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Cat. No. | Product Name | ||
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L7600 | 趋化因子抑制剂库 | 59 compounds | |
59 种趋化因子或其受体抑制剂的独特集合,可用于高通量筛选和高内涵筛选; |
Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
TP1174 |
Endothelin-2 (49-69), human
Human endothelin-2,Endothelin-2, human,Endothelin-2 (human, canine),人内皮素2 |
Others | Others |
Endothelin-2 (49-69), human (Human endothelin-2) 是一种由 21 个氨基酸组成的血管活性肽。它可与 G 蛋白连接的跨膜受体,ET-RA 和ET-RB 结合。 | |||
T73873 |
c-di-AMP disodium
|
Others | Others |
c-di-AMP (Cyclic diadenylate) sodium 作为一种STING 激动剂,通过结合STING 激活TBK3-IRF3 信号途径,引发I 型 IFN 和 TNF 产生,兼具细菌第二信使功能,在革兰氏阳性细菌中调控细胞生长、存活及毒力,并影响宿主免疫反应。此外,作为有效的粘膜佐剂,它能刺激体液和细胞反应。 | |||
T83851 |
Tat-QFNP12 TFA
|
||
Tat-QFNP12 是一种含有转录激活因子 (Tat) 跨膜结构域和抑制N-Myc下游调节基因2 (NDRG2) 与蛋白磷酸酶Mg2+/Mn2+依赖性1A (PPM1A) 蛋白-蛋白相互作用的肽。在以20 mg/kg剂量给药的内脑血管穿刺诱导的小鼠蛛网膜下腔出血模型中,它能减少由基质金属蛋白酶-9 (MMP-9) 浓度增高引起的血脑屏障内皮紧密连接的损失,减轻脑水肿,并且提高自发活动及肢体运动的对称性。 |
Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T75540 |
Ipomoeassin F
|
Others | Others |
Ipomoeassin F 是一种高效且具有选择性的内质网(ER)蛋白转位抑制剂,它通过作用于ER膜上的Sec61复合物(Sec61α)的成孔亚基来实现其功能。此化合物能特异性抑制SARS-CoV-2蛋白在ER膜上的转位,同时阻碍分泌蛋白和I型跨膜蛋白(TMP)的ER转运,但对III型TMP的转运不产生影响。 |
Cat. No. | Product Name | Species | Expression System |
---|---|---|---|
TMPY-03578 |
FLRT2 Protein, Mouse, Recombinant (His)
FLRT2,fibronectin leucine rich transmembrane |
Mouse | HEK293 Cells |
FLRT2 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 57.6 kDa and the accession number is Q8BLU0. | |||
TMPJ-01404 |
TMX2 Protein, Human, Recombinant (His)
Cell proliferation-inducing gene 26 protein |
Human | E. coli |
TMX2 is a single-pass type I membrane protein and contains 1 thioredoxin domain. Thioredoxin plays an important role in various cellular processes through redox regulation. The Molecular Cloning and characterization of one member of the thioredoxin superfamily, designated as TMX2.The TMX2 cDNA consists of 1644 nucleotides and contains an open reading frame encoding a protein of 372 amino acids with a predicted molecular mass of 42.5 kDa and an isoelectric point of 8.94. The TMX2 protein may pos... | |||
TMPY-02048 |
FLRT2 Protein, Human, Recombinant (His)
UNQ232/PRO265,fibronectin leucine... |
Human | HEK293 Cells |
FLRT2 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 57.7 kDa and the accession number is O43155. | |||
TMPJ-01398 |
ITM2B Protein, Human, Recombinant (His)
Transmembrane Protein BRI,Protein... |
Human | HEK293 Cells |
Integral Membrane Protein 2B (ITM2B) is expressed in the Golgi and on the cell surface. ITM2B forms homodimer through disulfide-linked interaction with SPPL2A, SPPL2B and APP. ITM2B is expressed in brain and the other tissues. Defects in ITM2B cause cerebral amyloid angiopathy ITM2B-related type 1(CAA-ITM2B1) and amyloid angiopathy ITM2B-related type 2(CAA-ITM2B2). CAA-ITM2B1 is characterized by amyloid deposition in the walls of cerebral blood vessels and neurodegeneration in the central nervou... | |||
TMPJ-01238 |
VSTM2A Protein, Human, Recombinant (His)
VSTM2,V-set and transmembrane domain-conta... |
Human | HEK293 Cells |
VSTM2A, also called VSTM2, is short for V-set and transmembrane domain-containing protein 2A. It is a 236 aa. protein which can be departed into two parts. The first 24 aa. is a signal peptide, and the last is a V-set and transmembrane domain-containing protein 2A. There is a natural variant location which is E84K. | |||
TMPH-02572 |
TMEM2 Protein, Mouse, Recombinant (His)
Transmembrane protein 2,Cell migr... |
Mouse | E. coli |
Cell surface hyaluronidase that mediates the initial cleavage of extracellular high-molecular-weight hyaluronan into intermediate-size hyaluronan of approximately 5 kDa fragments. Acts as a regulator of angiogenesis and heart morphogenesis by mediating degradation of extracellular hyaluronan, thereby regulating VEGF signaling. Is very specific to hyaluronan; not able to cleave chondroitin sulfate or dermatan sulfate. | |||
