|
TMPH-02619
|
CKAP4 Protein, Mouse, Recombinant (His & Myc)
Climp-63,Cytoskeleton-associated protein 4,Ckap4,p6...
|
Mouse
|
E. coli
|
|
High-affinity epithelial cell surface receptor for APF.; Mediates the anchoring of the endoplasmic reticulum to microtubules. CKAP4 Protein, Mouse, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 57.6 kDa and the accession number is Q8BMK4. |
|
TMPH-02620
|
CKAP4 Protein, Mouse, Recombinant (His & MBP)
Ckap4,p63,Climp-63,63-kDa cytoskeleton-linking memb...
|
Mouse
|
Baculovirus Insect Cells
|
|
High-affinity epithelial cell surface receptor for APF.; Mediates the anchoring of the endoplasmic reticulum to microtubules. CKAP4 Protein, Mouse, Recombinant (His & MBP) is expressed in Baculovirus insect cells with N-MBP and C-6xHis tag. The predicted molecular weight is 96.6 kDa and the accession number is Q8BMK4. |
|
TMPH-02282
|
Ubiquilin-1 Protein, Human, Recombinant (His & Myc)
Ubiquilin-1,UBQLN1,Protein linking IAP with cytoskeleton...
|
Human
|
E. coli
|
|
Plays an important role in the regulation of different protein degradation mechanisms and pathways including ubiquitin-proteasome system (UPS), autophagy and endoplasmic reticulum-associated protein degradation (ERAD) pathway. Mediates the proteasomal targeting of misfolded or accumulated proteins for degradation by binding (via UBA domain) to their polyubiquitin chains and by interacting (via ubiquitin-like domain) with the subunits of the proteasome. Plays a role in the ERAD pathway via its in... |
|
TMPY-02953
|
TEM8/ANTXR1 Protein, Human, Recombinant (hFc)
ATR,TEM8,anthrax toxin receptor 1,GAPO
|
Human
|
HEK293 Cells
|
|
ANTXR1 contains 1 VWFA domain and belongs to the ATR family. ATR (Ataxia telangiectasia and Rad3 related) and ATM (Ataxia telangiectasia mutated) are closely related kinases that are activated by DNA damage. They are serine-threonine protein kinases and belongs to the phosphatidylinositol 3' kinase-like kinase (PIKK) family. Upon recruitment by the DNA damage binding proteins/complexes (ATRIP for ATR; MRN for ATM), ATM/ATR initiate the DNA damage checkpoint by phosphorylating a number of key pro... |
|
TMPH-00010
|
MMP-14 Protein, Human, Recombinant (His & SUMO)
Membrane-type-1 matrix metalloproteinase,MMP14,Membrane-type...
|
Human
|
E. coli
|
|
Endopeptidase that degrades various components of the extracellular matrix such as collagen. Activates progelatinase A. Essential for pericellular collagenolysis and modeling of skeletal and extraskeletal connective tissues during development. May be involved in actin cytoskeleton reorganization by cleaving PTK7. Acts as a positive regulator of cell growth and migration via activation of MMP15. Involved in the formation of the fibrovascular tissues in association with pro-MMP2. Cleaves ADGRB1 to... |
|
TMPY-04396
|
C-ABL/ABL1 Protein, Human, Recombinant (GST)
v-abl,ABL,JTK7,ABL proto-oncogene 1, non-receptor tyrosine k...
