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31

抑制剂 & 化合物

8

天然产物

1

化合物库

24

重组蛋白

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Cat. No.	Product Name
L6000	高通量筛选天然产物库		4533 compounds
	4533 种天然产物的独特集合，是药物开发、药理研究、干细胞分化、指纹图谱研究、质量研究等领域的有力工具，可用于HTS 和HCS；

化合物库

高通量筛选天然产物库

Cat.No: L6000

Compounds: 4533

Cat. No.	Product Name	Target	Signaling Pathways
T19780	2,2′-Dipyridyl disulfide 2,2'-Dipyridyl disulfide,OPSS,2,2'-二硫二吡啶,Aldrithiol 2,Orthopyridyl disulfide	Others	Others
	2,2′-Dipyridyl disulfide (Aldrithiol 2) 是肽化学中的常用试剂，是测定巯基的有用试剂，常用于氧化还原缩合以形成肽键或用于偶联反应以形成二硫键连接的异二聚体。
T15212	Emamectin Benzoate MK-244,甲胺基阿维菌素苯甲酸盐	Apoptosis; Reactive Oxygen Species; GABA Receptor; Parasite	Apoptosis; Immunology/Inflammation; Membrane transporter/Ion channel; Metabolism; Microbiology/Virology; Neuroscience; NF-κB
	Emamectin Benzoate (MK-244) 是口服有效的神经系统毒物，其通过结合昆虫中的 GABA 受体发挥作用。它是阿维菌素的半合成衍生物之一，具有广谱的杀虫和杀螨活性。它诱导ROS 介导的 DNA 损伤和细胞凋亡。
T5651	Phenyl benzoate	Others	Others
	Phenyl benzoate 是苯酚与苯甲酸缩合而成的苯甲酸酯，是重要的有机合成中间体。
T8915	Glycylsarcosine GLYCYL-SARCOSINE,甘氨酰肌氨酸	Others	Others
	Glycylsarcosine (GLYCYL-SARCOSINE) 是由甘氨酸的羧基与肌氨酸的氨基缩合而成的二肽
T22364	Methyl 4-aminobutyrate HCl 4-氨基丁酸甲酯盐酸盐,Methyl 4-aminobutyrate hydrochloride,GABA methyl ester	Others	Others
	Methyl 4-aminobutyrate HCl (GABA methyl ester) 是一种由氨基丁酸和甲醇缩合而成的甲酯化合物。
T13623	Compound 48/80 trihydrochloride C48/80 trihydrochloride	Phospholipase	Metabolism
	Compound 48/80 trihydrochloride (C48/80 trihydrochloride) 是 N-甲基对甲氧基苯乙胺和甲醛发生缩合反应后的混合物。Compound 48/80 trihydrochloride 是一种肥大细胞 (mast cell) 脱颗粒剂和组胺 (histamine) 释放剂。Compound 48/80 trihydrochloride 对人血小板磷脂酰肌醇特异性磷脂酶 C (phosphatidylinositol-specific phospholipase C) 活性有抑制作用。
T7739	L-Leucyl-L-Leucine methyl ester hydrochloride Leu-Leu-ome hydrochloride	Others; Endogenous Metabolite	Metabolism; Others
	L-Leucyl-L-Leucine methyl ester hydrochloride (Leu-Leu-ome hydrochloride) 是一种人单核细胞或多形核白细胞产生的 L-亮氨酸甲酯的二肽缩合产物，能够选择性消除具有细胞毒性潜能的淋巴细胞，也能够诱导溶酶体途径应激。
T36879L	H-Leu-Leu-OMe . HBr H-Leu-Leu-OMe . HBr (16689-14-8 Free base)	Others	Others
	H-Leu-Leu-OMe . HBr 是由人单核细胞或多形核白细胞产生的L-亮氨酸甲酯的二肽缩合产物。 H-Leu-Leu-OMe . HBr 诱导内溶酶体途径应激并选择性地消除具有细胞毒性潜力的淋巴细胞。
T2186	Tris(2,2,2-trifluoroethyl) borate SL 75212,硼酸三酯(2,2,2-三氟乙基)	Others	Others
	Tris(2,2,2-trifluoroethyl) borate (SL 75212) 主要用于缩合反应。它已被证明可以促进羧酸和胺直接形成酰胺，以及胺或酰胺与羰基化合物形成亚胺。
T20334	Furoin NSC 18522,NSC18522,NSC-18522	Others	Others
	Furoin is an organic compound. It can be produced from furfural by a benzoin condensation reaction catalyzed by cyanide ions.
T32600	Lauroylmethionine N-Lauroyl-L-methionine,Lauroyl-L-methionine	Others	Others
	Lauroylmethionine is a lysine salt of the product formed by the condensation of lauroyl fatty acid chloride with methionine.
T38132	(S)-Higenamine hydrobromide	Others	Others
	(S)-Higenamine hydrobromide, an S-enantiomer of Higenamine, serves as the preliminary compound in benzylisoquinoline alkaloid biosynthesis. It is formed through the condensation of dopamine and 4-hydroxyphenylacetaldehyde (4-HPAA) via norcoclaurine synthase (NCS)[1].
