190
29
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Cat. No. | Product Name | ||
---|---|---|---|
L1110 | 微管靶向化合物库 | 142 compounds | |
142 种靶向微管的分子集合,用于高通量筛选和高内涵筛选; |
Cat. No. | Product Name | Form | Specificity Of Inhibition |
---|---|---|---|
C0004 |
Phosphatase Inhibitor Cocktail III (2 Tubes, 100x)
磷酸酶抑制剂 Cocktail III (2 Tubes, 100x) |
2 <em>Tub</em>e Solution (100×) | Each <em>Tub</em>e has different specificity of inhibition |
Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T9812 |
Tubulin inhibitor 24
|
Microtubule Associated | Cytoskeletal Signaling |
Tubulin inhibitor 24 是一种 tubulin 抑制剂,可以抑制微管蛋白聚合,以浓度依赖性方式诱导细胞周期停滞在 G2/M 期, 具有抗肿瘤活性且无明显毒性。 | |||
T6161 |
Tubastatin A Hydrochloride
TSA HCl,Tubastatin A HCl |
Apoptosis; HDAC; Autophagy | Apoptosis; Autophagy; Chromatin/Epigenetic; DNA Damage/DNA Repair |
Tubastatin A Hydrochloride (TSA HCl) 是一种选择性的 HDAC6抑制剂,IC50值为 15 nM,对其选择性是 HDAC8 外的其他亚型的 1000 多倍。 | |||
T6745 |
5-Iodotubercidin
5-碘代杀结核菌素,5-ITu,NSC 113939 |
Adenosine Receptor | GPCR/G Protein; Neuroscience |
5-Iodotubercidin (NSC-113939) 是一种 ATP 类似物,有效抑制腺苷激酶,IC50为 26 nM。它可以激活磷酸化酶和糖原合成酶,在离体肝细胞中启动糖原合成。它也抑制 CK1、胰岛素受体酪氨酸激酶、磷酸化酶激酶、PKA、CK2、PKC 和 Haspin 。 | |||
T67753 |
Trifluoromethyl-tubercidin
|
Influenza Virus | Microbiology/Virology |
Trifluoromethyl-tubercidin (TFMT)可抑制宿主Mtr1并抑制病毒复制。TFMT 通过其S-adenosyl-l-methionine 结合袋相互作用抑制Mtr1,限制流感病毒复制。TFMT 能有效抑制病毒在小鼠体内的复制,毒性很小。 | |||
T78701 |
Tubulin inhibitor 32
|
Apoptosis | Apoptosis |
Tubulin inhibitor 32是一种口服活性的新型微管抑制剂,具有抗增殖和抗肿瘤活性,可抑制微管聚合,可诱导细胞凋亡及在G2/M期引起细胞周期停滞。 | |||
T9995 |
Antituberculosis agent-5
|
Others | Others |
Antituberculosis agent-5是一种用于高通量测定的小分子。 | |||
T77647 |
Tubulin polymerization-IN-43
|
Apoptosis; Microtubule Associated | Apoptosis; Cytoskeletal Signaling |
Tubulin polymerization-IN-43 是一种微管蛋白聚合 (tubulin polymerization) 抑制剂。Tubulin polymerization-IN-43 具有多种作用,通过靶向 Colchicine 位点破坏细胞微管网络,促进白血病细胞的细胞周期停滞在 G2/M 期和细胞凋亡 (apoptosis)。Tubulin polymerization-IN-43 具有抗血管生成活性。 | |||
T29023 |
Tubastatin
|
Others | Others |
Tubastatin TFA salt is a highly potent, selective inhibitor of HDAC6. | |||
T9747 |
Antitubercular agent-30
|
Others | Others |
Antitubercular agent-30 具有抗结核活性。 | |||
T13226 |
Tubulin inhibitor 8
|
Microtubule Associated | Cytoskeletal Signaling |
Tubulin inhibitor 8是管蛋白和多种癌症细胞系的抑制剂,对管蛋白聚合和K562细胞生长具有抑制作用 ,IC50分别为0.73μM 和14nM。 | |||
T67935 |
Tubulin inhibitor 11
|
Apoptosis; Microtubule Associated | Apoptosis; Cytoskeletal Signaling |
Tubulin inhibitor 11 是一种口服活性的有效微管蛋白抑制剂。它通过靶向秋水仙碱结合位点,抑制tubulin聚合,进而促进有丝分裂阻断和apoptosis。 | |||
T72784 |
OTUB1/USP8-IN-1
|
DUB | Cell Cycle/Checkpoint; DNA Damage/DNA Repair; Ubiquitination |
OTUB1/USP8-IN-1 是一种高效的 OTUB1/USP8 抑制剂,具有潜在的抗癌活性,对 OTUB1 和 USP8 的 IC50 值分别为 0.17 和 0.28 nM。OTUB1/USP8-IN-1 可用于研究非小细胞肺癌。 | |||
T77728 |
Tubulin polymerization-IN-55
|
Microtubule Associated | Cytoskeletal Signaling |
Tubulin polymerization-IN-55 是一种高效的 Tubulin Polymerization 抑制剂,具有潜在的抗血管生成和抗肿瘤活性,对 A549、K562、HepG2、MDA-MB-231 和 HFL-1 显示出抗增殖作用。 | |||
T1966 |
Tubastatin A
Tubastatin A BASE |
Apoptosis; HDAC; Autophagy | Apoptosis; Autophagy; Chromatin/Epigenetic; DNA Damage/DNA Repair |
Tubastatin A (Tubastatin A BASE) 是一种选择性 HDAC6抑制剂,IC50值为 15 nM。 | |||
T77584 |
Tubulin inhibitor 35
Tubulin IN 35 |
Apoptosis; Microtubule Associated; Topoisomerase | Apoptosis; Cytoskeletal Signaling; DNA Damage/DNA Repair |
Tubulin inhibitor 35 (Tubulin IN 35) 是一种有效的拓扑异构酶 I 和微管蛋白聚合 的双重抑制剂,具有抗肿瘤活性,对 MGC-803 和 RKO 细胞株的迁移和侵袭有抑制作用,中断细胞周期,诱导凋亡 (apoptosis)。 | |||
T13224 |
Tubulin inhibitor 6
iHAP1 |
Microtubule Associated | Cytoskeletal Signaling |
Tubulin inhibitor 6 (iHAP1) 是一种微管蛋白抑制剂,抑制微管蛋白聚合,IC50为 0.87 μM。它抑制多种癌细胞系,抑制 K562 细胞生长,IC50为 840 nM。 | |||
T60062 |
Antitubercular agent-41
|
Antibiotic | Microbiology/Virology |
Antitubercular agent-41是一种抗菌剂。 | |||
T6327 |
Tubacin
|
Virus Protease; HDAC | Chromatin/Epigenetic; DNA Damage/DNA Repair; Microbiology/Virology |
Tubacin 是一种高效、选择性、可逆、可渗透细胞的 HDAC6 抑制剂,IC50 为 4 nM,选择性是 HDAC1 的约 350 倍。 | |||
T77651 |
Tubulin polymerization-IN-47
|
Microtubule Associated | Cytoskeletal Signaling |
Tubulin polymerization-IN-47 是一种 tubulin 聚合抑制剂和有丝分裂抑制剂,具有抗肿瘤活性,对神经母细胞瘤癌细胞增殖具有抑制作用,对 Chp-134 和 Kelly 细胞系的IC50 分别为 7 和 12 nM。Tubulin polymerization-IN-47 是治疗肝癌、结肠癌、肺癌和乳腺癌的候选化合物。 | |||
TP1420 |
Microtubule-associated protein tau (26-44)
|
||
