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Search Results for " adenosine "
Targets Recommended: Adenosine Receptor Adenosine deaminase Nucleoside Antimetabolite/Analog

694

抑制剂 & 化合物

77

天然产物

3

化合物库

14

重组蛋白

7

同位素标记化合物

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Cat. No. Product Name
L1120 AMPK靶向分子库

80 compounds
80 个靶向AMPK 的分子集合,可用于高通量和高内涵筛选;
L7700 神经再生化合物库

524 compounds
524 种神经再生相关化合物的独特集合,可用于高通量筛选和高内涵筛选;
L5300 线粒体靶向库

812 compounds
812 种具有潜在或确定线粒体靶向活性的化合物,以促进针对线粒体的药物研究;

化合物库

AMPK靶向分子库
Cat.No: L1120
Compounds: 80
神经再生化合物库
Cat.No: L7700
Compounds: 524
线粒体靶向库
Cat.No: L5300
Compounds: 812
Cat. No. Product Name Target Signaling Pathways
T32826 LNA-Adenosine

LNA-A,LNA Adenosine,2'-O,4'-C-Methyleneadenosine

Nucleoside Antimetabolite/Analog Cell Cycle/Checkpoint; DNA Damage/DNA Repair
LNA-Adenosine (LNA-A) 是一种核苷类似物,可作为作为腺苷A3受体配体。
T23636 Adenosine N1-oxide

ANO,1-Oxoadenosine,Adenosine N1 oxide,Adenosine, 1-oxide,腺苷氮氧化物

Immunology/Inflammation related Immunology/Inflammation
Adenosine N1-oxide (1-Oxoadenosine) 是在蜂王浆中发现的腺苷 N1-氧化物,可抑制活化的巨噬细胞分泌炎症介质,并降低脂多糖 (LPS) 诱导的内毒素休克的致死率。
T22231 Adenosine Dialdehyde (ADOX)

腺苷二醛,Periodate-oxidized adenosine,Adenosine, periodate oxidized,Adenox,Adenosinedialdehyde

Others Others
Adenosine Dialdehyde (Periodate-oxidized adenosine) 是嘌呤核苷类似物,是S-腺苷高半胱氨酸水解酶(SAHH)的有效抑制剂(Ki=3.3nM)。Adenosine Dialdehyde 在体内具有较强的抗肿瘤活性。
T65979 Adenosine 5'-monophosphate disodium salt

Adenosine Phosphate Disodium,5‘-AMP-NA2

Nucleoside Antimetabolite/Analog Cell Cycle/Checkpoint; DNA Damage/DNA Repair
Adenosine 5'-monophosphate disodium salt (Adenosine Phosphate Disodium) 是一种参与 ATP 代谢的嘌呤核苷酸,用于研究 ATP 对细胞和生物体的影响。Adenosine 5'-monophosphate disodium salt 已被证明具有多种生化和生理作用,它可以促进细胞代谢、基因表达和蛋白质合成。
T10247 Adenosine 5'-diphosphoribose sodium

Adenosine 5'-diphosphoribose sodium,ADP ribose sodium

Endogenous Metabolite; TRP/TRPV Channel; Autophagy Autophagy; Membrane transporter/Ion channel; Metabolism
Adenosine 5'-diphosphoribose sodium (ADP ribose sodium) 是一种烟酰胺腺嘌呤核苷酸 (NAD+) 的代谢产物,广泛存在于生物体内。Adenosine 5'-diphosphoribose sodium (ADP ribose sodium) 是一种高效的细胞内 Ca2+ 渗透性阳离子 TRPM2 通道激活剂,还可以诱导自噬 (autophagy)。
T7683 Adenosine amine congener

ADAC

Adenosine Receptor GPCR/G Protein; Neuroscience
Adenosine amine congener (ADAC) 是一种选择性的 A1 腺苷受体激动剂,具有神经保护作用,可以改善噪音和顺铂引起的耳蜗损伤。
T10248 Adenosine antagonist-1

Adenosine Receptor GPCR/G Protein; Neuroscience
Adenosine antagonist-1 可作为一种腺苷 A3 受体 (AA3R) 拮抗剂。
T12163 N6-(2-Phenylethyl)adenosine

N6-Phenethyladenosine,N6-Phenylethyladenosine

Adenosine Receptor GPCR/G Protein; Neuroscience
N6-(2-Phenylethyl)adenosine (N6-Phenethyladenosine) 是一种腺苷衍生物和腺苷受体激动剂,对大鼠和人 A1 的 Ki 值分别为 11.8 nM 和 30.1 nM。
T60103 N6-(p-Hydroxyphenethyl)-Adenosine)

Others Others
N6-(p-Hydroxyphenethyl)-Adenosine) 是一种腺苷类似物。
T14127 Adenosine A1 receptor activator T62

Adenosine Receptor GPCR/G Protein; Neuroscience
Adenosine A1 receptor activator T62 是腺苷 A1 受体的变构增强剂,有镇痛作用。
T16166 N-[(4-Aminophenyl)methyl]adenosine

Adenosine Receptor GPCR/G Protein; Neuroscience
N-[(4-Aminophenyl)methyl]adenosine是高效的腺苷受体抑制剂,可用于研究免疫系统疾病和神经系统疾病。
T22466 Adenosine receptor A1 antagonist 5

cAMP GPCR/G Protein
Adenosine receptor A1 antagonist 5 可作为一种腺苷拮抗剂,是一种氧嘌呤,可作为杀虫剂和虫害防治剂,对血压升高有抑制作用。
T21620 Adenosine receptor antagonist 4

Adenosine Receptor GPCR/G Protein; Neuroscience
Adenosine receptor antagonist 4 是一种腺苷受体拮抗剂。
T60020 5'-Fluoro-5'-deoxyadenosine

5'-Fluoro-5'-deoxy-adenosine

Others Others
5'-Fluoro-5'-deoxyadenosine (5'-Fluoro-5'-deoxy-adenosine) 常用作研究放线菌卡特链霉菌的工具。
T29347 2-Ethynyl Adenosine

2-Ethynyl-Ade,2 Ethynyl Adenosine,2-Ethynyl-Adenosine

Others Others
2-Ethynyl Adenosine is an Adenosine derivative that is used to capture novel polyadenylated transcription and non-radiochemical reporter molecules of the protein AMPylation.
T16325 NITD008

7-Deaza-2'-C-acetylene-adenosine

Others Others
NITD008 (7-Deaza-2'-C-acetylene-adenosine) 是一种有效的和选择性的腺苷核苷抑制剂,是一种腺苷核苷类似物,具有广谱的抗病毒活性,抑制登革热病毒、动物杯状病毒和寨卡病毒。
T12008 MethADP

Adenosine 5'-(α,β-methylene)diphosphate

CD73 Immunology/Inflammation
MethADP (Adenosine 5'-(α,β-methylene)diphosphate) 是一种特异性的 CD73 抑制剂,抑制 ecto-5′-核苷酸酶 (ecto),可用于研究神经系统疾病和心血管疾病。
T39011 N6-Benzyl-5'-ethylcarboxamido adenosine

N6-Benzyl-5'-ethylcarboxamido adenosine

Others Others
N6-Benzyl-5'-ethylcarboxamido adenosine is a selective A3 adenosine receptor agonist.
T38449 Guanosine 5'-triphosphate-5'-adenosine

GpppA,Guanosine 5'-triphosphate-5'-adenosine

Others Others
Guanosine 5'-triphosphate-5'-adenosine, the 5′ cap analog, is a fluorescent substrate analog.
T10212 A2AR-agonist-1

N-(2-(1H-Indol-3-yl)ethyl)adenosine

Others; Adenosine Receptor GPCR/G Protein; Neuroscience; Others
A2AR-agonist-1 (N-(2-(1H-Indol-3-yl)ethyl)adenosine)是一种有效的 A2AR 和 ENT1激动剂, Ki 值 分别为 4.39 μM 和 3.47 μM。
T40721 N7-Methyl-guanosine-5'-triphosphate-5'-adenosine

N7-Methyl-guanosine-5'-triphosphate-5'-adenosine,m7GpppA

Others Others
N7-Methylguanosine-5'-triphosphate-5'-adenosine (m7GpppA) is a dinucleotide cap analog employed in the process of in vitro RNA transcription.
TNU0431 N6-(m-Methoxybenzyl)adenosine

Endogenous Metabolite Metabolism
N6-(m-Methoxybenzyl)adenosine 是一种腺嘌呤核苷类似物,也是一种细胞分裂素衍生物,可在农业中研究枝条的生长繁殖。
T35573 Adenosine 5’-methylenediphosphate (hydrate)

