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Targets Recommended: Others

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Cat. No. Product Name Target Signaling Pathways
T68536 WP-1034

Others Others
WP-1034 is a novel Jak-Stat inhibitor, which is active against AML blasts. WP-1034 effectively inhibited proliferation of OCIM2 cells and fresh AML samples. WP-1034 caused cell cycle arrest of OCIM2 cells in sub-Go phase. WP-1034 induced apoptosis of OCIM2 cells and that induction of apoptosis involved cleavage of caspase 3 and the DNA repair enzyme poly (adenosine diphosphate [ADP]-ribose) polymerase (PARP).

化合物

WP-1034
Cat.No: T68536
Synonym:
Target: Others
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