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Search Results for " x-ray "

Targets Recommended: Others

14

抑制剂 & 化合物

1

化合物库

5

重组蛋白

1

同位素标记化合物

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Cat. No.	Product Name
L5700	精选片段库		246 compounds
	xnum 个片段小分子的独特集合，可用于基于片段的筛选和药物发现（FBDD）；

化合物库

精选片段库

Cat.No: L5700

Compounds: 246

Cat. No.	Product Name	Target	Signaling Pathways
T19376	Ioversol MP-328,碘佛醇	Others	Others
	Ioversol (MP-328) 是一种非离子碘化造影剂 (CM)，不损伤动物的血脑屏障 (BBB)，可用于动物实验的 CT 扫描或 x-ray。
T1576	Iopamidol SQ-13396,Niopam,Iopamiron,Iopamiro,碘帕醇,B-15000,Isovue	Others	Others
	Iopamidol (SQ-13396) 是一种 benzenedicarboxamide 化合物。它具有放射性不透明介质、环境污染物和异种生物的作用。
T0803	Acetrizoic acid Urokon,醋碘苯酸,Opacaron,Acetrizoesaeure	Others	Others
	Acetrizoic acid (Urokon) 是小分子化合物，可用作显影剂。
T26637	Antipain dihydrochloride Antipain 2HCl,BDBM-32804,BDBM 32804, Antipain,BDBM32804	Protease	Proteases/Proteasome
	Antipain dihydrochloride (Antipain 2HCl) 是一种从 Actinomycetes 提取到的蛋白酶抑制剂，具有镇痛活性，抑制 X 射线诱导的人淋巴细胞染色体畸变。
T20112	Triphenyl bismuth NSC 465,三苯基铋,NSC-465,NSC465	Others	Others
	Triphenyl bismuth (NSC-465) 是一种添加剂，用于使生物医学树脂在 X 射线图像上可见，并可用作骨科骨水泥的不透射线剂。
T1554	Iohexol	Mitophagy; Autophagy	Autophagy
	Iohexol 是一种 X 射线造影剂，含有不同浓度的碘海醇，可用于多种成像的造影。
T20637	Diatrizoate meglumine Reno,Renografin,Renovist,泛影葡胺,Hypaque,Renocal,Sinografin	Others	Others
	Diatrizoate meglumine (Renocal) 是泛影酸盐的葡甲胺盐，它是一种有机的、碘化的、不透射线的 X 射线造影剂，用于放射诊断。
T1319	Sodium diatrizoate Diatrizoic acid sodium salt,Sodium amidotrizoate,Hypaque sodium,泛影酸钠,Diatrizoate sodium,amidotrizoate sodium,Triombrin	Apoptosis; Others	Apoptosis; Others
	Sodium diatrizoate是一种碘化不透射线 X 射线造影剂，在血管造影、尿路造影和放射造影中用作诊断辅助工具。它可通过钙失调诱导线粒体更新和氧化应激，激活细胞凋亡。
T1395	Diatrizoic Acid Diatrizoate,泛影酸,Amidotrizoic acid	Apoptosis; Others	Apoptosis; Others
	Diatrizoic Acid (Amidotrizoic acid) 是一种有机碘化不透射线 X 射线造影剂，用于放射诊断，具有对气道进行放射照相成像的潜力。它通过钙失调诱导线粒体更新和氧化应激，激活细胞凋亡。
T31035	CP 85339 CP-85339,CP85339,CP-85,339	Others	Others
	CP 85339 is an aspartic acid protease inhibitor for X-ray analysis of peptide-renin complexes.
T35133	WIN-68056 WIN 68056	Others	Others
	WIN-68056 is a wetting agent in x-ray contrast compositions.
T34971	Tyropanoate Sodium tyropanoate,Tyropanic acid,sodium tyropanoate	Others	Others
	Tyropanoate Sodium 是一种放射性造影剂，用于胆囊造影(x 线诊断胆结石)。
T85020	12-Bromododecanoic Acid NSC 660375,12-Bromolauric Acid,12-Bromo-C12:0,12-Bromododecanoate	Others	Others
	12-Bromododecanoic acid, a halogenated derivative of lauric acid, serves in the synthesis of clickable myristic acid derivatives and functions as a model fatty acid ligand for elucidating the X-ray crystal structure of bovine β-lactoglobulin-ligand complexes. This compound, at a concentration of 10 µg/ml, has been shown to diminish virion DNA in the culture supernatant of primary hepatocytes from a duckling model of hepatitis B virus (HBV) infection and exhibits inhibitory activity against HIV r...
T36096	Thiocoraline	Others	Others
	Thiocoraline is a depsipeptide and DNAbis-intercalator originally isolated fromMicromonosporawith antibacterial and anticancer activities.1,2It is active against the Gram-positive bacteriaS. aureus,B. subtilis, andM. luteus(MICs = 0.05, 0.05, and 0.03 μg/ml, respectively) but not Gram-negativeE. coli,K. pneumoniae, orP. aeruginosa(MICs = >100 μg/ml for all).1Thiocoraline inhibits RNA and DNA polymerase and thymidylate synthase (IC50s = 6, 6, and 15 μg/ml, respectively), as well as RNA and DNA sy...

