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Search Results for " streptococcus "

Targets Recommended: Antibacterial Antibiotic

49

抑制剂 & 化合物

15

天然产物

20

重组蛋白

2

同位素标记化合物

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Cat. No.	Product Name	Target	Signaling Pathways
T6231	Tebipenem Pivoxil ME1211,Orapenem,替比培南匹酯	Antibacterial; Antibiotic	Microbiology/Virology
	Tebipenem Pivoxil (Orapenem) 是一种碳青霉烯类新型口服抗生素。
T1224	Cefuroxime sodium Anaptivan,头孢呋辛钠,Cefuroxime sodium salt,Biociclin	Antibacterial; Antibiotic	Microbiology/Virology
	Cefuroxime sodium (Cefuroxime sodium salt) 是一种具有口服活性的头孢菌素抗生素，增加了对 β-内酰胺酶的稳定性。
T2691	Oritavancin diphosphate 奥利万星二磷酸盐,LY333328 diphosphate	Others; Antibacterial; Antibiotic	Microbiology/Virology; Others
	Oritavancin diphosphate (LY333328 diphosphate) 是一种新型半合成的糖肽抗生素, 可研究革兰氏阳性菌感染。
T77521	HA5	Antibacterial	Microbiology/Virology
	HA5 具有抗菌活性，抑制变形链球菌 (Streptococcus mutans) 生物膜形成，IC50 值为 6.42 μM。HA5 抑制变形链球菌葡聚糖的产生和 eDNA 水平，但对链球菌的生长无抑制作用。
T22279	BRD0539	CRISPR/Cas9	DNA Damage/DNA Repair
	BRD0539 是一种具有细胞渗透性的 spCas9 抑制剂，可阻断 spCas9 与 DNA 的结合，抑制化脓性链球菌 Cas9 (SpCas9)。
T77551	6'-hydroxydihydrocinchonidine	Antibiotic; Drug Metabolite	Metabolism; Microbiology/Virology
	6'-hydroxydihydrocinchonidine 是奎宁的代谢产物,具有抗菌和抗肿瘤活性，对布氏锥虫和肺炎链球菌有抑制作用。
T0331L	Moxifloxacin Avelox,Moxeza,莫西沙星	Others; Antibacterial; Antibiotic	Microbiology/Virology; Others
	Moxifloxacin (Avelox) 是一种8-甲氧基喹诺酮类口服有效抗菌药物，用于急性细菌性鼻窦炎，慢性支气管炎的急性细菌性加重和感染性肺炎的研究。
T4063	Delafloxacin ABT492,WQ-3034,德拉沙星,RX-3341	Antibacterial; Antibiotic	Microbiology/Virology
	Delafloxacin (WQ-3034) 是一种广谱氟喹诺酮类抗生素，抑制耐药性的金黄色葡萄球菌，肺炎链球菌和肺炎克雷伯菌。
T38137	3,5-Dimethylbenzaldehyde	Endogenous Metabolite; Antifungal	Metabolism; Microbiology/Virology
	3,5-Dimethylbenzaldehyde 具有广谱的抗菌活性，对枯草芽孢杆菌、白假丝酵母菌、大肠杆菌、铜绿假单胞菌、金黄色葡萄杆菌和肺炎链球菌具有抑制作用。
T14386	AZD9567 Mizacorat	Glucocorticoid Receptor	Endocrinology/Hormones
	AZD9567 是一种强效且具有口服活性和选择性的非类固醇糖皮质激素受体调节剂（SGRM），其 IC50 值为 3.8 nM。它在链球菌细胞壁（SCW）再活化关节炎症模型中显示出卓越的疗效。
T11265	Faropenem daloxate 法罗培南酯,Faropenem medoxil	Antibacterial; Antibiotic	Microbiology/Virology
	Faropenem daloxate (Faropenem medoxil) 是β-内酰胺类口服抗生素。
T7872	Monolaurin	Others	Others
	Monolaurin 是椰子油中的一种表面活性剂和乳化剂。它抑制葡萄球菌、链球菌、加德纳菌、念珠菌和嗜血杆菌的生长，并减少促炎细胞因子的产生。
T77633	G43 G 43,G-43	Antibacterial; Transferase	Metabolism; Microbiology/Virology
	G43 是一种有效的选择性 glucosyltransferase 抑制剂，对 GtfB 和 GtfC 具有抑制作用，Kd 值分别为3.7 μM和46.9 nM。G43 在体内外具有抗变形链球菌 (S. mutans)活性，可用于研究龋齿。
T2331	Solithromycin 索利霉素,OP-1068,CEM-101	Antibacterial; Antibiotic	Microbiology/Virology
