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Search Results for " amyloid "

Targets Recommended: Beta Amyloid Beta Amyloid

305

抑制剂 & 化合物

34

天然产物

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化合物库

66

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同位素标记化合物

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Cat. No.	Product Name
L1310	细胞骨架化合物库		759 compounds
	759 种细胞骨架相关的化合物，可以用于高通量和高内涵筛选；
L9840	抗阿尔茨海默症化合物库		986 compounds
	986 种阿尔茨海默症相关的化合物集合，可用于高通量和高内涵筛选；

化合物库

细胞骨架化合物库

Cat.No: L1310

Compounds: 759

抗阿尔茨海默症化合物库

Cat.No: L9840

Compounds: 986

Cat. No.	Product Name	Target	Signaling Pathways
TP1214L	β-Amyloid 15-21 acetate Beta-Amyloid (15-21) acetate	Beta Amyloid	Neuroscience
	β-Amyloid 15-21 acetate (Beta-Amyloid(15-21) acetate) 是 Amyloid-β 肽的片段，可用于神经系统疾病的研究。该片段参与β折叠形成。
TP1229	β-Amyloid (1-15) Amyloid β-Protein (1-15)	Beta Amyloid	Neuroscience
	β-Amyloid (1-15) (Amyloid β-Protein (1-15)) 是 β-淀粉样蛋白片段，可用于研究阿尔茨海默病。
T7562	β-Amyloid (31-35) 异亮氨酰-异亮氨酰-甘氨酰-亮氨酰-蛋氨酸,β-Amyloid 31-35(TFA),β-Amyloid 31-35	Beta Amyloid	Neuroscience
	β-Amyloid (31-35) (β-Amyloid 31-35) 是一种天然 Amyloid-β 肽的最短序列，具有神经毒性。
T14284	β-Amyloid (25-35) β-Amyloid peptide(25-35),Aβ25-35,BETA-淀粉样蛋白片断25-35,Amyloid beta-peptide(25-35)	Beta Amyloid	Neuroscience
	β-Amyloid (25-35) (Aβ25-35) 是一种阿尔茨海默氏淀粉样蛋白β肽的Aβ(25-35) 片段，在培养细胞中显示出神经毒性作用。
TP1786L	Amyloid β-Protein 10-20 acetate Amyloid β-Protein 10-20 acetate(152286-31-2 free base)	Beta Amyloid	Neuroscience
	Amyloid β-Protein 10-20 acetate (Amyloid β-Protein 10-20 acetate (152286-31-2 free base)) 是 Amyloid-β 肽的片段，可能用于神经系统疾病的研究。Amyloid β 蛋白片段含有 α-分泌酶加工位点（Lys16-Leu17 键）。它还包含负责与小胶质细胞结合的 HHQK 结构域（残基 13-16）。
T35499	β-Amyloid (1-42), (rat/mouse) (TFA) Amyloid β-peptide (1-42) (human) TFA,166090-74-0 TFA
	β-Amyloid (1-42), (rat/mouse) (TFA) 是由 42 个氨基酸组成的多肽片段，可用于研究阿尔茨海默症。
TP1007L	β-Amyloid (1-42), acetate (human) β-Amyloid (1-42), human acetate (107761-42-2 Free base)
	β-Amyloid (1-42), acetate (human) 是由 42 个氨基酸组成的肽，是 β-Amyloid 的一部分，常用于阿尔茨海默病造模。
T14283	amyloid P-IN-1	Beta Amyloid	Neuroscience
	amyloid P-IN-1 可用于研究血清淀粉样蛋白 P 成分耗尽的疾病，例如阿尔茨海默病、淀粉样变性、骨关节炎和 2 型糖尿病。
TP1359L	Amyloid β Peptide (42-1)(human) acetate Amyloid β Peptide (42-1)(human) acetate(317366-82-8 free base)	Beta Amyloid	Neuroscience
	Amyloid β Peptide (42-1)(human) acetate 是淀粉样蛋白 β 肽 (1-42) 的无活性形式。Amyloid β Peptide (42-1)(human) acetate 是由 42 个氨基酸组成的肽，其在阿尔茨海默病的发病机制中起关键作用。
TP1866L	β-amyloid 1-11 acetate(190436-05-6 free base)	Beta Amyloid	Neuroscience
	β-amyloid 1-11 acetate(190436-05-6 free base) 是 Amyloid-β 肽的片段，可用于神经系统疾病的研究。
TP1228	β-Amyloid (1-16) Amyloid β-Protein (1-16),β-Amyloid 1-16
	β-Amyloid (1-16) is an amyloidogenic protein fragment with a sequence derived from β-amyloid. It exhibits the ability to bind to metal ions, indicating its involvement in metal-binding processes. β-Amyloid, a peptide, is responsible for the formation of amyloid plaques in the brains of individuals affected by Alzheimer's disease (AD).
TP1225	β-Amyloid (22-35) β-Amyloid 22-35,Amyloid β-Protein (22-35)
	β-Amyloid (22-35) is a 14-aa peptide, shows aggregates and induces neurotoxicity in the hippocampal cells. Beta amyloid (22-35) is a synthetic truncated fragment of beta-amyloid peptide.
TP1231	β-Amyloid (29-40) Amyloid beta-protein(29-40),β-Amyloid 29-40
	β-Amyloid (29-40) is a fragment of Amyloid-β peptide.Alzheimer's beta amyloid peptide (29-40/42) C-terminal fragments have physical and chemical properties related to those of fusion peptides of viral proteins. The fusion of liposomes can be induced by th
TP1227	β-Amyloid (12-28) β-amyloid 12-28,Amyloid β-Protein (12-28)
	Amyloid β-peptide fragment; minimum section required to bind to brain proteins. Binds with high affinity to α7-nicotinic ACh receptors, and impairs memory retention following central administration in mice in vivo.
TP1719	β-Amyloid (33-40) β-Amyloid 33-40
	β-Amyloid (33-40) is a peptide consisting of amino acid of 33 to 40 of beta amyloid protein.
TP1586	β-Amyloid (35-42) β-Amyloid 35-42
	β-Amyloid (35-42) is a peptide consisting of amino acid of 35 to 42 of beta amyloid protein.
TP1500	β-Amyloid (1-17) β-Amyloid 1-17
	This synthetic peptide consists of amino acids 1 to 17 of beta amyloid protein. This peptide can be employed in beta amyloid solubility studies.
TP1673	β-Amyloid (11-22) β-Amyloid 11-22
	β-Amyloid (11-22) is a peptide fragment of β-Amyloid.Beta-amyloid peptide (Abeta), the major constituent of amyloid plaques in the brains of Alzheimer’s patients, is thought to be the cause of Alzheimer’s Disease (AD). AD is the most common neurodegenerat
TP1214	β-Amyloid 15-21 Beta-Amyloid (15-21)
	β-amyloid (15-21) is a fragment of Amyloid-β peptide, maybe used in the research of neurological disease. This fragment is involved in beta sheet formation.
TP1494	β-Amyloid (4-10) β-Amyloid 4-10
	Antibodies corresponding to beta-amyloid (4-10) are effective in vivo inhibitors of cytotoxicity, amyloid plaque formation and special memory disturbances in mice. This peptide does not elicit an inflammatory response.
TP1645	β-Amyloid (1-9) β-Amyloid 1-9
	This is an N-terminal fragment of beta amyloid. It consists of amino acid residues 1 to 9. Truncated beta amyloid peptide (10-40) still forms amyloid fibrils and shows fibril polymorphism.
TP1303	β-Amyloid (1-40) β-Amyloid 1-40
	Amyloid β1-40 is one of the fragments generated after cleavage of the amyloid peptide precursor protein by β and γ secretases.
TP1544	β-Amyloid (22-40) β-Amyloid 22-40
	This synthetic peptide consists of amino acids 22 to 40 of beta amyloid protein. This peptide sequence is often used in beta amyloid structure and aggregation studies.
TP1538	β-Amyloid (1-20) β-Amyloid 1-20
	This synthetic peptide consists of amino acids 1 to 20 of beta amyloid protein.
TP1599	β-Amyloid (1-34) β-Amyloid 1-34
	This is a fragment of beta-amyloid peptide. It has amino acids 1 through 34.
TP1633	β-Amyloid (18-28) β-Amyloid 18-28
	Intracerebroventricular administration of synthetic peptides Beta-amyloid (12-20), (12-28), and (18-28) causes amnesia in mice. These peptides have only amino acid residues VFF at position 18 to 20 in common, suggesting the amnestic effect of the triad.
TP1786	β-Amyloid (10-20) Amyloid β-Protein 10-20
	Amyloid β-Protein (10-20) is a fragment of Amyloid-β peptide, maybe used in the research of neurological disease.Amyloid β protein fragment containing the α-secretase processing site (Lys16-Leu17 bond). It also contains the HHQK domain (residues 13-16) re
TP1226	β-Amyloid (1-28) Amyloid β-Protein (1-28),β-Amyloid 1-28
	β-Amyloid (1-28) is a β-Amyloid protein fragment involved in metal binding.
TP1692	β-Amyloid (13-27) β-Amyloid 13-27
	β-Amyloid (13-27) is a peptide consisting of amino acid of 13 to 27 of beta amyloid protein. This synthetic peptide consists of amino acids 26 to 40 of beta amyloid protein. It can be used to study the kinetics of beta amyloid formation.
TP1866	β-Amyloid (1-11) β-amyloid 1-11
	Anionic interaction of Beta-amyloid (1-11) with Factor XII is suspected to cause massive activation of the C4 (complement 4) system in the cerebrospinal fluid of Alzheimer’s disease patients.
TP1480	β-Amyloid (12-20) β-Amyloid 12-20
	β-Amyloid (12-20) is a peptide fragment of β-Amyloid.Thsis peptide contain the amino acid residues VFF at position (18-20), suggesting that this triad has amnestic effects.
T37369	Amyloid-β (1-8, A2V) Peptide Amyloid-β (1-8, A2V) Peptide	Others	Others
	Amyloid-β (1-8, A2V) is a truncated form of amyloid-β (Aβ) that contains a valine to alanine substitution at position 2 of the Aβ numbering convention (Aβ A2V), which corresponds to position 673 of the amyloid precursor protein (APP) numbering convention (APP A673V). An Aβ (1-40) (Aβ40) A2V peptide increases the production of Aβ and the rate and amount of amyloid fibril formation in vitro, effects that can be reduced by coincubation with wild-type Aβ40. Aβ40 and Aβ42 levels are increased in CHO ...
TP1007	β-Amyloid (1-42), human 大豆肽,β-Amyloid (1-42), human,Amyloid β-Peptide (1-42) human	Beta Amyloid	Neuroscience
	β-Amyloid (1-42), human 是一种由 42 个氨基酸组成的肽，在阿尔茨海默病的发病机制中起关键作用。
TP1359	β-Amyloid (42-1), human Amyloid β Peptide (42-1)(human)
	β-Amyloid (42-1), human is the inactive form of Amyloid β Peptide (1-42) which plays a key role in the pathogenesis of Alzheimer disease.
TP1230	β-Amyloid (1-42), (rat/mouse) β-Amyloid (1-42), rat,Amyloid β-peptide (1-42) (rat)
	Amyloid (1-42), rat is a polypeptide composed of 42 amino acids. It is toxic to hippocampal slices and can be used in the study of alzheimer's disease.
T80037	5-FAM-β-Amyloid (1-28) 5-FAM-Amyloid β-protein (1-28)
	5-FAM-β-Amyloid (1-28) 为β-Amyloid (1-28) 分子的荧光标记形式。
T80035	Biotin-β-Amyloid (1-42), human TFA Biotin-amyloid β-peptide (1-42) (human) TFA
	Biotin-β-Amyloid (1-42), human TFA（Biotin-Amyloid β-Peptide (1-42) (human) TFA）是一种标记有生物素的β-Amyloid (1-42)肽，由42个氨基酸构成，对阿尔茨海默病的发病机理有重要作用。
TP1441	β-Amyloid (1-40) (rat) Amyloid β-peptide (1-40) rat,β淀粉样肽(1-40)(鼠)
	Rat form of the beta-Amyloid (1-40) peptide
TP2171	β-amyloid (12-28) (TFA) (107015-83-8 free base) Amyloid β-Protein (12-28) (TFA),β-amyloid (12-28) (TFA)	Others	Others
	β-amyloid (12-28) TFA, a peptide fragment of β-amyloid protein (β1-42), is the major component of senile plaque cores. β-amyloid (12-28) has aggregation properties and the potential for Alzheimer’s disease research.
T39285	Biotin-β-Amyloid (1-40)
	Biotin-β-Amyloid (1-40) is a N-terminal-labelled biotinylated amyloid- -(1-40) peptide.
T7680	GSNKGAIIGLM(131602-53-4(free base)) Amyloid beta-peptide(25-35),BETA-淀粉样蛋白片断25-35	Beta Amyloid	Neuroscience
	GSNKGAIIGLM(131602-53-4(free base)) (Amyloid beta-peptide(25-35)) 是阿尔茨海默病淀粉样蛋白 β-肽的片段 Aβ(25-35)。
T37768	β-Amyloid (1-37) (human)
	β-Amyloid (1-37) (human) 与阿尔茨海默病的精神状态有潜在关联。
T38149	β-Amyloid (1-43)(human)
	The amyloid β-protein is a 39- to 43-amino acid polypeptide that is the primary constituent of senile plaques and cerebrovascular deposits in Alzheimer's disease and Down's syndrome. Additionally it acts as an inhibitor of the ubiquitin-dependent protein degradation in vitro.
TP1655	β-Amyloid Protein Precursor 770 (135-155) β-Amyloid Protein Precursor 770 135-155
	Beta-Amyloid Protein Precursor 770 (135-155)Aβ Protein Precursor 770 (135-155)
T35498	β-Amyloid (1-14),mouse,rat
	β-Amyloid (1-14),mouse,rat is a 1 to 14 fragment of Amyloid-β peptide. β-Amyloid (1-14),mouse,rat is produced through the proteolytic processing of a transmembrane protein, amyloid precursor protein (APP), by β- and γ-secretases. β-Amyloid (1-14),mouse,rat accumulation in the brain is proposed to be an early toxic event in the pathogenesis of Alzheimer’s disease, which is the most common form of dementia associated with plaques and tangles in the brain[1]. [1]. Chen GF, et al. Amyloid beta: stru...
T39302	β-Amyloid (1-38), mouse, rat
	β-Amyloid (1-38), derived from mice and rats, is a chemical compound comprising 38 amino acids, specifically residues 1-38 of the Aβ peptide. Notably, it serves as the primary constituent of amyloid plaques associated with Alzheimer's disease.
T37368	Amyloid-β (1-8) Peptide	Others	Others
	Amyloid-β (1-8) is a wild-type control for the mutation-containing amyloid-β (1-8, A2V) peptide .
T39146	β-Amyloid (1-40), FAM-labeled
	β-Amyloid (1-40), FAM-labeled is a FAM fluorescently-labelled β-Amyloid (1-40) peptide (λ ex = 492 nm and λ em = 518 nm).
T37370	Amyloid-β (25-35) Peptide (human) (trifluoroacetate salt)
	Amyloid-β (25-35) (Aβ (25-35)) is an 11-residue fragment of the Aβ protein that retains the physical and biological characteristics of the full length peptide. It forms fibrils that react to thioflavin T and Congo red and are organized in a cross-β arrangement of β-strands similar to Aβ (1-40) and Aβ (1-42) fibrils. Aggregated Aβ (25-35) decreases the viability of rat adrenal PC12 cells. It also decreases the viability of primary rat cortical neurons at concentrations ranging from 1 nM to 30 μM....
T37367	Amyloid-β (1-42) Peptide (trifluoroacetate salt)	Others	Others
	Amyloid-β (1-42) (Aβ42) is a neurotoxic 42-amino acid protein fragment found in amyloid plaques in postmortem cerebral cortex from patients with Alzheimer's disease.1,2,3Aggregation of Aβ42 results in the formation of neurotoxic fibrils or globular oligomers.1Aβ42 accumulates in the brain of many transgenic mouse models of Alzheimer's disease and, in many models, the onset of amyloid deposition positively correlates with deficits in spatial learning and memory.4 1.Wolfe, M.S.Therapeutic strategi...

