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Targets Recommended: Epigenetic Reader Domain Discoidin Domain Receptor (DDR) Others

713

抑制剂 & 化合物

13

天然产物

2

化合物库

1125

重组蛋白

5

同位素标记化合物

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Cat. No.	Product Name
L1710	抗COVID-19化合物库		1133 compounds
	1133 种对SARS-CoV-2有抑制作用或潜在抑制作用的化合物集合，可用于高通量和高内涵筛选；
L8720	细胞焦亡化合物库		1066 compounds
	1066 种细胞焦亡相关的化合物，可以用于细胞焦亡相关研究。

化合物库

抗COVID-19化合物库

Cat.No: L1710

Compounds: 1133

细胞焦亡化合物库

Cat.No: L8720

Compounds: 1066

Cat. No.	Product Name	Target	Signaling Pathways
TP1699L	SEB Domain 144-153 acetate SEB Domain 144-153 acetate(210229-94-0 free base)	Others	Others
	SEB Domain 144-153 acetate(210229-94-0 free base) 是葡萄球菌肠毒素 B 结构域氨基酸残基 163-172。它已被证明可抑制多种葡萄球菌肠毒素、SEA、SEE 和 TSST-1 的转胞吞作用。
TP1699	SEB Domain (144-153) SEB Domain 144-153
	SEB Domain (144-153) peptide is Staphylococcal Enterotoxin B domain amino acid residue 163-172. SEB Domain (144-153) has been shown to inhibit transcytosis of multiple staphylococcal enterotoxins, SEA, SEE, and TSST-1.
TP2208	PDZ1 Domain inhibitor peptide	Others	Others
	Novel cyclic peptide that disrupts interaction between GluR6 and PSD-95
T36656	Anti-Spike-RBD Single Domain mAb
	The Anti-Spike-RBD Single Domain mAb is a monoclonal antibody derived from CHO cells in Alpaca. It is composed of VHH-huFc and exhibits a strong affinity for the SARS-CoV-2 RBD. [1]
TP2163	SEB Domain 144-153 TFA(210229-94-0 free base) SEB Domain (144-153) (TFA)	Others	Others
	SEB Domain 144-153 TFA is Staphylococcal Enterotoxin B domain amino acid residue 144-153. It inhibits transcytosis of multiple staphylococcal enterotoxins, SEE, SEA, and TSST-1.
T40409	Tau Peptide (275-305) (Repeat 2 domain)
	Tau Peptide (275-305), also known as the R2 domain fragment, represents the second repeat unit of the microtubule-binding domain of the Alzheimer's tau peptide. Tau Peptide (275-305) is considered crucial in determining the biochemical characteristics of the complete tau protein.
T82261	Grb2 SH2 domain inhibitor 1	Others	Others
	Grb2 SH2 domain inhibitor 1是构象受限环细胞穿透肽（CPP），主要用作环状肽基抑制剂，包含特定d-Pro-l-Pro基序环（AFΦrpPRRFQ），其中Φ为l-萘基丙氨酸，r为d-精氨酸，p为d-脯氨酸。
T75838	PDZ1 Domain inhibitor peptide TFA
	PDZ1 Domain inhibitor peptide TFA，一种环状肽，以 β-Ala 内酰胺侧链为接头，专一性靶向 PSD-95 的 PDZ1 域。此化合物能干扰 GluR6/PSD-95 间的相互作用，通过与 GluR6 的 C 末端竞争，抑制其在 PDZ1 域的结合。
T77994	Grb2 SH2 domain inhibitor 1 TFA
	Grb2 SH2 domain inhibitor 1 TFA 是构象受限的环细胞穿透肽（CPP），含有d-Pro-l-Pro基序环（AFΦrpPRRFQ），Φ为l-萘基丙氨酸，r为d-精氨酸，p为d-脯氨酸，主要用作环状肽基抑制剂。
T80521	Caveolin-1 (82-101) amide (human, mouse, rat) Caveolin-1 scaffolding domain peptide	c-Met/HGFR	Tyrosine Kinase/Adaptors
	Caveolin-1 (82-101) amide (human, mouse, rat) (Caveolin-1 scaffolding domain peptide) 是抑制酪氨酸激酶的肽，可逆转多器官衰老相关的有害变化。
T2072	BET bromodomain inhibitor	Epigenetic Reader Domain	Chromatin/Epigenetic
	BET bromodomain inhibitor 是 BET 的一种有效抑制剂。
T15424	GSK1379725A	Epigenetic Reader Domain	Chromatin/Epigenetic
	GSK1379725A 是一种选择性 BPTF 配体，Kd 为 2.8 μM。
T11925	M‑89	Epigenetic Reader Domain; Histone Methyltransferase	Chromatin/Epigenetic
	M-89 可抑制 Menin-MLL 蛋白之间的相互作用，有研究混合谱系白血病的潜力。它是一种强特异性 menin 抑制剂，结合到 menin 的Kd 值为 1.4 nM。
T4495	dBET1	Epigenetic Reader Domain; PROTACs	Chromatin/Epigenetic; PROTAC
	dBET1 是一种由 BRD4 抑制剂 JQ1 与 NSC 527179 衍生物通过 linker 产生的 PROTAC，可诱导 BRD4 降解。它是由Cereblon 配体和BRD4配体相连的PROTAC，其EC50值为 430 nM。
T5440	Dbet57	Epigenetic Reader Domain; PROTACs	Chromatin/Epigenetic; PROTAC
	dBET57 是基于 PROTAC 技术的 BRD4 异双功能降解剂，对 BRD4BD1 有显著降解作用，DC50/5h 为 500 nM。
T5130	dBET6	Apoptosis; Epigenetic Reader Domain; PROTACs	Apoptosis; Chromatin/Epigenetic; PROTAC
	dBET6 是一种基于 PROTAC 的选择性和细胞渗透性 BET 降解剂，IC50值为 14 nM。它具有抗肿瘤活性。
T5362	Y06036	Epigenetic Reader Domain	Chromatin/Epigenetic
	Y06036 是一种选择性 BET 抑制剂，具有抗肿瘤活性，可与 BRD4(1)溴结构域结合，Kd 值为 82 nM。
T9109	SSAA09E2	RAAS; SARS-CoV	Endocrinology/Hormones; Microbiology/Virology
	SSAA09E2 是一种新型的SARS-CoV 复制抑制剂，通过阻断SARS-S 与SARS-CoV 受体血管紧张素转换酶-2 的早期相互作用发挥作用。
T13363	Y06137	Epigenetic Reader Domain; PKC	Chromatin/Epigenetic; Cytoskeletal Signaling
	Y06137 是一种有效的特异性 BET 抑制剂，对 BRD4(1) 溴结构域的 Kd 为 81 nM。 Y06137可用于去势抵抗性前列腺癌治疗的研究。
T3973	PF-CBP1	Epigenetic Reader Domain	Chromatin/Epigenetic
	PF-CBP1 是一种高选择性的 CREB 结合蛋白 (CREBBP) 溴结构域抑制剂。它抑制 CREBBP (IC50: 125 nM) 和 p300 溴结构域 (IC50: 363 nM)。
T17311	(+)-JQ1 PA	Epigenetic Reader Domain	Chromatin/Epigenetic
	(+)-JQ1 PA 是一种溴结构域和末端外 (BET) 抑制剂 JQ1 的衍生物，IC50 为 10.4 nM。
T9568	SGC-SMARCA-BRDVIII	Epigenetic Reader Domain	Chromatin/Epigenetic
	SGC-SMARCA-BRDVIII 是SMARCA2/4和PB1(5)选择性抑制剂，其Kd 值分别为 35 nM，36 nM 和 13 nM。它还抑制PB1(2)和PB1(3)，Kd 值分别为 3.7 和 2.0 μM。它可阻断 3T3-L1 鼠成纤维细胞的脂肪生成。
TQ0253	PLX51107	Epigenetic Reader Domain	Chromatin/Epigenetic
