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TMPH-00985
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NPR3 Protein, Human, Recombinant (His)
Atrial natriuretic peptide receptor type C,Atrial natriureti...
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Human
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E. coli
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Receptor for the natriuretic peptide hormones, binding with similar affinities atrial natriuretic peptide NPPA/ANP, brain natriuretic peptide NPPB/BNP, and C-type natriuretic peptide NPPC/CNP. May function as a clearance receptor for NPPA, NPPB and NPPC, regulating their local concentrations and effects. May regulate diuresis, blood pressure and skeletal development. Does not have guanylate cyclase activity. NPR3 Protein, Human, Recombinant (His) is expressed in E. coli expression system with N-... |
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TMPH-03250
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NPR3 Protein, Rat, Recombinant (His & SUMO)
Npr3,Atrial natriuretic peptide receptor 3,Atrial natriureti...
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Rat
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E. coli
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Receptor for the natriuretic peptide hormones, binding with similar affinities atrial natriuretic peptide NPPA/ANP, brain natriuretic peptide NPPB/BNP, and C-type natriuretic peptide NPPC/CNP. May function as a clearance receptor for NPPA, NPPB and NPPC, regulating their local concentrations and effects. May regulate diuresis, blood pressure and skeletal development. Does not have guanylate cyclase activity. NPR3 Protein, Rat, Recombinant (His & SUMO) is expressed in E. coli expression system wi... |
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TMPJ-00327
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M-CSF/CSF1 Protein, Human, Recombinant (His)
Lanimostim,M-CSF,CSF-1,MCSF,CSF1,集落刺激因子,Macrophage Colony-St...
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Human
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HEK293 Cells
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Macrophage Colony-Stimulating Factors (m-csf) are cytokines that act in hematopoiesis by controlling the production, differentiation, and function of 2 related white cell populations of the blood, the granulocytes and themonocytes-macrophages. CSF-1 promotes the release of proinflammatory chemokines, and thereby plays an important role in innate immunity and in inflammatory processes. It also plays an important role in the regulation of osteoclast proliferation and differentiation, the regulatio... |
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TMPJ-01218
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M-CSF/CSF1 Protein, Rat, Recombinant
CSF1,集落刺激因子,CSF-1,Macrophage colony-stimulating factor 1,M-C...
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Rat
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HEK293 Cells
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Rat Macrophage colony-stimulating factor 1(MCSF,CSF1) is a single-pass type I membrane cytokine. It is a hematopoietic growth factor that plays an essential role in the regulation of survival, proliferation and differentiation of hematopoietic precursor cells, especially mononuclear phagocytes, such as macrophages and monocytes. MCSF promotes the release of proinflammatory chemokines, and thereby plays an important role in innate immunity and in inflammatory processes. It is involved in the regu... |
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TMPH-03033
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P200 Protein, Mycoplasma pneumoniae, Recombinant (His & Myc)
p200,Protein P200
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Mycoplasma pneumoniae
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E. coli
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Protein cytoskeleton-associated which plays a role in gliding motility and perhaps also in mucociliary clearance. |
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TMPH-01612
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LSR Protein, Human, Recombinant (His)
Lipolysis-stimulated lipoprotein receptor,Angulin-1,LSR
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Human
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E. coli
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Probable role in the clearance of triglyceride-rich lipoprotein from blood. Binds chylomicrons, LDL and VLDL in presence of free fatty acids and allows their subsequent uptake in the cells. |
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TMPK-01416
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HLA-B*15:01&B2M&SARS-CoV-2 epitope (NQKLIANQF) Monomer Protein, Human, MHC (His & Avi), Biotinylated
MHC,SARS-CoV-2 epitope
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Human
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HEK293 Cells
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HLA-B*15:01 is strongly associated with asymptomatic infection with SARS-CoV-2 and is likely to be involved in the mechanism underlying early viral clearance. T cells from pre-pandemic individuals carrying HLA-B*15:01 were reactive to the immunodominant SARS-CoV-2 S-derived peptide NQKLIANQF, and 100% of the reactive cells displayed memory phenotype. |
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TMPJ-00981
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PTX3 Protein, Mouse, Recombinant (His)
alpha-induced protein 5,pentraxin 3, long,pentaxin-related g...