TMPH-02847 |
CNPY2 Protein, Mouse, Recombinant (His & Myc)
MIR-interacting saposin-like protein,Tmem4,Tran... |
Mouse | E. coli |
Positive regulator of neurite outgrowth by stabilizing myosin regulatory light chain (MRLC). It prevents MIR-mediated MRLC ubiquitination and its subsequent proteasomal degradation. | |||
TMPH-02214 |
Tomoregulin-1 Protein, Human, Recombinant (His)
TMEFF2,Tomoregulin-2,Transmembrane |
Human | HEK293 Cells |
May be a survival factor for hippocampal and mesencephalic neurons. The shedded form up-regulates cancer cell proliferation, probably by promoting ERK1/2 phosphorylation. | |||
TMPJ-01252 |
CLEC2D Protein, Mouse, Recombinant (His)
Clec2d,Clr-b,Clrb,Ocil,Osteoclast inhibitory lectin... |
Mouse | HEK293 Cells |
C-type lectin domain family 2, member D (CLEC2D) is implicated in the immune response. Sensing tissue damage is an ancient function of immune cells that is central to the regulation of inflammation, tissue repair, and immunity. The C-type lectin receptor Clec2d as a sensor of cell death, which directly detects histones released during necrosis and thus contributes to inflammation and immunopathology. The Clec2d pathway may also be exploited to favor a pro-inflammatory anti-tumor response. And tu... | |||
TMPJ-00348 |
CD316 Protein, Human, Recombinant (hFc)
KCT-4,EWI2,CD81P3,CD316,IGSF8,Glu-Trp-Ile EWI Motif... |
Human | HEK293 Cells |
Immunoglobulin Superfamily Member 8 (IGSF8) is a single-pass membrane protein. IGSF8 contains four Ig-like C2 type domains. The Ig-like C2-type domains 3 and 4 are required for interactions with CD81. IGSF8 may regulate proliferation and differentiation of keratinocytes. IGSF8 may participate in the regulation of neurite outgrowth and maintenance of the neural network in the adult brain. It also may play a role on integrin-dependent morphology and motility functions. | |||
TMPH-02023 |
Renin receptor Protein, Human, Recombinant (His)
Vacuolar ATP synthase membrane sector-associated protein... |
Human | E. coli |
Renin receptor Protein, Human, Recombinant (His) is expressed in E. coli. | |||
TMPK-01207 |
DLL3 Protein, Human, Recombinant (His & Avi), Biotinylated
Pudgy,δ3,SCDO1δ3,Delta3,SCDO1delta3,SCDO1,DLL3 |
Human | HEK293 Cells |
Delta-like protein 3 (DLL3) is a transmembrane protein that belongs to the Delta/Serrate/Lag-2 (DSL) family of Notch ligands. DLL3 inhibits primary neurogenesis. May be required to divert neurons along a specific differentiation pathway. Plays a role in the formation of somite boundaries during segmentation of the paraxial mesoderm (By similarity). DLL3 Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight ... | |||
TMPY-02700 |
BCL2 Protein, Human, Recombinant (His)
Bcl-2,PPP1R50,B-cell CLL/lymphoma 2 |
Human | E. coli |
BCL2 (B-cell leukemia/lymphoma 2, N-Histidine-tagged), also known as Bcl-2, belongs to the Bcl-2 family. Bcl-2 family proteins regulate and contribute to programmed cell death or apoptosis. It is a large protein family and all members contain at least one of four BH (bcl-2 homology) domains. Certain members such as Bcl-2, Bcl-xl and Mcl1 are anti-apoptotic, whilst others are pro-apoptotic. Most Bcl-2 family members contain a C-terminal transmembrane domain that functions to target these proteins... | |||
TMPY-01964 |
CD16a Protein, Human, Recombinant (F176V, His)
FCGRIII,Fc gamma RIIIa,FCR-10,FCRIII,FCRIIIA,FCGR3,CD16A,Fc... |
Human | HEK293 Cells |
