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Search Results for " anticoagulant "

Targets Recommended: Thrombin

72

抑制剂 & 化合物

18

天然产物

1

化合物库

13

重组蛋白

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Cat. No.	Product Name
L7500	凝血与抗凝化合物库		144 compounds
	144 个化合物的独特集合，可用于高通量筛选和高内涵筛选；

化合物库

凝血与抗凝化合物库

Cat.No: L7500

Compounds: 144

Cat. No.	Product Name	Target	Signaling Pathways
T5519	Bivalirudin BG-8967,比伐卢定,Hirulog-1	Thrombin	Proteases/Proteasome
	Bivalirudin (BG-8967) 是一种直接凝血酶(thrombin)抑制剂，是一种肽类抗凝剂，可在侵入性心脏病，特别是在经皮冠状动脉介入中用于抗凝。
T20470	Edetic acid Ethylenediaminetetraacetic acid,乙二胺四乙酸,EDTA	Others	Others
	Edetic acid (Ethylenediaminetetraacetic acid) 是 Edetate 的酸形式，是一种具有抗高钙血症和抗凝血特性的螯合剂。它与钙和重金属离子结合后，会形成可溶的稳定复合体，使血清钙水平降低。它也可用作血液样本的抗凝剂，并用于治疗铅中毒。
T31206	Darexaban YM 150,Darexaban, Tanexaban,YM150	Factor Xa	Metabolism
	Darexaban (Tanexaban, YM-150) 是选择性的、口服具有活力的 Xa 因子 (FXa) 抑制剂，IC50=54.6 nM。它对其他相关丝氨酸蛋白酶(如胰蛋白酶、凝血酶和激肽释放酶)具有高选择性。它具有抗凝和抗血栓形成作用。
T0389	Dabigatran etexilate 达比加群酯,BIBR 1048	Thrombin	Proteases/Proteasome
	Dabigatran etexilate (BIBR 1048) 是一种 Dabigatran 前药，具有口服活性。它具有抗凝作用，能够预防心房颤动引起的静脉血栓栓塞和中风。
T5133	Dabigatran Etexilate Mesylate 甲磺酸达比加群酯,BIBR 1048MS,Dabigatran etexilate methanesulfonate	Thrombin	Proteases/Proteasome
	Dabigatran Etexilate Mesylate (BIBR 1048MS) 是一种口服具有活性的 Dabigatran 前药，具有抗凝作用，能够预防心房颤动引起的静脉血栓栓塞和中风。
T2368	Edoxaban Tosylate Monohydrate DU-176b,DU-176b tosylate Monohydrate,Lixiana,Edoxaban,依度沙班对甲苯磺酸盐一水化合物	Factor Xa; Thrombin	Metabolism; Proteases/Proteasome
	Edoxaban Tosylate Monohydrate (DU-176b tosylate Monohydrate) 是口服具有活力的 factor Xa 选择性抑制剂。它是一种抗凝剂，可用于预防中风，是一种凝血酶和凝血因子 IXaβ (FIXa) 的弱抑制剂，对 FXa 的选择性超过 10000 倍。它具有抗血栓形成的特性，可用于血栓栓塞性疾病的研究。
T1515	Bromindione 溴茚二酮,溴茚二酮(INN),Fluidane,Halinone	Others	Others
	Bromindione (Fluidane) 是强效且长效的 Inandione 衍生口服抗凝化合物。
T0360	Chlorindione chlophenadione,Indaliton,氯苯茚二酮,G-25766	Others	Others
	Chlorindione (chlophenadione) 是一种维生素 K1 的拮抗剂，也是一种有效的抗凝剂。
TP1628L	Activated Protein C (390-404), human acetate Activated Protein C (390-404), human acetate(146340-20-7 Free base)	APC	Cell Cycle/Checkpoint
	Activated Protein C (390-404), human acetate (Activated Protein C ) 抑制 APC 抗凝活性。
T9153	Picotamide	Others	Others
	Picotamide 具有抗凝和纤维蛋白溶解特性。
T30191L	Atecegatran TFA Atecegatran TFA(917904-13-3 Free base）,AR-H067637 TFA	Others	Others
	Atecegatran TFA 常被当作一种抗凝血剂，可用来治疗心血管疾病。
T0155	Argatroban MCI-9038,阿加曲班,MD-805,Argipidine	Thrombin	Proteases/Proteasome
	Argatroban (MCI-9038) 是一种选择性的凝血酶抑制剂。
T22246	Argatroban Monohydrate 阿加曲班一水合物,阿加曲班	Thrombin	Proteases/Proteasome
	Argatroban Monohydrate 是一种 thrombin 选择性抑制剂。
T77690	L-Cyclohexylalanine L-3-Cyclohexylalanine,H-Cha-OH,3-Cyclohexyl-L-alanine
	L-Cyclohexylalanine (L-3-Cyclohexylalanine) 是一种氨基酸类似物，与短杆菌肽S合成酶的重酶硫酯结合。L-Cyclohexylalanine 可用来合成抗凝血十肽。
T80792	WAY-639228	Others	Others
	WAY-639228-A 具有潜在的抗血栓和抗凝活性，可用于研究脑血栓。
T50001	Tinoridine ethyl 2-amino-6-benzyl-4H,5H,6H,7H-thieno[2,3-c]pyridine-3-carboxylate,替诺立定	P450	Metabolism
	Tinoridine 通过抑制环氧合酶-2（COX-2）的产生来发挥作用，具有抗炎、抗过敏和抗凝血等活性。
