131
23
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38
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Cat. No. | Product Name | ||
---|---|---|---|
L7110 | 抗高血压化合物库 | 678 compounds | |
678 种高血压相关的小分子,用于高通量和高内涵筛选; |
Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T1484 |
Perindoprilat
Perindoprilate,培哚普利 |
RAAS; MRP; AChR | Endocrinology/Hormones; Immunology/Inflammation; Neuroscience |
Perindoprilat (Perindoprilate) 是一种血管紧张素转换酶抑制剂。 | |||
T7510 |
Leucylarginylproline
|
RAAS | Endocrinology/Hormones |
Leucylarginylproline 是一种血管紧张素转换酶抑制剂,IC50=为0.27μM。 | |||
T1489 |
Fosinopril sodium
SQ28555,福辛普利钠 |
RAAS | Endocrinology/Hormones |
Fosinopril sodium 是一种血管紧张素转换酶(ACE)抑制剂的前药,能够作用于高血压和慢性心力衰竭。 | |||
T13865 |
Resorcinolnaphthalein
|
RAAS | Endocrinology/Hormones |
Resorcinolnaphthalein 是一种特异性的血管紧张素转换酶 2 激活剂,EC50=19.5 μM。Resorcinolnaphthalein 能够用于高血压和肾纤维化的研究 | |||
T7714 |
Temocapil
|
Tyrosinase | Proteases/Proteasome |
Temocapil 是一种酪氨酸激酶抑制剂。 | |||
T16116 |
MLN-4760
|
RAAS | Endocrinology/Hormones |
MLN-4760 是选择性的人ACE2抑制剂,IC50=0.44 nM,对人ACE2的选择性是其他相关蛋白的 5000 多倍,包括人睾丸 ACE (IC50,>100 μM) 和牛 carboxypeptidase A (IC50,27 μM)。 | |||
T1145 |
Diminazene Aceturate
DIZE |
Others; Serine Protease; Parasite | Microbiology/Virology; Others; Proteases/Proteasome |
Diminazene aceturate 是血管紧张素转化酶 2 的激活剂,具有强效抗炎特性。它还是一种抗锥虫药物,适用于牲畜。它主要生化机理是通过与富含腺嘌呤-胸腺嘧啶碱基对的位点发生特异性相互作用,以非插入方式与锥虫动子体 DNA 结合。 | |||
T7339 |
Angiotensin (1-7)
Ang-(1-7),Angiotensin 1-7,ASP-ARG-VAL-TYR-ILE-HIS-PRO |
RAAS; Endogenous Metabolite | Endocrinology/Hormones; Metabolism |
Angiotensin (1-7) (ASP-ARG-VAL-TYR-ILE-HIS-PRO) 是肾素-血管紧张素系统中的内源性七肽。Angiotensin 1-7在心肌细胞中具有抗炎和抗纤维化活性,因此具有心脏保护作用。它能抑制血管紧张素转换酶和释放一氧化氮,是激肽诱导的血管舒张的局部协同调节剂。它阻断 Ang II 诱导的平滑肌细胞增殖和肥大,并显示对内皮的抗血管生成和生长抑制作用。它显示出抗炎活性。 | |||
TP1828 |
N-Acetyl-Ser-Asp-Lys-Pro
|
RAAS | Endocrinology/Hormones |
N-Acetyl-Ser-Asp-Lys-Pro 通过酶促处理胸腺素 β4 在骨髓细胞中形成。 它抑制多能造血干细胞进入细胞周期的 S 期,并防止小鼠中的 Ara-C 致死性。 | |||
T7686 |
Ramiprilat
|
RAAS | Endocrinology/Hormones |
Ramiprilat 是 Ramipril 的活性代谢物,是一种口服有活力的血管紧张素转换酶 (ACE) 抑制剂,其 Ki=7 pM。它可用于研究心力衰竭以及高血压。 | |||
T6340 |
Enalaprilat Dihydrate
依那普利拉二水合物,MK-422,MK-422 Dihydrate |
RAAS; Autophagy | Autophagy; Endocrinology/Hormones |
Enalaprilat Dihydrate (MK-422 Dihydrate) 是一种有效的血管紧张素转化酶抑制剂,IC50为 1.94 nM。 | |||
T1605 |
Enalapril
MK-421,依那普利 |
RAAS; MRP | Endocrinology/Hormones; Immunology/Inflammation |
Enalapril 是一种血管紧张素转换酶(ACE)抑制剂。 | |||
T7808 |
Alacepril
Cetapril,阿拉普利,DU-1219 |
RAAS | Endocrinology/Hormones |
Alacepril (DU-1219) 是一种具有口服活性血管紧张素转换酶 (ACE) 抑制剂,具有长效抗高血压作用。 | |||
T6698 |
Temocapril hydrochloride
CS-622 HCl,Acecol,Temocapril HCl,CS-622,盐酸替莫普利 |
RAAS | Endocrinology/Hormones |
Temocapril hydrochloride (CS-622 HCl) 是血管紧张素转化酶 (ACE) 抑制剂。Temocapril HCl 能够用于充血性心力衰竭、急性心肌梗死、高血压、胰岛素抵抗和肾脏疾病的研究。 | |||
T1645 |
Ramipril
HOE-498,Tritace,雷米普利,Altace,Carasel |
Apoptosis; RAAS | Apoptosis; Endocrinology/Hormones |
Ramipril (Altace) 是一种ACE 抑制剂,IC50为5 nM。 | |||
T76169 |
Angiotensin-converting enzyme
|
||
Angiotensin-converting enzyme (ACE)血管紧张素转换酶是一种二羧基肽酶,它将非活性的血管紧张素 I (Ang I) 转化为活性的 Ang II,并降解活性的缓激肽 (BK)。Angiotensin-converting enzyme 是一种有效的血管收缩剂,常用于生化研究。 | |||
T5030 |
Zofenopril calcium
SQ26991,佐芬普利钙,Zofenopril (calcium) |
RAAS; Reactive Oxygen Species | Endocrinology/Hormones; Immunology/Inflammation; Metabolism; NF-κB |
Zofenopril calcium (SQ26991) 是一种抗氧化剂和血管紧张素转化酶 (ACE) 抑制剂。 | |||
T6542 |
Imidapril hydrochloride
Novaloc,Imidapril HCl,盐酸咪达普利,Tanapril,TA-6366 |
RAAS | Endocrinology/Hormones |
Imidapril hydrochloride (Tanapril) 是一种血管紧张素转换酶 (ACE) 抑制剂,具有抗高血压活性。 | |||
T0180 |
Benazepril hydrochloride
盐酸贝那普利,CGS 14824A HCl,Benazepril HCl,CGS14824A |
RAAS | Endocrinology/Hormones |
Benazepril hydrochloride (CGS 14824A HCl) 是一种血管紧张素转化酶(ACE)抑制剂,能够作用于高血压。 | |||
T2679 |
BMS-265246
BMS265246 |
CDK | Cell Cycle/Checkpoint |
BMS-265246 是一种有效的选择性 CDK1/2 抑制剂,对 CDK1/cyclin B 和 CDK2/cyclin E 的 IC50分别为6 nM 和9 nM。 | |||
T5329 |
Trandolapril
|
Angiotensin-converting Enzyme (ACE) | Metabolism |
Trandolapril 是 Trandolaprilat 的前体药物。Trandolapril 是一种口服血管紧张素转换酶抑制剂,在高血压和充血性心力衰竭及心肌梗死领域有研究价值。 | |||
T0706 |
Lisinopril dihydrate
Lisinopril,Renacor,赖诺普利二水合物,MK-521 (dihydrate) |
RAAS; MRP | Endocrinology/Hormones; Immunology/Inflammation |
Lisinopril dihydrate (MK-521) 是一种血管紧张素转化酶抑制剂。Lisinopri dihydrate 能够作用于高血压,充血性心力衰竭和心脏病等。 | |||
T3281 |
Delapril hydrochloride
indalapril,地拉普利盐酸盐,Alindapril Hydrochloride,Delapril Hydrochloride,盐酸地拉普利,CV 3317 |
RAAS | Endocrinology/Hormones |
Delapril hydrochloride (indalapril) 是一种血管紧张素转化酶抑制剂,能够用于心血管疾病的研究。 | |||
T0805 |
Quinapril hydrochloride
CI-906,PD-109452-2,盐酸喹那普利,Quinapril HCl |
RAAS | Endocrinology/Hormones |
Quinapril hydrochloride (PD-109452-2) 是一种血管紧张素转化酶(ACE) 抑制剂的原药。 | |||
T1484L |
Perindopril erbumine
培哚普利叔丁胺,培哚普利叔丁胺盐,S9490-3,Perindopril tert-butylamine salt |