	Solithromycin (OP-1068) 是口服可生物利用的抗菌剂，抑制肺炎链球菌、葡萄球菌、金黄色葡萄球菌和流感嗜血杆菌的细胞活力、蛋白质合成和生长速率， IC50 值分别为 7.5 ng/mL、40 ng/mL 和 125 ng/mL。它可与核糖体的大 50S 亚基结合抑制蛋白质生物合成。
T1492	Gemifloxacin mesylate LB-20304a,甲磺酸吉米沙星,SB-265805S,Gemifloxacin mesylate	DNA gyrase; Topoisomerase; Antibacterial	DNA Damage/DNA Repair; Microbiology/Virology
	Gemifloxacin mesylate (Gemifloxacin mesylate) 是一种喹诺酮类口服广谱抗菌剂，可研究轻中度肺炎和慢性支气管炎的急性细菌性发作。
T0391	Linezolid PNU-100766,雷奈佐利	MAO; Antibacterial; Antibiotic	Metabolism; Microbiology/Virology; Neuroscience
	Linezolid (PNU-100766) 是恶唑烷酮类合成抗生素，抑制细菌蛋白质合成的起始阶段，具有抗感染作用。
T40417	Ethylhydrocupreine hydrochloride Optochin hydrochloride,乙氢去甲奎宁盐酸盐；奥普托欣盐酸盐	Antibacterial; Parasite	Microbiology/Virology
	Ethylhydrocupreine hydrochloride (Optochin hydrochloride) 是奎宁的一种衍生物，具有抗菌作用，可抑制肺炎链球菌的活性。Ethylhydrocupreine hydrochloride 具有抗疟活性，对 Plasmodium falciparum 的IC50为 25.75 nM。Ethylhydrocupreine hydrochloride 是Gallus gallus2 受体 (ggTas2r1，ggTas2r2和ggTas2r7) 激动剂。
T28209	NSC65847	Others	Others
	NSC65847 is a novel dual inhibitor of viral and Streptococcus pneumoniae neuraminidase.
T34318	Rhizopterin Formylpteroic acid	Others	Others
	Rhizopterin is a growth factor for Streptococcus lactis R.
T32990	LY 164846 LY164846,LY-164846,7-Bgmcc	Others	Others
	LY 164846 is a novel oral cephalosporin that is effective against Staphylococcus, Streptococcus, Haemophilus influenzae, Catabella and Neisseria.
T70835	（4R，9S)-AG 205	Others	Others
	AG-205 is a potent inhibitor of FabK, the enoyl-ACP reductase in Streptococcus pneumoniae.
T38559	Competence-Stimulating Peptide-2 (CSP-2)
	Competence-Stimulating Peptide-2 (CSP-2) is a quorum sensing signal peptide synthesized by Streptococcus pneumoniae. ComD2, a compatible receptor of CSP-2, exhibits an EC 50 value of 50.7 nM.
T5189L	Omadacycline mesylate PTK 0796,PTK-0796,PTK0796	Others	Others
	Omadacycline is an aminomethylcycline antibiotic. Omadacycline demonstrated net cidal activity in relation to the initial burden against four strains of Streptococcus pneumoniae.
T25767	Lysobactin Katanosin A, 7-L-isoleucine-,Katanosin B
	Lysobactin, also known as katanosin B, is an effective antibiotic with in vivo efficacy against Staphylococcus aureus and Streptococcus pneumoniae. It was previously shown to inhibit peptidoglycan (PG) biosynthesis.
T13406L	Zabofloxacin hydrochloride DW-224a	Raf	MAPK
	Zabofloxacin hydrochloride is a potent and seletive bacterial type II and IV topoisomerases inhibitor, has excellent activity against gram-positive pathogens including Steptococcus aureus, Streptococcus pyogenes and S.pneumonia.