化合物

Cat.No: T19376

Synonym: MP-328,碘佛醇

Target: Others

Cat.No: T1576

Synonym: SQ-13396,Niopam,Iopamiron,Iopamiro,碘帕醇,B-15000,Isovue

Target: Others

Acetrizoic acid

Cat.No: T0803

Synonym: Urokon,醋碘苯酸,Opacaron,Acetrizoesaeure

Target: Others

Antipain dihydrochloride

Cat.No: T26637

Synonym: Antipain 2HCl,BDBM-32804,BDBM 32804, Antipain,BDBM32804

Target: Protease

Triphenyl bismuth

Cat.No: T20112

Synonym: NSC 465,三苯基铋,NSC-465,NSC465

Target: Others

Cat.No: T1554

Target: Mitophagy, Autophagy

Diatrizoate meglumine

Cat.No: T20637

Synonym: Reno,Renografin,Renovist,泛影葡胺,Hypaque,Renocal,Sinografin

Target: Others

Sodium diatrizoate

Cat.No: T1319

Synonym: Diatrizoic acid sodium salt,Sodium amidotrizoate,Hypaque sodium,泛影酸钠,Diatrizoate sodium,amidotrizoate sodium,Triombrin

Target: Apoptosis, Others

Diatrizoic Acid

Cat.No: T1395

Synonym: Diatrizoate,泛影酸,Amidotrizoic acid

Target: Apoptosis, Others

Cat.No: T31035

Synonym: CP-85339,CP85339,CP-85,339

Target: Others

Cat.No: T35133

Synonym: WIN 68056

Target: Others

Tyropanoate Sodium

Cat.No: T34971

Synonym: tyropanoate,Tyropanic acid,sodium tyropanoate

Target: Others

12-Bromododecanoic Acid

Cat.No: T85020

Synonym: NSC 660375,12-Bromolauric Acid,12-Bromo-C12:0,12-Bromododecanoate

Target: Others

Cat.No: T36096

Target: Others

Species：

Expression System：

Tag：

Cat. No.	Product Name	Species	Expression System
TMPH-02315	XRCC5 Protein, Human, Recombinant (His & Myc) ATP-dependent DNA helicase 2 subunit 2,XRCC5,Ku86,N...	Human	E. coli
	Single-stranded DNA-dependent ATP-dependent helicase that plays a key role in DNA non-homologous end joining (NHEJ) by recruiting DNA-PK to DNA. Required for double-strand break repair and V(D)J recombination. Also has a role in chromosome translocation. The DNA helicase II complex binds preferentially to fork-like ends of double-stranded DNA in a cell cycle-dependent manner. It works in the 3'-5' direction. During NHEJ, the XRCC5-XRRC6 dimer performs the recognition step: it recognizes and bind...
TMPH-02314	XRCC5 Protein, Human, Recombinant (His & MBP) Nuclear factor IV,Lupus Ku autoantigen protein p86,ATP-depen...	Human	Baculovirus Insect Cells
	Single-stranded DNA-dependent ATP-dependent helicase that plays a key role in DNA non-homologous end joining (NHEJ) by recruiting DNA-PK to DNA. Required for double-strand break repair and V(D)J recombination. Also has a role in chromosome translocation. The DNA helicase II complex binds preferentially to fork-like ends of double-stranded DNA in a cell cycle-dependent manner. It works in the 3'-5' direction. During NHEJ, the XRCC5-XRRC6 dimer performs the recognition step: it recognizes and bind...
TMPY-02287	Ku70 & Ku80 Heterodimer Protein, Human, Recombinant (His) KARP1,XRCC5 & XRCC6,KUB2,KU80,KARP-1,Ku86,...	Human	Baculovirus Insect Cells
