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Search Results for " thiamine "

Targets Recommended: HIV Protease Endogenous Metabolite

15

抑制剂 & 化合物

7

天然产物

6

重组蛋白

1

同位素标记化合物

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Cat. No.	Product Name	Target	Signaling Pathways
T20062	Thiamine disulfide 二硫化硫胺,TDS,Daiomin,Algoneurina	HIV Protease; Endogenous Metabolite	Metabolism; Microbiology/Virology; Proteases/Proteasome
	Thiamine disulfide (Algoneurina) 是一种存在于食物中的维生素，可作为膳食补充剂和药物生产。它还充当许多中枢代谢酶的辅助因子。
T19579	Thiamine diphosphate analog 1	Others	Others
	Thiamine diphosphate analog 1, an analog of Thiamine diphosphate (the active form of vitamin B1 and a universal cofactor in key cellular pathways), mirrors the structure and potentially the function of its prototype.
T67227	Thiamine Thiocarbamate	Others	Others
	3-((((4-Amino-2-methylpyrimidin-5-yl)methyl)carbamothioyl)thio)-4-oxopentyl acetate 是一种有用的有机化合物，可用于生命科学领域的相关研究，其产品编号为 T67227。
T12158	N3PT N3-pyridyl thiamine	Others	Others
	N3PT is a potent and selective inhibitor of transketolase(TK) with IC50 of 22 nM for Apo-TK)
T36947	Pyrithiamine (hydrobromide)	Others	Others
	Pyrithiamine is the pyridine analog of thiamine that prevents growth of organisms that require intact thiamine. [1] It inhibits the growth of bacterial and fungal species at a pyrithiamine:thiamine ratio of 10:1 in growth media and induces symptoms of thiamine deficiency in mice at a dietary ratio of 3:1. These effects are reversible with addition of sufficient thiamine in all species. Pyrithiamine inhibits the formation of cocarboxylase from thiamine in chicken blood in a dose-dependent manner....
T71783	Oxythiamine chloride HCl	Others	Others
	Oxythiamine chloride HCl is a thiamine antimetabolite that has anticancer activities. It is converted by thiamine pyrophosphokinase to oxythiamine pyrophosphate, a transketolase inhibitor. Oxythiamine decreases transketolase activity in breast cancer. It inhibits the nonoxidative synthesis of ribose and decreases RNA and DNA synthesis in pancreatic cancer. In vivo, oxythiamine induces cell cycle arrest at the G1 phase and apoptosis in an adenocarcinoma model. Oxythiamine, in combination with sor...
T12354L	Oxythiamine diphosphate	Others	Others
	Oxythiamine diphosphate is a competitivethiamine pyrophosphate inhibitor(Ki of 30 nM).
T12354	Oxythiamine Hydroxythiamin	Others	Others
	Oxythiamine is an antimetabolite and an antagonist of vitamin B1.
T64282	Oxythiamine diphosphate ammonium	Others	Others
	Oxythiamin diphosphate ammonium 是一种转酮酶 (TK) 的有效抑制剂。
T1129	Benfotiamine Benzoylthiamine monophosphate,S-Benzoylthiamine O-monophosphate,苯磷硫胺	Others	Others
	Benfotiamine (S-Benzoylthiamine O-monophosphate) 是维生素 B1 的类似物，其吸收率和生物利用度比维生素B1高，具有直接抗氧化能力，可防止DNA 损伤。它常用作糖尿病并发症的食品补充剂。
T0872L	Amprolium Hydrochloride Amprovine,氨丙啉盐酸盐,Amprolio,Amprolium HCl,安普罗林盐酸盐	Parasite	Microbiology/Virology
	Amprolium Hydrochloride (Amprolium HCl) 是用于家禽的一种干扰硫胺素代谢的抗球虫药，通过抑制硫胺素吸收和碳水化合物合成而抑制球虫的硫胺转运。
T4552	Fursultiamine Diteftin,呋喃硫胺,Judolor,Alinamin F	Others	Others
	Fursultiamine (Alinamin F) 是维生素 B1衍生物，具有抗伤害和抗肿瘤作用。它可用于研究维生素 B1缺乏病、骨关节炎和癌症。
T0872	Amprolium 氨丙啉,安普罗林	Others; Parasite	Microbiology/Virology; Others
	Amprolium 是一种干扰硫胺素代谢的兽用球虫抑制剂。
T81788	Mito-SilylDCA	Others	Others
	Mito-SilylDCA 是一种针对线粒体网络中的 PDK1 的丙酮酸氢酶激酶抑制剂。这种化合物结合了具有靶向 TPP 部分的 DCA 分子，以及聚乙烯长链与硅基，以实现其对 PDK1 的抑制作用。
T76143	Pyruvate oxidase	Others	Others
	Pyruvate oxidase(PoxB) 是一种焦磷酸硫胺素依赖型的氧化酶，可以催化丙酮酸氧化脱羧生成乙酰磷酸、二氧化碳和水。Pyruvate oxidase 是细菌代谢中的一种重要酶，常用于生化研究。

