Cat. No. | Product Name | Species | Expression System |
---|---|---|---|
TMPH-02385 |
Lake Victoria marburgvirus (MARV) (strain Musoke-80) VP30 Protein (His & Myc)
Minor nucleoprotein VP30,Transcription... |
MARV | E. coli |
Acts as a transcription anti-termination factor immediately after transcription initiation, but does not affect transcription elongation. This function has been found to be dependent on the formation of an RNA secondary structure at the transcription start site of the first gene. | |||
TMPH-03729 |
Zaire ebolavirus (strain Kikwit-95) VP30 Protein (His)
Transcriptional activator VP3... |
ZEBOV | E. coli |
Multifunctional protein that acts as a viral transcriptional activator. Promotes read-through of an RNA hairpin in the NP open reading frame to enhance viral transcription. Mechanistically, nonphosphorylated VP30 hexamers form a ternary complex with the viral leader RNA. Clamps the RNA template and the complex VP35-polymerase L together, thereby increasing the polymerase affinity for the RNA template to increase transcription initiation despite the presence of RNA secondary structures. Assists a... |