Microtubule-associated protein tau (26-44) is a synthetic peptide with an amino group conjugated to glutamine and a carboxyl group conjugated to lysine. | |||
T61252 |
Antitubercular agent-16
|
Others | Others |
Antitubercular agent-16 (Compound 5q) is a potent antitubercular agent exhibiting high efficacy against various strains of M. tuberculosis, including H37Rv, CF16, CF61, CF76, CF152, and CF161, with MIC 90 values ranging from 0.40 to 23.51 μg/mL. Notably, Antitubercular agent-16 demonstrates minimal cytotoxicity towards macrophages and pulmonary fibroblasts, further highlighting its potential as a therapeutic agent [1]. | |||
T62058 |
αβ-Tubulin-IN-1
|
Others | Others |
αβ-Tubulin-IN-1 是有效且具有口服活性的αβ-Tubulin 抑制剂。αβ-Tubulin-IN-1 将细胞周期阻滞在 G2/M 期并诱导细胞凋亡 (apoptosis)。αβ-Tubulin-IN-1 抑制肿瘤细胞迁移和转移。αβ-Tubulin-IN-1 具有显著的抗肿瘤功效。 | |||
T38298 |
Tuberculosis inhibitor 3
|
Others | Others |
Tuberculosis inhibitor 3 (compound 2i) displays potent anti-TB activity (MIC < 0.016 μg/mL) against drug-sensitive/resistant MTB strains. Tuberculosis inhibitor 3 (compound 2i) shows acceptable PK profiles with oral bioavailability[1]. | |||
T60735 |
Tubulin polymerization-IN-22
|
Others | Others |
Tubulin aggregation-IN-22 抑制细胞周期在 G2/M 期,并且诱导细胞凋亡。Tubulin aggregation-IN-22 是一种微管蛋白聚合抑制剂 (IC50 = 8.1 μM)。 | |||
T62642 |
Microtubule inhibitor 4
|
Others | Others |
Microtubule inhibitor 4 (compound 2) 是一种有效的 microtubule 抑制剂。Microtubule inhibitor 4 对 NCI-H460 (IC50s: 4.0 nM)、BxPC-3 (IC50s: 3.2 nM)、HT-29 (IC50s: 2.1 nM) 细胞具有细胞毒性。Microtubule inhibitor 4 能够抑制微管蛋白聚合。 | |||
T60971 |
Antitubercular agent-14
|
Others | Others |
Antitubercular agent-14 (Compound 1) 具有抗结核活性。Antitubercular agent-14 对结核分枝杆菌的 MIC 值为 0.3 μg/mL。 | |||
T61471 |
Antitubercular agent-13
|
Others | Others |
Antitubercular agent-13 (Compound 3d) 是一种抗结核剂,对 MTB H37Rv 和 MDR-MTB 16833 的 MIC 值分别为 0.007 μg/mL 和 1.851 μg/mL。Antitubercular agent-13 表现出代谢不稳定性。 | |||
T62332 |
Tubulin inhibitor 13
|
Others | Others |
Tubulin inhibitor 13 (E27) 是一种有效的tubulin抑制剂,其对tubulin聚合的抑制IC50值为16.1 μM。该化合物不仅可以抑制癌细胞迁移和侵袭,还能诱导apoptosis,显示出抗癌活性。 | |||
T61928 |
Antitubercular agent-25
|
Others | Others |
Antitubercular agent-25 (Compound 28) 是一种抗结核剂。Antitubercular agent-25抑制细胞外M. tuberculosisH37Rv 的IC50为 0.42 μM,细胞内为 0.20 μM。Antitubercular agent-25代谢稳定性良好。 | |||
T72503 |
Antitubulin agent 1
|
Others | Others |
Antitubulin agents-1 是一种抗微管蛋白剂,可诱导微管 (microtubules) (Microtubule/Tubulin) 破坏并增加 α-微管蛋白乙酰化。Antitubulin agents-1 具有抗癌作用。 | |||
T62639 |
Microtubule inhibitor 7
|
Others | Others |
化合物17o(IC50= 14.0 nM,NCI-H460)和 17p(IC50= 2.9 nM,NCI-H460)与呋喃基团对各种人类癌症细胞系显示出有效的纳摩尔水平的细胞毒活性。 | |||
T79509 |
Tuberculosis inhibitor 6
|
Others | Others |
Tuberculosis inhibitor 6 (compound 2c),作为3-甲氧基-2-苯基咪唑并[1,2-b]哒嗪衍生物,对结核分枝杆菌(MIC90≤1.66 μM)及海洋分枝杆菌(MIC90为2.65 μM)展示出显著的抑制活性。 | |||
T62369 |
Tubulin polymerization-IN-17
|
Others | Others |
Tubulin aggregation-IN-17 (compound 23g) 是一种 tubulin 聚合的有效抑制剂。Tubulin aggregation-IN-17 具有微管蛋白解聚作用,能够诱导细胞凋亡并抑制迁移。Tubulin aggregation-IN-17 具有潜力进行癌症疾病的研究。 | |||
T62040 |
Tubulin polymerization-IN-30
|
Others | Others |
Tubulin polymerization-IN-30 (compound 6e) 是有效的微管蛋白聚合 (Tubulin polymerization) 抑制剂,可破坏细胞内微管组织,将细胞周期阻滞在 G2/M 期。Tubulin polymerization-IN-30 对 HeLa、SGC-7901和A549 等肿瘤细胞系具有良好的抗肿瘤活性,其IC50分别为 0.403、 2.16和2.21 μM。 | |||
T64045 |
Antitubercular agent-20
|
Others | Others |
Antitubercular agent-20 是口服具有活力的抗结核剂。Antitubercular agent-20 对 MTB H37Rv 和 MDR-MTB 表现出良好的抗结核效果,其 MIC<0.016 μg/ml。在 BALB/c 小鼠中,Antitubercular agent-20 表现出较低的细胞毒性和较好的耐受性。 | |||
T63849 |
Tubulin polymerization-IN-34
|
Others | Others |
Tubulin polymerization-IN-34 是 [1,2] 恶唑异吲哚微管蛋白聚合的抑制剂,能够高度选择边缘区淋巴瘤 VL51 细胞系。 | |||
T125907 |
Tuberospironine A
|
Others | Others |
Tuberospironine A 是一种有用的有机化合物,可用于生命科学领域的相关研究,其产品编号为 T125907。 | |||
T61222 |
Antituberculosis agent-1
|
Others | Others |
Antituberculosis agent-1 (Compound 8a) 是一种抗结核剂,对 M. tuberculosisH37Rv 的 MIC 值为 3.84 μg/mL。 | |||
T60459 |
Tubulin inhibitor 15
|
Others | Others |
Tubulin inhibitor 15 是有效的微管蛋白抑制剂,具有抗增殖活性。Tubulin inhibitor 15 在 HepG2 细胞中表现出细胞毒性。 | |||
T60460 |
Tubulin inhibitor 16
|
Others | Others |
Tubulin inhibitor 16 是有效的微管蛋白抑制剂,具有抗增殖活性。Tubulin inhibitor 16 在 HepG2 细胞中表现出细胞毒性。 | |||
T72676 |
Tubulin/MMP-IN-1
|
Others | Others |
Tubulin/MMP-IN-1 是一种有效的tubulin 和MMP 抑制剂。Tubulin/MMP-IN-1具有研究癌症疾病的潜力。Tubulin/MMP-IN-1 抑制微管蛋白聚合,诱导细胞周期停滞在 G2/M 期,导致 HepG2 细胞产生反应性氧化应激 (ROS),并通过线粒体依赖性凋亡途径导致细胞凋亡[ 1]。 | |||