T70878	P516-0475	Others	Others
	P516-0475 is a novel chemical inducer of Streptococcus quorum sensing acts by inhibiting the pheromone-degrading endopeptidase PepO. This compound induces quorum sensing by stabilizing SHP pheromones in culture.
T13406	Zabofloxacin DW-224a Free base	Others	Others
	Zabofloxacin is a potent and seletive bacterial type II and IV topoisomerases inhibitor, and has excellent activity against gram-positive pathogens including Steptococcus aureus, Streptococcus pyogenes and S.pneumonia.
T24990	8-Deazafolic acid NSC-173522,NSC173522,NSC 173522	Others	Others
	8-Deazafolic acid is a potent folate-dependent bacteria inhibitor, Streptococcus faecium (ATCC 8043) and Lactobacillus casei (ATCC 7469), and to have activity against lymphoid leukemia L1210 in mice.
TP1358	Peptide M
	Peptide M is a synthetic Peptide, 50 aa, derived from streptococcus M protein, containing an additional c-terminal cysteine residue.
T76467	Acetyl-Adhesin (1025-1044) amide
	Acetyl-Adhesin (1025-1044) amide，为变形链球菌细胞表面粘连蛋白20肽段，充当抗菌肽，特异性阻止粘连素同唾液受体结合，避免变形链球菌再定植。
T38608	Brilacidin tetrahydrochloride PMX 30063 tetrahydrochloride	Others	Others
	Brilacidin tetrahydrochloride (PMX 30063 tetrahydrochloride) is a defensin mimetic antibiotic compound, exhibiting potent anti-infective antimicrobial activity against a range of bacteria. It demonstrates MIC90 values of 1 μg/mL and 8 μg/mL against the Gram-positive bacteria Streptococcus pneumoniae and Streptococcus viridans, respectively. Additionally, it has a MIC90 value of 8 μg/mL for the Gram-negative bacteria Haemophilus influenzae and a MIC90 value of 4 μg/mL for Pseudomonas aeruginosa.
T80317	Combi-2
	Combi-2为针对S.aureus、S.sanguis及E.coli具有抗菌活性的肽类化合物。
T38586	Grepafloxacin dl-Grepafloxacin,OPC-17116	Others	Others
	Grepafloxacin (OPC-17116) is a fluoroquinolone antibiotic that is administered orally. It possesses strong efficacy against community-acquired respiratory pathogens, notably Streptococcus pneumonia. Grepafloxacin exhibits excellent tissue penetration and demonstrates a promising pharmacodynamic profile.
T30481	BK 218 BK218,BK-218	Others	Others
	BK 218 is a novel cephalosporin, which is active against streptococcus pneumoniae, Haemophilus influenza, and Moraxella catarrase, but has a higher MIC against penicillin-resistant strains. Bk-218 has dual administration routes and the activity spectrum m
T80280	TLN-58
	TLN-58是一种抗菌肽，对S. aureus、S. epidermidis和group A Streptococcus显示出抗菌活性。此外，TLN-58能够在正常人角质形成细胞及NCL-SG3细胞中诱导炎症细胞因子mRNA的上调。