	PLX51107 是一种选择性 BET 抑制剂，与 CBP 和 EP300 的结构域相互作用。它对 BRD2、BRD3、BRD4 和 BRDT 的 BD1 结构域的亲和力Kd 值分别为 1.6、2.1、1.7 和 5 nM，BD2 结构域亲和力Kd 值分别为 5.9、6.2、6.1 和 120 nM。
TQ0083	NI-57	Epigenetic Reader Domain	Chromatin/Epigenetic
	NI-57 是溴结构域和植物同源锌指结构域 (BRPF) 蛋白家族的一种抑制剂，对 BRPF1、BRPF2 (BRD1) 和 BRPF3 的 IC50值分别为 3.1、46 和 140 nM。
T16072	MI-538	Epigenetic Reader Domain; Histone Methyltransferase	Chromatin/Epigenetic
	MI-538是一种menin 和MLL 融合蛋白相互作用的抑制剂，IC50值为 21 nM。
T16321	NI-42	Epigenetic Reader Domain	Chromatin/Epigenetic
	NI-42 是一种用于 BRPF 的结构正交化学探针，是有偏向性的BRPFs 溴结构域 (BRD)抑制剂，BRPF1、2和3的IC50为7.9、48和260 nM; BRPF1、2和3的Kd 值为40、210和940 nM，与非分类 IV BRD 蛋白相比具有很好的选择性。
T3311	GSK6853	Epigenetic Reader Domain	Chromatin/Epigenetic
	GSK6853 是一种强选择性RPF1乙酰赖氨酸抑制剂，pKd 为9.5，其选择性是其它的乙酰赖氨酸的 1600 倍。
T19935	XD14	Epigenetic Reader Domain	Chromatin/Epigenetic
	XD14 是BET 抑制剂，其与 BRD2、BRD3 和 BRD4 的结合常数分别为 170 nM、380 nM 和 160 nM。它具有抗肿瘤活性。
T1854	MS436	Epigenetic Reader Domain	Chromatin/Epigenetic
	MS436 是溴结构域抑制剂，作用于 BRD4 BrD1的Ki 为 30 到 50 nM 之间，比作用于 BrD2 选择性高 10 倍。
T2127	OF-1	Epigenetic Reader Domain	Chromatin/Epigenetic
	OF-1 是溴结构域的一种抑制剂，其对TRIM24 和BRPF1B 的IC50值分别为270 mM 和1.2 μM。
T12112	MS402	Epigenetic Reader Domain	Chromatin/Epigenetic
	MS402 是一种新型 BD1 选择性 BET BrD 抑制剂，阻断 Th17 细胞分化并改善小鼠结肠炎，对BRD4(BD1)、BRD4(BD2)、BRD3(BD1)、BRD3(BD2)、BRD2(BD1)和BRD2(BD2)的Ki 分别为 77 、718、110、200、83 和 240 nM。
T11136	E-7386 E7386	Epigenetic Reader Domain	Chromatin/Epigenetic
	E-7386 是是一种有口服活性的 CBP/-catenin 调节剂。
T17697	BRD7-IN-1	Epigenetic Reader Domain	Chromatin/Epigenetic
	BRD7-IN-1 是一种修饰的 BI7273 衍生物 (BRD7/9 抑制剂)。BRD7-IN-1 通过与 VHL 配体连接形成 PROTAC VZ185。VZ185 抑制 BRD7/9 的 DC50分别是 4.5 nM 和1.8 nM。
T5442	A1874	Epigenetic Reader Domain; PROTACs	Chromatin/Epigenetic; PROTAC
	A1874 是一种基于 nutlin 的 BRD4 降解 PROTAC，可诱导细胞中的 BRD4 降解，DC50值为 32 nM。它有效抑制许多癌细胞系的增殖。
TQ0058	MI-463	Epigenetic Reader Domain; Histone Methyltransferase	Chromatin/Epigenetic
	MI-463 是一种有口服活性的menin-mLL 相互作用的高效小分子抑制剂，IC50为15.3 nM。
TQ0069	MI-503	Epigenetic Reader Domain; Histone Methyltransferase	Chromatin/Epigenetic
	MI-503 是一种高效且可口服的 menin-mLL 相互作用抑制剂。
T14685	BMS-986158	Epigenetic Reader Domain	Chromatin/Epigenetic
	BMS-986158 是一种BET 抑制剂，在 MDA-MB231 三阴性乳腺癌细胞和 NCI-H211 小细胞肺癌细胞中，对 BET 的IC50分别为 5 和 6.6 nM。
T9749	FHD-286	Epigenetic Reader Domain	Chromatin/Epigenetic
	FHD-286 是 BRM/BRG1 ATPase 的抑制剂，可用于治疗 BAF 相关疾病如急性髓性白血病的研究。
T9339	Stafia-1	STAT	JAK/STAT signaling; Stem Cells
	Stafia-1 是STAT5a 抑制剂，Ki 为 10.9 μM，IC50 为 22.2 μM。它与 STAT5b 和其他 STAT 家族成员相比，显示出高选择性。
T6783	BI-7273	Epigenetic Reader Domain	Chromatin/Epigenetic
	BI7273 是一种选择性的可细胞透过BRD9抑制剂，IC50和Kd 分别为 19 和 0.75 nM。它对 BRD7 的作用较强，IC50和Kd 值分别为 117 和 0.3 nM。
T5417	INCB-057643	Apoptosis; Epigenetic Reader Domain	Apoptosis; Chromatin/Epigenetic
	INCB-057643 是一种有效的、选择性的和口服生物可利用的 BET 抑制剂。
T5434	ARV-825	Epigenetic Reader Domain; PROTACs	Chromatin/Epigenetic; PROTAC
	ARV-825 是一种双功能 PROTAC，蛋白水解靶向嵌合体，将 BRD4 募集到 E3 泛素连接酶大脑中，导致 BRD4 在所有测试的 BL 细胞系中快速、有效和延长降解。对 BRD4 的 BD1 和 BD2 结构域具有高亲和力，Kd 值分别为 90 和 28 nM。
T5435	ARV-771	Epigenetic Reader Domain; PROTACs	Chromatin/Epigenetic; PROTAC
	ARV-771 是基于 PROTAC 技术的有效 BET 降解剂，对 BRD2(1)、BRD2(2)、BRD3(1)、BRD3(2)、BRD4 (1) 和 BRD4(2)的 Kd 分别为 34、4.7、8.3、7.6、9.6 和 7.6 nM。
T3337	Ddr1-In-1	Discoidin Domain Receptor (DDR)	Tyrosine Kinase/Adaptors
	DDR1-IN-1 是一种特异性的 DDR1 受体酪氨酸激酶抑制剂，选择性是 DDR2 的 3 倍左右。
T6939	PFI-3 PFI 3	Epigenetic Reader Domain	Chromatin/Epigenetic
	PFI-3是一种选择性，可渗透细胞的SMARCA2/4溴结构域抑制剂，Kd 值为89 nM，可延迟和预防乳腺癌。
T83739	Myr-Tat-CBD3 TFA Myr-Tat-Calcium Channel-binding Domain 3,N-myristate-Tat-CBD3
	Myr-Tat-CBD3是一种抑制N型电压门控钙通道Cav2.2与collapsin response mediator protein 2 (CRMP2)之间的蛋白-蛋白相互作用的抑制剂。在10 µM的浓度下，该化合物能够约81%地抑制Cav2.2-CRMP2相互作用，并在大鼠初级背根神经节(DRG)神经元中抑制钾诱导的钙流入（IC50约为2.8 µM）。在20 µM的浓度下，Myr-Tat-CBD3能抑制钙电流，但不影响钠电流，在初级DRG神经元中表现出这种特性。经过脊髓内给药，myr-Tat-CBD3（20 µg/5 µl）能够防止大鼠脚掌撤回潜伏期因carrageenan注射而减少。此外，Myr-Tat-CBD3减少大鼠因线索引起的寻求可卡因行为的复发。
T3624	A-366 A 366,A366	Epigenetic Reader Domain; Histone Methyltransferase	Chromatin/Epigenetic
	A-366 是一种高选择性的肽竞争性组蛋白甲基转移酶 G9a 抑制剂，对 G9a 和 GLP 的 IC50分别为 3.3 和 38 nM。它比其他 21 种甲基转移酶具有 1000 倍以上的选择性。它是 Spindlin1-H3K4me3相互作用的抑制剂，IC50为182.6 nM。它对人 H3R 表现出很高的亲和力，Ki 值为 17 nM，在组胺能和多巴胺能受体家族的亚群间表现出亚型选择性。
T9063	Clathrin-IN-1	HIV Protease	Microbiology/Virology; Proteases/Proteasome
	Clathrin-IN-1 是一种网格蛋白抑制剂，可通过与网格蛋白的末端域相关联来抑制网格蛋白介导的内吞作用，有潜力用于抗癌的研究。
T17350	ACBI1	Apoptosis; Epigenetic Reader Domain; PROTACs	Apoptosis; Chromatin/Epigenetic; PROTAC
	ACBI1 是一种基于PROTAC 技术的 BAF ATPase 亚基SMARCA2和SMARCA4降解剂，也是 PBAF 成员PBRM1的降解剂。它由一个 bromodomain 配体、linker 和 E3 泛素连接酶von Hippel-Lindau 构成，能诱导抗增殖作用和凋亡。
T6786	BI-9564 BI 9564,BI9564	Epigenetic Reader Domain	Chromatin/Epigenetic
	BI-9564 是一种选择性的且可透过细胞的 BRD9/BRD7溴结构域抑制剂，IC50分别为 75 和 3.4 μM，Kd 为 14 和 239 nM。它对 BET 家族的 IC50值大于 100 μM。