Apoptosis; RAAS; MRP | Apoptosis; Endocrinology/Hormones; Immunology/Inflammation |
Perindopril erbumine (S9490-3) 是一种长效血管紧张素转换酶抑制剂。 | |||
T1462 |
Captopril
SQ 14225,甲巯丙脯酸,卡托普利,SQ-14534,SA333 |
RAAS | Endocrinology/Hormones |
Captopril (SA333) 是一种含巯基的,具有口服活性的血管紧张素转换酶(ACE)抑制剂 ,IC50=0.025 μM,广泛应用于高血压和充血性心力衰竭的研究。Captopril 也是NDM-1抑制剂,IC50=7.9 μM。 | |||
T6595 |
Moexipril hydrochloride
莫昔普利盐酸盐,Moexipril HCl,RS-10085,SPM 925,CI-925 |
Apoptosis; RAAS | Apoptosis; Endocrinology/Hormones |
Moexipril hydrochloride (Moexipril HCl) 是一种有口服活性的,不含巯基的血管紧张素转化酶抑制剂,可治疗高血压和充血性心力衰竭。 | |||
T6486 |
Enalapril Maleate
MK-421 Maleate,Renitec Maleate,Glioten Maleate,MK-421 (maleate),Vasotec Maleate,马来酸依那普利 |
RAAS | Endocrinology/Hormones |
Enalapril Maleate (MK-421 Maleate) 一种是血管紧张素转化酶(ACE)抑制剂。 | |||
T6444 |
Cilazapril Monohydrate
Ro 31-2848 monohydrate,Justor,西拉普利,西拉普利水合物 |
RAAS | Endocrinology/Hormones |
Cilazapril Monohydrate (Justor) 是一种血管紧张素转化酶抑制剂,能够作用于高血压和充血性心力衰竭的研究。 | |||
T25832 |
Moveltipril
Moveltipril calcium,MC-838,Altiopril calcium |
RAAS | Endocrinology/Hormones |
Moveltipril (Moveltipril calcium) 是一种强效血管紧张素转换酶(ACE)抑制剂。 | |||
T27827 |
Libenzapril
CGS 16617,Abutapril |
Angiotensin-converting Enzyme (ACE) | Metabolism |
Libenzapril (CGS 16617)是一种有效的血管紧张素转换酶抑制剂,可用于研究心肌损伤。 | |||
T24588 |
Palatrigine
BW-A 256C,BW A256C |
Adrenergic Receptor; Angiotensin-converting Enzyme (ACE) | GPCR/G Protein; Metabolism; Neuroscience |
Palatrigine (BW-A 256C) 是一种具有血管紧张素转换酶抑制和β肾上腺素受体阻断特性的化合物。 | |||
T68171L |
Zabicipril HCl
Zabicipril HCl(83059-56-7 Free base),S 9650,S 10211 |
Angiotensin-converting Enzyme (ACE) | Metabolism |
Zabicipril HCl(S 9650) 是一种有效的血管紧张素转换酶抑制剂。 | |||
T27357 |
FPL-62129
FPL 62129,FPL62129 |
RAAS; Calcium Channel | Endocrinology/Hormones; Membrane transporter/Ion channel; Metabolism |
FPL-62129 是一种钙通道拮抗剂,也是一种新型血管紧张素转换酶抑制剂,具有血管扩张活性,可用于研究心血管疾病。 | |||
T25226 |
Ceronapril
Ceronaprilum,SQ 29852,SQ-29852,SQ29852 |
RAAS | Endocrinology/Hormones |
Ceronapril (SQ 29852) 是一种具有口服活性和高效性的血管紧张素转换酶 (ACE) 抑制剂(IC50 : 36 nM),可用于研究痴呆和高血压。 | |||
T10671 |
Candoxatril
UK 79300 |
Neprilysin | Metabolism |
Candoxatril (UK 79300) 是具有口服活性的中性肽链内切酶 (NEP,EC 3.4.24.11) 抑制剂,可改善接受血管紧张素转换酶抑制的慢性心力衰竭患者的运动能力。 | |||
T20689 |
Temocaprilat
RNH-5139,RS-5139,RNH 5139,RNH5139,替莫普利,RS5139,RS 5139 |
Angiotensin-converting Enzyme (ACE) | Metabolism |
Temocaprilat (RS5139) 是一种血管紧张素转换酶 (ACE) 抑制剂。 Temocaprilat 通过缺乏 EHBR 的 cMOAT 有效地从胆汁中排泄,而许多其他 ACE 抑制剂对 cMOAT 的亲和力较低。 | |||
T68171 |
Zabicipril
|
RAAS | Endocrinology/Hormones |
Zabicipril 是一种新型可口服的血管紧张转换酶抑制剂,是一种前药,在体内脱酯后具有抗高血压活性。 | |||
T24906L |
Tuna AI acetate
|
Angiotensin-converting Enzyme (ACE) | Metabolism |
Tuna AI acetate 是一种源自金枪鱼肌肉的非竞争性血管紧张素转换酶 (ACE) 抑制剂。 | |||
TP1750L |
H-Ile-Pro-Pro-OH acetate
H-Ile-Pro-Pro-OH acetate(26001-32-1 free base) |
Angiotensin-converting Enzyme (ACE) | Metabolism |
H-Ile-Pro-Pro-OH acetate 是一种血管紧张素转换酶抑制剂,为乳源三肽。 | |||
T9109 |
SSAA09E2
|
RAAS; SARS-CoV | Endocrinology/Hormones; Microbiology/Virology |
SSAA09E2 是一种新型的SARS-CoV 复制抑制剂,通过阻断SARS-S 与SARS-CoV 受体血管紧张素转换酶-2 的早期相互作用发挥作用。 | |||
TP1295 |
Angiotensin I (human, mouse, rat)
Angiotensin 1 Human,血管紧张素 1 (人) |
Others | Others |
Angiotensin I (human, mouse, rat) 是血管紧张素Ⅱ的前体物质,在血管紧张素转化酶 (ACE) 的参与下裂解成血管紧张素Ⅱ。 | |||
TP1682L |
Abz-FR-K(Dnp)-P-OH acetate
Abz-FR-K(Dnp)-P-OH acetate (500799-61-1 free base) |
Others | Others |
Abz-FR-K(Dnp)-P-OH acetate(500799-61-1 free base) 是一种出色的血管紧张素 I 转换酶 (ACE) 底物,Km 值为 4.0 μM,kcat 值为 210s-1。 | |||
T7354 |
H-Val-Pro-Pro-OH
|
RAAS | Endocrinology/Hormones |
H-Val-Pro-Pro-OH 是一种血管紧张素 I 转化酶(ACE)的抑制剂(IC50:9 μM)。他是一种来源于牛奶的脯氨酸肽衍生物。 | |||
TP1920L1 |
Acein acetate
|
RAAS | Endocrinology/Hormones |
Acein acetate 是高亲和力血管紧张素转换酶 (ACE) 配体 (Kd = 2.79 nM)。浓度高达 500 nM 时对 ACE 酶活性没有显着影响。增强 NMDA + D-丝氨酸诱导的多巴胺从体外纹状体切片和体内纹状体的释放。 | |||
TP1404L |
Hemorphin-7 acetate(152685-85-3 free base)
|
Opioid Receptor | Endocrinology/Hormones; GPCR/G Protein; Neuroscience |
Hemorphin-7 acetate(152685-85-3 free base) 是一种 hemorphin 肽,一种源自血红蛋白 β 链的内源性阿片肽。 Hemorphin 肽具有镇痛和抗高血压活性,可激活阿片受体并抑制血管紧张素转换酶 (ACE)。 | |||
T25515 |
I5B2
I5 B2,I5-B2 |
Others | Others |
I5B2 is a novel phosphorus-containing angiotensin I converting enzyme inhibitor. Angiotensin I converting enzyme is produced by Actinomadura sp. | |||
T21049 |
Quinaprilat
CI-928,CI928,CI 928 |
Others | Others |
Quinaprilat inhibits angiotensin converting enzyme. | |||
T28581 |
Ro 31-2201
Ro 312201,Ro-31-2201 |
Others | Others |
Ro 31-2201 is a potent inhibitor of angiotensin converting enzyme. | |||
T27608 |
Indolapril hydrochloride
REV 6000A(SS),CI-907,CI 907,CI907,Indolapril HCl |
Others | Others |
Indolapril hydrochloride is a nonsulfhydryl angiotensin converting enzyme (ACE) inhibitor with antihypertensive activity. |
Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T5S0106 |
Peimisine
贝母辛,Ebeiensine |
