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Search Results for " triiodothyronine "

Targets Recommended: Thyroid hormone receptor(THR) Endogenous Metabolite

7

抑制剂 & 化合物

3

天然产物

6

重组蛋白

3

同位素标记化合物

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Cat. No.	Product Name	Target	Signaling Pathways
T29011	Triiodothyronine Sulfate	Thyroid hormone receptor(THR); Endogenous Metabolite	Endocrinology/Hormones; Metabolism
	Triiodothyronine sulfate 是一种甲状腺激素三碘甲状腺原氨酸的主要代谢物，是一种甲状腺激素，与 β1 甲状腺激素受体结合并激活其特性。
T1669	Liothyronine sodium 3,3',5-Triiodo-L-thyronine sodium,Triostat,T3 Sodium salt,三碘代甲状腺素钠盐,Sodium L-3,3',5-triiodothyronine,Cytomel	Thyroid hormone receptor(THR)	Endocrinology/Hormones
	Liothyronine sodium (3,3',5-Triiodo-L-thyronine sodium) 是甲状腺激素，能够结合并激活 β1 甲状腺激素受体。
T1669L	Liothyronine HCl Triiodothyronine,L-T3,NSC 80203,Liothyronine,Liotironina,L-Liothyronine	Others	Others
	Liothyronine is a T3 thyroid hormone normally synthesized and secreted by the thyroid gland in much smaller quantities than thyroxine.
T7578	REVERSE T3 碘塞罗宁,3,3',5'-triiodo-L-thyronine	Thyroid hormone receptor(THR)	Endocrinology/Hormones
	Reverse T3 (3,3',5'-triiodo-L-thyronine) 是由甲状腺素原脱碘后产生的甲状腺激素。它可抑制由其它甲状腺激素类似物引起的新生大鼠心肌细胞中钠电流增加的作用。
T25411	Fenclofenac R 67408,Rx 67408,R67408,Flenac	Others	Others
	Fenclofenac is a non-steroidal anti-inflammatory agent that competitively supresses the binding of thyroxine(T4) and triiodothyronine (T3) by thyroxine-binding globulin(TBG).
T15699	L-Thyroxine sodium salt pentahydrate 左旋甲状腺素钠五水合物,Sodium levothyroxine pentahydrate,Levothyroxine,L-甲状腺素钠五水合物	Thyroid hormone receptor(THR)	Endocrinology/Hormones
	L-Thyroxine sodium salt pentahydrate (Levothyroxine) 是一种合成的甲状腺激素，用于甲状腺功能减退症的研究。
T35712	Debutyldronedarone hydrochloride SR35021 hydrochloride	Others	Others
	N-Desbutyl dronedarone is an active metabolite of the antiarrhythmic agent dronedarone .1,2,3It is formed from dronedarone by cytochrome P450s (CYPs) and monoamine oxidase (MAO) in human hepatocyte preparations.4N-Desbutyl dronedarone inhibits the binding of 3,3’,5-triiodo-L-thyronine to the thyroid hormone receptors TRα1and TRβ1(IC50s = 59 and 280 μM for the chicken and human receptors, respectively).1It inhibits CYP2J2-mediated formation of 14,15-EET from arachidonic acid and soluble epoxide h...

化合物

Triiodothyronine Sulfate

Cat.No: T29011

Target: Thyroid hormone receptor(THR), Endogenous Metabolite

Liothyronine sodium

Cat.No: T1669

Synonym: 3,3',5-Triiodo-L-thyronine sodium,Triostat,T3 Sodium salt,三碘代甲状腺素钠盐,Sodium L-3,3',5-triiodothyronine,Cytomel

Target: Thyroid hormone receptor(THR)

Liothyronine HCl

Cat.No: T1669L

Synonym: Triiodothyronine,L-T3,NSC 80203,Liothyronine,Liotironina,L-Liothyronine

Target: Others

Cat.No: T7578

Synonym: 碘塞罗宁,3,3',5'-triiodo-L-thyronine

Target: Thyroid hormone receptor(THR)

Cat.No: T25411

Synonym: R 67408,Rx 67408,R67408,Flenac

Target: Others

L-Thyroxine sodium salt pentahydrate

Cat.No: T15699

Synonym: 左旋甲状腺素钠五水合物,Sodium levothyroxine pentahydrate,Levothyroxine,L-甲状腺素钠五水合物

Target: Thyroid hormone receptor(THR)