化合物

SEB Domain 144-153 acetate

Cat.No: TP1699L

Synonym: SEB Domain 144-153 acetate(210229-94-0 free base)

Target: Others

SEB Domain (144-153)

Cat.No: TP1699

Synonym: SEB Domain 144-153

PDZ1 Domain inhibitor peptide

Cat.No: TP2208

Target: Others

Anti-Spike-RBD Single Domain mAb

Cat.No: T36656

SEB Domain 144-153 TFA(210229-94-0 free base)

Cat.No: TP2163

Synonym: SEB Domain (144-153) (TFA)

Target: Others

Tau Peptide (275-305) (Repeat 2 domain)

Cat.No: T40409

Grb2 SH2 domain inhibitor 1

Cat.No: T82261

Target: Others

PDZ1 Domain inhibitor peptide TFA

Cat.No: T75838

Grb2 SH2 domain inhibitor 1 TFA

Cat.No: T77994

Caveolin-1 (82-101) amide (human, mouse, rat)

Cat.No: T80521

Synonym: Caveolin-1 scaffolding domain peptide

Target: c-Met/HGFR

BET bromodomain inhibitor

Cat.No: T2072

Target: Epigenetic Reader Domain

Cat.No: T15424

Target: Epigenetic Reader Domain

Cat.No: T11925

Target: Epigenetic Reader Domain, Histone Methyltransferase

Cat.No: T4495

Target: Epigenetic Reader Domain, PROTACs

Cat.No: T5440

Target: Epigenetic Reader Domain, PROTACs

Cat.No: T5130

Target: Apoptosis, Epigenetic Reader Domain, PROTACs

Cat.No: T5362

Target: Epigenetic Reader Domain

Cat.No: T9109

Target: RAAS, SARS-CoV

Cat.No: T13363

Target: Epigenetic Reader Domain, PKC

Cat.No: T3973

Target: Epigenetic Reader Domain

Cat.No: T17311

Target: Epigenetic Reader Domain

SGC-SMARCA-BRDVIII

Cat.No: T9568

Target: Epigenetic Reader Domain

Cat.No: TQ0253

Target: Epigenetic Reader Domain

Cat.No: TQ0083

Target: Epigenetic Reader Domain

Cat.No: T16072

Target: Epigenetic Reader Domain, Histone Methyltransferase

Cat.No: T16321

Target: Epigenetic Reader Domain

Cat.No: T3311

Target: Epigenetic Reader Domain

Cat.No: T19935

Target: Epigenetic Reader Domain

Cat.No: T1854

Target: Epigenetic Reader Domain

Cat.No: T2127

Target: Epigenetic Reader Domain

Cat.No: T12112

Target: Epigenetic Reader Domain

Cat.No: T11136

Synonym: E7386

Target: Epigenetic Reader Domain

Cat.No: T17697

Target: Epigenetic Reader Domain

Cat.No: T5442

Target: Epigenetic Reader Domain, PROTACs

Cat.No: TQ0058

Target: Epigenetic Reader Domain, Histone Methyltransferase

Cat.No: TQ0069

Target: Epigenetic Reader Domain, Histone Methyltransferase

Cat.No: T14685

Target: Epigenetic Reader Domain

Cat.No: T9749

Target: Epigenetic Reader Domain

Cat.No: T9339

Target: STAT

Cat.No: T6783

Target: Epigenetic Reader Domain

Cat.No: T5417

Target: Apoptosis, Epigenetic Reader Domain

Cat.No: T5434

Target: Epigenetic Reader Domain, PROTACs

Cat.No: T5435

Target: Epigenetic Reader Domain, PROTACs

Cat.No: T3337

Target: Discoidin Domain Receptor (DDR)

