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Targets Recommended: Others

1

抑制剂 & 化合物

2

重组蛋白

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Cat. No. Product Name Target Signaling Pathways
T13359 XPC-6444

Others Others
XPC-6444 is a isoform-selective, and CNS-penetrant inhibitor of NaV1.6 with IC50 of41 nM for hNaV1.6,with anticonvulsant activity.

化合物

XPC-6444
Cat.No: T13359
Synonym:
Target: Others
Cat. No. Product Name Species Expression System
TMPH-01239 XPC Protein, Human, Recombinant (His)

Xeroderma pigmentosum group C-complementing protein,p125,

Human E. coli
Involved in global genome nucleotide excision repair (GG-NER) by acting as damage sensing and DNA-binding factor component of the XPC complex. Has only a low DNA repair activity by itself which is stimulated by RAD23B and RAD23A. Has a preference to bind DNA containing a short single-stranded segment but not to damaged oligonucleotides. This feature is proposed to be related to a dynamic sensor XPC can rapidly screen duplex DNA for non-hydrogen-bonded bases by forming a transient nucleoprotein i...
TMPH-02300 RAD23A Protein, Human, Recombinant (His)

UV excision repair protein RAD23 homolog A,RAD23A

Human E. coli
Multiubiquitin chain receptor involved in modulation of proteasomal degradation. Binds to 'Lys-48'-linked polyubiquitin chains in a length-dependent manner and with a lower affinity to 'Lys-63'-linked polyubiquitin chains. Proposed to be capable to bind simultaneously to the 26S proteasome and to polyubiquitinated substrates and to deliver ubiquitinated proteins to the proteasome.; Involved in nucleotide excision repair and is thought to be functional equivalent for RAD23B in global genome nucle...

重组蛋白

XPC Protein, Human, Recombinant (His)
Cat.No: TMPH-01239
Species: Human
Expression System: E. coli
RAD23A Protein, Human, Recombinant (His)
Cat.No: TMPH-02300
Species: Human
Expression System: E. coli
TargetMol Loading
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