|
Human
|
Baculovirus Insect Cells
|
|
c-Abl belongs to the class of tyrosine kinases and is the prototype of a subfamily which includes two members, c-Abl and Arg (Abl-related gene). Both proteins are localized at the cell membrane, actin cytoskeleton and cytosol, and c-Abl is present in the nucleus as well. c-Abl is a non-receptor tyrosine kinase that participates in multiple signaling pathways linking the cell surface, cytoskeleton, and the nucleus. Recent in vitro studies have also linked c-Abl to amyloid-beta-induced toxicity an... |
|
TMPY-05717
|
Integrin alpha V beta 8 Protein, Human, Recombinant (His)
Integrin alpha V β8,Integrin α V β 8
|
Human
|
HEK293 Cells
|
|
Integrin alpha V beta 8 is a receptor for fibronectin. It recognizes the sequence R-G-D in its ligands. ITGAVB8 does not appear to assume different activation states; and the cytoplasmic tail does not connect to the cytoskeleton. It binds ligands containing an RGD motif; including vitronectin; fibrin and the latency associated peptide (LAP) of the latent TGF-beta complex. High affinity binding of alpha V beta 8 to LAP allows proteolytic cleavage by MT1-MMP; which releases active TGF-beta. This m... |
|
TMPJ-00327
|
M-CSF/CSF1 Protein, Human, Recombinant (His)
Lanimostim,M-CSF,CSF-1,MCSF,CSF1,集落刺激因子,Macrophage Colony-St...
|
Human
|
HEK293 Cells
|
|
Macrophage Colony-Stimulating Factors (m-csf) are cytokines that act in hematopoiesis by controlling the production, differentiation, and function of 2 related white cell populations of the blood, the granulocytes and themonocytes-macrophages. CSF-1 promotes the release of proinflammatory chemokines, and thereby plays an important role in innate immunity and in inflammatory processes. It also plays an important role in the regulation of osteoclast proliferation and differentiation, the regulatio... |
|
TMPH-02512
|
TEM8/ANTXR1 Protein, Mouse, Recombinant (His)
Tumor endothelial marker 8,Anthrax toxin receptor 1,Antxr1
|
Mouse
|
E. coli
|
|
Plays a role in cell attachment and migration. Interacts with extracellular matrix proteins and with the actin cytoskeleton. Mediates adhesion of cells to type 1 collagen and gelatin, reorganization of the actin cytoskeleton and promotes cell spreading. Plays a role in the angiogenic response of cultured umbilical vein endothelial cells. |
|
TMPH-02513
|
TEM8/ANTXR1 Protein, Mouse, Recombinant (His & Myc)
Antxr1,Tumor endothelial marker 8,Anthrax toxin receptor 1
|
Mouse
|
HEK293 Cells
|
|
Plays a role in cell attachment and migration. Interacts with extracellular matrix proteins and with the actin cytoskeleton. Mediates adhesion of cells to type 1 collagen and gelatin, reorganization of the actin cytoskeleton and promotes cell spreading. Plays a role in the angiogenic response of cultured umbilical vein endothelial cells. |
|
TMPH-03027
|
HMW1 Protein, Mycoplasma pneumoniae, Recombinant (His & Myc)
Cytadherence accessory protein 1,Cytadherence high molecular...
|
Mycoplasma pneumoniae
|
E. coli
|
|
Component of the cytoskeleton-like structure which stabilizes the shape of the wall-less Mycoplasma. This cytoskeleton-like network of accessory proteins containing HMW proteins 1 to 5 allows the proper anchoring of cytadhesin proteins in the mycoplasmal membrane at the attachment organelle. |
|
TMPH-03033
|
P200 Protein, Mycoplasma pneumoniae, Recombinant (His & Myc)
p200,Protein P200
|
Mycoplasma pneumoniae
|
E. coli
|
|
Protein cytoskeleton-associated which plays a role in gliding motility and perhaps also in mucociliary clearance. |
|
TMPH-03028
|
HMW3 Protein, Mycoplasma pneumoniae, Recombinant (His & Myc)
hmw3,Accessory adhesin protein 3,Cytadherence accessory prot...
