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Search Results for " bone morphogenetic proteins (bmps) "
Targets Recommended: ALK TGF-beta/Smad

1

抑制剂 & 化合物

3

重组蛋白

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Cat. No. Product Name Target Signaling Pathways
T1944 LDN-214117

ALK; TGF-beta/Smad Angiogenesis; Stem Cells; Tyrosine Kinase/Adaptors
LDN214117 是一种高效的 ALK2 选择性抑制剂(IC50:22nM),也是一种 BMP6 抑制剂(IC50:100nM),对ALK5抑制力弱100倍。

化合物

LDN-214117
Cat.No: T1944
Synonym:
Target: ALK, TGF-beta/Smad
Cat. No. Product Name Species Expression System
TMPJ-01065 Noggin/NOG Protein, Mouse, Recombinant (His)

Nog,Noggin

Mouse HEK293 Cells
Noggin is a secreted homodimeric glycoprotein that is an antagonist of bone morphogenetic proteins (BMPs). Mouse Noggin cDNA encodes a 232 amino acid (aa) residue precursor protein with 19 aa residue putative signal peptide that is cleaved to generate the 213 aa residue mature protein which is secreted as a homodimeric glycoprotein. Secreted Noggin probably remains close to the cell surface due to its binding of heparin-containing proteoglycans. Noggin binds some BMPs such as BMP4 with high affi...
TMPY-01817 GDF-10 Protein, Mouse, Recombinant (hFc)

growth differentiation factor 10,Bmp3b

Mouse HEK293 Cells
BMP-3b / GDF-10 is a member of the bone morphogenetic protein (BMP) family and the TGF-beta superfamily. This group of proteins is characterized by a polybasic proteolytic processing site which is cleaved to produce a mature protein containing seven conserved cysteine residues. The members of this family are regulators of cell growth and differentiation in both embryonic and adult tissues. Studies in mice suggest that the protein encoded by this gene plays a role in skeletal morphogenesis. In th...
TMPY-00681 BMP-5 Protein, Human, Recombinant (hFc)

bone morphogenetic protein 5

Human HEK293 Cells
Bone Morphogenetic Protein 5 (BMP-5) is a member of the structurally and functionally related bone morphogenetic proteins (BMPs) which constitute a novel subfamily of the transforming growth factor β (TGF-β) superfamily. In agreement with a possible role in the control of cell death, BMP-5 exhibited a regulated pattern of expression in the interdigital tissue. Transcripts of BMP-5 and BMP-5 protein were abundant within the cytoplasm of the fragmenting apoptotic interdigital cells in a way sugges...

重组蛋白

Noggin/NOG Protein, Mouse, Recombinant (His)
Cat.No: TMPJ-01065
Species: Mouse
Expression System: HEK293 Cells
GDF-10 Protein, Mouse, Recombinant (hFc)
Cat.No: TMPY-01817
Species: Mouse
Expression System: HEK293 Cells
BMP-5 Protein, Human, Recombinant (hFc)
Cat.No: TMPY-00681
Species: Human
Expression System: HEK293 Cells
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