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Search Results for " chemoprevention "

Targets Recommended: Others

2

抑制剂 & 化合物

5

天然产物

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Cat. No.	Product Name	Target	Signaling Pathways
T39443	4′-Bromoflavone	Others	Others
	4′-Bromoflavone is a highly effective inducer of phase II detoxification enzymes and has been identified as a potent agent in cancer chemoprevention.
T69269	DMGF	Others	Others
	DMGF, also known as 7,7-dimethoxyagastisfavone, is a biflavonoid isolated from Taxus × media cv. Hicksii. DMGF induces apoptotic and autophagic cell death. DMGF could effectively attenuate the motility of B16F10 cells, and the results of real-time PCR revealed that DMGF also suppressed the expressions of matrix metalloproteinase-2 (MMP-2). MGF can inhibit the metastasis of highly invasive melanoma cancer cells through the down-regulation of F-actin polymerization DMGF may be further developed to...

化合物

4′-Bromoflavone

Cat.No: T39443

Target: Others

Cat.No: T69269

Target: Others

Cat. No.	Product Name	Target	Signaling Pathways
T4592	TOMATIDINE HYDROCHLORIDE Tomatidine,Tomatidine HCl,盐酸番茄碱	Others; NF-κB; JNK; Autophagy	Autophagy; MAPK; NF-κB; Others
	Tomatidine hydrochloride (Tomatidine HCl) 是一种甾体生物碱，可防止肌肉萎缩并促进肌肉生长。它通过阻断 NF-κB 和JNK 信号发挥抗炎作用，可激活哺乳动物细胞或秀丽隐杆线虫中的自噬。
TN4151	Glyurallin A	Others	Others
	Glyurallin A possesses an antigenotoxic effect against carcinogenic N-methyl-N-nitrosourea (MNU) for the first time, it is important to prevent DNA damage by N-nitrosamines for cancer chemoprevention.
TN2314	Xanthohumol D 黄腐醇 D	Others	Others
	Xanthohumol and xanthohumol D are potent inducers of quinone reductase, suggests that they could be used as chemoprevention agents.
TN6419	Chamaejasmine
	Chamaejasmine could be a candidate drug for osteosarcoma and breast cancer chemoprevention, induces apoptosis in MG63 and HEp-2 cells by Akt inactivation and dephosphorylation of BAD. It inhibits Bcl-2 expression and induces Bax expression to desintegrate
TN1498	Cimigenol	Others	Others
	Cimigenol is a potential antitumor compound, combination of it with an autophagy inhibitor may be a valuable strategy for the chemoprevention or treatment of colon cancer. It exerted potent cytotoxic activity against SMMC-7721 (7.87μM) and A-549 (12.16 μM

天然产物

TOMATIDINE HYDROCHLORIDE

Cat.No: T4592

Synonym: Tomatidine,Tomatidine HCl,盐酸番茄碱

Target: Others, NF-κB, JNK, Autophagy

Cat.No: TN4151

Target: Others

Cat.No: TN2314

Synonym: 黄腐醇 D

Target: Others

Cat.No: TN6419

Cat.No: TN1498

Target: Others

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