T30311	Bederocin REP 8839,REP-8839,REP8839	Antibacterial	Microbiology/Virology
	Bederocin (REP8839) 是一种新型的甲硫酰基tRNA 合成酶(METS)抑制剂，对临床分离的金黄色葡萄球菌、化脓性链球菌和其他临床重要的革兰氏阳性细菌具有有效的抗菌活性。
T28311	PD 116152 PD116,152,PD 116,152,PD116152,PD-116,152,PD-116152	Others	Others
	PD 116152 is a highly substituted phenazine with antitumor activity isolated from the culture broth of a Streptomyces sp. The antitumor activity versus murine P388 leukemia is T/C 149. PD 116152 is selectively active versus the bacterium Streptococcus pne
T81071	Suicin 65	ADC Cytotoxin	Antibody-drug Conjugate/ADC Related
	Suicin 65, 一种B型抗生素，源自链球菌，对所有猪链球菌展现出活性。
T81737	MurF-IN-1	Others	Others
	MurF-IN-1 (Compound 7)，一种MurF抑制剂，展现了针对S. pneumoniae MurF的显著抑制活性，其pIC50值为5.19。
T80252	BMAP-18
	BMAP-18为一抗菌肽，是Cathelicidin肽家族中的成员，为BMAP-27的截短版，具备针对Staphylococcus aureus、Streptococcus uberis和Escherichia coli的快速杀菌作用。相比其亲本BMAP-27，BMAP-18展现出优越的细胞选择性，降低了对人红细胞和中性粒细胞的溶血作用，同时保留其抗菌能力。
T37433	Erythromycin lactobionate	Others	Others
	Erythromycin is a macrolide antibiotic that inhibits bacterial protein synthesis by targeting the 50S ribosomal subunit, blocking the progression of nascent polypeptide chains.[1] It is effective against a host of bacterial genera, including Streptococcus, Staphylococcus, and Haemophilus (MIC90s range from 0.015-2.0 mg/l).[2] Erythromycin is known to potently inhibit the cytochrome P450 isoform CYP3A4, which can affect the metabolism of numerous clinically relevant medications.[3],[4] Erythromyc...
T28314	PD 117588 PD117588,PD-117588	Others	Others
	PD 117588 is a quinolone against bacterial isolates from cancer patients. PD 117558 has a broad antimicrobial spectrum with excellent activity against all Gram-positive isolates (including methicillin-resistant Staphylococcus aureus, coagulase-negative st
T84965	C82	Others	Others
	C82 acts as an inhibitor of Mycobacterium tuberculosis (Mtb) cyclic dinucleotide phosphodiesterase (CdnP), with an IC50 value of 17.5 µM. This particular enzyme is responsible for breaking down cyclic di-AMP (c-di-AMP) into adenosine 5'-monophosphate (AMP). Notably, C82 demonstrates selectivity for Mtb CdnP over other bacterial cyclic dinucleotide phosphodiesterases (CDN PDEs) such as Yybt, RocR, and Group B Streptococcus (GBS) CdnP, as well as the mammalian CDN PDE ENPP1, and the viral CDN PDE ...
T37432	Erythromycin A N-oxide	Others	Others