T0372	Gabexate mesylate 甲磺酸加贝酯,FOY	Factor Xa; Serine Protease; Proteasome	Metabolism; Proteases/Proteasome; Ubiquitination
	Gabexate mesylate (FOY) 是一种非抗原的类胰蛋白酶丝氨酸蛋白酶抑制剂。
T26240	Surfen dihydrochloride Aminokinuride dihydrochloride,Aminoquinuride dihydrochloride,NSC-12155,Aminokinuride 2HCl,Aminoquinuride 2HCl	FGFR; Antiviral; Antibiotic	Angiogenesis; Immunology/Inflammation; Microbiology/Virology; Tyrosine Kinase/Adaptors
	Surfen dihydrochloride (Aminoquinuride dihydrochloride) 是一种有效的硫酸肝素小分子拮抗剂，具有抗菌和抗病毒活性，抑制炭疽致死因子、凝血因子 X 和致死因子。Surfen dihydrochloride 可抑制普通肝素和低分子量肝素的抗凝活性，抑制肝素的硫酸化和肝素裂解酶的降解。Surfen dihydrochloridn 抑制阻断硫酸乙酰肝素介导的 FGF2 结合和信号转导。Surfen 抑制 SEVI 和精液介导的 HIV 1 型感染增强。
T0514	Phenindione Rectadione,phenylindandione,苯茚二酮,Phenylindione	Others	Others
	Phenindione (Rectadione) 是一种茚满二酮，已被用作抗凝剂，可作为维生素 K 拮抗剂。它的作用类似于华法林，但由于其严重不良反应的发生率较高，现在很少使用。
T6531	Heparin sodium salt 肝素钠,Sodium heparinate,Heparin sodium	Factor Xa; Thrombin; Autophagy	Autophagy; Metabolism; Proteases/Proteasome
	Heparin sodium salt (Sodium heparinate) 是一种抗凝血剂，可以干扰血凝过程中的多个环节。Heparin sodium salt 可以与抗凝血酶 III 可逆结合，加快凝血酶因子 IIa 和 Xa 的失活速度，从而发挥抗凝作用。
T1736	Apixaban 阿哌沙班,BMS-562247-01	Factor Xa	Metabolism
	Apixaban (BMS-562247-01) 是一种高度选择性，可逆的、口服具有活力的凝血因子 Xa (Factor Xa) 抑制剂，抑制人和兔凝血因子 Xa 的 Ki 分别为 0.08 nM 和 0.17 nM。它可以用于研究各种血栓栓塞疾病。
T4980	Betrixaban maleate	Factor Xa	Metabolism
	Betrixaban maleate 是一种非维生素 K 口服抗凝剂，其作用是由 Xa 因子的竞争性和可逆抑制作用驱动的。
T10820L1	Ciraparantag acetate Ciraparantag acetate(1438492-26-2 Free base)	Others	Others
	Ciraparantag acetate 是一种抗凝逆转剂，是一种小分子，专门设计用于通过电荷-电荷相互作用与普通肝素和低分子量肝素非共价结合。它显示出与直接口服抗凝剂 (DOAC) 相似的结合特性。
T1184	Rivaroxaban BAY 59-7939,利伐沙班	Factor Xa; Thrombin	Metabolism; Proteases/Proteasome
	Rivaroxaban (BAY 59-7939) 是高效选择性的凝血因子 Xa (FXa) 直接抑制剂，IC50=0.7 nM，Ki 为 0.4 nM。
T77124	Osocimab BAY 1213790	FXR	Metabolism
	Osocimab (BAY 1213790) 是一种高效的抗 FXIa 抗体，Ki 值为 2.4 nM，EC50 值为 0.2 nM。Osocimab 可能通过 FXI 抑制降低血栓形成。Osocimab 常被当作 XI 因子抑制剂，对凝血酶生成有抑制作用，有抗凝血作用，可用于研究血栓栓塞性疾病。
T4341	Betrixaban 贝曲西班,PRT054021	Factor Xa	Metabolism
	Betrixaban (PRT054021) 是一种口服具有活力的选择性factor Xa(fXa) 抑制剂，IC50=1.5 nM。
T0815L	Warfarin sodium	Others	Others
	Warfarin sodium 是一种抗凝血剂，通过抑制维生素 K 依赖性凝血因子的合成起作用。华法林适用于预防和/或治疗静脉血栓形成及其延伸、肺栓塞和房颤栓塞。它还用作预防心肌梗塞后全身性栓塞的辅助剂。华法林也用作杀鼠剂。
T2368L	Edoxaban Lixiana,依杜沙班	Factor Xa; Thrombin	Metabolism; Proteases/Proteasome
	Edoxaban (Lixiana) (DU-176) 是一种选择性的，口服有效的 factor Xa (FXa)抑制剂。Edoxaban 对游离 FXa 和凝血酶原的 Ki 分别为 0.561 nM 和 2.98 nM。Edoxaban 是一种抗凝剂，可用于预防中风。Edoxaban 还是一种凝血酶和凝血因子 IXaβ (FIXa) 的弱抑制剂，Ki 值分别为 6.00 μM 和 41.7 μM，对 FXa 的选择性超过 10000 倍。由于具有抗血栓形成的特性，Edoxaban 可用于预防血栓栓塞性疾病的研究。
T24930	Valone AI300366,AI3-00366,AI3 00366	Others	Others
	Valone is an anticoagulant.
T28404	Phenyramidol Hydrochloride Vazalmin,Analexin,Firmalgil,Phenyramidol HCl,Betapirin	Others	Others
	Phenyramidol Hydrochloride is an anticoagulant and analgesic.
T27545	Hirugen BG 8865,Hirudin dodecapeptide	Others	Others
	Hirugen is a derivative of hirudin, which is an anticoagulant protein found in leeches.
T25835	Moxicoumone	Others	Others
	Moxicoumone is an anticoagulant agent.
T76561	Anpocogin
	Anpocogin 是 Ancyclostoma canium 线虫的抗凝蛋白 c2 变体（添加了 C 末端 P85）。Anpocogin 在Pichia pastoris 中产生，用作抗凝剂。
