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Targets Recommended: Antibacterial Antibiotic

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Cat. No. Product Name Target Signaling Pathways
T1224 Cefuroxime sodium

Anaptivan,头孢呋辛钠,Cefuroxime sodium salt,Biociclin

 Antibacterial; Antibiotic Microbiology/Virology
Cefuroxime sodium (Cefuroxime sodium salt) 是一种具有口服活性的头孢菌素抗生素，增加了对 β-内酰胺酶的稳定性。
T22279 BRD0539

CRISPR/Cas9 DNA Damage/DNA Repair
BRD0539 是一种具有细胞渗透性的 spCas9 抑制剂，可阻断 spCas9 与 DNA 的结合，抑制化脓性链球菌 Cas9 (SpCas9)。
T13406L Zabofloxacin hydrochloride

DW-224a

 Raf MAPK
Zabofloxacin hydrochloride is a potent and seletive bacterial type II and IV topoisomerases inhibitor, has excellent activity against gram-positive pathogens including Steptococcus aureus, Streptococcus pyogenes and S.pneumonia.
T13406 Zabofloxacin

DW-224a Free base

 Others Others
Zabofloxacin is a potent and seletive bacterial type II and IV topoisomerases inhibitor, and has excellent activity against gram-positive pathogens including Steptococcus aureus, Streptococcus pyogenes and S.pneumonia.
T30311 Bederocin

REP 8839,REP-8839,REP8839

 Antibacterial Microbiology/Virology
Bederocin (REP8839) 是一种新型的甲硫酰基tRNA 合成酶(METS)抑制剂，对临床分离的金黄色葡萄球菌、化脓性链球菌和其他临床重要的革兰氏阳性细菌具有有效的抗菌活性。
T76467 Acetyl-Adhesin (1025-1044) amide

Acetyl-Adhesin (1025-1044) amide，为变形链球菌细胞表面粘连蛋白20肽段，充当抗菌肽，特异性阻止粘连素同唾液受体结合，避免变形链球菌再定植。

化合物

Cefuroxime sodium
Cat.No: T1224
Synonym: Anaptivan,头孢呋辛钠,Cefuroxime sodium salt,Biociclin
Target: Antibacterial, Antibiotic
BRD0539
Cat.No: T22279
Synonym:
Target: CRISPR/Cas9
Zabofloxacin hydrochloride
Cat.No: T13406L
Synonym: DW-224a
Target: Raf
Zabofloxacin
Cat.No: T13406
Synonym: DW-224a Free base
Target: Others
Bederocin
Cat.No: T30311
Synonym: REP 8839,REP-8839,REP8839
Target: Antibacterial
Acetyl-Adhesin (1025-1044) amide
Cat.No: T76467
Synonym:
Target:
Species：
Streptococcus pyogenes (9)
Expression System：
E. coli (6)
Baculovirus Insect Cells (2)
P. pastoris (Yeast) (1)
Tag：
N-10xHis, C-Myc (3)
N-6xHis-SUMO (3)
C-His (1)
His, GST (1)
N-His (1)
Cat. No. Product Name Species Expression System
TMPY-05346 CRISPR-Cas9 Protein, Streptococcus pyogenes, Recombinant (His)

SpyCas9

 Streptococcus pyogenes Baculovirus Insect Cells
CRISPR-Cas9 Protein, Streptococcus pyogenes, Recombinant (His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 163 kDa and the accession number is Q99ZW2.
TMPY-06023 IdeS Protein, Streptococcus pyogenes, Recombinant (His)

Streptococcus pyogenes E. coli
IdeS (IgG-degrading enzyme of Streptococcus pyogenes) is a secreted cysteine endopeptidase from the human pathogen S. pyogenes with an extraordinarily high degree of substrate specificity, catalyzing a single proteolytic cleavage at the lower hinge of human IgG. This proteolytic degradation promotes inhibition of opsonophagocytosis and interferes with the killing of group A Streptococcus. IdeS Protein, Streptococcus pyogenes, Recombinant (His) is expressed in E. coli expression system with His t...
TMPY-06179 IdeS Protein, Streptococcus pyogenes, Recombinant (His & GST)

Streptococcus pyogenes E. coli
IdeS (IgG-degrading enzyme of Streptococcus pyogenes) is a secreted cysteine endopeptidase from the human pathogen S. pyogenes with an extraordinarily high degree of substrate specificity, catalyzing a single proteolytic cleavage at the lower hinge of human IgG. This proteolytic degradation promotes inhibition of opsonophagocytosis and interferes with the killing of group A Streptococcus. IdeS Protein, Streptococcus pyogenes, Recombinant (His & GST) is expressed in E. coli expression system with...
TMPH-03595 APT Protein, S. pyogenes serotype M1, Recombinant (His & Myc)

Adenine phosphoribosyltransferase,apt,APRT

 Streptococcus pyogenes P. pastoris (Yeast)
Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. APT Protein, S. pyogenes serotype M1, Recombinant (His & Myc) is expressed in yeast with N-10xHis and C-Myc tag. The predicted molecular weight is 22.7 kDa and the accession number is P63546.
TMPH-03599 Streptopain Protein, S. pyogenes, Recombinant (His & SUMO)

Group A streptococcal cysteine protease,SPE B,Streptococ...