RAAS; AChR | Endocrinology/Hormones; Neuroscience |
Peimisine (Ebeiensine) 非竞争性拮抗气管平滑肌 M 受体,抑制 Ach 引起的平滑肌收缩。它兴奋 β 受体和拮抗内钙释放,促进一氧化氮释放,可舒张气管平滑肌,有平喘作用。 | |||
T8270 |
Deserpidine
地舍平,Harmonyl |
RAAS | Endocrinology/Hormones |
Deserpidine (Harmonyl) 是从 Rauwolfia canescens 的根中分离的生物碱。Deserpidine 与 Reserpine 相关。Deserpidine 是竞争性血管紧张素转化酶抑制剂,可以被用作抗高血压药以及镇定剂。Deserpidine 还减少了肾上腺皮质血管紧张素 II 诱导的醛固酮分泌。 | |||
T13299 |
Vicenin 3
维采宁-3,维采宁 3 |
RAAS | Endocrinology/Hormones |
Vicenin 3来源于广金钱草的地上部分。Vicenin 3是血管紧张素转换酶抑制剂,IC50=46.91 μM。 | |||
T5796 |
Plantainoside D
Isoplantamajoside,车前草苷D |
RAAS; PKC | Chromatin/Epigenetic; Cytoskeletal Signaling; Endocrinology/Hormones |
Plantainoside D (Isoplantamajoside) 可以抑制 ACE ,IC50=2.17 mM。Plantainoside D 也是IKK-β抑制剂。 | |||
T21418 |
Lisinopril
Linopril,赖诺普利,Zestril,Prinivil,Lisipril |
RAAS | Endocrinology/Hormones |
Lisinopril (Prinivil) 是一种血管紧张素转化酶抑制剂,能够作用于高血压,充血性心力衰竭和心脏病等。 | |||
T3851 |
Vicenin 2
Vicenin -2,维采宁 2,新西兰牡荆苷 |
RAAS | Endocrinology/Hormones |
Vicenin 2 来源于广金钱草 (Desmodium styracifolium) 的地上部分。Vicenin 2 是一种血管紧张素转换酶 (ACE) 抑制剂,IC50=43.83 μM。 | |||
T3753 |
Sinapinic Acid
Sinapic acid,芥子酸,Synapoic acid |
Apoptosis; RAAS; Reactive Oxygen Species; HDAC | Apoptosis; Chromatin/Epigenetic; DNA Damage/DNA Repair; Endocrinology/Hormones; Immunology/Inflammation; Metabolism; NF-κB |
Sinapinic Acid (Synapoic acid) 是从 Hydnophytum formicarumJack. 根中分离到的酚类,是HDAC 抑制剂,对ACE-I 的活性也有抑制作用。它有抗肿瘤活性,诱导肿瘤细胞凋亡,具有抗氧化、抗糖尿病的作用。 | |||
T6627 |
Phosphoramidon Disodium
Phosphoramidon Disodium Salt,磷酰胺二钠 |
RAAS; Neprilysin; Others | Endocrinology/Hormones; Metabolism; Others |
Phosphoramidon Disodium (Phosphoramidon Disodium Salt) Salt 是一种金属蛋白酶 (metalloprotease) 抑制剂 。Phosphoramidon Disodium Salt 抑制内皮素转化酶 (ECE) ,中性肽内切酶 (NEP) 和血管紧张素转换酶 (ACE) 的IC50分别为 3.5 ,0.034 和 78 μM。 | |||
TN2295 |
Vicenin-1
Vicenin -1 |
Antioxidant; Angiotensin-converting Enzyme (ACE) | Metabolism; oxidation-reduction |
Vicenin-1 (Vicenin -1) 是一种来自豆科植物胡卢巴种子中分离出来的类黄酮糖苷,具有强大的抗炎和抗氧化活性,抑制血管紧张素转换酶 (ACE) 。 | |||
TN1464 |
Camellianin A
|
Apoptosis; RAAS | Apoptosis; Endocrinology/Hormones |
Camellianin A 是从 A. nitida 和 茶叶中提取得到的类黄酮列化合物,具有抗癌活性,抑制血管紧张素转换酶 (ACE) 活性,促进 Hep G2 和 MCF-7 细胞凋亡。Camellianin A 可预防CCl4-通过施加抗氧化应激、抗炎和抗细胞凋亡诱导肝损伤。 | |||
T38649 |
Lyciumin A
|
Others | Others |
Lyciumin A, a cyclic octapeptide, possesses inhibitory properties against proteases, renin, and angiotensin-converting enzyme. It holds potential for hypertension research. | |||
TN4103 |
Ganoderic acid K
|
||
Ganoderic acid K is an angiotensin-converting enzyme inhibitor. It has anti-tumor, and anti-inflammatory activities. | |||
T38481 |
Camellianin B
|
Others | Others |
Camellianin B, a flavonoid compound and metabolite of Camellianin A, exhibits antioxidant properties and acts as an angiotensin converting enzyme (ACE) inhibitor. | |||
TN2045 |
Pelargonidin-3-O-glucoside chloride
|
Others; Estrogen/progestogen Receptor | Endocrinology/Hormones; Others |
Pelargonidin-3-O-glucopyranoside is the glucoside of Pelargonidin, an potential antidiabetic agent. Pelargonidin-3-O-glucopyranoside has antioxidant, anti-inflammatory, anti-estrogenic, and angiotensin-converting enzyme inhibitory activities. | |||
T19911 |
Rescinnamine
Anaprel,Apoterin S,Apoterin |
Others | Others |
Rescinnamine is an inhibitor of angiotensin-converting enzyme. It also is a vinca alkaloid obtained from Rauwolfia serpentina and other species of Rauwolfia. It used as an antihypertensive drug. | |||
TN1060 |
Ganoderol A
灵芝醇 A,灵芝醇A |
Others | Others |
Ganoderol A has significant anti-inflammatory activity and protection against UVA damage. it has an inhibitory effect on angiotensin converting enzyme activity and cholesterol biosynthesis. | |||
TN5645 |
Isomartynoside
|
||
Isomartynoside has inhibition against the angiotensin converting enzyme (ACE) activities, the IC 50 value is 505±26.7μg/ml, it may have antihypertensive effect. Isomartynoside also shows obvious anti-fatigue activity. | |||
TN2487 |
1,3,5,6-Tetrahydroxyxanthone
|
Others | Others |
1,3,5,6-Tetrahydroxyxanthone shows moderate hepatoprotective activity with EC(50) values of 160.2 +/- 0.6 microM against tacrine-induced cytotoxicity in HepG2 cells. It can inhibit angiotensin-I-converting-enzyme activity in a dose-dependent manner. | |||
TN4860 |
Pueroside B
|
COX; PPAR | DNA Damage/DNA Repair; Immunology/Inflammation; Metabolism; Neuroscience |
Pueroside B may can treat coronary heart disease, it can interact with two or more targets[peroxisome proliferator activated receptor γ (PPAR-γ), angiotensin-converting enzyme (ACE), hydroxymethylglutaryl coenzyme A receptor (HMGR), cyclooxygenase-2 (COX2 | |||
TN4431 |
Leucosceptoside A
|
RAAS; PKC | Chromatin/Epigenetic; Cytoskeletal Signaling; Endocrinology/Hormones |
