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Search Results for " diuretic "

Targets Recommended: Antifungal

93

抑制剂 & 化合物

16

天然产物

1

化合物库

1

重组蛋白

9

同位素标记化合物

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Cat. No.	Product Name
L7110	抗高血压化合物库		678 compounds
	678 种高血压相关的小分子，用于高通量和高内涵筛选；

化合物库

抗高血压化合物库

Cat.No: L7110

Compounds: 678

Cat. No.	Product Name	Target	Signaling Pathways
T8129	Potassium acetate Diuretic salt,Potassium ethanoate,乙酸钾	Antifungal	Microbiology/Virology
	Potassium acetate (Diuretic salt) 是一种钾盐，能够用于补充电解质，恢复水电解质平衡，也能用于制备细菌碱性裂解的中和液，以及纯化 DNA 和蛋白质。
T10441	Azosemide	Na-K-Cl cotransporter	Membrane transporter/Ion channel
	Azosemide 是磺胺类环利尿剂和NKCC1抑制剂，对 hNKCC1A 和 NKCC1B 的IC50分别为 0.246 和 0.197 µM。
T21469	Cyclopenthiazide Cyclomethiazide,Su-8341,SU 8341,环戊噻嗪	Others	Others
	Cyclopenthiazide (Cyclomethiazide) 是一种噻嗪类利尿剂，用于治疗高血压和心力衰竭。减少钙离子和尿酸的排泄，增加钠和钾离子的排泄。
T36125	Tienilic Acid	P450	Metabolism
	Tienilic Acid 是一种具有一定肝毒性的排尿酸利尿剂
T0114	Trichlormethiazide Naqua,Metahydrin,三氯噻嗪,Trichlormetazid	ATPase; Carbonic Anhydrase	Membrane transporter/Ion channel; Metabolism
	Trichlormethiazide (Naqua) 是一种口服具有活力的噻嗪类利尿剂，具有降压作用。它能够提高急性肾功能衰竭大鼠的尿量、Na 和 K 排泄，并有改善降低的肌酐清除率。
T6086	Clopamide Brinaldix,Adurix,Aquex,氯帕胺	Sodium Channel	Membrane transporter/Ion channel
	Clopamide (Brinaldix) 是口服有效的噻嗪类利尿剂，对钠耦合的氯离子共转运蛋白 SLC12A3有抑制作用。Clopamide 在高血压和心力衰竭中具有研究价值。
T1410	Torsemide AC-4464,JDL-464,托拉塞米,Torasemide	Na-K-Cl cotransporter	Membrane transporter/Ion channel
	Torsemide (AC-4464) 是具有口服活性的亨氏环利尿剂，也具有抗醛固酮和血管舒张活性。它可用于研究心力衰竭、肾脏疾病、肝硬化。
T6288	Mozavaptan 莫扎伐坦,OPC31260l,OPC-31260	Vasopressin Receptor	GPCR/G Protein
	Mozavaptan (OPC-31260) 是 benzazepine 衍生物，是一种竞争性加压素受体拮抗剂，作用于 V1 和 V2 受体，IC50 分别为 1.2 μM 和 14 nM。它可在体内拮抗精氨酸加压素的抗利尿作用，可用于低钠血症、抗利尿激素不适当综合征和充血性心力衰竭的研究。
T6551	Isosorbide Devicoran,Isobide,异山梨酯,异山梨醇,Hydronol,Dianhydro-D-glucitol,D-Isosorbide	Others	Others
	Isosorbide (Devicoran) 是一种血管舒张剂，也是一种高渗利尿剂，口服具有活性。可用于研究心力衰竭和心绞痛(胸痛)。
T3096	Canrenoate potassium 坎利酸钾,Potassium aldadiene,Canrenoic acid potassium salt,Potassium canrenoate,Soldactone	Glucocorticoid Receptor	Endocrinology/Hormones
	Canrenoate potassium (Soldactone) 是一种有效的竞争性盐皮质激素受体 (mineralocorticoid receptor) 拮抗剂，是一种释放 canrenone 的前药。它作为一种利尿剂，用于高血压的研究。
T17266	Xipamide 希伯胺,Diurexan,Aquaphor	Others	Others
	Xipamide (Diurexan) 是一种磺胺类利尿剂，具有抗高血压特性。Xipamide 可选择性地抑制阴离子交换器。
T0275	Meticrane 美替克仑,Fontiliz,Arresten,蒲硫杂茶磺胺	Chloride channel; Sodium Channel	Membrane transporter/Ion channel
	Meticrane (Arresten) 是一种磺胺类衍生物，具有类似噻嗪类利尿剂的活性，可于研究原发性高血压。
TP1114L	Leucokinin VIII acetate Leucokinin 8	Others	Others
	Leucokinin VIII acetate (Leucokinin 8) 是一种从蟑螂头部提取物中分离的利尿八肽。
T27323	FK-453 FK453,FK 453	Adenosine Receptor	GPCR/G Protein; Neuroscience