化合物

β-Amyloid 15-21 acetate

Cat.No: TP1214L

Synonym: Beta-Amyloid (15-21) acetate

Target: Beta Amyloid

β-Amyloid (1-15)

Cat.No: TP1229

Synonym: Amyloid β-Protein (1-15)

Target: Beta Amyloid

β-Amyloid (31-35)

Cat.No: T7562

Synonym: 异亮氨酰-异亮氨酰-甘氨酰-亮氨酰-蛋氨酸,β-Amyloid 31-35(TFA),β-Amyloid 31-35

Target: Beta Amyloid

β-Amyloid (25-35)

Cat.No: T14284

Synonym: β-Amyloid peptide(25-35),Aβ25-35,BETA-淀粉样蛋白片断25-35,Amyloid beta-peptide(25-35)

Target: Beta Amyloid

Amyloid β-Protein 10-20 acetate

Cat.No: TP1786L

Synonym: Amyloid β-Protein 10-20 acetate(152286-31-2 free base)

Target: Beta Amyloid

β-Amyloid (1-42), (rat/mouse) (TFA)

Cat.No: T35499

Synonym: Amyloid β-peptide (1-42) (human) TFA,166090-74-0 TFA

β-Amyloid (1-42), acetate (human)

Cat.No: TP1007L

Synonym: β-Amyloid (1-42), human acetate (107761-42-2 Free base)

amyloid P-IN-1

Cat.No: T14283

Target: Beta Amyloid

Amyloid β Peptide (42-1)(human) acetate

Cat.No: TP1359L

Synonym: Amyloid β Peptide (42-1)(human) acetate(317366-82-8 free base)

Target: Beta Amyloid

β-amyloid 1-11 acetate(190436-05-6 free base)

Cat.No: TP1866L

Target: Beta Amyloid

β-Amyloid (1-16)

Cat.No: TP1228

Synonym: Amyloid β-Protein (1-16),β-Amyloid 1-16

β-Amyloid (22-35)

Cat.No: TP1225

Synonym: β-Amyloid 22-35,Amyloid β-Protein (22-35)

β-Amyloid (29-40)

Cat.No: TP1231

Synonym: Amyloid beta-protein(29-40),β-Amyloid 29-40

β-Amyloid (12-28)

Cat.No: TP1227

Synonym: β-amyloid 12-28,Amyloid β-Protein (12-28)

β-Amyloid (33-40)

Cat.No: TP1719

Synonym: β-Amyloid 33-40

β-Amyloid (35-42)

Cat.No: TP1586

Synonym: β-Amyloid 35-42

β-Amyloid (1-17)