Others Others
Adenosine 5’-methylenediphosphate is an inhibitor of ecto-5’-nucleotidase, also known as CD73, with a Kivalue of 37 nM.1It inhibits cAMP accumulation induced by adenosine 5’-monophosphate , adenosine 5’-diphosphate , or adenosine 5’-triphosphate but not adenosine in VA-13 human fibroblasts when used at a concentration of 100 μM. Adenosine 5’-methylenediphosphate reduces proliferation of U138MG glioma cells, as well as inhibits the invasion and migration of MHCC97H hepatocellular carcinoma (HCC) ...
T19179 Adenosine deaminase

Others Others
Adenosine deaminase is an enzyme that catalyzes the irreversible deamination of 2'-deoxyadenosine and adenosine to 2'-deoxyinosine and inosine, respectively.
T83827 Adenosine-5'-O-(3-thiotriphosphate) sodium

ATPγS,Adenosine 5'-(γ-thio)-triphosphate

Others Others
Adenosine-5'-O-(3-thiotriphosphate)(ATPγS)是一种purinergic P2Y11受体的激动剂。在表达人类或犬类P2Y11受体的CHO-K1细胞中,能够诱导肌醇磷酸累积(EC50s分别为1.2和19.3 µM)。ATPγS(10 µM)能抑制Junin病毒导致的编码骨形态生成蛋白6(BMP6)的mRNA水平增加,并减少Junin病毒感染的初代大鼠成骨细胞中的粒子形成单位(PFUs)。使用25 µM浓度时,可以诱导MIN6胰岛β细胞分泌胰岛素。
TNU0429 N6-(2-Hydroxyethyl)adenosine

Calcium Channel Membrane transporter/Ion channel; Metabolism
N6-(2-Hydroxyethyl)adenosine 是一种 Ca2+拮抗剂和抗炎剂,与脑和冠状动脉循环的控制有关,被认为具有镇静活性。
TNU0430 N6-(p-Methoxybenzyl)adenosine

Nucleoside Antimetabolite/Analog Cell Cycle/Checkpoint; DNA Damage/DNA Repair
N6-(p-Methoxybenzyl)adenosine 是一种腺嘌呤核苷类似物,在 U87MG 神经胶质瘤细胞中显示出体外抗增殖活性,在来自受刺激外周血单核细胞 (PBMC) 的离体 γδ T 细胞中表现出免疫原性。
TNU0178 2'-O-(2-Azidoethyl)adenosine

Nucleoside Antimetabolite/Analog Cell Cycle/Checkpoint; DNA Damage/DNA Repair
2'-O-(2-Azidoethyl)adenosine 是一种嘌呤核苷类似物,具有潜在的抗肿瘤活性。2’-O-(2-Azidoethyl)adenosine 的活性与抑制DNA合成和凋亡有关。
T40307 Adenosine receptor antagonist 1

Others Others
Adenosine receptor antagonist 1 is a highly selective antagonist for the A2aR adenosine receptor, exhibiting an IC50 value of 0.29 nM. It demonstrates a remarkable 14-fold selectivity towards the A2aR receptor in comparison to the A2bR receptor.
T35574 Adenosine 5'-phosphosulfate (sodium salt)

Others Others
Adenosine 5'-phosphosulfate is an ATP and sulfate competitive inhibitor of ATP sulfurylase in humans, S. cerevisiae, and P. chrysogenum (Ki = 18, 2500, and 1500 nM, respectively). Adenosine 5'-phosphosulfate also inhibits human adenosine 5'-phosphosulfate kinase (Ki = 47.5 μM) to prevent sulfation.
T38416 Adenosine 5'-succinate

Others Others
Adenosine 5'-succinate is a compound closely related to adenosine monophosphate (AMP) that demonstrates strong inhibitory properties against taste receptor activation of transducin caused by Denatonium benzoate.
T35571 Adenosine 3’-monophosphate (sodium salt hydrate)

Others Others
Adenosine 3’-monophosphate is a nucleotide and metabolite formedviahydrolysis of 2’,3’-cAMP by metal-dependent phosphodiesterases.1It reduces proliferation of rat preglomerular vascular smooth muscles cells (PGVSMCs) and glomerular mesangial cells (GMCs) in a concentration-dependent manner, an effect that is abolished by the adenosine A2Breceptor antagonist MRS1754.2Adenosine 3’-monophosphate is also a metabolic intermediate in the biosynthesis of adenosine .
T71927 Adenosine-5'-diphosphate disodium salt

Others Others
Adenosine 5'-diphosphate disodium salt has been shown to inhibit the binding of serotonin (5-hydroxytryptamine) to 5-HT2 receptors, which are present in heart tissue.
T22554 Adenosine Kinase Inhibitor (hydrate)

Others Others
Adenosine kinase is the key metabolizing enzyme regulating cellular adenosine concentrations. Inhibition of adenosine kinase can selectively enhance the protective actions of adenosine during tissue trauma without producing the nonspecific effects associa
T84880 ABT-702 hydrochloride

Adenosine Kinase Inhibitor hydrochloride

Others Others
ABT-702 hydrochloride,一种有效的腺苷激酶 (AK) 抑制剂,其IC50值为1.7 nM。
T35572 Adenosine 3',5'-diphosphate sodium salt

3'-Phosphoadenosine 5'-phosphate

Endogenous Metabolite Metabolism
Adenosine 3',5'-diphosphate sodium salt 是一种羟类固醇磺基转移酶 (hydroxysteroid sulfotransferases) 抑制剂,是一种腺嘌呤核苷酸,在戊糖核糖的 3'和 5'位置含有一个磷酸基团。Adenosine 3',5'-diphosphate (sodium salt)是 3'-phosphoadenosine 5'-phosphosulfonate (PAPS) 的产物,是磺基转移酶(SULTs)的辅助因子,已被用于研究 SULTs 的动力学特性和结构。
T12159 APNEA

(2R,3R,4S,5R)-2-[6-[2-(4-aminophenyl)ethylamino]purin-9-yl]-5-(hydroxymethyl)oxolane-3,4-diol,N6-[2-(4-Aminophenyl)ethyl]adenosine,N6-[2-(4-氨基苯基)乙基]腺嘌呤

Adenosine Receptor GPCR/G Protein; Neuroscience
APNEA ((2R,3R,4S,5R)-2-[6-[2-(4-aminophenyl)ethylamino]purin-9-yl]-5-(hydroxymethyl)oxolane-3,4-diol) 是腺苷 A3 受体的非选择性激动剂。
T37146 5'-O-DMT-2'-O-TBDMS-N-Bz-Adenosine

Others Others
5'-O-DMT-2'-O-TBDMS-N-Bz-Adenosine, an adenosine derivative, serves as an intermediate in the synthesis of oligonucleotides.
TNU1637 alpha-Adenosine

Others Others
alpha-Adenosine 是一种有用的有机化合物,可用于生命科学领域的相关研究。其产品编号为 TNU1637,CAS号为 5682-25-7。
T65008 L-Adenosine

Others Others
L-Adenosine 是一种有用的有机化合物,可用于生命科学领域的相关研究。其产品编号为 T65008,CAS号为 3080-29-3。
TNU0298 Adenosine-2-carboxamide

Others Others
Adenosine-2-carboxamide is a Nucleoside Derivative - 2-Modified purine nucleoside.
TNU0398 8-Methylthio-adenosine

Others Others
8-Methylthio-adenosine is a Nucleoside Derivative - 8-Modified purine nucleoside.
TNU0465 2-Aminomethyl   adenosine

Others Others
2-Aminomethyl adenosine is a Nucleoside Derivative - 2-Modified purine nucleoside.
TNU1117 2-Diethoxymethyl   adenosine

Others Others
2-Diethoxymethyl   adenosine 是一种有用的有机化合物,可用于生命科学领域的相关研究,其产品编号为 TNU1117。
TNU0327 2-Trifluoromethyl adenosine

Others Others
Nucleoside Derivatives –8-substituted purine nucleosides ;ara-nucleosides.
T16136 MRS-1706

Adenosine Receptor GPCR/G Protein; Neuroscience
MRS-1706 是一种选择性A2B 腺苷受体的反向激动剂,对人 A2B、A2A、A1和 A3受体的Ki 值分别为 1.39、112、157 和 230 nM。
T75208 2-Diethoxymethyl adenosine

Others Others
2-Diethoxymethyl adenosine 是一种腺嘌呤核苷类似物。腺苷类似物大多可作为平滑肌血管扩张剂,也被证明能够抑制癌症进展。它的热门产品有 Adenosine phosphate,Acadesine ,Clofarabine ,Fludarabine phosphate 和 Vidarabine 。
T37118 ADP-Glucose (sodium salt)