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Mouse
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HEK293 Cells
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Pentraxin-related protein PTX3, also known as Tumor necrosis factor-inducible gene 14 protein (TSG-14), belongs to the pentraxin family. PTX3 plays a role in the regulation of innate resistance to pathogens, inflammatory reactions, possibly clearance of self-components and female fertility. It’s subunit is a disulfide-linked homooctamer that binds to C1q. PTX3 concentration is elevated in the joint fluid of patients with rheumatoid arthritis (RA), indicating that PTX3 may be a potential mediator... |
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TMPK-01242
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MD2/LY96 Protein, Human, Recombinant (His)
MD-2,Ly-96,ESOP-1,Lymphocyte antigen 96,LY96,ESOP1
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Human
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E. coli
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MD2, a 160-residue accessory glycoprotein, is responsible for the recognition and binding of Gram-negative bacterial membrane component, lipopolysaccharide (LPS).Internalization of pathogen inside the mononuclear phagocytes has also been attributed to MD2 which leads to the clearance of pathogens from the host. MD2/LY96 Protein, Human, Recombinant (His) is expressed in E. coli expression system with C-His tag. The predicted molecular weight is 18.07 kDa and the accession number is Q9Y6Y9-1. |
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TMPJ-01233
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AGR3 Protein, Mouse, Recombinant (His)
AGR3,Anterior gradient protein 3,BCMP11,AG3
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Mouse
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HEK293 Cells
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Anterior gradient protein 3 (AGR3) is an 18 kDa member of the AGR family of proteins. It is expressed in the ciliated cells of the airway epithelium, not detected in the mucous cells. Mature human AGR3 shares 92% amino acid sequence identity with mouse AGR3. It is required for calcium-mediated regulation of ciliary beat frequency and mucociliary clearance in the airway. AGR3 might be involved in the regulation of intracellular calcium in tracheal epithelial cells. |
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TMPK-01412
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HLA-B*15:01&B2M&SARS-CoV-2 epitope (NQKLIANQF) Monomer Protein, Human, MHC (His & Avi)
SARS-CoV-2 epitope,MHC
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Human
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HEK293 Cells
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HLA-B*15:01 is strongly associated with asymptomatic infection with SARS-CoV-2 and is likely to be involved in the mechanism underlying early viral clearance. T cells from pre-pandemic individuals carrying HLA-B*15:01 were reactive to the immunodominant SARS-CoV-2 S-derived peptide NQKLIANQF, and 100% of the reactive cells displayed memory phenotype. |
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TMPH-02605
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Complement C4-B Protein, Mouse, Recombinant (His)
C3 and PZP-like alpha-2-macroglobulin domain-containing prot...
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Mouse
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E. coli
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Non-enzymatic component of C3 and C5 convertases and thus essential for the propagation of the classical complement pathway. Covalently binds to immunoglobulins and immune complexes and enhances the solubilization of immune aggregates and the clearance of IC through CR1 on erythrocytes. Catalyzes the transacylation of the thioester carbonyl group to form ester bonds with carbohydrate antigens. |
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TMPH-00208
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Serotype 3 fimbrial subunit Protein, Bordetella pertussis, Recombinant (His)
fim3,Serotype 3 fimbrial subunit
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Bordetella pertussis
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E. coli
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Bordetella pertussis is the causative agent of whooping cough. An essential step in the disease process is the attachment of the bacteria to the ciliated epithelium of the respiratory tract, enabling the organism to resist normal host-clearance mechanisms. It is unclear which bacterial cell surface component are responsible for adherence but the fimbriae of B.pertussis are prime candidates for being involved in this process. Serotype 3 fimbrial subunit Protein, Bordetella pertussis, Recombinant ... |
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TMPK-00632
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MD2/LY96 Protein, Cynomolgus, Recombinant (His)
ESOP-1,LY96,Lymphocyte antigen 96,ESOP1,MD-2
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Cynomolgus
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E. coli
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MD2, a 160-residue accessory glycoprotein, is responsible for the recognition and binding of Gram-negative bacterial membrane component, lipopolysaccharide (LPS).Internalization of pathogen inside the mononuclear phagocytes has also been attributed to MD2 which leads to the clearance of pathogens from the host. MD2/LY96 Protein, Cynomolgus, Recombinant (His) is expressed in E. coli expression system with C-His tag. The predicted molecular weight is 17.97 kDa and the accession number is B3Y6B0. |
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TMPJ-00875
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NPPB Protein, Human, Recombinant (His)
NPPB,γ-Brain Natriuretic Peptide,Gamma-Brain Natriuretic Pep...