|
Mycoplasma pneumoniae
|
E. coli
|
|
Component of the cytoskeleton-like structure which stabilizes the shape of the wall-less mycoplasma. This cytoskeleton-like network of accessory proteins containing HMW proteins 1 to 5 allows the proper anchoring of cytadhesin proteins in the mycoplasmal membrane at the attachment organelle. Essential for successful surface parasitism. HMW3 Protein, Mycoplasma pneumoniae, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight... |
|
TMPH-01228
|
DPYSL3 Protein, Human, Recombinant (His)
ULIP-1,DRP-3,Dihydropyrimidinase-related protein 3,DPYSL3,Un...
|
Human
|
E. coli
|
|
Necessary for signaling by class 3 semaphorins and subsequent remodeling of the cytoskeleton. Plays a role in axon guidance, neuronal growth cone collapse and cell migration. |
|
TMPH-01226
|
CRMP1 Protein, Human, Recombinant
ULIP3,Collapsin response mediator protein 1,CRMP1,Dihydropyr...
|
Human
|
E. coli
|
|
Necessary for signaling by class 3 semaphorins and subsequent remodeling of the cytoskeleton. Plays a role in axon guidance. During the axon guidance process, acts downstream of SEMA3A to promote FLNA dissociation from F-actin which results in the rearrangement of the actin cytoskeleton and the collapse of the growth cone. Involved in invasive growth and cell migration. May participate in cytokinesis. CRMP1 Protein, Human, Recombinant is expressed in E. coli expression system. The predicted mole... |
|
TMPH-01704
|
RAE1 Protein, Human, Recombinant (GST)
Rae1 protein homolog,mRNA-associated protein mrnp 41,mRNA ex...
|
Human
|
E. coli
|
|
Plays a role in mitotic bipolar spindle formation. Binds mRNA. May function in nucleocytoplasmic transport and in directly or indirectly attaching cytoplasmic mRNPs to the cytoskeleton. RAE1 Protein, Human, Recombinant (GST) is expressed in E. coli expression system with N-GST tag. The predicted molecular weight is 68.0 kDa and the accession number is P78406. |
|
TMPH-01227
|
DPYSL2 Protein, Human, Recombinant (His)
Dihydropyrimidinase-related protein 2,Collapsin response med...
|
Human
|
P. pastoris (Yeast)
|
|
Plays a role in neuronal development and polarity, as well as in axon growth and guidance, neuronal growth cone collapse and cell migration. Necessary for signaling by class 3 semaphorins and subsequent remodeling of the cytoskeleton. May play a role in endocytosis. |
|
TMPH-02130
|
SPTAN1 Protein, Human, Recombinant (His & SUMO)
Fodrin alpha chain,Spectrin alpha chain, non-erythrocytic 1,...
|
Human
|
E. coli
|
|
Fodrin, which seems to be involved in secretion, interacts with calmodulin in a calcium-dependent manner and is thus candidate for the calcium-dependent movement of the cytoskeleton at the membrane. |
|
TMPY-03600
|
TPM4 Protein, Human, Recombinant (His)
tropomyosin 4,HEL-S-108,TPM4
|
Human
|
HEK293 Cells
|
|
TPM4, also known as tropomyosin 4, is a member of the tropomyosin family. Members of this family are actin-binding proteins involved in the contractile system of striated and smooth muscles and the cytoskeleton of non-muscle cells. TPM4 is expressed in cardiac tissue and platelets. It is highly expressed in the platelets of hypertensive patients. TPM4 plays a central role, in association with the troponin complex, in the calcium-dependent regulation of vertebrate striated muscle contraction. Smo... |
|
TMPH-02161
|
Synapsin-1 Protein, Human, Recombinant (GST)
SYN1,Brain protein 4.1,Synapsin I,Synapsin-1
|
Human
|
E. coli
|
|
Neuronal phosphoprotein that coats synaptic vesicles, binds to the cytoskeleton, and is believed to function in the regulation of neurotransmitter release. The complex formed with NOS1 and CAPON proteins is necessary for specific nitric-oxid functions at a presynaptic level. |
|
TMPH-02202
|
TMSB10 Protein, Human, Recombinant (GST)
TMSB10,Thymosin beta-10
|
Human
|
E. coli
|
|
Plays an important role in the organization of the cytoskeleton. Binds to and sequesters actin monomers (G actin) and therefore inhibits actin polymerization. TMSB10 Protein, Human, Recombinant (GST) is expressed in E. coli expression system with N-GST tag. The predicted molecular weight is 31.6 kDa and the accession number is P63313. |
|
TMPH-02252
|
TPM3 Protein, Human, Recombinant (GST)
Gamma-tropomyosin,Tropomyosin alpha-3 chain,Tropomyosin-3,TP...
