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156
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Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T28996 |
TP-064
TP 064 |
Histone Methyltransferase | Chromatin/Epigenetic |
TP-064 是选择性蛋白精氨酸甲基转移酶 4 抑制剂 ,IC50小于10 nM,具有抗癌活性。它抑制 BAF155 和 MED12 的二甲基化,IC50为 340 和 43 nM。它对于 PRMT6 的 IC50为 1.3 μM。 | |||
T9250 |
TP-4748
|
Others | Others |
TP-4748 是一种生化物质。 | |||
T22440 |
TP-353
EOS-61973 |
CDK | Cell Cycle/Checkpoint |
TP-353 (EOS-61973) 是一种 CDK7 抑制剂。 | |||
T4523 |
TP-3654
|
Pim | Chromatin/Epigenetic; JAK/STAT signaling |
TP3654是一种Pim 激酶抑制剂,对Pim-1和Pim-3的Ki 值分别为5和42 nM。 | |||
T9254 |
TP-2857
TAP2857 |
Antibacterial | Microbiology/Virology |
TP-2857 (TAP2857) 是一种有效的抗菌剂。 | |||
T13189 |
TP-10
|
PDE | Metabolism |
TP-10 是 PDE10A 对其他 PDE 的特异性抑制剂,IC50 为 0.8 nM。 | |||
T24897 |
TP0427736
TP427736,TP-0427736,TP-427736 |
TGF-beta/Smad | Stem Cells |
TP0427736 是一种有效的选择性 ALK5 抑制剂,IC50 为 2.72 nM,比对 ALK3 的抑制作用高 300 倍。 TP0427736 可降低人外根鞘细胞中 TGF-β 诱导的生长抑制,并延长小鼠毛囊中的生长期。 | |||
T2469 |
TP808
TP-808,TP 808 |
Others | Others |
TP808是一种高度通用的中间体,可用于多种四环素类抗生素的构建。 | |||
T11227L |
Eravacycline dihydrochloride
TP-434-046,TP-434 dihydrochloride |
Antibacterial | Microbiology/Virology |
Eravacycline dihydrochloride (TP-434-046) 是一种有效的广谱抗菌剂,可对抗六种大肠杆菌(MIC:0.125-0.25 mg/L)。 | |||
T62525 |
TP-16
|
Prostaglandin Receptor | GPCR/G Protein; Immunology/Inflammation |
TP-16是一种新型高效且具有选择性的 EP4 拮抗剂,可阻断IMCs的功能,增强细胞毒性T细胞介导的体内肿瘤消除。 | |||
T34907 |
TP-238
TP 238 |
Others | Others |
TP-238 是一种有效的,选择性的CECR2/BPTF 双重探针,IC50值分别为 30 nM 和 350 nM。TP-238 还抑制BRD9,pIC50为 5.9,并且对其他 338 激酶的活性较低。 | |||
T28998 |
TP-680
TP 680 |
Others | Others |
TP-680 is a antagonist of cholecystokininA receptor. | |||
T24896 |
TP 9201
TP-9201,TP9201 |
Others | Others |
TP 9201 is a platelet integrin alphaIIbbeta3 antagonist. It is a synthetic RGD-containing cyclic peptide. | |||
T39486 |
TP-472N
|
Others | Others |
TP-472N serves as a negative control probe for TP-472, which is a specific and effective BRD7/9 probe. | |||
T23466 |
TP003
|
GABA Receptor | Membrane transporter/Ion channel; Neuroscience |
TP003是一种新型的非选择性GABAA 受体苯二氮卓位点激动剂,对α1β2γ2、α2β3γ2、α3β3γ2、α5β2γ2 的具有亲和力,其EC50 分别20.3、10.6、3.24、5.64 nM。 TP003 通过 α2GABAA 受体从而具有抗焦虑活性,也有部分抗惊厥活性。 | |||
T41110 |
EFdA-TP
|
Others | Others |
EFdA-TP, a highly potent nucleoside reverse transcriptase (RT) inhibitor, exerts its inhibitory effect on RT-catalyzed DNA synthesis through both immediate and delayed chain termination mechanisms, commonly referred to as ICT and DCT, respectively. Additionally, EFdA-TP demonstrates its efficacy in inhibiting HIV-1 RT through multiple pathways. | |||
TQ0120 |
CDDO-Im
RTA-403,CDDO-Imidazolide,TP-235 |
Others; Ferroptosis; Nrf2; PPAR | Apoptosis; DNA Damage/DNA Repair; Immunology/Inflammation; Metabolism; Others |
CDDO-Im (TP-235) 是一种 Nrf2和 PPAR 的激活剂,对 PPARα 和 PPARγ 的 Ki 分别为232 nM 和 344 nM。 | |||
T68535 |
TP-051
|
Others | Others |
TP-051 is a FFAR1 agonist. | |||
T68869 |
TP-110
|
Others | Others |
TP-110 is a new proteasome inhibitor, which shows potent growth inhibition in various tumor cell lines. Treatment with TP-110 for 24 h in vitro induced apoptosis in multiple myeloma cell line RPMI8226. TP-110 reduced the intrinsic inhibitor of apoptosis proteins (IAPs), cIAP-1 and XIAP, that suppress executioner caspases. | |||
T5392 |
TP0463518
|
HIF/HIF Prolyl-Hydroxylase | Chromatin/Epigenetic; Metabolism |
TP0463518 是缺氧诱导因子脯氨酰羟化酶抑制剂,能够作用于人 PHD2(Ki= 5.3 nM)。它还抑制人PHD1/PHD3,IC50分别为 18 和 63 nM,以及猴 PHD2(IC50=22 nM)。 | |||
T41202 |
TP 472N
|
Others | Others |
TP 472N is a negative control forTP 472. Inactive against other bromodomains (>20μM against BRD9). | |||
T40120 |
FNC-TP
|
Others | Others |
FNC-TP, the intracellular active form of FNC, is a potent nucleoside reverse transcriptase inhibitor (NRTI) with broad-spectrum antiviral activity against HIV, HBV, and HCV. | |||
T2005 |
Dubermatinib
TP0903 |
Apoptosis; TAM Receptor | Apoptosis; Tyrosine Kinase/Adaptors |
Dubermatinib (TP0903) 是一种具有高效性和选择性的 Axl 受体酪氨酸激酶抑制剂,IC50值为27 nM。 | |||
T9318 |
TP0586532
|
Others | Others |
TP0586532 是有效的non-hydroxamate LpxC 抑制剂 (IC50=0.101 μM)。TP0586532具有低心血管风险的特点,对肺炎克雷伯菌有效,包括耐药菌株。 | |||
T34866 |
Thymocartin
Thymocartinum,TP 4,Thymopoietin II (32-35),RGH 0206 |
||
Thymocartin (RGH 0206) 是天然存在胸腺因子 (胸腺生成素) 的 32-35 片段。Thymocartin 可用于研究免疫缺陷病。 | |||