Cat.No: T6939

Synonym: PFI 3

Target: Epigenetic Reader Domain

Myr-Tat-CBD3 TFA

Cat.No: T83739

Synonym: Myr-Tat-Calcium Channel-binding Domain 3,N-myristate-Tat-CBD3

Cat.No: T3624

Synonym: A 366,A366

Target: Epigenetic Reader Domain, Histone Methyltransferase

Cat.No: T9063

Target: HIV Protease

Cat.No: T17350

Target: Apoptosis, Epigenetic Reader Domain, PROTACs

Cat.No: T6786

Synonym: BI 9564,BI9564

Target: Epigenetic Reader Domain

Cat. No.	Product Name	Target	Signaling Pathways
TN2269	Tetramethylcurcumin	Apoptosis; STAT	Apoptosis; JAK/STAT signaling; Stem Cells
	Tetramethylcurcumin 是一种新型姜黄素类似物，是一种有效的 STAT3 磷酸化、DNA 结合活性和体外反式激活抑制剂。它具有抗炎和抗癌作用。
T6389	Anacardic Acid 漆树酸,6-pentadecylsalicylic Acid,Hydroginkgolic acid	Others; Epigenetic Reader Domain; Histone Acetyltransferase; Antibacterial	Chromatin/Epigenetic; Microbiology/Virology; Others
	Anacardic Acid (6-pentadecylsalicylic Acid) 是从腰果壳中提取液中分离到的酸类物质，是一种组蛋白乙酰转移酶抑制剂，对 p300 和 PCAF 的 IC50值分别为 ∼8.5 μM 和 ∼5 μM。
T1516	Curcumin Diferuloylmethane,Natural Yellow 3,姜黄素,Indian Saffron,Turmeric yellow	Mitophagy; Epigenetic Reader Domain; Ferroptosis; Influenza Virus; Nrf2; Histone Acetyltransferase; HDAC; Autophagy	Apoptosis; Autophagy; Chromatin/Epigenetic; DNA Damage/DNA Repair; Immunology/Inflammation; Microbiology/Virology
	Curcumin (Natural Yellow 3) 属于酚类天然产物，是一种组蛋白乙酰化转移酶 p300/CREB 的抑制剂 (IC50=25 μM)，具有特异性。Curcumin 具有抗肿瘤、抗炎和抗氧化等多种药理活性。
T3862	Irigenin	NF-κB; Integrin	Cytoskeletal Signaling; NF-κB
	Irigenin 可通过特异性和选择性地阻断 Extra Domain A 域的 C-C 环上α9β1和α4β1整合素结合位点，介导其抗转移作用。可通过增强胃癌细胞中促凋亡分子的表达来敏化 TRAIL 诱导的凋亡，具有抗癌作用。
TN2285	DL-Tryptophan (±)-Tryptophan,Tryptophan,DL-色氨酸	Serotonin Transporter; Endogenous Metabolite	Metabolism; Neuroscience
	DL-Tryptophan ((±)-Tryptophan) 是内源性代谢产物的一种。
T6396	(R)-(-)-Gossypol acetic acid (-)-Gossypol acetic acid,AT-101 (acetic acid),(R)-Gossypol acetic acid,AT101醋酸,AT101,AT101 acetate	BCL; Autophagy	Apoptosis; Autophagy
	(R)-(-)-Gossypol acetic acid (AT101 acetate) 是天然产物 Gossypol 的左旋异构体，与 Bcl-2、Bcl-xL 和 Mcl-1 结合，Ki 为 0.32 μM、0.48 μM 和 0.18 μM。
T2730	Gossypol (acetic acid) (±)-Gossypol-acetic acid,Pogosin,AT101,醋酸棉酚,乙酸棉子酚,Gossypol acetic acid	BCL	Apoptosis
	Gossypol acetic acid (AT101) 是一种从棉籽中分离出来的多酚天然产物，分别与 Bcl-xL 蛋白和 Bcl-2蛋白结合，Ki 值分别为 0.5-0.6 μM 和 0.2-0.3 mM。
T6343	Geldanamycin 格尔德霉素,NSC 122750	HSP; Influenza Virus; Tyrosine Kinases; Antibacterial; Antibiotic	Cytoskeletal Signaling; Metabolism; Microbiology/Virology; Tyrosine Kinase/Adaptors
	Geldanamycin 是一种 HSP90 抑制剂（Kd：1.2 μM），可特异性破坏糖皮质激素受体 (GR)/HSP 的结合。
TL0017	Aristolactam AIIIa	MAPK; CDK	Cell Cycle/Checkpoint; MAPK
	Aristolactam AIIIa is a new type of Plk1 inhibitors, targeting the Polo Box domain (PBD), it has anti-tumor activity. Aristolactam IIIa shows inhibition of platelet aggregation induced by collagen or arachidonic acid.
T14831	Bryostatin 1	HIV Protease; PKC	Chromatin/Epigenetic; Cytoskeletal Signaling; Microbiology/Virology; Proteases/Proteasome
	Bryostatin 1 is a natural macrolide isolated from the bryozoan Bugula neritina and is a CNS)permeable PKC modulator. Bryostatin 1 binds to the isolated C1 domain of Munc13-1 and the full-length Munc13-1 protein (Kis: 8.07 nM and 0.45 nM).
T16719	Radicicol 根赤壳菌素,Monorden	HSP	Cytoskeletal Signaling; Metabolism
	Radicicol is an antifungal antibiotic, impairs mitochondrial replication by targeting P. falciparum topoisomerase VIB. Radicicol is an inhibitor of Hsp90 (IC50: 1 μM). Radicicol binds to the ATPase domain of Hsp90 and prevents maturation of Hsp90 clients,
T73876	Sanggenon G	Others	Others
	Sanggenon G 是一种具有细胞渗透性的有效的 X 连锁凋亡抑制蛋白 (XIAP) 抑制剂。Sanggenon G 特异性结合XIAP 的 BIR3 结构域，结合亲和力为 34.26 μM。Sanggenon G 增强caspase 激活。
TN3616	Cedrelone	Apoptosis; MMP; Antifection	Apoptosis; Microbiology/Virology; Proteases/Proteasome
	Cedrelone 是一种柠檬苦素类化合物，是一种吩嗪生物合成样结构域蛋白 (PBLD) 激活剂。Cedrelone 可诱导癌细胞凋亡 (apoptosis)。Cedrelone 是一种非常有效的细胞凋亡诱导剂，它能导致细胞周期停止。Cedrelone 具有杀虫活性，可抑制 P. saucia 的箭毒生长，并可抑制乳草蝽（Oncopeltus fasciatus）的蜕皮。Cedrelone具有抗肿瘤作用，对SMMC-7721、A-549、MCF-7 和 SW480 等癌细胞株具有显著的细胞毒性。

天然产物

Tetramethylcurcumin

Cat.No: TN2269

Target: Apoptosis, STAT

Cat.No: T6389

Synonym: 漆树酸,6-pentadecylsalicylic Acid,Hydroginkgolic acid

Target: Others, Epigenetic Reader Domain, Histone Acetyltransferase, Antibacterial

Cat.No: T1516

Synonym: Diferuloylmethane,Natural Yellow 3,姜黄素,Indian Saffron,Turmeric yellow

Target: Mitophagy, Epigenetic Reader Domain, Ferroptosis, Influenza Virus, Nrf2, Histone Acetyltransferase, HDAC, Autophagy

Cat.No: T3862

Target: NF-κB, Integrin

Cat.No: TN2285

Synonym: (±)-Tryptophan,Tryptophan,DL-色氨酸

Target: Serotonin Transporter, Endogenous Metabolite

(R)-(-)-Gossypol acetic acid

Cat.No: T6396

Synonym: (-)-Gossypol acetic acid,AT-101 (acetic acid),(R)-Gossypol acetic acid,AT101醋酸,AT101,AT101 acetate

Target: BCL, Autophagy

Gossypol (acetic acid)

