubiquitin-like proteins are recognized as covalently conjugated to various cellular substrates by a three-step enzymatic pathway. The ubiquitin-activating enzyme (E1) has a vital role in the first step of ubiquitination pathway to activate ubiquitin or ubiquitin-like proteins. UBA5 activates ubiquitin-fold modifier 1, a ubiquitin-like post-translational modifier protein, via the formation of a high-energy th... |
|
TMPK-01058
|
GFRAL/GFR alpha-like Protein, Human, Recombinant (His & Avi)
GFR alpha-like,GFRAL,C6orf144,GRAL,GFR α-like,GFRAL/GFR α-li...
|
Human
|
HEK293 Cells
|
|
GFR alpha -like (GDNF receptor-alpha-like) is a distant member of the GDNFR family of proteins. Mature human GFR alpha-like is a 376 amino acid (aa) type I transmembrane protein. It contains a 333 aa extracellular domain, a 20 aa transmembrane domain and a 23 aa cytoplasmic domain.GFRAL is a brainstem-restricted receptor for GDF15 which regulates food intake, energy expenditure and body weight in response to metabolic and toxin-induced stresses. GFRAL/GFR alpha-like Protein, Human, Recombinant (... |
|
TMPK-01060
|
GFRAL/GFR alpha-like Protein, Human, Recombinant (hFc)
GFRAL,GRAL,C6orf144,GFR alpha-like,GFR α-like,GFRAL/GFR α-li...
|
Human
|
HEK293 Cells
|
|
GFR alpha -like (GDNF receptor-alpha-like) is a distant member of the GDNFR family of proteins. Mature human GFR alpha-like is a 376 amino acid (aa) type I transmembrane protein. It contains a 333 aa extracellular domain, a 20 aa transmembrane domain and a 23 aa cytoplasmic domain.GFRAL is a brainstem-restricted receptor for GDF15 which regulates food intake, energy expenditure and body weight in response to metabolic and toxin-induced stresses. GFRAL/GFR alpha-like Protein, Human, Recombinant (... |
|
TMPK-00285
|
ANGPTL3 Protein, Human, Recombinant (His & Avi), Biotinylated
ANGPTL3,FHBL2,ANGPT5,Angiopoietin-5,ANL3,ANG-5,Angiopoietin-...
|
Human
|
HEK293 Cells
|
|
ANGPTL3 is a secreted glycoprotein that is structurally related to the angiopoietins. Mature human ANGPTL3 contains an N-terminal coiled coil domain and a C‑terminal fibrinogen-like domain. ANGPTL3 is expressed in the liver from early in development through adulthood. Acts in part as a hepatokine that is involved in regulation of lipid and glucose metabolism. Proposed to play a role in the trafficking of energy substrates to either storage or oxidative tissues in response to food intake. ANGPTL3... |
|
TMPK-01059
|
GFRAL/GFR alpha-like Protein, Human, Recombinant (His & Avi), Biotinylated
GFRAL/GFR α-like Protein,C6orf144,GFRAL,GFR alpha-like,GFR α...
|
Human
|
HEK293 Cells
|
|
GFR alpha -like (GDNF receptor-alpha-like) is a distant member of the GDNFR family of proteins. Mature human GFR alpha-like is a 376 amino acid (aa) type I transmembrane protein. It contains a 333 aa extracellular domain, a 20 aa transmembrane domain and a 23 aa cytoplasmic domain.GFRAL is a brainstem-restricted receptor for GDF15 which regulates food intake, energy expenditure and body weight in response to metabolic and toxin-induced stresses. GFRAL/GFR alpha-like Protein, Human, Recombinant (... |
|
TMPY-02421
|
PARP3 Protein, Human, Recombinant (His & GST)
ARTD3,IRT1,ADPRTL2,ADPRTL3,poly (ADP-ribose) polymerase fami...