Debutyldronedarone hydrochloride

Cat.No: T35712

Synonym: SR35021 hydrochloride

Target: Others

Cat. No.	Product Name	Target	Signaling Pathways
T1653	Liothyronine Tresitope,O-(4-Hydroxy-3-iodophenyl)-3,5-diiodo-L-tyrosine,碘噻罗宁,Triiodothyronine,三碘甲状腺原氨酸,L-3,3',5-Triiodothyronine,3,3',5-Triiodo-L-thyronine,Lyothyronine	Thyroid hormone receptor(THR); Endogenous Metabolite	Endocrinology/Hormones; Metabolism
	Liothyronine (Tresitope) 是一种人工合成的甲状腺激素，能够激活 β1 甲状腺激素受体 (TRβ1)。Liothyronine 能促进糖、蛋白质和脂肪三大物质的代谢，加速组织细胞的氧化过程，维持正常的基础代谢率，有利于机体的生长发育。
T0864	L-Thyroxine Levothyroxine,NSC 36397,L-甲状腺素,T4	Thyroid hormone receptor(THR); Endogenous Metabolite	Endocrinology/Hormones; Metabolism
	L-Thyroxine (NSC 36397) 是一种合成的甲状腺激素，用于甲状腺功能减退症的研究。在 DIO 酶作用下，L-Thyroxine (NSC 36397) 转化成具有生物特性的三碘甲状腺氨酸(T3)。
T13060	T3 Acyl glucuronide	Others	Others
	T3 Acyl glucuronide is the acyl glucuronide formation of triiodothyronine (T3). T3 Acyl glucuronide is an endogenous metabolite

天然产物

Cat.No: T1653

Synonym: Tresitope,O-(4-Hydroxy-3-iodophenyl)-3,5-diiodo-L-tyrosine,碘噻罗宁,Triiodothyronine,三碘甲状腺原氨酸,L-3,3',5-Triiodothyronine,3,3',5-Triiodo-L-thyronine,Lyothyronine

Target: Thyroid hormone receptor(THR), Endogenous Metabolite

Cat.No: T0864

Synonym: Levothyroxine,NSC 36397,L-甲状腺素,T4

Target: Thyroid hormone receptor(THR), Endogenous Metabolite

T3 Acyl glucuronide

Cat.No: T13060

Target: Others

Species：

Expression System：

Tag：

Cat. No.	Product Name	Species	Expression System
TMPY-02779	Thyroid peroxidase Protein, Human, Recombinant (S257A & P725T, His) thyroid peroxidase,MSA,TPX,TDH2A	Human	Baculovirus Insect Cells
	Thyroid peroxidase is a membrane-bound glycoprotein which belongs to the peroxidase family, XPO subfamily. It contains 1 EGF-like domain and 1 Sushi (CCP/SCR) domain. Thyroid Peroxidase represents one of the main autoantigenic targets in autoimmune thyroid disease of humans. It used to be taken as the formerly so-called `microsomal antigen` several years ago. As an integral membrane glycoprotein it is restricted to the apical plasma membrane of the follicular epithelial cells and comprises two i...
TMPH-02204	THRB Protein, Human, Recombinant (His & SUMO) c-erbA-beta,THRB,Thyroid hormone receptor beta,c-erbA-2,Nucl...	Human	E. coli
	Nuclear hormone receptor that can act as a repressor or activator of transcription. High affinity receptor for thyroid hormones, including triiodothyronine and thyroxine.
TMPH-03377	SULT1B1 Protein, Rat, Recombinant (His & Myc & SUMO) DOPA/tyrosine sulfotransferase,Sult1b1,Sulfotransferase fami...	Rat	E. coli
	Sulfotransferase that utilizes 3'-phospho-5'-adenylyl sulfate (PAPS) as sulfonate donor to catalyze the sulfate conjugation of dopamine, small phenols such as 1-naphthol and p-nitrophenol and thyroid hormones, including 3,3'-diiodothyronine, triidothyronine (T3) and reverse triiodothyronine (rT3). SULT1B1 Protein, Rat, Recombinant (His & Myc & SUMO) is expressed in E. coli expression system with N-10xHis-SUMO and C-Myc tag. The predicted molecular weight is 54.8 kDa and the accession number is P...
TMPH-02203	THRA Protein, Human, Recombinant (His) c-erbA-1,c-erbA-alpha,THRA,Thyroid hormone receptor alpha,V-...	Human	E. coli
	Nuclear hormone receptor that can act as a repressor or activator of transcription. High affinity receptor for thyroid hormones, including triiodothyronine and thyroxine.; Does not bind thyroid hormone and functions as a weak dominant negative inhibitor of thyroid hormone action. THRA Protein, Human, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 58.9 kDa and the accession number is P10827.
TMPH-03385	Thyroglobulin Protein, Rat, Recombinant (His & SUMO) Tg,Thyroglobulin	Rat	E. coli
	Acts as a substrate for the production of iodinated thyroid hormones thyroxine (T4) and triiodothyronine (T3). The synthesis of T3 and T4 involves iodination of selected tyrosine residues of TG/thyroglobulin followed by their oxidative coupling. Following TG re-internalization and lysosomal-mediated proteolysis, T3 and T4 are released from the polypeptide backbone leading to their secretion into the bloodstream. One dimer produces 7 thyroid hormone molecules. Thyroglobulin Protein, Rat, Recombin...
TMPY-01617	SULT1B1 Protein, Human, Recombinant (His) sulfotransferase family, cytosolic, 1B, member 1,SULT1B2,ST1...	Human	E. coli
	Sulfotransferase family cytosolic 1B member 1, also known as Sulfotransferase 1B1, Sulfotransferase 1B2, Thyroid hormone sulfotransferase, SULT1B1 and ST1B2, is a cytoplasm protein that belongs to the sulfotransferase 1 family. Sulfotransferase enzymes catalyze the sulfate conjugation of many hormones, neurotransmitters, drugs, and xenobiotic compounds. These cytosolic enzymes are different in their tissue distributions and substrate specificities. SULT1B1 is highly expressed in the liver, perip...