	FK-453 是一种有效的非黄嘌呤腺苷 A1 受体拮抗剂，具有利尿和肾血管扩张活性。
T1230	Pamabrom 巴马溴,帕马溴	Others	Others
	Pamabrom 是一种利尿剂，有效成分为8-bromotheophylline，能够缓解月经相关症状。
T25354L1	(Abs)-DuP 747-HCl	Others	Others
	(Abs)-DuP 747-HCl 具有镇痛活性，可作为利尿剂使用。
T6835	Fenoldopam mesylate Fenoldopam methanesulfonate,SKF-82526 mesylate,Corlopam mesylate,mesylate,SKF 82526,非诺多泮甲磺酸盐	Dopamine Receptor	GPCR/G Protein; Neuroscience
	Fenoldopam mesylate (Corlopam mesylate) 是一种多巴胺受体D1选择性激动剂。
T71664	Mespirenone	Others	Others
	Mespirenone 是一种具有利尿作用的螺内酯衍生物和醛固酮拮抗剂。
T31777	Fenquizone M.G. 13054	Others	Others
	Fenquizone (M.G. 13054) 是一种噻嗪样利尿剂，具有慢性抗高血压作用。Fenquizone 可用于水肿和高血压的研究。
T0435	Sulfinpyrazone (+/-)-Sulfinpyrazone,G-28315,苯磺保泰松,NSC 75925	COX	Immunology/Inflammation; Neuroscience
	Sulfinpyrazone (NSC-75925) 是一种口服有效的尿酸剂，具有抗血栓和血小板抑制作用。它可作用于慢性和间歇性痛风性关节炎。
T0126	Diazoxide 氯甲苯噻嗪,二氮嗪,SRG-95213,Sch-6783,Proglycem	ATPase; Potassium Channel; Autophagy	Autophagy; Membrane transporter/Ion channel
	Diazoxide (Proglycem) 是一种 ATP 敏感性的钾离子通道激活剂，是一种苯并噻二嗪衍生物，是一种用于高血压急症的外周血管扩张剂。
T60351	Acetazolamide sodium OT-302 sodium	Carbonic Anhydrase	Metabolism
	Acetazolamide sodium (OT-302 sodium) 是一种高效的碳酸酐酶 (CA)IX抑制剂，具有利尿、抗淋球菌和降压活性，可用于癫痫、青光眼、水肿和高原反应等适应症。
T2322	Fimasartan 非马沙坦,BR-A-657,Kanarb	Apoptosis; RAAS	Apoptosis; Endocrinology/Hormones
	Fimasartan (BR-A-657) 是血管紧张素受体 AT1 非肽类拮抗剂，用于研究高血压和心力衰竭。
T8634	8-Bromotheophylline Bromotheophylline,8-溴茶碱	Others	Others
	8-Bromotheophylline (Bromotheophylline) 是 Pamabrom 的活性部分，用于 Oxazolo[2,3-f]purinediones 的合成。Oxazolo[2,3-f]purinediones 可用于腺苷 A1和 A2A 受体上的亲和力评估。
T0106	Methazolamide L584601,醋甲唑胺,CL 8490	Carbonic Anhydrase	Metabolism
	Methazolamide (CL 8490) 是一种磺胺衍生物，用作碳酸酐酶 (carbonic anhydrase) 抑制剂，对人 carbonic anhydrase II 的 Ki=为 14 nM。它是降低眼压的药物，能够抑制由青光眼及其他眼病引起的眼压升高的作用。
T1449	Hydrochlorothiazide HCTZ,双氢氯噻嗪,氢氯噻嗪	Potassium Channel; Carbonic Anhydrase; TGF-beta/Smad	Membrane transporter/Ion channel; Metabolism; Stem Cells
	Hydrochlorothiazide (HCTZ) 是一种口服有效的噻嗪类的利尿药，可抑制转化 TGF-β/Smad 信号通路。它通过打开钙激活钾 (KCA) 通道发挥直接的血管松弛作用。它改善心脏功能，减少纤维化并具有降压作用。
T60561	Disulfamide	Carbonic Anhydrase	Metabolism
	Disulfamide 是一种具有口服活性的碳酸酐酶 (carbonic anhydrase) 抑制剂，其 IC50 值为 0.07 μM。Disulfamide 具有利尿作用，可通过抑制碳酸酐酶，阻止钠、碳酸氢盐在近曲小管中的重吸收，从而发挥作用。
T0083	Eplerenone Epoxymexrenone,CGP 30083,依普利酮,SC-66110	Glucocorticoid Receptor	Endocrinology/Hormones
	Eplerenone (CGP 30083) 是一种竞争性的、选择性的、具有口服活性的醛固酮 (aldosterone) 拮抗剂，IC50=138 nM。它对孕酮，雄激素，雌激素和糖皮质激素受体的亲和力低，可用于研究高血压和心肌梗死后的心力衰竭。
T68166L	Traxanox TFA Traxanox TFA(58712-69-9 Free base)	Others	Others
	Traxanox TFA 是一种可口服的利尿剂。Traxanox TFA 在体外增强小鼠腹膜巨噬细胞或大鼠腹膜多形核白细胞对酵母颗粒的吞噬作用。Traxanox TFA 对抑制BALB/c小鼠抗体产生的恢复作用。