The Fc receptor with low affinity for IgG (FCGR3, or CD16) is encoded by 2 nearly identical genes, FCGR3A and FCGR3B, resulting in tissue-specific expression of alternative membrane-anchored isoforms. FCGR3A, it is also known as CD16a, encodes a transmembrane protein expressed on activated monocytes/macrophages, natural killer (NK) cells, and a subset of T cells. CD16a / FCGR3A is a receptor expressed on NK cells that facilitates antibody dependent cellular cytotoxicity (ADCC) by binding to the... | |||
TMPY-04202 |
Tomoregulin-1 Protein, Mouse, Recombinant (hFc)
M7365,transmembrane protein with EGF-like ... |
Mouse | HEK293 Cells |
TMEFF1 is a novel transmembrane protein, containing two follisatin domains and an epidermal growth factor-like region. The ectopic expression of TMEFF1 in brain cancer cells resulted in their growth inhibition. That TMEFF1 may behave as a tumor suppressor gene in brain cancers. TMEFF1 and TMEFF2 are putative transmembrane proteins comprised of one epidermal growth factor (EGF)-like domain and two follistatin-like domains. Both TMEFF1 and TMEFF2 are predominantly expressed in the brain. Tomoregul... | |||
TMPK-00679 |
EpCAM/TROP1 Protein, Cynomolgus/Rhesus macaque, Recombinant
EpCAM,ACSTD1,ESA,MK1,EGP-2,EGP,MOC31,HNPCC8,EGP40,T... |
Cynomolgus,Rhesus | HEK293 Cells |
Epithelial Cellular Adhesion Molecule (EpCAM), also known as KS1/4, gp40, GA733-2, 17-1A, and TROP‑1, is a 40 kDa transmembrane glycoprotein that consists of a 242 amino acid (aa) extracellular domain with two EGF‑like repeats, a 23 aa transmembrane segment, and a 26 aa cytoplasmic domain. EpCAM/TROP1 Protein, Cynomolgus/Rhesus macaque, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 27.38 kDa and the accession number is Q1WER1. | |||
TMPK-01167 |
TEM7R/PLXDC2 Protein, Mouse, Recombinant (His)
PLXDC2,TEM7R |
Mouse | HEK293 Cells |
Plexin domain containing 2 (PLXDC2), a cell surface transmembrane protein receptor for pigment epithelium derived factor, is expressed in many tissues including the eye. Plxdc2 is a type I transmembrane protein with some homology to nidogen and to plexins. It is expressed in a highly discrete and dynamic pattern in the developing nervous system, with prominent expression in various patterning centres. TEM7R/PLXDC2 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with C-Hi... | |||
TMPY-02285 |
Influenza A H1N1 (A/Puerto Rico/8/34/Mount Sinai) Non-structural/NS2 Protein
NS2 Protein |
H1N1 | E. coli |
Non-structural protein 2 (NS2) plays a crucial role in the hepatitis C virus (HCV) assembly. NS2 was predicted to be composed of three transmembrane (TM) segments. Hepatitis C virus (HCV) nonstructural protein 2 (NS2) is a hydrophobic, transmembrane protein that is required not only for NS2-NS3 cleavage but also for infectious virus production.NS2 protein is essential for hepatitis C virus (HCV) replication. NS2 protein was expressed and purified. Aptamers against NS2 protein were raised and ant... | |||
TMPK-00206 |
EpCAM/TROP1 Protein, Human, Recombinant (aa 24-265, hFc)
ESA,TACSTD1,EGP-2,TROP1,EpCAM,EGP314,MOC31,DIAR5,CD... |
Human | HEK293 Cells |
Epithelial Cellular Adhesion Molecule (EpCAM), also known as KS1/4, gp40, GA733-2, 17-1A, and TROP‑1, is a 40 kDa transmembrane glycoprotein that consists of a 242 amino acid (aa) extracellular domain with two EGF‑like repeats, a 23 aa transmembrane segment, and a 26 aa cytoplasmic domain. EpCAM/TROP1 Protein, Human, Recombinant (aa 24-265, hFc) is expressed in HEK293 mammalian cells with C-hFc tag. The predicted molecular weight is 54.2 kDa and the accession number is P16422. | |||
TMPK-01055 |
TEM7R/PLXDC2 Protein, Human, Recombinant (His)
PLXDC2,TEM7R |
Human | HEK293 Cells |
Plexin domain containing 2 (PLXDC2), a cell surface transmembrane protein receptor for pigment epithelium derived factor, is expressed in many tissues including the eye. Plxdc2 is a type I transmembrane protein with some homology to nidogen and to plexins. It is expressed in a highly discrete and dynamic pattern in the developing nervous system, with prominent expression in various patterning centres. TEM7R/PLXDC2 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with C-Hi... | |||