化合物

Thiamine disulfide

Cat.No: T20062

Synonym: 二硫化硫胺,TDS,Daiomin,Algoneurina

Target: HIV Protease, Endogenous Metabolite

Thiamine diphosphate analog 1

Cat.No: T19579

Target: Others

Thiamine Thiocarbamate

Cat.No: T67227

Target: Others

Cat.No: T12158

Synonym: N3-pyridyl thiamine

Target: Others

Pyrithiamine (hydrobromide)

Cat.No: T36947

Target: Others

Oxythiamine chloride HCl

Cat.No: T71783

Target: Others

Oxythiamine diphosphate

Cat.No: T12354L

Target: Others

Cat.No: T12354

Synonym: Hydroxythiamin

Target: Others

Oxythiamine diphosphate ammonium

Cat.No: T64282

Target: Others

Cat.No: T1129

Synonym: Benzoylthiamine monophosphate,S-Benzoylthiamine O-monophosphate,苯磷硫胺

Target: Others

Amprolium Hydrochloride

Cat.No: T0872L

Synonym: Amprovine,氨丙啉盐酸盐,Amprolio,Amprolium HCl,安普罗林盐酸盐

Target: Parasite

Cat.No: T4552

Synonym: Diteftin,呋喃硫胺,Judolor,Alinamin F

Target: Others

Cat.No: T0872

Synonym: 氨丙啉,安普罗林

Target: Others, Parasite

Cat.No: T81788

Target: Others

Pyruvate oxidase

Cat.No: T76143

Target: Others

Cat. No.	Product Name	Target	Signaling Pathways
T2O2741	Thiamine monochloride Thiamine chloride,Vitamin B1	Others; Antioxidant; Endogenous Metabolite; Antibacterial	Metabolism; Microbiology/Virology; Others; oxidation-reduction
	Thiamine monochloride (Vitamin B1) 是人体必不可少的维生素，具有促红细胞生成、调节血糖、抗氧化和调节情绪的作用。Thiamine monochloride 抑制铅引起的脂质过氧化反应，从而防止铅中毒。Thiamine monochloride 在摄入食物的细胞产生能量中起重要作用，并能增强正常的神经元活性。
T0894	Thiamine hydrochloride 盐酸硫胺素,Vitamin B1,Vitamin B1 hydrochloride,Thiamine HCl,盐酸硫胺（维生素B1）,Thiamine chloride hydrochloride	Apoptosis; HBV; Endogenous Metabolite	Apoptosis; Metabolism; Microbiology/Virology
	Thiamine hydrochloride (Vitamin B1) 是一种必需的微量营养素，是许多中枢代谢酶的辅因子。
T4874	Thiamine pyrophosphate Cocarboxylase,焦磷酸硫胺素,Aneurinepyrophosphoric acid,Thiamine pyrophosphate chloride	Endogenous Metabolite	Metabolism