T4564	Ethacrynic acid Edecrin,利尿酸,Etacrynic Acid,Hydromedin	Others; Calcium Channel; NF-κB; GST	Membrane transporter/Ion channel; Metabolism; NF-κB; Others; oxidation-reduction
	Ethacrynic acid (Edecrin) 是谷胱甘肽 S-转移酶抑制剂，也是NF-κB 信号传导途径的有效抑制剂，并且还调节白三烯的形成。它还可抑制 L 型电压依赖性和储存操作的钙通道，从而导致气道平滑肌细胞松弛。它是利尿剂，具有抗炎特性，可减轻类维生素 A 诱导的小鼠耳部水肿。
T35336	Furosemide sodium Frusemide Sodium,Lasix	Na-K-Cl cotransporter	Membrane transporter/Ion channel
	Furosemide sodium (Frusemide Sodium) 是 Na+/K+/2Cl- (NKCC)，NKCC1 和 NKCC2 共转运蛋白的有效的和具有口服活性抑制剂。Furosemide sodium 也是 GABAA 受体拮抗剂，对含 α6 受体的选择性是含 α1 受体的 100 倍。Furosemide sodium 用作利尿试剂，用于充血性心力衰竭，高血压和水肿的研究。
T0782	Benzthiazide Aquatag,苄噻嗪,Lemazide,Dihydrex	Carbonic Anhydrase	Metabolism
	Benzthiazide (Lemazide) 是长效利尿剂及抗高血压剂。它也是碳酸酐酶 9 的抑制剂，他对 CA9，CA2 和 CA1 的 Ki 分别为 8.0，8.8 和 10 nM。它对肿瘤细胞增殖具有抑制作用。
T22660	Chlorothiazide Sodium	Others	Others
	diuretic and antihypertensive
T19430	Indacrinone MK-196,Indacrynic acid,茚达立酮	Others	Others
	Indacrinone is an investigational diuretic.
T29510	A-49816 hydrochloride A-49816 HCl	Others	Others
	A-49816 hydrochloride is a diuretic.
T21416	Hydroflumethiazide Diurometon,Glomerulin,Diuredemina,Flutizide,Hidroflumetiazid	Others	Others
	Hydroflumethiazide is a thiazide diuretic. It has also shown the activity of anti-hypertensive.
T26214	SQ 28853 SQ-28853,SQ28853	Others	Others
	SQ 28853 is an inhibitor of ACE with diuretic properties.
T34955	Tripamide	Others	Others
	Tripamide is a type of diuretic.
T29498	A 56234 A56234,A-56234	Others	Others
	A 56234 is a high-ceiling diuretic.
T31419	Diapamide CN-36337,D-1593,CN-36,337,D 1593	Others	Others
	Diapamide is a new diuretic and antihypertensive agent.
T34469	S 8666 S8666	Others	Others
	S 8666 is a potent diuretic with uricosuric action.
T24669	Protheobromine Pro-Cor,Theocor,Protheobrominum,TEBE,Vascopil	Others	Others
	Protheobromine is a diuretic drug.
T30043	Ampyrimine	Others	Others
	Ampyrimine is a Diuretic.
T28872	SU 15049A SU15049A,SU-15049A	Others	Others
	SU 15049A is a diuretic agent.
T29985	Aminometradine Catapyrin,Aminometramide,BRN 0175533	Others	Others
	Aminometradine is a diuretic agent.
T29496	A 49816 A49816,A-49816	Others	Others
	A 49816 is a high-ceiling diuretic.
T33297	Mersalyl Diursal,Salyrgan,Igrosin,Salurin,Mercuramide	Others	Others
	Mersalyl is an organic mercurial diuretic.
T30973	Clofenamide Aponiere,Haflutan,Frictan,Eleklin,Indigatin	Others	Others
	Clofenamide is a low-ceiling sulfonamide diuretic.
T19646	Altizide CB-8093,Aldactacine,P 1779,CB 8093,P1779,P-1779	Others	Others
	Altizide is a thiazide diuretic. It is used to treat oedema and hypertension.
T26565	Adentri BG-9719,BG9719,BG 9719,CVT124,CVT-124,CVT 124	Others	Others
	Adentri is a novel antagonist of adenosine A1 receptor with unique diuretic activity.