T20780	Dibutyltin maleate Stavinor Sn 1300,Stavinor 1300SN	Others	Others
	Dibutyltin maleate is used as a condensation catalyst and pvc Stabilizer.
T74039	Arachidonoyl coenzyme A lithium	Others	Others
	Arachidonoyl coenzyme A lithium是一种由辅酶A的硫醇基与花生四烯酸的羧基缩合生成的不饱和脂肪酰基辅酶A。
T84423	5-PAHSA 5-PAHSA,5-(palmitoyloxy)octadecanoic acid	Others	Others
	5-PAHSA, a FAHFA formed through the formal condensation of the carboxy group of palmitic acid with the hydroxy group of 5-hydroxystearic acid, serves as a human metabolite, possesses anti-inflammatory and hypoglycemic properties, and is categorized as a long-chain fatty acid. This compound, deriving from hexadecanoic acid and octadecanoic acid, is the conjugate acid of a 5-PAHSA(1-).
T9538	3,5-Di-tert-butylbenzaldehyde	Others	Others
	3,5-Di-tert-butylbenzaldehyde 可用于合成化合物。
T75641	(S)-Higenamine	Others	Others
	(S)-Higenamine ((S)-Norcoclaurine)，一种苄基异喹啉生物碱，作为其生物合成路径中的起始化合物，通过去甲月桂碱合酶(NCS)催化多巴胺与4-羟基苯乙醛(4-HPAA)的缩合反应形成。
T85174	3-keto Sphinganine (d12:0) hydrochloride 3-keto Sphinganine (d12:0),3-keto Dihydrosphingosine (d12:0)	Others	Others
	3-Keto Sphinganine (d12:0) is a short-chain analog of 3-keto sphinganine (d18:0), which typically possesses a C18 chain length. The latter is a lyso-sphingolipid synthesized through the condensation of L-serine and palmitoyl-CoA mediated by the enzyme serine palmitoyl transferase (SPT). A deficiency in Vitamin K deactivates SPT, leading to a reduced synthesis of 3-keto sphinganine among other sphingolipids. [Matreya, LLC. Catalog No. 1893]
T76165	N-Acetylneuraminate lyase (CgNal)
	N-Acetylneuraminate lyase (CgNal)（亦称Sialic acid aldolase (CgNal)）是一种醛缩酶，在生化研究中有着广泛应用。该酶催化丙酮酸和N-acetyl-d-mannosamine (ManNAc) 通过一种可逆的缩合反应生成sialic acid N-acetylneuraminic acid (Neu5Ac)。
T35454	γ-Glu-Cys (ammonium salt)	Others	Others
	γ-Glu-Cys is an intermediate in glutathione (GSH) synthesis.1It is formed by ATP-dependent condensation of cysteine and glutamate by γ-glutamylcysteine synthetase. γ-Glu-Cys is also an essential component of phytochelatins, the heavy metal detoxifying enzymes in plants.2
T73753	Neuraminic acid	Others	Others
	Neuraminic acid是由9个碳原子的主链构成的酸性氨基糖，也是丙酮酸与D-甘露胺(2-氨基-2-脱氧甘露糖)醛酸经缩合反应生成的产物。它作为具有生物活性的黏液蛋白的官能团。
T37584	Tryptoquivaline D	Others	Others
	Tryptoquivaline D is a fungal metabolite that has been found inNeosartorya siamensisand has anticancer activity.1,2It induces nuclear chromatin condensation, a marker of apoptosis, in HCT116 colon and HepG2 liver cancer cells when used at a concentration of 150 μM.1Tryptoquivaline D (1-100 μM), alone or in combination with doxorubicin , reduces the viability of A549 lung cancer cells.2
T85028	1,1'-(Azodicarbonyl)dipiperidine ADDP,NSC 356027	Others	Others