|
Human
|
E. coli
|
|
Binds to actin filaments in muscle and non-muscle cells. Plays a central role, in association with the troponin complex, in the calcium dependent regulation of vertebrate striated muscle contraction. Smooth muscle contraction is regulated by interaction with caldesmon. In non-muscle cells is implicated in stabilizing cytoskeleton actin filaments. |
|
TMPH-02935
|
TMSB10 Protein, Mouse, Recombinant (His & SUMO)
Thymosin beta-10,Tmsb10
|
Mouse
|
E. coli
|
|
Plays an important role in the organization of the cytoskeleton. Binds to and sequesters actin monomers (G actin) and therefore inhibits actin polymerization. TMSB10 Protein, Mouse, Recombinant (His & SUMO) is expressed in E. coli expression system with N-6xHis-SUMO tag. The predicted molecular weight is 17.8 kDa and the accession number is Q6ZWY8. |
|
TMPY-03984
|
TPM1 Protein, Human, Recombinant (His)
TMSA,tropomyosin 1 (alpha),LVNC9,CMH3,HTM-alpha,CMD1Y,C15orf...
|
Human
|
E. coli
|
|
TPM1, also known as tropomyosin-1, is a member of the tropomyosin family. Members of this family are highly conserved, widely distributed actin-binding proteins involved in the contractile system of striated and smooth muscles and the cytoskeleton of non-muscle cells. highly conserved, widely distributed actin-binding proteins involved in the contractile system of striated and smooth muscles and the cytoskeleton of non-muscle cells. TPM1 is one type of alpha-helical chain that forms the predomin... |
|
TMPJ-01333
|
TEM8/ANTXR1 Protein, Human, Recombinant (His)
ATR,ANTXR1,TEM8,Tumor Endothelial Marker 8,Anthrax Toxin Rec...
|
Human
|
HEK293 Cells
|
|
Anthrax Toxin Receptor 1 (ANTXR1) is a single-pass type I membrane protein that belongs to the ATR family. ANTXR1 contains one VWFA domain and binds PA through the VWA domain. ANTXR1 is highly expressed in tumor endothelial cells. ANTXR1 plays a role in cell attachment and migration. ANTXR1 interacts with extracellular matrix proteins and the actin cytoskeleton, it mediates adhesion of cells to type 1 collagen and gelatin, reorganization of the actin cytoskeleton and promotes cell spreading. It ... |
|
TMPK-00936
|
CKAP4 Protein, Human, Recombinant (His)
Climp-63,ERGIC-63,p63
|
Human
|
E. coli
|
|
Cytoskeleton-associated protein 4 (CKAP4) is located in the rough endoplasmic reticulum (ER) and plays an important role in stabilizing the structure of ER. Meanwhile, CKAP4 is also found to act as an activated receptor at the cell surface. CKAP4 Protein, Human, Recombinant (His) is expressed in E. coli expression system with N-His tag. The predicted molecular weight is 53.66 kDa and the accession number is Q07065. |
|
TMPH-03096
|
Profilin 2 Protein, Phleum pratense, Recombinant (His & Myc)
Pollen allergen Phl p 12,Allergen Phl p 11,Profilin 4,PRO4,P...