Cat.No: TP1500

Synonym: β-Amyloid 1-17

β-Amyloid (11-22)

Cat.No: TP1673

Synonym: β-Amyloid 11-22

β-Amyloid 15-21

Cat.No: TP1214

Synonym: Beta-Amyloid (15-21)

β-Amyloid (4-10)

Cat.No: TP1494

Synonym: β-Amyloid 4-10

β-Amyloid (1-9)

Cat.No: TP1645

Synonym: β-Amyloid 1-9

β-Amyloid (1-40)

Cat.No: TP1303

Synonym: β-Amyloid 1-40

β-Amyloid (22-40)

Cat.No: TP1544

Synonym: β-Amyloid 22-40

β-Amyloid (1-20)

Cat.No: TP1538

Synonym: β-Amyloid 1-20

β-Amyloid (1-34)

Cat.No: TP1599

Synonym: β-Amyloid 1-34

β-Amyloid (18-28)

Cat.No: TP1633

Synonym: β-Amyloid 18-28

β-Amyloid (10-20)

Cat.No: TP1786

Synonym: Amyloid β-Protein 10-20

β-Amyloid (1-28)

Cat.No: TP1226

Synonym: Amyloid β-Protein (1-28),β-Amyloid 1-28

β-Amyloid (13-27)

Cat.No: TP1692

Synonym: β-Amyloid 13-27

β-Amyloid (1-11)

Cat.No: TP1866

Synonym: β-amyloid 1-11

β-Amyloid (12-20)

Cat.No: TP1480

Synonym: β-Amyloid 12-20

Amyloid-β (1-8, A2V) Peptide

Cat.No: T37369

Synonym: Amyloid-β (1-8, A2V) Peptide

Target: Others

β-Amyloid (1-42), human

Cat.No: TP1007

Synonym: 大豆肽,β-Amyloid (1-42), human,Amyloid β-Peptide (1-42) human

Target: Beta Amyloid

β-Amyloid (42-1), human

Cat.No: TP1359

Synonym: Amyloid β Peptide (42-1)(human)

β-Amyloid (1-42), (rat/mouse)

Cat.No: TP1230

Synonym: β-Amyloid (1-42), rat,Amyloid β-peptide (1-42) (rat)

5-FAM-β-Amyloid (1-28)

Cat.No: T80037

Synonym: 5-FAM-Amyloid β-protein (1-28)

Biotin-β-Amyloid (1-42), human TFA

Cat.No: T80035

Synonym: Biotin-amyloid β-peptide (1-42) (human) TFA

β-Amyloid (1-40) (rat)

Cat.No: TP1441

Synonym: Amyloid β-peptide (1-40) rat,β淀粉样肽(1-40)(鼠)

β-amyloid (12-28) (TFA) (107015-83-8 free base)

Cat.No: TP2171

Synonym: Amyloid β-Protein (12-28) (TFA),β-amyloid (12-28) (TFA)

Target: Others

Biotin-β-Amyloid (1-40)

Cat.No: T39285

GSNKGAIIGLM(131602-53-4(free base))

Cat.No: T7680

Synonym: Amyloid beta-peptide(25-35),BETA-淀粉样蛋白片断25-35

Target: Beta Amyloid

β-Amyloid (1-37) (human)

Cat.No: T37768

β-Amyloid (1-43)(human)

Cat.No: T38149

β-Amyloid Protein Precursor 770 (135-155)

Cat.No: TP1655

Synonym: β-Amyloid Protein Precursor 770 135-155

β-Amyloid (1-14),mouse,rat

Cat.No: T35498

β-Amyloid (1-38), mouse, rat

Cat.No: T39302

Amyloid-β (1-8) Peptide

Cat.No: T37368

Target: Others

β-Amyloid (1-40), FAM-labeled

Cat.No: T39146

Amyloid-β (25-35) Peptide (human) (trifluoroacetate salt)

Cat.No: T37370

Amyloid-β (1-42) Peptide (trifluoroacetate salt)