	1,1'-(Azodicarbonyl)dipiperidine (ADDP) serves as a widely employed reagent in the Mitsunobu reaction, facilitating the condensation between an alcohol and an acidic compound. Moreover, ADDP has found application in synthesizing agonists for the G protein-coupled receptor 120 (GPR120) with potential antidiabetic effects as well as in the creation of triple agonists for peroxisome proliferator-activated receptor α (PPARα), PPARγ, and PPARδ.
T83949	DC 432	Others	Others
	DC 432是一种强效的N-terminal methyltransferase 1/2 (NTMT1/2) (IC50= 54 nM)肽模拟抑制剂，含有BM30肽和额外五个精氨酸残基。在HCT116细胞中，DC 432处理能够降低调节染色体凝缩1和SET蛋白的N端甲基化水平。该化合物具有细胞渗透性。
T70770	Cyclazosin Free Base	Others	Others
	Cyclazosin Free Base is a monocarboxylic acid amide obtained by formal condensation of the carboxy group of furoic acid with the secondary amino group of 6,7-dimethoxy-2-[(4aR,8aS)-octahydroquinoxalin-1-yl]quinazolin-4-amine. It has a role as an adenosine A2A receptor antagonist. It is a member of quinazolines, a member of furans, an aromatic ether, a quinoxaline derivative, an aromatic amide and a monocarboxylic acid amide.
T78520	CYT296	Others	Others
	CYT296是一种靶向染色质去凝集的化合物，能增强定义因子(OSKM)介导诱导多能干细胞(iPSC)的生成，并通过诱导小鼠胚胎成纤维细胞(MEFs)染色质的开放状态来促进体细胞的重编程，适用于细胞替代治疗和药物筛选的研究领域。
T36731	Cholesteryl Heptadecanoate	Others	Others
	Cholesteryl heptadecanoate is a cholesterol ester (CE) formed by the condensation of cholesterol with heptadecanoic acid, a C-17 saturated fatty acid that does not occur in any natural animal or vegetable fat at high concentrations. As such, it is commonly used as an internal standard for the quantification of cholesterol esters by GC- or LC-mass spectrometry. CEs are major constituents of lipoprotein particles carried in blood and accumulate in the fatty acid lesions of atherosclerotic plaques....
T85010	Sphingosine (d16:1) D-erythro-Sphingosine C-16	Others	Others
	Sphingosine (d16:1), an unconventional sphingolipid, is synthesized through enzymatic reactions starting with the condensation of myristoyl-CoA and serine by serine palmitoyltransferase long-chain base subunit 3 (SPTLC3), which shows a preference for myristoyl-CoA. This compound is found in minute quantities in its free form in human plasma and as a component of various plasma sphingolipids, such as sphingosine-1-phosphate, ceramides, sphingomyelins, and in brain cerebrosides, albeit at lower co...
T83886	icFSP1 TFA	Others	Others
	icFSP1是一种抑制剂，针对的是铁死亡抑制蛋白1（FSP1）。在2.5 µM的浓度下使用时，能够引发FSP1在细胞中的凝聚和相分离，但在无细胞测试中并不抑制FSP1的酶活性（IC50 = > 30 µM）。icFSP1以浓度依赖的方式诱导HT-1080纤维肉瘤细胞的铁死亡。在体内，icFSP1（50 mg/kg）通过使用人类过表达FSP1，Gpx4-/-Fsp1-/-的B16/F10细胞，在B16/F10鼠黑色素瘤模型中减少肿瘤体积和重量。
T83713	DC432 TFA
	DC432是一种细胞内可渗透的肽类抑制剂，针对N-末端Xaa-Pro-Lys N-甲基转移酶1 (NTMT1; IC50 = 0.054 µM)。该化合物与NTMT1和NTMT2有结合作用（Kds分别为0.3和1 µM），并在10和50 µM的浓度下，通过细胞外实验抑制NTMT1对调节染色体凝缩1 (RCC1) N-末端二甲基化。DC432（100 µM）在HCT116细胞中减少了RCC1 SPKRIA基序的三甲基化。
T78855	Anticancer agent 157	NO Synthase	Immunology/Inflammation
	Anticanceragent 157（compound 15）是一种NO抑制剂，具有抗炎和抗癌特性，IC50值为0.62 μg/mL。它能够与iNOS和caspase 8结合，进而导致核断裂和染色质浓缩，从而诱导细胞凋亡。此外，Anticanceragent 157在不同癌细胞系中展现出显著的抑制活性，对HT29结肠癌细胞的IC50为2.45 μg/mL，对Hep-G2肝癌细胞的IC50为3.25 μg/mL，以及对B16-F10鼠黑色素瘤细胞的IC50为3.84 μg/mL。