T61143 |
Antitubercular agent-18
|
Others | Others |
Antitubercular agent-18 (Compound 9a) 为抗结核剂,对M. tuberculosisH37Rv、Spec. 192、Spec 210 及 Spec. 800 的最小抑制浓度(MIC)值依次为2、2、2 及128 μg/ml,展现出对分支杆菌的高选择性抗菌活性。 | |||
T79532 |
Tubulin polymerization-IN-44
|
Others | Others |
Tubulin polymerization-IN-44 (7w)为具高效性的微管蛋白聚合抑制剂,其IC50为0.21 μM。该化合物可诱发G2/M期阻塞并触发癌细胞凋亡(apoptosis),适用于肿瘤研究。 | |||
T125604 |
Tuberonoid A
|
Others | Others |
Tuberonoid A 是一种有用的有机化合物,可用于生命科学领域的相关研究。其产品编号为 T125604,CAS号为 1709795-29-8。 | |||
T79512 |
Tuberculosis inhibitor 9
|
Others | Others |
Tuberculosis inhibitor 9 (compound 3d) 为具有高抗菌性的3-甲氧基-2-苯基咪唑并[1,2-b]哒嗪衍生物,其针对结核分枝杆菌和海洋分枝杆菌的最小抑菌浓度(MIC90)均为0.64 μM。 | |||
T79288 |
Antitubercular agent-38
|
Others | Others |
Antitubercula agent-38,一种具有效抗结核活性的口服苯并噻嗪酮(BTZ)衍生物,其特点为低心脏毒性和低细胞毒性。 | |||
T60936 |
Tubulin polymerization-IN-24
|
Others | Others |
Tubulin aggregation-IN-24 (compound HMBA) 是一种有效的微管蛋白聚合抑制剂,可提高 GTP 水解速率并抑制微管组装。Tubulin aggregation-IN-24 诱导细胞凋亡和细胞周期停滞在 G2/M 期。Tubulin aggregation-IN-24 抑制乳腺癌细胞 MCF-7 的增殖。 | |||
T62448 |
Microtubule inhibitor 6
|
Others | Others |
Microtubule inhibitor 6 (compound 17o) 是一种有效的微管抑制剂。Microtubule inhibitor 6 对 NCI-H460 细胞、BxPC-3 细胞、HT-29 细胞表现出细胞毒性,他们的 IC50 值分别为 14.0、6.6、7.0 nM。Microtubule inhibitor 6 能够有效抑制微管聚合。 | |||
T78761 |
Tubulin inhibitor 34
|
Others | Others |
Tubulin inhibitor 34 (compound b5) 为抗癌效果显著之化学药物,能够阻断微管蛋白(tubulin)聚合,促使G2/M期细胞周期停滞及细胞凋亡(apoptosis),并展现出明显的抗血管生成与抗肿瘤活性。 | |||
T61023 |
Antitubercular agent-21
|
Others | Others |
Antitubercular agent-21 (Compound 15) 是具有低细胞毒性的抗结核剂。Antitubercular agent-21 对 M. tuberculosisH37Rv 的 MIC 值为 0.4 μg/mL。然而,Antitubercular agent-21 对其他微生物,如革兰氏阳性菌、革兰氏阴性菌或真菌,表现出较低的生物活性。 |
Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T5S0281 |
Tubuloside A
|
NOS | Immunology/Inflammation |
Tubuloside A 是一种苯乙醇苷,具有抗氧化活性和保肝活性。 | |||
T2715 |
Tubeimoside I
土贝母苷甲I,Tubeimoside-1,Lobatoside-H |
Apoptosis; Others | Apoptosis; Others |
Tubeimoside I (Tubeimoside-1) 是中药土贝母提取物,是一种抗肿瘤剂。 | |||
T7004 |
Tubercidin
结核菌素,杀结核菌素,Sparsomycin A,7-Deazaadenosine |
Influenza Virus; DNA/RNA Synthesis; Antibacterial; Antibiotic | Cell Cycle/Checkpoint; DNA Damage/DNA Repair; Microbiology/Virology |
Tubercidin (Sparsomycin A) 是从Streptomyces tubercidicus 得到的抗生素,抑制粪链球菌生长的IC50值为 0.02 μM。它是腺苷磷酸化酶的弱抑制剂,并干扰腺苷和 AMP 的磷酸化。它有抗病毒作用。 | |||
T6S0084 |
Tuberostemonine
对叶百部碱,Tuberstemonine |
Parasite | Microbiology/Virology |
Tuberostemonine (Tuberstemonine) 是一种生物碱,可作为抗疟疾剂,有较高的肠道通透性。 | |||
T4953 |
Neotuberostemonine
|
NOS | Immunology/Inflammation |
Neotuberostemonine 是一种结核分枝杆菌根中主要的止咳生物碱,能够阻碍巨噬细胞的募集和活化,从而减轻博来霉素 (Bleomycin) 诱导的肺纤维化。 | |||
T4S1849 |
Tubeimoside III
|
Others | Others |
Tubeimoside III 是一种具有抗炎和抗肿瘤活性的三萜皂苷,在体内具急性毒性。 | |||
T8852 |
tubuloside B
|
Apoptosis; Others | Apoptosis; Others |
Tubuloside B 是可从管花肉苁蓉茎中分离出的一种天然产物,具有抗氧化活性,可抑制TNFα 诱导的细胞凋亡。 | |||
T4S1848 |
Tubeimoside II
Tubeimoside-B,土贝母苷乙 |
Others | Others |
Tubeimoside II (Tubeimoside-B) 是一种齐墩果烷型三萜皂甙天然类似物,具有抗炎症和抗癌等生物特性。 | |||
TN4240 |
Hydroxytuberosone
|
Others | Others |
Hydroxytuberosone is a natural product from Pueraria lobata. | |||
TQ0112 |
Tubulysin A
TubA |
Microtubule Associated; ADC Cytotoxin | Antibody-drug Conjugate/ADC Related; Cytoskeletal Signaling |
Tubulysin A is a natural product from myxobacterial. It has many function in vitro assays, including anti-microtubule, anti-mitotic, an apoptosis inducer, anticancer, and anti-angiogenic. | |||
T13944 |
Tubulysin M
|
Others; ADC Cytotoxin | Antibody-drug Conjugate/ADC Related; Others |
Tubulysin M is a natural product isolated from the myxobacterial species Archangium geophyra and Angiococcus disciformis, and is a highly cytotoxic peptide. Tubulysin M is a cytotoxic activity tubulysin that inhibits tubulin polymerization and leads to ce | |||
T13941 |
Tubulysin G
|
Others; ADC Cytotoxin | Antibody-drug Conjugate/ADC Related; Others |
Tubulysin G is a natural product isolated from the myxobacterial species Archangium geophyra and Angiococcus disciformis, and is a highly cytotoxic peptide. Tubulysin G is a cytotoxic activity tubulysin that inhibits tubulin polymerization and leads to ce | |||
TN7507 |
(±)-Tuberonic Acid
12-hydroxy Jasmonic Acid |
Others | Others |
