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Cat. No.	Product Name	Target	Signaling Pathways
TN2010	Ombuin 商陆黄素,商陆素	Antibacterial	Microbiology/Virology
	Ombuin 是一种从花椒中分离出的广谱抗菌剂，MIC 为 125 至 500 μg/mL。
TN1089	Hydroxy-β-sanshool Hydroxy-beta-sanshool	Others	Others
	Hydroxy-β-sanshool 是一种从胡椒中提取的辛辣化合物。
TN1174	Schinifoline	Apoptosis; cell cycle arrest	Apoptosis; Cell Cycle/Checkpoint
	Schinifoline 是从 Zanthoxylum schinifolium Sieb 中提取出来的一种喹啉酮衍生物，具有细胞毒性活性，可促进癌细胞放射敏感性，影响细胞循环周期和细胞凋亡。
T5S1959	(-)-Asarinin Fagarol,Sesamin,细辛脂素,Pseudocubebin,Eleutheroside B4,Episesamin,Asarinin	Antibacterial	Microbiology/Virology
	(-)-Asarinin (Eleutheroside B4) 是一种主要从 Zanthoxylum armatum 根部提取到的木脂素。
T8859	NITIDINE	Others	Others
	NITIDINE 是一种从花椒根中分离出来的具有生物活性的植物苯并菲啶生物碱。它具有抗癌、神经保护、抗疟疾、抗 HIV、镇痛、抗炎和抗真菌活性。
T2981	Xanthoxylin Brevifolin,Xanthoxyline,花椒素,2'-Hydroxy-4',6'-dimethoxyacetophenone	Others; Antifungal	Microbiology/Virology; Others
	Xanthoxylin (Brevifolin)e 是从Zanthoxylum simulans 中分离出来的是一种冰片和樟脑味化合物，有抗真菌和抗癫痫作用。
T5S0761	Nitidine chloride	Apoptosis; ERK; FAK; p38 MAPK; NF-κB; Topoisomerase; STAT; Parasite	Angiogenesis; Apoptosis; Cytoskeletal Signaling; DNA Damage/DNA Repair; JAK/STAT signaling; MAPK; Microbiology/Virology; NF-κB; Stem Cells; Tyrosine Kinase/Adaptors
	Nitidine chloride 是从Zanthoxylum nitidum (Roxb) DC 中分离得到的，具有抗疟疾活性。它通过多个靶点通路，起抗癌作用，抑制STAT3、DNA 拓扑异构酶1和2A、ERK 和c-Src/FAK 相关信号通路。它通过MAPK 和NF-kB 途径抑制Lps 诱导的炎性细胞因子的产生。
TN3047	4-Methoxy-1-methylquinolin-2-one	Others	Others
	4-Methoxy-1-methylquinolin-2-one is a natural product from Zanthoxylum nitidum.
T82553	Dihydronitidine
	Dihydronitidine是从Zanthoxylum rhoifolium中提取的一种生物碱。
T3833	Sanshodiol	Others	Others
	Sanshodiol是一种天然产物，属于芸香科花椒属，其产品编号为 T3833，CAS号为 54854-91-0。Sanshodiol可用作对照参考。
TN4687	O-Geranylconiferyl alcohol	Others	Others
	O-Geranylconiferyl alcohol是一种天然产物，属于芸香科花椒属，其产品编号为 TN4687，CAS号为 129350-09-0。O-Geranylconiferyl alcohol可用作对照参考。
T13732	Hydroxy-Epsilon-Sanshool	Others	Others
	Hydroxy-Epsilon-Sanshool is an alkyl amide isolated from Zanthoxylum bungeanum. Hydroxy-Epsilon-Sanshool produces key tingling and numbing chemosensation.
T19557	Sanshool	Others	Others
	Sanshool is a natural product isolated from Zanthoxylum bungeanum. Sanshool improves UVB-induced skin photodamage by targeting JAK2/STAT3-dependent autophagy.
TN2408	Evofolin B	Cannabinoid Receptor	GPCR/G Protein
	Evofolin B 是从Zanthoxylum ailanthoides 的茎皮中分离出来的天然化合物。Evofolin B 对人类中性粒细胞对甲酰-L-蛋氨酸-L-亮氨酸-L-苯丙氨酸/cytochalasin B（fMLP/CB）产生的超氧阴离子有抑制作用。
TN2159	Robustine 大叶桉亭,8-羟基白鲜碱,4-甲氧基呋喃并[2,3-B]喹啉-8-醇	PDE	Metabolism
	Robustine 是一种从 Dictamnus albus 获得的呋喃喹啉生物碱，在体外对人磷酸二酯酶 5 (hPDE5A) 具有抑制作用。
T8307	Hydroxy-α-sanshool 羟基-α-山椒素,Hydroxy-α-sanshool	Endogenous Metabolite; TRP/TRPV Channel	Membrane transporter/Ion channel; Metabolism
	Hydroxy-α-sanshool 是分离自胡椒的烷基酰胺，作为 TRPA1的共价激动剂和 TRPV1的非共价激动剂，EC50分别为69和 1.1 µM。
TN4931	L-Citronellol (S)-(-)-beta-Citronellol,(S)-(-)-β-Citronellol	Antifungal	Microbiology/Virology
	L-Citronellol ((S)-(-)-beta-Citronellol) 是一种从天竺葵中分离到的小分子化合物，具有抗真菌活性，会对真菌膜产生影响。L-Citronellol 在对念珠菌酵母菌作用时与两性霉素B具有协同作用。
T38330	Collinin	Others	Others
	Collinin is a coumarin that has been found in Z. schinifolium and has diverse biological activities.1,2,3,4 It is active against drug-susceptible and -resistant strains of M. tuberculosis (MIC50s = 3.13-6.25 μg/ml).1 Collinin inhibits LPS-induced nitric oxide (NO) production (IC50 = 5.9 μM) and reduces COX-2 protein levels in RAW 264.7 cells.2 It completely inhibits aggregation of isolated rabbit platelets induced by arachidonic acid , collagen, or platelet activating factor (PAF) when used at a...