ADPG,Adenosine-5'-diphosphoglucose,ADP-Glucose (sodium salt)

Others Others
ADP-Glucose (ADPG) is an immediate precursor used in the biosynthesis, by glucose addition, of storage polysaccharides in plants, green algae, and cyanobacteria, as well as structural polysaccharides in certain bacteria.[1],[2] It is used by amylose synthases or starch synthases in plastids in the production of amylose, amylopectins, starch, and other polysaccharides. ADPG is normally generated within plastids, although it can be biosynthesized in the cytoplasm of certain grasses and imported in...
TNU0860 N6-Acetyl adenosine

Others Others
Nucleoside Derivatives –Naturally modified ribo-nucleosides;Other modified nucleosides
TNU1650 3’-O-Hexadecanyl adenosine

Others Others
3’-O-Hexadecanyl adenosine 是一种有用的有机化合物,可用于生命科学领域的相关研究,其产品编号为 TNU1650。

化合物

LNA-Adenosine
Cat.No: T32826
Synonym: LNA-A,LNA Adenosine,2'-O,4'-C-Methyleneadenosine
Target: Nucleoside Antimetabolite/Analog
Adenosine N1-oxide
Cat.No: T23636
Synonym: ANO,1-Oxoadenosine,Adenosine N1 oxide,Adenosine, 1-oxide,腺苷氮氧化物
Target: Immunology/Inflammation related
Adenosine Dialdehyde (ADOX)
Cat.No: T22231
Synonym: 腺苷二醛,Periodate-oxidized adenosine,Adenosine, periodate oxidized,Adenox,Adenosinedialdehyde
Target: Others
Adenosine 5'-monophosphate disodium salt
Cat.No: T65979
Synonym: Adenosine Phosphate Disodium,5‘-AMP-NA2
Target: Nucleoside Antimetabolite/Analog
Adenosine 5'-diphosphoribose sodium
Cat.No: T10247
Synonym: Adenosine 5'-diphosphoribose sodium,ADP ribose sodium
Target: Endogenous Metabolite, TRP/TRPV Channel, Autophagy
Adenosine amine congener
Cat.No: T7683
Synonym: ADAC
Target: Adenosine Receptor
Adenosine antagonist-1
Cat.No: T10248
Synonym:
Target: Adenosine Receptor
N6-(2-Phenylethyl)adenosine
Cat.No: T12163
Synonym: N6-Phenethyladenosine,N6-Phenylethyladenosine
Target: Adenosine Receptor
N6-(p-Hydroxyphenethyl)-Adenosine)
Cat.No: T60103
Synonym:
Target: Others
Adenosine A1 receptor activator T62
Cat.No: T14127
Synonym:
Target: Adenosine Receptor
N-[(4-Aminophenyl)methyl]adenosine
Cat.No: T16166
Synonym:
Target: Adenosine Receptor
Adenosine receptor A1 antagonist 5
Cat.No: T22466
Synonym:
Target: cAMP
Adenosine receptor antagonist 4
Cat.No: T21620
Synonym:
Target: Adenosine Receptor
5'-Fluoro-5'-deoxyadenosine
Cat.No: T60020
Synonym: 5'-Fluoro-5'-deoxy-adenosine
Target: Others
2-Ethynyl Adenosine
Cat.No: T29347
Synonym: 2-Ethynyl-Ade,2 Ethynyl Adenosine,2-Ethynyl-Adenosine
Target: Others
NITD008
Cat.No: T16325
Synonym: 7-Deaza-2'-C-acetylene-adenosine
Target: Others
MethADP
Cat.No: T12008
Synonym: Adenosine 5'-(α,β-methylene)diphosphate
Target: CD73
N6-Benzyl-5'-ethylcarboxamido adenosine
Cat.No: T39011
Synonym: N6-Benzyl-5'-ethylcarboxamido adenosine
Target: Others
Guanosine 5'-triphosphate-5'-adenosine
Cat.No: T38449
Synonym: GpppA,Guanosine 5'-triphosphate-5'-adenosine
Target: Others
A2AR-agonist-1
Cat.No: T10212
Synonym: N-(2-(1H-Indol-3-yl)ethyl)adenosine
Target: Others, Adenosine Receptor
N7-Methyl-guanosine-5'-triphosphate-5'-adenosine
Cat.No: T40721
Synonym: N7-Methyl-guanosine-5'-triphosphate-5'-adenosine,m7GpppA
Target: Others
N6-(m-Methoxybenzyl)adenosine
Cat.No: TNU0431
Synonym:
Target: Endogenous Metabolite
Adenosine 5’-methylenediphosphate (hydrate)
Cat.No: T35573
Synonym:
Target: Others
Adenosine deaminase
Cat.No: T19179
Synonym:
Target: Others
Adenosine-5'-O-(3-thiotriphosphate) sodium
Cat.No: T83827
Synonym: ATPγS,Adenosine 5'-(γ-thio)-triphosphate
Target: Others
N6-(2-Hydroxyethyl)adenosine
Cat.No: TNU0429
Synonym:
Target: Calcium Channel
N6-(p-Methoxybenzyl)adenosine
Cat.No: TNU0430
Synonym:
Target: Nucleoside Antimetabolite/Analog
2'-O-(2-Azidoethyl)adenosine
Cat.No: TNU0178
Synonym:
Target: Nucleoside Antimetabolite/Analog
Adenosine receptor antagonist 1
Cat.No: T40307
Synonym:
Target: Others
Adenosine 5'-phosphosulfate (sodium salt)
Cat.No: T35574
Synonym:
Target: Others
Adenosine 5'-succinate
Cat.No: T38416
Synonym:
Target: Others
Adenosine 3’-monophosphate (sodium salt hydrate)
Cat.No: T35571
Synonym:
Target: Others
Adenosine-5'-diphosphate disodium salt
Cat.No: T71927
Synonym:
Target: Others
Adenosine Kinase Inhibitor (hydrate)
Cat.No: T22554
Synonym:
Target: Others
ABT-702 hydrochloride
Cat.No: T84880
Synonym: Adenosine Kinase Inhibitor hydrochloride
Target: Others
Adenosine 3',5'-diphosphate sodium salt
Cat.No: T35572
Synonym: 3'-Phosphoadenosine 5'-phosphate
Target: Endogenous Metabolite
APNEA
Cat.No: T12159
Synonym: (2R,3R,4S,5R)-2-[6-[2-(4-aminophenyl)ethylamino]purin-9-yl]-5-(hydroxymethyl)oxolane-3,4-diol,N6-[2-(4-Aminophenyl)ethyl]adenosine,N6-[2-(4-氨基苯基)乙基]腺嘌呤
Target: Adenosine Receptor
5'-O-DMT-2'-O-TBDMS-N-Bz-Adenosine
Cat.No: T37146
Synonym:
Target: Others
alpha-Adenosine
Cat.No: TNU1637
Synonym:
Target: Others
L-Adenosine
Cat.No: T65008
Synonym:
Target: Others
Adenosine-2-carboxamide
Cat.No: TNU0298
Synonym:
Target: Others
8-Methylthio-adenosine
Cat.No: TNU0398
Synonym:
Target: Others
2-Aminomethyl   adenosine
Cat.No: TNU0465
Synonym:
Target: Others
2-Diethoxymethyl   adenosine
Cat.No: TNU1117
Synonym:
Target: Others
2-Trifluoromethyl adenosine
Cat.No: TNU0327
Synonym:
Target: Others
MRS-1706
Cat.No: T16136
Synonym:
Target: Adenosine Receptor
2-Diethoxymethyl adenosine
Cat.No: T75208
Synonym:
Target: Others
ADP-Glucose (sodium salt)
Cat.No: T37118
Synonym: ADPG,Adenosine-5'-diphosphoglucose,ADP-Glucose (sodium salt)
Target: Others
N6-Acetyl adenosine
Cat.No: TNU0860
Synonym:
Target: Others
3’-O-Hexadecanyl adenosine
Cat.No: TNU1650
Synonym:
Target: Others
Cat. No. Product Name Target Signaling Pathways
T0853 Adenosine

腺苷,D-Adenosine,Adenine riboside

Apoptosis; Nucleoside Antimetabolite/Analog; Endogenous Metabolite; Autophagy Apoptosis; Autophagy; Cell Cycle/Checkpoint; DNA Damage/DNA Repair; Metabolism
Adenosine (D-Adenosine) 是一种核糖核苷,由与核糖结合的腺嘌呤组成,具有血管扩张、抗心律失常和镇痛作用。
T1723 Adenosine 5'-diphosphate

