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Search Results for " translocator protein "
Targets Recommended: Others

7

抑制剂 & 化合物

6

重组蛋白

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Cat. No. Product Name Target Signaling Pathways
T22782 FGIN-1-27

Others Others
FGIN 1-27 是一种吲哚乙酰胺,是外周苯二氮卓受体的特异性的配体,Ki 为 5.0 nM。FGIN 1-27 可以透过血脑屏障。FGIN 1-27对异烟肼引起的抽搐发作具有抑制作用。
T2371 Emapunil

AC-5216,XBD-173

Others Others
Emapunil (XBD-173) 是一种选择性的、口服有效的TSPO(一种线粒体苯二氮受体) 的配体。在多种动物模型中,它显示出抗焦虑和抗抑郁特性。
T15162 DPA-714

Others Others
DPA-714 是高亲和力的移位蛋白配体 (Ki=7 nM),它结构中有一个氟原子,能够被氟 -18 进行标记,并可通过正电子发射断层成像进行活体成像。它可在各种神经炎症模型及脑肿瘤模型中成功评估炎症的特异性成像。
T38787 ER176

Others Others
ER176 is a novel PET radioligand utilized for the visualization of 18 kDa translocator protein (TSPO), a neuroinflammation biomarker, marking the advancement in imaging technology.
T16393 ONO-2952

Others Others
ONO-2952 is more selective for TSPO than other receptors, transporters, ion channels, and enzymes. ONO-2952 is a potent and selective translocator protein 18 kDa (TSPO) antagonist (Ki: 0.33-9.30 nM for rat and human TSPO). ONO-2952 has the potential for i
T13691 Etifoxine

HOE 36-801

Others Others
Etifoxine preferentially acts on β2 or β3 subunit-containing GABAA receptors. GABAA receptor Etifoxine exhibits anxiolytic activity in rodents and humans with no sedative, myorelaxant or mnesic side effects. Etifoxine acts as a ligand of the translocator protein (TSPO); promotes axonal regeneration. Etifoxine(HOE 36-801) is potentiator of GABAA receptor function in cultured neurons.
T74571 TSPO Ligand-Linker Conjugates 1

Others Others
TSPO Ligand-Linker Conjugates 1,包含TSPO配体和连接子,用于合成靶向线粒体的AUTAC。该AUTAC能与OMM上TSPO结合,通过mitophagy降解受损线粒体和蛋白质,提升线粒体活性。适用于研究线粒体功能紊乱,包括神经退行性疾病、癌症和糖尿病。

化合物

FGIN-1-27
Cat.No: T22782
Synonym:
Target: Others
Emapunil
Cat.No: T2371
Synonym: AC-5216,XBD-173
Target: Others
DPA-714
Cat.No: T15162
Synonym:
Target: Others
ER176
Cat.No: T38787
Synonym:
Target: Others
ONO-2952
Cat.No: T16393
Synonym:
Target: Others
Etifoxine
Cat.No: T13691
Synonym: HOE 36-801
Target: Others
TSPO Ligand-Linker Conjugates 1
Cat.No: T74571
Synonym:
Target: Others
Cat. No. Product Name Species Expression System
TMPH-00317 BipD Protein, Burkholderia pseudomallei, Recombinant (His & Myc)

Translocator protein BipD,bipD

Burkholderia pseudomallei E. coli
Required for invasion of epithelial cells, as well as for survival within host cells, escape from endocytic vesicles and subsequent actin-tail formation. Probably regulates the secretion of effectors BipB and BipC and their final integration into the target cell membrane. BipD Protein, Burkholderia pseudomallei, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 41.4 kDa and the accession number is Q3JL26.
TMPH-03128 TSPO Protein, Pig, Recombinant (His & Myc & SUMO)

TSPO,Peripheral-type benzodiazepine receptor,Translocato...

Sus scrofa (Pig) E. coli
Promotes the transport of cholesterol across mitochondrial membranes and may play a role in lipid metabolism, but its precise physiological role is controversial. It is apparently not required for steroid hormone biosynthesis. Can bind protoporphyrin IX and may play a role in the transport of porphyrins and heme. Was initially identified as peripheral-type benzodiazepine receptor; can also bind isoquinoline carboxamides. TSPO Protein, Pig, Recombinant (His & Myc & SUMO) is expressed in E. coli e...
TMPH-03718 YopB Protein, Yersinia enterocolitica, Recombinant (His)

Type 3 secretion system translocon protein SctE,sct...

Yersinia enterocolitica E. coli
Plays a role in virulence.
TMPH-00957 ARNT Protein, Human, Recombinant (His)

Hypoxia-inducible factor 1-beta,Class E basic helix-loop-hel...

Human P. pastoris (Yeast)
ARNT Protein, Human, Recombinant (His) is expressed in Yeast.
TMPH-00906 SLC25A6 Protein, Human, Recombinant (His & KSI)

ADP,ATP carrier protein 3,SLC25A6,ADP,ATP carrier <...

Human E. coli
SLC25A6 Protein, Human, Recombinant (His & KSI) is expressed in E. coli expression system with N-6xHis-KSI tag. The predicted molecular weight is 20.2 kDa and the accession number is P12236.
TMPY-01709 HIF-1 alpha Protein, Human, Recombinant (His)

bHLHe78,HIF-1 α,hypoxia inducible factor 1, alpha subunit (b...

Human E. coli
HIF-1 alpha, also known as HIF1A, contains 1 basic helix-loop-helix (bHLH) domain, 1 PAC (PAS-associated C-terminal) domain, and 2 PAS (PER-ARNT-SIM) domains. It is one of the two subunits of Hypoxia-inducible factor-1 (HIF1). HIF1 is a transcription factor found in mammalian cells cultured under reduced oxygen tension that plays an essential role in cellular and systemic homeostatic responses to hypoxia. HIF1 is a heterodimer composed of an alpha subunit and a beta subunit. The beta subunit has...

重组蛋白

BipD Protein, Burkholderia pseudomallei, Recombinant (His & Myc)
Cat.No: TMPH-00317
Species: Burkholderia pseudomallei
Expression System: E. coli
TSPO Protein, Pig, Recombinant (His & Myc & SUMO)
Cat.No: TMPH-03128
Species: Sus scrofa (Pig)
Expression System: E. coli
YopB Protein, Yersinia enterocolitica, Recombinant (His)
Cat.No: TMPH-03718
Species: Yersinia enterocolitica
Expression System: E. coli
ARNT Protein, Human, Recombinant (His)
Cat.No: TMPH-00957
Species: Human
Expression System: P. pastoris (Yeast)
SLC25A6 Protein, Human, Recombinant (His & KSI)
Cat.No: TMPH-00906
Species: Human
Expression System: E. coli
HIF-1 alpha Protein, Human, Recombinant (His)
Cat.No: TMPY-01709
Species: Human
Expression System: E. coli
TargetMol Loading
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