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Search Results for " tubulin inhibitor 6 "
Targets Recommended: Microtubule Associated

5

抑制剂 & 化合物

12

重组蛋白

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Cat. No. Product Name Target Signaling Pathways
T13224 Tubulin inhibitor 6

iHAP1

Microtubule Associated Cytoskeletal Signaling
Tubulin inhibitor 6 (iHAP1) 是一种微管蛋白抑制剂,抑制微管蛋白聚合,IC50为 0.87 μM。它抑制多种癌细胞系,抑制 K562 细胞生长,IC50为 840 nM。
T39139 PARP1-IN-6

PARP1-IN-6

Others Others
PARP1-IN-6 is a dual tubulin/PARP-1 inhibitor with IC 50 values of 0.94 and 0.48 μM, respectively.
T61532 Tubulin polymerization-IN-6

Others Others
Tubulin polymerization-IN-6 (compound 5f) is a potent inhibitor of tubulin polymerization, with an IC50 of 1.09 μM. It not only inhibits cell migration and tube formation but also has anti-angiogenic properties. Additionally, Tubulin polymerization-IN-6 has been found to effectively hinder tumor growth in HT29 xenograft Balb/c nude mice [1].
T74003 HDAC3/6-IN-2

Others Others
HDAC3/6-IN-2 (化合物 15) 是一种高效的HDAC6和HDAC3抑制剂,IC50值分别为0.368 μM和0.635 μM。此化合物不仅具备抗肿瘤活性,能够诱导癌细胞凋亡,同时通过降低HDAC6和HDAC3水平,与H3乙酰化和α-微管蛋白的上调有关。
T36199 AZD 1152 (hydrochloride)

Others Others
AZD 1152 is an orally bioavailable prodrug of AZD 1152-HQPA, a selective inhibitor of Aurora kinase B (IC50= 0.36 nM).1AZD 1152 is converted to AZD 1152-HQPA in plasma. Inhibition of Aurora B results in disruption of spindle checkpoint functions and chromosome alignment, resulting in inhibition of cytokinesis followed by apoptosis.2,3AZD 1152 inhibits tumor xenograft growthin vivo.4,5 1.Mortlock, A.A., Foote, K.M., Heron, N.M., et al.Discovery, synthesis, and in vivo activity of a new class of p...

化合物

Tubulin inhibitor 6
Cat.No: T13224
Synonym: iHAP1
Target: Microtubule Associated
PARP1-IN-6
Cat.No: T39139
Synonym: PARP1-IN-6
Target: Others
Tubulin polymerization-IN-6
Cat.No: T61532
Synonym:
Target: Others
HDAC3/6-IN-2
Cat.No: T74003
Synonym:
Target: Others
AZD 1152 (hydrochloride)
Cat.No: T36199
Synonym:
Target: Others
Cat. No. Product Name Species Expression System
TMPJ-00567 NCR1 Protein, Human, Recombinant (hFc)

hNKp46,Natural cytotoxicity triggering receptor 1,N...

Human HEK293 Cells
Natural cytotoxicity triggering receptor 1(NCR1) is a single-pass type I membrane protein .It contains 2 Ig-like (immunoglobulin-like) domains and belongs to the natural cytotoxicity receptor (NCR) family. The protein is a natural killer (NK) lymphocyte-activating receptor. It is involved in major aspects of NK immune function and shows a high degree of lineage specificity in blood and bone marrow.
TMPY-03128 LAIR1 Protein, Mouse, Recombinant (hFc)

leukocyte-associated immunoglobulin-like receptor 1,BB1152

Mouse HEK293 Cells
LAIR1 Protein, Mouse, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 39.6 kDa and the accession number is Q8BG84-6.
TMPJ-00827 Tau-D Protein, Human, Recombinant (His)

PHF-Tau,MAPTL,MAPT,Paired Helical Filament-Tau,Microtubule-A...

Human E. coli
Microtubule-Associated Protein TAU is abundantly expressed in neurons of the central nervous system and less commonly expressed elsewhere, but is also expressed at very low levels in CNS astrocytes and oligodendrocytes. Tau interacts with tubulin to stabilize microtubules and promotes tubulin assembly into microtubules. The C-terminus of TAU binds axonal microtubules while the N-terminus binds neural plasma membrane components, suggesting that tau acts as a linker protein. When tau is defective,...
TMPY-05798 VEGF145 Protein, Human, Recombinant

血管内皮生长因子,vascular endothelial growth factor A,VPF,MVCD1,VEGF...

Human HEK293 Cells
VEGF145 Protein, Human, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 16.92 kDa and the accession number is P15692-6.
TMPY-04277 CD45 Protein, Mouse, Recombinant (hFc)

Cd45,protein tyrosine phosphatase, receptor type, C,Ly-5,L-C...

Mouse HEK293 Cells
CD45 Protein, Mouse, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 71.7 kDa and the accession number is P06800-6.
TMPY-02600 NRG1 beta 1 Protein, Human, Recombinant (EGF Domain, hFc)

neuregulin 1,HRGA,NRG1 β1,HGL,MST131,MSTP131,HRG,ARIA,NDF,GG...

Human HEK293 Cells
NRG1 beta 1 Protein, Human, Recombinant (EGF Domain, hFc) is expressed in HEK293 mammalian cells with Fc tag. The predicted molecular weight is 36.7 kDa and the accession number is Q02297-6.
TMPY-02705 NRG1 beta 1 Protein, Human, Recombinant (hFc)

MSTP131,HRG1,NRG1-IT2,ARIA,HGL,SMDF,GGF,HRG,NDF,MST131,neure...

