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Search Results for " activating "

Targets Recommended: Protease-activated Receptor

374

抑制剂 & 化合物

89

天然产物

4

化合物库

215

重组蛋白

6

同位素标记化合物

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Cat. No.	Product Name
L1300	PI3K/Akt/mTOR 化合物库		420 compounds
	420 种与PI3K/Akt/mTOR 相关的生物活性小分子化合物的特有集合，用于PI3K/Akt/mTOR 相关研究以及高通量、高内涵筛选；
L8600	泛素化化合物库		210 compounds
	210 种泛素化相关的小分子，用于高通量和高内涵筛选；
L8720	细胞焦亡化合物库		1066 compounds
	1066 种细胞焦亡相关的化合物，可以用于细胞焦亡相关研究。
L6750	活血化瘀中药单体库		580 compounds
	580种来源于常见活血化瘀中药的单体化合物，是药物开发、药理研究等领域的有效工具。

化合物库

PI3K/Akt/mTOR 化合物库

Cat.No: L1300

Compounds: 420

泛素化化合物库

Cat.No: L8600

Compounds: 210

细胞焦亡化合物库

Cat.No: L8720

Compounds: 1066

活血化瘀中药单体库

Cat.No: L6750

Compounds: 580

Cat. No.	Product Name	Target	Signaling Pathways
TP1046L	PAR-2 Activating Peptide acetate SLIGRL-NH2 acetate,PAR-2 Activating Peptide acetate(171436-38-7 free base),Protease-Activated Receptor-2 Activating Peptide acetate	Protease-activated Receptor	GPCR/G Protein
	PAR-2 Activating Peptide acetate (SLIGRL-NH2 acetate)(171436-38-7 free base) 是 Protease-Activated Receptor-2 (PAR-2) 的激动剂。
T2503	PAC-1 Procaspase activating compound 1	Apoptosis; Caspase; Autophagy	Apoptosis; Autophagy; Proteases/Proteasome
	PAC-1 (Procaspase activating compound 1) 是一种 procaspase-3激活剂，诱导癌细胞凋亡，EC50为 2.08 μM，可用于研究淋巴瘤、黑色素瘤、实体瘤、乳腺癌和胸癌等治疗的试验。
TP1046	SLIGRL-NH2 Protease-Activated Receptor-2 Activating Peptide	Protease-activated Receptor	GPCR/G Protein
	SLIGRL-NH2 (Protease-Activated Receptor-2 Activating Peptide) 为一种蛋白酶激活受体-2 (PAR-2) 激动剂，具有诱导非组胺能性瘙痒的功能。
TP2411	Sperm-activating peptide 1
	Sperm-activating peptide 1 is a bioactive chemical.
T81372	Proteasome-activating peptide 1
	Proteasome-activating peptide 1 是一种肽，其作用是提升胰凝乳蛋白酶样蛋白酶体（proteasome）的催化活性，有效增强体外及细胞培养环境下的蛋白质降解效率。此外，该肽能阻止肌萎缩侧索硬化症（Amyotrophic Lateral Sclerosis, ALS）细胞模型中蛋白质的过度聚集。
T76243	Proteasome-activating peptide 1 TFA
	Proteasome-activating peptide 1 TFA 是一种肽类蛋白酶体激活剂，能显著增强胰凝乳蛋白酶样蛋白酶体的催化活性，进而提升体外及培养环境中的蛋白质水解效率。此外，Proteasome-activating peptide 1 TFA 还能有效阻止肌萎缩侧索硬化症细胞模型内的蛋白质聚集现象。
T5374	NAcM-OPT	E1/E2/E3 Enzyme; NEDD8	Metabolism; Ubiquitination
	NAcM-OPT 是口服活性、有效的 cullin neddylation 1 抑制剂，可以抑制 DCN1-UBE2M 相互作用。
T80069	PACAP (6-27) (human, ovine, rat) Pituitary adenylate cyclase-activating peptide (6-27)
	PACAP (6-27) (human, ovine, rat) 是一种对PACAP受体具有拮抗作用的化合物，可以抑制犬肾上腺对外源性VIP的反应。此化合物在心血管疾病和神经系统疾病研究中展现出应用潜力。
T24136	Heclin	E1/E2/E3 Enzyme	Ubiquitination
	Heclin 是一种 HECT E3 泛素连接酶抑制剂，通过抑制 Smurf2、Nedd4 和 WWP1 起作用，IC50 值分别为 6.8、6.3 和 6.9 μM。
T75902	SLIGRL-NH2 TFA Protease-Activated Receptor-2 Activating Peptide TFA	Others	Others
	SLIGRL-NH2 TFA（Protease-Activated Receptor-2 Activating Peptide TFA）作为PAR-2（蛋白酶激活受体-2）的激动剂，具有高度特异性。
T3517	RO8994	Mdm2; E1/E2/E3 Enzyme; p53	Apoptosis; Ubiquitination
	RO8994是一种高效且特异性的螺吲哚酮小分子 MDM2 抑制剂，MTT 增殖试验和HTRF 结合试验的IC50 为 20 nM 和 5 nM。
T16102	ML-792	E1/E2/E3 Enzyme	Ubiquitination
	ML-792 是特异性的小泛素样修饰物活化酶抑制剂。ML-792选择性抑制SAE/SUMO1和SAE/SUMO2，IC50分别为 3 和 11 nM，对 NAE/NEDD8 和 UAE/ubiquitin 抑制作用微弱，IC50分别为 32 μM 和 >100 μM。
T5199	COH000	E1/E2/E3 Enzyme	Ubiquitination
	COH000 是不可逆的泛素样激活酶1 共价变构抑制剂，体外测得对 SUMO 化修饰的IC50=0.2 μM。
T12261	NSC232003	E1/E2/E3 Enzyme	Ubiquitination
	NSC232003 是高效的UHRF1抑制剂，能够抑制 DNA 甲基化，并破坏 DNMT1/UHRF1 相互作用。
T16699	PYZD-4409	Others; E1/E2/E3 Enzyme	Others; Ubiquitination
	PYZD-4409 是一种特异性 UBA1 抑制剂，IC50 为 20 μM。 PYZD-4409 在恶性细胞中诱导细胞死亡，并且对恶性细胞的细胞毒性优于对正常造血细胞的细胞毒性。
T7415	DKM 2-93	E1/E2/E3 Enzyme	Ubiquitination
	DKM 2-93是相对选择性 UBA5抑制剂，IC50=430 μM。
T16901	SMIP004	Apoptosis; Others; E1/E2/E3 Enzyme	Apoptosis; Others; Ubiquitination
	SMIP004 是一种 SKP2 E3 连接酶抑制剂。 SMIP004 是人前列腺癌细胞的癌细胞特异性凋亡诱导剂。
T2158	Nutlin-3 Nutlin3	E1/E2/E3 Enzyme	Ubiquitination
	Nutlin-3 是一种 MDM2 拮抗剂，抑制 MDM2-p53 相互作用，Ki 为 90 nM，并激活 p53。
TP1054	PACAP (1-38), human, ovine, rat TFA Pituitary Adenylate Cyclase Activating Polypeptide 38 (TFA)
	PACAP (1-38), a novel neuropeptide isolated from the bovine hypothalamus is more active than vasoactive intestinal peptide (VIP) in stimulating adenylate cyclase (EC50=7 nM). PACAP 1-38 (10-9 M) increased substance P (SP), gastrin releasing peptide (GRP),
T13349	WS-383	E1/E2/E3 Enzyme	Ubiquitination
	WS-383 是高效、选择性、可逆的DCN1-UBC12相互作用抑制剂，IC50为11 nM。它抑制 Cul3/1 的类泛素化修饰，引起 NRF2，p21和p27 的积累。
T11980	MD-224	Mdm2; E1/E2/E3 Enzyme; PROTACs	Apoptosis; PROTAC; Ubiquitination
	MD-224是一种基于蛋白水解靶向嵌合体（PROTAC）概念的高效、高效的MDM2降解剂，是一类新型抗癌剂。
T16888	SJ-172550	Mdm2; E1/E2/E3 Enzyme	Apoptosis; Ubiquitination
	SJ-172550 是 MDMX 的小分子抑制剂，EC50为5 μM。
T7379	2-D08	E1/E2/E3 Enzyme; TAM Receptor	Tyrosine Kinase/Adaptors; Ubiquitination
	2-D08是小泛素样修饰蛋白抑制剂。2-D08也能抑制 Axl，IC50=0.49 nM。
T8428	Subasumstat TAK-981	E1/E2/E3 Enzyme	Ubiquitination
	Subasumstat (TAK-981) 是SUMOylation 酶联反应的选择性抑制剂，具有潜在的免疫激活和抗肿瘤特性。
T6629	PYR-41 PYR41,PYR 41	Apoptosis; E1/E2/E3 Enzyme	Apoptosis; Ubiquitination
	PYR-41 是一种选择性，可透过细胞的泛素活化酶 E1抑制剂，IC50值小于10 μM。
T6149	YH239-EE	Apoptosis; E1/E2/E3 Enzyme	Apoptosis; Ubiquitination
	YH239-EE 是 YH239 的乙酯，是 p53-MDM2 拮抗剂和凋亡诱导剂。
T3653	MX69	Mdm2; E1/E2/E3 Enzyme; IAP	Apoptosis; Ubiquitination
	MX69 是用于抗癌研究的一种MDM2/XIAP 抑制剂。
T9236	WSB1 Degrader 1	Others; E1/E2/E3 Enzyme	Others; Ubiquitination
	WSB1 Degrader 1 是具有口服活性的 WSB1降解剂，具有抗癌活性。
T10703	Mezigdomide CC-92480	Apoptosis; E1/E2/E3 Enzyme; Molecular Glues	Apoptosis; PROTAC; Ubiquitination
	Mezigdomide (CC-92480) 是一种有效的、新型的、具有选择性的和具有活性的 cereblon E3 泛素连接酶调节剂 (CELMoD)，常以分子胶的方式发挥作用。Mezigdomide 具有抗骨髓瘤活性。
T13244	Ubiquitination-IN-1	Others	Others
	Ubiquitination-IN-1 是一种有效的泛素化和Cksl-Skp2蛋白互作抑制剂 (IC50=0.17 μM) 抑制剂，增加 p27 水平，可通过阻断肿瘤抑制因子的降解发挥作用。
T3317	SZL P1-41	Apoptosis; Others; E1/E2/E3 Enzyme	Apoptosis; Others; Ubiquitination
	SZL P1-41 是 Skp2 抑制剂，可以阻止 Skp2-Skp1 复合物的组装。它选择性地抑制 Skp2 SCF E3 连接酶活性，还在体内外抑制 Skp2 介导的 p27 和 Akt 泛素化。它通过触发细胞衰老和抑制糖酵解来抑制 Y 细胞和 Y 干细胞的存活，有抗肿瘤作用。
T7889	C25-140	Others; TNF; E1/E2/E3 Enzyme; NF-κB	Apoptosis; NF-κB; Others; Ubiquitination
	C25-140 是一种具有口服活性和一定选择性的 TRAF6-Ubc13相互作用抑制剂。它直接与 TRAF6 结合，阻断 TRAF6 和 Ubc13 的相互作用，降低 TRAF6 和 NF-κB 的活性，并与自身免疫对抗。
T8564	BC-1382	Others; E1/E2/E3 Enzyme	Others; Ubiquitination
	BC-1382 是E3泛素连接酶HECTD2抑制剂，能够特异性破坏 HECTD2/PIAS1 相互作用 (IC50≈ 5 nM)。BC-1382具有抗炎活性。
T23371	SMER3 SMER 3	Others; Ligand for E3 Ligase	Others; PROTAC
	SMER3 是选择性的 Skp1-Cullin-F-box (SCF)Met30泛素连接酶抑制剂。SMER 3 通过抑制 SCFMet30来增强 Rapamycin 的生长抑制作用。
T3549	Avadomide CC 122	Apoptosis; E1/E2/E3 Enzyme; Ligand for E3 Ligase	Apoptosis; PROTAC; Ubiquitination
	Avadomide (CC 122) 是口服有效的cereblon 调节剂，可以调节 cereblon E3 连接酶活性，诱导弥漫性大 B 细胞淋巴瘤细胞凋亡，具有抗肿瘤和免疫调节活性。
T4253	Skp2 Inhibitor C1 SKPin C1	Others; E1/E2/E3 Enzyme	Others; Ubiquitination
	Skp2 Inhibitor C1 (SKPin C1)(SKPin C1)是Skp2介导p27降解的特异性抑制剂。
T6332	Pevonedistat MLN4924	E1/E2/E3 Enzyme; NEDD8	Metabolism; Ubiquitination
	Pevonedistat (MLN4924) 是一种 NEDD8 活化酶 (NAE) 抑制剂 (IC50=4.7 nM)，具有有效性和选择性。Pevonedistat 可以用于骨髓增生异常综合症 (MDS)的治疗，也具有抗肿瘤活性。
T8844	Diflapolin	Others; FLAP; Epoxide Hydrolase	Immunology/Inflammation; Metabolism; Others
	Diflapolin 是高活性的双 5-脂氧合酶激活蛋白(FLAP)/可溶性环氧化物水解酶抑制剂，具有显著的抗炎作用和较高的靶向选择性。它抑制分离的 sEH 的活性，IC50为20 nM。它还抑制完整人单核细胞和中性粒细胞中 5-LOX 产物的形成，IC50分别为 30 和 170 nM。
T3110	PRT4165 NSC600157,PRT 4165	BMI-1; Others; E1/E2/E3 Enzyme	Cell Cycle/Checkpoint; DNA Damage/DNA Repair; Others; Ubiquitination
	PRT4165 (NSC600157) 是有效的 PRC1介导 H2A 泛素化的抑制剂。
T5555	Siremadlin NVP-HDM 201	E1/E2/E3 Enzyme	Ubiquitination
	Siremadlin (NVP-HDM 201) 是一种有效的、可口服的、高度特异性的 p53-MDM2 相互作用抑制剂。
TQ0127	Navtemadlin AMG232,CS-1300	Mdm2; E1/E2/E3 Enzyme	Apoptosis; Ubiquitination
	Navtemadlin (AMG232) 是一种有效的、选择性的、可口服的 p53-MDM2 相互作用抑制剂，IC50值为 0.6 nM。它以 0.045 nM 的 Kd 与 MDM2 结合。
T13090	TAS4464 hydrochloride	E1/E2/E3 Enzyme; NEDD8	Metabolism; Ubiquitination
	TAS4464 hydrochloride 是高效的、选择性的 NEDD8 活化酶 (NAE)抑制剂，其 IC50=0.955 nM。
T6254	Idasanutlin RG7388,Ro 5503781,依达奴林	Mdm2; E1/E2/E3 Enzyme	Apoptosis; Ubiquitination
	Idasanutlin (Ro 5503781) 是一种有效且特异性的 p53-MDM2 抑制剂，IC50值为 6 nM。
T6965	RG7112 RG-7112,RG 7112,RO5045337	Mdm2; E1/E2/E3 Enzyme	Apoptosis; Ubiquitination
	RG7112 (RO5045337) 是一种口服生物可利用的选择性 p53-MDM2 抑制剂。
T16974	TAK-243 MLN7243	Apoptosis; E1/E2/E3 Enzyme; NF-κB	Apoptosis; NF-κB; Ubiquitination
	TAK-243 (MLN7243) 是一种泛素激活酶 UAE 的抑制剂 (IC50=1 nM)，具有选择性。TAK-243 可阻断泛素结合，破坏单泛素信号传导以及整体蛋白质泛素化。TAK-243 具有抗肿瘤活性，可以促进细胞凋亡。
T9023	Atuliflapon AZD5718	FLAP	Immunology/Inflammation
	Atuliflapon (AZD5718) 是可口服的FLAP(5 -脂氧合酶激活蛋白)的抑制剂，IC50值为 2 nM，可用于冠状动脉疾病的研究。
T16087	Quiflapon 喹夫拉朋,MK-591	Apoptosis; FLAP	Apoptosis; Immunology/Inflammation
	Quiflapon (MK-591) 是一种选择性和特异性的FLAP 抑制剂，可诱导细胞凋亡。它也是口服白三烯生物合成抑制剂，在完整的人和诱导的大鼠多形核白细胞 PMNLs 中，其IC50值分别为 3.1 nM 和 6.1 nM。
TQ0231	NVP-CGM097 CGM097	Mdm2; E1/E2/E3 Enzyme	Apoptosis; Ubiquitination
	NVP-CGM097 (CGM097) 是一种选择性MDM2抑制剂，对hMDM2的IC50为 1.7 nM。
T1493	BH3I-1 BHI1	BCL; E1/E2/E3 Enzyme	Apoptosis; Ubiquitination
	BH3I-1 (BHI1) 是一种Bcl-2家族拮抗剂，作用于p53/mDM2，Kd 为 5.3 μM。它抑制BakBH3 肽与Bcl-xL 结合，Ki 为 2.6 μM。
TP1878	PACAP (1-38), human, ovine, rat Pituitary Adenylate Cyclase Activating Polypeptide 38,腺苷酸环化酶激活肽-38(抗原),PACAP 1-38	PACAP	GPCR/G Protein
	PACAP (1-38), human, ovine, rat (Pituitary Adenylate Cyclase Activating Polypeptide 38) 是含有 38 个氨基酸残基的神经肽。它能够结合 PACAP I 型受体(IC50:4 nM)、PACAP II 型受体 VIP1(IC50:2 nM)、PACAP II 型受体 VIP2(IC50:1 nM)。

