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Targets Recommended: Others

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Cat. No. Product Name Target Signaling Pathways
T71915 Z1913661252

Others Others
Z1913661252 is a novel riboswitch activator, binding ZTP riboswitches, and activating transcription more strongly than ZMP in vitro.
T70180 LFS-829

Others Others
LFS-829 is a a small-molecule antagonist of exportin-1. LFS-829 showed low-range nanomolar activities. Oral administration of LFS-829 can significantly reverse the pathological features of colitis model mice. LFS-829 can attenuate dual NF-κB signaling and the Nrf2 cytoprotection pathway via targeting exportin-1 in colitis mice. Moreover, LFS-829 has a very low risk of cardiotoxicity and acute toxicity. LFS-829 holds great promise for the treatment of colitis and may warrant translation for use i...

化合物

Z1913661252
Cat.No: T71915
Synonym:
Target: Others
LFS-829
Cat.No: T70180
Synonym:
Target: Others
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