TMPY-01117 |
MRAP Protein, Human, Recombinant (hFc)
FALP,FGD2,melanocortin 2 receptor accessor... |
Human | HEK293 Cells |
MRAP (Melanocortin 2 Receptor Accessory Protein) is a Protein Coding gene. This gene encodes a melanocortin receptor-interacting protein. It belongs to the MRAP family. MRAP, which contains a single transmembrane domain, has a unique structure, an antiparallel homodimer. MRAP is a single transmembrane domain accessory protein and a critical component of the hypothamo pituitary-adrenal axis. MRAP is highly expressed in the adrenal gland and is essential for adrenocorticotropin hormone (ACTH) rece... | |||
TMPK-00507 |
TREM2 Protein, Cynomolgus, Recombinant (His)
TREM2,Trem2a,PLOSL2,TREM-2 |
Cynomolgus | HEK293 Cells |
TREM-2 (Triggering Receptor Expressed on Myeloid cells-2) is a 35 kDa type I transmembrane member of the TREM family and Ig superfamily. Mature human TREM-2 consists of a 156 amino acid (aa) extracellular domain (ECD) with one V-type Ig-like domain, a 21 aa transmembrane (TM) domain, and a 35 aa cytoplasmic tail. TREM-2 forms a receptor signaling complex with TYROBP which mediates signaling and cell activation following ligand binding (PubMed:10799849). Acts as a receptor for amyloid-beta prote... | |||
TMPK-00207 |
EpCAM/TROP1 Protein, Human, Recombinant (aa 24-265, His)
DIAR5,MOC31,EGP,MK1,HNPCC8,EGP314,ESA,MIC18,TROP1,EGP40,EpCA... |
Human | HEK293 Cells |
Epithelial Cellular Adhesion Molecule (EpCAM), also known as KS1/4, gp40, GA733-2, 17-1A, and TROP‑1, is a 40 kDa transmembrane glycoprotein that consists of a 242 amino acid (aa) extracellular domain with two EGF‑like repeats, a 23 aa transmembrane segment, and a 26 aa cytoplasmic domain. EpCAM/TROP1 Protein, Human, Recombinant (aa 24-265, His) is expressed in HEK293 mammalian cells with C-His tag. The predicted molecular weight is 28.2 kDa and the accession number is P16422. | |||
TMPK-01111 |
LILRB1/CD85j/ILT2 Domain1 & 2 Protein, Human, Recombinant (His)
CD85J,XXbac-BCX85G21.4,LILRB1,ILT2,ILT... |
Human | HEK293 Cells |
LILRB1, also known as CD85j and IL-T2, is a 110 kDa transmembrane glycoprotein in the LILR immunoregulatory protein family. Mature human LILRB1 consists of a 438 amino acid (aa) extracellular domain (ECD) with 4 tandem Ig-like domains, a 21 aa transmembrane segment, and a 168 aa cytoplasmic domain with 4 inhibitory ITIM motifs.LILRB1 is a receptor for class I MHC antigens. LILRB1/CD85j/ILT2 Domain1 & 2 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with C-His tag. The p... | |||
TMPK-00680 |
EpCAM/TROP1 Protein, Cynomolgus/Rhesus macaque, Recombinant (His)
EGP40,EGP314,CD326,EGP,KSA,HNPCC8,ESA,DIAR5,MOC31,T... |
Cynomolgus,Rhesus | HEK293 Cells |
Epithelial Cellular Adhesion Molecule (EpCAM), also known as KS1/4, gp40, GA733-2, 17-1A, and TROP‑1, is a 40 kDa transmembrane glycoprotein that consists of a 242 amino acid (aa) extracellular domain with two EGF‑like repeats, a 23 aa transmembrane segment, and a 26 aa cytoplasmic domain. EpCAM/TROP1 Protein, Cynomolgus/Rhesus macaque, Recombinant (His) is expressed in HEK293 mammalian cells with C-His tag. The predicted molecular weight is 28.5 kDa and the accession number is Q1WER1. | |||
TMPK-00986 |
IL-2 R gamma/CD132 Protein, Cynomolgus, Recombinant (His)
SCIDX1,IL2RG,gammaC,γC,CIDX,IL-2 R γ/CD13<... |
Cynomolgus | HEK293 Cells |