(±)-Tuberonic acid, a derivative of the plant growth regulator jasmonic acid, is present in M. oleifera. | |||
T13943 |
Tubulysin I
|
Others; ADC Cytotoxin | Antibody-drug Conjugate/ADC Related; Others |
Tubulysin I is a natural product isolated from the myxobacterial species Archangium geophyra and Angiococcus disciformis, and is a highly cytotoxic peptide. Tubulysin I is a cytotoxic activity tubulysin which inhibits tubulin polymerization and leads to c | |||
T13942 |
Tubulysin H
|
Others; ADC Cytotoxin | Antibody-drug Conjugate/ADC Related; Others |
Tubulysin H is a natural product isolated from the myxobacterial species Archangium geophyra and Angiococcus disciformis, and is a highly cytotoxic peptide. Tubulysin H is a cytotoxic activity tubulysin that inhibits tubulin polymerization and leads to ce | |||
TN1155 |
Corytuberine
|
Others | Others |
Corytuberine 具有促惊厥作用。 Corytuberine 的抗跳作用仅被纳洛酮抑制。 | |||
TN5192 |
Tuberosin
|
NOS; Glucokinase | Immunology/Inflammation; Metabolism |
Tuberosin shows anti-inflammatory and antioxidant activities.It demonstrated a significantly potent inhibition on yeast α-glucosidase in a dose dependent manner. | |||
T13940 |
Tubulysin F
|
Others; ADC Cytotoxin | Antibody-drug Conjugate/ADC Related; Others |
Tubulysin F is a natural product isolated from the myxobacterial species Archangium geophyra and Angiococcus disciformis, and is a highly cytotoxic peptide. Tubulysin F is a cytotoxic activity tubulysin that inhibits tubulin polymerization and leads to ce | |||
T13228 |
Tubulysin D
|
Microtubule Associated; ADC Cytotoxin | Antibody-drug Conjugate/ADC Related; Cytoskeletal Signaling |
Tubulysin D is a tetrapeptide isolated from the myxobacterial species Archangium geophyra and Angiococcus disciformis, and displays potent antitumor activity. | |||
TN5193 |
Tubotaiwine
|
AChR | Neuroscience |
Tubotaiwine shows selective activity against L. infantum. Tubotaiwine and apparicine have affinity for adenosine receptors in the micromolar range and also have in-vivo analgesic activity in mice. | |||
TN3519 |
Bisdehydroneotuberostemonine
|
Others | Others |
Bisdehydroneotuberostemonine shows significant inhibitory effect on lipopolysaccharide-induced nitric oxide production in BV2 microglia at 100 uM. | |||
T81194 |
Schibitubin I
|
||
Schibitubin I,一种从Schisandra bicolor var. tuberculata果实中分离得到的木质素,具有神经保护活性。 | |||
T13939 |
Tubulysin E
|
Others; ADC Cytotoxin | Antibody-drug Conjugate/ADC Related; Others |
Tubulysin E is a natural product isolated from the myxobacterial species Archangium geophyra and Angiococcus disciformis, and is a highly cytotoxic peptide. | |||
TN6583 | Cistantubuloside C1 | ||
Cistantubuloside C1 是一种天然产物,可用于生命科学领域的相关研究。其产品编号为 TN6583,CAS号为 620632-36-2。 | |||
TN3421 |
Anhydrotuberosin
|
Others | Others |
Anhydrotuberosin是一种天然产物,属于豆科葛属,其产品编号为 TN3421,CAS号为 41347-49-3。Anhydrotuberosin可用作对照参考。 | |||
TN4647 |
Neotuberostemonone
|
Others | Others |
Neotuberostemonone is a natural product from Stemona mairei. | |||
TN6303 |
Tuberculatin
|
||
Tuberculatin 是一种天然产物,可用于生命科学领域的相关研究。其产品编号为 TN6303,CAS号为 90706-10-8。 | |||
TN7328 |
Secotubeimoside I
|
Others | Others |
Secotubeimoside I is a tubeimoside I analogue and can be used as a standard reference. | |||
T13938 |
Tubulysin C
|
Others; ADC Cytotoxin | Antibody-drug Conjugate/ADC Related; Others |
Tubulysin C is a natural product isolated from the myxobacterial species Archangium geophyra and Angiococcus disciformis, and is a highly cytotoxic peptide. |
Cat. No. | Product Name | Species | Expression System |
---|---|---|---|
TMPK-00895 |
Tubby Protein, Human, Recombinant (His)
TUB,RD5,RDOB |
Human | E. coli |
Tubby is the founding member of the tubby-like family of proteins. Tubby-like proteins (TLPs) possess a highly conserved closed β barrel tubby domain at C-terminal and N-terminal F-box.Tubby plays a critical role in trafficking select GPCRs to the cilia. | |||
TMPY-02214 |
OTUB1 Protein, Human, Recombinant (His)
OTU deubiquitinase, ubiquitin aldehyde binding 1,OTB1,HSPC26... |
Human | E. coli |
Ubiquitin thioesterase OTUB1, also known as Deubiquitinating enzyme OTUB1, OTU domain-containing ubiquitin aldehyde-binding protein 1, Otubain-1, Ubiquitin-specific-processing protease OTUB1, OTUB1 and OTB1, is a cytoplasm protein that belongs to the peptidase C65 family. OTUB1 is a hydrolase that can remove conjugated ubiquitin from proteins and plays an important regulatory role at the level of protein turnover by preventing degradation. OTUB1 is a regulator of T-cell anergy, a phenomenon that... | |||