T25909	Oxazidione LD 4610,Transidione,LD4610,LD-4610,Amplidione	Others	Others
	Oxazidione 是一种抗凝血化合物，也是一种有用的医药中间体。
T20616	Coumachlor G-23133,Ratilan,G23133,Tomorin,G 23133	Others	Others
	Coumachlor, a first-generation anticoagulant rodenticide, blocks the formation of prothrombin and inhibits blood coagulation causing internal haemorrhage.
T30191	Atecegatran metabolite of AZD0837,atecegatran metoxil	Others	Others
	Atecegatran 常被当作一种抗凝血剂属于，可用来治疗心血管疾病。
T19708	(S)-Warfarin	Others	Others
	(S)-Warfarin is a more effective enantiomer of Warfarin. It is used as a vitamin K antagonist, with anticoagulant.
T62662	Tioclomarol	Others	Others
	Tioclomarol 是一种香豆素抗凝剂，维生素 K 拮抗剂。
TP1628	Activated Protein C (390-404), human
	Activated Protein C (390-404), human, a peptide derived from the vitamin K-dependent serine protease, effectively suppresses the anticoagulant activity of APC[1].
T23052	Nafamostat	Others	Others
	Nafamostat is a synthetic serine protease inhibitor and is an anticoagulant.
T23051	Nafamostat hydrochloride	Others	Others
	Nafamostat hydrochloride is a synthetic serine protease inhibitor and is an anticoagulant.
T23755	AS1468240 AS 1468240,AS-1468240	Others	Others
	AS1468240 is a factor Xa inhibitor. It has significant oral anticoagulant activity.
T23898	Clocoumarol Clocoumarolum,BRN 1264788,DB 112	Others	Others
	Clocoumarol is an anticoagulant that prevents blood clotting. It also can inhibit the dilatation of the spleen and the congestion of lymph nodes.
T70184	YM-60828 dihydrochloride	Others	Others
	YM-60828 dihydrochloride is a Factor Xa (FXa) inhibitor and anticoagulant used in the treatment of venous thromboembolic disease.
T71543	Difethialone	Others	Others
	Difethialone is an anticoagulant rodenticide and a vitamin K antagonist.
T71532	Fondaparinux free base	Others	Others
	Fondaparinux Free Base is a synthetic pentasaccharide that mediates the interaction of HEPARIN with ANTITHROMBINS and inhibits FACTOR Xa; it is used for prevention of VENOUS THROMBOEMBOLISM after surgery. Fondaparinux is a clinically approved anticoagulant pentasaccharide for the treatment of thrombotic diseases, displays better efficacy and biosafety than other heparin-based anticoagulant drugs.
T82197	Hirudin (54-65) (TFA)
	Hirudin (54-65) TFA，是一种具有抗凝血活性的Hirudin 65残基蛋白片段。
T71601	CU-2010	Others	Others
	CU-2010 is a synthetic serine protease inhibitor with antifibrinolytic and anticoagulant properties. CU-2010 dose-dependently reduces postoperative blood loss and improves postischemic recovery after cardiac surgery in a canine model.
T16377	Odiparcil SB-424323	Thrombin	Proteases/Proteasome
	Odiparcil is an orally active beta-d-thioxyloside analog. Odiparcil is an indirect thrombin inhibitor that exerts its anticoagulant effect through activation of antithrombin II (heparin cofactor II). It also has an antithrombotic activity associated with a reduced risk of adverse bleeding events.
T82521	D-Val-Leu-Lys-chloromethylketone
	D-Val-Leu-Lys-chloromethylketone，一种含D-Val、Leu和Lys三种氨基酸的多肽类化合物，具有抗凝血功能。