|
Human
|
Baculovirus Insect Cells
|
|
Poly(ADP-ribose) polymerase 3 (PARP3) is an important member of the PARP family and shares high structural similarities with both PARP1 and PARP2. Poly(ADP-ribose) polymerase 3 (PARP3), a critical player in cellular response to DNA double-strand breaks (DSBs), plays an essential role in the maintenance of genome integrity. The ADP ribosyl transferase [poly(ADP-ribose) polymerase] ARTD3(PARP3) is a newly characterized member of the ARTD(PARP) family that catalyzes the reaction of ADP ribosylation... |
|
TMPJ-00997
|
GALK1 Protein, Human, Recombinant (His)
Galactokinase,Galactose Kinase,GALK1,GALK
|
Human
|
E. coli
|
|
Galactokinase belongs to the GHMP kinase family and GalK subfamily. Galactokinase is more important to the galactose metabolism pathway. It modifies galactose to create a similar molecule called Galactose-1-Phosphate.Thus, a series of additional steps converts Galactose-1-Phosphate to another simple sugar Glucose, which is the main energy source for most cells. Galactokinase deficiency results in Galactosemia II, an autosomal recessive deficiency characterized by congenital cataracts during infa... |
|
TMPH-03740
|
DCL Protein, Bacillus subtilis, Recombinant (His)
DCL,D-alanine--poly(phosphoribitol) ligase subunit 1,dltA,DA...
|
Bacillus subtilis
|
E. coli
|
|
Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP-dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the... |
|
TMPK-01319
|
GFRAL/GFR alpha-like Protein, Cynomolgus, Recombinant (His & Avi)
GFR alpha like,GRAL,GFRAL,C6orf144,GFRAL/GFR α-like Protein,...
|
Cynomolgus
|
HEK293 Cells
|
|
GFR alpha -like (GDNF receptor-alpha-like) is a distant member of the GDNFR family of proteins. Mature human GFR alpha-like is a 376 amino acid (aa) type I transmembrane protein. It contains a 333 aa extracellular domain, a 20 aa transmembrane domain and a 23 aa cytoplasmic domain.GFRAL is a brainstem-restricted receptor for GDF15 which regulates food intake, energy expenditure and body weight in response to metabolic and toxin-induced stresses. GFRAL/GFR alpha-like Protein, Cynomolgus, Recombin... |
|
TMPK-01053
|
GFRAL/GFR alpha-like Protein, Mouse, Recombinant (His & Avi), Biotinylated
GRAL,GFRAL/GFR α-like Protein,GFR alpha-like,GFR α-like,GFRA...
|
Mouse
|
HEK293 Cells
|
|
GFR alpha -like (GDNF receptor-alpha-like) is a distant member of the GDNFR family of proteins. Mature human GFR alpha-like is a 376 amino acid (aa) type I transmembrane protein. It contains a 333 aa extracellular domain, a 20 aa transmembrane domain and a 23 aa cytoplasmic domain.GFRAL is a brainstem-restricted receptor for GDF15 which regulates food intake, energy expenditure and body weight in response to metabolic and toxin-induced stresses. GFRAL/GFR alpha-like Protein, Mouse, Recombinant (... |
|
TMPJ-00052
|
Leptin Protein, Mouse, Recombinant
OB,Obesity Factor,OBS,LEP,Obese Protein,Leptin
|
Mouse
|
E. coli
|
|
Leptin is a hormone secreted from white adipocytes and plays important role in the regulation of food intake and energy balance. Leptin functions via signaling pathways involving OB-R in hypothalamus. Animal models have revealed the influence of Leptin in reducing body weight and regulating blood glucose level. When mutations are introduced in obese gene, mice with impaired function of leptin are massively obese and in high risk of diabetes. Leptin deficiency reduces metablic rate. Leptin defici... |
|
TMPJ-00836
|
G6PD Protein, Human, Recombinant (His)
Glucose-6-Phosphate 1-Dehydrogenase,G6PD
|
Human
|
HEK293 Cells
|
|
Glucose-6-Phosphate 1-Dehydrogenase (G6PD) is a cytosolic enzyme that belongs to the glucose-6-phosphate dehydrogenase family. G6PD participates in the pentose phosphate pathway that supplies reducing energy to cells by maintaining the level of the co-enzyme nicotinamide adenine dinucleotide phosphate (NADPH). G6PD produces pentose sugars for nucleic acid synthesis and main producer of NADPH reducing power. NADPH in turn maintains the level of glutathione in these cells that helps protect the re... |
|
TMPJ-01473
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BMP-7 Protein, Human, Recombinant
Eptotermin alfa,OP-1,OP1,Osteogenic protein 1,Bone morphogen...