Cat.No: T37367

Target: Others

Cat. No.	Product Name	Target	Signaling Pathways
T2212	Geniposide 栀子苷,京尼平甙	Beta Amyloid; Influenza Virus	Microbiology/Virology; Neuroscience
	Geniposide 是从栀子花中提取的一种环烯醚萜甙，具有如神经保护、抗糖尿病、抗增殖和抗氧化多种生物活性。它可调节 Nrf2 易位。
TN6919	Methyl tridecanoate	Beta Amyloid; AChE	Neuroscience
	Methyl tridecanoate 能够适度抑制 β-淀粉样蛋白聚集，弱抑制乙酰胆碱酯酶。
T8012	Scyllo-Inositol Scyllitol,鲨肌醇	Beta Amyloid; Endogenous Metabolite	Metabolism; Neuroscience
	Scyllo-Inositol (Scyllitol) 是淀粉样抑制剂，能够抑制 α-突触核蛋白聚集。它在体外能够稳定非纤维状无毒形式的淀粉样蛋白-β 肽，逆转阿尔茨海默病小鼠模型的认知缺陷，抑制突触毒性和淀粉样斑块。
T3914	Saikosaponin C 柴胡皂苷C,柴胡皂苷 C	Beta Amyloid; Caspase	Apoptosis; Neuroscience; Proteases/Proteasome
	Saikosaponin C 是一种柴胡中的活性成分，能够抑制 Aβ1-40 和 Aβ1-42 的释放，抑制异常 tau 蛋白的磷酸化，但对 BACE1 的活性和表达无作用。它在阿尔滋海默症中主要靶作用于amyloid beta 和tau 蛋白。
T4S0350	Licochalcone B 甘草查尔酮 B,甘草查尔酮B	Beta Amyloid; Others	Neuroscience; Others
	Licochalcone B 是从Glycyrrhiza inflate 根中提取的。它能够抑制淀粉样蛋白 β 自聚集作用 (IC50=2.16 μM) ，分解预先形成的 Aβ42原纤维，并通过螯合金属离子抑制金属诱导的 Aβ42聚集。
TMS1461	Qingyangshengenin B 青阳参甙元B,青阳参苷元B,Otophylloside B	Beta Amyloid	Neuroscience
	Qingyangshengenin B (Otophylloside B) 是一种分离自 Qingyangshen 的 C-21 甾体苷。它能够在 mRNA 水平上抑制 Aβ 的表达来减少 Aβ 的沉积，对 Aβ 的毒性有保护作用。它具有抗癫痫作用。
T0795	Rutin Quercetin 3-O-rutinoside,芦丁,Rutoside	Beta Amyloid; Prostaglandin Receptor; Autophagy	Autophagy; GPCR/G Protein; Immunology/Inflammation; Neuroscience
	Rutin (Quercetin 3-O-rutinoside) 属于黄酮类天然产物，具有血脑屏障渗透性。Rutin 具有广泛的生物活性，包括抗氧化、抗炎、抗肿瘤、降血糖、神经保护、抗菌、抗衰老等等。
T22417	Rutin hydrate 芦丁,Rutoside,Sophorin,Quercetin-3-O-rutinoside	Beta Amyloid; Others; Autophagy	Autophagy; Neuroscience; Others
	Rutin hydrate (Sophorin) 是一种广泛存在于多种植物中的黄酮类天然产物，具有降糖、抗炎、抗氧化、神经保护、肾脏保护、肝脏保护和降低 Aβ 低聚物活性等多种生物活性。它能穿过血脑屏障，通过抑制细胞凋亡、线粒体功能紊乱和氧化应激抑制万古霉素诱导的肾小管细胞凋亡。
T1686	Hematoxylin 苏木精,Hydroxybrazilin,Natural Black 1,Haematoxylin	Beta Amyloid; Others	Neuroscience; Others
	Hematoxylin (Natural Black 1) 是一种天然存在的类黄酮化合物，衍生自木柴树Haematoxylon campechianum。它是一种组织学上的核染色剂，也是一种有效的Aβ42原纤维形成的抑制剂，IC50=1.6 µM。
T6S1918	Schisantherin B Gomisin-B,Wuweizi ester-B,五味子酯乙,Schizantherin-B	Beta Amyloid; Others	Neuroscience; Others
	Schisantherin B (Schizantherin-B) 是一种天然产物。
T0883	Tramiprosate Homotaurine,3-Amino-1-propanesulfonic acid,Alzhemed,高牛黄酸	Beta Amyloid; GABA Receptor	Membrane transporter/Ion channel; Neuroscience
	Tramiprosate (Alzhemed) 是一种具有口服活性的、可透过血脑屏障的天然氨基酸，存在于各种红色海藻中，能够可溶性 Aβ 结合并以非原纤维形式维持 Aβ。它是一种 GABA 类似物，具有神经保护，抗惊厥和抗高血压的活性。
T2961	Notoginsenoside R1 Sanqi glucoside R1,Sanchinoside R1,三七皂苷R1	Apoptosis; ERK; Beta Amyloid	Apoptosis; MAPK; Neuroscience
	Notoginsenoside R1 (Sanchinoside R1) 属于皂苷类天然产物，是三七的主要活性单体。Notoginsenoside R1 具有心血管保护、神经保护、肝脏保护、抗肿瘤、免疫调节等活性。
T2872	Ginsenoside Re 人参皂苷 Re,Ginsenoside B2,Panaxoside Re,Chikusetsusaponin Ivc,Sanchinoside Re,人参皂苷Re	Beta Amyloid; NF-κB; Endogenous Metabolite; JNK	MAPK; Metabolism; Neuroscience; NF-κB
	Ginsenoside Re (Ginsenoside B2) 是一种人参提取物，可降低 β-淀粉样蛋白 (Aβ)，还通过抑制 JNK 和 NF-κB 发挥抗炎作用。
T2777	Ginsenoside Rg1 Sanchinoside C1,Panaxoside Rg1,Sanchinoside Rg1,人参皂苷Rg1,Panaxoside A,人参皂苷 Rg1,Ginsenoside A2	Apoptosis; Beta Amyloid; NF-κB	Apoptosis; Neuroscience; NF-κB
	Ginsenoside Rg1 (Panaxoside Rg1) 是人参的主要活性成分之一，可减少NF-κB 核易位。它改善认知功能受损，通过降低大脑Aβ水平来发挥作用。
T2873	Ginsenoside Rg2 Chikusetsusaponin I,Panaxoside Rg2,人参皂苷Rg2,Prosapogenin C2,(20S)Ginsenoside Rg2,人参皂苷 Rg2	Beta Amyloid; GSK-3; NF-κB	Neuroscience; NF-κB; PI3K/Akt/mTOR signaling; Stem Cells
	Ginsenoside Rg2 (Chikusetsusaponin I) 是一种人参的主要活性成分。它能够降低Aβ1-42积聚，抑制脂多糖介导的VCAM-1和ICAM-1表达的增加。
T3402	20(S)-Ginsenoside Rg3 20(S)-人参皂苷 Rg3,人参皂苷 Rg3,20(S)-Ginsenoside-Rg3,Rg3,20S-Ginsenoside Rg3,Ginsenoside Rg3,S-Ginsenoside Rg3	EGFR; Beta Amyloid; Potassium Channel; NF-κB; COX; Sodium Channel; Endogenous Metabolite	Angiogenesis; Immunology/Inflammation; JAK/STAT signaling; Membrane transporter/Ion channel; Metabolism; Neuroscience; NF-κB; Tyrosine Kinase/Adaptors
	20(S)-Ginsenoside Rg3 (Rg3) 是红参的主要成分，通过抑制肿瘤细胞的粘附和侵袭来抑制肿瘤细胞肺转移。它抑制Na+和hKv1.4通道，IC50分别为 32.2±4.5 和 32.6±2.2 μM。它还抑制Aβ，NF-κB 活性和COX-2表达，抑制人脐静脉内皮细胞的增殖并具有抗血管生成活性。
TN1653	Fustin	ERK; Beta Amyloid; AChR	MAPK; Neuroscience
	Fustin 是植物漆树 (Rhus verniciflua Stokes) 的植物性黄烷醇成分。 Fustin 对 6-羟基多巴胺诱导的神经元细胞死亡具有保护作用。
TN1736	Hibifolin 棉皮素-8-O-Β-D-葡萄糖醛酸苷,棉花皮素-8-O-葡萄糖醛酸苷	Adenosine deaminase	Metabolism
	Hibifolin 是一种黄酮醇糖苷，是潜在的腺苷脱氨酶抑制剂。它可以保护神经元免受 beta-淀粉样蛋白诱导的毒性。
TN1216	2-O-Acetyl-20-hydroxyecdysone 20-Hydroxyeedysone 2-acetate	Beta Amyloid; Others	Neuroscience; Others
	2-O-Acetyl-20-hydroxyecdysone 是存在于昆虫和陆生植物中的一种蜕皮激素，2-O-Acetyl-20-hydroxyecdysone 对 amyloid-β42 诱导的细胞毒性有抑制作用，能够通过促进纤维发生减少 Aβ 寡聚物的形成，将 Aβ 寡聚物转变为低毒性纤维。
T2987	(-)-Epigallocatechin 表没食子儿茶素,(-)-表没食子儿茶素,l-Epigallocatechin,Epigallocatechin,EGC	MMP; Autophagy	Autophagy; Proteases/Proteasome
	(-)-Epigallocatechin (Epigallocatechin) 是绿茶中含量最丰富的黄酮类天然产物，可与未折叠的天然多肽结合，阻止转化为淀粉样蛋白原纤维。
T3769	Tenuifolin	Others; Beta-Secretase; AChE	Neuroscience; Others
	Tenuifolin 是一种从远志中分离出的三萜，能够抑制β-secretase 以减少 Aβ 蛋白分泌，具有神经保护作用。它可通过降低 AChE 活性来改善衰老小鼠的学习和记忆能力，有潜力用于阿尔茨海默氏病的研究。
TN2190	Scoulerine	Apoptosis; Beta-Secretase; BACE; Parasite	Apoptosis; Microbiology/Virology; Neuroscience
	Scoulerine 是抗有丝分裂化合物。它抑制细胞增殖，阻止细胞周期，并诱导癌细胞凋亡。它也是BACE1(淀粉样前体蛋白裂解酶 1) 的抑制剂。
TN1038	Galgravin	Apoptosis	Apoptosis
	Galgravin 是望春花中的一种天然产物，具有抗炎和体外细胞毒活性，能诱导白血病细胞凋亡。
TN1341	8-Deoxygartanin 8-脱氧藤黄苷	Beta Amyloid; NF-κB; Parasite	Microbiology/Virology; Neuroscience; NF-κB
	8-Deoxygartanin 是山竹果中的异戊烯化呫吨酮。它是丁基胆碱酯酶选择性抑制剂，对阿尔茨海默病 (AD) 具有多功能活性，可能是有希望治疗 AD 的化合物。
TN4368	Kaempferol-3,7-di-O-β-glucoside Kaempferol 3,7-di-O-glucoside	Glucosidase; Amylase	Metabolism
	Kaempferol-3,7-di-O-β-glucoside (Kaempferol 3,7-diglucoside) 是一种来自 Morettia philaena 的黄酮醇，对 α-淀粉酶 (α-amylase)、α-葡萄糖苷酶 (α-glucosidase) 和乙酰胆碱酯酶 (Acetylcholinesterase) 具有抑制作用。Kaempferol-3,7-di-O-β-glucoside 具有神经保护活性，可减缓分化神经元细胞 SH-SY5Y 免受 Amyloid β 肽诱导的损伤。Kaempferol-3,7-di-O-β-glucoside 可用于研究阿尔茨海默氏症类的神经系统疾病。
TL0007	Bisdemethoxycurcumin 双去甲氧基姜黄素,Curcumin III,Didemethoxycurcumin	Epigenetic Reader Domain; Wnt/beta-catenin	Chromatin/Epigenetic; Cytoskeletal Signaling; Stem Cells
	Bisdemethoxycurcumin (Curcumin III) 是一种具有抗炎及抗氧化作用的姜黄素。
TN1420	Bacopaside I	Others	Others
	Bacopaside I 是一种皂苷，分离自 Bacopa monniera 中，具有抗氧化活性和清除自由基的功能，有抗抑郁作用。
T32614	L-Clausenamide (-)-Clausenamide	Microtubule Associated	Cytoskeletal Signaling
	L-Clausenamide 是从黄皮 (Clausena lansium (Lour) skeels) 的树叶中提取出来的生物碱，可用于提高认知功能。L-Clausenamide 对β-淀粉样蛋白 (Aβ) 毒性有抑制作用，通过抑制 tau 蛋白磷酸化阻止神经纤维缠结的形成。L-Clausenamide 具有神经保护活性，可用于调节 Aβ25-35 引发的刺激。L-Clausenamide 可用于研究阿尔兹海默症类的神经系统疾病。
T2S0843	Negletein 黄芩素-7-甲醚,7-O-Methylbaicalein,Baicalein-7-methylether	IL Receptor; TNF; NOS; Interleukin	Apoptosis; Immunology/Inflammation
	Negletein (7-O-Methylbaicalein) 一种神经保护剂，可增强神经生长因子的作用并诱导 PC12 细胞中的神经突生长。它通过抑制TNF-α和IL-1β表现出抗炎活性，其 IC50值分别为 16.4 和 10.8 μM。它还具有抗菌、抗缺氧和抗阿尔茨海默病活性。
T79968	Coumarinic acid	Others	Others
	Coumarinic acid为具有脑穿透性的双重功能抑制剂，能够抑制AChE和β-amyloid，适用于开发治疗阿尔茨海默病的药物研究。
T37957	Setosusin	Others	Others
	Setosusin is a meroterpenoid fungal metabolite originally isolated from C. setosus. It reduces neurotoxicity induced by amyloid-β (Aβ) aggregates in PC12 cells (EC50 = 112.6 μM). In vivo, setosusin (30 mg/kg) induces tremors in mice.
TN3618	Cedrin	Beta Amyloid; BCL; Caspase	Apoptosis; Neuroscience; Proteases/Proteasome
	Cedrin has protective effects on PC12 cells against the neurotoxicity induced by amyloid β1-42, the protective effect is related to the inhibition of oxidative stress, improvement of mitochondrial dysfunction and suppression of apoptosis.
T83407	2',3'-Dihydroxy-4',6'-dimethoxychalcone
	2',3'-Dihydroxy-4',6'-dimethoxychalcone 能够抑制β淀粉样蛋白(Aβ42)的纤维化与聚集，并具有口服活性，在大脑中可进行检测。
T38108	Fulvic Acid	Antioxidant; PDE	Metabolism; oxidation-reduction
	Fulvic Acid 是一种来自土壤、沉积物或水生环境中微生物产生的腐殖质的天然产物，是一种首次青霉菌中分离出的酚酸和真菌代谢产物。Fulvic Acid 抑制淀粉样蛋白b (17-42) (AB17-42)二聚化，破坏预先形成的AB17-42三聚体，并结合到磷酸二酯酶5A (PDE5A)的催化位点，可以调节机体免疫系统，影响细胞的氧化状态，改善胃肠功能。Fulvic Acid 可作为氧化剂或还原剂，具有研究糖尿病等慢性炎症性疾病的潜力。