化合物

Cat.No: T5519

Synonym: BG-8967,比伐卢定,Hirulog-1

Target: Thrombin

Cat.No: T20470

Synonym: Ethylenediaminetetraacetic acid,乙二胺四乙酸,EDTA

Target: Others

Cat.No: T31206

Synonym: YM 150,Darexaban, Tanexaban,YM150

Target: Factor Xa

Dabigatran etexilate

Cat.No: T0389

Synonym: 达比加群酯,BIBR 1048

Target: Thrombin

Dabigatran Etexilate Mesylate

Cat.No: T5133

Synonym: 甲磺酸达比加群酯,BIBR 1048MS,Dabigatran etexilate methanesulfonate

Target: Thrombin

Edoxaban Tosylate Monohydrate

Cat.No: T2368

Synonym: DU-176b,DU-176b tosylate Monohydrate,Lixiana,Edoxaban,依度沙班对甲苯磺酸盐一水化合物

Target: Factor Xa, Thrombin

Cat.No: T1515

Synonym: 溴茚二酮,溴茚二酮(INN),Fluidane,Halinone

Target: Others

Cat.No: T0360

Synonym: chlophenadione,Indaliton,氯苯茚二酮,G-25766

Target: Others

Activated Protein C (390-404), human acetate

Cat.No: TP1628L

Synonym: Activated Protein C (390-404), human acetate(146340-20-7 Free base)

Target: APC

Cat.No: T9153

Target: Others

Atecegatran TFA

Cat.No: T30191L

Synonym: Atecegatran TFA(917904-13-3 Free base）,AR-H067637 TFA

Target: Others

Cat.No: T0155

Synonym: MCI-9038,阿加曲班,MD-805,Argipidine

Target: Thrombin

Argatroban Monohydrate

Cat.No: T22246

Synonym: 阿加曲班一水合物,阿加曲班

Target: Thrombin

L-Cyclohexylalanine

Cat.No: T77690

Synonym: L-3-Cyclohexylalanine,H-Cha-OH,3-Cyclohexyl-L-alanine

Cat.No: T80792

Target: Others

Cat.No: T50001

Synonym: ethyl 2-amino-6-benzyl-4H,5H,6H,7H-thieno[2,3-c]pyridine-3-carboxylate,替诺立定

Target: P450

Gabexate mesylate

Cat.No: T0372

Synonym: 甲磺酸加贝酯,FOY

Target: Factor Xa, Serine Protease, Proteasome

Surfen dihydrochloride

Cat.No: T26240

Synonym: Aminokinuride dihydrochloride,Aminoquinuride dihydrochloride,NSC-12155,Aminokinuride 2HCl,Aminoquinuride 2HCl

Target: FGFR, Antiviral, Antibiotic

Cat.No: T0514

Synonym: Rectadione,phenylindandione,苯茚二酮,Phenylindione

Target: Others

Heparin sodium salt

Cat.No: T6531

Synonym: 肝素钠,Sodium heparinate,Heparin sodium

Target: Factor Xa, Thrombin, Autophagy

Cat.No: T1736

Synonym: 阿哌沙班,BMS-562247-01

Target: Factor Xa

Betrixaban maleate

Cat.No: T4980

Target: Factor Xa

Ciraparantag acetate

Cat.No: T10820L1

Synonym: Ciraparantag acetate(1438492-26-2 Free base)