化合物

PAR-2 Activating Peptide acetate

Cat.No: TP1046L

Synonym: SLIGRL-NH2 acetate,PAR-2 Activating Peptide acetate(171436-38-7 free base),Protease-Activated Receptor-2 Activating Peptide acetate

Target: Protease-activated Receptor

Cat.No: T2503

Synonym: Procaspase activating compound 1

Target: Apoptosis, Caspase, Autophagy

Cat.No: TP1046

Synonym: Protease-Activated Receptor-2 Activating Peptide

Target: Protease-activated Receptor

Sperm-activating peptide 1

Cat.No: TP2411

Proteasome-activating peptide 1

Cat.No: T81372

Proteasome-activating peptide 1 TFA

Cat.No: T76243

Cat.No: T5374

Target: E1/E2/E3 Enzyme, NEDD8

PACAP (6-27) (human, ovine, rat)

Cat.No: T80069

Synonym: Pituitary adenylate cyclase-activating peptide (6-27)

Cat.No: T24136

Target: E1/E2/E3 Enzyme

Cat.No: T75902

Synonym: Protease-Activated Receptor-2 Activating Peptide TFA

Target: Others

Cat.No: T3517

Target: Mdm2, E1/E2/E3 Enzyme, p53

Cat.No: T16102

Target: E1/E2/E3 Enzyme

Cat.No: T5199

Target: E1/E2/E3 Enzyme

Cat.No: T12261

Target: E1/E2/E3 Enzyme

Cat.No: T16699

Target: Others, E1/E2/E3 Enzyme

Cat.No: T7415

Target: E1/E2/E3 Enzyme

Cat.No: T16901

Target: Apoptosis, Others, E1/E2/E3 Enzyme

Cat.No: T2158

Synonym: Nutlin3

Target: E1/E2/E3 Enzyme

PACAP (1-38), human, ovine, rat TFA

Cat.No: TP1054

Synonym: Pituitary Adenylate Cyclase Activating Polypeptide 38 (TFA)

Cat.No: T13349

Target: E1/E2/E3 Enzyme

Cat.No: T11980

Target: Mdm2, E1/E2/E3 Enzyme, PROTACs

Cat.No: T16888

Target: Mdm2, E1/E2/E3 Enzyme

Cat.No: T7379

Target: E1/E2/E3 Enzyme, TAM Receptor

Cat.No: T8428

Synonym: TAK-981

Target: E1/E2/E3 Enzyme

Cat.No: T6629

Synonym: PYR41,PYR 41

Target: Apoptosis, E1/E2/E3 Enzyme

Cat.No: T6149

Target: Apoptosis, E1/E2/E3 Enzyme

Cat.No: T3653

Target: Mdm2, E1/E2/E3 Enzyme, IAP

WSB1 Degrader 1

Cat.No: T9236

Target: Others, E1/E2/E3 Enzyme

Cat.No: T10703

Synonym: CC-92480

Target: Apoptosis, E1/E2/E3 Enzyme, Molecular Glues

Ubiquitination-IN-1

Cat.No: T13244

Target: Others

Cat.No: T3317

Target: Apoptosis, Others, E1/E2/E3 Enzyme

Cat.No: T7889

Target: Others, TNF, E1/E2/E3 Enzyme, NF-κB

Cat.No: T8564

Target: Others, E1/E2/E3 Enzyme

Cat.No: T23371

Synonym: SMER 3

Target: Others, Ligand for E3 Ligase

Cat.No: T3549

Synonym: CC 122

Target: Apoptosis, E1/E2/E3 Enzyme, Ligand for E3 Ligase

Skp2 Inhibitor C1

Cat.No: T4253

Synonym: SKPin C1

Target: Others, E1/E2/E3 Enzyme

Cat.No: T6332

Synonym: MLN4924

Target: E1/E2/E3 Enzyme, NEDD8

Cat.No: T8844

Target: Others, FLAP, Epoxide Hydrolase

Cat.No: T3110

Synonym: NSC600157,PRT 4165

Target: BMI-1, Others, E1/E2/E3 Enzyme

Cat.No: T5555

Synonym: NVP-HDM 201

Target: E1/E2/E3 Enzyme

Cat.No: TQ0127

Synonym: AMG232,CS-1300

Target: Mdm2, E1/E2/E3 Enzyme

TAS4464 hydrochloride

Cat.No: T13090

Target: E1/E2/E3 Enzyme, NEDD8

Cat.No: T6254

Synonym: RG7388,Ro 5503781,依达奴林

Target: Mdm2, E1/E2/E3 Enzyme

Cat.No: T6965

Synonym: RG-7112,RG 7112,RO5045337

Target: Mdm2, E1/E2/E3 Enzyme

Cat.No: T16974

Synonym: MLN7243

Target: Apoptosis, E1/E2/E3 Enzyme, NF-κB

Cat.No: T9023

Synonym: AZD5718

Target: FLAP

Cat.No: T16087

Synonym: 喹夫拉朋,MK-591

Target: Apoptosis, FLAP

Cat.No: TQ0231

Synonym: CGM097

Target: Mdm2, E1/E2/E3 Enzyme

Cat.No: T1493

Synonym: BHI1

Target: BCL, E1/E2/E3 Enzyme

PACAP (1-38), human, ovine, rat

Cat.No: TP1878

Synonym: Pituitary Adenylate Cyclase Activating Polypeptide 38,腺苷酸环化酶激活肽-38(抗原),PACAP 1-38