化合物

Potassium acetate

Cat.No: T8129

Synonym: Diuretic salt,Potassium ethanoate,乙酸钾

Target: Antifungal

Cat.No: T10441

Target: Na-K-Cl cotransporter

Cyclopenthiazide

Cat.No: T21469

Synonym: Cyclomethiazide,Su-8341,SU 8341,环戊噻嗪

Target: Others

Cat.No: T36125

Target: P450

Trichlormethiazide

Cat.No: T0114

Synonym: Naqua,Metahydrin,三氯噻嗪,Trichlormetazid

Target: ATPase, Carbonic Anhydrase

Cat.No: T6086

Synonym: Brinaldix,Adurix,Aquex,氯帕胺

Target: Sodium Channel

Cat.No: T1410

Synonym: AC-4464,JDL-464,托拉塞米,Torasemide

Target: Na-K-Cl cotransporter

Cat.No: T6288

Synonym: 莫扎伐坦,OPC31260l,OPC-31260

Target: Vasopressin Receptor

Cat.No: T6551

Synonym: Devicoran,Isobide,异山梨酯,异山梨醇,Hydronol,Dianhydro-D-glucitol,D-Isosorbide

Target: Others

Canrenoate potassium

Cat.No: T3096

Synonym: 坎利酸钾,Potassium aldadiene,Canrenoic acid potassium salt,Potassium canrenoate,Soldactone