The gamma chain of the high affinity functional human IL-2 receptor complex belongs to the hematopoietin receptor family. IL-2 R gamma is a 369 amino acid residue protein consisting of a 22 residue signal sequence, a 232 residue extracellular domain, a 29 residue transmembrane domain and an 86 residue cytoplasmic domain. Although IL-2 R gamma by itself does not bind IL-2 with any appreciable affinity, it is required for IL-2 receptor signaling. IL-2 R gamma/CD132 Protein, Cynomolgus, Recombinant... | |||
TMPK-00205 |
EpCAM/TROP1 Protein, Human, Recombinant (aa 24-265, His & Avi), Biotinylated
EGP40,TROP1,EGP314,MIC18,DIAR5,ESA,KSA,TACST-1,EpCAM,EGP,MOC... |
Human | HEK293 Cells |
Epithelial Cellular Adhesion Molecule (EpCAM), also known as KS1/4, gp40, GA733-2, 17-1A, and TROP‑1, is a 40 kDa transmembrane glycoprotein that consists of a 242 amino acid (aa) extracellular domain with two EGF‑like repeats, a 23 aa transmembrane segment, and a 26 aa cytoplasmic domain. EpCAM/TROP1 Protein, Human, Recombinant (aa 24-265, His & Avi), Biotinylated is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 30.1 kDa and the accession number is P1... | |||
TMPK-01208 |
DLL3 Protein, Human, Recombinant (His & Flag)
Pudgy,SCDO1,DLL3,Delta3,SCDO1δ3,δ3,SCDO1delta3 |
Human | HEK293 Cells |
Delta-like protein 3 (DLL3) is a transmembrane protein that belongs to the Delta/Serrate/Lag-2 (DSL) family of Notch ligands. DLL3 inhibits primary neurogenesis. May be required to divert neurons along a specific differentiation pathway. Plays a role in the formation of somite boundaries during segmentation of the paraxial mesoderm (By similarity). DLL3 Protein, Human, Recombinant (His & Flag) is expressed in HEK293 mammalian cells with N-His-Flag tag. The predicted molecular weight is 22.30 kDa... | |||
TMPK-00640 |
DLL3 Protein, Rhesus macaque, Recombinant (His)
SCDO1delta3,Pudgy,δ3,SCDO1,SCDO1δ3,DLL3,Delta3 |
Rhesus | HEK293 Cells |
Delta-like protein 3 (DLL3) is a transmembrane protein that belongs to the Delta/Serrate/Lag-2 (DSL) family of Notch ligands. DLL3 inhibits primary neurogenesis. May be required to divert neurons along a specific differentiation pathway. Plays a role in the formation of somite boundaries during segmentation of the paraxial mesoderm (By similarity). DLL3 Protein, Rhesus macaque, Recombinant (His) is expressed in HEK293 mammalian cells with N-His tag. The predicted molecular weight is 51 kDa and t... | |||
TMPK-00219 |
MICA Protein, Human, Recombinant (His & Avi), Biotinylated
MICA,MGC21250,DAMA-345G11.2,MGC11... |
Human | HEK293 Cells |
TMICA (MHC class I chain-related gene A) is a transmembrane glycoprotein that functions as a ligand for human NKG2D. A closely related protein, MICB, shares 85% amino acid identity with MICA. These proteins are distantly related to the MHC class I proteins. They possess three extracellular Ig‑like domains, but they have no capacity to bind peptide or interact with beta 2-microglobulin. | |||
TMPK-00059 |
CD94 Protein, Human, Recombinant (His & Avi), Biotinylated
NK cell receptor,CD94,KP43,KLRD1 |
Human | HEK293 Cells |
CD94 is an approximately 25 kDa type 2 transmembrane protein that plays an important role in regulating natural killer (NK) cell activation.CD94 plays a role as a receptor for the recognition of MHC class I HLA-E molecules by NK cells and some cytotoxic T-cells. CD94 Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with N-His-Avi tag. The predicted molecular weight is 19.8 kDa and the accession number is Q13241-1. | |||
TMPK-01209 |
DLL3 Protein, Human, Recombinant (His)
Pudgy,SCDO1delta3,DLL3,SCDO1δ3,SCDO1,δ3,Delta3 |
Human | HEK293 Cells |
Delta-like protein 3 (DLL3) is a transmembrane protein that belongs to the Delta/Serrate/Lag-2 (DSL) family of Notch ligands. DLL3 inhibits primary neurogenesis. May be required to divert neurons along a specific differentiation pathway. Plays a role in the formation of somite boundaries during segmentation of the paraxial mesoderm (By similarity). DLL3 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with N-His tag. The predicted molecular weight is 50.4 kDa and the acce... | |||