Target: Others

Cat.No: T1184

Synonym: BAY 59-7939,利伐沙班

Target: Factor Xa, Thrombin

Cat.No: T77124

Synonym: BAY 1213790

Target: FXR

Cat.No: T4341

Synonym: 贝曲西班,PRT054021

Target: Factor Xa

Warfarin sodium

Cat.No: T0815L

Target: Others

Cat.No: T2368L

Synonym: Lixiana,依杜沙班

Target: Factor Xa, Thrombin

Cat.No: T24930

Synonym: AI300366,AI3-00366,AI3 00366

Target: Others

Phenyramidol Hydrochloride

Cat.No: T28404

Synonym: Vazalmin,Analexin,Firmalgil,Phenyramidol HCl,Betapirin

Target: Others

Cat.No: T27545

Synonym: BG 8865,Hirudin dodecapeptide

Target: Others

Cat.No: T25835

Target: Others

Cat.No: T76561

Cat.No: T25909

Synonym: LD 4610,Transidione,LD4610,LD-4610,Amplidione

Target: Others

Cat.No: T20616

Synonym: G-23133,Ratilan,G23133,Tomorin,G 23133

Target: Others

Cat.No: T30191

Synonym: metabolite of AZD0837,atecegatran metoxil

Target: Others

Cat.No: T19708

Target: Others

Cat.No: T62662

Target: Others

Activated Protein C (390-404), human

Cat.No: TP1628

Cat.No: T23052

Target: Others

Nafamostat hydrochloride

Cat.No: T23051

Target: Others

Cat.No: T23755

Synonym: AS 1468240,AS-1468240

Target: Others

Cat.No: T23898

Synonym: Clocoumarolum,BRN 1264788,DB 112

Target: Others

YM-60828 dihydrochloride

Cat.No: T70184

Target: Others

Cat.No: T71543

Target: Others

Fondaparinux free base

Cat.No: T71532

Target: Others

Hirudin (54-65) (TFA)