	Erythromycin A N-oxide is a potential impurity found in commercial preparations of erythromycin. Erythromycin is a macrolide antibiotic that inhibits bacterial protein synthesis by targeting the 50S ribosomal subunit, blocking the progression of nascent polypeptide chains. It is effective against a host of bacterial genera, including Streptococcus, Staphylococcus, and Haemophilus (MIC90s = 0.015-2.0 mg/l). Erythromycin is known to potently inhibit the cytochrome P450 isoform CYP3A4, which can af...
T71266	Omadacycline HCl	Others	Others
	Omadacycline, also known as PTK 0796 and Amadacyclin, is a novel first-in-class aminomethylcycline with potent activity against important skin and pneumonia pathogens, including community-acquired methicillin-resistant Staphylococcus aureus (MRSA), β-hemolytic streptococci, penicillin-resistant Streptococcus pneumoniae, Haemophilus influenzae, and Legionella. Omadacycline is active against strains expressing the two main forms of tetracycline resistance (efflux and ribosomal protection). The pri...
T35731	Deethylindanomycin	Others	Others
	Deethylindanomycin is a polyether antibiotic that has been found in S. setonii. It is active against a variety of Gram-positive bacteria, including various strains of S. aureus and Streptococcus, as well as one strain of S. pneumoniae (MICs = 4, 4, and 2 μg/ml, respectively). It is also active against coccidia in vitro, inhibiting E. tenella development, but is inactive against E. tenella infection in chicks when administered at a dose of 200 μg/g in the diet. Deethylindanomycin acts as an ionop...
T74591	Ceftaroline fosamil (hydrate)(acetate)	Others	Others
	Ceftaroline fosamil hydrate acetate 是一种高效的头孢菌素类抗生素(antibiotic)，对多种病原体有广谱活性，特别是针对革兰氏阳性病原体，如耐甲氧西林金黄色葡萄球菌(MRSA)和耐多药肺炎链球菌，以及常见的革兰氏阴性微生物。此外，Ceftaroline fosamil hydrate acetate 在治疗复杂皮肤及皮肤结构感染(cSSSIs)和社区获得性肺炎(CABP)方面表现出显著的抗感染活性。
T61489	VEGFR-2/DHFR-IN-1	Others	Others
	VEGFR-2/DHFR-IN-1 (compound 8b) 是 VEGFR-2和DHFR 的抑制剂，其IC50值分别为 0.384 和 7.881 μM。VEGFR-2/DHFR-IN-1 对大肠埃希菌，粪链球菌，肠沙门氏菌，金黄色酿脓葡萄球菌，MSSA 和MRSA 显示了良好的抗菌活性，MIC 值分别为 16，16，16，8 和 16 μg/mL。VEGFR-2/DHFR-IN-1 对 C26，HepG2 和 CF7 癌细胞系具有良好的细胞毒性，IC50值为 2.97-7.12 μM。VEGFR-2/DHFR-IN-1 可用于癌症的研究。
T36409	Roccellic Acid	Others	Others
	Roccellic acid is a lichen secondary metabolite that has been found in R. montagnei and has antibacterial and anticancer activities.1,2 It is active against the bacteria S. gordonii and P. gingivalis (MIC = 46.9 μg/ml for both).1 Roccellic acid (100 μg/ml) inhibits proliferation of MDA-MB-231, MCF-7, and DLD-1 cancer cells by 65.3, 75.8, and 87.9%, respectively.2 \|1. Sweidan, A., Chollet-Krugler, M., Sauvager, A., et al. Antibacterial activities of natural lichen compounds against Streptococcus ...