腺苷5'-二磷酸,Adenosine diphosphate,adenosine pyrophosphate,ADP

Endogenous Metabolite Metabolism
Adenosine 5'-diphosphate (ADP) 是一种嘌呤核糖核苷5'-二磷酸,是 ATP 在 ATP 酶作用下去磷酸化的产物。Adenosine 5'-diphosphate (adenosine pyrophosphate) 可诱导人血小板聚集并通过作用于P2T-嘌呤受体抑制受刺激的腺苷酸环化酶。
T2133 Adenosine monophosphate

5'-Adenylic acid,5'-腺嘌呤核苷酸,AMP,Adenosine 5'-monophosphate

Endogenous Metabolite; AMPK Chromatin/Epigenetic; Metabolism; PI3K/Akt/mTOR signaling
Adenosine monophosphate (AMP) 是一种嘌呤核糖核苷5'-单磷酸腺苷,是信号转导和调节能量稳态的关键细胞代谢物。它具有EC 3.1.3.11(果糖-二磷酸酶)抑制剂、EC 3.1.3.1(碱性磷酸酶)抑制剂和腺苷A1受体激动剂的作用。
T5079 Adenosine 5'-diphosphate sodium salt

腺苷-5‘-二磷酸钠盐,Adenosine-5'-diphosphate trisodium salt,ADP sodium salt

Others; Endogenous Metabolite Metabolism; Others
Adenosine 5'-diphosphate sodium salt (ADP sodium salt) 是一种核苷二磷酸,是一种 ATP 酶对 ATP 去磷酸化的产物。它通过在 P2T-嘌呤受体上的作用诱导人血小板聚集并抑制刺激的腺苷酸环化酶。
T12164 N6-(4-Hydroxybenzyl)adenosine

Para-topolin riboside,N6-羟苄腺苷

P2Y Receptor GPCR/G Protein; Neuroscience
N6-(4-Hydroxybenzyl)adenosine (Para-topolin riboside) 是一种血小板聚集抑制剂。
T0853L Adenosine 5'-monophosphate monohydrate

5'-AMP,腺苷-5'-单磷酸一水合物,5'-AMP monohydrate,5'-Adenylic acid

AMPK; Adenosine Receptor; HSV Chromatin/Epigenetic; GPCR/G Protein; Microbiology/Virology; Neuroscience; PI3K/Akt/mTOR signaling
Adenosine 5'-monophosphate monohydrate (5'-AMP) 是一种核苷酸,用作 RNA 中的单体。它是一个腺苷 A1受体激动剂,对HSV-1和HSV-2具有显著的抗病毒活性。
T34698 Spongosine

2-Methoxy adenosine

Others Others
Spongosine (2-Methoxy adenosine) 是一种重要的细胞间信号递质,具有多种生物活性,包括抗炎活性、镇痛和血管舒张特性。Spongosine 是从海洋生物中分离出来的天然产物,于1950年首次从海洋海绵隐毛隐(Cryptotethia crypta)中分离出来。
T64980 ATP disodium trihydrate

Adenosine-5'-triphosphate disodium trihydrate

Endogenous Metabolite Metabolism
ATP disodium trihydrate (Adenosine-5'-triphosphate disodium trihydrate) 是体内能量储存和代谢的重要物质,是免疫和炎症中重要的内源性信号分子,可为机体代谢提供能量,同时在细胞中作为辅酶发挥作用。
T20089 ATP

Atipi,ATP disodium salt hydrate,Triphosphoric acid adenosine ester,Ara-ATP,Triphosphaden,Adenosine triphosphate;Ara-ATP,Adenosine triphosphate

Endogenous Metabolite Metabolism
ATP (Adenosine triphosphate) 可为细胞提供能量,参与整体能量平衡,维持细胞内稳态。ATP 可以通过与特异性嘌呤能受体的相互作用充当细胞外信号分子,以介导神经传递、炎症、细胞凋亡和骨重塑等多种过程。
TCO2745 Cyclic AMP

Adenosine 3',5'-cyclophosphate,cAMP,腺苷环磷酸酯,环磷腺苷,Cyclic 3',5'-monophosphate adenosine,3',5'-AMP,Adenosine Cyclophosphate

Others; Endogenous Metabolite Metabolism; Others
Cyclic AMP (cAMP)(Adenosine 3',5'-cyclophosphate) 是有丝分裂信使,可以促进 G1期到 S 期的细胞周期进程。
TN7208 2-Methyladenosine

2-methyl adenosine,2-甲基腺苷

Others Others
2-Methyladenosine (2-methyl adenosine) 是一种海洋来源的天然产物,存在于Family Tethyidae。
T1352 ATP disodium salt

Adenosine 5'-triphosphate disodium salt,三磷酸腺苷二钠,ATP,ATP disodium,腺苷-5'-三磷酸二钠盐,Adetide,Adenosine-Triphosphate,Disodium adenosine triphosphate

P2X Receptor; Endogenous Metabolite Membrane transporter/Ion channel; Metabolism; Neuroscience
ATP disodium salt (Adenosine-Triphosphate) 是体内能量储存的重要物质,为代谢提供能量,同时在细胞中作为辅酶发挥作用。Adenosine 5'-triphosphate disodium salt 也是免疫和炎症中重要的内源性信号分子。
T2812 ATP disodium salt hydrate

ATP disodium,ATP disodium salt,Adenosine disodium triphosphate,三磷酸腺苷二钠盐

Others; Endogenous Metabolite Metabolism; Others
ATP disodium salt hydrate (Adenosine disodium triphosphate) 是体内能量储存和代谢的重要物质,为代谢提供能量,同时在细胞中作为辅酶发挥作用。同时,它是也是免疫和炎症中重要的内源性信号分子。
T38415 Adenosine 5′-monophosphoramidate sodium

Others Others
Adenosine 5′-monophosphoramidate sodium is a derivative of adenosine used as an intermediate for nucleotide synthesis. It significantly influences the accumulation of cyclic AMP.
T39025 Adenosine 2',5'-diphosphate sodium

Others Others
Adenosine 2',5'-diphosphate sodium is a competitive P2Y1 antagonist with non-selective antagonism at recombinant and human platelet P2X1 receptors.
T20054 Adenosine-2'-monophosphate

2'-Adenylic acid

Others Others
2'-Adenylic acid is an agent of bioactive chemical.
T8227 5'-Methylthioadenosine

Methylthioadenosine,5-脱氧-5-甲硫腺苷,5'-(Methylthio)-5'-deoxyadenosine,5'-Deoxy-5'-(methylthio)adenosine,5'-S-Methyl-5'-thioadenosine

Endogenous Metabolite Metabolism
5'-Methylthioadenosine 是由 S-腺苷蛋氨酸在多胺合成过程中生成的核苷,通过抑制肿瘤细胞增殖、侵袭和诱导细胞凋亡来抑制肿瘤,同时控制肿瘤组织的炎症微环境。
TN2247 Swertisin

Adenosine Receptor GPCR/G Protein; Neuroscience
Swertisin 是从日本紫菜中分离出的 C-葡萄糖基黄酮,是腺苷 A1 受体拮抗剂,具有抗糖尿病、抗炎和抗氧化作用。
T0437 Inosine

INO 495,NSC 20262,肌苷

ROS; Endogenous Metabolite; Adenosine Receptor GPCR/G Protein; Immunology/Inflammation; Metabolism; Neuroscience
Inosine (NSC-20262) 是由腺苷分解代谢产生的一种内源性嘌呤核苷,是腺苷受体A1R 和A2AR 的激动剂,具有抗炎免疫调节,抗伤害和神经保护作用。
TN1736 Hibifolin

棉皮素-8-O-Β-D-葡萄糖醛酸苷,棉花皮素-8-O-葡萄糖醛酸苷

Adenosine deaminase Metabolism
Hibifolin 是一种黄酮醇糖苷,是潜在的腺苷脱氨酶抑制剂。它可以保护神经元免受 beta-淀粉样蛋白诱导的毒性。
T1681 Aminophylline

氨茶碱,Phyllocontin

PDE; Adenosine Receptor GPCR/G Protein; Metabolism; Neuroscience
Aminophylline (Phyllocontin) 是一种竞争性非选择性磷酸二酯酶抑制剂,具有支气管扩张作用。它是竞争性的腺苷受体拮抗剂,有用于哮喘研究的潜力。
T0892 Diphylline

二羟丙茶碱,Dyphylline,Diprophylline

PDE; Adenosine Receptor GPCR/G Protein; Metabolism; Neuroscience
Diphylline (Diprophylline) 是一种A1/A2腺苷受体拮抗剂,也是环状核苷酸磷酸二酯酶抑制剂。它是一种黄嘌呤衍生物,具有支气管扩张和血管扩张作用,有用于治疗慢性支气管炎和肺气肿的潜力。
T5940 Proxyphylline