Target: Glucocorticoid Receptor

Cat.No: T17266

Synonym: 希伯胺,Diurexan,Aquaphor

Target: Others

Cat.No: T0275

Synonym: 美替克仑,Fontiliz,Arresten,蒲硫杂茶磺胺

Target: Chloride channel, Sodium Channel

Leucokinin VIII acetate

Cat.No: TP1114L

Synonym: Leucokinin 8

Target: Others

Cat.No: T27323

Synonym: FK453,FK 453

Target: Adenosine Receptor

Cat.No: T1230

Synonym: 巴马溴,帕马溴

Target: Others

(Abs)-DuP 747-HCl

Cat.No: T25354L1

Target: Others

Fenoldopam mesylate

Cat.No: T6835

Synonym: Fenoldopam methanesulfonate,SKF-82526 mesylate,Corlopam mesylate,mesylate,SKF 82526,非诺多泮甲磺酸盐

Target: Dopamine Receptor

Cat.No: T71664

Target: Others

Cat.No: T31777

Synonym: M.G. 13054

Target: Others

Cat.No: T0435

Synonym: (+/-)-Sulfinpyrazone,G-28315,苯磺保泰松,NSC 75925

Target: COX

Cat.No: T0126

Synonym: 氯甲苯噻嗪,二氮嗪,SRG-95213,Sch-6783,Proglycem

Target: ATPase, Potassium Channel, Autophagy

Acetazolamide sodium

Cat.No: T60351

Synonym: OT-302 sodium

Target: Carbonic Anhydrase

Cat.No: T2322

Synonym: 非马沙坦,BR-A-657,Kanarb

Target: Apoptosis, RAAS

8-Bromotheophylline

Cat.No: T8634

Synonym: Bromotheophylline,8-溴茶碱

Target: Others

Cat.No: T0106

Synonym: L584601,醋甲唑胺,CL 8490

Target: Carbonic Anhydrase

Hydrochlorothiazide

Cat.No: T1449

Synonym: HCTZ,双氢氯噻嗪,氢氯噻嗪

Target: Potassium Channel, Carbonic Anhydrase, TGF-beta/Smad

Cat.No: T60561

Target: Carbonic Anhydrase

Cat.No: T0083

Synonym: Epoxymexrenone,CGP 30083,依普利酮,SC-66110

Target: Glucocorticoid Receptor

Cat.No: T68166L

Synonym: Traxanox TFA(58712-69-9 Free base)

