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Targets Recommended: Others

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Cat. No. Product Name Target Signaling Pathways
T70446 Abivertinib HCl

Others Others
Abivertinib, also known as AC0010 and Avitinib, is a third-generation EGFR tyrosine kinase inhibitor and BTK Inhibitor that demonstrated clinical efficacy and manageable adverse events (AEs). Abivertinib inhibits cell proliferation, reduces colony-forming capacity, and induces apoptosis and cell cycle arrest in AML cells, especially those harboring FLT3-ITD mutations. Abivertinib was also found to be more sensitive than ibrutinib in treating AML. Abivertinib may be a promising novel agent for A...

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Abivertinib HCl
Cat.No: T70446
Synonym:
Target: Others
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