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Human
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E. coli
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Human Natriuretic peptides B acts as a cardiac hormone; it is associated with many biological actions, such as diuresis, natriuresis, vasorelaxation, which inhibits the secretion of rennin and aldosterone. It acts as a paracrine antifibrotic factor in the heart. Natriuretic peptides B can help restore the body balance of salt and water, improves the heart function. Natriuretic peptides B binds and stimulates the cGMP production of the NPR1 receptor and binds the clearance receptor NPR3. |
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TMPK-00799
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ANXA1 Protein, Mouse, Recombinant (His)
Calpactin-2,LPC1,Annexin-1,Annexin I,ANXA1,p35,Chromobindin-...
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Mouse
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E. coli
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Atherosclerosis, characterized by the formation of fat-laden plaques, is a chronic inflammatory disease. ABCA1 promotes cholesterol efflux, reduces cellular cholesterol accumulation, and regulates anti-inflammatory activities in an apoA-I- or ANXA1-dependent manner. The latter activity occurs by mediating the efflux of ANXA1, which plays a critical role in anti-inflammatory effects, cholesterol transport, exosome and microparticle secretion, and apoptotic cell clearance. ANXA1 Protein, Mouse, Re... |
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TMPY-04205
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AGR3 Protein, Human, Recombinant (mFc)
hAG-3,AG3,HAG3,anterior gradient 3,PDIA18,BCMP11,AG-3
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Human
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HEK293 Cells
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Anterior gradient protein (AGR) 3 is a highly related homologue of pro-oncogenic AGR2 and belongs to the family of protein disulfide isomerases. AGR3 was found in breast, ovary, prostate, and liver cancer, it is associated with the level of differentiation, slowly proliferating tumors, and more favorable prognosis of breast cancer patients. AGR3 is a specialized member of the PDI family that plays an unexpected role in the regulation of CBF and mucociliary clearance in the airway. AGR3 had been... |
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TMPK-01291
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ANXA1 Protein, Cynomolgus, Recombinant (His)
Lipocortin I,Calpactin-2,ANX1,ANXA1,Annexin A1,Annexin I,LPC...
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Cynomolgus
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E. coli
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Atherosclerosis, characterized by the formation of fat-laden plaques, is a chronic inflammatory disease. ABCA1 promotes cholesterol efflux, reduces cellular cholesterol accumulation, and regulates anti-inflammatory activities in an apoA-I- or ANXA1-dependent manner. The latter activity occurs by mediating the efflux of ANXA1, which plays a critical role in anti-inflammatory effects, cholesterol transport, exosome and microparticle secretion, and apoptotic cell clearance. ANXA1 Protein, Cynomolgu... |
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TMPK-00768
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ANXA1 Protein, Human, Recombinant (His)
Annexin A1,Calpactin II,ANX1,p35,Lipocortin I,ANXA1,Calpacti...