Leucosceptoside A shows inhibitory activity against PKCalpha with the IC50 value of 19.0 microM; it also exhibits strong inhibitory capacity against α-glucosidase. Leucosceptoside A has antihypertensive effect, it shows angiotensin converting enzyme (ACE) | |||
TN1061 |
Ganoderol B
|
Androgen Receptor | Endocrinology/Hormones |
Ganoderol B is a potent β ±-glucosidase and angiotensin-converting enzyme inhibitor, with an IC(50) of β ±-glucosidase is 119.8 uM. It may be useful in prostate cancer and benign prostatic hyperplasia (BPH) therapy through suppressing the function of andr | |||
T79958 |
Isocrenatoside
|
Angiotensin-converting Enzyme (ACE) | Metabolism |
Isocrenatoside (compound 6)为环状八肽,具有ACE抑制活性。该化合物可通过乙醇提取Microtoena prainiana茎部分离纯化。研究显示,1 mg/mL浓度下,Isocrenatoside的ACE抑制效率高达99.3%。 | |||
TN1104 |
Cyanidin 3-sambubioside chloride
Cyanidin-3-O-sambubioside chloride |
RAAS; Antioxidant; NO Synthase | Endocrinology/Hormones; Immunology/Inflammation; oxidation-reduction |
Cyanidin 3-sambubioside chloride (Cyanidin-3-O-sambubioside chloride) 是一种从植物中提取的花青素,是一种 NO和 H274Y 突变的抑制剂,对流感神经氨酸酶具有抑制作用。Cyanidin 3-sambubioside chloride 具有抗氧化,抗血管生成和抗病毒活性,抑制血管紧张素转换酶 (ACE) 的活性,可用于研究病毒感染和心血管疾病。 |
Cat. No. | Product Name | Species | Expression System |
---|---|---|---|
TMPY-02207 |
ACE2/ACEH Protein, Rat, Recombinant (His)
angiotensin I converting enzyme 2 |
Rat | HEK293 Cells |
ACE2/ACEH Protein, Rat, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 85 kDa and the accession number is Q5EGZ1. | |||
TMPY-01838 |
ACE2/ACEH Protein, Mouse, Recombinant (His)
angiotensin I converting enzyme 2,2010305L... |
Mouse | HEK293 Cells |
ACE2/ACEH Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 85 kDa and the accession number is Q8R0I0-1. | |||
TMPY-01839 |
ACE2/ACEH Protein, Mouse, Recombinant (His & hFc)
2010305L05Rik,angiotensin I converting enz... |
Mouse | HEK293 Cells |
ACE2/ACEH Protein, Mouse, Recombinant (His & hFc) is expressed in HEK293 mammalian cells with His and hFc tag. The predicted molecular weight is 112 kDa and the accession number is Q8R0I0-1. | |||
TMPY-03830 |
ACE2/ACEH Protein, Rhesus, Recombinant (His)
angiotensin I converting enzyme 2 |
Rhesus | HEK293 Cells |
ACE2/ACEH Protein, Rhesus, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 85.1 kDa and the accession number is B6DUF3. | |||
TMPY-03561 |
ACE2/ACEH Protein, Rhesus, Recombinant (hFc)
angiotensin I converting enzyme 2 |
Rhesus | HEK293 Cells |
ACE2/ACEH Protein, Rhesus, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 110.7kDa and the accession number is B6DUF3. | |||
TMPY-04312 |
ACE2/ACEH Protein, Human, Recombinant (mFc)
angiotensin I converting enzyme 2,ACEH |
Human | HEK293 Cells |
ACE2/ACEH Protein, Human, Recombinant (mFc) is expressed in HEK293 mammalian cells with mFc tag. The predicted molecular weight is 110 kDa and the accession number is Q9BYF1-1. | |||
TMPY-05266 |
ACE2/ACEH Protein, Human, Recombinant (His)
ACEH,angiotensin I converting enzyme 2 |
Human | HEK293 Cells |
ACE2/ACEH Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 85.1 kDa and the accession number is Q9BYF1-1. | |||
TMPY-05725 |
ACE2/ACEH Protein, Human, Recombinant (His & Avi), Biotinylated
angiotensin I converting enzyme 2,ACEH |
Human | Baculovirus Insect Cells |
ACE2/ACEH Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in Baculovirus insect cells with His and Avi tag. The predicted molecular weight is 86.86 kDa and the accession number is Q9BYF1-1. | |||
TMPY-06334 |
ACE2/ACEH Protein, Human, Recombinant (hFc), Biotinylated
ACEH,angiotensin I converting enzyme 2 |
Human | HEK293 Cells |
ACE2/ACEH Protein, Human, Recombinant (hFc), Biotinylated is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 110.3 kDa and the accession number is NP_068576.1. | |||
TMPJ-00386 |
ACE2/ACEH Protein, Human, Recombinant (HEK293, His & Avi), Biotinylated
Metalloprotease MPROT15,ACEH,Angiotensin-Conver... |
Human | HEK293 Cells |
Angiotensin-Converting Enzyme 2 (ACE-2) is an integral membrane protein and a zinc metalloprotease of the ACE family, the ACE family includes somatic and germinal ACE. ACE-2 cleaves angiotensins I and II as a carboxypeptidase, ACE-2 converts angiotensin I to angiotensin 1-9, and angiotensin II to angiotensin 1-7. ACE-2 is also able to hydrolyze apelin-13 and dynorphin-13 with high efficiency. ACE-2 can be high expressed in testis, kidney and heart, in colon, small intestine and ovary at moderate... | |||
TMPY-05696 |
ACE2/ACEH Protein, Human, Recombinant (His), Biotinylated
ACEH,angiotensin I converting enzyme 2 |
Human | HEK293 Cells |
ACE2/ACEH Protein, Human, Recombinant (His), Biotinylated is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 85.1 kDa and the accession number is Q9BYF1-1. | |||
TMPY-00655 |
ACE2/ACEH Protein, Human, Recombinant (hFc)
angiotensin I converting enzyme 2,ACEH |
Human | HEK293 Cells |