|
Phleum pratense
|
E. coli
|
|
Binds to actin and affects the structure of the cytoskeleton. At high concentrations, profilin prevents the polymerization of actin, whereas it enhances it at low concentrations. By binding to PIP2, it inhibits the formation of IP3 and DG. Profilin 2 Protein, Phleum pratense, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 21.5 kDa and the accession number is O24650. |
|
TMPJ-01188
|
CORO6 Protein, Human, Recombinant (His)
Coronin-6,Clipin-E,CORO6
|
Human
|
E. coli
|
|
Coronin 6, a newly identified member of the coronin family, is highly enriched at adult NMJs and regulates AChR clustering via modulating the interaction between receptors and the actin cytoskeletal network. Coronins are a family of conserved actin-binding proteins originally identified in the actin-rich structure of the amoeba Dictyostelium discoideum . To date, seven members of coronins have been identified in mammals, and most exhibit tissue-specific distribution patterns. Coronin 6 is promin... |
|
TMPK-00937
|
CKAP4 Protein (Primary Amine Labeling), Human, Recombinant (His), Biotinylated
p63,CLIMP-63,ERGIC-63
|
Human
|
E. coli
|
|
Cytoskeleton-associated protein 4 (CKAP4) is located in the rough endoplasmic reticulum (ER) and plays an important role in stabilizing the structure of ER. Meanwhile, CKAP4 is also found to act as an activated receptor at the cell surface. CKAP4 Protein (Primary Amine Labeling), Human, Recombinant (His), Biotinylated is expressed in E. coli expression system with N-His tag. The predicted molecular weight is 53.66 kDa and the accession number is Q07065. |
|
TMPH-01876
|
Plexin-B1 Protein, Human, Recombinant (mFc)
Plexin-B1,Semaphorin receptor SEP,PLXNB1
|
Human
|
HEK293 Cells
|
|
Receptor for SEMA4D. Plays a role in GABAergic synapse development. Mediates SEMA4A- and SEMA4D-dependent inhibitory synapse development. Plays a role in RHOA activation and subsequent changes of the actin cytoskeleton. Plays a role in axon guidance, invasive growth and cell migration. Plexin-B1 Protein, Human, Recombinant (mFc) is expressed in HEK293 mammalian cells with N-mFc tag. The predicted molecular weight is 83.2 kDa and the accession number is O43157. |
|
TMPH-02758
|
LIMS1 Protein, Mouse, Recombinant (His)
LIM and senescent cell antigen-like-containing domain protei...
|
Mouse
|
Baculovirus Insect Cells
|
|
Adapter protein in a cytoplasmic complex linking beta-integrins to the actin cytoskeleton, bridges the complex to cell surface receptor tyrosine kinases and growth factor receptors. Involved in the regulation of cell survival, cell proliferation and cell differentiation. LIMS1 Protein, Mouse, Recombinant (His) is expressed in Baculovirus insect cells with N-10xHis tag. The predicted molecular weight is 39.6 kDa and the accession number is Q99JW4. |
|
TMPY-03399
|
KLHL2 Protein, Human, Recombinant (GST)
kelch like family member 2,ABP-KELCH,MAYVEN,KLHL2,MAV
|
Human
|
E. coli
|
|
KLHL2 (Kelch Like Family Member 2) is a Protein Coding gene. 3 alternatively spliced human isoforms have been reported. KLHL2 contains 1 BTB (POZ) domain and 6 Kelch repeats. It is widely expressed in the brain, esophagus, and other tissues. KLHL2 gene has been proposed to participate in intracellular protein transportation. KLHL2 is expected to have molecular functions such as transporter activity, actin-binding, and protein binding. KLHL2 localizes in various compartments such as actin cytoske... |
|
TMPH-01256
|
Dystonin Protein, Human, Recombinant (His & SUMO)
DT,DST,BPAG1,BP240,BP230,KIAA0728,Dystonin,DMH
|
Human
|
E. coli
|
|