TMPH-03006 |
Ag85B Protein, Mycobacterium tuberculosis, Recombinant (His)
30 kDa extracellular protein,Diacylglycerol acyltransferase/... |
Mycobacterium tuberculosis | P. pastoris (Yeast) |
Ag85B Protein, Mycobacterium tuberculosis, Recombinant (His) is expressed in yeast with N-6xHis tag. The predicted molecular weight is 32.7 kDa and the accession number is P9WQP0. | |||
TMPH-03005 |
Ag85B Protein, Mycobacterium tuberculosis, Recombinant (E. coli, His)
30 kDa extracellular protein,DGAT,Fbps B,Diacylglycerol acyl... |
Mycobacterium tuberculosis | E. coli |
Ag85B Protein, Mycobacterium tuberculosis, Recombinant (E. coli, His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 36.2 kDa and the accession number is P9WQP0. | |||
TMPH-03009 |
EsxB Protein, Mycobacterium tuberculosis, Recombinant (E. coli, His)
ESAT-6-like protein EsxB,esxB,10 kDa culture filtrate antige... |
Mycobacterium tuberculosis | E. coli |
A secreted protein. Acts as a strong host T-cell antigen. Involved in translocation of bacteria from the host (human) phagolysosome to the host cytoplasm. Might serve as a chaperone to prevent uncontrolled membrane lysis by its partner EsxA. EsxB Protein, Mycobacterium tuberculosis, Recombinant (E. coli, His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 14.7 kDa and the accession number is P9WNK4. | |||
TMPH-02262 |
TUBB3 Protein, Human, Recombinant (GST)
Tubulin beta-III,Tubulin beta-3 chain,... |
Human | E. coli |
TUBB3 Protein, Human, Recombinant (GST) is expressed in E. coli expression system with N-GST tag. The predicted molecular weight is 50.1 kDa and the accession number is Q13509. | |||
TMPH-03014 |
MPT63 Protein, Mycobacterium tuberculosis, Recombinant (His)
mpt63,Antigen MPT63,16 kDa immunoprotective extracellular pr... |
Mycobacterium tuberculosis | E. coli |
N/A. MPT63 Protein, Mycobacterium tuberculosis, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 17.7 kDa and the accession number is P9WIP0. | |||
TMPH-03011 |
EsxH Protein, Mycobacterium tuberculosis, Recombinant (His & SUMO)
Low molecular weight protein antigen 7,esxH,10 kDa antigen C... |
Mycobacterium tuberculosis | E. coli |
EsxH, in complex with EsxG, disrupts ESCRT function and impairs host phagosome maturation, thereby promoting intracellular bacterial growth. The complex acts by interacting, via EsxH, with the host hepatocyte growth factor-regulated tyrosine kinase substrate (HGS/HRS), a component of the ESCRT machinery. | |||
TMPH-03013 |
HRP1 Protein, Mycobacterium tuberculosis, Recombinant (His & Myc & SUMO)
hrp1,Hypoxic response protein 1 |
Mycobacterium tuberculosis | E. coli |
Unlike some other CBS-domain containing proteins does not seem to bind AMP. | |||
TMPY-02522 |
OTUB2 Protein, Human, Recombinant (His)
OTU deubiquitinase, ubiquitin aldehyde binding 2,OTU2,OTB2,C... |
Human | E. coli |
Otubain 2 (OTUB2) is a member of DUBs that belong to the ovarian tumour (OTU) superfamily of proteins which consists of a five-stranded β-sheet sandwiched in between a small helical amino-terminal region consisting of α1 and α2, and a large helical region comprised of α3-α10. Like other DUBs, otubain 2 (OTUB2) cleaves proteins precisely at the ubiquitin-protein bond so that ubiquitylation process can be reversed and regulated. Otubain 2 (OTUB2)'s active-site cleft is sterically occluded by a nov... | |||
TMPJ-01386 |
STUB1 Protein, Human, Recombinant
Carboxy Terminus of Hsp70-Interacting Protein,STIP1 Homology... |
Human | E. coli |
E3 Ubiquitin-Protein Ligase CHIP is a cytoplasmic protein. CHIP is highly expressed in skeletal muscle, heart, pancreas, brain and placenta. CHIP interacts with the molecular chaperones Hsc70-Hsp70 and Hsp90 through its TPR domain; lead to in client substrate ubiquitylation and degradation by the proteasome. CHIP targets misfolded chaperone substrates towards proteasomal degradation. CHIP mediates transfer of non-canonical short ubiquitin chains to HSPA8 that have no effect on HSPA8 degradation.... | |||
TMPH-03008 |
ENR Protein, Mycobacterium tuberculosis, Recombinant (His)
FAS-II enoyl-ACP reductase,Enoyl-ACP reductase,Enoyl-[acyl-c... |
Mycobacterium tuberculosis | E. coli |