Target: Others

Ethacrynic acid

Cat.No: T4564

Synonym: Edecrin,利尿酸,Etacrynic Acid,Hydromedin

Target: Others, Calcium Channel, NF-κB, GST

Furosemide sodium

Cat.No: T35336

Synonym: Frusemide Sodium,Lasix

Target: Na-K-Cl cotransporter

Cat.No: T0782

Synonym: Aquatag,苄噻嗪,Lemazide,Dihydrex

Target: Carbonic Anhydrase

Chlorothiazide Sodium

Cat.No: T22660

Target: Others

Cat.No: T19430

Synonym: MK-196,Indacrynic acid,茚达立酮

Target: Others

A-49816 hydrochloride

Cat.No: T29510

Synonym: A-49816 HCl

Target: Others

Hydroflumethiazide

Cat.No: T21416

Synonym: Diurometon,Glomerulin,Diuredemina,Flutizide,Hidroflumetiazid

Target: Others

Cat.No: T26214

Synonym: SQ-28853,SQ28853

Target: Others

Cat.No: T34955

Target: Others

Cat.No: T29498

Synonym: A56234,A-56234

Target: Others

Cat.No: T31419

Synonym: CN-36337,D-1593,CN-36,337,D 1593

Target: Others

Cat.No: T34469

Synonym: S8666

Target: Others

Cat.No: T24669

Synonym: Pro-Cor,Theocor,Protheobrominum,TEBE,Vascopil

Target: Others

Cat.No: T30043

Target: Others

Cat.No: T28872

Synonym: SU15049A,SU-15049A

Target: Others

Cat.No: T29985

Synonym: Catapyrin,Aminometramide,BRN 0175533

Target: Others

Cat.No: T29496

Synonym: A49816,A-49816

Target: Others

Cat.No: T33297

Synonym: Diursal,Salyrgan,Igrosin,Salurin,Mercuramide

Target: Others

Cat.No: T30973

Synonym: Aponiere,Haflutan,Frictan,Eleklin,Indigatin

Target: Others

Cat.No: T19646

Synonym: CB-8093,Aldactacine,P 1779,CB 8093,P1779,P-1779

Target: Others

Cat.No: T26565

Synonym: BG-9719,BG9719,BG 9719,CVT124,CVT-124,CVT 124

Target: Others

Cat. No.	Product Name	Target	Signaling Pathways
T2780	Catalpol 梓醇,Catalpinoside,Digitalis purpurea L	Others; HBV	Microbiology/Virology; Others
	Catalpol (Catalpinoside) 是一种在Rehmannia glutinosa 中发现的鸢尾花苷，具有神经保护、降血糖、抗癌、抗痉挛、抗氧化、抗HBV 和抗肝炎病毒作用。
T0354	Canrenone 6,7-Dehydro-7α-desthioacetylspironolactone,SC9376,Aldadiene,坎利酮,RP-11614,SC14266	Glucocorticoid Receptor; Endogenous Metabolite	Endocrinology/Hormones; Metabolism
	Canrenone (SC14266) 是一种醛固酮 (aldosterone) 拮抗剂，广泛用作利尿剂。
T4959	DL-Mannitol 甘露醇,Mannitol	Others	Others
	DL-Mannitol 是由 D-mannitol 与 L-mannitol 通过 L-mannono-1, Clactone 还原得到的。
T6S2238	Eupalinolide B	Others	Others
	Eupalinolide B 是一种胚芽倍半萜，分离自Eupatorium lindleyanum 中。它对BGC-823、A-549 和 HL-60 等肿瘤细胞具有细胞毒性。
T2S0265	Robinin NSC 9222,刺槐素	TLR	Immunology/Inflammation
	Flavone glycoside from Robinia with antibacterial and diuretic properties; derived from kaempferol.The ability of robinin to reverse the multidrug resistance of the human colon cancer cell line Colo 320 expreβing MDR1/LRP was explored by monitoring their uptake of Rhodamine 123, but was shown to have minimal effect. Robinin (NSC-9222) was detected in lysates of the human breast cancer cell line MCF-7 using liquid chromatography-tandem maβ spectrometry.
T0332	D-Sorbitol 山梨醇,Glucitol,Sorbitol,D-Glucitol	Others; Endogenous Metabolite	Metabolism; Others
	D-Sorbitol (Sorbitol) 是一种六碳糖醇，能够用作糖的替代品。D-Sorbitol 能够用作稳定的赋形剂和/或等渗剂，保湿剂，增稠剂，甜味剂和膳食补充剂。
T1083	Theophylline Theo-24,1,3-Dimethylxanthine,茶碱	Endogenous Metabolite; HDAC; PDE; Adenosine Receptor; Autophagy	Autophagy; Chromatin/Epigenetic; DNA Damage/DNA Repair; GPCR/G Protein; Metabolism; Neuroscience
	Theophylline (1,3-Dimethylxanthine) 是茶中的甲基黄嘌呤衍生物，具有利尿、平滑肌松弛、支气管扩张、心脏和中枢神经系统兴奋作用。
T0892	Diphylline 二羟丙茶碱,Dyphylline,Diprophylline	PDE; Adenosine Receptor	GPCR/G Protein; Metabolism; Neuroscience
	Diphylline (Diprophylline) 是一种A1/A2腺苷受体拮抗剂，也是环状核苷酸磷酸二酯酶抑制剂。它是一种黄嘌呤衍生物，具有支气管扩张和血管扩张作用，有用于治疗慢性支气管炎和肺气肿的潜力。
T0414	D-Mannitol Mannite,Mannitol,D-甘露糖醇,Osmitrol	Apoptosis; Dehydrogenase; Endogenous Metabolite	Apoptosis; Metabolism
	D-Mannitol (Mannitol) 是与山梨醇相关的利尿剂和肾脏诊断辅助剂，具有较弱的肾脏血管扩张活性。
TN7323	Oxyphyllol B	Others	Others
	Oxyphyllol B exhibits pronounced diuretic and antidiuretic properties.
TN4967	Scoparinol
	Scoparinol has sedative, anti-inflammatory, analgesic, and diuretic actions.
T83522	(S)-(+)-Imperanene
	(S)-(+)-Imperanene 是从 Imperata cylindrica 中分离得到的化合物，后者具有明显的利尿和抗炎作用。
T80019	17-Hydroxyneomatrine	Others	Others
	17-Hydroxyneomatrine 是一种从苦参 (Sophora flavescens) 提取的化合物，有效抑制人宫颈癌Hela细胞生长，并展现抗菌、抗过敏、抗肿瘤、抗心律失常、消肿、利尿、免疫调节等多种生物活性。
TN1681	Gentianine	Others; TNF; transporter; PPAR	Apoptosis; DNA Damage/DNA Repair; Metabolism; Others
	Gentianine 是一种有效的 Swertiamarin 衍生物，具有抗糖尿病、抗精神病、抗炎、降血压、利尿等作用，具有被开发成一种安全的降压药物的潜力。
T81117	Spilanthol
	Spilanthol为一具有多种生物活性的化合物，包括镇痛、神经保护、抗氧化、抗诱变、抗癌、抗炎、抗菌以及杀虫作用。该化合物能够通过诱导cAMP抑制尿浓缩的负调节机制，且可作为利尿剂研究的候选物。
TN7330	β-Cedrene (+)-β-Cedrene	Others	Others
	β-Cedrene ((+)-β-Cedrene)，一种从Centaurea kotschyi var.kotschyi与Centaurea kotschyi var. decumbens分离的倍半萜烯化合物，展现出抗菌、抗炎、抗痉挛、滋补、收敛、利尿、镇静、杀虫及抗真菌活性。同时，β-Cedrene 是CYP2B6介导的安非他酮羟化酶的强效竞争性抑制剂，具有1.6 μM的Ki值。