Target: PACAP

Cat. No.	Product Name	Target	Signaling Pathways
T4S0181	Hinokiflavone 日本扁柏黄酮,扁柏双黄酮	MMP; BCL; E1/E2/E3 Enzyme	Apoptosis; Proteases/Proteasome; Ubiquitination
	Hinokiflavone 是pre-mRNA 剪接活性的新型调节剂，通过抑制剪接体装配来阻止pre-mRNA 底物的剪接，特别是阻止 B complex 的形成。它是SUMO protease 蛋白酶抑制剂，能够抑制前哨蛋白特异性蛋白酶 1 的活性。
T9352	hydrocotarnine	Others	Others
	hydrocotarnine 是 Cbl 的抑制剂。
T4036	Solasodine Solancarpidine,Purapuridine,澳洲茄铵,Solasodin	Apoptosis; Others; E1/E2/E3 Enzyme; Antifungal	Apoptosis; Microbiology/Virology; Others; Ubiquitination
	Solasodine (Purapuridine) 是存在于茄科植物中的一种类固醇生物碱。它具有神经保护、降压、抗真菌、抗癌、抗动脉粥样硬化、抗雄激素和抗炎活性。
T2947	Indole-3-carbinol 吲哚-3-甲醇,I3C,3-Indolemethanol,3-吲哚甲醇,Indole-3-Methanol	E1/E2/E3 Enzyme; NF-κB; Aryl Hydrocarbon Receptor; Endogenous Metabolite; p53	Apoptosis; Immunology/Inflammation; Metabolism; NF-κB; Ubiquitination
	Indole-3-carbinol (I3C) 是樟子松中的一种天然产物，是可口服的硫代葡萄糖苷葡糖苷酶裂解产物。它是芳烃受体 (AhR) 的激动剂，可抑制 NF-κB 和 IκBα 激酶活化。
T6S2123	Ginkgolic Acid Romanicardic acid,Ginkgolic acid I,Ginkgolic acid (15:1),银杏酸C15:1,银杏酸,Ginkgolic acid C15:1	Others; E1/E2/E3 Enzyme	Others; Ubiquitination
	Ginkgolic Acid (Romanicardic acid) 是一种天然化合物，在体外实验中抑制SUMOylation，IC50=3.0 μM。
T8288	14-Deoxyandrographolide 去氧穿心莲内酯,14-去氧穿心莲内酯	Apoptosis; Others	Apoptosis; Others
	14-Deoxyandrographolide 是穿心莲中的一种天然产物，是一种钙通道阻断剂，具有保肝功效。它通过诱导 TNFRSF1A 的释放，使肝细胞对 TNF-α 介导的凋亡脱敏。
TN4222	Homoeriodictyol 7-O-β-D-glucoside 高圣草素-7-O-Β-D-葡萄糖苷,Homoeriodictyol 7-O-glucoside	Others; Platelet aggregation	Others
	Homoeriodictyol 7-O-β-D-glucoside (Homoeriodictyol 7-O-glucoside) 是 Viscum coloratum(Kom.)Nakai 的天然产物。Homoeriodictyol 7-O-β-D-glucoside 是血小板活化因子 (PAF) 的拮抗剂。
T4950	1,2-Dipalmitoyl-sn-glycerol 1,2-双棕榈酸甘油酯,(S)-1,2-Dipalmitin	Endogenous Metabolite; PKC	Chromatin/Epigenetic; Cytoskeletal Signaling; Metabolism
	1,2-Dipalmitoyl-sn-glycerol ((S)-1,2-Dipalmitin) 是内源性代谢产物的一种。
T0800	Danthron Dantron,1,8-Dihydroxyanthraquinone,1,8-二羟基蒽醌,丹蒽醌,Chrysazin,Antrapurol	Virus Protease; Antibacterial; AMPK; Autophagy	Autophagy; Chromatin/Epigenetic; Microbiology/Virology; PI3K/Akt/mTOR signaling
	Danthron (Antrapurol) 是一种从中药 rhubarb 中提取的天然产物，可通过激活 AMPK 来调节葡萄糖和脂质代谢。
T2839	Orsellinic acid	Apoptosis; Others	Apoptosis; Others
	Orsellinic acid是一种利用Lecanoric acidy 用醇处理后得到的化合物,，抑制血小板活化因子（PAF）介导的神经元凋亡。
T0129	Sanguinarine chloride Pseudochelerythrine chloride,血根碱,氯化血根碱,Sanguinarium chloride	Apoptosis; EGFR; VEGFR; Antibacterial; Parasite; Autophagy	Angiogenesis; Apoptosis; Autophagy; JAK/STAT signaling; Microbiology/Virology; Tyrosine Kinase/Adaptors
	Sanguinarine chloride (Pseudochelerythrine chloride) 是一种来源于 Sanguinaria Canadensis 的生物碱，通过激活活性氧的产生，诱导细胞凋亡。
T3896	Shanzhiside methyl ester 三栀子甙甲酯,山芝皂苷甲酯	Glucagon Receptor	GPCR/G Protein
	Shanzhiside methyl ester 是一种小分子胰高血糖素样肽 1 受体激动剂，分离自轮状乳杆菌，能够诱导抗异常性痛觉耐受。
TN4114	Gardenin A	ERK; LDL; MAPK; PKA; PKC	Chromatin/Epigenetic; Cytoskeletal Signaling; MAPK; Metabolism; Tyrosine Kinase/Adaptors
	Gardenin A 通过激活 MAPK/ERK、PKC 和 PKA 表现出神经营养作用。 Gardenin A 具有抗抑郁、抗惊厥和抗焦虑作用。
T5281	Skatole 粪臭素,Scatole,3-Methylindole,3-Methylindole,3-甲基吲哚,3-Methyl-1H-indole,beta-Methylindole	AhR; p38 MAPK; Aryl Hydrocarbon Receptor; Endogenous Metabolite; Antibacterial; Autophagy; Antifungal	Autophagy; Immunology/Inflammation; MAPK; Metabolism; Microbiology/Virology
	Skatole (3-Methyl-1H-indole) 是由肠道菌群产生的，通过激活芳基烃受体和 p38调节肠上皮细胞功能。
TN2346	Mogrol	ERK; AMPK; STAT	Chromatin/Epigenetic; JAK/STAT signaling; MAPK; PI3K/Akt/mTOR signaling; Stem Cells
	Mogrol 是罗汉果中的一种天然产物，通过抑制 ERK1/2 和 STAT3 通路，减少 CREB 激活和激活 AMPK 信号传导发挥作用。
T1399	Sucralose Trichlorosucrose,三氯蔗糖,E955	Others; Endogenous Metabolite	Metabolism; Others
	Sucralose 是一种无营养的人工甜味剂 (sweetener) 和代糖，它能够激活保守神经的禁食响应，从而刺激啮齿动物产生食欲。
T2A2497	L-Glutamic acid 谷氨酸,(S)-Glutamic acid,glutamic acid,(+)-L-Glutamic acid,Aciglut,L-谷氨酸,glutacid,Glutaminol	Apoptosis; Ferroptosis; Endogenous Metabolite; iGluR	Apoptosis; Membrane transporter/Ion channel; Metabolism; Neuroscience
	L-Glutamic acid (Glutaminol) 作为一种兴奋性氨基酸神经递质，为谷氨酸盐受体所有亚型的激动剂，对多巴胺从神经末梢释放的过程有激动作用。
T5S2178	Fargesin 辛夷脂素,(+/-)-Fargesin	Adrenergic Receptor	GPCR/G Protein; Neuroscience
	Fargesin ((+/-)-Fargesin) 是一种活性新木脂素，从木兰植物中分离得到，具有抗高血压和抗炎活性。
T3S0335	Soyasaponin Bb Soyasaponin I,大豆皂苷Bb	NF-κB; Caspase	Apoptosis; NF-κB; Proteases/Proteasome
	Soyasaponin Bb (Soyasaponin I) 是一种分离自菜豆科中的大豆皂苷，可用作醛糖还原酶差异抑制剂。
T3916	Ginsenoside F2 人参皂苷F2	Apoptosis; Endogenous Metabolite; Autophagy	Apoptosis; Autophagy; Metabolism
	Ginsenoside F2 是 Ginsenoside Rb1 的代谢物，通过激活内在的凋亡途径和线粒体功能障碍来诱导乳腺的凋亡，对乳腺癌干细胞具有抗增殖活性。
TN1461	(-)-Butin Butin,漆黄素 ( 紫铆素)	Akt; PI3K; Nrf2	Cytoskeletal Signaling; Immunology/Inflammation; PI3K/Akt/mTOR signaling
	(-)-Butin (Butin) 是 Butin 的 S 对映体。其中 Butin 是一种分离自黄檀的心材中的生物活性黄酮类化合物，具有显著的抗血小板、抗氧化、抗炎作用。
T13818	Phytohemagglutinin PHA-M,植物血球凝集素,PHA,植物血凝素	Apoptosis	Apoptosis
	Phytohemagglutinin (PHA-M) 是一种普通豆菜豆的主要种子凝集素，聚集在子叶的薄壁细胞中。它是一种 T 细胞激活剂，能够刺激人单核白细胞，可诱导 ChAT mRNA 表达，增强 ACh 合成。
TN4379	Kansuinine A	IL Receptor; STAT; Interleukin	Immunology/Inflammation; JAK/STAT signaling; Stem Cells
	Kansuinine A 对IL-6 诱导的 Stat3激活有作用。Kansuinine A 显示出抗病毒和抗肿瘤活性。
T0627	β-Alanine beta-Alanine,beta-氨基丙酸,3-Aminopropanoic acid,2-Carboxyethylamine,β-丙氨酸	GABA Receptor; Endogenous Metabolite	Membrane transporter/Ion channel; Metabolism; Neuroscience
	β-Alanine (3-Aminopropanoic acid) 是一种天然存在的β-氨基酸，在体内由二氢尿嘧啶和肌肽降解形成，它作为神经递质可激活甘氨酸和GABA受体。
T5764	Alliin 蒜氨酸,(S)-3-(Allylsulphinyl)-L-alanine	NF-κB; PPAR	DNA Damage/DNA Repair; Metabolism; NF-κB
	Alliin ((S)-3-(Allylsulphinyl)-L-alanine) 是一种从大蒜中提取的亚砜化合物，具有口服活性，表现出降血糖、抗氧化和抗炎特性。
T3665	Tectoridin 射干苷,Shekanin	Estrogen Receptor/ERR; Reductase	Endocrinology/Hormones; Metabolism
	Tectoridin (Shekanin) 是分离自 Maackia amurensis 中的异黄酮，是一种植物雌激素，能够激活雌激素和甲状腺激素受体。它通过 ER 依赖性基因组途径和 GPR30 依赖性非基因组途径发挥雌激素作用。
TN7036	N-(3-Methoxybenzyl)-(9Z,12Z,15Z)-octadecatrienamide (9Z,12Z,15Z)-N-[(3-Methoxyphenyl)methyl]-9,12,15-octadecatrienamide,间-甲氧基苄基-亚麻酰胺,Macamide Impurity 14	Wnt/beta-catenin	Cytoskeletal Signaling; Stem Cells
	N-(3-Methoxybenzyl)-(9Z,12Z,15Z)-octadecatrienamide (Macamide Impurity 14) 是一种从玛卡中分离得到的玛卡酰胺。它能够激活典型的Wnt/β‐catenin 信号通路，诱导间充质干细胞成骨分化和随后的骨形成，可用于研究骨质疏松症。