羟丙茶碱,7-(2-Hydroxypropyl)theophylline

PDE; Adenosine Receptor GPCR/G Protein; Metabolism; Neuroscience
Proxyphylline (7-(2-Hydroxypropyl)theophylline) 是甲基黄嘌呤衍生物,可用作心脏活化剂、血管扩张剂和支气管扩张剂。
T0625 Theobromine

3, 7-Dimethylxanthine,可可碱,3,7-Dimethylxanthine

Endogenous Metabolite; PDE; Adenosine Receptor GPCR/G Protein; Metabolism; Neuroscience
Theobromine (3,7-Dimethylxanthine) 是在可可豆中发现的一种甲基黄嘌呤,抑制腺苷受体 A1 信号传导,用作支气管扩张剂和血管扩张剂。
T5S1895 Norisoboldine

Laurelliptine,去甲异波尔定,(+)-Laurelliptine

MAPK; Adenosine Receptor GPCR/G Protein; MAPK; Neuroscience
Norisoboldine ((+)-Laurelliptine) 是一种可口服的芳基烃受体激动剂,是乌药中主要的异喹啉类生物碱,可用于类风湿性关节炎和溃疡性结肠炎的研究。
T0480 Doxofylline

Doxophylline,多索茶碱

PDE; Adenosine Receptor GPCR/G Protein; Metabolism; Neuroscience
Doxofylline (Doxophylline) 是腺苷 A1 受体拮抗剂,且能抑制磷酸二酯酶 IV,用于治疗哮喘。
T1083 Theophylline

Theo-24,1,3-Dimethylxanthine,茶碱

Endogenous Metabolite; HDAC; PDE; Adenosine Receptor; Autophagy Autophagy; Chromatin/Epigenetic; DNA Damage/DNA Repair; GPCR/G Protein; Metabolism; Neuroscience
Theophylline (1,3-Dimethylxanthine) 是茶中的甲基黄嘌呤衍生物,具有利尿、平滑肌松弛、支气管扩张、心脏和中枢神经系统兴奋作用。
T2205 Acefylline

Theophylline-7-acetic acid,茶碱乙酸,Carboxymethyltheophylline,acetyloxytheophylline,Theophyllineacetic acid

TNF; PAD; PKA; HDAC; PDE; Adenosine Receptor Apoptosis; Chromatin/Epigenetic; DNA Damage/DNA Repair; GPCR/G Protein; Metabolism; Neuroscience; Tyrosine Kinase/Adaptors
Acefylline (Theophylline-7-acetic acid) 是黄嘌呤衍生物,是一种腺苷受体拮抗剂。它是蛋白质精氨酸脱亚氨酶 (PAD) 激活剂,也是一种支气管扩张剂,可抑制大鼠肺 cAMP 磷酸二酯酶同工酶。
T17143 Toyocamycin

丰加霉素,Vengicide

Apoptosis; Others; IRE1; Antibiotic; Antifungal Apoptosis; Cell Cycle/Checkpoint; Microbiology/Virology; Others
Toyocamycin (Vengicide) 是放线菌类产生的腺苷类似物,为 X 盒结合蛋白 1 (XBP1) 抑制剂,抑制 IRE1α 诱导的 ATP 依赖性 XBP1 mRNA 的断裂,IC50值为 80 nM。它还诱导凋亡。
T40370 2′-Deoxyadenosine 5′-monophosphate disodium

Endogenous Metabolite Metabolism
2′-Deoxyadenosine 5′-monophosphate disodium, a nucleic acid AMP derivative, is a deoxyribonucleotide present in DNA. It is employed for researching adenosine-based interactions within DNA synthesis and damage analysis.
T13482 2'-O-Methyladenosine

Endogenous Metabolite Metabolism
2'-O-Methyladenosine 是甲基化腺嘌呤的残基,在正常人群和腺苷脱氨基酶缺乏病人的尿液中均可被检测到。它显示出独特的降血压活性。
T2752 2'-Deoxyadenosine monohydrate

Others; Endogenous Metabolite Metabolism; Others
2'-Deoxyadenosine monohydrate 是化学合成中的砌块,是一种脱氧核糖核苷。
T4737 2'-Deoxyadenosine-5'-monophosphate

D-AMP,2′-脱氧腺苷-5′-单磷酸,2'-Deoxyadenosine 5'-monophosphate,2'-脱氧腺苷-5'-单磷酸

Others; Endogenous Metabolite Metabolism; Others
2'-Deoxyadenosine-5'-monophosphate (D-AMP) 是一种存在于 DNA 中的脱氧核糖核苷酸,是一种核酸 AMP 衍生物。它能够用于研究 DNA 合成和 DNA 损伤过程中基于腺苷的相互作用。
T4971 5'-DEOXYADENOSINE

5′-dAdo,5-脱氧腺嘌呤核苷

Endogenous Metabolite Metabolism
5'-Deoxyadenosine (5′-dAdo) 是正常受试者尿液中发现的氧化核苷,氧化核苷代表了用于确定遗传物质损伤程度的生物标志物。
T20041 2'-Deoxyadenosine

2'-脱氧腺苷,NSC-141848,NSC141848,NSC 141848

Endogenous Metabolite Metabolism
2'-Deoxyadenosine (NSC-141848) 是核苷腺苷的一种衍生物,能够与双链 DNA 中的脱氧胸苷配对。
T7981 2-Fluoroadenosine

Others Others
2-Fluoroadenosine 是淋巴细胞介导的细胞溶解的有效抑制剂。
T6599 N6-methyladenosine

N6-甲基腺苷,N-Methyladenosine,6-Methyladenosine,NSC-29409,m6A

Others; Influenza Virus; Endogenous Metabolite Metabolism; Microbiology/Virology; Others
N6-Methyladenosine 是甲基化的腺嘌呤残基,苷是转移核糖核酸降解的内源性尿核苷产物。它是存在于所有高等真核生物中最普遍的的信使 RNA 内部修饰,可修饰病毒 RNA,有抗病毒活性。
T7571 1-Methyladenosine

Endogenous Metabolite Metabolism
1-Methyladenosine 是 RNA 修饰,主要来自两种不同的反应类型,酶催化反应以及 RNA 与某些烷化剂反应。
T37635 2'-Deoxyadenosine-5'-triphosphate trisodium

dATP trisodium

DNA/RNA Synthesis; Endogenous Metabolite Cell Cycle/Checkpoint; DNA Damage/DNA Repair; Metabolism
2'-Deoxyadenosine-5'-triphosphate trisodium (dATP trisodium) 是一种核苷酸,是 DNA 聚合酶的底物,在细胞中用于 DNA 合成或复制。
T40483 8-Aminoadenosine

8-NH2-Ado,8-氨基腺苷

Others Others
8-Aminoadenosine (8-NH2-Ado) is an RNA-directed nucleoside analogue that effectively diminishes cellular ATP levels and impedes mRNA synthesis. Furthermore, it effectively obstructs Akt/mTOR signaling, inducing autophagy and apoptosis in a p53-independent manner. Its significant antitumor activity further highlights its therapeutic potential.
T83789 7-Deazaadenosine-5'-O-diphosphate sodium

7-CH-ADP,Tubercidin 5’-diphosphate,TuDP

Others Others
7-Deazaadenosine-5'-O-diphosphate是一种修饰过的核苷酸和tubercidin的代谢物。该化合物通过磷酸化tubercidin形成,并进一步磷酸化生成活性代谢物7-deazaadenosine-5'-O-triphosphate。
T36667 2'-Deoxyadenosine-5'-triphosphate

dATP,Deoxyadenosine 5-triphosphate

DNA/RNA Synthesis; Endogenous Metabolite Cell Cycle/Checkpoint; DNA Damage/DNA Repair; Metabolism
2'-Deoxyadenosine-5'-triphosphate (Deoxyadenosine 5-triphosphate) (dATP) 是一种天然存在的小分子核苷酸,在细胞中用于DNA合成或复制。2'-Deoxyadenosine-5'-triphosphate (dATP) 是 DNA 聚合酶的底物。2'-Deoxyadenosine-5'-triphosphate 通过无活性的 α4beta4 四级结构抑制RNA。2'-Deoxyadenosine-5'-triphosphate 与心肌细胞生长有关。
T37977 Succinyladenosine

Others Others
Succinyladenosine is a biochemical marker of adenylosuccinase (ASL) deficiency. It is formed through the dephosphorylation of intracellular adenylosuccinic acid (S-AMP) by cytosolic 5-nucleotidase [1].
T7327 7-Methoxyisoflavone