天然产物

Cat.No: T2212

Synonym: 栀子苷,京尼平甙

Target: Beta Amyloid, Influenza Virus

Methyl tridecanoate

Cat.No: TN6919

Target: Beta Amyloid, AChE

Scyllo-Inositol

Cat.No: T8012

Synonym: Scyllitol,鲨肌醇

Target: Beta Amyloid, Endogenous Metabolite

Cat.No: T3914

Synonym: 柴胡皂苷C,柴胡皂苷 C

Target: Beta Amyloid, Caspase

Cat.No: T4S0350

Synonym: 甘草查尔酮 B,甘草查尔酮B

Target: Beta Amyloid, Others

Qingyangshengenin B

Cat.No: TMS1461

Synonym: 青阳参甙元B,青阳参苷元B,Otophylloside B

Target: Beta Amyloid

Cat.No: T0795

Synonym: Quercetin 3-O-rutinoside,芦丁,Rutoside

Target: Beta Amyloid, Prostaglandin Receptor, Autophagy

Cat.No: T22417

Synonym: 芦丁,Rutoside,Sophorin,Quercetin-3-O-rutinoside

Target: Beta Amyloid, Others, Autophagy

Cat.No: T1686

Synonym: 苏木精,Hydroxybrazilin,Natural Black 1,Haematoxylin

Target: Beta Amyloid, Others

Schisantherin B

Cat.No: T6S1918

Synonym: Gomisin-B,Wuweizi ester-B,五味子酯乙,Schizantherin-B

Target: Beta Amyloid, Others

Cat.No: T0883

Synonym: Homotaurine,3-Amino-1-propanesulfonic acid,Alzhemed,高牛黄酸

Target: Beta Amyloid, GABA Receptor

Notoginsenoside R1

Cat.No: T2961

Synonym: Sanqi glucoside R1,Sanchinoside R1,三七皂苷R1

Target: Apoptosis, ERK, Beta Amyloid

Cat.No: T2872

Synonym: 人参皂苷 Re,Ginsenoside B2,Panaxoside Re,Chikusetsusaponin Ivc,Sanchinoside Re,人参皂苷Re

Target: Beta Amyloid, NF-κB, Endogenous Metabolite, JNK

Ginsenoside Rg1

Cat.No: T2777

Synonym: Sanchinoside C1,Panaxoside Rg1,Sanchinoside Rg1,人参皂苷Rg1,Panaxoside A,人参皂苷 Rg1,Ginsenoside A2

Target: Apoptosis, Beta Amyloid, NF-κB

Ginsenoside Rg2

Cat.No: T2873

Synonym: Chikusetsusaponin I,Panaxoside Rg2,人参皂苷Rg2,Prosapogenin C2,(20S)Ginsenoside Rg2,人参皂苷 Rg2

Target: Beta Amyloid, GSK-3, NF-κB

20(S)-Ginsenoside Rg3

Cat.No: T3402

Synonym: 20(S)-人参皂苷 Rg3,人参皂苷 Rg3,20(S)-Ginsenoside-Rg3,Rg3,20S-Ginsenoside Rg3,Ginsenoside Rg3,S-Ginsenoside Rg3

Target: EGFR, Beta Amyloid, Potassium Channel, NF-κB, COX, Sodium Channel, Endogenous Metabolite