Cat.No: T2730

Synonym: (±)-Gossypol-acetic acid,Pogosin,AT101,醋酸棉酚,乙酸棉子酚,Gossypol acetic acid

Target: BCL

Cat.No: T6343

Synonym: 格尔德霉素,NSC 122750

Target: HSP, Influenza Virus, Tyrosine Kinases, Antibacterial, Antibiotic

Aristolactam AIIIa

Cat.No: TL0017

Target: MAPK, CDK

Cat.No: T14831

Target: HIV Protease, PKC

Cat.No: T16719

Synonym: 根赤壳菌素,Monorden

Target: HSP

Cat.No: T73876

Target: Others

Cat.No: TN3616

Target: Apoptosis, MMP, Antifection

Species：

Expression System：

Tag：

Cat. No.	Product Name	Species	Expression System
TMPY-02869	MMP-12 Protein, Human, Recombinant (catalytic domain) HME,ME,MMP-12,MME,matrix metallopeptidase 12	Human	E. coli
	Matrix metalloproteinases (MMPs) are a family of zinc-dependent endopeptidases that degrade components of the extracellular matrix (ECM) and play essential roles in various physiological processes such as morphogenesis, differentiation, angiogenesis, and tissue remodeling, as well as pathological processes including inflammation, arthritis, cardiovascular diseases, pulmonary diseases, and tumor invasion. Macrophage Metalloelastase, also known as Matrix metalloproteinase-12, Macrophage elastase, ...
TMPY-03835	CDCP1 Protein, Rhesus, Recombinant (His) CUB domain containing protein 1	Rhesus	HEK293 Cells
	CDCP1 Protein, Rhesus, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 73.4 kDa and the accession number is F6TPM5.
TMPY-02882	HIV-1 (group M, subtype CRF07_BC) gp140 Protein (His) CUB domain containing protein 1	HIV	HEK293 Cells
	HIV-1 (group M, subtype CRF07_BC) gp140 Protein (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 78.2 kDa.
TMPY-04625	SEMA3A Protein, Mouse, Recombinant (His) SemD,Semad,Hsema-I,SEMA1,coll-1,sema domain, immuno...	Mouse	HEK293 Cells
	SEMA3A Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 61.6 kDa and the accession number is A0A803Z7F8.
TMPY-02360	SEMA3A Protein, Mouse, Recombinant (hFc) Semad,Hsema-I,coll-1,sema domain, immunoglobulin	Mouse	HEK293 Cells
	SEMA3A Protein, Mouse, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 87.7 kDa and the accession number is O08665.
TMPY-01460	ABHD4 Protein, Human, Recombinant (His) abhydrolase domain containing 4,ABH4	Human	Baculovirus Insect Cells
	Abhydrolase domain containing 4 (ABHD4), also known as alpha/beta-hydrolase 4 (ABH4) , or lyso-N-acylphosphatidylethanolamine lipase, which belongs to the ABHD4/ABHD5 subfamily of peptidase S33 family. Abhydrolase domain containing (ABHD) gene was a small group belongs to alpha/beta hydrolase superfamily. Known members of this group are all found to be involved in important biochemical processes and related to various diseases. The alpha/beta-hydrolase 4 (ABH4) is a lysophospholipase/phospholipa...
TMPY-01859	LYPD3 Protein, Human, Recombinant (His) LY6/PLAUR domain containing 3,C4.4A	Human	HEK293 Cells
	LYPD3 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 28.3 kDa and the accession number is B2RBR3.
TMPY-00124	SEMA3A Protein, Human, Recombinant (hFc) sema domain, immunoglobulin domain (Ig), s...	Human	HEK293 Cells
	SEMA3A Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 87.7 kDa and the accession number is Q14563.
TMPY-04802	VEGFR2/KDR Protein, Human, Recombinant (Domain 2&3, hFc) kinase insert domain receptor,CD309,VEGFR2,FLK1,Flk...	Human	HEK293 Cells
	VEGFR2/KDR Protein, Human, Recombinant (Domain 2&3, hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 50.4 kDa and the accession number is P35968-1.
TMPY-04298	CDCP1 Protein, Human, Recombinant (His) TRASK,CD318,CUB domain containing protein 1,SIMA135	Human	HEK293 Cells
	CDCP1 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 36.4 kDa and the accession number is Q9H5V8-3.
TMPY-06074	B7-H4 Protein, Cynomolgus, Rhesus, Recombinant (His) V-set domain containing T cell activation inhibitor...	Cynomolgus,Rhesus	HEK293 Cells
	B7-H4 Protein, Cynomolgus, Rhesus, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 26.8 kDa and the accession number is A0A2K5U6P5-1.
TMPY-01907	VSIG4 Protein, Human, Recombinant (His) Z39IG,CRIg,V-set and immunoglobulin domain containi...	Human	HEK293 Cells
	VSIG4 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 30.5 kDa and the accession number is Q9Y279-1.
TMPY-04796	VEGFR2/KDR Protein, Human, Recombinant (Domain 2&3, His) FLK1,kinase insert domain receptor,CD309,VEGFR2,Flk...	Human	HEK293 Cells
	VEGFR2/KDR Protein, Human, Recombinant (Domain 2&3, His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 24.8 kDa and the accession number is P35968-1.
TMPY-02785	Tetranectin Protein, Mouse, Recombinant (His) C-type lectin domain family 3, member B,Tna	Mouse	HEK293 Cells
	Tetranectin Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 20.7 kDa and the accession number is P43025.
TMPY-04795	VEGFR2/KDR Protein, Human, Recombinant (Domain 1&2&3, His) kinase insert domain receptor,VEGFR2,FLK1,Flk-1,CD3...	Human	HEK293 Cells
	VEGFR2/KDR Protein, Human, Recombinant (Domain 1&2&3, His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 35.9 kDa and the accession number is P35968-1.
TMPY-04794	VEGFR2/KDR Protein, Human, Recombinant (Domain 1&2&3, hFc) VEGFR,kinase insert domain receptor,Flk-1,VEGFR2,FL...	Human	HEK293 Cells
	VEGFR2/KDR Protein, Human, Recombinant (Domain 1&2&3, hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 61.5 kDa and the accession number is P35968-1.
TMPY-02361	VEGFR2/KDR Protein, Human, Recombinant (His) VEGFR2,kinase insert domain receptor,VEGFR,FLK1,Flk...	Human	HEK293 Cells
	VEGFR2/KDR Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 84.6 kDa and the accession number is P35968-1.
TMPY-00586	CLEC-2 Protein, Mouse, Recombinant (hFc) 1810061I13Rik,Clec2,C-type lectin domain family 1, ...	Mouse	HEK293 Cells
	CLEC-2 Protein, Mouse, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 49.1 kDa and the accession number is Q9JL99-1.
TMPY-05581	TIM-4/TIMD4 Protein, Human, Recombinant (His), Biotinylated T-cell immunoglobulin and mucin domain containing 4...	Human	HEK293 Cells
	TIM-4/TIMD4 Protein, Human, Recombinant (His), Biotinylated is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 32.7 kDa and the accession number is AAH08988.1.
TMPY-01894	SIGIRR Protein, Human, Recombinant (His) TIR8,single immunoglobulin and toll-interleukin 1 receptor (...	Human	HEK293 Cells
	SIGIRR Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 14 kDa and the accession number is Q6IA17-1.
TMPY-01882	HE4 Protein, Human, Recombinant (His) dJ461P17.6,EDDM4,WAP four-disulfide core domain 2,W...	Human	HEK293 Cells
	HE4 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 11.3 kDa and the accession number is A0A384MTN6.
TMPK-00398	FGFR2 beta (IIIb) Domain Protein, Human, Recombinant (Avi) Fibroblast growth factor receptor 2,CD332,FGFR2 β (IIIb)	Human	HEK293 Cells
	FGFR2 beta (IIIb) Domain Protein, Human, Recombinant (Avi) is expressed in HEK293 mammalian cells with C-Avi tag. The predicted molecular weight is 15.49 kDa and the accession number is P21802-3.
TMPY-05586	CD28H/TMIGD2 Protein, Human, Recombinant (His & Avi), Biotinylated TMIGD2,IGPR-1,transmembrane and immunoglobulin domain	Human	HEK293 Cells
	The orthologue of human IGPR-1 is found only in eukaryotes, including primates, the guinea pig, canines, felines, dolphins, bovines, the llama, bats, the common shrew, and horses. Of interest, the IGPR-1 gene is absent in mouse and rat genomes. The immunoglobulin domain of IGPR-1 was predicted to be Ig V (variable) fold and was found to be highly similar to the Ig domain of myelin-associated glycoprotein.Cancer ImmunotherapyImmune CheckpointImmunotherapyTargeted Therapy. CD28H/TMIGD2 Protein, Hu...
TMPY-05322	B7-H4 Protein, Mouse, Recombinant (His) BC032925,B7h4,B7x,V-set domain containing T cell ac...	Mouse	HEK293 Cells
	B7-H4 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 26.6 kDa and the accession number is Q7TSP5.
TMPY-02971	CLEC10A Protein, Human, Recombinant (hFc) HML2,CD301,CLECSF13,HML,MGL,C-type lectin domain fa...	Human	HEK293 Cells
	CLEC10A Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 54.6 kDa and the accession number is Q8IUN9-2.
TMPH-00003	LASP1 Protein, Human, Recombinant (His) LIM and SH3 domain protein 1,Metastatic lymph node ...	Human	P. pastoris (Yeast)
	LASP1 Protein, Human, Recombinant (His) is expressed in yeast with C-6xHis tag. The predicted molecular weight is 31.2 kDa; 43 kDa, reducing conditions and the accession number is Q14847.
TMPY-02848	Adiponectin Protein, Human, Recombinant (hFc) ADPN,adiponectin, C1Q and collagen domain containin...	Human	HEK293 Cells
	Adiponectin Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 51.6 kDa and the accession number is Q15848.