T13190 |
TP-472
|
Epigenetic Reader Domain | Chromatin/Epigenetic |
TP-472 is a selective inhibitor of BRD9 (Kd: 33 nM). | |||
T34908 |
TP-422
TP422 |
Others | Others |
TP-422 is a negative control for TP-238. | |||
T28997 |
TP-271
TP271 |
Others | Others |
TP-271, a tetracyclines antibiotic, is used potentially for the treatment of community-acquired bacterial pneumonia (CABP). | |||
T13188 |
TP-004
|
Others | Others |
TP-004 is a potent and reversible methionine aminopeptidase 2 (MetAP2) inhibitor (IC50: 6 nM). | |||
T11227L1 |
Eravacycline HCl
Eravacycline HCL(1207283-85-9 Free bse),TP-434 HCl |
Antibiotic | Microbiology/Virology |
Eravacycline HCl (TP-434 HCl) 是一种具有广谱抗菌活性的强效抗生素。 | |||
T35649 |
EFdA-TP tetraammonium
|
Others | Others |
EFdA-TP tetraammonium is an influential nucleoside reverse transcriptase (RT) inhibitor that effectively prevents RT-mediated DNA synthesis by acting as an immediate or delayed chain terminator (ICT or DCT). Additionally, EFdA-TP tetraammonium exhibits multiple mechanisms of inhibiting HIV-1 RT[1]. | |||
T70429 |
TP-6076
|
Others | Others |
TP-6076 is a fluorocycline antibiotic, inhibiting bacterial protein synthesis, exhibiting great antimicrobial activity against carbapenem-resistant A. baumannii. | |||
T40055 |
TP-238 hydrochloride
|
Others | Others |
TP-238 hydrochloride is a highly potent and selective dual CECR2/BPTF probe, demonstrating IC50 values of 30 nM and 350 nM, respectively. It additionally exerts inhibitory effects on BRD9, with a pIC50 value of 5.9, while displaying lower activity against 338 other kinases. | |||
T6165 |
Bardoxolone Methyl
RTA 402,CDDO Methyl ester,TP-155,甲基巴多索隆,NSC 713200 |
Apoptosis; IκB/IKK; Ferroptosis; Nrf2; Autophagy | Apoptosis; Autophagy; Immunology/Inflammation; NF-κB |
Bardoxolone Methyl (TP-155) 是一种合成的三萜类化合物,作为 Nrf2通路的激活剂和 NF-κB 途径的抑制剂,具有潜在的抗肿瘤和抗炎活性。 | |||
T13139 |
TP-008
TGFβRI-IN-2 |
Others | Others |
TGFβRI-IN-2 is a selective, potent and orally active inhibitor of (Activin-Like Kinase 5) ALK 5(pIC50 and pEC50 values of 7.6 and 6.63, respectively). | |||
T71979 |
TP-S1-68
|
Others | Others |
TP-S1-68 is a Type-I inhibitor of TIE-2. | |||
T20515 |
Selank
TP-7,TP7,TP 7 |
||
Selank is a synthetic analog of tuftsin. | |||
T19588 |
TP748
2-苄氧基恶唑 |
Others | Others |
TP748 是一种异恶唑,也是合成四环素的关键中间体。 | |||
T26301 |
Tyropeptin A-4
TP 101,TP-101,TP101 |
Others | Others |
Tyropeptin A-4 is used as a proteasome inhibitor. | |||
T11227 |
Eravacycline
TP-434 |
Antibacterial | Microbiology/Virology |
Eravacycline (TP-434) 是一种有效的广谱抗菌剂。 | |||
T29431 |
4'-Azidothymidine 5'-triphosphate
Adrt TP,Adrt-TP,AdrtTP |
Others | Others |
4'-Azidothymidine 5'-triphosphate exerts selectively action on both reverse transcriptase of human immunodeficiency virus type 1 and human DNA polymerases alpha and beta. | |||
T73491 |
TP-050
|
Others | Others |
TP-050 是一种口服有效的选择性 NMDAR 激动剂,抑制 GluN2A 和 GluN2D 的 EC50值分别为 0.51 μM 和 9.6 µM。TP-050 可穿过血脑屏障 (BBB)。TP-050 诱导海马区的长期增益效应 (LTP),增强神经元信号传输。 | |||
T39104 |
Itacnosertib
Itacnosertib,TP-0184 |
Others | Others |
Itacnosertib (TP-0184) is a chemical compound that acts as an inhibitor of JAK2, ACVR1 (ALK2), and ALK5, as indicated in WO2014151871. | |||
T26209 |
Splenotritin
TP 3,Thymopoietin tripeptide,TP3,TP-3 |
Others | Others |
Splenotritin is used as an antimicrobial peptide. | |||
T84696 |
Itacnosertib (hydrocholide)
TP-0184 (hydrocholide) |
Others | Others |
Itacnosertib hydrocholide为JAK2、ACVR1 (ALK2) 及ALK5的抑制剂。 | |||
T73374 |
TP-030-1
|
Others | Others |
TP-030-1 是 RIPK1的抑制剂。TP-030-1 抑制 hRIPK1 的 Ki 值为 3.9 nM,抑制 mRIPK1 的 IC50值为 4.2 μM。TP-030-1 可用于炎症性疾病和神经退行性疾病的研究。 | |||
T75351 |
TP-TRFS
|
Others | Others |
TP-TRFS 是高度选择性的一个硫氧还蛋白还原酶 (TrxR) 双光子荧光探针。 | |||
T63701 |
TP-5801
|
Others | Others |
TP-5801 是口服具有活力的非受体酪氨酸激酶 (TNK1) 抑制剂,IC50 值为 1.40 nM,具有抗肿瘤作用。 | |||
T77775 |
TP-1454
|
Others | Others |
TP-1454是一种针对PKM2的激活剂,其生化测定的AC50为10 Nm。它可通过作用于T调节细胞来调控肿瘤的免疫反应。 | |||
T6446L |
Clevudine triphosphate
L-FMAU-TP |
Others | Others |
Clevudine triphosphate is a TTP analog that is able to inhibit protein priming independently of the deoxynucleoside triphosphate substrate. |
Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T2598 |
Thymopentin
TP5,胸腺五肽 |
Estrogen/progestogen Receptor; Endogenous Metabolite | Endocrinology/Hormones; Metabolism |
