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Search Results for " tranylcypromine "

Targets Recommended: Monoamine Oxidase

抑制剂 & 化合物

同位素标记化合物

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Cat. No.	Product Name	Target	Signaling Pathways
T79914	Tranylcypromine SKF 385	Monoamine Oxidase	Neuroscience
	Tranylcypromine (SKF 385)为一种高效的单胺氧化酶抑制剂。
T7942	Tranylcypromine hemisulfate Tranylcypromine Sulfate,Tranylcypromine (hemisulfate),反苯环丙胺半硫酸盐	Histone Demethylase; MAO; Monoamine Oxidase	Chromatin/Epigenetic; Metabolism; Neuroscience
	Tranylcypromine hemisulfate (Tranylcypromine Sulfate) 是单胺氧化酶(MAO) 和赖氨酸特异性去甲基化酶 1 (LSD1) 的抑制剂，可用于研究抑郁症和子宫内膜异位症。
T1025	Tranylcypromine (2-PCPA) hydrochloride 反苯环丙胺盐酸盐,Tranylcypromine (2-PCPA) HCl,SKF-385 HCl	Histone Demethylase; MAO	Chromatin/Epigenetic; Metabolism; Neuroscience
	Tranylcypromine (2-PCPA) hydrochloride (SKF-385 HCl) 是一种单胺氧化酶抑制剂，对治疗重度抑郁症、心境恶劣障碍和非典型抑郁症有效。
T71826	(1S,2R)-Tranylcypromine hydrochloride (1S,2R)-SKF 385 hydrochloride	Others	Others
	(1S,2R)-Tranylcypromine ((1S,2R)-SKF 385) hydrochloride 是一种有效的抗抑郁 (antidepressant) 剂。(1S,2R)-Tranylcypromine hydrochloride 对 MAO 和 LSD1有抑制作用。
T39799	S2157 S2157	Others	Others
	S2157, a potent N-alkylated tranylcypromine (TCP) derivative lysine-specific demethylase 1 (LSD1) inhibitor, enhances H3K9 methylation and concurrently reduces H3K27 acetylation at super-enhancer sites. This compound triggers apoptosis in TCP-resistant T-cell acute lymphoblastic leukemia (T-ALL) cells by inhibiting NOTCH3 and TAL1 gene expression. Moreover, S2157 is capable of crossing the blood-brain barrier, effectively eliminating central nervous system (CNS) leukemia in mice models implanted...
T39800	S2116	Others	Others
	S2116 is a powerful inhibitor of lysine-specific demethylase 1 (LSD1), and it is a derivative of N-alkylated tranylcypromine (TCP). S2116 exhibits its inhibitory effects by increasing H3K9 methylation and inducing reciprocal H3K27 deacetylation at super-enhancer regions. In TCP-resistant T-cell acute lymphoblastic leukemia (T-ALL) cells, S2116 triggers apoptosis by repressing the transcription of NOTCH3 and TAL1 genes. Furthermore, S2116 demonstrates significant growth retardation of T-ALL cells...

化合物

Tranylcypromine

Cat.No: T79914

Synonym: SKF 385

Target: Monoamine Oxidase

Tranylcypromine hemisulfate

Cat.No: T7942

Synonym: Tranylcypromine Sulfate,Tranylcypromine (hemisulfate),反苯环丙胺半硫酸盐

Target: Histone Demethylase, MAO, Monoamine Oxidase

Tranylcypromine (2-PCPA) hydrochloride

Cat.No: T1025

Synonym: 反苯环丙胺盐酸盐,Tranylcypromine (2-PCPA) HCl,SKF-385 HCl

Target: Histone Demethylase, MAO

(1S,2R)-Tranylcypromine hydrochloride

Cat.No: T71826

Synonym: (1S,2R)-SKF 385 hydrochloride

Cat. No.	Product Name	Target	Signaling Pathways
T12701	(rel)-Tranylcypromine D5 hydrochloride 2-Phenylcyclopropylamine D5 hydrochloride	Histone Demethylase	Chromatin/Epigenetic
	(rel)-Tranylcypromine D5 hydrochloride is a deuterium labeled (rel)-Tranylcypromine hydrochloride. (rel)-Tranylcypromine hydrochloride is an irreversible, nonselective inhibitor of monoamine oxidase (MAO) used in the treatment of depression.