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Search Results for " trim24 "
Targets Recommended: Others

6

抑制剂 & 化合物

1

重组蛋白

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Cat. No. Product Name Target Signaling Pathways
T74271 TRIM24/BRPF1-IN-2

Others Others
TRIM24/BRPF1-IN-2 (compound 20l) 是一种有效的 TRIM24/BRPF1双重抑制剂,IC50值分别为 0.98 和 1.16 μM。 TRIM24/BRPF1-IN-2 显示出 TRIM24/BRPF1 溴结构域结合亲和力。 TRIM24/BRPF1-IN-2 可用于前列腺癌研究。
T15178 dTRIM24

Others; PROTACs Others; PROTAC
dTRIM24 是一种基于 PROTAC 技术的选择性双功能 TRIM24 降解剂,由von Hippel-Lindau 和TRIM24 两者配体构成。
T2127 OF-1

Epigenetic Reader Domain Chromatin/Epigenetic
OF-1 是溴结构域的一种抑制剂,其对TRIM24 和BRPF1B 的IC50值分别为270 mM 和1.2 μM。
T11597 IACS-9571

ASIS-P040

Epigenetic Reader Domain Chromatin/Epigenetic
IACS-9571 is a selective and potent inhibitor of TRIM24 and BRPF1, (IC50: 8 nM for TRIM24; Kds: 31 nM and 14 nM for TRIM24 and BRPF1).
T11597L IACS-9571 Hydrochloride (1800477-30-8 free base)

IACS-9571 Hydrochloride,ASIS-P040 Hydrochloride

Epigenetic Reader Domain Chromatin/Epigenetic
IACS-9571 Hydrochloride is a selective and potent inhibitor of TRIM24 and BRPF1, (IC50: 8 nM for TRIM24; Kds: 31 nM and 14 nM for TRIM24 and BRPF1).
T72274 IACS-9571 hydrochloride

ASIS-P040 hydrochloride

Others Others
IACS-9571 (ASIS-P040) hydrochloride 是溴结构域蛋白 TRIM24和 BRPF1的抑制剂,对 TRIM24 的 IC50和 Kd 值分别为 8 nM 和 31 nM,对 BRPF1的 Kd 值为 14 nM。

化合物

TRIM24/BRPF1-IN-2
Cat.No: T74271
Synonym:
Target: Others
dTRIM24
Cat.No: T15178
Synonym:
Target: Others, PROTACs
OF-1
Cat.No: T2127
Synonym:
Target: Epigenetic Reader Domain
IACS-9571
Cat.No: T11597
Synonym: ASIS-P040
Target: Epigenetic Reader Domain
IACS-9571 Hydrochloride (1800477-30-8 free base)
Cat.No: T11597L
Synonym: IACS-9571 Hydrochloride,ASIS-P040 Hydrochloride
Target: Epigenetic Reader Domain
IACS-9571 hydrochloride
Cat.No: T72274
Synonym: ASIS-P040 hydrochloride
Target: Others
Cat. No. Product Name Species Expression System
TMPH-02221 TRIM24 Protein, Human, Recombinant (His & SUMO)

Transcription intermediary factor 1-alpha,E3 ubiquitin-prote...

Human E. coli
Transcriptional coactivator that interacts with numerous nuclear receptors and coactivators and modulates the transcription of target genes. Interacts with chromatin depending on histone H3 modifications, having the highest affinity for histone H3 that is both unmodified at 'Lys-4' (H3K4me0) and acetylated at 'Lys-23' (H3K23ac). Has E3 protein-ubiquitin ligase activity. Promotes ubiquitination and proteasomal degradation of p53/TP53. Plays a role in the regulation of cell proliferation and apopt...

重组蛋白

TRIM24 Protein, Human, Recombinant (His & SUMO)
Cat.No: TMPH-02221
Species: Human
Expression System: E. coli
TargetMol Loading
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