Thymopentin (TP5) 是主要由胸腺皮质和髓质上皮细胞分泌的生物特性肽。它能促使自人类胚胎干细胞产生 T 细胞群。它是有效免疫调节剂,具有很短的血浆半衰期(30 秒)。 | |||
T1352 |
ATP disodium salt
Adenosine 5'-triphosphate disodium salt,三磷酸腺苷二钠,ATP,ATP disodium,腺苷-5'-三磷酸二钠盐,Adetide,Adenosine-Triphosphate,Disodium adenosine triphosphate |
P2X Receptor; Endogenous Metabolite | Membrane transporter/Ion channel; Metabolism; Neuroscience |
ATP disodium salt (Adenosine-Triphosphate) 是体内能量储存的重要物质,为代谢提供能量,同时在细胞中作为辅酶发挥作用。Adenosine 5'-triphosphate disodium salt 也是免疫和炎症中重要的内源性信号分子。 | |||
T38427 |
dUTP trisodium
2'-Deoxyuridine-5'-triphosphate trisodium salt,Deoxyuridine triphosphate |
DNA/RNA Synthesis | Cell Cycle/Checkpoint; DNA Damage/DNA Repair |
dUTP trisodium (Deoxyuridine triphosphate) 是在 5'-位具有三磷酸基团的脱氧尿苷磷酸盐,可用于 PCR。 | |||
T64980 |
ATP disodium trihydrate
Adenosine-5'-triphosphate disodium trihydrate |
Endogenous Metabolite | Metabolism |
ATP disodium trihydrate (Adenosine-5'-triphosphate disodium trihydrate) 是体内能量储存和代谢的重要物质,是免疫和炎症中重要的内源性信号分子,可为机体代谢提供能量,同时在细胞中作为辅酶发挥作用。 | |||
T2812 |
ATP disodium salt hydrate
ATP disodium,ATP disodium salt,Adenosine disodium triphosphate,三磷酸腺苷二钠盐 |
Others; Endogenous Metabolite | Metabolism; Others |
ATP disodium salt hydrate (Adenosine disodium triphosphate) 是体内能量储存和代谢的重要物质,为代谢提供能量,同时在细胞中作为辅酶发挥作用。同时,它是也是免疫和炎症中重要的内源性信号分子。 | |||
T20089 |
ATP
Atipi,ATP disodium salt hydrate,Triphosphoric acid adenosine ester,Ara-ATP,Triphosphaden,Adenosine triphosphate;Ara-ATP,Adenosine triphosphate |
Endogenous Metabolite | Metabolism |
ATP (Adenosine triphosphate) 可为细胞提供能量,参与整体能量平衡,维持细胞内稳态。ATP 可以通过与特异性嘌呤能受体的相互作用充当细胞外信号分子,以介导神经传递、炎症、细胞凋亡和骨重塑等多种过程。 | |||
T73073 |
PTP1B-IN-21
|
Others | Others |
PTP1B-IN-21 是蛋白酪氨酸磷酸酶 1B (PTP1B) 的选择性抑制剂 (IC50=1.56 μM),抑制力超出高度同源 T 细胞蛋白酪氨酸磷酸酶 (TCPTP;IC50>100 μM),PTP1B 是抑制 2 型糖尿病的重要靶点。 | |||
T40526 |
ATP dipotassium
腺苷三磷酸二钾盐,Adenosine5'-triphosphatedipotassium |
Others | Others |
ATP dipotassium (Adenosine 5'-triphosphate dipotassium) is a vital compound involved in energy storage and metabolism within living organisms. It plays a crucial role in supplying metabolic energy for driving pumps and acts as a coenzyme in cellular processes. Additionally, ATP dipotassium functions as a significant endogenous signaling molecule contributing to immunity and inflammation. | |||
T73072 |
PTP1B-IN-20
|
Others | Others |
PTP1B-IN-20 是蛋白酪氨酸磷酸酶 1B (PTP1B) 的选择性抑制剂 (IC50=1.05 μM),抑制力超出高度同源 T 细胞蛋白酪氨酸磷酸酶 (TCPTP;IC50=78.0 μM),PTP1B 是抑制 2 型糖尿病的重要靶点。 | |||
T10021 |
1-Methylxanthine
|
Endogenous Metabolite | Metabolism |
1-Methylxanthine 是咖啡因衍生物,是咖啡因和茶碱 (1,3-二甲基黄嘌呤,TP) 在人体尿代谢产物,能够提高肿瘤细胞的放射敏感性。 |
Cat. No. | Product Name | Species | Expression System |
---|---|---|---|
TMPY-01679 |
LCN1 Protein, Human, Recombinant (His)
TLC,MGC71975,TP,VEGP,Lipocalin 1,PMFA |
Human | HEK293 Cells |
Lipocalin-1, also known as Von Ebner gland protein, VEG protein, Tear Prealbumin, VEGP, Tear lipocalin, and LCN1 is a secreted protein that belongs to the calycin superfamily and Lipocalin family. Human Lipocalin-1 / VEGP was originally described as a major protein of human tear fluid, which was thought to be tear specific. Lipocalin-1 / VEGP is identical to lingual von Ebner's gland protein and is also produced in the prostate, nasal mucosa, and tracheal mucosa. Homologous proteins have been fo... | |||
TMPY-00122 |
DPP4/CD26 Protein, Human, Recombinant (His)
TP103,ADABP,CD26,ADCP2,DPPIV,dipeptidylpeptidase 4 |
Human | HEK293 Cells |
DPP4/CD26 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 86.3 kDa and the accession number is P27487. | |||
TMPH-02245 |
HADHB Protein, Human, Recombinant (GST)
HADHB,TP-beta,Trifunctional enzyme subunit beta, mi... |
Human | E. coli |
Mitochondrial trifunctional enzyme catalyzes the last three of the four reactions of the mitochondrial beta-oxidation pathway. The mitochondrial beta-oxidation pathway is the major energy-producing process in tissues and is performed through four consecutive reactions breaking down fatty acids into acetyl-CoA. Among the enzymes involved in this pathway, the trifunctional enzyme exhibits specificity for long-chain fatty acids. Mitochondrial trifunctional enzyme is a heterotetrameric complex compo... | |||
TMPY-01195 |
CD7 Protein, Human, Recombinant (His)
CD7 molecule,Tp40,GP40,TP41,LEU-9 |
Human | HEK293 Cells |
CD7 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 18 kDa and the accession number is P09564. | |||