TMPK-00399	FGFR2 beta (IIIb) Domain Protein, Human, Recombinant (Avi), Biotinylated Keratinocyte growth factor receptor,K-sam,BEK,FGFR2 β (IIIb)...	Human	HEK293 Cells
	FGFR2 beta (IIIb) Domain Protein, Human, Recombinant (Avi), Biotinylated is expressed in HEK293 mammalian cells with C-Avi tag. The predicted molecular weight is 15.49 kDa and the accession number is P21802-3.
TMPY-05556	Adiponectin Protein, Human, Recombinant (His) ADPN,Adiponectin,APM1,adiponectin, C1Q and collagen doma...	Human	Baculovirus Insect Cells
	Adiponectin Protein, Human, Recombinant (His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 26 kDa and the accession number is A8K660.
TMPY-06076	LILRA2/CD85h/ILT1 Protein, Human, Recombinant (hFc) LIR7,LIR-7,ILT1,CD85H,leukocyte immunoglobulin-like receptor...	Human	HEK293 Cells
	LILRA2/CD85h/ILT1 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 73.7 kDa and the accession number is Q8N149-1.
TMPK-00599	Fc gamma RIIIA/CD16a (V176) Domain 2 Protein, Human, Recombinant (mFc) FCGR3,IGFR3,FcR-10,Fc γ RIIIA/CD16a (V176) Domain 2...	Human	HEK293 Cells
	Human Fc gamma RIIIA/CD16a Protein is a receptor for the Fc region of IgG. Binds complexed or aggregated IgG and also monomeric IgG. Mediates antibody-dependent cellular cytotoxicity (ADCC) and other antibody-dependent responses, such as phagocytosis. Fc gamma RIIIA/CD16a (V176) Domain 2 Protein, Human, Recombinant (mFc) is expressed in HEK293 mammalian cells with C-mFc tag. The predicted molecular weight is 35.29 kDa and the accession number is AAH17865.
TMPY-01289	DDR1 Protein, Human, Recombinant (His) RTK6,DDR,TRKE,PTK3,NTRK4,NEP,PTK3A,MCK10,EDDR1,HGK2,CD167,CA...	Human	HEK293 Cells
	DDR1 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 45.7 kDa and the accession number is A0A024RCQ1.
TMPY-03524	B7-H4 Protein, Human, Recombinant (His) PRO1291,B7X,B7H4,B7-H4,VCTN1,B7S1,B7h.5,V-set domain	Human	HEK293 Cells
	B7-H4 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 26.8 kDa and the accession number is Q7Z7D3-1.
TMPY-01032	CD299 Protein, Human, Recombinant (hFc) LSIGN,CLEC4M,C-type lectin domain family 4 member M...	Human	HEK293 Cells
	CD299 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 65 kDa and the accession number is Q9H2X3-1.
TMPY-03613	COMMD8 Protein, Human, Recombinant (His) COMM domain containing 8	Human	E. coli
	COMMD8 is a member of the COMMD family. Members of this family are a group of evolutionary conserved proteins that share a common COMM domain at the extreme C-terminus, which provides an interface for protein-protein interactions. Most COMMD proteins play a role in the regulation of NF˚B and, despite their similarities, seem to function in unique and non-redundant pathways. COMMD proteins may also play a role in the function of epithelial sodium channels, cell proliferation, copper homeostasis a...
TMPY-03877	ADAM8/CD156a Protein, Rhesus, Recombinant (His) ADAM metallopeptidase domain 8	Rhesus	HEK293 Cells
	ADAM8/CD156a Protein, Rhesus, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 53.6 kDa and the accession number is XP_002805919.1.
TMPY-02678	VEGFR2/KDR Protein, Rat, Recombinant (His) kinase insert domain receptor	Rat	HEK293 Cells
	VEGFR2/KDR Protein, Rat, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 84.3 kDa and the accession number is A6HDB7.
TMPY-05382	VEGFR2/KDR Protein, Cynomolgus, Recombinant (His) kinase insert domain receptor	Cynomolgus	HEK293 Cells
	VEGFR2/KDR Protein, Cynomolgus, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 84.7 kDa and the accession number is G7P5T2.
TMPY-03202	VEGFR2/KDR Protein, Rat, Recombinant (hFc) kinase insert domain receptor	Rat	HEK293 Cells
	VEGFR2/KDR Protein, Rat, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 110 kDa and the accession number is Q5PQU0.
TMPK-00949	CDH17 Domain 7 Protein, Human, Recombinant (hFc) CDH16,P130,MGC142024,Cdh17,FLJ26931,Cadherin-17,MGC138218,ca...	Human	HEK293 Cells
	Liver-intestine cadherin (CDH17) has been known to function as a tumor stimulator and diagnostic marker for almost two decades.In vivo studies showed CDH17 knockout resulted in apoptotic PC tumor death through activating caspase-3 activity. Taken together, CDH17 functions as an oncogenic molecule critical to PC growth by regulating tumor apoptosis signaling pathways and CDH17 could be targeted to develop an anti-PC therapeutic approach. CDH17 Domain 7 Protein, Human, Recombinant (hFc) is express...
TMPY-02719	NRG1 alpha Protein, Human, Recombinant (EGF Domain, hFc) HRG1,NRG1-IT2,HRGA,NRG1 α,HGL,neuregulin 1,SMDF,MSTP131,NDF,...	Human	HEK293 Cells
	NRG1 alpha Protein, Human, Recombinant (EGF Domain, hFc) is expressed in HEK293 mammalian cells with Fc tag. The predicted molecular weight is 35.8 kDa and the accession number is Q02297-1.
TMPY-03308	ADAM17 Protein, Rat, Recombinant (His) ADAM metallopeptidase domain 17	Rat	HEK293 Cells
	ADAM17 is a member of the ADAM protein family of disintegrins and metalloproteases. ADAM17 is ubiquitously expressed in the human colon, with increased activity in the colonic mucosa of patients with ulcerative colitis, a main form of inflammatory bowel disease. The expression of ADAM17 may be inhibited by ethanol. It is involved in the processing of tumor necrosis factor alpha (TNF-α) at the surface of the cell, and from within the intracellular membranes of the trans-Golgi network. ADAM1...
TMPY-00047	Dengue virus DENV-2 (Strain New Guinea C) Capsid protein/DENV-C Protein (His) death-domain associated protein	DENV	E. coli
	Dengue virus DENV-2 (Strain New Guinea C) Capsid protein/DENV-C Protein (His) is expressed in E. coli expression system with His tag. The predicted molecular weight is 14 kDa and the accession number is W0GCK5.
TMPY-01843	SEMA6A Protein, Human, Recombinant (His) HT018,VIA,sema domain, transmembrane domain	Human	HEK293 Cells
	SEMA6A, the first identified class 6 semaphorin, is contributed to regulate vascular development and adult angiogenesis. SEMA6A could inhibit proliferation, migration, and invasion in different glioma cell lines. That SEMA6A may be a potential prognostic biomarker in the treatment of GBM. Among different semaphorins tested by reverse transcriptase-polymerase chain reaction in human immune cells, the expression of class 6 transmembrane semaphorin SEMA6A was restricted to dendritic cells (DCs).
TMPY-00059	TM2D1 Protein, Human, Recombinant (mFc) TM2 domain containing 1,BBP	Human	HEK293 Cells
	TM2D1 Protein, Human, Recombinant (mFc) is expressed in HEK293 mammalian cells with mFc tag. The predicted molecular weight is 35.1 kDa and the accession number is Q9BX74.
TMPY-00425	HIV-1 (group M, subtype A, strain 92UG037.1) gp140 Protein (hFc) CUB domain containing protein 1	HIV	HEK293 Cells
	HIV-1 (group M, subtype A, strain 92UG037.1) gp140 Protein (hFc) is expressed in HEK293 mammalian cells with Fc tag. The predicted molecular weight is 97.4 kDa and the accession number is P90249.
TMPY-02957	DYDC2 Protein, Human, Recombinant (GST) DPY30 domain containing 2	Human	E. coli
	DPY30 domain containing 2 belongs to the dpy-30 family. Dumpy-30 family members act as determinants of male fertility and interaction partners of metal-responsive transcription factor 1 (MTF-1) in Drosophila. MTF-1 plays a key role in transition metal detoxification and homeostasis. It binds to metal response elements (MREs). Two candidate dMTF-1 interactors are related to the small regulatory protein Dumpy-30 (Dpy-30) of the worm C. elegans. Dpy-30 is the founding member of a protein family inv...
TMPY-02092	CLEC12A/MICL/CLL-1 Protein, Human, Recombinant (His) HECL,CLL-1,CD303,PRO34150,DCAL-2,CLL1,DLEC,CLECSF11,CLECSF7,...	Human	HEK293 Cells
	CLEC12A/MICL/CLL-1 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 41~45 kDa and the accession number is EAW96132.1.
TMPY-02213	RAIDD Protein, Human, Recombinant (His) RAIDD,MRT34,CASP2 and RIPK1 domain containing adapt...	Human	E. coli
	Death domain-containing protein CRADD, also known as Caspase and RIP adapter with death domain, RIP-associated protein with a death domain, CRADD and RAIDD, is a protein which is constitutively expressed in most tissues, with particularly high expression in adult heart, testis, liver, skeletal muscle, fetal liver and kidney. CRADD / RAIDD contains oneCARD domain and onedeath domain. CRADD / RAIDD contains a death domain involved in the binding of RIP protein. The CARD domain mediates the ...
TMPY-00414	LILRA5/CD85f/ILT11 Protein, Human, Recombinant (His) ILT-11,CD85F,LIR-9,LIR9,LILRB7,CD85,ILT11,leukocyte immunogl...	Human	HEK293 Cells
	LILRA5/CD85f/ILT11 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 26.7 kDa and the accession number is A6NI73-1.
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重组蛋白