化合物

Tebipenem Pivoxil

Cat.No: T6231

Synonym: ME1211,Orapenem,替比培南匹酯

Target: Antibacterial, Antibiotic

Cefuroxime sodium

Cat.No: T1224

Synonym: Anaptivan,头孢呋辛钠,Cefuroxime sodium salt,Biociclin

Target: Antibacterial, Antibiotic

Oritavancin diphosphate

Cat.No: T2691

Synonym: 奥利万星二磷酸盐,LY333328 diphosphate

Target: Others, Antibacterial, Antibiotic

Cat.No: T77521

Target: Antibacterial

Cat.No: T22279

Target: CRISPR/Cas9

6'-hydroxydihydrocinchonidine

Cat.No: T77551

Target: Antibiotic, Drug Metabolite

Cat.No: T0331L

Synonym: Avelox,Moxeza,莫西沙星

Target: Others, Antibacterial, Antibiotic

Cat.No: T4063

Synonym: ABT492,WQ-3034,德拉沙星,RX-3341

Target: Antibacterial, Antibiotic

3,5-Dimethylbenzaldehyde

Cat.No: T38137

Target: Endogenous Metabolite, Antifungal

Cat.No: T14386

Synonym: Mizacorat

Target: Glucocorticoid Receptor

Faropenem daloxate

Cat.No: T11265

Synonym: 法罗培南酯,Faropenem medoxil

Target: Antibacterial, Antibiotic

Cat.No: T7872

Target: Others

Cat.No: T77633

Synonym: G 43,G-43

Target: Antibacterial, Transferase

Cat.No: T2331

Synonym: 索利霉素,OP-1068,CEM-101

Target: Antibacterial, Antibiotic

Gemifloxacin mesylate

Cat.No: T1492

Synonym: LB-20304a,甲磺酸吉米沙星,SB-265805S,Gemifloxacin mesylate

Target: DNA gyrase, Topoisomerase, Antibacterial

Cat.No: T0391

Synonym: PNU-100766,雷奈佐利

Target: MAO, Antibacterial, Antibiotic

Ethylhydrocupreine hydrochloride

Cat.No: T40417

Synonym: Optochin hydrochloride,乙氢去甲奎宁盐酸盐；奥普托欣盐酸盐

Target: Antibacterial, Parasite

Cat.No: T28209

Target: Others

Cat.No: T34318

Synonym: Formylpteroic acid

Target: Others

Cat.No: T32990

Synonym: LY164846,LY-164846,7-Bgmcc

Target: Others

（4R，9S)-AG 205

Cat.No: T70835

Target: Others

Competence-Stimulating Peptide-2 (CSP-2)

Cat.No: T38559

Omadacycline mesylate

Cat.No: T5189L

Synonym: PTK 0796,PTK-0796,PTK0796

Target: Others

Cat.No: T25767

Synonym: Katanosin A, 7-L-isoleucine-,Katanosin B

Zabofloxacin hydrochloride

Cat.No: T13406L

Synonym: DW-224a

Target: Raf

Cat.No: T70878

Target: Others

Cat.No: T13406

Synonym: DW-224a Free base

Target: Others

8-Deazafolic acid

Cat.No: T24990

Synonym: NSC-173522,NSC173522,NSC 173522

Target: Others

Cat.No: TP1358

Acetyl-Adhesin (1025-1044) amide

Cat.No: T76467

Brilacidin tetrahydrochloride

Cat.No: T38608

Synonym: PMX 30063 tetrahydrochloride

Target: Others

Cat.No: T80317

Cat.No: T38586

Synonym: dl-Grepafloxacin,OPC-17116

Target: Others

Cat.No: T30481

Synonym: BK218,BK-218

Target: Others

Cat.No: T80280

Cat.No: T30311

Synonym: REP 8839,REP-8839,REP8839

Target: Antibacterial

Cat.No: T28311

Synonym: PD116,152,PD 116,152,PD116152,PD-116,152,PD-116152

Target: Others

Cat.No: T81071

Target: ADC Cytotoxin

Cat.No: T81737

Target: Others

Cat.No: T80252

Erythromycin lactobionate

Cat.No: T37433

Target: Others

Cat.No: T28314

Synonym: PD117588,PD-117588

Target: Others

Cat.No: T84965

Target: Others

Erythromycin A N-oxide

Cat.No: T37432

Target: Others

Omadacycline HCl

Cat.No: T71266

Target: Others

Deethylindanomycin

Cat.No: T35731

Target: Others

Ceftaroline fosamil (hydrate)(acetate)

