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TMPH-03651
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Tyr p 2 Protein, Tyrophagus putrescentiae, Recombinant (His)
Mite group 2 allergen Tyr p 2
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Tyrophagus putrescentiae
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E. coli
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N/A. Tyr p 2 Protein, Tyrophagus putrescentiae, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 17.3 kDa and the accession number is O02380. |
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TMPH-02269
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Tyrosinase/TYR Protein, Human, Recombinant (His)
Tyrosinase,SK29-AB,Monophenol monooxygenase,Tumor r...
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Human
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P. pastoris (Yeast)
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This is a copper-containing oxidase that functions in the formation of pigments such as melanins and other polyphenolic compounds. Catalyzes the initial and rate limiting step in the cascade of reactions leading to melanin production from tyrosine. In addition to hydroxylating tyrosine to DOPA (3,4-dihydroxyphenylalanine), also catalyzes the oxidation of DOPA to DOPA-quinone, and possibly the oxidation of DHI (5,6-dihydroxyindole) to indole-5,6 quinone. |
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TMPH-02270
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Tyrosinase/TYR Protein, Human, Recombinant (His & SUMO)
SK29-AB,LB24-AB,TYR,Monophenol monooxygenase,Ty...
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Human
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E. coli
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This is a copper-containing oxidase that functions in the formation of pigments such as melanins and other polyphenolic compounds. Catalyzes the initial and rate limiting step in the cascade of reactions leading to melanin production from tyrosine. In addition to hydroxylating tyrosine to DOPA (3,4-dihydroxyphenylalanine), also catalyzes the oxidation of DOPA to DOPA-quinone, and possibly the oxidation of DHI (5,6-dihydroxyindole) to indole-5,6 quinone. |
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TMPH-02304
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Vasohibin-2/VASH2 Protein, Human, Recombinant (His & SUMO)
Vasohibin-2,VASH2,Vasohibin-like protein,Tubulinyl-Tyr
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Human
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E. coli
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Tyrosine carboxypeptidase that removes the C-terminal tyrosine residue of alpha-tubulin, thereby regulating microtubule dynamics and function. Critical for spindle function and accurate chromosome segregation during mitosis since microtuble detyronisation regulates mitotic spindle length and postioning. Acts as an activator of angiogenesis: expressed in infiltrating mononuclear cells in the sprouting front to promote angiogenesis. Plays a role in axon formation. Vasohibin-2/VASH2 Protein, Human,... |
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TMPH-02263
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VASH1 Protein, Human, Recombinant (His)
Tubulin carboxypeptidase 1,Tubulinyl-Tyr carboxypep...
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Human
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E. coli
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VASH1 Protein, Human, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 27.3 kDa and the accession number is Q7L8A9. |
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TMPJ-01241
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DTD1 Protein, Human, Recombinant (His)
DUE-B,D-tyrosyl-tRNA(Tyr) deacylase 1,DNA-...
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Human
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HEK293 Cells
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D-tyrosyl-tRNA(Tyr) deacylase 1(DTD1) belongs to the DTD family, and expressed in many adult and fetal tissues such as testis, ovary, spleen in adult and fetal brain. It is a nucleus and cytoplasm located protein, and is preferentially phosphorylated in cells arrested early in S phase. DTD1 is an ATPase involved in DNA replication, it may facilitate loading of CDC45 onto pre-replication complexes. The protein may hydrolyze D-tyrosyl-tRNA(Tyr) into D-tyrosine and free tRNA(Tyr), a possible defens... |
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TMPY-01693
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Butyrylcholinesterase Protein, Human, Recombinant (His)
CHE1,E1,butyrylcholinesterase,CHE2
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Human
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HEK293 Cells
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Butyrylcholinesterase Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 66.5 kDa and the accession number is P06276. |
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TMPY-01596
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Butyrylcholinesterase Protein, Mouse, Recombinant (His)
C730038G20Rik,butyrylcholinesterase
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Mouse
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HEK293 Cells
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Butyrylcholinesterase Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 66.7 kDa and the accession number is Q03311. |
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TMPK-00901
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TYRO3 Protein, Mouse, Recombinant (His)
BYK,TYRO3,Brt,Rse,TIF,DTK,SKY
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Mouse
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HEK293 Cells