化合物

2,2′-Dipyridyl disulfide

Cat.No: T19780

Synonym: 2,2'-Dipyridyl disulfide,OPSS,2,2'-二硫二吡啶,Aldrithiol 2,Orthopyridyl disulfide

Target: Others

Emamectin Benzoate

Cat.No: T15212

Synonym: MK-244,甲胺基阿维菌素苯甲酸盐

Target: Apoptosis, Reactive Oxygen Species, GABA Receptor, Parasite

Phenyl benzoate

Cat.No: T5651

Target: Others

Glycylsarcosine

Cat.No: T8915

Synonym: GLYCYL-SARCOSINE,甘氨酰肌氨酸

Target: Others

Methyl 4-aminobutyrate HCl

Cat.No: T22364

Synonym: 4-氨基丁酸甲酯盐酸盐,Methyl 4-aminobutyrate hydrochloride,GABA methyl ester

Target: Others

Compound 48/80 trihydrochloride

Cat.No: T13623

Synonym: C48/80 trihydrochloride

Target: Phospholipase

L-Leucyl-L-Leucine methyl ester hydrochloride

Cat.No: T7739

Synonym: Leu-Leu-ome hydrochloride

Target: Others, Endogenous Metabolite

H-Leu-Leu-OMe . HBr

Cat.No: T36879L

Synonym: H-Leu-Leu-OMe . HBr (16689-14-8 Free base)

Target: Others

Tris(2,2,2-trifluoroethyl) borate

Cat.No: T2186

Synonym: SL 75212,硼酸三酯(2,2,2-三氟乙基)

Target: Others

Cat.No: T20334

Synonym: NSC 18522,NSC18522,NSC-18522

Target: Others

Lauroylmethionine

Cat.No: T32600

Synonym: N-Lauroyl-L-methionine,Lauroyl-L-methionine

Target: Others

(S)-Higenamine hydrobromide

Cat.No: T38132

Target: Others

Dibutyltin maleate

Cat.No: T20780

Synonym: Stavinor Sn 1300,Stavinor 1300SN

Target: Others

Arachidonoyl coenzyme A lithium

Cat.No: T74039

Target: Others

Cat.No: T84423

Synonym: 5-PAHSA,5-(palmitoyloxy)octadecanoic acid

Target: Others

3,5-Di-tert-butylbenzaldehyde

Cat.No: T9538

Target: Others

Cat.No: T75641

Target: Others

3-keto Sphinganine (d12:0) hydrochloride

Cat.No: T85174

Synonym: 3-keto Sphinganine (d12:0),3-keto Dihydrosphingosine (d12:0)

Target: Others

N-Acetylneuraminate lyase (CgNal)

Cat.No: T76165

γ-Glu-Cys (ammonium salt)

Cat.No: T35454

Target: Others

Neuraminic acid

Cat.No: T73753

Target: Others

Tryptoquivaline D

Cat.No: T37584

Target: Others

1,1'-(Azodicarbonyl)dipiperidine

Cat.No: T85028

Synonym: ADDP,NSC 356027

Target: Others

Cat.No: T83949

Target: Others

Cyclazosin Free Base

Cat.No: T70770

Target: Others

Cat.No: T78520

Target: Others

Cholesteryl Heptadecanoate

Cat.No: T36731

Target: Others

Sphingosine (d16:1)

Cat.No: T85010

Synonym: D-erythro-Sphingosine C-16

Target: Others

Cat.No: T83886

Target: Others

Cat.No: T83713

Anticancer agent 157

Cat.No: T78855

Target: NO Synthase

Cat. No.	Product Name	Target	Signaling Pathways
T8042	2-Acetylthiazole 2-Acetylthiazole;2 Acetylthiazole,2-Acetylthiazole,2-Thiazolyl methyl ketone,2 Acetylthiazole,1-(2-Thiazolyl)ethanone	Others	Others
	2-Acetylthiazole (2-Acetylthiazole;2 Acetylthiazole) 用于制备手性醇、三唑并噻唑，也用于羟醛缩合反应。
T37298	Spinacine	Endogenous Metabolite	Metabolism
	Spinacine 是人内源性代谢产物。
T1705	5-Amino-3H-imidazole-4-Carboxamide 4-Amino-5-imidazolecarboxamide,AICA,4-氨基-5-咪唑甲酰胺,5-Aminoimidazole-4-carboxamide	Endogenous Metabolite	Metabolism
	5-Amino-3H-imidazole-4-Carboxamide (AICA) 是一种合成嘌呤（尤其是核碱基腺嘌呤和鸟嘌呤）的重要前体。
T19316	Ethyl oleate	Others	Others
	Ethyl oleate 是由油酸和乙醇的缩合形成的脂肪酸酯。它是纳米结构脂质载体 (NLC) 中的液体脂质成分。其中 NLC 是一种口服有活性的反式阿魏酸的给药载体。
T5238	1,2-Dipalmitoyl-sn-glycero-3-phosphoethanolamine 1,2-Dipalmitoyl-sn-glycero-3-PE,L-磷脂酰乙醇胺,1,2-Dipalmitoyl-sn-glycerol-3-Phosphoethanolamine,1,2-DPPE	Others; Endogenous Metabolite	Metabolism; Others
	1,2-Dipalmitoyl-sn-glycero-3-phosphoethanolamine (DPPE) 是内源性代谢产物的一种。
T6S2391	L-Chicoric Acid (-)-Chicoric acid,trans-Caffeoyltartaric acid,Chicoric acid,L-菊苣酸,dicaffeoyltartaric acid,菊苣酸	Others; HIV Protease	Microbiology/Virology; Others; Proteases/Proteasome
	L-Chicoric Acid (trans-Caffeoyltartaric acid) 是一种二咖啡酰酒石酸，是一种选择性可逆的 HIV-1 整合酶抑制剂，IC50约为 100 nM。它还可抑制 HIV-1 复制。
T75639	Cellohexaose	Others	Others
	Cellohexaose，一种由β(1-4)链接的D-葡萄糖单体通过缩合反应形成的葡萄糖聚合物，来源于纤维素的分解，包含两个或更多的葡萄糖单体。
TN7291	2-Deoxyribose 5-phosphate disodium	Others	Others
	2-Deoxyribose 5-phosphate disodium 是一种2-deoxyribose-5-phosphate aldolase (DERA) 的底物，该酶为I类醛缩酶，负责催化可逆醛缩反应，且在过程中不需要任何辅助因子。