MMP-12 Protein, Human, Recombinant (catalytic domain)

Cat.No: TMPY-02869

Species: Human

Expression System: E. coli

CDCP1 Protein, Rhesus, Recombinant (His)

Cat.No: TMPY-03835

Species: Rhesus

Expression System: HEK293 Cells

HIV-1 (group M, subtype CRF07_BC) gp140 Protein (His)

Cat.No: TMPY-02882

Species: HIV

Expression System: HEK293 Cells

SEMA3A Protein, Mouse, Recombinant (His)

Cat.No: TMPY-04625

Species: Mouse

Expression System: HEK293 Cells

SEMA3A Protein, Mouse, Recombinant (hFc)

Cat.No: TMPY-02360

Species: Mouse

Expression System: HEK293 Cells

ABHD4 Protein, Human, Recombinant (His)

Cat.No: TMPY-01460

Species: Human

Expression System: Baculovirus Insect Cells

LYPD3 Protein, Human, Recombinant (His)

Cat.No: TMPY-01859

Species: Human

Expression System: HEK293 Cells

SEMA3A Protein, Human, Recombinant (hFc)

Cat.No: TMPY-00124

Species: Human

Expression System: HEK293 Cells

VEGFR2/KDR Protein, Human, Recombinant (Domain 2&3, hFc)

Cat.No: TMPY-04802

Species: Human

Expression System: HEK293 Cells

CDCP1 Protein, Human, Recombinant (His)

Cat.No: TMPY-04298

Species: Human

Expression System: HEK293 Cells

B7-H4 Protein, Cynomolgus, Rhesus, Recombinant (His)

Cat.No: TMPY-06074

Species: Cynomolgus,Rhesus

Expression System: HEK293 Cells

VSIG4 Protein, Human, Recombinant (His)

Cat.No: TMPY-01907

Species: Human

Expression System: HEK293 Cells

VEGFR2/KDR Protein, Human, Recombinant (Domain 2&3, His)

Cat.No: TMPY-04796

Species: Human

Expression System: HEK293 Cells

Tetranectin Protein, Mouse, Recombinant (His)

Cat.No: TMPY-02785

Species: Mouse

Expression System: HEK293 Cells

VEGFR2/KDR Protein, Human, Recombinant (Domain 1&2&3, His)

Cat.No: TMPY-04795

Species: Human

Expression System: HEK293 Cells

VEGFR2/KDR Protein, Human, Recombinant (Domain 1&2&3, hFc)

Cat.No: TMPY-04794

Species: Human

Expression System: HEK293 Cells

VEGFR2/KDR Protein, Human, Recombinant (His)

Cat.No: TMPY-02361

Species: Human

Expression System: HEK293 Cells

CLEC-2 Protein, Mouse, Recombinant (hFc)

Cat.No: TMPY-00586

Species: Mouse

Expression System: HEK293 Cells

TIM-4/TIMD4 Protein, Human, Recombinant (His), Biotinylated

Cat.No: TMPY-05581

Species: Human

Expression System: HEK293 Cells

SIGIRR Protein, Human, Recombinant (His)

Cat.No: TMPY-01894

Species: Human

Expression System: HEK293 Cells

HE4 Protein, Human, Recombinant (His)

Cat.No: TMPY-01882

Species: Human

Expression System: HEK293 Cells

FGFR2 beta (IIIb) Domain Protein, Human, Recombinant (Avi)

Cat.No: TMPK-00398

Species: Human

Expression System: HEK293 Cells

CD28H/TMIGD2 Protein, Human, Recombinant (His & Avi), Biotinylated

Cat.No: TMPY-05586

Species: Human

Expression System: HEK293 Cells

B7-H4 Protein, Mouse, Recombinant (His)

