首页工具

登录

搜索结果

Search Results for " tead4 "

Targets Recommended: YAP

3

抑制剂 & 化合物

5

重组蛋白

如果没找到您满意的产品或者您对产品有其他要求，可以联系我们专业顾问为您提供针对性的合理建议。 QQ咨询网站留言咨询

Cat. No.	Product Name	Target	Signaling Pathways
T8421	TED-347	YAP	Stem Cells
	TED-347 是不可逆的、共价的 YAP-TEAD 蛋白质-蛋白质相互作用变构抑制剂，对 TEAD4•Yap1 蛋白质-蛋白质相互作用的 EC50为 5.9 μM。它与 TEAD4 中央口袋内的 Cys-367 特异性共价结合(Ki:10.3 μM)。它可以抑制 TEAD 的转录活性，并且具有抗肿瘤作用。
T9032	MGH-CP1	Others	Others
	MGH-CP1 是 TEAD2 (IC50:710 nM) 及 TEAD4 (IC50:672 nM) 自棕榈酰化抑制剂，口服有活性，可降低细胞内源性或异位表达的 TEAD 蛋白棕榈酰化水平。MGH-CP1 与 Lats1/2 缺失，是 Myc 的表达受到抑制，阻碍上皮细胞过度增殖，诱导细胞凋亡。
T83951	TM2 TEAD inhibitor	Others	Others
	TM2 TEAD抑制剂是一种有效并且可逆的TEA领域转录因子抑制剂(IC50为TEAD4自动棕榈酰化和TEAD2棕榈酰化分别为38 nM和156 nM)。它抑制TEAD-YAP的结合和转录活性。TM2 TEAD抑制剂在YAP依赖型癌症细胞中，无论是单独使用还是与MEK抑制剂联合使用，都显示出强大的抗增殖效果。同时抑制体外YAP依赖的肝脏类器官生长。

化合物

Cat.No: T8421

Target: YAP

Cat.No: T9032

Target: Others

TM2 TEAD inhibitor

Cat.No: T83951

Target: Others

Species：

Expression System：

Tag：

Cat. No.	Product Name	Species	Expression System
TMPH-02223	TEAD4 Protein, Human, Recombinant (His) Transcription factor 13-like 1,Transcription factor RTEF-1,T...	Human	E. coli
	TEAD4 Protein, Human, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 44.7 kDa and the accession number is Q15561.
TMPH-02943	TEAD4 Protein, Mouse, Recombinant TEA domain family member 4,TEF-1-related factor 1,<...	Mouse	E. coli
	TEAD4 Protein, Mouse, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 25.7 kDa and the accession number is Q62296.
TMPH-02224	TEAD4 Protein, Human, Recombinant (His & Myc) Transcription factor 13-like 1,TEA domain family member ...	Human	Baculovirus Insect Cells
	TEAD4 Protein, Human, Recombinant (His & Myc) is expressed in Baculovirus insect cells with N-10xHis and C-Myc tag. The predicted molecular weight is 44.5 kDa and the accession number is Q15561.
TMPH-02942	TEAD4 Protein, Mouse, Recombinant (His & Myc) TEF-1-related factor FR-19,TEF-1-related factor 1,TEA domain...	Mouse	E. coli
	TEAD4 Protein, Mouse, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 33.0 kDa and the accession number is Q62296.
TMPH-03764	YAP1 Protein, Human, Recombinant (His) YAP1-2gamma,YAP2L,YAP65	Human	P. pastoris (Yeast)
	Transcriptional regulator which can act both as a coactivator and a corepressor and is the critical downstream regulatory target in the Hippo signaling pathway that plays a pivotal role in organ size control and tumor suppression by restricting proliferation and promoting apoptosis. The core of this pathway is composed of a kinase cascade wherein STK3/MST2 and STK4/MST1, in complex with its regulatory protein SAV1, phosphorylates and activates LATS1/2 in complex with its regulatory protein MOB1,...

重组蛋白

TEAD4 Protein, Human, Recombinant (His)

Cat.No: TMPH-02223

Species: Human

Expression System: E. coli

TEAD4 Protein, Mouse, Recombinant

Cat.No: TMPH-02943

Species: Mouse

Expression System: E. coli

TEAD4 Protein, Human, Recombinant (His & Myc)

Cat.No: TMPH-02224

Species: Human

Expression System: Baculovirus Insect Cells

TEAD4 Protein, Mouse, Recombinant (His & Myc)

Cat.No: TMPH-02942

Species: Mouse

Expression System: E. coli

YAP1 Protein, Human, Recombinant (His)

Cat.No: TMPH-03764

Species: Human

Expression System: P. pastoris (Yeast)

我们的所有产品和服务仅用于科学研究，不能被用于人体，我们也不向个人提供产品和服务。

Copyright © 2015-2024 TargetMol Chemicals Inc. All rights reserved. 沪ICP备20019793号-4

沪公网安备 31010602006700号

沪公网安备 31010602006700号

TargetMol Loading

联系我们

电话：

400-820-0310

邮箱：

service@tsbiochem.com

QQ：

2881945090（终端用户）

2885109491（经销商）

经销：

终端：

地址：

上海市静安区江场三路238号8楼