AMPK Chromatin/Epigenetic; PI3K/Akt/mTOR signaling
7-Methoxyisoflavone 是单磷酸腺苷活化蛋白激酶 (AMPK) 的激活剂,是异黄酮衍生物。
T0543 7-Methylxanthine

Heteroxanthine,Heteroxanthin,7-甲基黄嘌呤

Nucleoside Antimetabolite/Analog; Endogenous Metabolite; Adenosine Receptor Cell Cycle/Checkpoint; DNA Damage/DNA Repair; GPCR/G Protein; Metabolism; Neuroscience
7-Methylxanthine 是一种黄嘌呤的甲基衍生物,是人尿结石的嘌呤成分。7-Methylxanthine 对腺苷受体有亲和力。
T14149 AICAR phosphate

AICA Riboside phosphate,Acadesine phosphate

Mitophagy; NOS; YAP; AMPK Autophagy; Chromatin/Epigenetic; Immunology/Inflammation; PI3K/Akt/mTOR signaling; Stem Cells
AICAR phosphate (Acadesine phosphate) 是 AMPK 激活剂且是自噬、YAP 和 mitophagy 抑制剂,也是一种腺苷类似物, 可调节糖代谢和脂代谢,抑制促炎细胞因子和 iNOS 的产生。
T4S0792 Pinoresinol 4-O-β-D-glucopyranoside

(+)-pinor,(+)-pinoresinol-β-D-glucoside; (+)-pinor,(+)-pinoresinol-β-D-glucoside

Others; Antioxidant Others; oxidation-reduction
(+)-pinoresinol-β-D-glucoside; (+)-pinor 是连翘中主要的活性呋喃类木脂素。它显示出抗氧化、降血压和环磷酸腺苷 (cAMP) 磷酸二酯酶抑制活性。
T10822 Cirsimarin

Cirsitakaoside

Adenosine Receptor GPCR/G Protein; Neuroscience
Cirsimarin (Cirsitakaoside) 是一种从 Microtea debilis 中分离出来的黄酮类化合物。它具有很强的抗脂肪生成作用,能减少小鼠脂肪组织的沉积。Cirsimarin 对腺苷 A1 受体有拮抗作用,对磷酸二酯酶有抑制作用
T3S0156 Atractyloside potassium salt

Atractyloside Dipotassium Salt,苍术苷钾盐,苍术苷二钾盐

Others Others
Atractyloside potassium salt (Atractyloside Dipotassium Salt) 是一种从苍术果实中分离出得到的二萜苷类化合物,具有毒性。它能抑制大鼠心脏线粒体膜的氯离子通道。它是高效、特异性的线粒体 ADP/ATP 转运 (ADP/ATP transport) 抑制剂。
T7004 Tubercidin

结核菌素,杀结核菌素,Sparsomycin A,7-Deazaadenosine

Influenza Virus; DNA/RNA Synthesis; Antibacterial; Antibiotic Cell Cycle/Checkpoint; DNA Damage/DNA Repair; Microbiology/Virology
Tubercidin (Sparsomycin A) 是从Streptomyces tubercidicus 得到的抗生素,抑制粪链球菌生长的IC50值为 0.02 μM。它是腺苷磷酸化酶的弱抑制剂,并干扰腺苷和 AMP 的磷酸化。它有抗病毒作用。
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天然产物

Adenosine
Cat.No: T0853
Synonym: 腺苷,D-Adenosine,Adenine riboside
Target: Apoptosis, Nucleoside Antimetabolite/Analog, Endogenous Metabolite, Autophagy
Adenosine 5'-diphosphate
Cat.No: T1723
Synonym: 腺苷5'-二磷酸,Adenosine diphosphate,adenosine pyrophosphate,ADP
Target: Endogenous Metabolite
Adenosine monophosphate
Cat.No: T2133
Synonym: 5'-Adenylic acid,5'-腺嘌呤核苷酸,AMP,Adenosine 5'-monophosphate
Target: Endogenous Metabolite, AMPK
Adenosine 5'-diphosphate sodium salt
Cat.No: T5079
Synonym: 腺苷-5‘-二磷酸钠盐,Adenosine-5'-diphosphate trisodium salt,ADP sodium salt
Target: Others, Endogenous Metabolite
N6-(4-Hydroxybenzyl)adenosine
Cat.No: T12164
Synonym: Para-topolin riboside,N6-羟苄腺苷
Target: P2Y Receptor
Adenosine 5'-monophosphate monohydrate
Cat.No: T0853L
Synonym: 5'-AMP,腺苷-5'-单磷酸一水合物,5'-AMP monohydrate,5'-Adenylic acid
Target: AMPK, Adenosine Receptor, HSV
Spongosine
Cat.No: T34698
Synonym: 2-Methoxy adenosine
Target: Others
ATP disodium trihydrate
Cat.No: T64980
Synonym: Adenosine-5'-triphosphate disodium trihydrate
Target: Endogenous Metabolite
ATP
Cat.No: T20089
Synonym: Atipi,ATP disodium salt hydrate,Triphosphoric acid adenosine ester,Ara-ATP,Triphosphaden,Adenosine triphosphate;Ara-ATP,Adenosine triphosphate
Target: Endogenous Metabolite
Cyclic AMP
Cat.No: TCO2745
Synonym: Adenosine 3',5'-cyclophosphate,cAMP,腺苷环磷酸酯,环磷腺苷,Cyclic 3',5'-monophosphate adenosine,3',5'-AMP,Adenosine Cyclophosphate
Target: Others, Endogenous Metabolite
2-Methyladenosine
Cat.No: TN7208
Synonym: 2-methyl adenosine,2-甲基腺苷
Target: Others
ATP disodium salt
Cat.No: T1352
Synonym: Adenosine 5'-triphosphate disodium salt,三磷酸腺苷二钠,ATP,ATP disodium,腺苷-5'-三磷酸二钠盐,Adetide,Adenosine-Triphosphate,Disodium adenosine triphosphate
Target: P2X Receptor, Endogenous Metabolite
ATP disodium salt hydrate
Cat.No: T2812
Synonym: ATP disodium,ATP disodium salt,Adenosine disodium triphosphate,三磷酸腺苷二钠盐
Target: Others, Endogenous Metabolite
Adenosine 5′-monophosphoramidate sodium
Cat.No: T38415
Synonym:
Target: Others
Adenosine 2',5'-diphosphate sodium
Cat.No: T39025
Synonym:
Target: Others
Adenosine-2'-monophosphate
Cat.No: T20054
Synonym: 2'-Adenylic acid
Target: Others
5'-Methylthioadenosine
Cat.No: T8227
Synonym: Methylthioadenosine,5-脱氧-5-甲硫腺苷,5'-(Methylthio)-5'-deoxyadenosine,5'-Deoxy-5'-(methylthio)adenosine,5'-S-Methyl-5'-thioadenosine
Target: Endogenous Metabolite
Swertisin
Cat.No: TN2247
Synonym:
Target: Adenosine Receptor
Inosine
Cat.No: T0437
Synonym: INO 495,NSC 20262,肌苷
Target: ROS, Endogenous Metabolite, Adenosine Receptor
Hibifolin
Cat.No: TN1736
Synonym: 棉皮素-8-O-Β-D-葡萄糖醛酸苷,棉花皮素-8-O-葡萄糖醛酸苷
Target: Adenosine deaminase
Aminophylline
Cat.No: T1681
Synonym: 氨茶碱,Phyllocontin
Target: PDE, Adenosine Receptor
Diphylline
Cat.No: T0892
Synonym: 二羟丙茶碱,Dyphylline,Diprophylline
Target: PDE, Adenosine Receptor
Proxyphylline
Cat.No: T5940
Synonym: 羟丙茶碱,7-(2-Hydroxypropyl)theophylline
Target: PDE, Adenosine Receptor
Theobromine
Cat.No: T0625
Synonym: 3, 7-Dimethylxanthine,可可碱,3,7-Dimethylxanthine
Target: Endogenous Metabolite, PDE, Adenosine Receptor
Norisoboldine
Cat.No: T5S1895
Synonym: Laurelliptine,去甲异波尔定,(+)-Laurelliptine
Target: MAPK, Adenosine Receptor
Doxofylline
Cat.No: T0480
Synonym: Doxophylline,多索茶碱
Target: PDE, Adenosine Receptor
Theophylline
Cat.No: T1083
Synonym: Theo-24,1,3-Dimethylxanthine,茶碱
Target: Endogenous Metabolite, HDAC, PDE, Adenosine Receptor, Autophagy
Acefylline
Cat.No: T2205
Synonym: Theophylline-7-acetic acid,茶碱乙酸,Carboxymethyltheophylline,acetyloxytheophylline,Theophyllineacetic acid
Target: TNF, PAD, PKA, HDAC, PDE, Adenosine Receptor
Toyocamycin
Cat.No: T17143
Synonym: 丰加霉素,Vengicide
Target: Apoptosis, Others, IRE1, Antibiotic, Antifungal
2′-Deoxyadenosine 5′-monophosphate disodium
Cat.No: T40370
Synonym:
Target: Endogenous Metabolite
2'-O-Methyladenosine
Cat.No: T13482
Synonym:
Target: Endogenous Metabolite
2'-Deoxyadenosine monohydrate
Cat.No: T2752
Synonym:
Target: Others, Endogenous Metabolite
2'-Deoxyadenosine-5'-monophosphate
Cat.No: T4737
Synonym: D-AMP,2′-脱氧腺苷-5′-单磷酸,2'-Deoxyadenosine 5'-monophosphate,2'-脱氧腺苷-5'-单磷酸
Target: Others, Endogenous Metabolite
5'-DEOXYADENOSINE
Cat.No: T4971
Synonym: 5′-dAdo,5-脱氧腺嘌呤核苷
Target: Endogenous Metabolite
2'-Deoxyadenosine
Cat.No: T20041
Synonym: 2'-脱氧腺苷,NSC-141848,NSC141848,NSC 141848
Target: Endogenous Metabolite
2-Fluoroadenosine
Cat.No: T7981
Synonym:
Target: Others
N6-methyladenosine
Cat.No: T6599
Synonym: N6-甲基腺苷,N-Methyladenosine,6-Methyladenosine,NSC-29409,m6A
Target: Others, Influenza Virus, Endogenous Metabolite
1-Methyladenosine
Cat.No: T7571
Synonym:
Target: Endogenous Metabolite
2'-Deoxyadenosine-5'-triphosphate trisodium
Cat.No: T37635
Synonym: dATP trisodium
Target: DNA/RNA Synthesis, Endogenous Metabolite
8-Aminoadenosine
Cat.No: T40483
Synonym: 8-NH2-Ado,8-氨基腺苷
Target: Others
7-Deazaadenosine-5'-O-diphosphate sodium
Cat.No: T83789
Synonym: 7-CH-ADP,Tubercidin 5’-diphosphate,TuDP
Target: Others
2'-Deoxyadenosine-5'-triphosphate
Cat.No: T36667
Synonym: dATP,Deoxyadenosine 5-triphosphate
Target: DNA/RNA Synthesis, Endogenous Metabolite
Succinyladenosine
Cat.No: T37977
Synonym:
Target: Others
7-Methoxyisoflavone
Cat.No: T7327
Synonym:
Target: AMPK
7-Methylxanthine
Cat.No: T0543
Synonym: Heteroxanthine,Heteroxanthin,7-甲基黄嘌呤
Target: Nucleoside Antimetabolite/Analog, Endogenous Metabolite, Adenosine Receptor
AICAR phosphate
Cat.No: T14149
Synonym: AICA Riboside phosphate,Acadesine phosphate
Target: Mitophagy, NOS, YAP, AMPK
Pinoresinol 4-O-β-D-glucopyranoside
Cat.No: T4S0792
Synonym: (+)-pinor,(+)-pinoresinol-β-D-glucoside; (+)-pinor,(+)-pinoresinol-β-D-glucoside
Target: Others, Antioxidant
Cirsimarin
Cat.No: T10822
Synonym: Cirsitakaoside
Target: Adenosine Receptor
Atractyloside potassium salt
Cat.No: T3S0156
Synonym: Atractyloside Dipotassium Salt,苍术苷钾盐,苍术苷二钾盐
Target: Others
Tubercidin
Cat.No: T7004
Synonym: 结核菌素,杀结核菌素,Sparsomycin A,7-Deazaadenosine
Target: Influenza Virus, DNA/RNA Synthesis, Antibacterial, Antibiotic
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Cat. No. Product Name Species Expression System
TMPY-03985 Adenosine Deaminase Protein, Human, Recombinant (His)

