Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T35536 |
Tpl2 Kinase Inhibitor (hydrochloride)
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Others | Others |
Tpl2 kinase inhibitor is an inhibitor of tumor progression locus 2 (Tpl2; IC50= 0.05 μM).1It is selective for Tpl2 over MEK, p38 MAPK, Src, MK2, and PKC (IC50s = >40, 180, >400, 110, and >400 μM, respectively). Tpl2 kinase inhibitor inhibits LPS-induced TNF-α production in isolated human monocytes and whole blood (IC50s = 0.7 and 8.5 μM, respectively). It enhances differentiation induced by calcitriol in HL-60 and U937 leukemia cells when used at a concentration of 5 μM.2Tpl2 kinase inhibitor (5... | |||
T26284 |
Tpl2-IN-I
Tpl2 inhibitor I,Tpl2-inhibitor-I,Tpl2 IN I,Tpl2 kinase inhibitor |
Others | Others |
Tpl2-IN-I is an inhibitor of tumour progression locus 2 (Tpl2) kinase. |