天然产物

Cat.No: T2780

Synonym: 梓醇,Catalpinoside,Digitalis purpurea L

Target: Others, HBV

Cat.No: T0354

Synonym: 6,7-Dehydro-7α-desthioacetylspironolactone,SC9376,Aldadiene,坎利酮,RP-11614,SC14266

Target: Glucocorticoid Receptor, Endogenous Metabolite

Cat.No: T4959

Synonym: 甘露醇,Mannitol

Target: Others

Cat.No: T6S2238

Target: Others

Cat.No: T2S0265

Synonym: NSC 9222,刺槐素

Target: TLR

Cat.No: T0332

Synonym: 山梨醇,Glucitol,Sorbitol,D-Glucitol

Target: Others, Endogenous Metabolite

Cat.No: T1083

Synonym: Theo-24,1,3-Dimethylxanthine,茶碱

Target: Endogenous Metabolite, HDAC, PDE, Adenosine Receptor, Autophagy

Cat.No: T0892

Synonym: 二羟丙茶碱,Dyphylline,Diprophylline

Target: PDE, Adenosine Receptor

Cat.No: T0414

Synonym: Mannite,Mannitol,D-甘露糖醇,Osmitrol

Target: Apoptosis, Dehydrogenase, Endogenous Metabolite

Cat.No: TN7323

Target: Others

Cat.No: TN4967

(S)-(+)-Imperanene

Cat.No: T83522

17-Hydroxyneomatrine

Cat.No: T80019

Target: Others

Cat.No: TN1681

Target: Others, TNF, transporter, PPAR

Cat.No: T81117

Cat.No: TN7330

Synonym: (+)-β-Cedrene

Target: Others

Species：

Expression System：

Tag：

Cat. No.	Product Name	Species	Expression System
TMPY-02839	Adrenomedullin Protein, Human, Recombinant (hFc) AM,PAMP,adrenomedullin	Human	HEK293 Cells
	Adrenomedullin consists of 52 amino acids and is a member of the adrenomedullin family. It s a a hypotensive peptide and has 1 intramolecular disulfide bond. It seems that adrenomedullin has a slight homology with the calcitonin gene-related peptide. Adrenomedullin has a highly expression in pheochromocytoma and adrenal medulla. It also can be detected in lung, ventricle and kidney tissues. Adrenomedullin and PAMP are potent hypotensive and vasodilatator agents. Numerous actions have been report...