Human HEK293 Cells
NRG1 beta 1 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with Fc tag. The predicted molecular weight is 55.2 kDa and the accession number is Q02297-6.
TMPY-03010 NRG1 beta 1 Protein, Human, Recombinant

NDF,GGF,MSTP131,Neuregulin 1,MST131,ARIA,NRG1-IT2,SMDF,NRG1 ...

Human HEK293 Cells
NRG1 beta 1 Protein, Human, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 26.8 kDa and the accession number is Q02297-6.
TMPK-00614 NKp46/NCR1 Protein, Human, Recombinant (His)

NKp46,MAR-1,Ly94,NCR1,NKP46FLJ99094,CD335

Human HEK293 Cells
NKp46, along with NKp30 and NKp44, are activating receptors that have been collectively termed the natural cytotoxicity receptors (NCR).These receptors lack significant sequence homology to one another. They are expressed almost exclusively by NK cells and play a major role in triggering some of the key lytic activities of NK cells. NKp46/NCR1 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with N-His tag. The predicted molecular weight is 27.5 kDa and the accession numb...
TMPK-00615 NKp46/NCR1 Protein (Primary Amine Labeling), Human, Recombinant (His), Biotinylated

CD335,NCR1,NKp46,NKP46FLJ99094,Ly94,MAR-1

Human HEK293 Cells
NKp46, along with NKp30 and NKp44, are activating receptors that have been collectively termed the natural cytotoxicity receptors (NCR).These receptors lack significant sequence homology to one another. They are expressed almost exclusively by NK cells and play a major role in triggering some of the key lytic activities of NK cells. NKp46/NCR1 Protein (Primary Amine Labeling), Human, Recombinant (His), Biotinylated is expressed in HEK293 mammalian cells with N-His tag. The predicted molecular we...
TMPK-01364 SIRP alpha V6 Protein, Human, Recombinant (His & Avi), Biotinylated

SIRP α,MFR,SHPS1,SIRPA,BIT,SHPS-1,MYD-1,SIRP alpha,P84,CD172...

Human HEK293 Cells
Signal regulatory protein α (SIRPα) is a regulatory membrane glycoprotein from SIRP family expressed mainly by myeloid cells and also by stem cells or neurons.SIRPα acts as inhibitory receptor and interacts with a broadly expressed transmembrane protein CD47 also called the "don´t eat me" signal.Cancer cells highly expressed CD47 that activate SIRP α and inhibit macrophage-mediated destruction. SIRP alpha V6 Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian c...
TMPK-01358 SIRP alpha V6 Protein, Human, Recombinant (His & Avi)

P84,SIRPA,SIRP alpha,SHPS-1,MFR,BIT,MYD1,SIRP α V6,...

Human HEK293 Cells
Signal regulatory protein α (SIRPα) is a regulatory membrane glycoprotein from SIRP family expressed mainly by myeloid cells and also by stem cells or neurons.SIRPα acts as inhibitory receptor and interacts with a broadly expressed transmembrane protein CD47 also called the "don´t eat me" signal.Cancer cells highly expressed CD47 that activate SIRP α and inhibit macrophage-mediated destruction. SIRP alpha V6 Protein, Human, Recombinant (His & Avi) is expressed in HEK293 mammalian cells with C-Hi...

重组蛋白

NCR1 Protein, Human, Recombinant (hFc)
Cat.No: TMPJ-00567
Species: Human
Expression System: HEK293 Cells
LAIR1 Protein, Mouse, Recombinant (hFc)
Cat.No: TMPY-03128
Species: Mouse
Expression System: HEK293 Cells
Tau-D Protein, Human, Recombinant (His)
Cat.No: TMPJ-00827
Species: Human
Expression System: E. coli
VEGF145 Protein, Human, Recombinant
Cat.No: TMPY-05798
Species: Human
Expression System: HEK293 Cells
CD45 Protein, Mouse, Recombinant (hFc)
Cat.No: TMPY-04277
Species: Mouse
Expression System: HEK293 Cells
NRG1 beta 1 Protein, Human, Recombinant (EGF Domain, hFc)
Cat.No: TMPY-02600
Species: Human
Expression System: HEK293 Cells
NRG1 beta 1 Protein, Human, Recombinant (hFc)
Cat.No: TMPY-02705
Species: Human
Expression System: HEK293 Cells
NRG1 beta 1 Protein, Human, Recombinant
Cat.No: TMPY-03010
Species: Human
Expression System: HEK293 Cells
NKp46/NCR1 Protein, Human, Recombinant (His)
Cat.No: TMPK-00614
Species: Human
Expression System: HEK293 Cells
NKp46/NCR1 Protein (Primary Amine Labeling), Human, Recombinant (His), Biotinylated
Cat.No: TMPK-00615
Species: Human
Expression System: HEK293 Cells
SIRP alpha V6 Protein, Human, Recombinant (His & Avi), Biotinylated
Cat.No: TMPK-01364
Species: Human
Expression System: HEK293 Cells
SIRP alpha V6 Protein, Human, Recombinant (His & Avi)
Cat.No: TMPK-01358
Species: Human
Expression System: HEK293 Cells
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