ACE2/ACEH Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 110.3 kDa and the accession number is Q9BYF1-1. | |||
TMPH-03081 |
ACE2 Protein, Paguma larvata, Recombinant (hFc)
EC:3.4.17.23,Angiotensin-converting enzyme... |
Paguma larvata | HEK293 Cells |
ACE2 Protein, Paguma larvata, Recombinant (hFc) is expressed in HEK293 mammalian cells with C-hFc tag. The predicted molecular weight is 112.7 kDa and the accession number is Q56NL1. | |||
TMPK-00383 |
ACE2/ACEH Protein, Human, Recombinant (His & Avi)
ACE2,ACE-2,ACEH |
Human | HEK293 Cells |
ACE2 (Angiotensin I Converting Enzyme 2) is a Protein Coding gene. Diseases associated with ACE2 include Severe Acute Respiratory Syndrome and Neurogenic Hypertension.The protein encoded by this gene belongs to the angiotensin-converting enzyme family of dipeptidyl carboxydipeptidases and has considerable homology to human angiotensin 1 converting enzyme. This secreted protein catalyzes the cleavage of angiotensin I into angiotensin 1-9, and angiotensin II into the vasodilator angiotensin 1-7. A... | |||
TMPK-00552 |
ACE2/ACEH Protein, Cynomolgus, Recombinant (His & Avi), Biotinylated
ACEH,ACE-2,ACE2 |
Cynomolgus | HEK293 Cells |
ACE2 (Angiotensin I Converting Enzyme 2) is a Protein Coding gene. Diseases associated with ACE2 include Severe Acute Respiratory Syndrome and Neurogenic Hypertension.The protein encoded by this gene belongs to the angiotensin-converting enzyme family of dipeptidyl carboxydipeptidases and has considerable homology to human angiotensin 1 converting enzyme. This secreted protein catalyzes the cleavage of angiotensin I into angiotensin 1-9, and angiotensin II into the vasodilator angiotensin 1-7. A... | |||
TMPK-00551 |
ACE2/ACEH Protein, Cynomolgus, Recombinant (His & Avi)
ACE-2,ACEH,ACE2 |
Cynomolgus | HEK293 Cells |
ACE2 (Angiotensin I Converting Enzyme 2) is a Protein Coding gene. Diseases associated with ACE2 include Severe Acute Respiratory Syndrome and Neurogenic Hypertension.The protein encoded by this gene belongs to the angiotensin-converting enzyme family of dipeptidyl carboxydipeptidases and has considerable homology to human angiotensin 1 converting enzyme. This secreted protein catalyzes the cleavage of angiotensin I into angiotensin 1-9, and angiotensin II into the vasodilator angiotensin 1-7. A... | |||
TMPK-00382 |
ACE2/ACEH Protein, Human, Recombinant (hFc & Avi), Biotinylated
ACE-2,ACE2,ACEH |
Human | HEK293 Cells |
ACE2 (Angiotensin I Converting Enzyme 2) is a Protein Coding gene. Diseases associated with ACE2 include Severe Acute Respiratory Syndrome and Neurogenic Hypertension.The protein encoded by this gene belongs to the angiotensin-converting enzyme family of dipeptidyl carboxydipeptidases and has considerable homology to human angiotensin 1 converting enzyme. This secreted protein catalyzes the cleavage of angiotensin I into angiotensin 1-9, and angiotensin II into the vasodilator angiotensin 1-7. A... | |||
TMPH-03352 |
KLKB1 Protein, Rat, Recombinant (His)
Fletcher factor,Klkb1,Plasma prekallikrein,Kininogenin,Plasm... |
Rat | P. pastoris (Yeast) |
The enzyme cleaves Lys-Arg and Arg-Ser bonds. It activates, in a reciprocal reaction, factor XII after its binding to a negatively charged surface. It also releases bradykinin from HMW kininogen and may also play a role in the renin-angiotensin system by converting prorenin into renin. KLKB1 Protein, Rat, Recombinant (His) is expressed in yeast with N-6xHis tag. The predicted molecular weight is 29.8 kDa and the accession number is P14272. | |||
TMPK-00432 |
SARS-COV-2 Spike S1 Protein (hFc & Avi)
Spike protein S1,S glycoprotein Subunit1,S1 protein,Spike,S1... |
SARS-CoV-2 | HEK293 Cells |
The spike protein (S) of coronavirus (CoV) attaches the virus to its cellular receptor, angiotensin-converting enzyme 2 (ACE2). A defined receptor-binding domain (RBD) on S mediates this interaction.The S protein plays key parts in the induction of neutralizing-antibody and T-cell responses, as well as protective immunity. SARS-COV-2 Spike S1 Protein (hFc & Avi) is expressed in HEK293 mammalian cells with C-hFc-Avi tag. The predicted molecular weight is 102.6 kDa and the accession number is A0A6... | |||
TMPK-00434 |
SARS-COV-2 Spike RBD Protein (hFc & Avi), Biotinylated
S protein RBD,S glycoprotein RBD,Spike protein RBD |
SARS-CoV-2 | HEK293 Cells |
The spike protein (S) of coronavirus (CoV) attaches the virus to its cellular receptor, angiotensin-converting enzyme 2 (ACE2). A defined receptor-binding domain (RBD) on S mediates this interaction.The S protein plays key parts in the induction of neutralizing-antibody and T-cell responses, as well as protective immunity. SARS-COV-2 Spike RBD Protein (hFc & Avi), Biotinylated is expressed in HEK293 mammalian cells with C-hFc-Avi tag. The predicted molecular weight is 51.7 kDa and the accession ... | |||
