Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
TN2322 |
Yangambin
|
Calcium Channel; PAFR | GPCR/G Protein; Membrane transporter/Ion channel; Metabolism |
Yangambin 是从诸如番荔枝科植物中分离出来的呋喃木脂素,是选择性PAF 受体拮抗剂,通过调控Ca2+通道抑制 Ca2+流入,导致 [Ca2+]i 在血管平滑肌细胞和随后的外周血管舒张中减少,具有降压作用。 | |||
TN3979 | Epiyangambin | PAFR | GPCR/G Protein |
Epiyangambin is a phytotoxic lignan, it shows inhibition of seed germination of Agrostis stolonifera cv. penncross (Poaceae) and inhibition of development of Lactuca sativa L. (Asteraceae) seedlings in a microassay using 24-well plates. Epiyangambin exhibits significant inhibition of the transformation of murine epidermal JB6 cells, with the IC50 value of 0.15 microg/mL. (+)-Epiyangambin also has anti-platelet aggregation activity. | |||
TN3778 |
De-4'-O-methylyangambin
|
Antifection | Microbiology/Virology |
De-4'-O-methylyangambin exhibits antibacterial effects. It also has analgesia activity. | |||
T82565 |
Diayangambin
Syringaresinol dimethyl ether,Lirioresinol C dimethyl ether |
||
Diayangambin (Syringaresinol dimethyl ether; Lirioresinol C dimethyl ether) 作为一种细胞增殖抑制剂,其对人单核细胞的IC50值为1.5 μM。此外,Diayangambin 还表现出免疫抑制与抗炎特性。 |