Cat.No: T82197

Cat.No: T71601

Target: Others

Cat.No: T16377

Synonym: SB-424323

Target: Thrombin

D-Val-Leu-Lys-chloromethylketone

Cat.No: T82521

Cat. No.	Product Name	Target	Signaling Pathways
T7544	Fucoidan 岩藻多糖	Others	Others
	Fucoidan 是一种 α-淀粉酶和 α-葡萄糖苷酶的有效抑制剂，是一种生物特性多糖。它具有抗凝血，抗肿瘤，抗氧化和抗脂肪特性。
TQ0197	Acenocoumarol 醋硝香豆素,新抗凝
	Acenocoumarol 是一种抗凝血剂，与 Vitamin K 拮抗剂的功能相似。
TN6444	Cyclo(Tyr-Leu)	Antifungal	Microbiology/Virology
	Cyclo(Tyr-Leu) 是一种来自马齿苋 Portulaca oleracea Linn 的环状二肽，具有细胞毒性、抗真菌和抗凝血活性。
T14291	Anisindione	Others	Others
	Anisindione 是合成的抗凝血剂，对活性促凝因子II，VII，IX 和X 的形成具有抑制作用。
T12952	Sodium citrate dihydrate Citric acid trisodium salt dihydrate,Trisodium citrate dihydrate,二水合柠檬酸钠	Antibacterial	Microbiology/Virology
	Sodium citrate dihydrate (Trisodium citrate dihydrate) 是一种抗凝血剂，也用为缓冲剂和食品防腐剂。
T5725	Salvianolic acid B 丹酚酸B,lithospermic acid B,Dan Shen Suan B	Sirtuin; Autophagy	Autophagy; Chromatin/Epigenetic; DNA Damage/DNA Repair
	Salvianolic acid B (Dan Shen Suan B) 是一种来自丹参的天然产物，是一种抗氧化剂，具有水溶性。Salvianolic acid B 具有抗血小板聚集、抗凝和抗血栓作用，常用来研究微循环疾病。
T5795	Suberosin 软木花椒素	Others; NF-κB	NF-κB; Others
	Suberosin 可分离自Plumbago zeylanica 中，通过调节NF-AT 和NF-κB，抑制PHA-诱导的 PBMC 细胞增殖并捕获细胞周期G1过渡到 S 期，具有抗炎和抗血凝的活性。
TL0013	Heraclenin 独活内酯	Anti-infection; Immunology/Inflammation related	Immunology/Inflammation; Microbiology/Virology
	Heraclenin 是一种天然呋喃香豆素。它浓度依赖性的靶向激活的 T 细胞核因子 (NFAT) ，抑制人原代 T 细胞中 T 细胞受体介导的增殖。
T2727	Salvianolic acid B	Others	Others
	Salvianolic acid B (Dan Shen Suan B) 是一种来自丹参提取物的水溶性抗氧化剂，具有抗血小板聚集、抗凝和抗血栓作用。它常用来研究微循环疾病。
T41031	Protamine sulfate	Thrombin	Proteases/Proteasome
	Protamine sulfate是一种多阳离子肽类，作为一种抗肝素剂。该化合物能中和肝素的抗凝作用并增强脂质介导的基因转移。
T0809	Dicoumarol Dicumarol,双羟香豆素,双香豆素	Dehydrogenase; NADPH; PDK	Metabolism; PI3K/Akt/mTOR signaling
	Dicoumarol (Dicumarol) 是一种 NAD(P)H: 醌氧化还原酶 1 和PDK1的抑制剂，它们的IC50值分别为 0.37 和 19.42 μM。
T2939	Forskolin 毛喉素,Coleonol,Colforsin	FXR; Adenylyl cyclase; AChR; Autophagy	Autophagy; Metabolism; Neuroscience
	Forskolin (Coleonol) 属于天然产物，是一种腺苷酸环化酶激活剂 (EC50=0.5 μM)。Forskolin 可以增加 cAMP 水平，可以激活 PXR 和 FXR，也可以诱导细胞自噬。Forskolin 对心脏产生正性肌力作用，具有血小板抗凝集和降压作用。
TN6689	Cyclo(Tyr-Phe)
	Cyclo-(Phe-Tyr) shows anticoagulant activities.
TN7367	trans-Psoralenoside	Others	Others
	Trans-Psoralenoside exhibits hepatoprotective (liver-protective), nephroprotective (kidney-protective), antiulcer, and anticoagulant properties.
TN1197	19α-Hydroxyasiatic acid 23-羟基委陵菜酸,19 alpha-Hydroxyasiatic acid	Others	Others
	19 alpha-Hydroxyasiatic acid shows significant anticoagulant effect on the extrinsic pathway.
TN3716	Coumurrayin	Others	Others
	Coumurrayin may have anticoagulant activity.
T20654	Heparin Certoparin,Bemiparin,Dalteparin,Adomiparin	Thrombin; Endogenous Metabolite; Antibacterial; Autophagy	Autophagy; Metabolism; Microbiology/Virology; Proteases/Proteasome
	Heparin (Adomiparin) 是硫酸粘多糖，常在临床医学上当抗凝剂使用。Heparin 在体内实验中显示出部分抗炎活性。
TN5901	Cudratricusxanthone A
	Cudratricusxanthone A has potent anti-proliferative, antioxidative, and monoamine oxidase inhibitory effects, it also possesses anti-cancer activities and provide a basis for developing effective therapeutic agents to inhibit growth and metastasis of brea

天然产物

Cat.No: T7544

Synonym: 岩藻多糖

Target: Others

Cat.No: TQ0197

Synonym: 醋硝香豆素,新抗凝

Cat.No: TN6444

Target: Antifungal

Cat.No: T14291

Target: Others

Sodium citrate dihydrate

Cat.No: T12952

Synonym: Citric acid trisodium salt dihydrate,Trisodium citrate dihydrate,二水合柠檬酸钠