ENR Protein, Mycobacterium tuberculosis, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 32.6 kDa and the accession number is P9WGR0. | |||
TMPH-02993 |
DisA Protein, Mycobacterium paratuberculosis, Recombinant (His & Myc)
disA,c-di-AMP synthase,DNA integrity scanning protein DisA,D... |
Mycobacterium paratuberculosis | E. coli |
Participates in a DNA-damage check-point. DisA forms globular foci that rapidly scan along the chromosomes searching for lesions.; Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c-di-AMP likely acts as a signaling molecule that may couple DNA integrity with a cellular process. DisA Protein, Mycobacterium paratuberculosis, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predict... | |||
TMPH-03023 |
AmiB2 Protein, Mycobacterium tuberculosis, Recombinant (His & Myc & SUMO)
Putative amidase AmiB2 |
Mycobacterium tuberculosis | E. coli |
AmiB2 Protein, Mycobacterium tuberculosis, Recombinant (His & Myc & SUMO) is expressed in E. coli. | |||
TMPH-00383 |
Tubulin beta-1 chain Protein, Chicken, Recombinant (His)
Tubulin beta-1 chain,Beta-tubulin class-I |
Chicken | E. coli |
Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. Tubulin beta-1 chain Protein, Chicken, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 53.3 kDa and the accession number is P09203. | |||
TMPH-03612 |
SodC Protein, Mycobacterium tuberculosis, Recombinant (His & Myc)
Superoxide dismutase [Cu-Zn],sodC |
Mycobacterium tuberculosis | E. coli |
Destroys radicals which are normally produced within the cells and which are toxic to biological systems. May play a role in favoring mycobacterial survival in phagocytes. SodC Protein, Mycobacterium tuberculosis, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 28.1 kDa and the accession number is P9WGE8. | |||
TMPH-03010 |
EsxB Protein, Mycobacterium tuberculosis, Recombinant (His)
ESAT-6-like protein EsxB,10 kDa culture filtrate antigen CFP... |
Mycobacterium tuberculosis | P. pastoris (Yeast) |
A secreted protein. Acts as a strong host T-cell antigen. Involved in translocation of bacteria from the host (human) phagolysosome to the host cytoplasm. Might serve as a chaperone to prevent uncontrolled membrane lysis by its partner EsxA. | |||
TMPH-03022 |
PstP Protein, Mycobacterium tuberculosis, Recombinant
PP2C-family Ser/Thr phosphatase,pstP,Serine/threonine protei... |
Mycobacterium tuberculosis | E. coli |
Plays an important role in regulating cell division and growth by reversible phosphorylation signaling. May play important roles in regulating cellular metabolism and signaling pathways, which could mediate the growth and development of the cell. Plays a role in establishing and maintaining infection. PstP Protein, Mycobacterium tuberculosis, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 25.3 kDa and the accession number is P9WHW4. | |||
TMPJ-00773 |
TUBB4A Protein, Human, Recombinant (His)
Tubulin β-4A Chain,Tubulin 5 β,TUB |
Human | E. coli |
Tubulin Beta-4A Chain (TUBB4A) is a cytoplasmic peptide containing 444 amino acids. TUBB4A is a member of the Tubulin family. Tubulin is the major constituent of microtubules. Tubulin is a dimer composed of one alpha and one beta tubulin molecule; there are many forms of beta tubulins, Beta II and Beta IV Tubulin are ubiquitously expressed. Beta-III Tubulin, also known as Tubulin Beta-4, is regarded as a neuron-specific marker. It binds two moles of GTP, one at an exchangeable site on the beta c... | |||
TMPH-03017 |
CYP51 Protein, Mycobacterium tuberculosis, Recombinant (His & Myc)
Cytochrome P450-14DM,Sterol 14alpha-demethylase,Sterol 14-al... |
Mycobacterium tuberculosis | Baculovirus Insect Cells |
Its precise biological substrate is not known. Catalyzes C14-demethylation of lanosterol, 24,25-dihydrolanosterol and obtusifoliol which is critical for ergosterol biosynthesis. It transforms lanosterol into 4,4'-dimethyl cholesta-8,14,24-triene-3-beta-ol. | |||
TMPH-03004 |
Ag85A Protein, Mycobacterium tuberculosis, Recombinant (His)
Diacylglycerol acyltransferase/mycolyltransferase Ag85A,Fibr... |
Mycobacterium tuberculosis | E. coli |
Ag85A Protein, Mycobacterium tuberculosis, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 34.1 kDa and the accession number is P9WQP2. | |||
TMPH-03007 |
Ag85C Protein, Mycobacterium tuberculosis, Recombinant (His)