Cytoskeletal linker protein. Acts as an integrator of intermediate filaments, actin and microtubule cytoskeleton networks. Required for anchoring either intermediate filaments to the actin cytoskeleton in neural and muscle cells or keratin-containing intermediate filaments to hemidesmosomes in epithelial cells. The proteins may self-aggregate to form filaments or a two-dimensional mesh. Regulates the organization and stability of the microtubule network of sensory neurons to allow axonal transpo... |
|
TMPH-01257
|
Dystonin Protein, Human, Recombinant (His)
DT,BP230,Dystonin,BP240,DST,DMH,BPAG1,KIAA0728
|
Human
|
P. pastoris (Yeast)
|
|
Cytoskeletal linker protein. Acts as an integrator of intermediate filaments, actin and microtubule cytoskeleton networks. Required for anchoring either intermediate filaments to the actin cytoskeleton in neural and muscle cells or keratin-containing intermediate filaments to hemidesmosomes in epithelial cells. The proteins may self-aggregate to form filaments or a two-dimensional mesh. Regulates the organization and stability of the microtubule network of sensory neurons to allow axonal transpo... |
|
TMPH-02253
|
TPM2 Protein, Human, Recombinant (His)
TPM2,Tropomyosin-2,Tropomyosin beta chain,Beta-tropomyosin
|
Human
|
E. coli
|
|
Binds to actin filaments in muscle and non-muscle cells. Plays a central role, in association with the troponin complex, in the calcium dependent regulation of vertebrate striated muscle contraction. Smooth muscle contraction is regulated by interaction with caldesmon. In non-muscle cells is implicated in stabilizing cytoskeleton actin filaments. The non-muscle isoform may have a role in agonist-mediated receptor internalization. |
|
TMPH-03280
|
Dystrophin Protein, Rat, Recombinant (His)
Dystrophin,Dmd
|
Rat
|
P. pastoris (Yeast)
|
|
Anchors the extracellular matrix to the cytoskeleton via F-actin. Ligand for dystroglycan. Component of the dystrophin-associated glycoprotein complex which accumulates at the neuromuscular junction (NMJ) and at a variety of synapses in the peripheral and central nervous systems and has a structural function in stabilizing the sarcolemma. Also implicated in signaling events and synaptic transmission. Dystrophin Protein, Rat, Recombinant (His) is expressed in yeast with C-6xHis tag. The predicted... |
|
TMPH-01258
|
DAG1 Protein, Human, Recombinant (His & Myc)
Dystrophin-associated glycoprotein 1,Dystroglycan,Dystroglyc...
|
Human
|
Baculovirus Insect Cells
|
|
The dystroglycan complex is involved in a number of processes including laminin and basement membrane assembly, sarcolemmal stability, cell survival, peripheral nerve myelination, nodal structure, cell migration, and epithelial polarization.; Extracellular peripheral glycoprotein that acts as a receptor for extracellular matrix proteins containing laminin-G domains. Receptor for laminin-2 (LAMA2) and agrin in peripheral nerve Schwann cells. Also acts as a receptor for laminin LAMA5.; Transmembra... |
|
TMPH-02967
|
UPK3A Protein, Mouse, Recombinant (His & Myc)
Uroplakin-3a,Upk3a,Uroplakin III
|
Mouse
|
E. coli
|
|
Component of the asymmetric unit membrane (AUM); a highly specialized biomembrane elaborated by terminally differentiated urothelial cells. May play an important role in AUM-cytoskeleton interaction in terminally differentiated urothelial cells. It also contributes to the formation of urothelial glycocalyx which may play an important role in preventing bacterial adherence. UPK3A Protein, Mouse, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The pre... |
|
TMPJ-00045
|
Podoplanin Protein, Human, Recombinant (hFc)
T1A,PDPN,GP36,Podoplanin,Aggrus,T1-α,PA2.26 Antigen,T1-Alpha...