TMPK-00911 |
SARS Spike RBD Protein (His & Avi)
S protein RBD,Spike protein RBD,S glycoprotein RBD |
SARS | HEK293 Cells |
The spike protein (S) of coronavirus (CoV) attaches the virus to its cellular receptor, angiotensin-converting enzyme 2 (ACE2). A defined receptor-binding domain (RBD) on S mediates this interaction.The S protein plays key parts in the induction of neutralizing-antibody and T-cell responses, as well as protective immunity. SARS Spike RBD Protein (His & Avi) is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 27.9 kDa and the accession number is P59594. | |||
TMPK-00438 |
SARS-COV-2 Spike S Trimer Protein (His & Avi)
COVID-19,S protein,S glycoprotein,Spike glycoprotein |
SARS-CoV-2 | HEK293 Cells |
The spike protein (S) of coronavirus (CoV) attaches the virus to its cellular receptor, angiotensin-converting enzyme 2 (ACE2). A defined receptor-binding domain (RBD) on S mediates this interaction.The S protein plays key parts in the induction of neutralizing-antibody and T-cell responses, as well as protective immunity. SARS-COV-2 Spike S Trimer Protein (His & Avi) is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 136.6 kDa and the accession number i... | |||
TMPK-00908 |
SARS Spike S1 Protein (hFc & Avi)
Spike protein S1,S1 protein,Spike,S1 protein,S glycoprotein ... |
SARS | HEK293 Cells |
The spike protein (S) of coronavirus (CoV) attaches the virus to its cellular receptor, angiotensin-converting enzyme 2 (ACE2). A defined receptor-binding domain (RBD) on S mediates this interaction.The S protein plays key parts in the induction of neutralizing-antibody and T-cell responses, as well as protective immunity. SARS Spike S1 Protein (hFc & Avi) is expressed in HEK293 mammalian cells with C-hFc-Avi tag. The predicted molecular weight is 100.6 kDa and the accession number is P59594. | |||
TMPK-00913 |
SARS Spike S1 Protein (His & Avi), Biotinylated
Spike protein S1,S glycoprotein Subunit1,S1 protein,Spike,S1... |
SARS | HEK293 Cells |
The spike protein (S) of coronavirus (CoV) attaches the virus to its cellular receptor, angiotensin-converting enzyme 2 (ACE2). A defined receptor-binding domain (RBD) on S mediates this interaction.The S protein plays key parts in the induction of neutralizing-antibody and T-cell responses, as well as protective immunity. SARS Spike S1 Protein (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 75.9 kDa and the accession number ... | |||
TMPK-00440 |
SARS-COV-2 Spike S1 Protein (His & Avi), Biotinylated
S1 protein,S glycoprotein Subunit1,Spike,S1 protein,Spike pr... |
SARS-CoV-2 | HEK293 Cells |
The spike protein (S) of coronavirus (CoV) attaches the virus to its cellular receptor, angiotensin-converting enzyme 2 (ACE2). A defined receptor-binding domain (RBD) on S mediates this interaction.The S protein plays key parts in the induction of neutralizing-antibody and T-cell responses, as well as protective immunity. SARS-COV-2 Spike S1 Protein (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 77.9 kDa and the accession n... | |||
TMPK-00909 |
SARS Spike S1 Protein (hFc & Avi), Biotinylated
Spike protein S1,S glycoprotein Subunit1,Spike,S1 protein,S1... |
SARS | HEK293 Cells |
The spike protein (S) of coronavirus (CoV) attaches the virus to its cellular receptor, angiotensin-converting enzyme 2 (ACE2). A defined receptor-binding domain (RBD) on S mediates this interaction.The S protein plays key parts in the induction of neutralizing-antibody and T-cell responses, as well as protective immunity. SARS Spike S1 Protein (hFc & Avi), Biotinylated is expressed in HEK293 mammalian cells with C-hFc-Avi tag. The predicted molecular weight is 100.6 kDa and the accession number... | |||
TMPK-00442 |
SARS-COV-2 (Omicron B.1.1.529) Spike S Trimer Protein (His & Avi), Biotinylated
S glycoprotein,COVID-19,S protein,Spike glycoprotein |
SARS-CoV-2 | HEK293 Cells |
The spike protein (S) of coronavirus (CoV) attaches the virus to its cellular receptor, angiotensin-converting enzyme 2 (ACE2). A defined receptor-binding domain (RBD) on S mediates this interaction.The S protein plays key parts in the induction of neutralizing-antibody and T-cell responses, as well as protective immunity. SARS-COV-2 (Omicron B.1.1.529) Spike S Trimer Protein (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 13... | |||
TMPK-00439 |
SARS-COV-2 Spike RBD Protein (His & Avi), Biotinylated
S protein RBD,S glycoprotein RBD,Spike protein RBD |
SARS-CoV-2 | HEK293 Cells |
The spike protein (S) of coronavirus (CoV) attaches the virus to its cellular receptor, angiotensin-converting enzyme 2 (ACE2). A defined receptor-binding domain (RBD) on S mediates this interaction.The S protein plays key parts in the induction of neutralizing-antibody and T-cell responses, as well as protective immunity. SARS-COV-2 Spike RBD Protein (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 27 kDa and the accession nu... | |||