	X-ray repair cross-complementing protein 5, also known as 86 kDa subunit of Ku antigen, ATP-dependent DNA helicase 2 subunit 2, ATP-dependent DNA helicase II 8 kDa subunit, CTC box-binding factor 85 kDa subunit, DNA repair protein XRCC5, Lupus Ku autoantigen protein p86, TLAA and XRCC5, is a nucleus and chromosome which belongs to the ku8 family. XRCC5 is a single-stranded DNA-dependent ATP-dependent helicase. XRCC5 has a role in chromosome translocation. X-ray repair cross-complementing protein...
TMPY-00369	LY6D Protein, Human, Recombinant (mFc) E48,lymphocyte antigen 6 complex, locus D,Ly-6D	Human	HEK293 Cells
	LY6D (Lymphocyte Antigen 6 Family Member D) is a Protein Coding gene. It may act as a specification marker at the earliest stage specification of lymphocytes between B- and T-cell development. Marks the earliest stage of B-cell specification. The expression of LY6D is induced in MCF10A cells by X-ray irradiation. The induction of LY6D expression is triggered through a pathway regulated by ATM, CHK2, and p53. This method is a new Ab-directed proteomic strategy for the analysis of membrane protein...
TMPK-01158	Kallikrein 5/KLK5 Protein, Mouse, Recombinant (His) SCTE,KLKL2,KLK5,KLK-L2,Klnc,Kallikrein c	Mouse	HEK293 Cells
	The inhibition of kallikrein 5 (KLK5) has been identified as a potential strategy for treatment of the genetic skin disorder Netherton syndrome, in which loss-of-function mutations in the SPINK5 gene lead to down-regulation of the endogenous inhibitor LEKTI-1 and profound skin-barrier defects with severe allergic manifestations. To aid in the development of a medicine for this target, an X-ray crystallographic system was developed to facilitate fragment-guided chemistry and knowledge-based drug-...

重组蛋白

XRCC5 Protein, Human, Recombinant (His & Myc)

Cat.No: TMPH-02315

Species: Human

Expression System: E. coli

XRCC5 Protein, Human, Recombinant (His & MBP)

Cat.No: TMPH-02314

Species: Human

Expression System: Baculovirus Insect Cells

Ku70 & Ku80 Heterodimer Protein, Human, Recombinant (His)

Cat.No: TMPY-02287

Species: Human

Expression System: Baculovirus Insect Cells

LY6D Protein, Human, Recombinant (mFc)

Cat.No: TMPY-00369

Species: Human

Expression System: HEK293 Cells

Kallikrein 5/KLK5 Protein, Mouse, Recombinant (His)

Cat.No: TMPK-01158

Species: Mouse

Expression System: HEK293 Cells

Cat. No.	Product Name	Target	Signaling Pathways
T37847	Zonisamide-13C2,15N Zonisamide-13C2,15N
	Zonisamide-13C2,15N is intended for use as an internal standard for the quantification of zonisamide by GC- or LC-MS. Zonisamide is an antiepileptic agent.1 It selectively inhibits the repeated firing of sodium channels (IC50 = 2 μg/ml) in mouse embryo spinal cord neurons and inhibits spontaneous channel firing when used at concentrations greater than 10 μg/ml.2 In rat cerebral cortex neurons, zonisamide (1-1,000 μM) inhibits T-type calcium channels with a maximum reduction of 60% of the calcium...

同位素标记化合物

Zonisamide-13C2,15N

Cat.No: T37847

Synonym: Zonisamide-13C2,15N

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