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Search Results for " txnrd1 "
Targets Recommended: Others

2

抑制剂 & 化合物

1

重组蛋白

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Cat. No. Product Name Target Signaling Pathways
T5481 TRi-1

Others Others
TRi-1 是不可逆的胞质硫氧还蛋白还原酶1 的特异性抑制剂(IC50:12 nM)。它有抗肿瘤作用,且线粒体毒性很小。
T60446 LCS3

Apoptosis; Glutathione reductase Apoptosis; oxidation-reduction
LCS3是一种可逆和非竞争性的谷胱甘肽二硫化物还原酶(GSR)和硫氧还蛋白还原酶1TXNRD1)的协同抑制剂,IC50分别为3.3μM 和3.8μM。LCS3具有抗肿瘤活性,可诱导细胞凋亡,可用于研究肺腺癌(LUAD)。

化合物

TRi-1
Cat.No: T5481
Synonym:
Target: Others
LCS3
Cat.No: T60446
Synonym:
Target: Apoptosis, Glutathione reductase
Cat. No. Product Name Species Expression System
TMPY-02271 TRXR1/TXNRD1 Protein, Human, Recombinant (aa 161-647, His)

thioredoxin reductase 1,TR1,TXNR,TR,TRXR

Human E. coli
Thioredoxin reductase 1 (TXNRD1) which is a selenocysteine-containing protein is overexpressed in many malignancies. TXNRD1 plays a key role in regulating cell growth and transformation, and protects cells against oxidative damage. We investigated the association between TXNRD1 polymorphisms and ATDH susceptibility. Moreover, TXNRD1 is an essential selenium-containing enzyme involved in detoxification of reactive oxygen species (ROS) and redox signaling. And genetic variations in TXNRD1 favor th...

重组蛋白

TRXR1/TXNRD1 Protein, Human, Recombinant (aa 161-647, His)
Cat.No: TMPY-02271
Species: Human
Expression System: E. coli
TargetMol Loading
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