TMPK-00058 |
CD94 Protein, Human, Recombinant (His & Avi)
KLRD1,KP43,NK cell receptor,CD94 |
Human | HEK293 Cells |
CD94 is an approximately 25 kDa type 2 transmembrane protein that plays an important role in regulating natural killer (NK) cell activation.CD94 plays a role as a receptor for the recognition of MHC class I HLA-E molecules by NK cells and some cytotoxic T-cells. CD94 Protein, Human, Recombinant (His & Avi) is expressed in HEK293 mammalian cells with N-His-Avi tag. The predicted molecular weight is 19.8 kDa and the accession number is Q13241-1. | |||
TMPK-00987 |
IL-2 R gamma/CD132 Protein (Primary Amine Labeling), Cynomolgus, Recombinant (His), Biotinylated
IL-2 R γ/CD132,IL-2 R gamma,IMD4,... |
Cynomolgus | HEK293 Cells |
The gamma chain of the high affinity functional human IL-2 receptor complex belongs to the hematopoietin receptor family. IL-2 R gamma is a 369 amino acid residue protein consisting of a 22 residue signal sequence, a 232 residue extracellular domain, a 29 residue transmembrane domain and an 86 residue cytoplasmic domain. Although IL-2 R gamma by itself does not bind IL-2 with any appreciable affinity, it is required for IL-2 receptor signaling. IL-2 R gamma/CD132 Protein (Primary Amine Labeling)... | |||
TMPK-00748 |
DLL3 Protein, Mouse, Recombinant (His)
Delta3,Pudgy,SCDO1δ3,DLL3,δ3,SCDO1delta3,SCDO1 |
Mouse | HEK293 Cells |
Delta-like protein 3 (DLL3) is a transmembrane protein that belongs to the Delta/Serrate/Lag-2 (DSL) family of Notch ligands. DLL3 inhibits primary neurogenesis. May be required to divert neurons along a specific differentiation pathway. Plays a role in the formation of somite boundaries during segmentation of the paraxial mesoderm (By similarity). DLL3 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with C-His tag. The predicted molecular weight is 49.02 kDa and the acc... | |||
TMPJ-01313 |
HIV-1 gp120 Protein (His)
Envelope glycoprotein gp120,Surface pr... |
HIV | HEK293 Cells |
Envelope glycoprotein gp160 is single-pass type I membrane protein. The mature envelope protein (Env) consists of a homotrimer of non-covalently associated gp120-gp41 heterodimers. It is cleaved into the following 2 chains: glycoprotein 120 and transmembrane protein gp41. The resulting complex protrudes from the virus surface as a spike. The 17 amino acids long immunosuppressive region is present in many retroviral envelope proteins. Synthetic peptides derived from this relatively conserved sequ... | |||
TMPK-00542 |
DLL3 Protein, Cynomolgus, Recombinant (aa 27-488, His)
SCDO1,Delta3,SCDO1δ3,δ3,SCDO1delta3,DLL3,Pudgy |
Cynomolgus | HEK293 Cells |
Delta-like protein 3 (DLL3) is a transmembrane protein that belongs to the Delta/Serrate/Lag-2 (DSL) family of Notch ligands. DLL3 inhibits primary neurogenesis. May be required to divert neurons along a specific differentiation pathway. Plays a role in the formation of somite boundaries during segmentation of the paraxial mesoderm (By similarity). DLL3 Protein, Cynomolgus, Recombinant (aa 27-488, His) is expressed in HEK293 mammalian cells with C-His tag. The predicted molecular weight is 49.21... | |||
TMPK-01210 |
DLL3 Protein (Primary Amine Labeling), Human, Recombinant (His), Biotinylated
DLL3,SCDO1δ3,SCDO1,Pudgy,δ3,SCDO1delta3,Delta3 |
Human | HEK293 Cells |
Delta-like protein 3 (DLL3) is a transmembrane protein that belongs to the Delta/Serrate/Lag-2 (DSL) family of Notch ligands. DLL3 inhibits primary neurogenesis. May be required to divert neurons along a specific differentiation pathway. Plays a role in the formation of somite boundaries during segmentation of the paraxial mesoderm (By similarity). DLL3 Protein (Primary Amine Labeling), Human, Recombinant (His), Biotinylated is expressed in HEK293 mammalian cells with N-His tag. The predicted mo... | |||