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Human
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E. coli
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Atherosclerosis, characterized by the formation of fat-laden plaques, is a chronic inflammatory disease. ABCA1 promotes cholesterol efflux, reduces cellular cholesterol accumulation, and regulates anti-inflammatory activities in an apoA-I- or ANXA1-dependent manner. The latter activity occurs by mediating the efflux of ANXA1, which plays a critical role in anti-inflammatory effects, cholesterol transport, exosome and microparticle secretion, and apoptotic cell clearance. ANXA1 Protein, Human, Re... |
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TMPH-03574
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SdrE Protein, S. aureus, Recombinant (His)
sdrE,Serine-aspartate repeat-containing protein E
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Staphylococcus aureus
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E. coli
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Cell surface-associated calcium-binding protein which plays an important role in adhesion and pathogenesis. Contributes to the resistance to killing by innate immune components in blood and thus attenuates bacterial clearance by interacting with host complement factor H/CFAH and modulating its activity. Inhibits also bacterial opsonization and killing by interacting with host complement regulator C4BPA and thus inhibiting classical complement pathway activation. SdrE Protein, S. aureus, Recombin... |
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TMPH-02974
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Von Willebrand Factor/vWF Protein, Mouse, Recombinant (His & Myc)
Vwf,von Willebrand factor
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Mouse
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E. coli
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Important in the maintenance of hemostasis, it promotes adhesion of platelets to the sites of vascular injury by forming a molecular bridge between sub-endothelial collagen matrix and platelet-surface receptor complex GPIb-IX-V. Also acts as a chaperone for coagulation factor VIII, delivering it to the site of injury, stabilizing its heterodimeric structure and protecting it from premature clearance from plasma. Von Willebrand Factor/vWF Protein, Mouse, Recombinant (His & Myc) is expressed in E.... |
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TMPJ-00878
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NPR3 Protein, Human, Recombinant (hFc)
ANPRC,ANPR-C,C5orf23,NPR-C,NPRC,NPR3,ANP-C
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Human
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HEK293 Cells
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Atrial Natriuretic Peptide Receptor-3 (NPR3), also known as NPRC or ANPR-C, is one of the three natriuretic peptide receptors, is a type I transmembrane glycoprotein. The natriuretic system is key to the maintenance of vascular tone and cardiovascular homeostasis. Receptor for the natriuretic peptide hormones, binding with similar affinities atrial natriuretic peptide NPPA/ANP, brain natriuretic peptide NPPB/BNP, and C-type natriuretic peptide NPPC/CNP. May function as a clearance receptor for N... |
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TMPH-01729
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Myosin-9/MYH9 Protein, Human, Recombinant (GST)
Myosin-9,MYH9,Myosin heavy chain 9,Myosin heavy chain, non-m...
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Human
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E. coli
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Cellular myosin that appears to play a role in cytokinesis, cell shape, and specialized functions such as secretion and capping. Required for cortical actin clearance prior to oocyte exocytosis. Promotes cell motility in conjunction with S100A4. During cell spreading, plays an important role in cytoskeleton reorganization, focal contact formation (in the margins but not the central part of spreading cells), and lamellipodial retraction; this function is mechanically antagonized by MYH10. Myosin-... |
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TMPJ-00851
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IDE Protein, Human, Recombinant (His)
Insulysin,Insulinase,Insulin-Degrading Enzyme,IDE,Abeta-Degr...
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Human
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HEK293 Cells
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Insulin-Degrading Enzyme (IDE) is a secreted enzyme that belongs to the peptidase M16 family. IDE is a large zinc-binding protease and cleaves multiple short polypeptides that vary considerably in sequence. IDE plays a role in the cellular breakdown of insulin, IAPP, glucagon, bradykinin, kallidin, and other peptides, and thereby plays a role in intercellular peptide signaling. IDE degrades amyloid formed by APP and IAPP. IDE may participate in the degradation and clearance of naturally secreted... |
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TMPJ-01283
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UGRP1 Protein, Human, Recombinant
Uteroglobin-Related Protein 1,Secretoglobin Family 3A Member...