天然产物

2-Acetylthiazole

Cat.No: T8042

Synonym: 2-Acetylthiazole;2 Acetylthiazole,2-Acetylthiazole,2-Thiazolyl methyl ketone,2 Acetylthiazole,1-(2-Thiazolyl)ethanone

Target: Others

Cat.No: T37298

Target: Endogenous Metabolite

5-Amino-3H-imidazole-4-Carboxamide

Cat.No: T1705

Synonym: 4-Amino-5-imidazolecarboxamide,AICA,4-氨基-5-咪唑甲酰胺,5-Aminoimidazole-4-carboxamide

Target: Endogenous Metabolite

Cat.No: T19316

Target: Others

1,2-Dipalmitoyl-sn-glycero-3-phosphoethanolamine

Cat.No: T5238

Synonym: 1,2-Dipalmitoyl-sn-glycero-3-PE,L-磷脂酰乙醇胺,1,2-Dipalmitoyl-sn-glycerol-3-Phosphoethanolamine,1,2-DPPE

Target: Others, Endogenous Metabolite

L-Chicoric Acid

Cat.No: T6S2391

Synonym: (-)-Chicoric acid,trans-Caffeoyltartaric acid,Chicoric acid,L-菊苣酸,dicaffeoyltartaric acid,菊苣酸