T50050	2,3-dihydroxy-3-methylbutanoic acid	Others	Others
	2,3-dihydroxy-3-methylbutanoic acid 是支链氨基酸亮氨酸的天然代谢产物。它通过激活mTOR 信号通路发挥作用，促进新肌肉蛋白的合成，减少现有蛋白质的分解，从而增加肌肉质量，改善运动后的恢复。
T2978	Mogroside V	AMPK	Chromatin/Epigenetic; PI3K/Akt/mTOR signaling
	Mogroside V 是三萜糖苷，是非糖类甜味剂，甜度比蔗糖甜高300倍。它具有抗氧化，抗糖尿病和抗癌作用。
T3867	Alpinetin 山姜素,(-)-alpinetin	BCL; PPAR	Apoptosis; DNA Damage/DNA Repair; Metabolism
	Alpinetin ((-)-alpinetin) 是从草豆蔻中分离得到的一种黄酮类天然产物，能够活化PPAR-γ，具有抗炎、抗菌活性。它通过抑制增殖、调节 Bcl-2 家族和 XIAP 表达、释放细胞色素 c 和激活 caspase 具有很强的抗肝癌和胰腺癌细胞作用。
TN2322	Yangambin	Calcium Channel; PAFR	GPCR/G Protein; Membrane transporter/Ion channel; Metabolism
	Yangambin 是从诸如番荔枝科植物中分离出来的呋喃木脂素，是选择性PAF 受体拮抗剂，通过调控Ca2+通道抑制 Ca2+流入，导致 [Ca2+]i 在血管平滑肌细胞和随后的外周血管舒张中减少，具有降压作用。
T4S1335	Daphnoretin Dephnoretin,西瑞香素,Thymelol	Influenza Virus; Caspase; PKC	Apoptosis; Chromatin/Epigenetic; Cytoskeletal Signaling; Microbiology/Virology; Proteases/Proteasome
	Daphnoretin (Thymelol) 是从了哥王中提取得到的一种天然产物，具有抗癌和抗病毒活性。它通过在 G2/M 期连续阻断细胞并激活 caspase-3 通路导致 HOS 细胞死亡。
T2S2173	(E)-Naringenin chalcone Isosalipurpol,柚皮苷查尔酮,Chalconaringenin,trans-2'4'6'4-tetrahydroxychalcone,柚皮素查耳酮	Others	Others
	Naringenin chalcone (Isosalipurpol) 是一种黄酮醇生物合成的中间体，在查耳酮异构酶的作用下，自发代谢成柚皮素。它具有抗炎和抗过敏活性。
TN2080	Pinoresinol 松脂酚，松脂素,(+)-Pinoresinol	Apoptosis; NF-κB; CDK; p53	Apoptosis; Cell Cycle/Checkpoint; NF-κB
	Pinoresinol ((+)-Pinoresinol) 是一种植物来源的木质素，具有抗炎、保肝和杀真菌活性。它导致 CDK 抑制剂 p21(WAF1/Cip1) 在 mRNA 和蛋白质水平上调，抑制 NF-kappaB 和激活蛋白 1 。
T3923	Calycosin Cyclosin,3'-Hydroxyformononetin,异黄酮,毛异黄酮	Apoptosis; Tyrosinase	Apoptosis; Proteases/Proteasome
	Calycosin (Cyclosin) 是一抗氧化和抗炎症活性天然产物。
T5S2358	Dehydrocorydaline Dehydrocorydalin,脱氢紫堇碱,13-Methylpalmatine	BCL; PARP; p38 MAPK; Caspase; Parasite; Autophagy	Apoptosis; Autophagy; Chromatin/Epigenetic; DNA Damage/DNA Repair; MAPK; Microbiology/Virology; Proteases/Proteasome
	Dehydrocorydaline (13-Methylpalmatine) 是一种生物碱。它调节Bax，Bcl-2蛋白表达，激活caspase-7，caspase-8，并使PARP 失活。它能增强p38 MAPK 活化，具有抗炎、抗癌等功效。它具有强大的抗疟疾作用，并具低细胞毒性。
T5S1805	5,7-Dihydroxychromone 5,7-Dihydroxy-4H-Chromen-4-One,5,7-二羟基色酮,5,7-二羟基色原酮	Others; Virus Protease; PARP; Caspase; Nrf2	Apoptosis; Chromatin/Epigenetic; DNA Damage/DNA Repair; Immunology/Inflammation; Microbiology/Virology; Others; Proteases/Proteasome
	5,7-Dihydroxychromone (5,7-Dihydroxy-4H-Chromen-4-One) 是一种Cudrania tricuspidata 的提取物，通过激活 Nrf2/ARE 信号对 6-OHDA 诱导的氧化应激和细胞凋亡发挥神经保护作用。它抑制 6-OHDA 诱导的 SH-SY5Y 细胞中活化的caspase-3，caspase-9以及切割的PARP 表达。
T2S2264	Linalool Linalol,(±)-Linalool,Phantol,沉香醇	Apoptosis; IL Receptor; TNF; Endogenous Metabolite; iGluR	Apoptosis; Immunology/Inflammation; Membrane transporter/Ion channel; Metabolism; Neuroscience
	Linalool (Linalol) 是存在芫荽等植物中的单萜类天然产物，是竞争性NMDA 受体拮抗剂，具有抗肿瘤和抗心脏毒性的作用。它通过激活 Nrf2 诱导抗氧化防御和通过抑制 NF-κB 减少炎症反应来保护其免受 LPS/GalN 诱导的肝损伤，具有镇痛、抗菌和抗炎的特性。
TN5171	Tricetin	Apoptosis; Others; Nrf2	Apoptosis; Immunology/Inflammation; Others
	Tricetin 是一种从石榴中分离出的类黄酮。Tricetin 是 Keap1-Nrf2 蛋白相互作用（PPI）的强效竞争性抑制剂，通过激活 Nrf2/HO-1 信号通路和阻止线粒体依赖性细胞凋亡通路，保护帕金森病患免受 6-OHDA 诱导的神经毒性的影响。Tricetin 通过 Akt/GSK-1β途径抑制鼻咽癌的迁移和指示性蛋白酶早老素-1（PS-1）表达。Tricetin 抑制由Egr-1介导的氧化LDL 诱导的内皮炎症，保护大鼠软骨细胞免受IL-1β诱导的炎症和细胞凋亡。
T7044	Norepinephrine 去甲肾上腺素,Levophed,Levonoradrenaline,Aktamin,Nor-Epirenan,Levonor,Arterenol	MMP; Endogenous Metabolite; Adrenergic Receptor; Autophagy	Autophagy; GPCR/G Protein; Metabolism; Neuroscience; Proteases/Proteasome
	Norepinephrine (Levophed) 属于生物碱类天然产物，是一种神经递质，一种肾上腺素能受体 (AR) 的激动剂，对 α1、α2 和 β1 AR 具有激活活性。Norepinephrine 被用作抗休克的血管活性剂。
T2988	(-)-Epigallocatechin Gallate Epigallocatechol Gallate,(-)-表没食子儿茶素没食子酸酯,EGCG	Ferroptosis; Reactive Oxygen Species; HIV Protease; Mitochondrial Metabolism; Endogenous Metabolite; Autophagy	Apoptosis; Autophagy; Immunology/Inflammation; Metabolism; Microbiology/Virology; NF-κB; Proteases/Proteasome
	(-)-Epigallocatechin Gallate (EGCG) 属于茶类黄酮天然产物，可抑制 EGFR 信号传导，抑制 GLUD 1/2。(-)-Epigallocatechin Gallate 具有抗氧化、抗炎和抗肿瘤活性。(-)-Epigallocatechin Gallate 可以通过激活细胞色素 c 氧化酶来诱导氧化磷酸化。
T25983	Prehispanolone LC 5504,LC5504,LC-5504
	Prehispanolone is a platelet activating factor antagonist from Chinese medicinal herb Leonurus heterophyllus.
T13559	Astragaloside VI	EGFR	Angiogenesis; JAK/STAT signaling; Tyrosine Kinase/Adaptors
	Astragaloside VI could improve wound healing by activating the EGFR/ERK signaling pathway.
TN3520	Bisdethiobis(methylthio)gliotoxin	PAFR	GPCR/G Protein
	Bisdethiobis(methylthio)gliotoxin is a platelet activating factor (PAF) antagonist.
TN5045	Spiradine F	PAFR	GPCR/G Protein
	Spiradine F can significantly inhibit platelet-activating factor(PAF)-induced platelet aggregation in a concentration-dependent manner.
TN4821	Pregomisin	PAFR	GPCR/G Protein
	Pregomisin shows platelet-activating factor (PAF) antagonistic activity and the IC 50 value is 4.8x10(-5) M.
T28021	meso-Dihydroguaiaretic acid
	meso-Dihydroguaiaretic acid is an LXR-α antagonist, it inhibits hepatic lipid accumulation by activating AMP-activated protein kinase in human HepG2 cells.
TN1654	Futoquinol	Others; ROS; PAFR	GPCR/G Protein; Immunology/Inflammation; Others
	Futoquinol is an anti-platelet activating factor principle from the stem part of Piper futokadsura (Piperaceae), the Chinese drug haifengteng.
TN4367	Kadsurin A	PAFR	GPCR/G Protein
	Kadsurin A 具有抗血小板活化因子活性。
TL0014	Pinusolide	ERK; p38 MAPK; Calcium Channel; Lipoxygenase; PAFR; Caspase; JNK; AMPK	Apoptosis; Chromatin/Epigenetic; GPCR/G Protein; MAPK; Membrane transporter/Ion channel; Metabolism; PI3K/Akt/mTOR signaling; Proteases/Proteasome
	Pinusolide is a platelet activating factor ( PAF) antagonist, it may prove of therapeutic value in the treatment of hypotension, it has antileukemic potential, and could be used to treat neurodegenerative diseases. Pinusolide attenuates blockade of insulin signaling by enhancing IRS-1 tyrosine phosphorylation by the activating the AMPK pathway, indicates the targeting of AMPK represents a new therapeutic strategy for hyperglycemia-induced insulin resistance and type 2 diabetes.
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天然产物

