12
1
5
Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T2141 |
Mecamylamine hydrochloride
盐酸美加明,Inversine,Mevasin |
AChR | Neuroscience |
Mecamylamine hydrochloride (Mevasin) 是一种易穿过血脑屏障的烟碱拮抗剂,用作高血压的神经节阻滞剂,具有抗神经疾病作用。 | |||
T26357 |
Pitstop 2
|
Apoptosis | Apoptosis |
Pitstop2 是一种选择性的两性蛋白结合的网格蛋白末端结构域抑制剂,IC50 值为 12 μM。 Pitstop2 严重干扰受体介导的内吞作用、HIV 进入和突触小泡循环。 | |||
TP2222L |
APTSTAT3-9R acetate
|
STAT | JAK/STAT signaling; Stem Cells |
APTSTAT3-9R acetate 是一种特异性肽结合 STAT3,具有抗增殖和抗肿瘤活性。 APTSTAT3-9R acetate 并通过特异性阻断 STAT3 磷酸化来抑制 STAT3 活化和下游信号传导。 | |||
TP2222 |
APTSTAT3-9R
|
Others | Others |
APTSTAT3-9R-9R is a STAT3 inhibitor (Ki: 231 nmol/L). STAT3 has been reported to promote the proliferation, survival, metastasis, immune escape, as well as drug resistance of cancer cells, making it a promising target for various diseases. However, though | |||
T126527 |
Poststerone
|
Others | Others |
Poststerone 是一种有用的有机化合物,可用于生命科学领域的相关研究,其产品编号为 T126527。 | |||
T25256 |
Pitstop1
Clathrin inhibitor 1,Clathrin-inhibitor-1,Clathrin IN 1 |
Others | Others |
Clathrin-IN-1 is a selective clathrin inhibitor that acts by addressing clathrin function in cell physiology with potential applications as an inhibitor of virus and pathogen entry and as a modulator of cell signaling. | |||
TP2421 |
Ysdspstst peptide
|
||
Ysdspstst peptide is a biochemical. | |||
T25973 |
Poststatin
|
Others | Others |
Poststatin is a prolyl endopeptidase inhibitor produced by Streptomyces viridochromogenes MH534-30F3. | |||
T34055 |
Phtstllap
|
Others | Others |
Phtstllap is a luteinizing hormone-releasing factor | |||
T61625 |
GABAA receptor agonist 2
|
Others | Others |
GABAA receptor agonist 2 (compound 4c) is a highly potent GABAA receptor agonist which exhibits anti-depressive properties in classical mouse models of depression, such as the FST and TST. By binding to the GABA binding site on the GABAA receptor, GABAA receptor agonist 2 produces GABAergic effects. Notably, Compound 4c holds promise for depression research [1]. | |||
T60842 |
GABAA receptor agonist 1
|
Others | Others |
GABAA receptor agonist 1 (compound 3e) 是有效的 GABAA 受体激动剂,它结合在GABAA 受体的 GABAA 结合位点结合以产生 GABA 能效应。GABAA receptor agonist 1 在 FST 和 TST 抑郁症的经典小鼠模型中具有抗抑郁活性,在抑郁症研究中具有潜力。 | |||
T65440 |
Sodium Thiosulfate Pentahydrate
|
Others | Others |
Sodium thiosulfate (Pentahydrate) is an antioxidant and antifungal. Sodium thiosulfate protects against cisplatin-induced hearing loss in children and is not associated with serious adverse events attributed to its use[3]. The addition of sodium thiosulfate, administered 6 hours after cisplatin chemotherapy, resulted in a lower incidence of cisplatin-induced hearing loss among children with standard-risk hepatoblastoma, without jeopardizing overall or event-free survival[4]. Calciphylaxis is a p... |
Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T11218 |
ε-Viniferin
epsilon-Viniferin,Epsilon-白藜芦醇脱氢二聚体 |
P450 | Metabolism |
ε-Viniferin (epsilon-Viniferin) 提取自 Vitis vinifera,是 Resveratrol 的二聚体,能够抑制 CYP 家族,其 Ki=0.5~20 μM,具有抗氧化作用。 |
Cat. No. | Product Name | Species | Expression System |
---|---|---|---|
TMPH-03579 |
TSST-1 Protein, S. aureus, Recombinant (His & SUMO)
Toxic shock syndrome toxin-1,tst |
Staphylococcus aureus | E. coli |
Responsible for the symptoms of toxic shock syndrome. TSST-1 Protein, S. aureus, Recombinant (His & SUMO) is expressed in E. coli expression system with N-6xHis-SUMO tag. The predicted molecular weight is 37.9 kDa and the accession number is P06886. | |||
TMPK-01481 |
HLA-A*24:02&B2M&Survivin 2B (AYACNTSTL) Monomer Protein, Human, MHC (His & Avi), Biotinylated
svn 2B,svn-2B,Survivin-2B |
Human | HEK293 Cells |
Survivin-2B, a known splice variant of survivin, has been reported to promote cell death in some cancer cells, although it keeps prosurvival function in others.survivin-2B promoted autophagy and further regulated cell death by accumulating and stabilizing IKK alpha in the nucleus. | |||
TMPJ-01111 |
TSTA3 Protein, Human, Recombinant (His)
GDP-L-Fucose Synthase,Short-Chain Dehydrogenase/Reductase Fa... |
Human | E. coli |
GDP-L-Fucose Synthase is a NADP(H)-binding protein. It catalyzes the two-step epimerase and the reductase reactions in GDP-D-mannose metabolism, converting GDP-4-keto-6-D-dexoymannose to GDP-L-fucose. GDP-L-Fucose is the substrate of several fucosyltransferase, involving the expression of mamy glycoconjugates, including blood group ABH antigens and development adhesion antigens. Mutations in the TSTA3 gene may cause leukocyte adhesion deficiency type II. | |||
TMPK-01486 |
HLA-A*24:02&B2M&Survivin 2B (AYACNTSTL) Tetramer Protein, Human, MHC (His & Avi)
svn-2B,Survivin-2B,svn 2B |
Human | HEK293 Cells |
Survivin-2B, a known splice variant of survivin, has been reported to promote cell death in some cancer cells, although it keeps prosurvival function in others.survivin-2B promoted autophagy and further regulated cell death by accumulating and stabilizing IKK alpha in the nucleus. | |||
TMPK-01487 |
HLA-A*24:02&B2M&Survivin 2B (AYACNTSTL) Monomer Protein, Human, MHC (His & Avi)
svn-2B,Survivin-2B,svn 2B |
Human | HEK293 Cells |
Survivin-2B, a known splice variant of survivin, has been reported to promote cell death in some cancer cells, although it keeps prosurvival function in others.survivin-2B promoted autophagy and further regulated cell death by accumulating and stabilizing IKK alpha in the nucleus. |