Cat.No: TMPY-05322

Species: Mouse

Expression System: HEK293 Cells

CLEC10A Protein, Human, Recombinant (hFc)

Cat.No: TMPY-02971

Species: Human

Expression System: HEK293 Cells

LASP1 Protein, Human, Recombinant (His)

Cat.No: TMPH-00003

Species: Human

Expression System: P. pastoris (Yeast)

Adiponectin Protein, Human, Recombinant (hFc)

Cat.No: TMPY-02848

Species: Human

Expression System: HEK293 Cells

FGFR2 beta (IIIb) Domain Protein, Human, Recombinant (Avi), Biotinylated

Cat.No: TMPK-00399

Species: Human

Expression System: HEK293 Cells

Adiponectin Protein, Human, Recombinant (His)

Cat.No: TMPY-05556

Species: Human

Expression System: Baculovirus Insect Cells

LILRA2/CD85h/ILT1 Protein, Human, Recombinant (hFc)

Cat.No: TMPY-06076

Species: Human

Expression System: HEK293 Cells

Fc gamma RIIIA/CD16a (V176) Domain 2 Protein, Human, Recombinant (mFc)

Cat.No: TMPK-00599

Species: Human

Expression System: HEK293 Cells

DDR1 Protein, Human, Recombinant (His)

Cat.No: TMPY-01289

Species: Human

Expression System: HEK293 Cells

B7-H4 Protein, Human, Recombinant (His)

Cat.No: TMPY-03524

Species: Human

Expression System: HEK293 Cells

CD299 Protein, Human, Recombinant (hFc)

Cat.No: TMPY-01032

Species: Human

Expression System: HEK293 Cells

COMMD8 Protein, Human, Recombinant (His)

Cat.No: TMPY-03613

Species: Human

Expression System: E. coli

ADAM8/CD156a Protein, Rhesus, Recombinant (His)

Cat.No: TMPY-03877

Species: Rhesus

Expression System: HEK293 Cells

VEGFR2/KDR Protein, Rat, Recombinant (His)

Cat.No: TMPY-02678

Species: Rat

Expression System: HEK293 Cells

VEGFR2/KDR Protein, Cynomolgus, Recombinant (His)

Cat.No: TMPY-05382

Species: Cynomolgus

Expression System: HEK293 Cells

VEGFR2/KDR Protein, Rat, Recombinant (hFc)

Cat.No: TMPY-03202

Species: Rat

Expression System: HEK293 Cells

CDH17 Domain 7 Protein, Human, Recombinant (hFc)

Cat.No: TMPK-00949

Species: Human

Expression System: HEK293 Cells

NRG1 alpha Protein, Human, Recombinant (EGF Domain, hFc)

Cat.No: TMPY-02719

Species: Human

Expression System: HEK293 Cells

ADAM17 Protein, Rat, Recombinant (His)

Cat.No: TMPY-03308

Species: Rat

Expression System: HEK293 Cells

Dengue virus DENV-2 (Strain New Guinea C) Capsid protein/DENV-C Protein (His)

Cat.No: TMPY-00047

Species: DENV

Expression System: E. coli

SEMA6A Protein, Human, Recombinant (His)

Cat.No: TMPY-01843

Species: Human

Expression System: HEK293 Cells

TM2D1 Protein, Human, Recombinant (mFc)

Cat.No: TMPY-00059

Species: Human

Expression System: HEK293 Cells

HIV-1 (group M, subtype A, strain 92UG037.1) gp140 Protein (hFc)

Cat.No: TMPY-00425

Species: HIV

Expression System: HEK293 Cells

DYDC2 Protein, Human, Recombinant (GST)

Cat.No: TMPY-02957

Species: Human

Expression System: E. coli

CLEC12A/MICL/CLL-1 Protein, Human, Recombinant (His)

Cat.No: TMPY-02092

Species: Human

Expression System: HEK293 Cells

RAIDD Protein, Human, Recombinant (His)

Cat.No: TMPY-02213

Species: Human

Expression System: E. coli

LILRA5/CD85f/ILT11 Protein, Human, Recombinant (His)

Cat.No: TMPY-00414

Species: Human

Expression System: HEK293 Cells

--------- 更多 ---------

Cat. No.	Product Name	Target	Signaling Pathways
T14687	Deucravacitinib BMS-986165	Tyrosine Kinases; JAK; IFNAR; Interleukin	Angiogenesis; Chromatin/Epigenetic; Immunology/Inflammation; JAK/STAT signaling; Stem Cells; Tyrosine Kinase/Adaptors
	Deucravacitinib (BMS-986165) 是一种高选择性、口服生物可利用的变构 TYK2 抑制剂，用于治疗自身免疫性疾病。它通过稳定调节 JH2 结构域来阻断受体介导的 Tyk2 激活，可抑制IL-12/23和 I 型IFN 途径。它选择性结合 TYK2 假激酶 (JH2) 结构域，IC50为1.0 nM。
T13235	Tyk2-IN-7	Others	Others
	Tyk2-IN-7 is an inhibitor of TYK2 JH2, binds to the TYK2 JH2 domain (IC50: 0.00053 μM; Ki.app: 0.00007 μM).
T70394	Deucravacitinib HCl
	Deucravacitinib HCl is a Highly Potent and Selective Allosteric Inhibitor of TYK2. BMS-986165 Blocks Il-12, IL-23 and type I Interferon Signaling and Provides for Robust Efficacy in Preclinical Models of Inflammatory Bowel Disease. MS-986165 potently binds to the Tyk2 pseudokinase domain (Ki = 0.02 nM), and is highly selective against a panel of 265 kinases and pseudokinases. The compound potently inhibited IL-23-, IL-12-, and Type I interferon-driven cellular signaling and transcriptional resp...
T37044	1,2-Dioleoyl-rac-glycerol-13C3 1,2-Dioleoyl-rac-glycerol-13C3
	1,2-Dioleoyl-rac-glycerol-13C3 is intended for use as an internal standard for the quantification of 1,2-dioleoyl-rac-glycerol by GC- or LC-MS. 1,2-dioleoyl-rac-glycerol is a diacylglycerol that contains oleic acid at the sn-1 and sn-2 positions. It effectively binds the C1 domain to activate conventional protein kinase C forms and serves as a substrate for diacylglycerol kinases and multisubstrate lipid kinase.1,2,3 \|1. Yamaguchi, Y., Shirai, Y., Matsubara, T., et al. Phosphorylation and up-reg...
T70882	Orlistat-d3
	Orlistat-d3 is intended for use as an internal standard for the quantification of orlistat by GC- or LC-MS. Orlistat is a digestive lipase inhibitor. It inhibits diacylglycerol lipase α (DAGLα), DAGLβ, α/β-hydrolase domain-containing protein 12 (ABHD12), ABHD16A, and platelet-activating factor acetylhydrolase (PAF-AH; IC50s = 0.06, 0.1, 0.08, 0.03, and 0.05 µM, respectively), as well as pancreatic lipase and hormone-sensitive lipase (IC50s = 0.65 and 2.1 µg/ml, respectively) but does not inhibit...

同位素标记化合物

Deucravacitinib

Cat.No: T14687

Synonym: BMS-986165

Target: Tyrosine Kinases, JAK, IFNAR, Interleukin

Cat.No: T13235

Target: Others

Deucravacitinib HCl

Cat.No: T70394

1,2-Dioleoyl-rac-glycerol-13C3

Cat.No: T37044

Synonym: 1,2-Dioleoyl-rac-glycerol-13C3

Cat.No: T70882

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