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Human
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HEK293 Cells
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Bone morphogenetic protein 7 (BMP7), also known as osteogenic protein-1 (OP-1) is a member of Transforming growth factor-β (TGF-β) family of proteins. Bone morphogenetic proteins were discovered in 1965 by Marshal Urist, of which BMP7 is of particular interest in this review being a leptin-independent anorexinogen and having role in energy expenditure in the brown adipose tissue, which makes it a potential target for preventing/treating obesity. As it has been established that Obesity displays a... |
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TMPY-04477
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CKMT1A Protein, Human, Recombinant (His)
creatine kinase, mitochondrial 1A,CKMT,CKMT1A,CKMT1
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Human
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Baculovirus Insect Cells
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CKMT1A belongs to the ATP:guanido phosphotransferase family. It contains 1 phosphagen kinase C-terminal domain and 1 phosphagen kinase N-terminal domain. CKMT1A gene is one of two genes that encodes the ubiquitous mitochondrial creatine kinase (CKMT1). CKMT1 is responsible for the transfer of high energy phosphate from mitochondria to the cytosolic carrier, creatine. It belongs to the creatine kinase isoenzyme family. It exists as two isoenzymes, sarcomeric MtCK (CKMT2) and ubiquitous MtCK, enco... |
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TMPH-02245
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HADHB Protein, Human, Recombinant (GST)
HADHB,TP-beta,Trifunctional enzyme subunit beta, mitochondri...
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Human
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E. coli
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Mitochondrial trifunctional enzyme catalyzes the last three of the four reactions of the mitochondrial beta-oxidation pathway. The mitochondrial beta-oxidation pathway is the major energy-producing process in tissues and is performed through four consecutive reactions breaking down fatty acids into acetyl-CoA. Among the enzymes involved in this pathway, the trifunctional enzyme exhibits specificity for long-chain fatty acids. Mitochondrial trifunctional enzyme is a heterotetrameric complex compo... |
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TMPJ-00552
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LILRB2/CD85d/ILT4 Protein, Human, Recombinant (Avi & His), Biotinylated
Leukocyte Immunoglobulin-Like Receptor 2,Monocyte/Macrophage...
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Human
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HEK293 Cells
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Members of the immunoglobulin-like transcript (ILT) family are activating and inhibitory immunoreceptors whose genes are located same locus that encodes killer cell Ig-like receptors (KIR). Leukocyte Immunoglobulin-Like Receptor Subfamily B Member 2 (LIR-2) is a type I transmembrane protein. LIR-2 is expressed primarily on monocytes and dendritic cells (DC). Human LIR-2 is produced as a 598 amino acino acid precursor including a 21 aa signal sequence, a 440 aa extracellular domain (ECD), a 21 aa... |
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TMPJ-01034
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TIM Protein, Human, Recombinant (His)
TPI1,TPI,Triose-Phosphate Isomerase,Triosephosphate Isomeras...
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Human
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E. coli
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Triose-phosphate isomerase, also named Triose-phosphate isomerase, TPI and TIM, is an enzyme that catalyzes the reversible interconversion of the triose phosphate isomers dihydroxyacetone phosphate and D-glyceraldehyde 3-phosphate. TPI has been found in nearly every organism searched for the enzyme, including animals such as mammals and insects as well as in fungi, plants, and bacteria. However, some bacteria that do not perform glycolysis, like ureaplasmas, lack TPI. TPI plays an important role... |
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