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Targets Recommended: Others

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Cat. No. Product Name Target Signaling Pathways
T35475 aTAG 4531

Others Others
Degrader of MTH1 fusion proteins for use within the aTAG system. Comprises a ligand selective for MTH1, a linker and the cereblon-binding ligand Thalidomide . Induces highly potent and selective degradation of fusion proteins after a 4 h incubation (DC50 = 0.34 nM; Dmax = 93.14%). Cell-permeable. Suitable for in vitro and in vivo applications. Mouse DMPK properties are provided in the supplementary file (see below). (MTH1 can be expressed as a fusion with a target protein of interest using genom...

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aTAG 4531
Cat.No: T35475
Synonym:
Target: Others
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