TMPH-02949 |
HADHA Protein, Mouse, Recombinant (His & Myc)
Trifunctional enzyme subunit alpha, mitochondrial,TP |
Mouse | E. coli |
HADHA Protein, Mouse, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 52.1 kDa and the accession number is Q8BMS1. | |||
TMPH-02950 |
HADHB Protein, Mouse, Recombinant (His & Myc)
TP-beta,Trifunctional enzyme subunit beta, mitochon... |
Mouse | E. coli |
HADHB Protein, Mouse, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 54.6 kDa and the accession number is Q99JY0. | |||
TMPY-00778 |
DPP4/CD26 Protein, Human, Recombinant (hFc)
DPPIV,TP103,ADABP,CD26,ADCP2,dipeptidylpeptidase 4 |
Human | HEK293 Cells |
DPP4/CD26 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 112 kDa and the accession number is P27487. | |||
TMPY-00779 |
DPP4/CD26 Protein, Human, Recombinant
TP103,CD26,ADCP2,DPPIV,ADABP,dipeptidylpeptidase 4 |
Human | HEK293 Cells |
DPP4/CD26 Protein, Human, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 85.4 kDa and the accession number is P27487. | |||
TMPJ-00960 |
TMPO Protein, Human, Recombinant (His)
Thymopoietin-Related Peptide Isoforms β/γ,Splenin,TMPO,T... |
Human | E. coli |
Thymopentin is a member of the LEM family. Thymopentin is expressed in many tissues, highly in the adult thymus and fetal liver. The N-terminal contains two structurally independent domains, LEM domain and LEM-like domain. The C-terminal domain forms a four-stranded coiled coil. Thymopentin may be involved in the structural organization of the nucleus and in the post-mitotic nuclear assembly. It is associated with T-cell development and function. Meantime, Thymopentin plays an important role, to... | |||
TMPY-06313 |
CD6 Protein, Human, Recombinant (His & Avi), Biotinylated
CD6 molecule,TP120 |
Human | HEK293 Cells |
CD6 Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with His and Avi tag. The predicted molecular weight is 43.83 kDa and the accession number is NP_006716.3. | |||
TMPY-04673 |
CD6 Protein, Human, Recombinant (hFc)
CD6 molecule,TP120 |
Human | HEK293 Cells |
CD6 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 67.3 kDa and the accession number is P30203-1. | |||
TMPY-02228 |
p53 Protein, Cynomolgus, Recombinant
tumor protein p53,p53,TP53 |
Cynomolgus | E. coli |
p53, also known as Tp53, is a DNA-binding protein which belongs to the p53 family. It contains transcription activation, DNA-binding, and oligomerization domains. p53 protein is expressed at low level in normal cells and at a high level in a variety of transformed cell lines, where it's believed to contribute to transformation and malignancy. p53 (TP53) is a transcription factor whose protein levels and post-translational modification state alter in response to cellular stress (such as DNA damag... | |||
TMPK-00697 |
CD6 Protein, Human, Recombinant (His)
CD6,TP120,T12 |
Human | HEK293 Cells |
The cell surface glycoprotein CD6 is expressed on leukocytes and mediates T cell trafficking across endothelial cell barriers. CD6 is a lymphocyte surface co-receptor physically associated with the T-cell receptor (TCR)/CD3 complex at the center of the immunological synapse. | |||
TMPY-06361 |
CD7 Protein, Human, Recombinant (hFc)
CD7 molecule,GP40,LEU-9,TP41,Tp40 |
Human | HEK293 Cells |
CD7 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 43.16 kDa and the accession number is NP_006128.1. | |||
TMPY-06688 |
CD7 Protein, Human, Recombinant (His & Avi), Biotinylated
LEU-9,CD7 molecule,GP40,Tp40,TP41 |
Human | HEK293 Cells |
CD7 Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with His and Avi tag. The predicted molecular weight is 19.69 kDa and the accession number is NP_006128.1. | |||
TMPK-00128 |
CD7 Protein, Human, Recombinant (His & Avi), PE-Labeled
LEU-9,TP41,CD7 molecule,Tp40,CD7,GP40 |
Human | HEK293 Cells |
CD7, also known as Leu-9, is an approximately 40 kDa glycosylated and palmitoylated transmembrane protein in the immunoglobulin superfamily.CD7 is expressed on T cells, NK cells , myeloid progenitor cells, and CD19 B progenitor cells. Among CD8 T cells, the CD7-bright population preferentially contains naïve and memory cells, while more weak expressors are primarily effector cells. CD7 Protein, Human, Recombinant (His & Avi), PE-Labeled is expressed in HEK293 mammalian cells with C-His-Avi tag. ... | |||