ADA1,adenosine deaminase,ADA

Human Baculovirus Insect Cells
Adenosine Desaminase (ADA) deficiency, is a purine metabolic disorder that cause severe combined immunodeficiency (SCID) due to the accumulation of toxic metabolites that primarily affects development, differentiation and function of T and B lymphocytes. Adenosine deaminase is a polymorphic enzyme that has an important role in immune functions and in the regulation of intracellular and extracellular concentrations of adenosine and adenosine receptor activity. ADA activity might be considered as...
TMPY-04473 ADK Protein, Human, Recombinant (His & GST)

adenosine kinase,AK

Human Baculovirus Insect Cells
Adenosine kinase(ADK) belongs to the family of transferases. Adenosine kinase (ADK) is the key enzyme in adenosine metabolism and catalyzes ATP and adenosine into two products: ADP and AMP. Two isoforms of the enzyme adenosine kinase (ADK), which differ at their N-terminal ends, are found in mammalian cells. It has been shown that the two ADK isoforms differ only in their first exons and the promoter regions; hence they arise via differential splicing of their first exons with the other exons co...
TMPH-00892 A1AR Protein, Human, Recombinant (His)

Adenosine receptor A1,ADORA1

Human E. coli
Receptor for adenosine. The activity of this receptor is mediated by G proteins which inhibit adenylyl cyclase. A1AR Protein, Human, Recombinant (His) is expressed in E. coli expression system with N-10xHis tag. The predicted molecular weight is 39.3 kDa and the accession number is P30542.
TMPY-00516 CECR1 Protein, Human, Recombinant (His)

adenosine deaminase 2,ADA2,IDGFL,ADGF,CECR1

Human Baculovirus Insect Cells
CECR1 Protein, Human, Recombinant (His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 57.3 kDa and the accession number is AAH51755.1.
TMPH-01734 METTL3 Protein, Human, Recombinant (His)

METTL3,N6-adenosine-methyltransferase catalytic sub...

Human E. coli
METTL3 Protein, Human, Recombinant (His) is expressed in E. coli expression system with N-10xHis tag. The predicted molecular weight is 70.4 kDa and the accession number is Q86U44.
TMPK-00861 A2AR Protein-VLP, Human, Recombinant

RDC8,Adenosine A2a R,ADORA2,ADORA 2,ADORA2A,A2aR

Human HEK293 Cells
Adenosine is a neuromodulator in the adult central nervous system. Membrane-bound receptors for adenosine have been identified and cDNAs for A1, A2a, A2b, and A3 adenosine receptor subtypes have been cloned recently.Expression of A2a adenosine receptor mRNA in cranial ganglia, carotid body, and intermediate lobe of the pituitary gland similarly suggests novel sites of adenosine action during development and in the adult.
TMPH-03205 HINT1 Protein, Rabbit, Recombinant (His & Myc)

HINT1,Histidine triad nucleotide-binding protein 1,Desumoyla...

Rabbit HEK293 Cells
HINT1 Protein, Rabbit, Recombinant (His & Myc) is expressed in HEK293 mammalian cells with N-10xHis and C-Myc tag. The predicted molecular weight is 17.6 kDa and the accession number is P80912.
TMPH-01248 ADAR Protein, Human, Recombinant (His & SUMO)

ADAR1,IFI-4,136 kDa double-stranded RNA-binding protein,Inte...

Human E. coli
Catalyzes the hydrolytic deamination of adenosine to inosine in double-stranded RNA (dsRNA) referred to as A-to-I RNA editing. This may affect gene expression and function in a number of ways that include mRNA translation by changing codons and hence the amino acid sequence of proteins; pre-mRNA splicing by altering splice site recognition sequences; RNA stability by changing sequences involved in nuclease recognition; genetic stability in the case of RNA virus genomes by changing sequences duri...
TMPH-01249 ADAR Protein, Human, Recombinant (GST)

DRADA,K88DSRBP,p136,136 kDa double-stranded RNA-binding prot...

Human E. coli
ADAR Protein, Human, Recombinant (GST) is expressed in E. coli expression system with N-GST tag. The predicted molecular weight is 47.2 kDa and the accession number is P55265.
TMPH-02549 FHIT Protein, Mouse, Recombinant (His)

Adenylylsulfatase,Adenylylsulfate-ammonia adenylyltransferas...