TMPK-00912 |
SARS Spike RBD Protein (His & Avi), Biotinylated
S glycoprotein RBD,S protein RBD,Spike protein RBD |
SARS | HEK293 Cells |
The spike protein (S) of coronavirus (CoV) attaches the virus to its cellular receptor, angiotensin-converting enzyme 2 (ACE2). A defined receptor-binding domain (RBD) on S mediates this interaction.The S protein plays key parts in the induction of neutralizing-antibody and T-cell responses, as well as protective immunity. SARS Spike RBD Protein (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 27.9 kDa and the accession number... | |||
TMPK-00441 |
SARS-COV-2 Spike S Trimer Protein (His & Avi), Biotinylated
Spike glycoprotein,S glycoprotein,S protein,COVID-19 |
SARS-CoV-2 | HEK293 Cells |
The spike protein (S) of coronavirus (CoV) attaches the virus to its cellular receptor, angiotensin-converting enzyme 2 (ACE2). A defined receptor-binding domain (RBD) on S mediates this interaction.The S protein plays key parts in the induction of neutralizing-antibody and T-cell responses, as well as protective immunity. SARS-COV-2 Spike S Trimer Protein (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 136.6 kDa and the acce... | |||
TMPK-00443 |
SARS-COV-2 (Omicron B.1.1.529) Spike S1 Protein (His & Avi), Biotinylated
Spike,S1 protein,S glycoprotein Subunit1,S1 protein,Spike pr... |
SARS-CoV-2 | HEK293 Cells |
The spike protein (S) of coronavirus (CoV) attaches the virus to its cellular receptor, angiotensin-converting enzyme 2 (ACE2). A defined receptor-binding domain (RBD) on S mediates this interaction.The S protein plays key parts in the induction of neutralizing-antibody and T-cell responses, as well as protective immunity. SARS-COV-2 (Omicron B.1.1.529) Spike S1 Protein (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 77.94 kD... | |||
TMPK-00444 |
SARS-COV-2 Spike S1 NTD Protein (His & Flag)
S1 protein NTD,Spike glycoprotein Subunit1 NTD,S glycoprotei... |
SARS-CoV-2 | HEK293 Cells |
The spike protein (S) of coronavirus (CoV) attaches the virus to its cellular receptor, angiotensin-converting enzyme 2 (ACE2). A defined receptor-binding domain (RBD) on S mediates this interaction.The S protein plays key parts in the induction of neutralizing-antibody and T-cell responses, as well as protective immunity. SARS-COV-2 Spike S1 NTD Protein (His & Flag) is expressed in HEK293 mammalian cells with C-His-Flag tag. The predicted molecular weight is 35 kDa and the accession number is A... | |||
TMPK-00910 |
SARS Spike S1 Protein (His & Avi)
S1 protein,S glycoprotein Subunit1,Spike protein S1,Spike,S1... |
SARS | HEK293 Cells |
The spike protein (S) of coronavirus (CoV) attaches the virus to its cellular receptor, angiotensin-converting enzyme 2 (ACE2). A defined receptor-binding domain (RBD) on S mediates this interaction.The S protein plays key parts in the induction of neutralizing-antibody and T-cell responses, as well as protective immunity. SARS Spike S1 Protein (His & Avi) is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 75.9 kDa and the accession number is P59594. | |||
TMPK-00437 |
SARS-COV-2 Spike RBD Protein (His & Avi)
S glycoprotein RBD,Spike protein RBD,S protein RBD |
SARS-CoV-2 | HEK293 Cells |
The spike protein (S) of coronavirus (CoV) attaches the virus to its cellular receptor, angiotensin-converting enzyme 2 (ACE2). A defined receptor-binding domain (RBD) on S mediates this interaction.The S protein plays key parts in the induction of neutralizing-antibody and T-cell responses, as well as protective immunity. SARS-COV-2 Spike RBD Protein (His & Avi) is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 27 kDa and the accession number is A0A6G7... | |||
TMPK-00433 |
SARS-COV-2 Spike S1 Protein (hFc & Avi), Biotinylated
S1 protein,Spike,S1 protein,Spike protein S1,S glycoprotein ... |
SARS-CoV-2 | HEK293 Cells |
The spike protein (S) of coronavirus (CoV) attaches the virus to its cellular receptor, angiotensin-converting enzyme 2 (ACE2). A defined receptor-binding domain (RBD) on S mediates this interaction.The S protein plays key parts in the induction of neutralizing-antibody and T-cell responses, as well as protective immunity. SARS-COV-2 Spike S1 Protein (hFc & Avi), Biotinylated is expressed in HEK293 mammalian cells with C-hFc-Avi tag. The predicted molecular weight is 102.6 kDa and the accession ... | |||
TMPH-03351 |
KLKB1 Protein, Rat, Recombinant (E. coli, His)
Plasma prekallikrein,Klkb1,Kininogenin,Plasma kallikrein,Fle... |
Rat | E. coli |