Cat.No: T74591

Target: Others

VEGFR-2/DHFR-IN-1

Cat.No: T61489

Target: Others

Cat.No: T36409

Target: Others

Cat. No.	Product Name	Target	Signaling Pathways
TN1774	Isobavachromene	Others; Antibacterial	Microbiology/Virology; Others
	Isobavachromene 是一种抗菌剂。
T3866	Macelignan 安五脂素,Anwuligan,(+)-Anwulignan	Others; COX	Immunology/Inflammation; Neuroscience; Others
	Macelignan (Anwuligan) 是一种从肉豆蔻中分离得到的木脂素，具有抗炎、抗癌、抗糖尿病和神经保护活性。
T7999	7-Hydroxyflavanone	Anti-infection	Microbiology/Virology
	7-Hydroxyflavanone 对肺炎链球菌临床分离株显示出抗菌活性。
T10933	D-Cysteine	Endogenous Metabolite; Antibacterial	Metabolism; Microbiology/Virology
	D-Cysteine 是一种大肠杆菌生长的有力抑制剂，是半胱氨酸的 D 型异构体。它由 D-氨基酸氧化酶介导产生 H2S，是一种对抗小脑共济失调的神经保护剂。 D-半胱氨酸可以抑制由变形链球菌和链球菌血红蛋白形成的两种生物膜的生长和致龋性。
T12830	Sapienic acid sodium	Antibacterial	Microbiology/Virology
	Sapienic acid sodium，主要存在于皮肤和粘膜中的脂肪酸，对皮肤和口腔内的革兰氏阳性及阴性细菌展现出不同程度的抗菌效果。其对血链球菌、微生物链球菌与核纤梭菌的抗菌活性表现，MBC值分别为31.3 μg/mL、375.0 μg/mL与93.8 μg/mL。
T12830L	Sapienic acid	Others	Others
	Sapienic acid is a fatty acid commonly found on the skin and in the mucosa. Sapienic acid is active against Streptococcus sanguinis, Streptococcus mitis, and Fusobacterium nucleatum with MBC values of 31.3 μg/mL, 375.0 μg/mL and 93.8 μg/mL, respectively.
TN3995	Erythrabyssin II	Antifection	Microbiology/Virology
	Erythrabyssin II actives against several strains of Staphylococcus and Streptococcus with an MIC range of 0.78-1.56 microg/ml. It inhibits bacterial neuraminidase in a dose-dependent manner with significant inhibition (IC(50)=0.09-3.25 μM).
TN4097	Gancaonin G	Antifection	Microbiology/Virology
	Gancaonin G shows antibacterial effects on the MRSA strains with MIC values of 16 microg/ml, it also shows more moderate antibacterial activity against Streptococcus mutans.
TN1409	Asimilobine	AChR; Antifection	Microbiology/Virology; Neuroscience
	(-)-Asimilobine shows antioxidative, anti-acetylcholinesterase (AChE), anti-α±-glucosidase, anti-leishmanial and anti-fungal activities; it displays weak inhibition against Streptococcus mutans (ATCC 25175), with a minimum inhibition concentration (MIC) o
TN4840	Psoromic acid	Others	Others
	Psoromic acid is a selective and covalent rab-prenylation inhibitor targeting autoinhibited RabGGTase, it shows antibacterial activities against Streptococcus gordonii and Porphyromonas gingivalis, and it is an effective and safe natural drug plausible fo
T38706	Erlose	Others	Others
	Erlose, a trisaccharide present in soybean aphid honeydew and composed of sucrose, acts as a sweetener substitute to inhibit dental caries formation by oral microorganisms, primarily Streptococcus mutans. Erlose can serve as a reference compound in high-performance liquid chromatography (HPLC) methods employed for the analysis of sugar content in various food samples.
TN4399	Kushenol C	SGLT; NF-κB; ROS; BACE; Antifection	GPCR/G Protein; Immunology/Inflammation; Microbiology/Virology; Neuroscience; NF-κB
	Kushenol C is a good 1,1-diphenyl-2-picrylhydrazyl (DPPH) scavenger, and it exhibits inhibitory activity against Sodium-dependent glucose cotransporter 2(SGLT2). Kushenol C shows antimicrobial activity against Staphylococcus aureus and Streptococcus mutan
TN7324	(±)-ε-Viniferin	Others	Others
	(±)-ε-Viniferin，ε-Viniferin的外消旋体，展现P450抑制性抗氧化、保肝及抗菌特性。该化合物对革兰氏阳性菌肺炎链球菌显示出抗菌和抗生物膜活性，最小抑制浓度（MIC）为20 μM。
T79993	Oleanolic aldehyde	Others	Others
	Oleanolic aldehyde 是一种具有抗菌性质的化合物，能够抑制口腔内细菌生长。该化合物对变形链球菌和牙龈卟啉单胞菌——与龋齿和牙周病有关的细菌——显示出显著的抑制效果，其最低抑菌浓度(MICs)分别为488 μg/mL和250 μg/mL。
TN4471	Lysicamine	IL Receptor; Antifection	Immunology/Inflammation; Microbiology/Virology
	Lysicamine shows significant antioxidant capacity in the ORAC(FL) assay and it is active against S. epidermidis and C. dubliniensis, with MIC values in the range 12.5-100 microg mL(-1). Lysicamine has antimicrobial and anti-inflammation activity, the mini