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TYRO3 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with C-His tag. The predicted molecular weight is 43 kDa and the accession number is P55144-2. |
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TMPH-00415
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BoNT/E Protein, Clostridium butyricum, Recombinant (His & SUMO)
Bontoxilysin-E,BoNT/E,Botulinum neurotoxin type E
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Clostridium butyricum
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E. coli
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BoNT/E Protein, Clostridium butyricum, Recombinant (His & SUMO) is expressed in E. coli expression system with N-6xHis-SUMO tag. The predicted molecular weight is 63.7 kDa and the accession number is P30995. |
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TMPK-00533
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TYRO3 Protein, Cynomolgus, Recombinant (His)
TIF,DTK,Rse,Brt,TYRO3,SKY,BYK
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Cynomolgus
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HEK293 Cells
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TYRO3 Protein, Cynomolgus, Recombinant (His) is expressed in HEK293 mammalian cells with C-His tag. The predicted molecular weight is 42.47 kDa and the accession number is A0A2K5WCY8. |
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TMPY-02587
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Tyrosine Hydroxylase Protein, Mouse, Recombinant (His)
tyrosine hydroxylase
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Mouse
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Baculovirus Insect Cells
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Tyrosine Hydroxylase Protein, Mouse, Recombinant (His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 58 kDa and the accession number is P24529. |
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TMPY-02401
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Tyrosine Hydroxylase Protein, Human, Recombinant (His)
tyrosine hydroxylase,DYT14,TYH,DYT5b
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Human
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Baculovirus Insect Cells
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Tyrosine Hydroxylase Protein, Human, Recombinant (His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 57.6 kDa and the accession number is P07101-3. |
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TMPY-04544
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MEK2 Protein, Human, Recombinant (GST)
mitogen-activated protein kinase kinase 2,FLJ26075,MKK2,CFC4...
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Human
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Baculovirus Insect Cells
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Dual specificity mitogen-activated protein kinase kinase 2, also known as MAP kinase kinase 2, MAPKK2, ERK activator kinase 2, MAPK / ERK kinase 2, MEK2 and MAP2K2, is a member of the protein kinase superfamily, STE Ser/Thr protein kinase family and MAP kinase kinase subfamily. MAP2K2 / MEK2 contains one protein kinase domain. MEK1 and MEK2 (also known as MAP2K1 and MAP2K2, respectively) are evolutionarily conserved, dual-specificity kinases that mediate Erk1 and Erk2 activation during adhesion ... |
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TMPJ-00412
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VEGFR1/FLT-1 Protein, Human, Recombinant (hFc)
Vascular endothelial growth factor receptor 1,Vascular perme...
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Human
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HEK293 Cells
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Human Vascular endothelial growth factor receptor 1(VEGFR-1, FLT-1) is a member of the the class III subfamily of receptor tyrosine kinases (RTKs) and Tyr protein kinase family and CSF-1/PDGF receptor subfamily. VEGFR-1 is widely expressed in human tissues including normal lung, placenta, liver, kidney, heart and brain tissues. It is specifically expressed in most of the vascular endothelial cellsand peripheral blood monocytes. VEGFR-1 contains seven Ig-like C2-type domains and one protein kinas... |
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TMPH-02279
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YARS1 Protein, Human, Recombinant (GST)
Tyrosine--tRNA ligase, cytoplasmic,Tyrosyl...
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Human
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E. coli
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Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr). YARS1 Protein, Human, Recombinant (GST) is expressed in E. coli expression system with N-GST tag. The predicted molecular weight is 86.0 kDa and the accession number is P54577. |
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TMPH-02778
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Mcpt4 Protein, Mouse, Recombinant (E. coli, His)
MSMCP,Mast cell protease 4,Myonase,Serosal mast cell proteas...
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Mouse
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E. coli
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Has chymotrypsin-like activity. Hydrolyzes the amide bonds of synthetic substrates having Tyr and Phe residues at the P1 position. Preferentially hydrolyzes the 'Tyr-4-|-Ile-5' bond of angiotensin I and the 'Phe-20-|-Ala-21' bond of amyloid beta-protein, and is less active towards the 'Phe-8-|-His-9' bond of angiotensin I and the 'Phe-4-|-Ala-5' and 'Tyr-10-|-Glu-11' bonds of amyloid beta-protein. Involved in thrombin regulation and fibronectin processing. Mcpt4 Protein, Mouse, Recombinant (E. c... |
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TMPJ-01050
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GRB2 Protein, Human, Recombinant (His)
Growth Factor Receptor-Bound Protein 2,SH2/SH3 Adapter GRB2,...