Cat.No: TN1653

Target: ERK, Beta Amyloid, AChR

Cat.No: TN1736

Synonym: 棉皮素-8-O-Β-D-葡萄糖醛酸苷,棉花皮素-8-O-葡萄糖醛酸苷

Target: Adenosine deaminase

2-O-Acetyl-20-hydroxyecdysone

Cat.No: TN1216

Synonym: 20-Hydroxyeedysone 2-acetate

Target: Beta Amyloid, Others

(-)-Epigallocatechin

Cat.No: T2987

Synonym: 表没食子儿茶素,(-)-表没食子儿茶素,l-Epigallocatechin,Epigallocatechin,EGC

Target: MMP, Autophagy

Cat.No: T3769

Target: Others, Beta-Secretase, AChE

Cat.No: TN2190

Target: Apoptosis, Beta-Secretase, BACE, Parasite

Cat.No: TN1038

Target: Apoptosis

8-Deoxygartanin

Cat.No: TN1341

Synonym: 8-脱氧藤黄苷

Target: Beta Amyloid, NF-κB, Parasite

Kaempferol-3,7-di-O-β-glucoside

Cat.No: TN4368

Synonym: Kaempferol 3,7-di-O-glucoside

Target: Glucosidase, Amylase

Bisdemethoxycurcumin

Cat.No: TL0007

Synonym: 双去甲氧基姜黄素,Curcumin III,Didemethoxycurcumin

Target: Epigenetic Reader Domain, Wnt/beta-catenin

Cat.No: TN1420

Target: Others

Cat.No: T32614

Synonym: (-)-Clausenamide

Target: Microtubule Associated

Cat.No: T2S0843

Synonym: 黄芩素-7-甲醚,7-O-Methylbaicalein,Baicalein-7-methylether

Target: IL Receptor, TNF, NOS, Interleukin

Coumarinic acid

Cat.No: T79968

Target: Others

Cat.No: T37957

Target: Others

Cat.No: TN3618

Target: Beta Amyloid, BCL, Caspase

2',3'-Dihydroxy-4',6'-dimethoxychalcone

Cat.No: T83407

Cat.No: T38108

Target: Antioxidant, PDE

Species：

Expression System：

Tag：

Cat. No.	Product Name	Species	Expression System
TMPY-03195	Serum Amyloid P Protein, Human, Recombinant (His) amyloid P component, serum,HEL-S-92n,SAP,PTX2	Human	HEK293 Cells
	Serum Amyloid P Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 24.7 kDa and the accession number is P02743.
TMPJ-00782	Amyloid Precursor Protein, Human, Recombinant (hFc) Amyloid Precursor,Amyloid Precursor Protei...	Human	HEK293 Cells
	Amyloid precursor protein (APP) is a type I membrane protein with several isoforms due to alternative splicing, performs physiological functions on the surface of neurons relevant to neurite growth, neuronal adhesion and axonogenesis. Of the three major splice isoforms of APP (APP695, APP751, and APP770) APP695 is the predominant neuronal form from which Amyloid beta peptide and transcriptionally-active cleaved intracellular domain of APP (AICD) are preferentially generated by selective process...
TMPY-00666	Serum Amyloid P Protein, Mouse, Recombinant (His) amyloid P component, serum,Sap	Mouse	HEK293 Cells
	Serum Amyloid P Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 25.3 kDa and the accession number is P12246.
TMPY-02370	Serum Amyloid P Protein, Rat, Recombinant (His) amyloid P component, serum	Rat	HEK293 Cells
	Serum Amyloid P Protein, Rat, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 25.3 kDa and the accession number is P23680.
TMPY-06808	Serum Amyloid P Protein, Human, Recombinant (hFc) PTX2,HEL-S-92n,SAP,amyloid P component, serum	Human	HEK293 Cells
	Serum Amyloid P Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 49.98 kDa and the accession number is P02743.
TMPY-02110	Beta-amyloid 40/Beta-APP40 Protein, Human, Recombinant (His & GST) AD1,ABPP,CTFγ,APPI,ABETA,β-amyloid 40/β-APP40,Aβ,CV...	Human	E. coli
	Beta-amyloid 40/Beta-APP40 Protein, Human, Recombinant (His & GST) is expressed in E. coli expression system with His and GST tag. The predicted molecular weight is 31.8 kDa and the accession number is P05067-1.
TMPY-02221	Beta-amyloid 42/Beta-APP42 Protein, Human, Recombinant (His & GST) CVAP,PN2,amyloid β (A4) precursor protein,Aβ,CTFγ,β...	Human	E. coli
	Beta-amyloid 42/Beta-APP42 Protein, Human, Recombinant (His & GST) is expressed in E. coli expression system with His and GST tag. The predicted molecular weight is 32.4 kDa and the accession number is P05067-1.
TMPY-03885	Beta-amyloid 38/Beta-APP38 Protein, Human, Recombinant (aa 672-709, His & GST) AD1,AAA,ABETA,CVAP,PN-II,CTFgamma,Aβ,APPI,PN2,CTFγ,β-amy...	Human	E. coli
	Beta-amyloid 38/Beta-APP38 Protein, Human, Recombinant (aa 672-709, His & GST) is expressed in E. coli expression system with His and GST tag. The predicted molecular weight is 32.1 kDa and the accession number is P05067-1.
TMPY-03884	Beta-amyloid 39/Beta-APP39 Protein, Human, Recombinant (aa 672-710, His & GST) CTFgamma,PN-II,AAA,Aβ,PN2,APPI,AD1,amyloid beta (A4...	Human	E. coli
	Beta-amyloid 39/Beta-APP39 Protein, Human, Recombinant (aa 672-710, His & GST) is expressed in E. coli expression system with His and GST tag. The predicted molecular weight is 32.2 kDa and the accession number is P05067-1.
TMPH-01563	IAPP Protein, Human, Recombinant (His) IAPP,Diabetes-associated peptide,Insulinoma amyloid...	Human	P. pastoris (Yeast)
	Selectively inhibits insulin-stimulated glucose utilization and glycogen deposition in muscle, while not affecting adipocyte glucose metabolism.
TMPH-01562	IAPP Protein, Human, Recombinant (GST) Insulinoma amyloid peptide,IAPP,Islet amyloid	Human	E. coli
	Selectively inhibits insulin-stimulated glucose utilization and glycogen deposition in muscle, while not affecting adipocyte glucose metabolism. IAPP Protein, Human, Recombinant (GST) is expressed in E. coli expression system with N-GST tag. The predicted molecular weight is 31.4 kDa and the accession number is P10997.
TMPY-04693	APLP1 Protein, Mouse, Recombinant (His) amyloid β (A4) precursor-like protein 1,amyloid...	Mouse	HEK293 Cells
	APLP1 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 62.4 kDa and the accession number is Q03157.
TMPJ-00523	SAA2 Protein, Human, Recombinant (His) SAA2,SAA,Serum Amyloid A2	Human	E. coli
	Serum amyloid A-2 protein (SAA2) belongs to the SAA family. It expressed by the liver and secreted in plasma. SAA2 functions as major acute phase reactant and could works as apolipoprotein of the HDL complex. Increased levels of A-SAA in serum are indicative of inflammatory disease. When highly expressed, SAA can displace ApoA1 as the major apolipoprotein in HDL complexes, weakening the function of HDL as a reverse (lipid clearing) cholesterol transporter. A highly charged region of SAA2 and SAA...
TMPH-00357	SAA1 Protein, Feline, Recombinant (His) Serum amyloid A protein,SAA1	Feline	P. pastoris (Yeast)
	Major acute phase reactant. Apolipoprotein of the HDL complex. SAA1 Protein, Feline, Recombinant (His) is expressed in yeast with N-6xHis tag. The predicted molecular weight is 12.1 kDa and the accession number is P19707.
TMPJ-00684	SNCA Protein, Mouse, Recombinant (His) Snca,Non-A β component of AD amyloid,Non-A4 compone...	Mouse	E. coli
	Alpha-synuclein (Snca) belongs to a family of proteins including a-, b-, and g-synucleins. Alpha-synuclein has been found to be implicated in the pathophysiology of many neurodegenerative diseases, including Parkinson's disease (PD) and Alzheimer's disease. Manyneurodegenerative diseases has shown that alpha-synuclein accumulates in dystrophic neurites and in Lewy bodies. The function of alpha-synuclein is closely correlated with its three-dimensional structure, especially for proteins important...
TMPY-03628	APLP1 Protein, Human, Recombinant (His) amyloid beta (A4) precursor-like protein 1,APLP,	Human	HEK293 Cells
	APLP1 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 61.9 kDa and the accession number is P51693-1.
TMPJ-00023	SNCA Protein, Human, Recombinant (His) α-Synuclein,Alpha-Synuclein,PARK1,Non-A β Component of AD	Human	E. coli
	SNCA Protein, Human, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 18 KDa and the accession number is P37840.
TMPJ-00683	SNCA Protein, Mouse, Recombinant NACP,α-synuclein,Non-A beta component of AD amyloid...	Mouse	E. coli
	SNCA Protein, Mouse, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 17 KDa and the accession number is O55042.
TMPH-00358	SAA1 Protein, Feline, Recombinant (B2M & His) Serum amyloid A protein,SAA1	Feline	E. coli
	Major acute phase reactant. Apolipoprotein of the HDL complex. SAA1 Protein, Feline, Recombinant (B2M & His) is expressed in E. coli expression system with N-6xHis-B2M tag. The predicted molecular weight is 24.1 kDa and the accession number is P19707.
TMPH-03501	SAA1 Protein, Sheep, Recombinant (His) SAA1,Serum amyloid A protein	Sheep	E. coli
	Major acute phase reactant. Apolipoprotein of the HDL complex. SAA1 Protein, Sheep, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 18.7 kDa and the accession number is P42819.
TMPH-00501	SAA1 Protein, Canine, Recombinant (GST & His) SAA1,Serum amyloid A protein	Canine	E. coli
	Major acute phase reactant. Apolipoprotein of the HDL complex. SAA1 Protein, Canine, Recombinant (GST & His) is expressed in E. coli expression system with N-6xHis-GST tag. The predicted molecular weight is 42.5 kDa and the accession number is P19708.
TMPH-00836	SAA1 Protein, Horse, Recombinant (His) Serum amyloid A protein,SAA1	Horse	E. coli
	Major acute phase reactant. Apolipoprotein of the HDL complex. SAA1 Protein, Horse, Recombinant (His) is expressed in E. coli expression system with N-10xHis tag. The predicted molecular weight is 15.8 kDa and the accession number is P19857.
TMPH-00302	SAA1 Protein, Bovine, Recombinant (His) Serum amyloid A protein,SAA1	Bovine	E. coli
	Major acute phase reactant. Apolipoprotein of the HDL complex. SAA1 Protein, Bovine, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 18.6 kDa and the accession number is P35541.
TMPH-02902	SAA3 Protein, Mouse, Recombinant (His) Serum amyloid A-3 protein,Saa3	Mouse	P. pastoris (Yeast)
	Major acute phase reactant. Apolipoprotein of the HDL complex. SAA3 Protein, Mouse, Recombinant (His) is expressed in yeast with N-6xHis tag. The predicted molecular weight is 13.8 kDa and the accession number is P04918.
TMPJ-00480	SAA1 Protein, Human, Recombinant (His) SAA1,SAA,Serum Amyloid A-1 Protein	Human	E. coli
	Serum Amyloid A1 Protein (SAA1) is an acute phase apolipoprotein reactant that is produced predominantly by hepatocytes and is under the regulation of inflammatory cytokines. SAA is produced mainly in the liver and circulates in low levels in the blood. SAA may play a role in the immune system and facilitate the repair of injured tissues, it also acts as an antibacterial agent, and signals the migration of germ-fighting cells to sites of infection. SAA also functions as an apolipoprotein of the ...
TMPY-02947	SAA4 Protein, Human, Recombinant (GST) SAA4,serum amyloid A4, constitutive,C-SAA,CSAA	Human	E. coli
	SAA4 is a member of the SAA family. SAA proteins are family of apolipoproteins of high density lipoprotein (HDL). They can be separated into two distinct groups. First group (SAA1, SAA2, and SAA3) consists of acute phase reactant whose expression level increase in the blood in a response to trauma, infection, inflammation, and neoplasia. These acute phase SAAs associates with HDL during inflammation and remodel the HDL particle by displacing Apo-A1. The second distinct group consists of SAA4 and...
TMPH-02900	SAA1 Protein, Mouse, Recombinant (His) Serum amyloid A-1 protein,Saa1	Mouse	E. coli
	Major acute phase protein. SAA1 Protein, Mouse, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 17 kDa and the accession number is P05366.
TMPH-02901	SAA3 Protein, Mouse, Recombinant (E. coli, His) Serum amyloid A-3 protein,Saa3	Mouse	E. coli
	Major acute phase reactant. Apolipoprotein of the HDL complex. SAA3 Protein, Mouse, Recombinant (E. coli, His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 15.8 kDa and the accession number is P04918.