TMPK-01395 |
TENM2 Protein, Human, Recombinant (His)
Ten-m2,KIAA1127,Teneurin-2,TNM |
Human | HEK293 Cells |
Teneurin-2 is a member of a novel family of transmembrane proteins characterized to date in fish, birds, mammals, and Drosophila (e.g., the pair-rule gene product Ten-m). Teneurin-2, a vertebrate homologue of the Drosophila pair-rule gene ten-m/odz, is revealed to be a membrane-bound transcription regulator. In the nucleus, the intracellular domain of teneurin-2 colocalizes with promyelocytic leukemia (PML) protein in nuclear bodies implicated in transcription control. | |||
TMPK-00239 |
IL-2 R gamma/CD132 Protein, Human, Recombinant (His & Avi), Biotinylated
SCIDX,IMD4,IL-2 R gamma,CD132,SCIDX1,IL- |
Human | HEK293 Cells |
The gamma chain of the high affinity functional human IL-2 receptor complex belongs to the hematopoietin receptor family. IL-2 R gamma is a 369 amino acid residue protein consisting of a 22 residue signal sequence, a 232 residue extracellular domain, a 29 residue transmembrane domain and an 86 residue cytoplasmic domain. Although IL-2 R gamma by itself does not bind IL-2 with any appreciable affinity, it is required for IL-2 receptor signaling. IL-2 R gamma/CD132 Protein, Human, Recombinant (His... | |||
TMPK-00250 |
SIRP gamma Protein, Human, Recombinant (His & Avi)
SIRP-B2,bA77C3.1,CD172g,SIRP β 2,... |
Human | HEK293 Cells |
Signal regulatory protein gamma (SIRP gamma, designated CD172g), also called SIRP beta 2, is a monomeric 45-47 kDa type I transmembrane protein belonging to the SIRP/SHPS (CD172) family of the Ig superfamily.SIRP gamma is probable immunoglobulin-like cell surface receptor. On binding with CD47, mediates cell-cell adhesion. Engagement on T-cells by CD47 on antigen-presenting cells results in enhanced antigen-specific T-cell proliferation and costimulates T-cell activation. SIRP gamma Protein, Hum... | |||
TMPK-00238 |
IL-2 R gamma/CD132 Protein, Human, Recombinant (His & Avi)
CD132,gammaC,γC,IMD4,IL2RG,SCIDX1,CIDX,IL-... |
Human | HEK293 Cells |
The gamma chain of the high affinity functional human IL-2 receptor complex belongs to the hematopoietin receptor family. IL-2 R gamma is a 369 amino acid residue protein consisting of a 22 residue signal sequence, a 232 residue extracellular domain, a 29 residue transmembrane domain and an 86 residue cytoplasmic domain. Although IL-2 R gamma by itself does not bind IL-2 with any appreciable affinity, it is required for IL-2 receptor signaling. IL-2 R gamma/CD132 Protein, Human, Recombinant (His... | |||
TMPK-01206 |
DLL3 Protein, Human, Recombinant (His & Avi)
DLL3,Pudgy,Delta3,δ3,SCDO1delta3,SCDO1δ3,SCDO1 |
Human | HEK293 Cells |
Delta-like protein 3 (DLL3) is a transmembrane protein that belongs to the Delta/Serrate/Lag-2 (DSL) family of Notch ligands. DLL3 inhibits primary neurogenesis. May be required to divert neurons along a specific differentiation pathway. Plays a role in the formation of somite boundaries during segmentation of the paraxial mesoderm (By similarity). DLL3 Protein, Human, Recombinant (His & Avi) is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 21.20 kDa a... | |||
TMPK-00543 |
DLL3 Protein, Cynomolgus, Recombinant (aa 27-477, His)
DLL3,SCDO1δ3,SCDO1,Pudgy,Delta3,δ3,SCDO1delta3 |
Cynomolgus | HEK293 Cells |
Delta-like protein 3 (DLL3) is a transmembrane protein that belongs to the Delta/Serrate/Lag-2 (DSL) family of Notch ligands. DLL3 inhibits primary neurogenesis. May be required to divert neurons along a specific differentiation pathway. Plays a role in the formation of somite boundaries during segmentation of the paraxial mesoderm (By similarity). DLL3 Protein, Cynomolgus, Recombinant (aa 27-477, His) is expressed in HEK293 mammalian cells with C-His tag. The predicted molecular weight is 48.80... | |||
