Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T1485 |
Methotrexate
NCI-C04671,WR19039,Amethopterin,甲氨蝶呤,CL14377 |
Apoptosis; Dehydrogenase; DNA/RNA Synthesis; Antifolate; ADC Cytotoxin | Antibody-drug Conjugate/ADC Related; Apoptosis; Cell Cycle/Checkpoint; DNA Damage/DNA Repair; Metabolism |
Methotrexate (WR19039) 是一种叶酸类似物,一种二氢叶酸还原酶 DHFR 的抑制剂。Methotrexate 具有抗代谢、抗肿瘤和免疫抑制等活性,常用于类风湿关节炎和多种肿瘤的研究。 | |||
T65289 |
Methotrexate (hydrate)
|
Others | Others |
Methotrexate (hydrate) 是一种有用的有机化合物,可用于生命科学领域的相关研究。其产品编号为 T65289,CAS号为 133073-73-1。 | |||
T28027 |
Methotrexate monohydrate
Methotrexate hydrate |
Others; ADC Cytotoxin | Antibody-drug Conjugate/ADC Related; Others |
Methotrexate monohydrate is a DHhF reductase inhibitor. Methotrexate monohydrate increases T cell apoptosis, decreases T cell activation and suppresses cytokine production. | |||
T29965 |
Amethopterin
DL-Amethopterin |
Others | Others |
Amethopterin is a chemotherapy drug and immune system inhibitor used to treat cancers of the blood, bone, lung, breast, head, and neck. In addition, it can treat rheumatoid arthritis and psoriasis. |