Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T12635L |
Plevitrexed
BGC9331,ZD 9331 |
Others | Others |
Plevitrexed is taken up via the α-folate receptor as well as the reduced folate carrier. Plevitrexed is an orally active and effective thymidylate synthase (TS) inhibitor (Ki: 0.44 nM). Plevitrexed is used for gastric cancer in clinical. | |||
T12674 |
(Rac)-Plevitrexed
(Rac)-ZD 9331,(Rac)-BGC9331 |
Others | Others |
(Rac)-Plevitrexed is a racemate of Plevitrexed. Plevitrexed is an orally active and potent inhibitor of thymidylate synthase (TS). | |||
T12635 |
(R)-Plevitrexed
(R)-ZD 9331,(R)-BGC9331,(R)-普来曲塞 |
Others | Others |
(R)-Plevitrexed is a less active enantiomer of Plevitrexed. Plevitrexed is an orally active and potent inhibitor of thymidylate synthase (TS). |