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Human
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E. coli
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As an adaptor protein, Growth Factor Receptor-Bound Protein 2 (GRB2) is involved in siganl transduction and consists of a central SH2 domain flanked by two SH3 domains. GRB2 associates with activated Tyr-phosphorylated EGF receptor/EGFR and PDGF receptors via its SH2 domain, stimulating GTP binding to Ras, which in turn activates MAPK and other signaling pathway.It also associates to other cellular Tyr-phosphorylated proteins such as SIT1, IRS1, IRS4, SHC and LNK. probably via the concerted acti... |
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TMPH-02277
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PTPN11 Protein, Human, Recombinant (T253M & Q257L, His)
Protein-tyrosine phosphatase 1D,Tyrosine-p...
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Human
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E. coli
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Acts downstream of various receptor and cytoplasmic protein tyrosine kinases to participate in the signal transduction from the cell surface to the nucleus. Positively regulates MAPK signal transduction pathway. Dephosphorylates GAB1, ARHGAP35 and EGFR. Dephosphorylates ROCK2 at 'Tyr-722' resulting in stimulation of its RhoA binding activity. Dephosphorylates CDC73. Dephosphorylates SOX9 on tyrosine residues, leading to inactivate SOX9 and promote ossification. |
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TMPH-02732
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IFNAR2 Protein, Mouse, Recombinant (His)
Ifnar2,Type I interferon receptor 2,Interferon alpha/beta re...
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Mouse
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P. pastoris (Yeast)
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Associates with IFNAR1 to form the plasma membrane receptor in the type I interferon signaling pathway. Directly involved in signal transduction through its association with the TYR kinase JAK1. Involved in interferon-mediated STAT1, STAT2 and STAT3 activation.; May be potent inhibitors of type I IFN receptor activity.; May be potent inhibitors of type I IFN receptor activity. IFNAR2 Protein, Mouse, Recombinant (His) is expressed in yeast with N-6xHis tag. The predicted molecular weight is 26.8 ... |
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TMPJ-00724
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LDHA Protein, Human, Recombinant (His)
LDH-M,Renal Carcinoma Antigen NY-REN-59,Cell Proliferation-I...
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Human
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E. coli
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L-Lactate Dehydrogenase A Chain (LDHA) is an enzyme that catalyzes the conversion of L-lactate and NAD+ to pyruvate and NADH in the final step of anaerobic glycolysis. LDHA contains an N-terminal coenzyme binding region, a central catalytic site, and at least nine utilized Lys acetylation and two Tyr phosphorylation sites. LDHA belongs to the lactate dehydrogenase family, expressed predominantly in muscle tissue. LDHA mutations have been linked to exertional myoglobinuria. |
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TMPJ-01176
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SEMA4C Protein, Mouse, Recombinant (hFc)
M-Sema F,Semaphorin-C-like 1,Semai,Semaphorin I,Sema4c,Semac...
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Mouse
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HEK293 Cells
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Semaphorin-4C is a protein which belongs to the semaphorin family, contains 1 Ig-like C2-type domain, 1 PSI domain, 1 Sema domain. As cell surface receptor for PLXNB2, it plays an important role in cell-cell signaling. PLXNB2 binding promotes downstream activation of RHOA and phosphorylation of ERBB2 at 'Tyr-1248'. It required for normal brain development, axon guidance and cell migration, Probable signaling receptor which may play a role in myogenic differentiation through activation of the str... |
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TMPH-02180
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TTBK2 Protein, Human, Recombinant (His & Myc)
Tau-tubulin kinase 2,TTBK2
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Human
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E. coli
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Serine/threonine kinase that acts as a key regulator of ciliogenesis: controls the initiation of ciliogenesis by binding to the distal end of the basal body and promoting the removal of CCP110, which caps the mother centriole, leading to the recruitment of IFT proteins, which build the ciliary axoneme. Has some substrate preference for proteins that are already phosphorylated on a Tyr residue at the +2 position relative to the phosphorylation site. Able to phosphorylate tau on serines in vitro. |
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TMPH-01088
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CBX5 Protein, Human, Recombinant (His & Myc)
HP1 alpha,CBX5,Heterochromatin protein 1 homolog alpha,Chrom...