The enzyme cleaves Lys-Arg and Arg-Ser bonds. It activates, in a reciprocal reaction, factor XII after its binding to a negatively charged surface. It also releases bradykinin from HMW kininogen and may also play a role in the renin-angiotensin system by converting prorenin into renin. KLKB1 Protein, Rat, Recombinant (E. coli, His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 31.8 kDa and the accession number is P14272. | |||
TMPY-02574 |
Chymase 1 Protein, Human, Recombinant (His)
MCT1,chymase 1, mast cell,chymase,CYH |
Human | Baculovirus Insect Cells |
The STR polymorphism in the CMA1 gene is associated with asthma and that this association is even stronger with atopic asthma. CMA1 and IL-4 in atopic asthma and for IL-4 in atopy in general. The local angiotensin II system (LAS) has numerous functions, including the regulation of growth and differentiation in the gastrointestinal tract. Angiotensin II (AngII) may be generated by angiotensin-I-converting enzyme (ACE) or mast cell chymase (CMA1) and plays an important role in inflammatory process... | |||
TMPY-06885 |
SARS-CoV-2 XBB.1.16 (Omicron) Spike S1+S2 trimer Protein (ECD, His)
|
||
The spike (S) glycoprotein of coronaviruses contains protrusions that will only bind to certain receptors on the host cell. Known receptors bind S1 are ACE2, angiotensin-converting enzyme 2; DPP4, dipeptidyl peptidase-4; APN, aminopeptidase N; CEACAM, carcinoembryonic antigen-related cell adhesion molecule 1; Sia, sialic acid; O-ac Sia, O-acetylated sialic acid. The spike is essential for both host specificity and viral infectivity. The term 'peplomer' is typically used to refer to a grouping of... |
Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T11193 |
Enalaprilat-d5 sodium
MK-422 D5 Sodium Salt,依那普利拉钠 D5,Enalaprilat D5 Sodium Salt |
Others | Others |
Enalaprilat D5 Sodium Salt is the deuterium labeled Enalaprilat, which is an angiotensin-converting enzyme (ACE) inhibitor. | |||
T11192 |
Enalapril D5 maleate
MK-421 D5 maleate,马来酸依那普利D5 |
Others | Others |
Enalapril D5 maleate is deuterium labeled Enalapril, which is an angiotensin converting enzyme (ACE) inhibitor. | |||
T11194 |
Enalaprilat D5
MK-422 D5,依那普利拉 D5 |
Others | Others |
Enalaprilat D5 is the deuterium labeled Enalaprilat, which is an angiotensin-converting enzyme (ACE) inhibitor. | |||
T13196 |
Trandolaprilate D5
Trandolaprilat D5,RU 44403 D5 |
Others | Others |
Trandolaprilate D5 is a deuterium-labeled Trandolaprilate. Trandolaprilate is an inhibitor of angiotensin-converting enzyme (ACE). | |||
T13195 |
Trandolapril D5
RU44570 D5 |
Others | Others |
Trandolapril D5 is a deuterium labeled Trandolapril. Trandolapril is an orally active inhibitor of angiotensin converting enzyme (ACE) for hypertension and congestive heart failure (CHF). | |||
TMIJ-0176 |
Perindopril-d4
|
||
Perindopril-d4 是 Perindopril 的氘代化合物。Perindopril 的 CAS 号为 95153-31-4。Perindoprilat 是一种血管紧张素转换酶抑制剂。 | |||
TMIJ-0177 |
Perindoprilat-d4
|
||
Perindoprilat-d4 是 Perindoprilat 的氘代化合物。Perindoprilat 的 CAS 号为 95153-31-4。Perindoprilat 是一种血管紧张素转换酶抑制剂。 | |||
T71065 |
Quinapril-d5
|
||
Quinapril-d5 is intended for use as an internal standard for the quantification of quinapril by GC- or LC-MS. Quinapril is a prodrug form of the angiotensin converting enzyme (ACE) inhibitor quinaprilat. In vivo, quinapril reduces mean arterial pressure in renal hypertensive and spontaneously hypertensive rats. It inhibits angiotensin I-induced pressor responses in normotensive rats and dogs. Quinapril prevents left ventricular heart failure in CHF 14.6 cardiomyopathic hamsters. Formulations con... | |||
T71205 |
Fosinopril-d7 sodium salt
|
||
Fosinopril-d7 is intended for use as an internal standard for the quantification of fosinopril by GC- or LC-MS. Fosinopril is a prodrug form of the angiotensin-converting enzyme inhibitor fosinoprilat. Oral administration of fosinopril inhibits angiotensin I-induced pressor responses in normotensive rats, dogs, and monkeys when administered at doses of 15, 15, and 10 µmol/kg, respectively. Fosinopril reduces fractional shortening and decreases left ventricular size in a porcine model of congesti... | |||
TMIJ-0253 |
Benazepril-d5 HCl
|
||
Benazepril-d5 HCl 是 Benazepril HCl 的氘代化合物。Benazepril HCl 的 CAS 号为 86541-74-4。Benazepril hydrochloride 是一种血管紧张素转化酶(ACE)抑制剂,能够作用于高血压。 | |||
T70883 |
Moexipril-d5
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Moexipril-d5 intended for use as an internal standard for the quantification of moexipril by GC- or LC-MS. Moexipril is a prodrug form of the angiotensin converting enzyme (ACE) inhibitor moexiprilat. It is converted to moexiprilat in vivo by side chain ester hydrolysis. Moexipril inhibits ACE in a cell-free assay (IC50 = 2.7 µM for the rabbit enzyme). It also inhibits phosphodiesterase 4 (IC50s = 38, 160, and 230 µM for PDE4B2, PDE4A5 and PDE4D5, respectively). Moexipril (0.1-30 mg/kg per day) ... |