TN5264	Xanthoxyletin	TNF; NOS; ROS; COX; Antifection	Apoptosis; Immunology/Inflammation; Microbiology/Virology; Neuroscience
	Xanthoxyletin shows potent antibacterial, fungicidal, and algicidal properties, it also has anticancer, and anti-inflammatory activities. It shows an inhibitory effect on iNOS protein expression at 10 microM, it also can inhibit the synthesis of nitric oxide and the protein expression of tumor necrosis factor-alpha and cyclooxygenase-2. Xanthoxyletin induces S phase arrest and apoptosis in human gastric adenocarcinoma SGC-7901 cells, the effects are associated with the DNA damage, apoptosis thro...
TN2692	2,3-Di(3',4'-methylenedioxybenzyl)-2-buten-4-olide	Others	Others
	2,3-Di(3',4'-methylenedioxybenzyl)-2-buten-4-olide 是一种天然产物，可用于生命科学领域的相关研究。其产品编号为 TN2692，CAS号为 137809-97-3。
TN6703	Methyl (E)-cinnamate Methyl trans-cinnamate
	Methyl (E)-cinnamate 是一种天然产物，可用于生命科学领域的相关研究。其产品编号为 TN6703，CAS号为 1754-62-7。
TN3366	Ailanthoidol	IL Receptor; NOS; COX; Prostaglandin Receptor; PPAR	DNA Damage/DNA Repair; GPCR/G Protein; Immunology/Inflammation; Metabolism; Neuroscience
	Ailanthoidol has anti-inflammatory activity, it inhibits inflammatory reactions by macrophages and protects mice from endotoxin shock. It also possesses potential as a chemopreventive agent against tumor promotion. Ailanthoidol has anti-adipogenic activit
TN6056	Zanthobungeanine 8-Methoxy-N-methylflindersine
	Zanthobungeanine has anti-inflammatory activity, it shows moderate NO production inhibitory activity with an IC50 value of 37.26 mg /L.It shows obviously inhibitoryactivity to platelet aggregation caused by platelet-activating factor (PAF). Zanthobungeani
TN1090	Hydroxy-γ-sanshool Hydroxy-gamma-sanshool,羟基-γ-山椒素	Others	Others
	Hydroxy-γ-sanshool is a pungent compound, it can cause oral numbness.
TN3076	5-(3-Hydroxypropyl)-7-methoxybenzofuran	Others	Others
	5-(3-Hydroxypropyl)-7-methoxybenzofuran 是一种天然产物，可用于生命科学领域的相关研究。其产品编号为 TN3076，CAS号为 118930-92-0。
TN5653	Cnidioside B methyl ester
	Cnidioside B exerts little immunomodulatory effect in RAW 264.7 cells.
TN4590	Mullilam diol	Others	Others
	Mullilam diol 是一种天然产物，可用于生命科学领域的相关研究。其产品编号为 TN4590，CAS号为 36150-04-6。
TN1834	Kobusin 去甲槟郎碱,自旋七叶素	Others; NOS; NF-κB	Immunology/Inflammation; NF-κB; Others
	Kobusin, a Calmodulin inhibitor, shows mild antiplasmodial,anti-inflammatory, and cytotoxic activities; it may be beneficial for the treatment of neuro-inflammatory diseases through the inhibition of iNOS expression and peroxynitrite scavenging potential. Kobusin can mildly reduce gastrointestinal motility in mice, it activates CFTR and CaCCgie chloride channel activities in mouse colonic epithelia and shows inhibitory effects toward ANO1/CaCC-mediated short-circuit currents in ANO1/CaCC-express...
TN1138	γ-Fagarine γ-崖椒碱,gamma-Fagarine	HCV Protease	Microbiology/Virology; Proteases/Proteasome
	gamma-Fagarine possesses moderate levels of anti-HCV activities with IC50 values being 20.4 ± 0.4 ug/ml, respectively. It has sister chromatid exchanges (SCEs)-inducing activity
TN1556	Decarine	Antifection	Microbiology/Virology
	Decarine has high antibacterial activity against mycobacterial, gram-positive and gram-negative bacteria, and low cytotoxicity towards human macrophages.Decarine inhibits fMLP/CB-induced elastase release with IC(50) values < or = 5.53 microg/mL.