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Human
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E. coli
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Component of heterochromatin that recognizes and binds histone H3 tails methylated at 'Lys-9' (H3K9me), leading to epigenetic repression. In contrast, it is excluded from chromatin when 'Tyr-41' of histone H3 is phosphorylated (H3Y41ph). Can interact with lamin-B receptor (LBR). This interaction can contribute to the association of the heterochromatin with the inner nuclear membrane. Involved in the formation of functional kinetochore through interaction with MIS12 complex proteins. CBX5 Protein... |
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TMPK-00177
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LAIR1 Protein, Human, Recombinant (His & Avi)
CD305,LAIR1,LAIR-1,HLAIR1
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Human
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HEK293 Cells
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LAIR1 (leukocyte-associated Ig-like receptor-1, designated CD305) is an approximately 40 kDa type I transmembrane inhibitory glycoprotein belonging to the Ig superfamily.LAIR1 functions as an inhibitory receptor that plays a constitutive negative regulatory role on cytolytic function of natural killer (NK) cells, B-cells and T-cells. Activation by Tyr phosphorylation results in recruitment and activation of the phosphatases PTPN6 and PTPN11. It also reduces the increase of intracellular calcium ... |
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TMPJ-01184
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CPA4 Protein, Mouse, Recombinant (His)
CPA4,Carboxypeptidase A4
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Mouse
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HEK293 Cells
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Carboxypeptidase A4 (CPA4) is a member of the peptidase M14 family. CPA4 is metalloprotease that could be involved in the histone hyperacetylation pathway. CPA4 binds one zinc ion per subunit and could catalyze to release of a C-terminal amino acid, with preference for -Phe, -Leu, -Ile, -Met, -Tyr and -Val.They have distinct expression patterns and different specificities for example, preferentially cleaving aromatic (carboxypeptidase As) or basic (carboxypeptidase Bs) residues. Several, such as... |
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TMPY-03125
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SHP-2 Protein, Mouse, Recombinant (His)
SAP-2,Syp,PTP1D,SH-PTP2,SH-PTP3,SHP-2,PTP2C,2700084A17Rik,AW...
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Mouse
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HEK293 Cells
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SHP2, also known as PTPN11, belongs to the protein-tyrosine phosphatase(PTP) family, non-receptor class 2 subfamily. PTPs catalyze the removal of phosphate groups from tyrosine residues by the hydrolysis of phosphoric acid monoesters. They dephosphorylate EGFR, JAK2 and TYK2 kinases, promoting oncogenic transformation. SHP2 is widely expressed, with highest levels in heart, brain, and skeletal muscle. SHP2 acts downstream of various receptor and cytoplasmic protein tyrosine kinases to participat... |
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TMPJ-00791
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HER2/ERBB2 Protein, Rat, Recombinant (E. coli, His)
p185erbB2,Epidermal growth factor receptor-related protein,p...
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Rat
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E. coli
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ERBB2 belongs to the protein kinase superfamily, Tyr protein kinase family and EGF receptor subfamily. It contains a protein kinase domain. ERBB2 is widely expressed in epithelial cells, and amplification and/or overexpression of ErbB2 has been reported associated with malignancy and a poor prognosis in numerous carcinomas, including breast, prostate and ovarian cancers. Rat ERBB2 is an essential component of a neuregulin-receptor complex, although neuregulins do not interact with it alone. ErbB... |
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TMPJ-00331
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IFNAR1 Protein, Rhesus macaque, Recombinant (His)
IFN-al,CRF2-1,IFN-alpha/beta receptor 1,human interferon-α r...
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Rhesus
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HEK293 Cells
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Interferon‑alpha/beta receptor 1 (IFN‑ alpha / beta R1), also known as IFNAR1, are present in all tissues and even on the surface of most IFN-resistant cells. Isoform 1, isoform 2 and isoform 3 are expressed in the IFN-alpha sensitive myeloma cell line U266B1. Isoform 2 and isoform 3 are expressed in the IFN-alpha resistant myeloma cell line U266R. Isoform 1 is not expressed in IFN-alpha resistant myeloma cell line U266R. It interacts with STAT1 and STAT2, the interaction requires its phosphory... |
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TMPY-02595
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DUSP14 Protein, Human, Recombinant (His & MBP)
MKP6,MKP-L,dual specificity phosphatase 14
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Human
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E. coli
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Dual specific phosphatase 14 / MAP-kinase phophatase-6 (DUSP14 / MKP6) is a member of Dual-specificity phosphatases that is a subclass of protein tyrosine phosphatases (PTP) families that can dephosphorylate bothe phosphotyrosine and phosphoserine / phosphothreonine residues in substrates. Unlike many other DUSPs, DUSP14 only contains a catalytic domain within the C-terminal region. In signal transduction, DUSP14 has been considered as negative regulator of the mitogen-activated protein kinase (... |
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TMPJ-00552
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LILRB2/CD85d/ILT4 Protein, Human, Recombinant (Avi & His), Biotinylated
Leukocyte Immunoglobulin-Like Receptor 2,Monocyte/Macrophage...