Target: Antibacterial

Salvianolic acid B

Cat.No: T5725

Synonym: 丹酚酸B,lithospermic acid B,Dan Shen Suan B

Target: Sirtuin, Autophagy

Cat.No: T5795

Synonym: 软木花椒素

Target: Others, NF-κB

Cat.No: TL0013

Synonym: 独活内酯

Target: Anti-infection, Immunology/Inflammation related

Salvianolic acid B

Cat.No: T2727

Target: Others

Protamine sulfate

Cat.No: T41031

Target: Thrombin

Cat.No: T0809

Synonym: Dicumarol,双羟香豆素,双香豆素

Target: Dehydrogenase, NADPH, PDK

Cat.No: T2939

Synonym: 毛喉素,Coleonol,Colforsin

Target: FXR, Adenylyl cyclase, AChR, Autophagy

Cat.No: TN6689

trans-Psoralenoside

Cat.No: TN7367

Target: Others

19α-Hydroxyasiatic acid

Cat.No: TN1197

Synonym: 23-羟基委陵菜酸,19 alpha-Hydroxyasiatic acid

Target: Others

Cat.No: TN3716

Target: Others

Cat.No: T20654

Synonym: Certoparin,Bemiparin,Dalteparin,Adomiparin

Target: Thrombin, Endogenous Metabolite, Antibacterial, Autophagy

Cudratricusxanthone A

Cat.No: TN5901

Species：

Expression System：

Tag：

Cat. No.	Product Name	Species	Expression System
TMPH-03070	TAP Protein, Ornithodoros moubata, Recombinant (His) Tick anticoagulant peptide	Ornithodoros moubata	P. pastoris (Yeast)
	TAP is a slow, tight-binding inhibitor of blood coagulation, specific for factor Xa.
TMPH-03071	TAP Protein, Ornithodoros moubata, Recombinant (His & Myc & SUMO) Tick anticoagulant peptide	Ornithodoros moubata	E. coli
	TAP is a slow, tight-binding inhibitor of blood coagulation, specific for factor Xa.
TMPJ-00844	ANXA8 Protein, Human, Recombinant Vascular Anticoagulant-β,Annexin-8,Annexin A8,VAC-B...	Human	E. coli
	Annexin A8 (ANXA8) belongs to a family of calcium-dependent membrane and phospholipid binding proteins. Annexin A8 contains 4 annexin repeats separated by linking sequences of variable lengths. A pair of annexin repeats may form one binding site for calcium and phospholipid. ANXA8 is preferentially expressed in acute promyelocytic leukemia (APL) cells, which suggests its participation in hematopoietic cell differentiation. In addition, ANXA8 is an anticoagulant protein that acts as an indirect i...
TMPJ-00840	ANXA3 Protein, Human, Recombinant Annexin III,Placental anticoagulant protein III,35-...	Human	E. coli
	Annexin A3（ANXA3）contains 4 annexin repeats and belongs to the annexin family. Members of this calcium-dependent phospholipid-binding protein family play a role in the regulation of cellular growth and in signal transduction pathways. It is abnormally expressed in fetuses of both IVF and ICSI, which may contribute to the increase risk of birth defects in these ART. ANXA3 is Inhibitor of phospholipase A2 and cleaves the cyclic bond of inositol 1,2-cyclic phosphate to form inositol 1-phosphate. ...
TMPH-00936	ANXA3 Protein, Human, Recombinant (His) Annexin-3,Annexin III,35-alpha calcimedin,Inositol 1,2-cycli...	Human	E. coli
	ANXA3 Protein, Human, Recombinant (His) is expressed in E. coli.
TMPJ-00799	ANXA2 Protein, Human, Recombinant ANXA2,Calpactin I Heavy Chain,ANX2,p36,LPC2D,PAP-IV,ANX2L4,C...	Human	E. coli
	Annexin A2 (ANXA2) is a member of the annexin family and has roles in the regulation of cellular growth and in signal transduction pathways. ANXA2 protein is associated with sickle cell osteonecrosis and the expression reduce of ANXA2 is associated with osteosarcoma metastases. ANXA2 functions as an autocrine factor, it can increases osteoclast formation and bone resorption. ANXA2 is involved in muscular dystrophies. In humans, the up-regulation of ANXA2 is related with colon adenocarcinoma cell...
TMPJ-01204	TPSAB1 Protein, Human, Recombinant (His) TPS1,tryptase alpha/beta 1,TPS2,tryptase α/β1,tryptase α/β 1...	Human	HEK293 Cells
	Tryptases are serine proteases with trypsin-like specificity. Together with chymases and Cathepsin G, tryptases are important players in mast cell mediation of inflammatory and allergic responses. Tryptase alpha/beta-1(TPSAB1), also known as mast cell protease 7 (MCPT7), it exhibits anticoagulant activity due to its ability to degrade fibrinogen in the presence of a diverse array of protease inhibitors in plasma. The two Isoform 1 and isoform 2 are expressed in lung, stomach, spleen, heart and s...
TMPH-00938	ANXA5 Protein, Human, Recombinant (His) ANXA5,Annexin A5,Annexin V,Calphobindin I (CPB-I),ENX2,Endon...	Human	P. pastoris (Yeast)
	This protein is an anticoagulant protein that acts as an indirect inhibitor of the thromboplastin-specific complex, which is involved in the blood coagulation cascade. ANXA5 Protein, Human, Recombinant (His) is expressed in yeast with N-6xHis tag. The predicted molecular weight is 37.8 kDa and the accession number is P08758.
TMPH-03121	CXCL4 Protein, Pig, Recombinant (His & Myc) SCYB4,CXCL4,PF4,Platelet factor 4,PF-4,C-X-C motif chemokine...	Sus scrofa (Pig)	E. coli
	Released during platelet aggregation. Neutralizes the anticoagulant effect of heparin because it binds more strongly to heparin than to the chondroitin-4-sulfate chains of the carrier molecule. Chemotactic for neutrophils and monocytes. Inhibits endothelial cell proliferation. CXCL4 Protein, Pig, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 17.1 kDa and the accession number is P30034.
TMPY-00540	ANXA5 Protein annexin A5
	The placental anticoagulant protein Annexin A5 (ANXA5) is a multifunctional protein that is highly expressed on the apical surfaces of syncytiotrophoblasts, and plays an important role in haemostatic regulations, maintaining blood fluidity of the placenta. Annexin A5 (ANXA5) is a protein abundantly expressed in normal placenta where it contributes to the healthy outcome of a pregnancy. Lower ANXA5 levels have been observed in M2/ANXA5 haplotype carrying chorion. The association found between the...
TMPH-02832	Serpin A5 Protein, Mouse, Recombinant (His) Protein C inhibitor,Plasminogen activator inhibitor 3,Serpin...	Mouse	Baculovirus Insect Cells
	Heparin-dependent serine protease inhibitor acting in body fluids and secretions. Inactivates serine proteases by binding irreversibly to their serine activation site. Involved in the regulation of intravascular and extravascular proteolytic activities. Plays hemostatic roles in the blood plasma. Acts as a procoagulant and proinflammatory factor by inhibiting the anticoagulant activated protein C factor as well as the generation of activated protein C factor by the thrombin/thrombomodulin comple...
TMPJ-00490	Serpin A5 Protein, Human, Recombinant (His) Plasminogen Activator Inhibitor 3,Acrosomal Serine Protease ...	Human	HEK293 Cells
	Serpin A5 is a member of the human Serpin superfamily consists of at least 35 members. It is synthesized in the liver and has been detected in saliva, cerebral spinal fluid, amniotic fluid, tears and semen. As a potent inhibitor of the protein C anticoagulant pathway at the levels of both zymogen activation and enzyme inhibition, Serpin A5 additionally inhibits a variety of serine protease including thrombin, factor Xa, several kallekreins and acrosin. It plays a critical role in the processes o...
TMPY-00741	CXCL4 Protein, Human, Recombinant PF-4,platelet factor 4,SCYB4,CXCL4	Human	E. coli
	Platelet factor 4 (PF4), also known as chemokine (C-X-C motif) ligand 4 (CXCL4), is a small cytokine belonging to the CXC chemokine family. CXCL4/PF4 is released from the alpha-granules of activated platelets and binds with high affinity to heparin. Its major physiologic role appears to be neutralization of heparin-like molecules on the endothelial surface of blood vessels, thereby inhibiting local antithrombin III activity and promoting coagulation. As a strong chemoattractant for neutrophils a...