TMPK-00129 |
CD7 Protein, Human, Recombinant (His & Avi)
CD7,GP40,Tp40,CD7 molecule,LEU-9,TP41 |
Human | HEK293 Cells |
CD7, also known as Leu-9, is an approximately 40 kDa glycosylated and palmitoylated transmembrane protein in the immunoglobulin superfamily.CD7 is expressed on T cells, NK cells , myeloid progenitor cells, and CD19 B progenitor cells. Among CD8 T cells, the CD7-bright population preferentially contains naïve and memory cells, while more weak expressors are primarily effector cells. CD7 Protein, Human, Recombinant (His & Avi) is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicte... | |||
TMPK-00100 |
CD7 Protein (Primary Amine Labeling), Mouse, Recombinant (hFc), Biotinylated
TP41,CD7,CD7 molecule,Tp40,LEU-9,GP40 |
Mouse | HEK293 Cells |
CD7, also known as Leu-9, is an approximately 40 kDa glycosylated and palmitoylated transmembrane protein in the immunoglobulin superfamily.CD7 is expressed on T cells, NK cells , myeloid progenitor cells, and CD19 B progenitor cells. Among CD8 T cells, the CD7-bright population preferentially contains naïve and memory cells, while more weak expressors are primarily effector cells. CD7 Protein (Primary Amine Labeling), Mouse, Recombinant (hFc), Biotinylated is expressed in HEK293 mammalian cells... | |||
TMPK-00377 |
DPPIV/CD26 Protein, Cynomolgus/Rhesus macaque, Recombinant (His)
DPP4,DPPIV,ADCP2,CD26,ADABP,TP103,EC 3.4.14.5 |
Cynomolgus,Rhesus | HEK293 Cells |
CD26/dipeptidyl peptidase (DPP)IV is a membrane-bound protein found in many cell types of the body, and a soluble form is present in body fluids. There is longstanding evidence that various primary tumors and also metastases express DPPIV/CD26 to a variable extent. | |||
TMPJ-00102 |
CD28 Protein, Human/Cynomolgus, Recombinant (hFc & Avi), Biotinylated
CD28 molecule,CD28 antigen,CD28,TP44,T-cell-specifi... |
Human,Cynomolyus | HEK293 Cells |
CD28 Protein, Human/Cynomolgus, Recombinant (hFc & Avi), Biotinylated is expressed in HEK293 mammalian cells with C-Fc-Avi tag. The predicted molecular weight is 60-90 KDa and the accession number is P10747. | |||
TMPH-03642 |
TP_0608 Protein, Treponema pallidum, Recombinant (His & Myc)
Uncharacterized protein TP_0608 |
Treponema pallidum | E. coli |
N/A. TP_0608 Protein, Treponema pallidum, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 30.5 kDa and the accession number is O83617. | |||
TMPY-02483 |
ATP citrate lyase/ACLY Protein, Human, Recombinant (His)
ATPCL,ACL,ATP citrate lyase,CLATP |
Human | Baculovirus Insect Cells |
ATP citrate lyase, also known as Acly or Acl, is the primary enzyme responsible for the synthesis of cytosolic acetyl-CoA in many tissues. The enzyme is composed of two polymer chains which are polypeptides in human. ATP citrate lyase is responsible for catalyzing the conversion of citrate and CoA into acetyl-CoA and oxaloacetate, along with the hydrolysis of ATP. A definitive role for ATP citrate lyase in tumorigenesis has emerged from ATP citrate lyase RNAi and chemical inhibitor studies, show... | |||
TMPY-05033 |
5T4/TPBG Protein, Human, Recombinant (aa 60-345, His)
5T4AG,trophoblast glycoprotein,WAIF1,M6P1,5T4 |
Human | HEK293 Cells |
Trophoblast glycoprotein (TPBG), also known as 5T4, is the therapeutic target of several anticancer agents currently in clinical development, largely due to its high expression in tumors and low expression in normal adult tissues. 5T4/TPBG Protein, Human, Recombinant (aa 60-345, His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 33.1 kDa and the accession number is Q13641. | |||
TMPY-04125 |
PTP1B Protein, Human, Recombinant (His)
protein tyrosine phosphatase, non-receptor type 1,PTP |
Human | E. coli |
PTP1B, also known as PTPN1, belongs to the protein-tyrosine phosphatase (PTP) family. PTPs catalyze the hydrolysis of the phosphate monoesters specifically on tyrosine residues. Members of the PTP family share a highly conserved catalytic motif, which is essential for the catalytic activity. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. PTP1B contains 1 tyrosine-protein p... | |||
TMPK-00810 |
tPA Protein, Mouse, Recombinant (His)
PLAT,Reteplase,t-PA,tPA,Alteplase |
Mouse | HEK293 Cells |