Cat.No: T4S0181

Synonym: 日本扁柏黄酮,扁柏双黄酮

Target: MMP, BCL, E1/E2/E3 Enzyme

Cat.No: T9352

Target: Others

Cat.No: T4036

Synonym: Solancarpidine,Purapuridine,澳洲茄铵,Solasodin

Target: Apoptosis, Others, E1/E2/E3 Enzyme, Antifungal

Indole-3-carbinol

Cat.No: T2947

Synonym: 吲哚-3-甲醇,I3C,3-Indolemethanol,3-吲哚甲醇,Indole-3-Methanol

Target: E1/E2/E3 Enzyme, NF-κB, Aryl Hydrocarbon Receptor, Endogenous Metabolite, p53

Cat.No: T6S2123

Synonym: Romanicardic acid,Ginkgolic acid I,Ginkgolic acid (15:1),银杏酸C15:1,银杏酸,Ginkgolic acid C15:1

Target: Others, E1/E2/E3 Enzyme

14-Deoxyandrographolide

Cat.No: T8288

Synonym: 去氧穿心莲内酯,14-去氧穿心莲内酯

Target: Apoptosis, Others

Homoeriodictyol 7-O-β-D-glucoside

Cat.No: TN4222

Synonym: 高圣草素-7-O-Β-D-葡萄糖苷,Homoeriodictyol 7-O-glucoside

Target: Others, Platelet aggregation

1,2-Dipalmitoyl-sn-glycerol

Cat.No: T4950

Synonym: 1,2-双棕榈酸甘油酯,(S)-1,2-Dipalmitin

Target: Endogenous Metabolite, PKC

Cat.No: T0800

Synonym: Dantron,1,8-Dihydroxyanthraquinone,1,8-二羟基蒽醌,丹蒽醌,Chrysazin,Antrapurol

Target: Virus Protease, Antibacterial, AMPK, Autophagy

Orsellinic acid

Cat.No: T2839

Target: Apoptosis, Others

Sanguinarine chloride

Cat.No: T0129

Synonym: Pseudochelerythrine chloride,血根碱,氯化血根碱,Sanguinarium chloride

Target: Apoptosis, EGFR, VEGFR, Antibacterial, Parasite, Autophagy

Shanzhiside methyl ester

Cat.No: T3896

Synonym: 三栀子甙甲酯,山芝皂苷甲酯

Target: Glucagon Receptor

Cat.No: TN4114

Target: ERK, LDL, MAPK, PKA, PKC

Cat.No: T5281

Synonym: 粪臭素,Scatole,3-Methylindole,3-Methylindole,3-甲基吲哚,3-Methyl-1H-indole,beta-Methylindole

Target: AhR, p38 MAPK, Aryl Hydrocarbon Receptor, Endogenous Metabolite, Antibacterial, Autophagy, Antifungal

Cat.No: TN2346

Target: ERK, AMPK, STAT

Cat.No: T1399

Synonym: Trichlorosucrose,三氯蔗糖,E955

Target: Others, Endogenous Metabolite

L-Glutamic acid

Cat.No: T2A2497

Synonym: 谷氨酸,(S)-Glutamic acid,glutamic acid,(+)-L-Glutamic acid,Aciglut,L-谷氨酸,glutacid,Glutaminol

Target: Apoptosis, Ferroptosis, Endogenous Metabolite, iGluR

Cat.No: T5S2178

Synonym: 辛夷脂素,(+/-)-Fargesin

Target: Adrenergic Receptor

Cat.No: T3S0335

Synonym: Soyasaponin I,大豆皂苷Bb

Target: NF-κB, Caspase

Cat.No: T3916

Synonym: 人参皂苷F2

Target: Apoptosis, Endogenous Metabolite, Autophagy

Cat.No: TN1461

Synonym: Butin,漆黄素 ( 紫铆素)

Target: Akt, PI3K, Nrf2

Phytohemagglutinin

Cat.No: T13818

Synonym: PHA-M,植物血球凝集素,PHA,植物血凝素

Target: Apoptosis

Cat.No: TN4379

Target: IL Receptor, STAT, Interleukin

Cat.No: T0627

Synonym: beta-Alanine,beta-氨基丙酸,3-Aminopropanoic acid,2-Carboxyethylamine,β-丙氨酸

Target: GABA Receptor, Endogenous Metabolite

Cat.No: T5764

Synonym: 蒜氨酸,(S)-3-(Allylsulphinyl)-L-alanine

Target: NF-κB, PPAR

Cat.No: T3665

Synonym: 射干苷,Shekanin

Target: Estrogen Receptor/ERR, Reductase

N-(3-Methoxybenzyl)-(9Z,12Z,15Z)-octadecatrienamide

Cat.No: TN7036

Synonym: (9Z,12Z,15Z)-N-[(3-Methoxyphenyl)methyl]-9,12,15-octadecatrienamide,间-甲氧基苄基-亚麻酰胺,Macamide Impurity 14

Target: Wnt/beta-catenin

2,3-dihydroxy-3-methylbutanoic acid

Cat.No: T50050

Target: Others

Cat.No: T2978

Target: AMPK

Cat.No: T3867

Synonym: 山姜素,(-)-alpinetin

Target: BCL, PPAR

Cat.No: TN2322

Target: Calcium Channel, PAFR

Cat.No: T4S1335

Synonym: Dephnoretin,西瑞香素,Thymelol

Target: Influenza Virus, Caspase, PKC

(E)-Naringenin chalcone

Cat.No: T2S2173

Synonym: Isosalipurpol,柚皮苷查尔酮,Chalconaringenin,trans-2'4'6'4-tetrahydroxychalcone,柚皮素查耳酮

Target: Others

Cat.No: TN2080

Synonym: 松脂酚，松脂素,(+)-Pinoresinol

Target: Apoptosis, NF-κB, CDK, p53

Cat.No: T3923

Synonym: Cyclosin,3'-Hydroxyformononetin,异黄酮,毛异黄酮

Target: Apoptosis, Tyrosinase

Dehydrocorydaline

Cat.No: T5S2358

Synonym: Dehydrocorydalin,脱氢紫堇碱,13-Methylpalmatine

Target: BCL, PARP, p38 MAPK, Caspase, Parasite, Autophagy

5,7-Dihydroxychromone

Cat.No: T5S1805

Synonym: 5,7-Dihydroxy-4H-Chromen-4-One,5,7-二羟基色酮,5,7-二羟基色原酮

Target: Others, Virus Protease, PARP, Caspase, Nrf2

Cat.No: T2S2264

Synonym: Linalol,(±)-Linalool,Phantol,沉香醇

Target: Apoptosis, IL Receptor, TNF, Endogenous Metabolite, iGluR

Cat.No: TN5171

Target: Apoptosis, Others, Nrf2

Cat.No: T7044

Synonym: 去甲肾上腺素,Levophed,Levonoradrenaline,Aktamin,Nor-Epirenan,Levonor,Arterenol

Target: MMP, Endogenous Metabolite, Adrenergic Receptor, Autophagy

(-)-Epigallocatechin Gallate

Cat.No: T2988

Synonym: Epigallocatechol Gallate,(-)-表没食子儿茶素没食子酸酯,EGCG

Target: Ferroptosis, Reactive Oxygen Species, HIV Protease, Mitochondrial Metabolism, Endogenous Metabolite, Autophagy