Mouse E. coli
Possesses dinucleoside triphosphate hydrolase activity. Cleaves P(1)-P(3)-bis(5'-adenosyl) triphosphate (Ap3A) to yield AMP and ADP. Can also hydrolyze P(1)-P(4)-bis(5'-adenosyl) tetraphosphate (Ap4A), but has extremely low activity with ATP. Exhibits adenylylsulfatase activity, hydrolyzing adenosine 5'-phosphosulfate to yield AMP and sulfate. Exhibits adenosine 5'-monophosphoramidase activity, hydrolyzing purine nucleotide phosphoramidates with a single phosphate group such as adenosine 5'monop...
TMPY-04762 CKM Protein, Human, Recombinant (His)

creatine kinase, muscle,M-CK,CKMM

Human E. coli
CKM, also known as CK-MM, is mainly expressed in skeletal muscle. As the primary CK isoenzyme, it also can be detected in heart muscle. CKM is a subunit of creatine kinase (CK). CK is an enzyme expressed by various tissues and cell types. It catalyses the conversion of creatine and consumes adenosine triphosphate (ATP) to create phosphocreatine and adenosine diphosphate (ADP). In the cells, the cytosolic CK enzymes consist of two subunits, which can be either B (brain type) or M (muscle type).
TMPH-00745 TsaE Protein, E. coli, Recombinant

t(6)A37 threonylcarbamoyladenosine biosynthesis pro...

E. coli E. coli
Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaD and TsaB. TsaE seems to play an indirect role in the t(6)A biosynthesis pathway, possibly in regulating the core enzymatic function of TsaD. Displays ATPase activity in vitro.
TMPY-03417 ACBD7 Protein, Human, Recombinant (His)

acyl-CoA binding domain containing 7,ACBD7,bA455B2.2,RP11-45...

Human E. coli
ACBD7, acyl-CoA-binding domain-containing protein 7, is a small (1 Kd) protein that contains 1 ACB (acyl-CoA-binding) domain. The ACB domain consists of four alpha-helices arranged in a bowl shape with a highly exposed acyl-CoA-binding site. The ligand is bound through specific interactions with residues on the protein, most notably several conserved positive charges that interact with the phosphate group on the adenosine-3'phosphate moiety, and the acyl chain is sandwiched between the hydrop...
TMPY-02977 PDE1C Protein, Human, Recombinant (His & GST)

hCam-3,phosphodiesterase 1C, calmodulin-dependent 70kDa,cam-...

Human Baculovirus Insect Cells
PDE1C belongs to the cyclic nucleotide phosphodiesterase family, PDE1 subfamily. Phosphodiesterases (PDEs) are a family of related phosphohydrolyases that selectively catalyze the hydrolysis of 3' cyclic phosphate bonds in adenosine and/or guanine 3',5' cyclic monophosphate (cAMP and/or cGMP). They regulate the cellular levels, localization and duration of action of these second messengers by controlling the rate of their degradation. PDEs are expressed ubiquitously, with each subtype having a s...

重组蛋白

Adenosine Deaminase Protein, Human, Recombinant (His)
Cat.No: TMPY-03985
Species: Human
Expression System: Baculovirus Insect Cells
ADK Protein, Human, Recombinant (His & GST)
Cat.No: TMPY-04473
Species: Human
Expression System: Baculovirus Insect Cells
A1AR Protein, Human, Recombinant (His)
Cat.No: TMPH-00892
Species: Human
Expression System: E. coli
CECR1 Protein, Human, Recombinant (His)
Cat.No: TMPY-00516
Species: Human
Expression System: Baculovirus Insect Cells
METTL3 Protein, Human, Recombinant (His)
Cat.No: TMPH-01734
Species: Human
Expression System: E. coli
A2AR Protein-VLP, Human, Recombinant
Cat.No: TMPK-00861
Species: Human
Expression System: HEK293 Cells
HINT1 Protein, Rabbit, Recombinant (His & Myc)
Cat.No: TMPH-03205
Species: Rabbit
Expression System: HEK293 Cells
ADAR Protein, Human, Recombinant (His & SUMO)
Cat.No: TMPH-01248
Species: Human
Expression System: E. coli
ADAR Protein, Human, Recombinant (GST)
Cat.No: TMPH-01249
Species: Human
Expression System: E. coli
FHIT Protein, Mouse, Recombinant (His)
Cat.No: TMPH-02549
Species: Mouse
Expression System: E. coli
CKM Protein, Human, Recombinant (His)
Cat.No: TMPY-04762
Species: Human
Expression System: E. coli
TsaE Protein, E. coli, Recombinant
Cat.No: TMPH-00745
Species: E. coli
Expression System: E. coli
ACBD7 Protein, Human, Recombinant (His)
Cat.No: TMPY-03417
Species: Human
Expression System: E. coli
PDE1C Protein, Human, Recombinant (His & GST)
Cat.No: TMPY-02977
Species: Human
Expression System: Baculovirus Insect Cells
Cat. No. Product Name Target Signaling Pathways
TMID-0168 5'-Deoxy-5'-methylthioadenosine-d3

5'-Deoxy-5'-methylthioadenosine-d3 是 5'-Deoxy-5'-methylthioadenosine 的氘代化合物。5'-Deoxy-5'-methylthioadenosine 的 CAS 号为 2457-80-9。5'-Methylthioadenosine 是由 S-腺苷蛋氨酸在多胺合成过程中生成的核苷,通过抑制肿瘤细胞增殖、侵袭和诱导细胞凋亡来抑制肿瘤,同时控制肿瘤组织的炎症微环境。
T71327 Paraxanthine-d6

Paraxanthine-d6 is intended for use as an internal standard for the quantification of paraxanthine by GC- or LC-MS. Paraxanthine is an active metabolite of caffeine. It is formed via N3-demethylation of caffeine by the cytochrome P450 (CYP) isoform CYP1A2. Paraxanthine is an adenosine A1 and A2 receptor antagonist. In vivo, paraxanthine increases striatal cGMP and extracellular striatal dopamine levels and locomotor activity, as well as inhibits motor depression induced by the adenosine A1 agoni...
T71329 Theophylline-d6

Theophylline-d6 is intended for use as an internal standard for the quantification of theophylline by GC- or LC-MS. Theophylline is an inhibitor of phosphodiesterase. It is also an adenosine A1 and A2 receptor antagonist. Theophylline induces relaxation of isolated cat bronchial smooth muscle segments precontracted with acetylcholine. It inhibits ovalbumin-induced increases in bronchoalveolar lavage fluid (BALF) eosinophil infiltration in an ovalbumin-sensitized mouse model of allergic asthma. F...
TMID-0233 Salbutamol-d9

Salbutamol-d9 是 Salbutamol 的氘代化合物。Salbutamol 的 CAS 号为 18559-94-9。Salbutamol 是短效的 β2 肾上腺素受体激动剂,用于哮喘和慢性阻塞性肺疾病 (COPD) 引发的支气管痉挛的研究。
T71328 Theobromine-d6

Theobromine-d6 is intended for use as an internal standard for the quantification of theobromine by GC- or LC-MS. Theobromine is a methylxanthine alkaloid and derivative of caffeine that has been found in cocoa beans and has diverse biological activities. It is an adenosine A1 receptor antagonist. Theobromine increases AMPK phosphorylation and inhibits adipocyte differentiation, ERK and JNK phosphorylation, and IL-6 and TNF-α production in 3T3-L1 preadipocytes cultured in differentiation medium....
TMID-0167 6-Hydroxypurine-d4

6-Hydroxypurine-d4 是 6-Hydroxypurine 的氘代化合物。6-Hydroxypurine 的 CAS 号为 68-94-0。Hypoxanthine,也被称为 purine-6-ol 或 Hyp,属于嘌呤类有机化合物。Hypoxanthine 是一种天然存在的嘌呤衍生物,是腺苷代谢和核苷酸补救途径形成核酸的反应中间体。在正常情况下,Hypoxanthine 很容易转化为尿酸。Hypoxanthine 首先被氧化为黄嘌呤,黄嘌呤再被黄嘌呤氧化酶氧化为尿酸。
TMIH-0512 Salbutamol-d3

Salbutamol-d3 是 Salbutamol 的氘代化合物。Salbutamol 的 CAS 号为 18559-94-9。Salbutamol 是短效的 β2 肾上腺素受体激动剂,用于哮喘和慢性阻塞性肺疾病 (COPD) 引发的支气管痉挛的研究。

同位素标记化合物

5'-Deoxy-5'-methylthioadenosine-d3
Cat.No: TMID-0168
Synonym:
Target:
Paraxanthine-d6
Cat.No: T71327
Synonym:
Target:
Theophylline-d6
Cat.No: T71329
Synonym:
Target:
Salbutamol-d9
Cat.No: TMID-0233
Synonym:
Target:
Theobromine-d6
Cat.No: T71328
Synonym:
Target:
6-Hydroxypurine-d4
Cat.No: TMID-0167
Synonym:
Target:
Salbutamol-d3
Cat.No: TMIH-0512
Synonym:
Target:
TargetMol Loading
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