TMPY-06460	Alpha-Synuclein Protein, Mouse, Recombinant (His) alphaSYN,synuclein, α (non A4 component of amyloid ...	Mouse	E. coli
	Alpha-Synuclein Protein, Mouse, Recombinant (His) is expressed in E. coli expression system with His tag. The predicted molecular weight is 15.31 kDa and the accession number is O55042-1.
TMPY-00668	APP/Protease nexin-II Protein, Human, Recombinant (hFc) CTFγ,amyloid beta (A4) precursor protein,AAA,ABPP,C...	Human	HEK293 Cells
	APP/Protease nexin-II Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 101 kDa and the accession number is P05067-8.
TMPY-02512	Alpha-Synuclein Protein, Human, Recombinant PD1,α-Synuclein,PARK4,synuclein, α (non A4 component of ...	Human	E. coli
	Alpha-Synuclein Protein, Human, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 14.5 kDa and the accession number is P37840-1.
TMPY-06318	Alpha-Synuclein Protein,Human,Recombinant (H50Q) Human α-Synuclein Protein (H50Q),synuclein, alpha (non A4 co...	Human	E. coli
	Alpha-Synuclein Protein,Human,Recombinant (H50Q) is expressed in E. coli expression system. The predicted molecular weight is 14.45 kDa and the accession number is P37840-1.
TMPJ-00338	LRRC15 Protein, Human, Recombinant (His & Avi), Biotinylated Leucine-rich repeat-containing protein 15,LIB,LRRC15,Leucine...	Human	HEK293 Cells
	The type I transmembrane protein 15-leucine-rich repeat containing membrane protein (LRRC15) is a member of the LRR superfamily. The LRR family is a structural module for protein-protein and protein-matrix interactions used for molecular recognition process such as cell adhesion, signal transduction, DNA repair, and RNA processing. The LRRC15 is also a transmembrane protein demonstrated to play important roles in cancer. LRRC15 expression was notably increased 4.6-fold in cariesdiseased pulpal t...
TMPH-01863	PIEZO1 Protein, Human, Recombinant (His & Myc) Protein FAM38A,Membrane protein induced by beta-amyloid<...	Human	E. coli
	PIEZO1 Protein, Human, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 33.6 kDa and the accession number is Q92508.
TMPJ-00722	APBA3 Protein, Human, Recombinant (His) Neuronal Munc18-1-Interacting Protein 3,Neuron-Specific X11L...	Human	E. coli
	Amyloid β A4 Precursor Protein-Binding Family A Member 3 (APBA3) is an adapter protein that belongs to the X11 family. APBA3 contains 2 PDZ (DHR) domains and 1 PID domain and interacts with the Alzheimer's disease amyloid precursor protein.. APBA3 is believed to be involved in signal transduction processes. Unlike X11-α and -β which are generally neuronal proteins, APBA3 is widely expressed in all tissues examined with lower levels in brain and testis. It binds to the cytoplasmic domain of amylo...
TMPH-00928	APBA2 Protein, Human, Recombinant (E. coli, His & Myc) Neuronal Munc18-1-interacting protein 2 (Mint-2),Amyloid...	Human	E. coli
	APBA2 Protein, Human, Recombinant (E. coli, His & Myc) is expressed in E. coli.
TMPH-00929	APBA2 Protein, Human, Recombinant (His & Myc) Adapter protein X11beta,MINT2,Neuronal Munc18-1-interacting ...	Human	HEK293 Cells
	Putative function in synaptic vesicle exocytosis by binding to STXBP1, an essential component of the synaptic vesicle exocytotic machinery. May modulate processing of the amyloid-beta precursor protein (APP) and hence formation of APP-beta. APBA2 Protein, Human, Recombinant (His & Myc) is expressed in HEK293 mammalian cells with N-10xHis and C-Myc tag. The predicted molecular weight is 87.5 kDa and the accession number is Q99767.
TMPY-04396	C-ABL/ABL1 Protein, Human, Recombinant (GST) v-abl,ABL,JTK7,ABL proto-oncogene 1, non-receptor tyrosine k...	Human	Baculovirus Insect Cells
	c-Abl belongs to the class of tyrosine kinases and is the prototype of a subfamily which includes two members, c-Abl and Arg (Abl-related gene). Both proteins are localized at the cell membrane, actin cytoskeleton and cytosol, and c-Abl is present in the nucleus as well. c-Abl is a non-receptor tyrosine kinase that participates in multiple signaling pathways linking the cell surface, cytoskeleton, and the nucleus. Recent in vitro studies have also linked c-Abl to amyloid-beta-induced toxicity an...
TMPY-01101	Coagulation factor X/F10 Protein, Human, Recombinant (His) FXA,FX,coagulation factor X,coagulation factor 10	Human	Baculovirus Insect Cells
	Coagulation factor X, also known as FX, F10, Eponym Stuart-Prower factor, and thrombokinase, is an enzyme of the coagulation cascade. It is one of the vitamin K-dependent serine proteases, and plays a crucial role in the coagulation cascade and blood clotting, as the first enzyme in the common pathway of thrombus formation. Factor X deficiency is one of the rarest of the inherited coagulation disorders. FX deficiency among the most severe of the rare coagulation defects, typically including hema...
TMPJ-01398	ITM2B Protein, Human, Recombinant (His) Transmembrane Protein BRI,Protein E25B,BRI2,imBRI2,Immature ...	Human	HEK293 Cells
	Integral Membrane Protein 2B (ITM2B) is expressed in the Golgi and on the cell surface. ITM2B forms homodimer through disulfide-linked interaction with SPPL2A, SPPL2B and APP. ITM2B is expressed in brain and the other tissues. Defects in ITM2B cause cerebral amyloid angiopathy ITM2B-related type 1(CAA-ITM2B1) and amyloid angiopathy ITM2B-related type 2(CAA-ITM2B2). CAA-ITM2B1 is characterized by amyloid deposition in the walls of cerebral blood vessels and neurodegeneration in the central nervou...
TMPH-02778	Mcpt4 Protein, Mouse, Recombinant (E. coli, His) MSMCP,Mast cell protease 4,Myonase,Serosal mast cell proteas...	Mouse	E. coli
	Has chymotrypsin-like activity. Hydrolyzes the amide bonds of synthetic substrates having Tyr and Phe residues at the P1 position. Preferentially hydrolyzes the 'Tyr-4-\|-Ile-5' bond of angiotensin I and the 'Phe-20-\|-Ala-21' bond of amyloid beta-protein, and is less active towards the 'Phe-8-\|-His-9' bond of angiotensin I and the 'Phe-4-\|-Ala-5' and 'Tyr-10-\|-Glu-11' bonds of amyloid beta-protein. Involved in thrombin regulation and fibronectin processing. Mcpt4 Protein, Mouse, Recombinant (E. c...
TMPK-00507	TREM2 Protein, Cynomolgus, Recombinant (His) TREM2,Trem2a,PLOSL2,TREM-2,Trem2c,Trem2b	Cynomolgus	HEK293 Cells
	TREM-2 (Triggering Receptor Expressed on Myeloid cells-2) is a 35 kDa type I transmembrane member of the TREM family and Ig superfamily. Mature human TREM-2 consists of a 156 amino acid (aa) extracellular domain (ECD) with one V-type Ig-like domain, a 21 aa transmembrane (TM) domain, and a 35 aa cytoplasmic tail. TREM-2 forms a receptor signaling complex with TYROBP which mediates signaling and cell activation following ligand binding (PubMed:10799849). Acts as a receptor for amyloid-beta prote...
TMPJ-00851	IDE Protein, Human, Recombinant (His) Insulysin,Insulinase,Insulin-Degrading Enzyme,IDE,Abeta-Degr...	Human	HEK293 Cells
	Insulin-Degrading Enzyme (IDE) is a secreted enzyme that belongs to the peptidase M16 family. IDE is a large zinc-binding protease and cleaves multiple short polypeptides that vary considerably in sequence. IDE plays a role in the cellular breakdown of insulin, IAPP, glucagon, bradykinin, kallidin, and other peptides, and thereby plays a role in intercellular peptide signaling. IDE degrades amyloid formed by APP and IAPP. IDE may participate in the degradation and clearance of naturally secreted...
TMPK-00935	APLP2 Protein, Human, Recombinant (His) APPL2,YWK-II,APPH,CDEI box-binding,CDEBP	Human	HEK293 Cells
	Amyloid β precursor-like protein 2 (APLP2) has been determined to serve an important role in the progression of a number of cancer types. APLP2 expression was significantly associated with disease-specific survival (P<0.001). APLP2 may be used to potentially predict patient prognosis, and to guide clinical diagnosis and treatment in CCRCC.
TMPK-01146	LGMN Protein, Human, Recombinant (His) AI746452,Legumain,LGMN1,Prsc1,AEP,LGMN,AU022324	Human	HEK293 Cells
	Recently, functional studies have demonstrated that legumain (LGMN) cleaves both amyloid β-protein precursor and tau, promoting senile plaques and formation of neurofibrillary tangles, which may play a crucial role in the pathogenesis of Alzheimer's disease (AD). In single-variant association analysis, none of the common variants in LGMN were statistically significant. In gene-based analysis, the LGMN gene also showed no association with AD.
TMPY-01303	Serpin A3 Protein, Human, Recombinant (His) ACT,GIG25,serpin peptidase inhibitor, clade A (alpha-1 antip...	Human	HEK293 Cells
	SerpinA3, also known as Alpha 1-antichymotrypsin (AACT), is a plasma alpha globulin glycoprotein, and is a member of serpin superfamily of the serine protease inhibitors consisting of at least 35 members. SerpinA3 has been demonstrated to inhibit the activity of certain serine proteases, such as cathepsin G found in neutrophils, and chymases present in mast cells, by inducing a major conformational rearrangement, and thus protects some tissues from damage caused by proteolytic enzymes. This enzy...
TMPH-03328	Mcpt1 Protein, Rat, Recombinant (Myc) Mast cell protease I,Mcpt1,Chymase,Mast cell protease 1,Chym...	Rat	E. coli
	Major secreted protease of mast cells with suspected roles in vasoactive peptide generation, extracellular matrix degradation, and regulation of gland secretion. May participate in generating perivascular beta-protein which ultimately aggregates into amyloid-beta deposits. Mcpt1 Protein, Rat, Recombinant (Myc) is expressed in E. coli expression system with N-Myc tag. The predicted molecular weight is 28.6 kDa and the accession number is P09650.
TMPH-02106	SH3PXD2A Protein, Human, Recombinant (His & Myc) SH3PXD2A,SH3 multiple domains protein 1,SH3 and PX domain-co...	Human	E. coli
	Adapter protein involved in invadopodia and podosome formation, extracellular matrix degradation and invasiveness of some cancer cells. Binds matrix metalloproteinases (ADAMs), NADPH oxidases (NOXs) and phosphoinositides. Acts as an organizer protein that allows NOX1- or NOX3-dependent reactive oxygen species (ROS) generation and ROS localization. In association with ADAM12, mediates the neurotoxic effect of amyloid-beta peptide.
TMPK-01065	SEZ6 Protein, Mouse, Recombinant (His) BSRP-C,SEZ-6,BSRPC,SEZ6	Mouse	HEK293 Cells
	Seizure-related protein 6 (Sez6) contributes to chronic pain development as sez6 knockout mice show attenuated pain behaviours after peripheral nerve injury, compared with control mice. The type I transmembrane isoform of Sez6 is cleaved by the β-amyloid precursor protein cleavage enzyme 1 (BACE1), resulting in Sez6 extracellular domain shedding from the neuron surface. SEZ6 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with C-His tag. The predicted molecular weight is...
TMPK-00997	SEZ6 Protein, Human, Recombinant (hFc) SEZ-6,BSRP-C,SEZ6,BSRPC	Human	HEK293 Cells
	Seizure-related protein 6 (Sez6) contributes to chronic pain development as sez6 knockout mice show attenuated pain behaviours after peripheral nerve injury, compared with control mice. The type I transmembrane isoform of Sez6 is cleaved by the β-amyloid precursor protein cleavage enzyme 1 (BACE1), resulting in Sez6 extracellular domain shedding from the neuron surface. SEZ6 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with C-hFc tag. The predicted molecular weight is...
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重组蛋白