Acyl-CoA:diacylglycerol acyltransferase,Fibronectin-binding ... |
Mycobacterium tuberculosis | E. coli |
Ag85C Protein, Mycobacterium tuberculosis, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 36.1 kDa and the accession number is P9WQN8. | |||
TMPH-03016 |
MPT64 Protein, Mycobacterium tuberculosis, Recombinant (His)
Immunogenic protein MPT64,Antigen MPT64,mpt64 |
Mycobacterium tuberculosis | P. pastoris (Yeast) |
MPT64 Protein, Mycobacterium tuberculosis, Recombinant (His) is expressed in Yeast. | |||
TMPH-03021 |
PstP Protein, Mycobacterium tuberculosis, Recombinant (His)
Mycobacterial Ser/Thr phosphatase,PP2C-family Ser/Thr phosph... |
Mycobacterium tuberculosis | E. coli |
Plays an important role in regulating cell division and growth by reversible phosphorylation signaling. May play important roles in regulating cellular metabolism and signaling pathways, which could mediate the growth and development of the cell. Plays a role in establishing and maintaining infection. | |||
TMPH-03001 |
MT2731 Protein, Mycobacterium tuberculosis, Recombinant (His)
Antitoxin MT2731 |
Mycobacterium tuberculosis | P. pastoris (Yeast) |
Antitoxin component of a type II toxin-antitoxin (TA) system. Neutralizes the effect of cognate toxin MT2730. MT2731 Protein, Mycobacterium tuberculosis, Recombinant (His) is expressed in yeast with N-6xHis tag. The predicted molecular weight is 9.7 kDa and the accession number is P9WJ10. | |||
TMPH-03726 |
YscM Protein, Yersinia pseudotuberculosis serotype I, Recombinant (His & SUMO)
Yop proteins translocation protein M,Low calcium response lo... |
Yersinia pseudotuberculosis | E. coli |
Belongs to an operon involved in the translocation of Yop proteins across the bacterial membranes or in the specific control of this function. | |||
TMPH-03012 |
HBHA Protein, Mycobacterium tuberculosis, Recombinant (His & Myc)
Adhesin,Heparin-binding hemagglutinin,hbhA |
Mycobacterium tuberculosis | E. coli |
Required for extrapulmonary dissemination. Mediates adherence to epithelial cells by binding to sulfated glycoconjugates present at the surface of these cells. HBHA Protein, Mycobacterium tuberculosis, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 28.8 kDa and the accession number is P9WIP8. | |||
TMPY-03059 |
Tubulin cofactor A Protein, Human, Recombinant
tubulin folding cofactor A |
Human | E. coli |
Tubulin folding cofactor A belongs to the TBCA family. It is one of four proteins (cofactors A, D, E, and C) involved in the early step of the tubulin folding pathway. These proteins can fold intermediates and finally lead to correctly folded beta-tubulin. It is believed that tubulin folding cofactors A and D play a role in capturing and stabilizing beta-tubulin intermediates in a quasi-native confirmation. Tubulin folding cofactor E binds to the cofactor D/beta-tubulin complex; interaction with... | |||
TMPH-03003 |
Ag85A Protein, Mycobacterium tuberculosis, Recombinant (His & SUMO)
Diacylglycerol acyltransferase/mycolyltransferase Ag85A,Acyl... |
Mycobacterium tuberculosis | E. coli |
Ag85A Protein, Mycobacterium tuberculosis, Recombinant (His & SUMO) is expressed in E. coli expression system with N-6xHis-SUMO tag. The predicted molecular weight is 44.6 kDa and the accession number is P9WQP2. | |||
TMPH-03002 |
FtsQ Protein, Mycobacterium tuberculosis, Recombinant (His & Myc)
ftsQ,Cell division protein FtsQ |
Mycobacterium tuberculosis | E. coli |
Essential cell division protein. FtsQ Protein, Mycobacterium tuberculosis, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 28.2 kDa and the accession number is P9WNA0. | |||
TMPH-03018 |
MeTAP1 Protein, Mycobacterium tuberculosis, Recombinant (His)
Peptidase M,map-1,Methionine aminopeptidase 1 |
Mycobacterium tuberculosis | E. coli |
Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed. MeTAP1 Protein, Mycobacterium tuberculosis, Recombinant (His) is expressed in E. coli expression system with N-10xHis tag. The predicted molecular weight is 32.9 kDa and the accession ... | |||
TMPH-02995 |
MAP_1030 Protein, Mycobacterium paratuberculosis, Recombinant (His)
Probable transcriptional regulatory protein MAP_1030 |
Mycobacterium paratuberculosis | P. pastoris (Yeast) |
MAP_1030 Protein, Mycobacterium paratuberculosis, Recombinant (His) is expressed in yeast with N-6xHis tag. The predicted molecular weight is 28.8 kDa and the accession number is P62039. | |||
