Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T23517 |
VUF 11207 fumarate
|
Others | Others |
ACKR3 (CXCR7) chemokine receptor agonist | |||
T13324 |
VUF11207 fumarate
|
CXCR; Arrestin | Autophagy; GPCR/G Protein; Immunology/Inflammation |
VUF11207 fumarate 是一种 CXCR7激动剂和高效CXCR7配体,pKi 为 8.1。它可诱导CXCR7的β-arrestin2募集和随后的内在化,pEC50分别为 8.8 和 7.9。 |