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Search Results for " deacetylate "

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Cat. No.	Product Name	Target	Signaling Pathways
T13996	1-Naphthohydroxamic acid	HDAC	Chromatin/Epigenetic; DNA Damage/DNA Repair
	1-Naphthohydroxamic acid 是一种选择性 HDAC8抑制剂，IC50为 14 μM。它对 HDAC8的选择性高于 I 类 HDAC1 和 II 类 HDAC6，IC50大于100 μM，可诱导微管蛋白乙酰化。
T12143	N-deacetylated BMS-202	Others	Others
	N-deacetylated BMS-202 is the deacetylated of BMS-202.
T70748	Bisthianostat	Others	Others
	Bisthianostat, also known as CF367 or CF367;-C, is a novel Orally Efficacious Pan-HDAC Inhibitor. Bisthianostat selectively binds to and inhibits HDACs, which inhibits deacetylation of histone proteins and leads to the accumulation of highly acetylated histones. This may result in an induction of chromatin remodeling, the inhibition of tumor oncogene transcription, and the selective transcription of tumor suppressor genes. This prevents cell division, induces cell cycle arrest and apoptosis. Thi...