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Human
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HEK293 Cells
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Members of the immunoglobulin-like transcript (ILT) family are activating and inhibitory immunoreceptors whose genes are located same locus that encodes killer cell Ig-like receptors (KIR). Leukocyte Immunoglobulin-Like Receptor Subfamily B Member 2 (LIR-2) is a type I transmembrane protein. LIR-2 is expressed primarily on monocytes and dendritic cells (DC). Human LIR-2 is produced as a 598 amino acino acid precursor including a 21 aa signal sequence, a 440 aa extracellular domain (ECD), a 21 aa... |
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TMPY-04388
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BLK Protein, Human, Recombinant (GST)
MODY11,BLK proto-oncogene, Src family tyrosine kina...
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Human
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Baculovirus Insect Cells
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Tyrosine-protein kinase Blk, also known as B lymphocyte kinase, p55-Blk and BLK, is a member of theprotein kinase superfamily, Tyr protein kinase family and SRC subfamily. BLK / p55-Blk is expressed in lymphatic organs, pancreatic islets, Leydig cells, striate ducts of salivary glands and hair follicles. BLK / p55-Blk is a src-family protein tyrosine kinase specifically expressed in B-lineage cells of mice. The early onset of Blk expression during B-cell development in the bone marrow and... |
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TMPY-04411
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YES1 Protein, Human, Recombinant (His & GST)
HsT441,c-yes,YES proto-oncogene 1, Src family tyros...
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Human
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Baculovirus Insect Cells
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Proto-oncogene tyrosine-protein kinase Yes, also known as Proto-oncogene c-Yes, p61-Yes and YES1, is a cytoplasm protein that belongs to the protein kinase superfamily, Tyr protein kinase family and SRC subfamily. YES1 / c-Yes contains one protein kinase domain, one SH2 domain and one SH3 domain. It is thought that the subcellular distribution of Src-family tyrosine kinases, including c-Yes binding to the cellular membrane, is membranous and/or cytoplasmic. YES1 / c-Yes protein tyrosine kinase i... |
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TMPY-02519
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BLVRB Protein, Human, Recombinant (His)
HEL-S-10,biliverdin reductase B,FLR,BVRB,SDR43U1
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Human
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E. coli
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Biliverdin reductase (hBVR) is a serine/threonine kinase that catalyzes reduction of the heme oxygenase (HO) activity product, biliverdin, to bilirubin. BVR consists of an N-terminal dinucleotide-binding domain (Rossmann-fold) and a C-terminal domain that contains a six-stranded β-sheet that is flanked on one face by several α-helices. The C-terminal and N-terminal domains interact extensively, forming the active site cleft at their interface. Biliverdin reductase (BVR) catalyzes the last step i... |
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TMPY-04414
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MUSK Protein, Human, Recombinant (aa 433-783, His & GST)
FADS,CMS9,muscle, skeletal, receptor tyrosine kinas...
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Human
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Baculovirus Insect Cells
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Muscle, skeletal receptor tyrosine-protein kinase, also known as Muscle-specific tyrosine-protein kinase receptor, Muscle-specific kinase receptor, and MUSK, is a single-pass type I membrane protein that belongs to the protein kinase superfamily and tyr protein kinase family. MUSK contains one FZ (frizzled) domain, three Ig-like C2-type (immunoglobulin-like) domains, and one protein kinase domain. This protein is a muscle-specific tyrosine kinase receptor and it may play a role in clustering of ... |
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TMPH-02274
|
JAK2 Protein, Human, Recombinant (His)
JAK2,Janus kinase 2,Tyrosine-protein kinase JAK2
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Human
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E. coli
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Non-receptor tyrosine kinase involved in various processes such as cell growth, development, differentiation or histone modifications. Mediates essential signaling events in both innate and adaptive immunity. In the cytoplasm, plays a pivotal role in signal transduction via its association with type I receptors such as growth hormone (GHR), prolactin (PRLR), leptin (LEPR), erythropoietin (EPOR), thrombopoietin (THPO); or type II receptors including IFN-alpha, IFN-beta, IFN-gamma and multiple int... |
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