Target: Others, HIV Protease

Cat.No: T75639

Target: Others

2-Deoxyribose 5-phosphate disodium

Cat.No: TN7291

Target: Others

Species：

Expression System：

Tag：

Cat. No.	Product Name	Species	Expression System
TMPH-01236	DFFB Protein, Human, Recombinant (His) DNA fragmentation factor 40 kDa subunit,Caspase-activated DN...	Human	E. coli
	Nuclease that induces DNA fragmentation and chromatin condensation during apoptosis. Degrades naked DNA and induces apoptotic morphology.
TMPH-03524	KAS III Protein, S. aureus, Recombinant (His & Myc) 3-oxoacyl-[acyl-carrier-protein] synthase 3,3-oxoacyl-[acyl-...	Staphylococcus aureus	E. coli
	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids. KAS III Protein, S. au...
TMPH-02817	OTCase Protein, Mouse, Recombinant (His & SUMO) Ornithine carbamoyltransferase, mitochondrial,Otc,Ornithine ...	Mouse	E. coli
	Catalyzes the second step of the urea cycle, the condensation of carbamoyl phosphate with L-ornithine to form L-citrulline. The urea cycle ensures the detoxification of ammonia by converting it to urea for excretion.
TMPH-03045	NadA Protein, MenB, Recombinant (His) Quinolinate synthase,nadA	MenB	E. coli
	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate.
TMPH-03585	Dihydropteroate synthase Protein, S. haemolyticus, Recombinant (His) folP,Dihydropteroate synthase,DHPS,Dihydropteroate pyrophosp...	Staphylococcus haemolyticus	E. coli
	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives. Dihydropteroate synthase Protein, S. haemolyticus, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 33.6 kDa and the accession number is Q59919.
TMPH-00335	FBA1 Protein, Candida albicans, Recombinant (His & Myc) Fructose-1,6-bisphosphate aldolase,IgE-binding allergen,Fruc...	Candida albicans	E. coli
	Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis. FBA1 Protein, Candida albicans, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 46.5 kDa and the accession number is Q9URB4.
TMPH-03047	NadA Protein, MenC, Recombinant (His) Quinolinate synthase,nadA	MenB	E. coli
	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate. NadA Protein, MenC, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 44.1 kDa and the accession number is A1KVN9.
TMPH-01477	Histone H1.3 Protein, Human, Recombinant (His & MBP) Histone H1s-2,H1-3,Histone H1.3,Histone H1c	Human	E. coli
	Histone H1 protein binds to linker DNA between nucleosomes forming the macromolecular structure known as the chromatin fiber. Histones H1 are necessary for the condensation of nucleosome chains into higher-order structured fibers. Acts also as a regulator of individual gene transcription through chromatin remodeling, nucleosome spacing and DNA methylation. HIST1H1D Protein, Human, Recombinant (His & MBP) is expressed in E. coli expression system with N-MBP and C-6xHis tag. The predicted molecula...
TMPH-00709	DAHP synthase Protein, E. coli, Recombinant (His) Phospho-2-dehydro-3-deoxyheptonate aldolase, Trp-sensitive,P...	E. coli	E. coli
	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D-arabino-heptulosonate-7-phosphate (DAHP). DAHP synthase Protein, E. coli, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 42.8 kDa and the accession number is P00887.
TMPH-03402	STR1 Protein, Rauvolfia serpentina, Recombinant (His & Myc) STR1,Strictosidine synthase	Rauvolfia serpentina	E. coli
	Catalyzes the stereospecific condensation of tryptamine with secologanin to form strictosidine, the key intermediate of indole alkaloid biosynthesis. STR1 Protein, Rauvolfia serpentina, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 43.2 kDa and the accession number is P68175.
TMPJ-00483	DFF45 Protein, Human, Recombinant (His) DNA Fragmentation Factor Subunit Alpha,DFF45,H13,ICAD,DFFA,D...	Human	E. coli
	DNA Fragmentation Factor Subunit Alpha (DFFA). DFFA exists as a heterodimer (DFF) with DFFB. DFF is activated once DFFA is cleaved by Caspase-3. The cleaved fragments of DFFA detach from DFFB (the active component of DFF), which in turn triggers DNA fragmentation as well as chromatin condensation during apoptosis. A reduced level of DFFA detected in ovarian endometriosis may be a part of an apoptosis-resistant mechanism enhancing the disease progression.
TMPH-02717	HMGCS1 Protein, Mouse, Recombinant (His & SUMO) Hmgcs1,3-hydroxy-3-methylglutaryl coenzyme A synthase,Hydrox...	Mouse	E. coli
	Catalyzes the condensation of acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is converted by HMG-CoA reductase (HMGCR) into mevalonate, a precursor for cholesterol synthesis. HMGCS1 Protein, Mouse, Recombinant (His & SUMO) is expressed in E. coli expression system with N-6xHis-SUMO tag. The predicted molecular weight is 73.6 kDa and the accession number is Q8JZK9.
TMPH-02993	DisA Protein, Mycobacterium paratuberculosis, Recombinant (His & Myc) disA,c-di-AMP synthase,DNA integrity scanning protein DisA,D...	Mycobacterium paratuberculosis	E. coli
	Participates in a DNA-damage check-point. DisA forms globular foci that rapidly scan along the chromosomes searching for lesions.; Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c-di-AMP likely acts as a signaling molecule that may couple DNA integrity with a cellular process. DisA Protein, Mycobacterium paratuberculosis, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predict...
TMPH-01817	OTCase Protein, Human, Recombinant (His & SUMO) Ornithine carbamoyltransferase, mitochondrial,OTC,Ornithine ...	Human	E. coli
	Catalyzes the second step of the urea cycle, the condensation of carbamoyl phosphate with L-ornithine to form L-citrulline. The urea cycle ensures the detoxification of ammonia by converting it to urea for excretion. OTCase Protein, Human, Recombinant (His & SUMO) is expressed in E. coli expression system with N-6xHis-SUMO tag. The predicted molecular weight is 52.1 kDa and the accession number is P00480.
TMPH-02205	Titin Protein, Human, Recombinant (His) Connectin,TTN,Rhabdomyosarcoma antigen MU-RMS-40.14,Titin	Human	E. coli