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Human
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E. coli
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Uteroglobin-Related Protein 1 (UGRP1) belongs to the secretoglobin family which has been suggested to play a role in lung inflammation and allergic diseases. UGRP1 is a 17 kDa secreted homodimeric protein that shows amino acid sequence similarity with uteroglobin. UGRP1 is expressed predominantly in the lung and low levels of expression are detected in the thyroid. Expression of UGRP1 in lung epithelial cells is enhanced by IL-10 and decreased through the activities of IL-9 and IL-5. UGRP1 inter... |
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TMPJ-01143
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MERTK/Mer Protein, Human, Recombinant (aa 1-323, His)
MER,Receptor tyrosine kinase MerTK,Tyrosine-protein kinase M...
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Human
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HEK293 Cells
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Tyrosine-protein kinase Mer (MERTK) is a single-pass type I membrane protein which belongs to the MER/AXL/TYRO3 receptor kinase family. MERTK include two fibronectin type-III domains, two Ig-like C2-type domains, and one tyrosine kinase domain. It can’t be expressed in normal B- and T-lymphocytes, but it is usually expressed in numerous neoplastic B- and T-cell lines. MERTK could regulate many physiological processes, such as cell survival, migration, differentiation. It was demonstrated that t... |
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TMPJ-00353
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ILDR2 Protein, Human, Recombinant (His)
Angulin-3,immunoglobulin-like domain containing receptor 2,D...
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Human
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HEK293 Cells
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ILDR2 is a member of the B7-like family of proteins that regulate T cell activity, is also a known endoplasmic reticulum molecule that regulates lipid homeostasis. The human ILDR2 lumenal domain shares a 99% and 98% homology with the mouse and rat respectively. The human gene encoding ILDR2 is located in a region on Chr1q23–25 that has been associated with type 2 diabetes. ILDR2 plays critical roles in hepatic clearance of lipoproteins and in lipid homeostasis. ILDR2 regulates human dendritic ce... |
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TMPY-01816
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Pentraxin 3 Protein, Human, Recombinant (His)
TNFAIP5,pentraxin 3,PTX3,TSG-14
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Human
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HEK293 Cells
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Pentraxin-related protein PTX3, also known as Tumor necrosis factor alpha-induced protein 5, Tumor necrosis factor-inducible gene 14 protein, TSG-14, PTX3 and TNFAIP5, is a secreted protein that contains one pentaxin domain. PTX3 plays a role in the regulation of innate resistance to pathogens, inflammatory reactions, possibly clearance of self-components and female fertility. Pentraxins are a family of evolutionarily conserved multifunctional pattern-recognition proteins characterized by a cycl... |
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TMPY-02063
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Alpha-2-macroglobulin Protein, Human, Recombinant (His)
α-2-macroglobulin,FWP007,CPAMD5,A2MD,S863-7,alpha-2-macroglo...
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Human
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Baculovirus Insect Cells
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alpha-2-macroglobulin, also known as α2-macroglobulin (α2M and A2M), is an abundant protein of the plasma of vertebrates and members of several invertebrate phyla and functions as a broad-spectrum protease-binding protein. alpha-2-macroglobulin is produced by the liver, and is a major component of the alpha-2 band in protein electrophoresis. alpha-2-macroglobulin is a large plasma glycoprotein that has long been known as an irreversible inhibitor of a variety of proteinases. More recently, it ha... |
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TMPH-02690
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PLA2G10 Protein, Mouse, Recombinant (His & Myc)
Pla2g10,Group X secretory phospholipase A2,Phosphatidylcholi...
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Mouse
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E. coli
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Secretory calcium-dependent phospholipase A2 that primarily targets extracellular phospholipids. Hydrolyzes the ester bond of the fatty acyl group attached at sn-2 position of phospholipids with preference for phosphatidylcholines and phosphatidylglycerols over phosphatidylethanolamines. Preferentially releases sn-2 omega-6 and omega-3 polyunsaturated fatty acyl (PUFA) chains over saturated fatty acyls. Contributes to phospholipid remodeling of very low-density lipoprotein (VLDL), low-density li... |
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