Cat.No: T25983

Synonym: LC 5504,LC5504,LC-5504

Astragaloside VI

Cat.No: T13559

Target: EGFR

Bisdethiobis(methylthio)gliotoxin

Cat.No: TN3520

Target: PAFR

Cat.No: TN5045

Target: PAFR

Cat.No: TN4821

Target: PAFR

meso-Dihydroguaiaretic acid

Cat.No: T28021

Cat.No: TN1654

Target: Others, ROS, PAFR

Cat.No: TN4367

Target: PAFR

Cat.No: TL0014

Target: ERK, p38 MAPK, Calcium Channel, Lipoxygenase, PAFR, Caspase, JNK, AMPK

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Species：

Expression System：

Tag：

Cat. No.	Product Name	Species	Expression System
TMPY-03441	SAE1 Protein, Human, Recombinant SUA1,SUMO1 activating enzyme subunit 1,HSPC140,UBLE...	Human	Baculovirus Insect Cells
	SAE1 Protein, Human, Recombinant is expressed in Baculovirus insect cells. The predicted molecular weight is 38.6 kDa and the accession number is Q9UBE0.
TMPY-02840	Ubiquitin Activating Enzyme E1/UBA1 Protein, Human, Recombinant (His & GST) UBE1,ubiquitin-like modifier activating enzyme 1,UB...	Human	Baculovirus Insect Cells
	UBE1, also known as UBA1, belongs to the ubiquitin-activating E1 family. UBE1 gene complements an X-linked mouse temperature-sensitive defect in DNA synthesis, and thus may function in DNA repair. It is part of a gene cluster on chromosome Xp11.23. UBE1 catalyzes the first step in ubiquitin conjugation to mark cellular proteins for degradation. It also catalyzes the first step in ubiquitin conjugation to mark cellular proteins for degradation by first adenylating its C-terminal glycine residue w...
TMPJ-01011	FGF-9 Protein, Mouse, Recombinant (His) heparin-binding growth factor-9,GAF,HBGF-9,Glia-activati...	Mouse	E. coli
	Fibroblast growth factor-9 (FGF-9) is an approximately 26 kDa secreted glycoprotein of the FGF family. Secreted mouse FGF-9 lacks the N-terminal 1-3 aa and shares >98% sequence identity with rat, human, equine, porcine and bovine FGF-9. FGF-9 plays an important role in the regulation of embryonic development, cell proliferation, cell differentiation and cell migration. In the mouse embryo the location and timing of FGF-9 expression affects development of the skeleton, cerebellum, lungs, heart, v...
TMPJ-00090	FGF-9 Protein, Human, Recombinant Fibroblast Growth Factor 9,Heparin-Binding Growth Factor 9,F...	Human	E. coli
	Fibroblast Growth Factor 9 (FGF-9) belongs to the Fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. FGF-9 plays an important role in the regulation of embryonic development, cell proliferation, cell differentiation and cell migration. In addition, FGF-9 may have a role in glial c...
TMPJ-01324	UBA5 Protein, Human, Recombinant (His) Ubiquitin-like modifier-activating enzyme 5,UBE1DC1...	Human	E. coli
	UBA5 is a member of the ubiquitin-activating E1 family and UBA5 subfamily. Ubiquitin and ubiquitin-like proteins are recognized as covalently conjugated to various cellular substrates by a three-step enzymatic pathway. The ubiquitin-activating enzyme (E1) has a vital role in the first step of ubiquitination pathway to activate ubiquitin or ubiquitin-like proteins. UBA5 activates ubiquitin-fold modifier 1, a ubiquitin-like post-translational modifier protein, via the formation of a high-energy th...
TMPJ-01391	BAFF/TNFSF13B Protein, Mouse, Recombinant (mFc) TALL-1,Dendritic cell-derived TNF-like molecule,BLyS,Tumor n...	Mouse	HEK293 Cells
	BAFF/TNFSF13B Protein, Mouse, Recombinant (mFc) is expressed in HEK293 mammalian cells with N-mFc tag. The predicted molecular weight is 45-60 KDa and the accession number is Q9WU72.
TMPY-01481	FLAP Protein, Human, Recombinant (His) FLAP,arachidonate 5-lipoxygenase-activating protein	Human	Baculovirus Insect Cells
	Arachidonate 5-Lipoxygenase-Activating Protein (ALOX5AP), also known as FLAP, belongs to the MAPEG family. ALOX5AP/FLAP is an essential partner of 5-LO for this process. The FLAP (ALOX5AP) gene has been linked to risk for myocardial infarction, stroke and restenosis, reigniting pharmaceutical interest in this target. It had been found that ALOX5AP/FLAP is a key enzyme in leukotriene formation, in both human pulmonary microvascular endothelial cells and a transformed human brain endothelial cell ...
TMPH-01997	SYNGAP1 Protein, Human, Recombinant (His) SYNGAP1,Neuronal RasGAP,Synaptic Ras GTPase-activating	Human	E. coli
	SYNGAP1 Protein, Human, Recombinant (His) is expressed in E. coli.
TMPH-02828	PLAA Protein, Mouse, Recombinant (His & Myc) Plaa,Phospholipase A-2-activating protein	Mouse	Baculovirus Insect Cells
	PLAA Protein, Mouse, Recombinant (His & Myc) is expressed in Baculovirus insect cells with N-10xHis and C-Myc tag. The predicted molecular weight is 13.6 kDa and the accession number is P27612.
TMPJ-00611	SFP Protein, B.subtilis, Recombinant (His) Surfactin synthase-activating enzyme,sfp,lpa-8,4'-p...	Bacillus subtilis	E. coli
	The Bacillus subtilis enzyme Sfp, required for production of the lipoheptapeptide antibiotic surfactin, posttranslationally phosphopantetheinylates a serine residue in each of the seven peptidyl carrier protein domains of the first three subunits (SrfABC) of surfactin synthetase to yield docking sites for amino acid loading and peptide bond formation.
TMPY-03062	SAE1 Protein, Human, Recombinant (His & GST) UBLE1A,SUMO1 activating enzyme subunit 1,AOS1,HSPC1...	Human	Baculovirus Insect Cells
	SAE1 Protein, Human, Recombinant (His & GST) is expressed in Baculovirus insect cells with His and GST tag. The predicted molecular weight is 66.3 kDa and the accession number is Q9UBE0.
TMPJ-01116	HABP2 Protein, Human, Recombinant (His) Factor seven-activating protease,Factor VII-act...	Human	HEK293 Cells
	Hyaluronan-binding protein 2（HABP2） is an extracellular serine protease which binds hyaluronic acid. It secreted as an inactive single-chain precursor and is then activated to a heterodimeric form, which consists of a 50 kDa heavy and a 27 kDa light chain linked by a disulfide bond. HABP2 is involved in cell adhesion, it can cleave the alpha-chain at multiple sites and the beta-chain between 'Lys-53' and 'Lys-54' , but not the gamma-chain of fibrinogen. As a result of this, it does not initiate...
TMPH-02945	TMPRSS4 Protein, Mouse, Recombinant (His & SUMO) Channel-activating protease 4,Transmembrane proteas...	Mouse	E. coli
	Plasma membrane-anchored serine protease that directly induces processing of pro-uPA/PLAU into the active form through proteolytic activity. Seems to be capable of activating ENaC. TMPRSS4 Protein, Mouse, Recombinant (His & SUMO) is expressed in E. coli expression system with N-6xHis-SUMO tag. The predicted molecular weight is 57.8 kDa and the accession number is Q8VCA5.
TMPH-01508	HABP2 Protein, Human, Recombinant (His & SUMO) Hepatocyte growth factor activator-like protein,Factor VII-<...	Human	E. coli
	Cleaves the alpha-chain at multiple sites and the beta-chain between 'Lys-53' and 'Lys-54' but not the gamma-chain of fibrinogen and therefore does not initiate the formation of the fibrin clot and does not cause the fibrinolysis directly. It does not cleave (activate) prothrombin and plasminogen but converts the inactive single chain urinary plasminogen activator (pro-urokinase) to the active two chain form. Activates coagulation factor VII. May function as a tumor suppressor negatively regulat...
TMPY-06748	UBA6 Protein, Human, Recombinant (GST) ubiquitin-like modifier activating enzyme 6,UBE1L2,...	Human	Baculovirus Insect Cells
	UBA6 (Ubiquitin Like Modifier Activating Enzyme 6) is a Protein Coding gene. The UBA6 gene, located on 4q13.2, is conserved in chimpanzee, Rhesus monkey, dog, cow, mouse, rat, chicken, zebrafish, and frog. Uba6 is a homolog of the ubiquitin-activating enzyme, Uba1, and activates two ubiquitin-like proteins (UBLs), ubiquitin and FAT10. UBA6 is an alternative enzyme for ubiquitin activation in vertebrates that plays a pivotal role in early mouse development. UBA6 is widely expressed in the lymph n...
TMPH-03456	CAK1 Protein, S. cerevisiae, Recombinant (His & Myc) CAK1,CIV1,Serine/threonine-protein kinase CAK1,CDK-activ...	Saccharomyces cerevisiae	Baculovirus Insect Cells
	CAK1 Protein, S. cerevisiae, Recombinant (His & Myc) is expressed in Baculovirus insect cells with N-10xHis and C-Myc tag. The predicted molecular weight is 46.1 kDa and the accession number is P43568.
TMPH-03457	CAK1 Protein, S. cerevisiae, Recombinant (E. coli, His & Myc) Serine/threonine-protein kinase CAK1,CAK1,CDK-activating...	Saccharomyces cerevisiae	E. coli
	CAK1 Protein, S. cerevisiae, Recombinant (E. coli, His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 49.6 kDa and the accession number is P43568.
TMPY-02444	ATF2 Protein, Human, Recombinant (His & GST) CREB2,CRE-BP1,CREB-2,TREB7,activating transcription...	Human	Baculovirus Insect Cells
	Activating transcription factor 2, also known as ATF2, is a member of the leucine zipper family of DNA-binding proteins that binds to the cAMP response element. Its activity is enhanced after phosphorylation by stress-activated protein kinases such as c-Jun N-terminal kinase and p38. ATF2 has been found to be a target of the JNK signal transduction pathway and mediate adenovirus E1A-inducible transcriptional activation. ATF2 is also been reported playing roles in TGF-β signaling pathway. It has ...
TMPH-00164	4'-phosphopantetheinyl transferase ffp Protein, Bacillus subtilis, Recombinant (His & Myc) 4'-phosphopantetheinyl transferase ffp,EC:2.7.8.-,Fengycin s...	Bacillus subtilis	E. coli
	May activate the peptidyl carrier protein (PCP) domains of fengycin synthase by transferring the 4'-phosphopantetheinyl moiety of coenzyme A (CoA) to a serine residue. 4'-phosphopantetheinyl transferase ffp Protein, Bacillus subtilis, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 31.0 kDa and the accession number is Q9F4F7.
TMPH-01163	CXCL5 Protein, Human, Recombinant (His) Epithelial-derived neutrophil-activating protein 78...	Human	E. coli
	CXCL5 Protein, Human, Recombinant (His) is expressed in E. coli.
TMPJ-00425	NCR1 Protein, Mouse, Recombinant (hFc) NKp46,mNKp46,NK-p46,mAR-1,Lymphocyte antigen94,Activatin...	Mouse	HEK293 Cells
	Natural cytotoxicity triggering receptor 1(NKp46/NCR1) is a single-pass type I membrane protein. It consists of two extracellular Ig-like domains followed by a short stalk region, a transmembrane domain containing a positively charged amino acid residue, and a short cytoplasmictail. NKp46 is predominantly expressed in the embryo. It has a positive charge in its transmembrane domain that permits association with the ITAM-bearing signal adapter proteins, CD3 zeta and Fc epsilon RI gamma. These rec...
TMPH-00207	PTX S1 Protein, Bordetella pertussis, Recombinant (His) Islet-activating protein S1,Pertussis toxin subunit...	Bordetella pertussis	P. pastoris (Yeast)
	S1 is an NAD-dependent ADP-ribosyltransferase, which plays a crucial role in the pathogenesis of B.pertussis causing disruption of normal host cellular regulation. It catalyzes the ADP-ribosylation of a cysteine in the alpha subunit of host heterotrimeric G proteins. In the absence of G proteins it also catalyzes the cleavage of NAD(+) into ADP-ribose and nicotinamide. It irreversibly uncouples the G-alpha GTP-binding proteins from their membrane receptors. PTX S1 Protein, Bordetella pertussis, ...
TMPH-03518	ACP Protein, S. aureus, Recombinant (GST) acpP,Fatty acid synthase acyl carrier protein,Acyl carrier p...	Staphylococcus aureus	E. coli
	Carrier of the growing fatty acid chain in fatty acid biosynthesis. Is able to confer high methicillin resistance to S.aureus when overproduced. ACP Protein, S. aureus, Recombinant (GST) is expressed in E. coli expression system with N-GST tag. The predicted molecular weight is 35.5 kDa and the accession number is P0A001.
TMPH-03520	ACP Protein, S. aureus, Recombinant (His & SUMO) acpP,Cytosolic-activating factor,Fatty acid synthas...	Staphylococcus aureus	E. coli
	Carrier of the growing fatty acid chain in fatty acid biosynthesis. Is able to confer high methicillin resistance to S.aureus when overproduced. ACP Protein, S. aureus, Recombinant (His & SUMO) is expressed in E. coli expression system with N-6xHis-SUMO tag. The predicted molecular weight is 24.5 kDa and the accession number is P0A001.
TMPH-00572	ACP Protein, E. coli, Recombinant (His & SUMO) acpP,Fatty acid synthase acyl carrier protein,Cytosolic-...	E. coli	E. coli
	Carrier of the growing fatty acid chain in fatty acid biosynthesis.
TMPH-03519	ACP Protein, S. aureus, Recombinant (His) Cytosolic-activating factor,Fatty acid synthase acy...	Staphylococcus aureus	P. pastoris (Yeast)