Tissue plasminogen activator (tPA) is the predominant plasminogen activator present in the vascular and nervous systems.t tPA is not only neuroprotective for postnatal primary cortical neurons, but also that the predominant route for enhancing cell survival is via an mTORdependent mechanism. | |||
TMPJ-01204 |
TPSAB1 Protein, Human, Recombinant (His)
TPS1,tryptase alpha/beta 1,TPS2,tryptase α... |
Human | HEK293 Cells |
Tryptases are serine proteases with trypsin-like specificity. Together with chymases and Cathepsin G, tryptases are important players in mast cell mediation of inflammatory and allergic responses. Tryptase alpha/beta-1(TPSAB1), also known as mast cell protease 7 (MCPT7), it exhibits anticoagulant activity due to its ability to degrade fibrinogen in the presence of a diverse array of protease inhibitors in plasma. The two Isoform 1 and isoform 2 are expressed in lung, stomach, spleen, heart and s... | |||
TMPY-03548 |
PTPN12 Protein, Human, Recombinant
protein tyrosine phosphatase, non-receptor type 12,PTP |
Human | Baculovirus Insect Cells |
PTPN12 Protein, Human, Recombinant is expressed in Baculovirus insect cells. The predicted molecular weight is 41.8 kDa and the accession number is AAA36529.1. | |||
TMPY-03484 |
TCPTP Protein, Human, Recombinant
TCPTP,protein tyrosine phosphatase, non-receptor ty... |
Human | Baculovirus Insect Cells |
TCPTP Protein, Human, Recombinant is expressed in Baculovirus insect cells. The predicted molecular weight is 36.8 kDa and the accession number is P17706-1. | |||
TMPY-02929 |
ENTPD2 Protein, Human, Recombinant (aa 29-460, His)
ectonucleoside triphosphate diphosphohydrolase 2,NTP |
Human | Baculovirus Insect Cells |
NTPDase 2, also known as ENTPD2, belongs to the ecto-nucleoside triphosphate diphosphohydrolase family (E-NTPDase). Members of E-NTPDase family are nucleotidases able to hydrolyze 5′-nucleoside tri- and/or diphosphates; the main role of these enzymes is the termination of purinergic signaling. NTPDases are ubiquitous and were previously shown in other parasites including the trypanosomatides of genus Leishmania and in T. brucei. NTPase activity would act as a timer and is crucial to T. gondii in... | |||
TMPJ-00235 |
TPO Protein, Human, Recombinant (His)
Megakaryocyte growth and development factor,C-mpl ligand,Thr... |
Human | HEK293 Cells |
Thrombopoietin (TPO) is a glycoprotein hormone which belongs to the EPO/TPO family. It produced by the liver and kidney which regulates the production of platelets. TPO stimulates the production and differentiation of megakaryocytes, the bone marrow cells that bud off large numbers of platelets. Lineage-specific cytokine affects the proliferation and maturation of megakaryocytes from their committed progenitor cells. It acts at a late stage of megakaryocyte development. It may be the major physi... | |||
TMPY-02767 |
TPP1 Protein, Human, Recombinant (His)
tripeptidyl peptidase I,CLN2,TPP-1,SCAR7,GIG1,LPIC |
Human | Baculovirus Insect Cells |
TPP1 Protein, Human, Recombinant (His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 60.7 kDa and the accession number is AAH14863.1. | |||
TMPY-02639 |
ENTPD3 Protein, Human, Recombinant (His)
ectonucleoside triphosphate diphosphohydrolase 3,HB6,NTP... |
Human | Baculovirus Insect Cells |
ENTPD3 Protein, Human, Recombinant (His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 51 kDa and the accession number is O75355. | |||
TMPY-06810 |
SFTPB Protein, Human, Recombinant (His)
SFTP3,SMDP1,PSP-B,SFTB3,SP-B |
Human | CHO Cells |
Pulmonary surfactant-associated protein B, also known as SFTPB and SP-B, contains one saposin A-type domain and three saposin B-type domains. SP-B is produced primarily by alveolar type II cells (AEC2) but also by nonciliated respiratory epithelial cells lining distal portions of the respiratory tract. Its secretion promotes alveolar homeostasis, stabilizing lipid layers and lowering surface tension at the air-liquid interface in the peripheral air spaces. Alveolar SP-B influences surfactant for... | |||
TMPY-06191 |
5T4/TPBG Protein, Mouse, Recombinant (His)
trophoblast glycoprotein,WAIF1,5T4,AW495680 |
Mouse | HEK293 Cells |
Trophoblast glycoprotein (TPBG), also known as 5T4, is the therapeutic target of several anticancer agents currently in clinical development, largely due to its high expression in tumors and low expression in normal adult tissues. 5T4/TPBG Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 37.2 kDa and the accession number is Q9Z0L0. | |||