重组蛋白

TAP Protein, Ornithodoros moubata, Recombinant (His)

Cat.No: TMPH-03070

Species: Ornithodoros moubata

Expression System: P. pastoris (Yeast)

TAP Protein, Ornithodoros moubata, Recombinant (His & Myc & SUMO)

Cat.No: TMPH-03071

Species: Ornithodoros moubata

Expression System: E. coli

ANXA8 Protein, Human, Recombinant

Cat.No: TMPJ-00844

Species: Human

Expression System: E. coli

ANXA3 Protein, Human, Recombinant

Cat.No: TMPJ-00840

Species: Human

Expression System: E. coli

ANXA3 Protein, Human, Recombinant (His)

Cat.No: TMPH-00936

Species: Human

Expression System: E. coli

ANXA2 Protein, Human, Recombinant

Cat.No: TMPJ-00799

Species: Human

Expression System: E. coli

TPSAB1 Protein, Human, Recombinant (His)

Cat.No: TMPJ-01204

Species: Human

Expression System: HEK293 Cells

ANXA5 Protein, Human, Recombinant (His)

Cat.No: TMPH-00938

Species: Human

Expression System: P. pastoris (Yeast)

CXCL4 Protein, Pig, Recombinant (His & Myc)

Cat.No: TMPH-03121

Species: Sus scrofa (Pig)

Expression System: E. coli

Cat.No: TMPY-00540

Expression System:

Serpin A5 Protein, Mouse, Recombinant (His)

Cat.No: TMPH-02832

Species: Mouse

Expression System: Baculovirus Insect Cells

Serpin A5 Protein, Human, Recombinant (His)

Cat.No: TMPJ-00490

Species: Human

Expression System: HEK293 Cells

CXCL4 Protein, Human, Recombinant

Cat.No: TMPY-00741

Species: Human

Expression System: E. coli

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