 Streptococcus pyogenes E. coli
Important streptococcal virulence factor which cleaves human fibronectin and degrades vitronectin. Also cleaves human IL1B precursor to form biologically active IL1B. Can induce apoptosis in human monocytes and epithelial cells in vitro, and reduces phagocytic activity in monocytic cells. Thus, may play a role in bacterial colonization, invasion, and inhibition of wound healing. Streptopain Protein, S. pyogenes, Recombinant (His & SUMO) is expressed in E. coli expression system with N-6xHis-SUMO...
TMPH-03598 Streptopain Protein, S. pyogenes serotype M28, Recombinant (His & SUMO)

SPE B,Streptococcus peptidase A,Streptopain,Strepto...

 Streptococcus pyogenes E. coli
Important streptococcal virulence factor which cleaves human fibronectin and degrades vitronectin. Also cleaves human IL1B precursor to form biologically active IL1B. Can induce apoptosis in human monocytes and epithelial cells in vitro, and reduces phagocytic activity in monocytic cells. Thus, may play a role in bacterial colonization, invasion, and inhibition of wound healing. Streptopain Protein, S. pyogenes serotype M28, Recombinant (His & SUMO) is expressed in E. coli expression system with...
TMPH-03594 Exotoxin type A Protein, S. pyogenes, Recombinant (His & SUMO)

SPE A,Scarlet fever toxin,Exotoxin type A,speA,Erythrogenic ...

 Streptococcus pyogenes E. coli
Causative agent of the symptoms associated with scarlet fever, have been associated with streptococcal toxic shock-like disease and may play a role in the early events of rheumatic fever. Exotoxin type A Protein, S. pyogenes, Recombinant (His & SUMO) is expressed in E. coli expression system with N-6xHis-SUMO tag. The predicted molecular weight is 38.6 kDa and the accession number is P0DJY7.
TMPH-03596 Holo-ACP synthase Protein, S. pyogenes serotype M28, Recombinant (His & Myc)

acpS,4'-phosphopantetheinyl transferase AcpS,Holo-[acyl-carr...

 Streptococcus pyogenes Baculovirus Insect Cells
Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein. Holo-ACP synthase Protein, S. pyogenes serotype M28, Recombinant (His & Myc) is expressed in Baculovirus insect cells with N-10xHis and C-Myc tag. The predicted molecular weight is 17.1 kDa and the accession number is Q48RM7.
TMPH-03597 Holo-ACP synthase Protein, S. pyogenes serotype M28, Recombinant (E. coli, His & Myc)

4'-phosphopantetheinyl transferase AcpS,Holo-[acyl-carrier-p...

 Streptococcus pyogenes E. coli
Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein. Holo-ACP synthase Protein, S. pyogenes serotype M28, Recombinant (E. coli, His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 18.3 kDa and the accession number is Q48RM7.

重组蛋白

CRISPR-Cas9 Protein, Streptococcus pyogenes, Recombinant (His)
Cat.No: TMPY-05346
Species: Streptococcus pyogenes
Expression System: Baculovirus Insect Cells
IdeS Protein, Streptococcus pyogenes, Recombinant (His)
Cat.No: TMPY-06023
Species: Streptococcus pyogenes
Expression System: E. coli
IdeS Protein, Streptococcus pyogenes, Recombinant (His & GST)
Cat.No: TMPY-06179
Species: Streptococcus pyogenes
Expression System: E. coli
APT Protein, S. pyogenes serotype M1, Recombinant (His & Myc)
Cat.No: TMPH-03595
Species: Streptococcus pyogenes
Expression System: P. pastoris (Yeast)
Streptopain Protein, S. pyogenes, Recombinant (His & SUMO)
Cat.No: TMPH-03599
Species: Streptococcus pyogenes
Expression System: E. coli
Streptopain Protein, S. pyogenes serotype M28, Recombinant (His & SUMO)
Cat.No: TMPH-03598
Species: Streptococcus pyogenes
Expression System: E. coli
Exotoxin type A Protein, S. pyogenes, Recombinant (His & SUMO)
Cat.No: TMPH-03594
Species: Streptococcus pyogenes
Expression System: E. coli
Holo-ACP synthase Protein, S. pyogenes serotype M28, Recombinant (His & Myc)
Cat.No: TMPH-03596
Species: Streptococcus pyogenes
Expression System: Baculovirus Insect Cells
Holo-ACP synthase Protein, S. pyogenes serotype M28, Recombinant (E. coli, His & Myc)
Cat.No: TMPH-03597
Species: Streptococcus pyogenes
Expression System: E. coli
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