	Thiamine pyrophosphate (Cocarboxylase) 是维生素 B1 的辅酶形式，是丙酮酸脱氢酶复合物和酮戊二酸脱氢酶复合物的必需中间体，能够用于研究评估生物系统中的脱羧机制。
T4925	Thiamine monophosphate chloride (dihydrate) Thiamine monophosphate chloride dihydrat,胺氯化亚磷酸酯,Aneurine monophosphate chloride	Others; Endogenous Metabolite	Metabolism; Others
	Thiamine monophosphate chloride dihydrate (Aneurine monophosphate chloride) 是内源性代谢产物的一种。
T8021	Dibenzoyl Thiamine Bentiamine,二苯甲酰硫胺素	Others	Others
	Dibenzoyl Thiamine (Bentiamine) 是一种硫胺素的衍生物。它在体内被迅速吸收，并转化成硫胺素。
T13923	Thiamine nitrate 硝酸硫胺,Vitamin B1 nitrate	Others	Others
	Thiamine nitrate (Vitamin B1 nitrate) 是必不能够少的维生素，能够提高正常的神经元活性。
T4804	Pyruvic acid BTS,Pyroracemic acid,α-Ketopropionic acid,2-Oxopropionic acid,Acetylformic acid,丙酮酸,NSC 179	Others; Endogenous Metabolite	Metabolism; Others
	Pyruvic acid (Acetylformic acid) 是碳水化合物，是蛋白质和脂肪代谢的中间产物。

天然产物

Thiamine monochloride

Cat.No: T2O2741

Synonym: Thiamine chloride,Vitamin B1

Target: Others, Antioxidant, Endogenous Metabolite, Antibacterial

Thiamine hydrochloride

Cat.No: T0894

Synonym: 盐酸硫胺素,Vitamin B1,Vitamin B1 hydrochloride,Thiamine HCl,盐酸硫胺（维生素B1）,Thiamine chloride hydrochloride

Target: Apoptosis, HBV, Endogenous Metabolite

Thiamine pyrophosphate

Cat.No: T4874

Synonym: Cocarboxylase,焦磷酸硫胺素,Aneurinepyrophosphoric acid,Thiamine pyrophosphate chloride

Target: Endogenous Metabolite

Thiamine monophosphate chloride (dihydrate)

Cat.No: T4925

Synonym: Thiamine monophosphate chloride dihydrat,胺氯化亚磷酸酯,Aneurine monophosphate chloride

Target: Others, Endogenous Metabolite

Dibenzoyl Thiamine

Cat.No: T8021

Synonym: Bentiamine,二苯甲酰硫胺素

Target: Others

Thiamine nitrate

Cat.No: T13923

Synonym: 硝酸硫胺,Vitamin B1 nitrate

Target: Others

Cat.No: T4804

Synonym: BTS,Pyroracemic acid,α-Ketopropionic acid,2-Oxopropionic acid,Acetylformic acid,丙酮酸,NSC 179