|
Human
|
HEK293 Cells
|
|
Podoplanin is a type-1 transmembrane protein that belongs to Podoplanin family. PDPN expressed in various specialized cell types throughout the body. It highly expressed in placenta, lung, skeletal muscle and brain, weakly expressed in brain, kidney and liver. In placenta, PDPN expressed on the apical plasma membrane of endothelium, in lung, expressed in alveolar epithelium. PDPN physiological function is related to its mucin-type character. PDPN may be involved in cell migration and/or actin cy... |
|
TMPH-01875
|
Plexin-B1 Protein, Human, Recombinant (His)
Semaphorin receptor SEP,PLXNB1,Plexin-B1
|
Human
|
E. coli
|
|
Receptor for SEMA4D. Plays a role in GABAergic synapse development. Mediates SEMA4A- and SEMA4D-dependent inhibitory synapse development. Plays a role in RHOA activation and subsequent changes of the actin cytoskeleton. Plays a role in axon guidance, invasive growth and cell migration. Plexin-B1 Protein, Human, Recombinant (His) is expressed in E. coli expression system with C-6xHis tag. The predicted molecular weight is 56.4 kDa and the accession number is O43157. |
|
TMPH-01751
|
Nephrin/NPHS1 Protein, Human, Recombinant (His)
Nephrin,Renal glomerulus-specific cell adhesion receptor,NPH...
|
Human
|
E. coli
|
|
Seems to play a role in the development or function of the kidney glomerular filtration barrier. Regulates glomerular vascular permeability. May anchor the podocyte slit diaphragm to the actin cytoskeleton. Plays a role in skeletal muscle formation through regulation of myoblast fusion. Nephrin/NPHS1 Protein, Human, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 29.1 kDa and the accession number is O60500. |
|
TMPJ-00943
|
Profilin 2 Protein, Human, Recombinant
Profilin-II,PFN2,PFL,Profilin-2
|
Human
|
E. coli
|
|
Profilin-II (PFN2) is ubiquitous protein which belongs to the profilin family. PFN2 binds to actin, thenaffects the structure of the cytoskeleton. At high concentrations, profiling prevents the polymerization of actin, while increases that at low concentrations. PFN2 is a ubiquitous actin monomer-binding protein. It regulates actin polymerization in response to extra cellular signals. PFN2 binds to PIP2; it inhibits the formation of IP3 and DG. |
|
TMPJ-00242
|
PARVA Protein, Human, Recombinant (His)
PARVA,CH-ILKBP,Actopaxin,Alpha-Parvin,Matrix-Remodeling-Asso...
|
Human
|
E. coli
|
|
Alpha-Parvin (PARVA) is a member of the Parvin family. PARVA contains two CH (calponin-homology) domains. PARVA is widely expressed, with highest levels in heart, skeletal muscle, kidney and liver. PARVA interacts with integrin-linked protein kinase and probably with actin and the LD1 and LD4 motifs of PXN. PARVA may play a role in the regulation of cell adhesion and cytoskeleton organization. PARVA is also involved in ciliogenesis. |
|
TMPK-01259
|
S100A9 Protein, Cynomolgus, Recombinant (His)
Calgranulin-B,MRP-14,CAGB,Calprotectin L1H subunit,MRP14,p14...
|
Cynomolgus
|
E. coli
|
|
S100A8 and S100A9 (also known as MRP8 and MRP14, respectively) are Ca2 binding proteins belonging to the S100 family. They often exist in the form of heterodimer, while homodimer exists very little because of the stability. S100A8/A9 is constitutively expressed in neutrophils and monocytes as a Ca2 sensor, participating in cytoskeleton rearrangement and arachidonic acid metabolism. S100A9 Protein, Cynomolgus, Recombinant (His) is expressed in E. coli expression system with N-His tag. The predict... |
|
TMPY-02106
|
GAP43 Protein, Human, Recombinant (His)
B-50,PP46,growth associated protein 43
|
Human
|
HEK293 Cells
|
|
Neuromodulin, also known as Axonal membrane protein GAP-43, Growth-associated protein 43, Neural phosphoprotein B-5, pp46 and GAP43, is a cell membrane protein which belongs to theneuromodulin family. Neuromodulin / GAP43 contains oneIQ domain. Neuromodulin / GAP43 is associated with nerve growth. It is a major component of the motile "growth cones" that form the tips of elongating axons. Neuromodulin / GAP43 is involved in neurite outgrowth, a crucial process for the differentiation of n... |
|
TMPJ-01387
|
PACSIN2 Protein, Human, Recombinant (His)
Protein Kinase C and Casein Kinase Substrate in Neurons Prot...