TMPY-03984 |
TPM1 Protein, Human, Recombinant (His)
TMSA,tropomyosin 1 (alpha),LVNC9,CMH3,HTM-alpha,CMD1Y,C15orf... |
Human | E. coli |
TPM1, also known as tropomyosin-1, is a member of the tropomyosin family. Members of this family are highly conserved, widely distributed actin-binding proteins involved in the contractile system of striated and smooth muscles and the cytoskeleton of non-muscle cells. highly conserved, widely distributed actin-binding proteins involved in the contractile system of striated and smooth muscles and the cytoskeleton of non-muscle cells. TPM1 is one type of alpha-helical chain that forms the predomin... | |||
TMPY-00487 |
PTPN9 Protein, Human, Recombinant (His & GST)
PTPMEG2,protein tyrosine phosphatase, non-receptor ... |
Human | Baculovirus Insect Cells |
Protein tyrosine phosphatase non-receptor type 9 (PTPN9), also named PTP-MEG2, is an important member of the protein tyrosine phosphatase family that is involved in variety of human diseases.PTPN9 plays an important role in erythropoiesis by disrupting an inhibitory complex of phosphorylated STAT3, GATA1 and ZBP-89, providing new cellular and molecular insights into the role of ptpn9a in developmental hematopoiesis. | |||
TMPY-03609 |
ATP5D Protein, Human, Recombinant (His)
ATP synthase, H+ transporting, mitochondrial F1 com... |
Human | E. coli |
ATP5D is a subunit of mitochondrial ATP synthase. Mitochondrial ATP synthase catalyzes ATP synthesis, utilizing an electrochemical gradient of protons across the inner membrane during oxidative phosphorylation. ATP synthase consists of two linked multi-subunit complexes: the soluble catalytic core, F1, and the membrane-spanning component, Fo, comprising the proton channel. The catalytic portion of mitochondrial ATP synthase consists of 5 different subunits (alpha, beta, gamma, delta, and epsilon... | |||
TMPY-02898 |
tPA Protein, Mouse, Recombinant (hFc)
plasminogen activator, tissue,AU020998,tPA,AW212668... |
Mouse | HEK293 Cells |
tPA Protein, Mouse, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 56.4 kDa and the accession number is P11214. | |||
TMPY-03788 |
ATP1B1 Protein, Human, Recombinant (His)
ATPase, Na+/K+ transporting, β 1 polypeptide,AT... |
Human | HEK293 Cells |
ATP1B1 belongs to the family of Na+/K+and H+/K+-ATPases beta chain proteins, and to the subfamily of Na+/K+ -ATPases. ATP1B1 is a subunit of Na+/K+-ATPase. Na+/K+-ATPase is an integral membrane protein responsible for establishing and maintaining the electrochemical gradients of Na and K ions across the plasma membrane. Na+/K+-ATPase is composed of two subunits, a large catalytic subunit (alpha) and a smaller glycoprotein subunit (beta). ATP1B1 regulates, through assembly of alpha/beta heterodim... | |||
TMPY-06214 |
5T4/TPBG Protein, Mouse, Recombinant (hFc)
trophoblast glycoprotein,AW495680,5T4,WAIF1 |
Mouse | HEK293 Cells |
Trophoblast glycoprotein (TPBG), also known as 5T4, is the therapeutic target of several anticancer agents currently in clinical development, largely due to its high expression in tumors and low expression in normal adult tissues. 5T4/TPBG Protein, Mouse, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 62.5 kDa and the accession number is Q9Z0L0. | |||
TMPY-02758 |
ENTPD5 Protein, Human, Recombinant (His)
NTPDase-5,ectonucleoside triphosphate diphosphohydr... |
Human | Baculovirus Insect Cells |
ENTPD5 Protein, Human, Recombinant (His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 47 kDa and the accession number is O75356. | |||
TMPY-02386 |
PTP4A2 Protein, Human, Recombinant (GST)
HNMT-S2,PRL-2,HNMT-S1,protein tyrosine phosphatase type IVA,... |
Human | E. coli |
PRL-2 (Protein-tyrosine phosphatase of regenerating liver 2), also known as PTP4A2 (Protein tyrosine phosphatase type IVA, member 2), is a member of PTP family and has an important function in controlling cell growth. PRL-2 phosphatases may be multifunctional enzymes with diverse roles in a variety of tissue and cell types. The phosphatase of regenerating liver (PRL) family, comprising PRL-1, PRL-2 and PRL-3, is a group of prenylated phosphatases that are candidate cancer biomarkers and therapeu... | |||
TMPY-04137 |
ATP6V1F Protein, Human, Recombinant (GST)
Vma7,ATPase, H+ transporting, lysosomal 14kDa, V1 s... |