	Key component in the assembly and functioning of vertebrate striated muscles. By providing connections at the level of individual microfilaments, it contributes to the fine balance of forces between the two halves of the sarcomere. The size and extensibility of the cross-links are the main determinants of sarcomere extensibility properties of muscle. In non-muscle cells, seems to play a role in chromosome condensation and chromosome segregation during mitosis. Might link the lamina network to ch...
TMPJ-00732	ASS1 Protein, Human, Recombinant (His) Citrulline--Aspartate Ligase,Argininosuccinate Synthase,ASS1...	Human	E. coli
	Argininosuccinate Synthase (ASS1) is an urea cycle enzyme with a tetrameric structure composed of identical subunits. ASS1 is involved in the synthesis of arginine and catalyzes that condensation of citrulline and aspartate to argininosuccinate using ATP. ASS1 is important to the urea cycle as it catalyzes the important second last step in the arginine biosynthetic pathway. ASS1 mainly expressed in periportal hepatocytes, but also in most other body tissues. A deficiency of ASS1 causes citrullin...
TMPJ-00806	HMBS Protein, Human, Recombinant (His) Pre-Uroporphyrinogen Synthase,PBG-D,Hydroxymethylbilane Synt...	Human	HEK293 Cells
	Porphobilinogen Deaminase (HMBS) is a member of the HMBS family. PBGD is the third enzyme of the heme biosynthetic pathway and catalyzes the head to tail condensation of four porphobilinogen molecules into the linear hydroxymethylbilane. HMBS is involved in the production of heme, which is important for all of the body's organs, although it is most abundant in the blood, bone marrow, and liver. In addition, Heme is an essential component of iron-containing proteins called hemoproteins, including...
TMPY-04420	TLK1 Protein, Human, Recombinant (His & GST) KIAA0137,PKU-beta,tousled like kinase 1,PKU-β	Human	Baculovirus Insect Cells
	Tousled-like kinase 1 (or protein kinase ubiquitous, PKU-beta/TLK1) is a serine/threonine protein kinase that is implicated in chromatin remodeling, DNA replication and mitosis. TLK1 has a function important for proper chromosome segregation and maintenance of diploid cells at mitosis in mammalian cells that could be mediated by reduced phosphorylation of histone H3 and condensation of chromosomes, although other explanations to the phenotype are possible.
TMPJ-00979	GSH-S Protein, Human, Recombinant (His) Glutathione Synthetase,GSS,GSH-S,GSH Synthetase,Glutathione ...	Human	E. coli
	Glutathione Synthetase belongs to the eukaryotic GSH synthase family. Glutathione Synthetase is the second enzyme in the glutathione biosynthesis pathway. It catalyses the condensation of gamma-glutamylcysteine and glycine to form glutathione. Glutathione play an important role in a variety of biological functions, including detoxification of xenobiotics, protection of cells from oxidative damage by free radicals, and membrane transport. The protein functions as a homodimer to catalyze the secon...
TMPY-02577	NAMPT Protein, Human, Recombinant (His & GST) VISFATIN,PBEF,PBEF1,1110035O14Rik,VF,nicotinamide phosphorib...	Human	Baculovirus Insect Cells
	Nicotinamide phosphoribosyltransferase (NAMPT), also known as pre-B-cell colony-enhancing factor 1 (PBEF1) or visfatin, is an enzyme belonging to the family of glycosyltransferases, to be specific, the pentosyltransferases. This enzyme participates in nicotinate and nicotinamide metabolism. This enzyme catalyzes the condensation of nicotinamide with 5- phosphoribosyl-1- pyrophosphate to yield nicotinamide mononucleotide, one step in the biosynthesis of nicotinamide adenine dinucleotide. NAMPT is...
TMPH-02997	Dps Protein, Mycobacterium smegmatis, Recombinant (His & SUMO) Neutrophil-activating protein A,NAP A,HP-NAP,Bacterioferriti...	Mycobacterium smegmatis	E. coli
	Protects DNA from oxidative damage by sequestering intracellular Fe(2+) ion and storing it in the form of Fe(3+) oxyhydroxide mineral. One hydrogen peroxide oxidizes two Fe(2+) ions, which prevents hydroxyl radical production by the Fenton reaction. It protects DNA from hydroxyl radical-mediated cleavage. Binds DNA with no apparent sequence specificity without self-aggregation nor promotion of DNA condensation. Is unable to protect DNA from DNase-mediated cleavage. Dps Protein, Mycobacterium sme...
TMPY-03406	NMNAT1 Protein, Human, Recombinant (His) PNAT1,LCA9,nicotinamide nucleotide adenylyltransferase 1,NMN...	Human	Baculovirus Insect Cells
	NMNAT, also known as NMNAT1, is a member of the Nicotinamide-nucleotide adenylyltransferases. It is widely expressed with high levels in skeletal muscle, heart, liver, and kidney. NMNAT appears to have the ability to protect against axonal degeneration following mechanical or toxic insults. The coenzyme NAD and its derivatives are involved in hundreds of metabolic redox reactions and are utilized in protein ADP-ribosylation, histone deacetylation, and in some Ca(2+) signaling pathways. NMNAT enz...
TMPH-00711	BioH Protein, E. coli, Recombinant (His & Myc) bioB,Carboxylesterase BioH,Biotin synthesis protein BioH,Pim...	E. coli	E. coli
	The physiological role of BioH is to remove the methyl group introduced by BioC when the pimeloyl moiety is complete. It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway through the hydrolysis of the ester bonds of pimeloyl-ACP esters. E.coli employs a methylation and demethylation strategy to allow elongation of a temporarily disguised malonate moiety to a pimelate moiety by the fatty acid synthetic enzymes. BioH shows a preference for short chain fatty acid esters (acyl c...
TMPH-00616	DNA-binding protein H-NS Protein, E. coli, Recombinant (His) hns,DNA-binding protein H-NS,Protein B1,Protein H1,Heat-stab...	E. coli	E. coli
	A DNA-binding protein implicated in transcriptional repression (silencing). Also involved in bacterial chromosome organization and compaction. H-NS binds tightly to AT-rich dsDNA and inhibits transcription. Binds upstream and downstream of initiating RNA polymerase, trapping it in a loop and preventing transcription. Binds to hundreds of sites, approximately half its binding sites are in non-coding DNA, which only accounts for about 10% of the genome. Many of these loci were horizontally transfe...