|
Human
|
HEK293 Cells
|
|
Protein Kinase C and Casein Kinase Substrate in Neurons Protein 2 (PACSIN2) is a member of the PACSIN family. PACSIN2 is localized to the plasma membrane via its coiled-coil domain. PACSIN2 is widely expressed and contains one FCH domain and one SH3 domain. PACSIN2 forms homo- and hetero-aggregates with other PACSINs. PACSIN2 may play a role in vesicle formation and transport. In addition, PACSIN2 is involved in linking the actin cytoskeleton with vesicle formation by regulating tubulin polymeri... |
|
TMPY-03392
|
CKAP1/TBCB Protein, Human, Recombinant (His)
CKAPI,tubulin folding cofactor B,CG22,CKAP1
|
Human
|
E. coli
|
|
Tubulin-folding cofactor B, also known as TBCB, belongs to the TBCB family. It contains 1 CAP-Gly domain and can be detected in most tissues. TBCB binds to alpha-tubulin folding intermediates after their interaction with cytosolic chaperonin in the pathway. The cytoskeleton is composed of 3 structural elements: actin filaments, microtubules, and intermediate filaments. TBCB is involved in regulation of tubulin heterodimer dissociation. It may function as a negative regulator of axonal growth. |
|
TMPK-01324
|
S100A9 Protein, Canine, Recombinant (His)
MRP-14,CAGB,MRP14,p14,S100-A9,Calprotectin L1H subunit,Calgr...
|
Canine
|
E. coli
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S100A8 and S100A9 (also known as MRP8 and MRP14, respectively) are Ca2 binding proteins belonging to the S100 family. They often exist in the form of heterodimer, while homodimer exists very little because of the stability. S100A8/A9 is constitutively expressed in neutrophils and monocytes as a Ca2 sensor, participating in cytoskeleton rearrangement and arachidonic acid metabolism. S100A9 Protein, Canine, Recombinant (His) is expressed in E. coli expression system with N-His tag. The predicted m... |
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TMPH-03213
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TPM1 Protein, Rabbit, Recombinant (E. coli, His & Myc)
Tropomyosin alpha-1 chain,TPM1,Alpha-tropomyosin,Tropomyosin...
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Rabbit
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E. coli
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Binds to actin filaments in muscle and non-muscle cells. Plays a central role, in association with the troponin complex, in the calcium dependent regulation of vertebrate striated muscle contraction. Smooth muscle contraction is regulated by interaction with caldesmon. In non-muscle cells is implicated in stabilizing cytoskeleton actin filaments. TPM1 Protein, Rabbit, Recombinant (E. coli, His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular w... |
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TMPH-03212
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TPM1 Protein, Rabbit, Recombinant (His & Myc)
TPM1,Alpha-tropomyosin,Tropomyosin alpha-1 chain,Tropomyosin...
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Rabbit
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Baculovirus Insect Cells
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Binds to actin filaments in muscle and non-muscle cells. Plays a central role, in association with the troponin complex, in the calcium dependent regulation of vertebrate striated muscle contraction. Smooth muscle contraction is regulated by interaction with caldesmon. In non-muscle cells is implicated in stabilizing cytoskeleton actin filaments. TPM1 Protein, Rabbit, Recombinant (His & Myc) is expressed in Baculovirus insect cells with N-10xHis and C-Myc tag. The predicted molecular weight is 3... |
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