重组蛋白

Adrenomedullin Protein, Human, Recombinant (hFc)

Cat.No: TMPY-02839

Species: Human

Expression System: HEK293 Cells

Cat. No.	Product Name	Target	Signaling Pathways
T19591	Triamterene D5 氨苯蝶啶 D5	Others	Others
	Triamterene D5 is a deuterium-labeled Triamterene and can block epithelial Na+ channel (ENaC) in a voltage-dependent manner, used as a mild diuretic.
TMID-0125	Canrenone-d4
	Canrenone-d4 是 Canrenone 的氘代化合物。Canrenone 的 CAS 号为 976-71-6。Canrenone 是一种醛固酮 (aldosterone) 拮抗剂，广泛用作利尿剂。
TMIH-0342	Metolazone-d7
	Metolazone-d7 是 Metolazone 的氘代化合物。Metolazone 的 CAS 号为 17560-51-9。Metolazone 具有抗心力衰竭和高血压作用。
TMID-0124	Canrenone-d6
	Canrenone-d6 是 Canrenone 的氘代化合物。Canrenone 的 CAS 号为 976-71-6。Canrenone 是一种醛固酮 (aldosterone) 拮抗剂，广泛用作利尿剂。
TMID-0228	Chlorthalidone-d4
	Chlorthalidone-d4 是 Chlorthalidone 的氘代化合物。Chlorthalidone 的 CAS 号为 77-36-1。Chlorthalidone 是噻嗪类利尿剂，有用于高血压的研究潜力。
T11240	Ethacrynic acid D5	Others	Others
	Ethacrynic acid, a diuretic, functions as an inhibitor of L-type voltage-dependent and store-operated calcium channels, facilitating the relaxation of airway smooth muscle (ASM) cells. It exhibits anti-inflammatory effects, notably reducing retinoid-induced ear edema in mice, and inhibits glutathione S-transferases (GSTs), making it a potent suppressor of the NF-kB signaling pathway. Additionally, ethacrynic acid modulates leukotriene formation. A variant, Ethacrynic acid D5, is distinguished by...
TMID-0238	Hydrochlorothiazid-d2
	Hydrochlorothiazid-d2 是 Hydrochlorothiazid 的氘代化合物。Hydrochlorothiazid 的 CAS 号为 58-93-5。Hydrochlorothiazide 是一种口服有效的噻嗪类的利尿药，可抑制转化TGF-β/Smad信号通路。它通过打开钙激活钾 (KCA) 通道发挥直接的血管松弛作用。它改善心脏功能，减少纤维化并具有降压作用。
TMID-0063	rac Bendroflumethiazide-d5
	rac Bendroflumethiazide-d5 是 rac Bendroflumethiazide 的氘代化合物。rac Bendroflumethiazide 的 CAS 号为 73-48-3。Bendroflumethiazide 是一种口服具有活性的利尿剂。它是一种抗高血压药。它对动脉高血压疾病具有潜在的研究价值。
TMID-0119	Diprophylline-d6
	Diprophylline-d6 是 Diprophylline 的氘代化合物。Diprophylline 的 CAS 号为 479-18-5。Diphylline 是一种A1/A2腺苷受体拮抗剂，也是环状核苷酸磷酸二酯酶抑制剂。它是一种黄嘌呤衍生物，具有支气管扩张和血管扩张作用，有用于治疗慢性支气管炎和肺气肿的潜力。

同位素标记化合物

Cat.No: T19591

Synonym: 氨苯蝶啶 D5

Target: Others

Cat.No: TMID-0125

Cat.No: TMIH-0342

Cat.No: TMID-0124

Chlorthalidone-d4

Cat.No: TMID-0228

Ethacrynic acid D5

Cat.No: T11240

Target: Others

Hydrochlorothiazid-d2

Cat.No: TMID-0238

rac Bendroflumethiazide-d5

Cat.No: TMID-0063

Diprophylline-d6

Cat.No: TMID-0119

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