TMPH-03020 |
MTR Protein, Mycobacterium tuberculosis, Recombinant (His & Myc & SUMO)
mtr,Mycothione reductase,Mycothiol-disulfide reductase,NADPH... |
Mycobacterium tuberculosis | E. coli |
Catalyzes the NAD(P)H-dependent reduction of mycothione (the oxidized disulfide form of mycothiol) to mycothiol. | |||
TMPH-02409 |
LprG Protein, Mycobacterium tuberculosis, Recombinant (His & Myc)
27 kDa lipoprotein,lprG,Triacylglyceride transfer protein Lp... |
Mycobacterium tuberculosis | E. coli |
LprG Protein, Mycobacterium tuberculosis, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 29.2 kDa and the accession number is P9WK44. | |||
TMPH-03000 |
ATase Protein, Mycobacterium tuberculosis, Recombinant (His)
ATase,Glutamine phosphoribosylpyrophosphate amidotransferase... |
Mycobacterium tuberculosis | E. coli |
Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine. ATase Protein, Mycobacterium tuberculosis, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 56.5 kDa and the accession number is P9WHQ6. | |||
TMPH-03015 |
MPT64 Protein, Mycobacterium tuberculosis, Recombinant (E. coli, His)
mpt64,Antigen MPT64,Immunogenic protein MPT64 |
Mycobacterium tuberculosis | E. coli |
N/A. MPT64 Protein, Mycobacterium tuberculosis, Recombinant (E. coli, His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 26.4 kDa and the accession number is P9WIN9. | |||
TMPH-02994 |
MAP_1030 Protein, Mycobacterium paratuberculosis, Recombinant (E. coli, His)
Probable transcriptional regulatory protein MAP_1030 |
Mycobacterium paratuberculosis | E. coli |
MAP_1030 Protein, Mycobacterium paratuberculosis, Recombinant (E. coli, His) is expressed in E. coli expression system with N-10xHis tag. The predicted molecular weight is 32.8 kDa and the accession number is P62039. | |||
TMPH-00758 |
EspK Protein, Mycobacterium tuberculosis, Recombinant (His & Myc)
espK,ESX-1 secretion-associated protein EspK |
Mycobacterium tuberculosis | E. coli |
May act as a chaperone that facilitates EspB secretion through an interaction with EccCb1. | |||
TMPH-03019 |
MPT51 Protein, Mycobacterium tuberculosis, Recombinant (His & SUMO)
MPT51/MPB51 antigen,mpt51 |
Mycobacterium tuberculosis | E. coli |
May have a role in host tissue attachment, whereby ligands may include the serum protein fibronectin and small sugars. MPT51 Protein, Mycobacterium tuberculosis, Recombinant (His & SUMO) is expressed in E. coli expression system with N-6xHis-SUMO tag. The predicted molecular weight is 44.5 kDa and the accession number is P9WQN6. | |||
TMPH-02260 |
TUBB Protein, Human, Recombinant (His)
Tubulin beta chain,TUBB,Tubulin b... |
Human | E. coli |
Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. TUBB Protein, Human, Recombinant (His) is expressed in E. coli expression system with C-6xHis tag. The predicted molecular weight is 50.6 kDa and the accession number is P07437. | |||
TMPH-03196 |
PYCR Protein, Mycobacterium tuberculosis, Recombinant (His & Myc)
PCA reductase,Pyrroline-5-carboxylate reductase,proC |
Mycobacterium tuberculosis | E. coli |
Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline. PYCR Protein, Mycobacterium tuberculosis, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 37.6 kDa and the accession number is P9WHU7. | |||
TMPH-02261 |
TUBB2A Protein, Human, Recombinant (His)
TUBB2A,Tubulin beta-2A chain,Tubu... |
Human | P. pastoris (Yeast) |
Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. | |||
TMPH-02999 |
uL2 Protein, Mycobacterium tuberculosis, Recombinant (His)
rplB,50S ribosomal protein L2,Large ribosomal subunit protei... |
Mycobacterium tuberculosis | E. coli |
One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome. uL2 Protein, Mycobacterium tuberculosis, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 34.7 kDa and the accession ... | |||
TMPK-00709 |
Tulp1 Protein, Human, Recombinant (His)
LCA15,TUBL1,TULP1,RP14,Tubby-related prote... |
Human | E. coli |
The tubby-like protein 1 (tulp1) gene is a member of the tubby multigene family which includes tub, tulp1, tulp2 and tulp3.TULP1 is a cytoplasmic, membrane-associated protein shown to be involved in transportation of newly synthesized proteins destined for the outer segment compartment of photoreceptor cells. |