重组蛋白

DFFB Protein, Human, Recombinant (His)

Cat.No: TMPH-01236

Species: Human

Expression System: E. coli

KAS III Protein, S. aureus, Recombinant (His & Myc)

Cat.No: TMPH-03524

Species: Staphylococcus aureus

Expression System: E. coli

OTCase Protein, Mouse, Recombinant (His & SUMO)

Cat.No: TMPH-02817

Species: Mouse

Expression System: E. coli

NadA Protein, MenB, Recombinant (His)

Cat.No: TMPH-03045

Species: MenB

Expression System: E. coli

Dihydropteroate synthase Protein, S. haemolyticus, Recombinant (His)

Cat.No: TMPH-03585

Species: Staphylococcus haemolyticus

Expression System: E. coli

FBA1 Protein, Candida albicans, Recombinant (His & Myc)

Cat.No: TMPH-00335

Species: Candida albicans

Expression System: E. coli

NadA Protein, MenC, Recombinant (His)

Cat.No: TMPH-03047

Species: MenB

Expression System: E. coli

Histone H1.3 Protein, Human, Recombinant (His & MBP)

Cat.No: TMPH-01477

Species: Human

Expression System: E. coli

DAHP synthase Protein, E. coli, Recombinant (His)

Cat.No: TMPH-00709

Species: E. coli

Expression System: E. coli

STR1 Protein, Rauvolfia serpentina, Recombinant (His & Myc)

Cat.No: TMPH-03402

Species: Rauvolfia serpentina

Expression System: E. coli

DFF45 Protein, Human, Recombinant (His)

Cat.No: TMPJ-00483

Species: Human

Expression System: E. coli

HMGCS1 Protein, Mouse, Recombinant (His & SUMO)

Cat.No: TMPH-02717

Species: Mouse

Expression System: E. coli

DisA Protein, Mycobacterium paratuberculosis, Recombinant (His & Myc)

Cat.No: TMPH-02993

Species: Mycobacterium paratuberculosis

Expression System: E. coli

OTCase Protein, Human, Recombinant (His & SUMO)

Cat.No: TMPH-01817

Species: Human

Expression System: E. coli

Titin Protein, Human, Recombinant (His)

Cat.No: TMPH-02205

Species: Human

Expression System: E. coli

ASS1 Protein, Human, Recombinant (His)

Cat.No: TMPJ-00732

Species: Human

Expression System: E. coli

HMBS Protein, Human, Recombinant (His)

Cat.No: TMPJ-00806

Species: Human

Expression System: HEK293 Cells

TLK1 Protein, Human, Recombinant (His & GST)

Cat.No: TMPY-04420

Species: Human

Expression System: Baculovirus Insect Cells

GSH-S Protein, Human, Recombinant (His)

Cat.No: TMPJ-00979

Species: Human

Expression System: E. coli

NAMPT Protein, Human, Recombinant (His & GST)

Cat.No: TMPY-02577

Species: Human

Expression System: Baculovirus Insect Cells

Dps Protein, Mycobacterium smegmatis, Recombinant (His & SUMO)

Cat.No: TMPH-02997

Species: Mycobacterium smegmatis

Expression System: E. coli

NMNAT1 Protein, Human, Recombinant (His)

Cat.No: TMPY-03406

Species: Human

Expression System: Baculovirus Insect Cells

BioH Protein, E. coli, Recombinant (His & Myc)

Cat.No: TMPH-00711

Species: E. coli

Expression System: E. coli

DNA-binding protein H-NS Protein, E. coli, Recombinant (His)

Cat.No: TMPH-00616

Species: E. coli

Expression System: E. coli

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