Serum Amyloid P Protein, Human, Recombinant (His)

Cat.No: TMPY-03195

Species: Human

Expression System: HEK293 Cells

Amyloid Precursor Protein, Human, Recombinant (hFc)

Cat.No: TMPJ-00782

Species: Human

Expression System: HEK293 Cells

Serum Amyloid P Protein, Mouse, Recombinant (His)

Cat.No: TMPY-00666

Species: Mouse

Expression System: HEK293 Cells

Serum Amyloid P Protein, Rat, Recombinant (His)

Cat.No: TMPY-02370

Species: Rat

Expression System: HEK293 Cells

Serum Amyloid P Protein, Human, Recombinant (hFc)

Cat.No: TMPY-06808

Species: Human

Expression System: HEK293 Cells

Beta-amyloid 40/Beta-APP40 Protein, Human, Recombinant (His & GST)

Cat.No: TMPY-02110

Species: Human

Expression System: E. coli

Beta-amyloid 42/Beta-APP42 Protein, Human, Recombinant (His & GST)

Cat.No: TMPY-02221

Species: Human

Expression System: E. coli

Beta-amyloid 38/Beta-APP38 Protein, Human, Recombinant (aa 672-709, His & GST)

Cat.No: TMPY-03885

Species: Human

Expression System: E. coli

Beta-amyloid 39/Beta-APP39 Protein, Human, Recombinant (aa 672-710, His & GST)

Cat.No: TMPY-03884

Species: Human

Expression System: E. coli

IAPP Protein, Human, Recombinant (His)

Cat.No: TMPH-01563

Species: Human

Expression System: P. pastoris (Yeast)

IAPP Protein, Human, Recombinant (GST)

Cat.No: TMPH-01562

Species: Human

Expression System: E. coli

APLP1 Protein, Mouse, Recombinant (His)

Cat.No: TMPY-04693

Species: Mouse

Expression System: HEK293 Cells

SAA2 Protein, Human, Recombinant (His)

Cat.No: TMPJ-00523

Species: Human

Expression System: E. coli

SAA1 Protein, Feline, Recombinant (His)

Cat.No: TMPH-00357

Species: Feline

Expression System: P. pastoris (Yeast)

SNCA Protein, Mouse, Recombinant (His)

Cat.No: TMPJ-00684

Species: Mouse

Expression System: E. coli

APLP1 Protein, Human, Recombinant (His)

Cat.No: TMPY-03628

Species: Human

Expression System: HEK293 Cells

SNCA Protein, Human, Recombinant (His)

Cat.No: TMPJ-00023

Species: Human

Expression System: E. coli

SNCA Protein, Mouse, Recombinant

Cat.No: TMPJ-00683

Species: Mouse

Expression System: E. coli

SAA1 Protein, Feline, Recombinant (B2M & His)

Cat.No: TMPH-00358

Species: Feline

Expression System: E. coli

SAA1 Protein, Sheep, Recombinant (His)

Cat.No: TMPH-03501

Species: Sheep

Expression System: E. coli

SAA1 Protein, Canine, Recombinant (GST & His)

Cat.No: TMPH-00501

Species: Canine

Expression System: E. coli

SAA1 Protein, Horse, Recombinant (His)

Cat.No: TMPH-00836

Species: Horse

Expression System: E. coli

SAA1 Protein, Bovine, Recombinant (His)

Cat.No: TMPH-00302

Species: Bovine

Expression System: E. coli

SAA3 Protein, Mouse, Recombinant (His)

Cat.No: TMPH-02902

Species: Mouse

Expression System: P. pastoris (Yeast)

SAA1 Protein, Human, Recombinant (His)

Cat.No: TMPJ-00480

Species: Human

Expression System: E. coli

SAA4 Protein, Human, Recombinant (GST)

Cat.No: TMPY-02947

Species: Human

Expression System: E. coli

SAA1 Protein, Mouse, Recombinant (His)

Cat.No: TMPH-02900

Species: Mouse

Expression System: E. coli

SAA3 Protein, Mouse, Recombinant (E. coli, His)

Cat.No: TMPH-02901

Species: Mouse

Expression System: E. coli

Alpha-Synuclein Protein, Mouse, Recombinant (His)

Cat.No: TMPY-06460

Species: Mouse

Expression System: E. coli

APP/Protease nexin-II Protein, Human, Recombinant (hFc)

Cat.No: TMPY-00668

Species: Human

Expression System: HEK293 Cells

Alpha-Synuclein Protein, Human, Recombinant

Cat.No: TMPY-02512

Species: Human

Expression System: E. coli

Alpha-Synuclein Protein,Human,Recombinant (H50Q)

Cat.No: TMPY-06318

Species: Human

Expression System: E. coli

LRRC15 Protein, Human, Recombinant (His & Avi), Biotinylated

Cat.No: TMPJ-00338

Species: Human

Expression System: HEK293 Cells

PIEZO1 Protein, Human, Recombinant (His & Myc)

Cat.No: TMPH-01863

Species: Human

Expression System: E. coli

APBA3 Protein, Human, Recombinant (His)

Cat.No: TMPJ-00722

Species: Human

Expression System: E. coli

APBA2 Protein, Human, Recombinant (E. coli, His & Myc)

Cat.No: TMPH-00928

Species: Human

Expression System: E. coli

APBA2 Protein, Human, Recombinant (His & Myc)

Cat.No: TMPH-00929

Species: Human

Expression System: HEK293 Cells

C-ABL/ABL1 Protein, Human, Recombinant (GST)

Cat.No: TMPY-04396

Species: Human

Expression System: Baculovirus Insect Cells

Coagulation factor X/F10 Protein, Human, Recombinant (His)

Cat.No: TMPY-01101

Species: Human

Expression System: Baculovirus Insect Cells

ITM2B Protein, Human, Recombinant (His)

Cat.No: TMPJ-01398

Species: Human

Expression System: HEK293 Cells

Mcpt4 Protein, Mouse, Recombinant (E. coli, His)

Cat.No: TMPH-02778

Species: Mouse

Expression System: E. coli

TREM2 Protein, Cynomolgus, Recombinant (His)

Cat.No: TMPK-00507

Species: Cynomolgus

Expression System: HEK293 Cells

IDE Protein, Human, Recombinant (His)

Cat.No: TMPJ-00851

Species: Human

Expression System: HEK293 Cells

APLP2 Protein, Human, Recombinant (His)

Cat.No: TMPK-00935

Species: Human

Expression System: HEK293 Cells

LGMN Protein, Human, Recombinant (His)

Cat.No: TMPK-01146

Species: Human

Expression System: HEK293 Cells

Serpin A3 Protein, Human, Recombinant (His)

Cat.No: TMPY-01303

Species: Human

Expression System: HEK293 Cells

Mcpt1 Protein, Rat, Recombinant (Myc)

Cat.No: TMPH-03328

Species: Rat

Expression System: E. coli

SH3PXD2A Protein, Human, Recombinant (His & Myc)

Cat.No: TMPH-02106

Species: Human

Expression System: E. coli

SEZ6 Protein, Mouse, Recombinant (His)

Cat.No: TMPK-01065

Species: Mouse

Expression System: HEK293 Cells

SEZ6 Protein, Human, Recombinant (hFc)

Cat.No: TMPK-00997

Species: Human

Expression System: HEK293 Cells

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Cat. No.	Product Name	Target	Signaling Pathways
TMID-0170	Homotaurine-d6
	Homotaurine-d6 是 Homotaurine 的氘代化合物。Homotaurine 的 CAS 号为 3687-18-1。Homotaurine 是一种具有口服活性的、可透过血脑屏障的天然氨基酸，存在于各种红色海藻中，能够可溶性 Aβ 结合并以非原纤维形式维持 Aβ。它是一种 GABA 类似物，具有神经保护，抗惊厥和抗高血压的活性。
TMIH-0549	Tafamidis-d3
	Tafamidis-d3 是 Tafamidis 的氘代化合物。Tafamidis 的 CAS 号为 594839-88-0。Tafamidis 是选择性的transthyretin (TTR)稳定剂，对野生型 WT-TTR 、突变型同源四聚体 V30M-TTR、V122I-TTR 的活性相当，它们的EC50值为2.7-3.2 μM。它对淀粉样蛋白的生成具有抑制作用。
T36903	Rasagiline-13C3 (mesylate) Rasagiline-13C3 (mesylate)
	Rasagiline-13C3is intended for use as an internal standard for the quantification of rasagiline by GC- or LC-MS. Rasagiline is an inhibitor of monoamine oxidase B (MAO-B; IC50= 4.43 nM for the rat brain enzyme).1It is selective for MAO-B over MAO-A (IC50= 412 nM for the rat brain enzyme). It inhibits serum and NGF withdrawal-induced apoptosis of PC12 cells when used at concentrations ranging from 0.01 to 100 μM.2Rasagiline inhibits rat brain MAO-Bin vivo(ED50= 0.1 mg/kg).1It reduces cerebral ede...

同位素标记化合物

Cat.No: TMID-0170

Cat.No: TMIH-0549

Rasagiline-13C3 (mesylate)

Cat.No: T36903

Synonym: Rasagiline-13C3 (mesylate)

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