Target: Others, Endogenous Metabolite

Species：

Expression System：

Tag：

Cat. No.	Product Name	Species	Expression System
TMPH-02333	SLC25A19 Protein, Human, Recombinant (His) Mitochondrial thiamine pyrophosphate transporter,SL...	Human	E. coli
	Mitochondrial transporter mediating uptake of thiamine pyrophosphate (ThPP) into mitochondria. SLC25A19 Protein, Human, Recombinant (His) is expressed in E. coli expression system with N-10xHis tag. The predicted molecular weight is 37.0 kDa and the accession number is Q9HC21.
TMPJ-00514	ACPP Protein, Human, Recombinant (His) Ecto-5'-Nucleotidase,TMPase,5'-Nucleotidase,Thiamine	Human	HEK293 Cells
	Prostatic Acid Phosphatase (PAP) belongs to the histidine acid phosphatase family. PAP can catalyze the hydrolysis of member of phosphate monoestyers, including phosphorylated protein. PAP can high expression in metastasized prostate cancer, moderately expression level in bone diseases, blood cell disease, and the concentration of PAP is used to monitor and assess the proession of prostate cancer. The optimum PH of PAP is from 4 to 6; its activity can be inhibited by L(+)-tartrate.
TMPH-00850	OGDC-E1 Protein, Human, Recombinant (His & SUMO) OGDH,Alpha-ketoglutarate dehydrogenase,2-oxoglutarate dehydr...	Human	E. coli
	OGDC-E1 Protein, Human, Recombinant (His & SUMO) is expressed in E. coli expression system with N-6xHis-SUMO tag. The predicted molecular weight is 59.1 kDa and the accession number is Q02218.
TMPH-02475	OGDC-E Protein, Mouse, Recombinant (His & SUMO) Ogdh,Alpha-ketoglutarate dehydrogenase,Thiamine dip...	Mouse	E. coli
	OGDC-E Protein, Mouse, Recombinant (His & SUMO) is expressed in E. coli expression system with N-6xHis-SUMO tag. The predicted molecular weight is 50.8 kDa and the accession number is Q60597.
TMPY-04773	TPK1 Protein, Human, Recombinant (His) THMD5,PP20,HTPK1,thiamin pyrophosphokinase 1	Human	E. coli
	Thiamine pyrophosphokinase (TPK) produces thiamine pyrophosphate, a cofactor for a number of enzymes, including pyruvate dehydrogenase and 2-ketoglutarate dehydrogenase. Episodic encephalopathy type thiamine metabolism dysfunction (OMIM 614458) due to TPK1 mutations is a recently described rare disorder. The genomic variations in the fetal and maternal TPK1 gene could contribute to the variability of birth weight in normal humans.
TMPH-00870	ILVBL Protein, Human, Recombinant (His) IlvB-like protein,Acetolactate synthase-like protein,ILVBL,2...	Human	E. coli
	Endoplasmic reticulum 2-OH acyl-CoA lyase involved in the cleavage (C1 removal) reaction in the fatty acid alpha-oxydation in a thiamine pyrophosphate (TPP)-dependent manner. Involved in the phytosphingosine degradation pathway. ILVBL Protein, Human, Recombinant (His) is expressed in E. coli expression system with N-10xHis tag. The predicted molecular weight is 70.7?kDa and the accession number is A1L0T0.

重组蛋白

SLC25A19 Protein, Human, Recombinant (His)

Cat.No: TMPH-02333

Species: Human

Expression System: E. coli

ACPP Protein, Human, Recombinant (His)

Cat.No: TMPJ-00514

Species: Human

Expression System: HEK293 Cells

OGDC-E1 Protein, Human, Recombinant (His & SUMO)

Cat.No: TMPH-00850

Species: Human

Expression System: E. coli

OGDC-E Protein, Mouse, Recombinant (His & SUMO)

Cat.No: TMPH-02475

Species: Mouse

Expression System: E. coli

TPK1 Protein, Human, Recombinant (His)

Cat.No: TMPY-04773

Species: Human

Expression System: E. coli

ILVBL Protein, Human, Recombinant (His)

Cat.No: TMPH-00870

Species: Human

Expression System: E. coli

Cat. No.	Product Name	Target	Signaling Pathways
TMIJ-0377	Thiamine Hydrochloride-13C4
	Thiamine Hydrochloride-13C4 是 Thiamine Hydrochloride 的 13C 的标记化合物。Thiamine Hydrochloride 的 CAS 号为 67-03-8。Thiamine hydrochloride 是一种必需的微量营养素，是许多中枢代谢酶的辅因子。

同位素标记化合物

Thiamine Hydrochloride-13C4

Cat.No: TMIJ-0377

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