天然产物

Cat.No: TN2010

Synonym: 商陆黄素,商陆素

Target: Antibacterial

Hydroxy-β-sanshool

Cat.No: TN1089

Synonym: Hydroxy-beta-sanshool

Target: Others

Cat.No: TN1174

Target: Apoptosis, cell cycle arrest

Cat.No: T5S1959

Synonym: Fagarol,Sesamin,细辛脂素,Pseudocubebin,Eleutheroside B4,Episesamin,Asarinin

Target: Antibacterial

Cat.No: T8859

Target: Others

Cat.No: T2981

Synonym: Brevifolin,Xanthoxyline,花椒素,2'-Hydroxy-4',6'-dimethoxyacetophenone

Target: Others, Antifungal

Nitidine chloride

Cat.No: T5S0761

Target: Apoptosis, ERK, FAK, p38 MAPK, NF-κB, Topoisomerase, STAT, Parasite

4-Methoxy-1-methylquinolin-2-one

Cat.No: TN3047

Target: Others

Dihydronitidine

Cat.No: T82553

Cat.No: T3833

Target: Others

O-Geranylconiferyl alcohol

Cat.No: TN4687

Target: Others

Hydroxy-Epsilon-Sanshool

Cat.No: T13732

Target: Others

Cat.No: T19557

Target: Others

Cat.No: TN2408

Target: Cannabinoid Receptor

Cat.No: TN2159

Synonym: 大叶桉亭,8-羟基白鲜碱,4-甲氧基呋喃并[2,3-B]喹啉-8-醇

Target: PDE

Hydroxy-α-sanshool

Cat.No: T8307

Synonym: 羟基-α-山椒素,Hydroxy-α-sanshool

Target: Endogenous Metabolite, TRP/TRPV Channel

Cat.No: TN4931

Synonym: (S)-(-)-beta-Citronellol,(S)-(-)-β-Citronellol

Target: Antifungal

Cat.No: T38330

Target: Others

Cat.No: TN5264

Target: TNF, NOS, ROS, COX, Antifection

2,3-Di(3',4'-methylenedioxybenzyl)-2-buten-4-olide

Cat.No: TN2692

Target: Others

Methyl (E)-cinnamate

Cat.No: TN6703

Synonym: Methyl trans-cinnamate

Cat.No: TN3366

Target: IL Receptor, NOS, COX, Prostaglandin Receptor, PPAR

Zanthobungeanine

Cat.No: TN6056

Synonym: 8-Methoxy-N-methylflindersine

Hydroxy-γ-sanshool

Cat.No: TN1090

Synonym: Hydroxy-gamma-sanshool,羟基-γ-山椒素

Target: Others

5-(3-Hydroxypropyl)-7-methoxybenzofuran

Cat.No: TN3076

Target: Others

Cnidioside B methyl ester

Cat.No: TN5653

Cat.No: TN4590

Target: Others

Cat.No: TN1834

Synonym: 去甲槟郎碱,自旋七叶素

Target: Others, NOS, NF-κB

Cat.No: TN1138

Synonym: γ-崖椒碱,gamma-Fagarine

Target: HCV Protease

Cat.No: TN1556

Target: Antifection

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