Human | E. coli |
ATP6V1F encodes a component of vacuolar ATPase mediating acidification. The cDNA and the genomic sequences of ATP6V1F were cloned successfully for the first time from the Giant Panda (Ailuropoda melanoleuca) using reverse transcription polymerase chain reaction and touchdown-polymerase chain reaction, respectively. Topology prediction showed that there is one protein kinase C phosphorylation site, two Casein kinase II phosphorylation sites, and one N-myristoylation site in the ATP6V1F protein. U... | |||
TMPJ-00793 |
TPM3 Protein, Human, Recombinant
Tropomyosin α-3 Chain,γ-Tropomyosin,hTM5,Tropomyosin Alpha-3... |
Human | E. coli |
Tropomyosin Alpha-3 Chain (TPM3) is a member of the Tropomyosin family. TPM3 exists as a heterodimer consisting of an alpha and a beta chain. TPM3 plays a central role in association with the Troponin complex and in the calcium dependent regulation of vertebrate striated muscle contraction. Defects in TPM3 are the cause of thyroid papillary carcinoma. Mutations in the TPM3 gene cause autosomal dominant nemaline myopathy, and oncogenes formed by chromosomal translocations involving this locus are... | |||
TMPJ-00332 |
tPA Protein, Human, Recombinant (His)
TPA,T-PA,t-plasminogen activator,Tissue plasminogen... |
Human | HEK293 Cells |
Tissue-type plasminogen activator (PLAT) is a protein that secreted into extracellular space. PLAT contains five domains: EGF-like domain, fibronectin type-I domain, 2 kringle domains and peptidase S1 domain. It belongs to the peptidase S1 family. The main function of this protein is to convert plasminogen into biologically active plasmin. As a protease, PLAT plays a crucial role in regulating blood fibrinolysis, maintaining the homeostasis of extracellular matrix and in modulating the post-tra... | |||
TMPH-00968 |
ATP5C1 Protein, Human, Recombinant (His & Myc)
F-ATPase gamma subunit,ATP5C1,ATP... |
Human | E. coli |
ATP5C1 Protein, Human, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 37.6 kDa and the accession number is P36542. | |||
TMPH-00965 |
ATP5F1A Protein, Human, Recombinant (His)
ATP5F1A,ATP5A,ATP synthase subuni... |
Human | E. coli |
ATP5F1A Protein, Human, Recombinant (His) is expressed in E. coli. | |||
TMPH-00581 |
ATP-dependent Clp protease adapter protein ClpS Protein, E. coli, Recombinant (His)
yljA,ATP-dependent Clp protease adapter protein Clp... |
E. coli | E. coli |
Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation. ATP-dependent Clp protease adapter protein ClpS Protein, E. coli, Recombinant (His) is expressed in E. coli expression system with His tag. The predicted molecular weight is 16.2?kDa and the accession number is P0A8Q6. | |||
TMPH-03249 |
ATP5F1B Protein, Rat, Recombinant (His & Myc)
ATPMB,ATPSB,ATP synthase subunit ... |
Rat | E. coli |
ATP5F1B Protein, Rat, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 59.2 kDa and the accession number is P10719. | |||
TMPH-03085 |
LTP2 Protein, Parietaria judaica, Recombinant (His & SUMO)
Allergen Par j II,Probable non-specific lipid-transfer prote... |
Parietaria judaica | E. coli |
Plant non-specific lipid-transfer proteins transfer phospholipids as well as galactolipids across membranes. May play a role in wax or cutin deposition in the cell walls of expanding epidermal cells and certain secretory tissues. LTP2 Protein, Parietaria judaica, Recombinant (His & SUMO) is expressed in E. coli expression system with N-6xHis-SUMO tag. The predicted molecular weight is 27.3 kDa and the accession number is P55958. | |||
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Cat. No. | Product Name | Target | Signaling Pathways |
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T31108 |
CTP-347
CTP347,CTP 347 |
||
CTP-347, a deuterated version of paroxetine, is potentially the best non-hormonal drug in its class for the treatment of hot flashes. | |||
T27097 |
CTP518
CTP 518,Deuterated Atazanivir-D3-1,CTP-518 |
||
CTP518, a deuterated Atazanivir derivative, is a HIV protease inhibitor. | |||
T31109 |
CTP-499
|
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CTP499, a selective PDE inhibitor, and the deuterium-containing agent is an HDX analogue and a metabolite of hexantheobromine that slows the progression of type 2 diabetic nephropathy in patients with macroalbuminuria. |