	Carrier of the growing fatty acid chain in fatty acid biosynthesis. Is able to confer high methicillin resistance to S.aureus when overproduced. ACP Protein, S. aureus, Recombinant (His) is expressed in yeast with N-6xHis tag. The predicted molecular weight is 10.5 kDa and the accession number is P0A001.
TMPY-02648	PACAP receptor/ADCYAP1R1 Protein, Human, Recombinant (hFc) adenylate cyclase activating polypeptide 1 (pituita...	Human	HEK293 Cells
	Pituitary adenylate cyclase activating polypeptide (PACAP, Adcyap1) activation of PAC1 receptors ( Adcyap1r1) significantly increases excitability of guinea pig cardiac neurons. This modulation of excitability is mediated in part by plasma membrane G protein-dependent activation of adenylyl cyclase and downstream signaling cascades. Studies point to the potential role of the (pituitary) adenylate cyclase activating polypeptide receptor 1 (ADCYAP1R1) gene, which has been implicated in stress resp...
TMPH-00794	Dps Protein, Helicobacter pylori, Recombinant (His & SUMO) napA,DNA protection during starvation protein,Bacterioferrit...	Helicobacter pylori	E. coli
	Protects DNA from oxidative damage by sequestering intracellular Fe(2+) ion and storing it in the form of Fe(3+) oxyhydroxide mineral. One hydrogen peroxide oxidizes two Fe(2+) ions, which prevents hydroxyl radical production by the Fenton reaction. Required for the survival in the presence of oxidative stress. Dps is also a virulence factor that activates neutrophils, mast cells and monocytes. It binds to neutrophil-glycosphingolipids and to sulfated carbohydrates on mucin. It might have a role...
TMPY-02949	AP2 Gamma/TFAP2C Protein, Human, Recombinant (His) ERF1,hAP-2g,transcription factor AP-2 gamma (activating<...	Human	E. coli
	TFAP2C, also known as AP2-GAMMA, is a member of the activating protein 2 family of transcription factors. AP-2 factors bind to the consensus sequence 5'-GCCNNNGGC-3' and activate genes involved in a large spectrum of important biological functions including proper eye, face, body wall, limb and neural tube development. They also suppress a number of genes including MCAM/MUC18, C/EBP alpha and MYC. TFAP2C may be prognostic indicators for patients with breast tumors. TFAP2C gene has been tested fo...
TMPH-02239	TMPRSS4 Protein, Human, Recombinant (His & Myc) Channel-activating protease 2,TMPRSS4,Transmembrane...	Human	E. coli
	Plasma membrane-anchored serine protease that directly induces processing of pro-uPA/PLAU into the active form through proteolytic activity. Seems to be capable of activating ENaC.; (Microbial infection) In gut epithelial cells, facilitates human coronavirus SARS-CoV-2 infection through, at least, the cleavage of coronavirus spike glycoproteins which activates the glycoprotein for host cell entry. TMPRSS4 Protein, Human, Recombinant (His & Myc) is expressed in E. coli expression system with N-10...
TMPJ-00886	ATF1 Protein, Human, Recombinant (His) Cyclic AMP-dependent transcription factor ATF-1,Activati...	Human	E. coli
	Cyclic AMP-dependent transcription factor ATF-1(ATF1) which contains 1 bZIP (basic-leucine zipper) domain and 1 KID (kinase-inducible) domain, belongs to the bZIP family. It influences cellular physiologic processes by regulating the expression of downstream target genes, which are related to growth, survival, and other cellular activities. ATF1 binds the cAMP response element (CRE) (consensus: 5'-GTGACGT[AC][AG]-3'), a sequence present in many viral and cellular promoters. It also binds to the ...
TMPJ-00218	SLAMF6 Protein, Human, Recombinant (His & Avi), Biotinylated CD352,SLAM Family Member 6,Activating NK Receptor,N...	Human	HEK293 Cells
	SLAM Family Member 6 (SLAMF6) is a 60 kD single-pass type I membrane protein that belongs to the SLAM subgroup of the CD2 family. Human SLAMF6/ NTB-A contains a 205 amino acid extracellular domain (ECD) with one Ig-like V-set and one Ig-like C2-set domain, a 21 amino acid transmembrane segment and an 84 amino acid cytoplasmic domain, with two immunoreceptor tyrosine-based switch motifs. SLAMF6 is a homodimer. SLAMF6 can interact with PTN6 and, upon phosphorylation, with PTN11 and SH2D1A/SAP. Pho...
TMPH-01164	ATF-3 Protein, Human, Recombinant (His) ATF3,cAMP-dependent transcription factor ATF-3,Activatin...	Human	E. coli
	ATF3 Protein, Human, Recombinant (His) is expressed in E. coli.
TMPH-02997	Dps Protein, Mycobacterium smegmatis, Recombinant (His & SUMO) Neutrophil-activating protein A,NAP A,HP-NAP,Bacter...	Mycobacterium smegmatis	E. coli
	Protects DNA from oxidative damage by sequestering intracellular Fe(2+) ion and storing it in the form of Fe(3+) oxyhydroxide mineral. One hydrogen peroxide oxidizes two Fe(2+) ions, which prevents hydroxyl radical production by the Fenton reaction. It protects DNA from hydroxyl radical-mediated cleavage. Binds DNA with no apparent sequence specificity without self-aggregation nor promotion of DNA condensation. Is unable to protect DNA from DNase-mediated cleavage. Dps Protein, Mycobacterium sme...
TMPJ-01041	FGF-12 Protein, Human, Recombinant FGF12B,Myocyte-Activating Factor,FHF-1,FGF12,Fibrob...	Human	E. coli
	Fibroblast Growth Factor 12 (FGF-12) is a member of the fibroblast growth factor (FGF) family. FGF-12 is probably involved in nervous system development and function. FGF-12 lacks the N-terminal signal sequence present in most of the FGF family members, but it contains clusters of basic residues that have been demonstrated to act as a nuclear localization signal. When transfectedinto mammalian cells, this protein accumulated in the nucleus, but was not secreted. The specific function of this gen...
TMPH-00886	ATF7IP2 Protein, Human, Recombinant (His) MCAF2,ATF7-interacting protein 2,Activating transcr...	Human	E. coli
	Recruiter that couples transcriptional factors to general transcription apparatus and thereby modulates transcription regulation and chromatin formation. Can both act as an activator or a repressor depending on the context. Mediates MBD1-dependent transcriptional repression, probably by recruiting complexes containing SETDB1. The complex formed with MBD1 and SETDB1 represses transcription and probably couples DNA methylation and histone H3 'Lys-9' trimethylation (H3K9me3) activity (Probable). AT...
TMPH-01998	G3BP1 Protein, Human, Recombinant (His) ATP-dependent DNA helicase VIII,GAP SH3 domain-binding prote...	Human	E. coli
	G3BP1 Protein, Human, Recombinant (His) is expressed in E. coli.
TMPH-03274	ATF-4 Protein, Rat, Recombinant (His & Myc) cAMP-dependent transcription factor ATF-4,Activating	Rat	E. coli
	ATF-4 Protein, Rat, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 43.2 kDa and the accession number is Q9ES19.
TMPH-03740	DCL Protein, Bacillus subtilis, Recombinant (His) DCL,D-alanine--poly(phosphoribitol) ligase subunit 1,dltA,DA...	Bacillus subtilis	E. coli
	Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP-dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the...
TMPJ-01054	PAFAHB Protein, Human, Recombinant (His) PAFAH Subunit Beta,PAF-AH 30 kDa Subunit,Platelet-Activa...	Human	E. coli
	Platelet-Activating Factor Acetylhydrolase IB Subunit β (PAFAHB) is a cytoplasmic hydrolase. PAFAHB is a member of the GDSL lipolytic enzyme family. It also belongs to Platelet-activating factor acetylhydrolase IB beta/gamma subunits subfamily. Cytosolic PAF-AH IB is formed of three subunits of 45 kDa (alpha), 30 kDa (beta) and 29 kDa (gamma), PAFAHB is a catalytic subunit. PAFAHB inactivates PAF by removing the acetyl group at the sn-2 position.
TMPJ-00083	NCR3 Protein, Human, Recombinant (hFc) Activating Natural Killer Receptor p30,CD337,NKp30,...	Human	HEK293 Cells
	Natural Cytotoxicity Triggering Receptor 3 (NCR3) along with NKp44 and NKp46 constitute a group of receptors termed “Natural Cytotoxicity Receptors”. They play a major role in triggering NK-mediated killing of most tumor cells lines. NKp30 is a type I transmembrane protein having a single extracellular V-like immunoglobulin domain. NKp30 is selectively expressed both in resting and activated human NK cells. In addition, NKp30 is also involved in NK-mediated induction of dendritic cell (DC) matur...
TMPJ-00222	SLAMF7 Protein, Human, Recombinant (mFc) CD2 Subset 1,CRACC,CD319,CS1,Membrane Protein FOAP-12,SLAMF7...	Human	HEK293 Cells
	SLAMF7 Protein, Human, Recombinant (mFc) is expressed in HEK293 mammalian cells with C-mFc tag. The predicted molecular weight is 60-90 KDa and the accession number is Q9NQ25.
TMPJ-00120	NKp80/KLRF1 Protein, Human, Recombinant (His) Lectin-like receptor F1,C-type lectin domain family 5 member...	Human	HEK293 Cells
	Killer cell lectin-like receptor subfamily F member 1 (KLRF1) is known as NKp80. Human NKp80, a member of the C-type lectin family of proteins (1 - 3), is 231 aa in length with a 38 amino acid (aa) cytoplasmic region, a 21 aa transmembrane region, and a 172 aa extracellular domain (ECD). The protein strongly expressed in peripheral blood leukocytes and spleen, with weaker expression in lymph node and adult liver, and no expression detected in bone marrow, thymus, and fetal liver. Its' function i...
TMPJ-00920	CD40 Ligand Protein, Mouse, Recombinant (aa 112-260, His) TNFSF5,Tumor necrosis factor ligand superfamily member 5,CD4...	Mouse	HEK293 Cells
	CD40 Ligand, also known as TNFSF5, CD154, is a type II transmembrane glycoprotein member of the TNF superfamily. Mature mouse CD40 Ligand consists of a 22 amino acid (aa) cytoplasmic domain, a transmembrane segment, and a 214 aa extracellular region. CD40 Ligand is expressed as a homotrimer on platelets and activated T cells and B cells. It is upregulated following stimulation of basophils, eosinophils, fibroblasts, mast cells, monocytes, natural killer cells, vascular endothelial cells, and sm...
TMPJ-01442	SLAMF7 Protein, Rhesus macaque, Recombinant (His) CD2 Subset 1,CD2-Like Receptor-Activating Cytotoxic...	Rhesus	HEK293 Cells
	SLAMF7 Protein, Rhesus macaque, Recombinant (His) is expressed in HEK293 mammalian cells with C-6xHis tag. The predicted molecular weight is 30-50 KDa and the accession number is F7HQ72.
TMPJ-00221	SLAMF7 Protein, Human, Recombinant (His & Avi), Biotinylated Membrane Protein FOAP-12,Novel Ly9,CRACC,SLAMF7,SLAM Family ...	Human	HEK293 Cells
	SLAMF7 Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with C-6xHis-Avi tag. The predicted molecular weight is 35-55 KDa and the accession number is Q9NQ25.
TMPJ-00567	NCR1 Protein, Human, Recombinant (hFc) hNKp46,Natural cytotoxicity triggering receptor 1,NCR1,Natur...	Human	HEK293 Cells
	Natural cytotoxicity triggering receptor 1(NCR1) is a single-pass type I membrane protein .It contains 2 Ig-like (immunoglobulin-like) domains and belongs to the natural cytotoxicity receptor (NCR) family. The protein is a natural killer (NK) lymphocyte-activating receptor. It is involved in major aspects of NK immune function and shows a high degree of lineage specificity in blood and bone marrow.
TMPJ-00178	BAFF/TNFSF13B Protein, Human, Recombinant (His) B lymphocyte stimulator,TNF- and APOL-related leukocyte expr...	Human	HEK293 Cells
	BAFF/TNFSF13B Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with N-6xHis tag. The predicted molecular weight is 22 KDa and the accession number is Q9Y275.
TMPJ-00553	Lp-PLA2/PLA2G7 Protein, Human, Recombinant (aa 22-441, His) PAF Acetylhydrolase,LDL-Associated Phospholipase A2,LDL-PLA(...	Human	HEK293 Cells
	Platelet-Activating Factor Acetylhydrolase (PAFAH) is a secreted enzyme which belongs to the AB hydrolase superfamily and Lipase family and catalyzes the degradation of platelet-activating factor to biologically inactive products. PAFAH is produced by inflammatory cells and hydrolyzes oxidised phospholipids in LDL. PAFAH has been implicated in the development of atherosclerosis and has also been identified as a marker for cardiac disease. PAFAH might have a major physiologic effect in the presen...
TMPJ-00009	CCL2 Protein, Human, Recombinant C-C motif chemokine 2,MCAF,CCL2,MCP-1,Monocyte chemotactic p...	Human	E. coli
	The chemokine (C-C motif) ligand 2 (CCL2), also known as monocyte chemoattractant protein (MCP)-1 and small inducible cytokine A2 (SCYA2)), is a small cytokine that belongs to the CC chemokine family responsible for monocyte attraction. Its cognate receptor, CCR2, play a critical role in regulating nociceptive processes during neuropathic pain. Both CCL2 and CCR2 are implicated in induction of autoimmunity. CCL2 recruits monocytes, memory T cells, and dendritic cells to the sites of inflammation...
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重组蛋白