TMPK-00607 |
LILRB4/CD85k/ILT3 SR & Domain 2 Protein, Human, Recombinant (His & Avi), Biotinylated
ILT-3,ILT3,LILRB4,HM18,LIR5,CD85K |
Human | HEK293 Cells |
LILRB4,also known as CD85k and LIR-5, ILT3, is an approximately 60 kDa transmembrane glycoprotein that negatively regulates immune cell activation. Mature human ILT3 consists of a 238 amino acid (aa) extracellular domain with two Ig-like domains, a 21 aa transmembrane segment, and a 168 aa cytoplasmic domain with 3 immunoreceptor tyrosine-based inhibitory motifs (ITIM).LILRB4 is receptor for class I MHC antigens. Recognizes a broad spectrum of HLA-A, HLA-B, HLA-C and HLA-G alleles. LILRB4/CD85k... | |||
TMPJ-00263 |
VSIG8 Protein, Human, Recombinant (His)
C1orf204,V-set and immunoglobulin domain-containing... |
Human | HEK293 Cells |
V-set and immunoglobulin domain-containing protein 8(VSIG8) is a single-pass type I membrane protein.The human VSIG8 cDNA encodes 414 amino acids (aa) including a 21 aa signal sequence, a 242 aa extracellular domain (ECD) containing 2 Ig-like V-type (immunoglobulin-like) domains, a 21 aa transmembrane domain and a 130 aa cytoplasmic domain.The funtion of VSIG8 is not clear. | |||
TMPJ-01180 |
VSIG8 Protein, Mouse, Recombinant (His)
Vsig8,V-set and immunoglobulin domain-containing protein... |
Mouse | HEK293 Cells |
V-set and immunoglobulin domain-containing protein 8(VSIG8) is a single-pass type I membrane protein.The mouse VSIG8 cDNA encodes 417 amino acids (aa) including a 21 aa signal sequence, a 241 aa extracellular domain (ECD) containing 2 Ig-like V-type (immunoglobulin-like) domains, a 21 aa transmembrane domain and a 134 aa cytoplasmic domain. The function of VSIG8 is not clear. | |||
TMPK-01314 |
LILRB2/CD85d/ILT4 Protein, Cynomolgus, Recombinant (His)
CD85d,ILT4CD85d,LIR2,MIR10,LILRB2,ILT4,ILT... |
Cynomolgus | HEK293 Cells |
The immunoglobulin-like transcript (ILT) comprise a family of activating and inhibitory type immunoreceptors whose genes are located in the same locus that encodes killer cell Ig-like receptors (KIR). ILT4, also known as LIR-2 and LILRB2, is a type I transmembrane protein expressed primarily on monocytes and dendritic cells (DC). LILRB2 is a receptor for class I MHC antigens. Recognizes a broad spectrum of HLA-A, HLA-B, HLA-C, HLA-G and HLA-F alleles. LILRB2/CD85d/ILT4 Protein, Cynomolgus, Recom... | |||
TMPK-00221 |
MICA alpha 3 Protein, Human, Recombinant (mFc)
MICA alpha 3,MICA α 3,MICA,MIC-A |
Human | HEK293 Cells |
MICA (MHC class I chain-related gene A) is a transmembrane glycoprotein that functions as a ligand for human NKG2D. A closely related protein, MICB, shares 85% amino acid identity with MICA. These proteins are distantly related to the MHC class I proteins. They possess three extracellular Ig‑like domains, but they have no capacity to bind peptide or interact with beta 2-microglobulin.. MICA alpha 3 Protein, Human, Recombinant (mFc) is expressed in HEK293 mammalian cells with N-mFc tag. The predi... | |||
TMPK-01101 |
LILRB2/CD85d/ILT4 Domain1 & 2 Protein, Human, Recombinant (His)
LILRB2,ILT-4,CD85d,MIR10,LIR2,ILT4,ILT4CD8... |
Human | HEK293 Cells |
The immunoglobulin-like transcript (ILT) comprise a family of activating and inhibitory type immunoreceptors whose genes are located in the same locus that encodes killer cell Ig-like receptors (KIR). ILT4, also known as LIR-2 and LILRB2, is a type I transmembrane protein expressed primarily on monocytes and dendritic cells (DC). LILRB2 is a receptor for class I MHC antigens. Recognizes a broad spectrum of HLA-A, HLA-B, HLA-C, HLA-G and HLA-F alleles. LILRB2/CD85d/ILT4 Domain1 & 2 Protein, Human... | |||
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