重组蛋白

Thyroid peroxidase Protein, Human, Recombinant (S257A & P725T, His)

Cat.No: TMPY-02779

Species: Human

Expression System: Baculovirus Insect Cells

THRB Protein, Human, Recombinant (His & SUMO)

Cat.No: TMPH-02204

Species: Human

Expression System: E. coli

SULT1B1 Protein, Rat, Recombinant (His & Myc & SUMO)

Cat.No: TMPH-03377

Species: Rat

Expression System: E. coli

THRA Protein, Human, Recombinant (His)

Cat.No: TMPH-02203

Species: Human

Expression System: E. coli

Thyroglobulin Protein, Rat, Recombinant (His & SUMO)

Cat.No: TMPH-03385

Species: Rat

Expression System: E. coli

SULT1B1 Protein, Human, Recombinant (His)

Cat.No: TMPY-01617

Species: Human

Expression System: E. coli

Cat. No.	Product Name	Target	Signaling Pathways
TMID-0105	Triiodothyronine-13C6 hydrochloridehydrochloride 3,3',5-Triiodothyronine-(tyrosine ring-13C6)
	3,3',5-Triiodothyronine-(tyrosine ring-13C6) hydrochloride 是 3,3',5-Triiodothyronine hydrochloride 的 13C 的标记化合物。
TMID-0106	3,3',5-Triiodothyronine-(tyrosine ring-13C6) T3-13C6
	3,3',5-Triiodothyronine-(tyrosine ring-13C6) 是 3,3',5-Triiodothyronine 的 13C 的标记化合物。3,3',5-Triiodothyronine 的 CAS 号为 5817-39-0。
TMID-0104	L-Thyroxine-13C6
	L-Thyroxine-13C6 是 L-Thyroxine 的 13C 的标记化合物。L-Thyroxine 的 CAS 号为 51-48-9。L-Thyroxine (T4)是一种合成的甲状腺激素，用于甲状腺功能减退症的研究。在DIO 酶作用下， L-Thyroxine (T4)转化成具有生物特性的三碘甲状腺氨酸 (T3)。

同位素标记化合物

Triiodothyronine-13C6 hydrochloridehydrochloride

Cat.No: TMID-0105

Synonym: 3,3',5-Triiodothyronine-(tyrosine ring-13C6)

3,3',5-Triiodothyronine-(tyrosine ring-13C6)

Cat.No: TMID-0106

Synonym: T3-13C6

L-Thyroxine-13C6

Cat.No: TMID-0104

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