SAE1 Protein, Human, Recombinant

Cat.No: TMPY-03441

Species: Human

Expression System: Baculovirus Insect Cells

Ubiquitin Activating Enzyme E1/UBA1 Protein, Human, Recombinant (His & GST)

Cat.No: TMPY-02840

Species: Human

Expression System: Baculovirus Insect Cells

FGF-9 Protein, Mouse, Recombinant (His)

Cat.No: TMPJ-01011

Species: Mouse

Expression System: E. coli

FGF-9 Protein, Human, Recombinant

Cat.No: TMPJ-00090

Species: Human

Expression System: E. coli

UBA5 Protein, Human, Recombinant (His)

Cat.No: TMPJ-01324

Species: Human

Expression System: E. coli

BAFF/TNFSF13B Protein, Mouse, Recombinant (mFc)

Cat.No: TMPJ-01391

Species: Mouse

Expression System: HEK293 Cells

FLAP Protein, Human, Recombinant (His)

Cat.No: TMPY-01481

Species: Human

Expression System: Baculovirus Insect Cells

SYNGAP1 Protein, Human, Recombinant (His)

Cat.No: TMPH-01997

Species: Human

Expression System: E. coli

PLAA Protein, Mouse, Recombinant (His & Myc)

Cat.No: TMPH-02828

Species: Mouse

Expression System: Baculovirus Insect Cells

SFP Protein, B.subtilis, Recombinant (His)

Cat.No: TMPJ-00611

Species: Bacillus subtilis

Expression System: E. coli

SAE1 Protein, Human, Recombinant (His & GST)

Cat.No: TMPY-03062

Species: Human

Expression System: Baculovirus Insect Cells

HABP2 Protein, Human, Recombinant (His)

Cat.No: TMPJ-01116

Species: Human

Expression System: HEK293 Cells

TMPRSS4 Protein, Mouse, Recombinant (His & SUMO)

Cat.No: TMPH-02945

Species: Mouse

Expression System: E. coli

HABP2 Protein, Human, Recombinant (His & SUMO)

Cat.No: TMPH-01508

Species: Human

Expression System: E. coli

UBA6 Protein, Human, Recombinant (GST)

Cat.No: TMPY-06748

Species: Human

Expression System: Baculovirus Insect Cells

CAK1 Protein, S. cerevisiae, Recombinant (His & Myc)

Cat.No: TMPH-03456

Species: Saccharomyces cerevisiae

Expression System: Baculovirus Insect Cells

CAK1 Protein, S. cerevisiae, Recombinant (E. coli, His & Myc)

Cat.No: TMPH-03457

Species: Saccharomyces cerevisiae

Expression System: E. coli

ATF2 Protein, Human, Recombinant (His & GST)

Cat.No: TMPY-02444

Species: Human

Expression System: Baculovirus Insect Cells

4'-phosphopantetheinyl transferase ffp Protein, Bacillus subtilis, Recombinant (His & Myc)

Cat.No: TMPH-00164

Species: Bacillus subtilis

Expression System: E. coli

CXCL5 Protein, Human, Recombinant (His)

Cat.No: TMPH-01163

Species: Human

Expression System: E. coli

NCR1 Protein, Mouse, Recombinant (hFc)

Cat.No: TMPJ-00425

Species: Mouse

Expression System: HEK293 Cells

PTX S1 Protein, Bordetella pertussis, Recombinant (His)

Cat.No: TMPH-00207

Species: Bordetella pertussis

Expression System: P. pastoris (Yeast)

ACP Protein, S. aureus, Recombinant (GST)

Cat.No: TMPH-03518

Species: Staphylococcus aureus

Expression System: E. coli

ACP Protein, S. aureus, Recombinant (His & SUMO)

Cat.No: TMPH-03520

Species: Staphylococcus aureus

Expression System: E. coli

ACP Protein, E. coli, Recombinant (His & SUMO)

Cat.No: TMPH-00572

Species: E. coli

Expression System: E. coli

ACP Protein, S. aureus, Recombinant (His)

Cat.No: TMPH-03519

Species: Staphylococcus aureus

Expression System: P. pastoris (Yeast)

PACAP receptor/ADCYAP1R1 Protein, Human, Recombinant (hFc)

Cat.No: TMPY-02648

Species: Human

Expression System: HEK293 Cells

Dps Protein, Helicobacter pylori, Recombinant (His & SUMO)

Cat.No: TMPH-00794

Species: Helicobacter pylori

Expression System: E. coli

AP2 Gamma/TFAP2C Protein, Human, Recombinant (His)

Cat.No: TMPY-02949

Species: Human

Expression System: E. coli

TMPRSS4 Protein, Human, Recombinant (His & Myc)

Cat.No: TMPH-02239

Species: Human

Expression System: E. coli

ATF1 Protein, Human, Recombinant (His)

Cat.No: TMPJ-00886

Species: Human

Expression System: E. coli

SLAMF6 Protein, Human, Recombinant (His & Avi), Biotinylated

Cat.No: TMPJ-00218

Species: Human

Expression System: HEK293 Cells

ATF-3 Protein, Human, Recombinant (His)

Cat.No: TMPH-01164

Species: Human

Expression System: E. coli

Dps Protein, Mycobacterium smegmatis, Recombinant (His & SUMO)

Cat.No: TMPH-02997

Species: Mycobacterium smegmatis

Expression System: E. coli

FGF-12 Protein, Human, Recombinant

Cat.No: TMPJ-01041

Species: Human

Expression System: E. coli

ATF7IP2 Protein, Human, Recombinant (His)

Cat.No: TMPH-00886

Species: Human

Expression System: E. coli

G3BP1 Protein, Human, Recombinant (His)

Cat.No: TMPH-01998

Species: Human

Expression System: E. coli

ATF-4 Protein, Rat, Recombinant (His & Myc)

Cat.No: TMPH-03274

Species: Rat

Expression System: E. coli

DCL Protein, Bacillus subtilis, Recombinant (His)

Cat.No: TMPH-03740

Species: Bacillus subtilis

Expression System: E. coli

PAFAHB Protein, Human, Recombinant (His)

Cat.No: TMPJ-01054

Species: Human

Expression System: E. coli

NCR3 Protein, Human, Recombinant (hFc)

Cat.No: TMPJ-00083

Species: Human

Expression System: HEK293 Cells

SLAMF7 Protein, Human, Recombinant (mFc)

Cat.No: TMPJ-00222

Species: Human

Expression System: HEK293 Cells

NKp80/KLRF1 Protein, Human, Recombinant (His)

Cat.No: TMPJ-00120

Species: Human

Expression System: HEK293 Cells

CD40 Ligand Protein, Mouse, Recombinant (aa 112-260, His)

Cat.No: TMPJ-00920

Species: Mouse

Expression System: HEK293 Cells

SLAMF7 Protein, Rhesus macaque, Recombinant (His)

Cat.No: TMPJ-01442

Species: Rhesus

Expression System: HEK293 Cells

SLAMF7 Protein, Human, Recombinant (His & Avi), Biotinylated

Cat.No: TMPJ-00221

Species: Human

Expression System: HEK293 Cells

NCR1 Protein, Human, Recombinant (hFc)

Cat.No: TMPJ-00567

Species: Human

Expression System: HEK293 Cells

BAFF/TNFSF13B Protein, Human, Recombinant (His)

Cat.No: TMPJ-00178

Species: Human

Expression System: HEK293 Cells

Lp-PLA2/PLA2G7 Protein, Human, Recombinant (aa 22-441, His)

Cat.No: TMPJ-00553

Species: Human

Expression System: HEK293 Cells

CCL2 Protein, Human, Recombinant

Cat.No: TMPJ-00009

Species: Human

Expression System: E. coli

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Cat. No.	Product Name	Target	Signaling Pathways
TMIH-0102	Avatrombopag-d8
	Avatrombopag-d8 是 Avatrombopag 的氘代化合物。Avatrombopag 的 CAS 号为 570406-98-3。Avatrombopag 是一种新型口服血小板生成素 (TPO) 受体激动剂，可激活 TPO 受体并增加巨核细胞增殖/分化和血小板生成。
TMID-0233	Salbutamol-d9
	Salbutamol-d9 是 Salbutamol 的氘代化合物。Salbutamol 的 CAS 号为 18559-94-9。Salbutamol 是短效的 β2 肾上腺素受体激动剂，用于哮喘和慢性阻塞性肺疾病 (COPD) 引发的支气管痉挛的研究。
T67921	Retinoic acid-d5 all-trans-Retinoic acid-d5,Isotretinoin-d5,Vitamin A acid-d5,Accutane-d5,ATRA-d5	Retinoid Receptor	Metabolism
	Retinoic acid-d5 (Vitamin A acid-d5)是视黄酸的氘标记形式。视黄酸是一种天然的RAR 核受体激动剂，对 RARα/β/γ 的 IC50 为 14 nM，与 PPARβ/δ 结合的Kd 为 17 nM。视黄酸是维生素a 的代谢物，在细胞生长、分化和器官发育中起着重要作用。视黄酸通过激活视黄酸受体α作为转录因子Nrf2的抑制剂来发挥作用。
TMIH-0512	Salbutamol-d3
	Salbutamol-d3 是 Salbutamol 的氘代化合物。Salbutamol 的 CAS 号为 18559-94-9。Salbutamol 是短效的 β2 肾上腺素受体激动剂，用于哮喘和慢性阻塞性肺疾病 (COPD) 引发的支气管痉挛的研究。
T70882	Orlistat-d3
	Orlistat-d3 is intended for use as an internal standard for the quantification of orlistat by GC- or LC-MS. Orlistat is a digestive lipase inhibitor. It inhibits diacylglycerol lipase α (DAGLα), DAGLβ, α/β-hydrolase domain-containing protein 12 (ABHD12), ABHD16A, and platelet-activating factor acetylhydrolase (PAF-AH; IC50s = 0.06, 0.1, 0.08, 0.03, and 0.05 µM, respectively), as well as pancreatic lipase and hormone-sensitive lipase (IC50s = 0.65 and 2.1 µg/ml, respectively) but does not inhibit...
TMID-0254	Linalool-d3
	Linalool-d3 是 Linalool 的氘代化合物。Linalool 的 CAS 号为 78-70-6。Linalool 是存在芫荽等植物中的单萜类天然产物，是竞争性NMDA受体拮抗剂，具有抗肿瘤和抗心脏毒性的作用。它通过激活 Nrf2 诱导抗氧化防御和通过抑制 NF-κB 减少炎症反应来保护其免受 LPS/GalN 诱导的肝损伤，具有镇痛、抗菌和抗炎的特性。

同位素标记化合物

Avatrombopag-d8

Cat.No: TMIH-0102

Cat.No: TMID-0233

Retinoic acid-d5

Cat.No: T67921

Synonym: all-trans-Retinoic acid-d5,Isotretinoin-d5,Vitamin A acid-d5,Accutane-d5,ATRA-d5

Target: Retinoid Receptor

Cat.No: TMIH-0512

Cat.No: T70882

Cat.No: TMID-0254

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