天然产物

Isobavachromene

Cat.No: TN1774

Target: Others, Antibacterial

Cat.No: T3866

Synonym: 安五脂素,Anwuligan,(+)-Anwulignan

Target: Others, COX

7-Hydroxyflavanone

Cat.No: T7999

Target: Anti-infection

Cat.No: T10933

Target: Endogenous Metabolite, Antibacterial

Sapienic acid sodium

Cat.No: T12830

Target: Antibacterial

Cat.No: T12830L

Target: Others

Erythrabyssin II

Cat.No: TN3995

Target: Antifection

Cat.No: TN4097

Target: Antifection

Cat.No: TN1409

Target: AChR, Antifection

Cat.No: TN4840

Target: Others

Cat.No: T38706

Target: Others

Cat.No: TN4399

Target: SGLT, NF-κB, ROS, BACE, Antifection

(±)-ε-Viniferin

Cat.No: TN7324

Target: Others

Oleanolic aldehyde

Cat.No: T79993

Target: Others

Cat.No: TN4471

Target: IL Receptor, Antifection

Species：

Expression System：

Tag：

Cat. No.	Product Name	Species	Expression System
TMPY-05346	CRISPR-Cas9 Protein, Streptococcus pyogenes, Recombinant (His) SpyCas9	Streptococcus pyogenes	Baculovirus Insect Cells
	CRISPR-Cas9 Protein, Streptococcus pyogenes, Recombinant (His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 163 kDa and the accession number is Q99ZW2.
TMPY-06023	IdeS Protein, Streptococcus pyogenes, Recombinant (His)	Streptococcus pyogenes	E. coli
	IdeS (IgG-degrading enzyme of Streptococcus pyogenes) is a secreted cysteine endopeptidase from the human pathogen S. pyogenes with an extraordinarily high degree of substrate specificity, catalyzing a single proteolytic cleavage at the lower hinge of human IgG. This proteolytic degradation promotes inhibition of opsonophagocytosis and interferes with the killing of group A Streptococcus. IdeS Protein, Streptococcus pyogenes, Recombinant (His) is expressed in E. coli expression system with His t...
TMPY-06179	IdeS Protein, Streptococcus pyogenes, Recombinant (His & GST)	Streptococcus pyogenes	E. coli
	IdeS (IgG-degrading enzyme of Streptococcus pyogenes) is a secreted cysteine endopeptidase from the human pathogen S. pyogenes with an extraordinarily high degree of substrate specificity, catalyzing a single proteolytic cleavage at the lower hinge of human IgG. This proteolytic degradation promotes inhibition of opsonophagocytosis and interferes with the killing of group A Streptococcus. IdeS Protein, Streptococcus pyogenes, Recombinant (His & GST) is expressed in E. coli expression system with...
TMPH-03598	Streptopain Protein, S. pyogenes serotype M28, Recombinant (His & SUMO) SPE B,Streptococcus peptidase A,Streptopain,Strepto...	Streptococcus pyogenes	E. coli
	Important streptococcal virulence factor which cleaves human fibronectin and degrades vitronectin. Also cleaves human IL1B precursor to form biologically active IL1B. Can induce apoptosis in human monocytes and epithelial cells in vitro, and reduces phagocytic activity in monocytic cells. Thus, may play a role in bacterial colonization, invasion, and inhibition of wound healing. Streptopain Protein, S. pyogenes serotype M28, Recombinant (His & SUMO) is expressed in E. coli expression system with...
TMPH-03599	Streptopain Protein, S. pyogenes, Recombinant (His & SUMO) Group A streptococcal cysteine protease,SPE B,Streptococ...	Streptococcus pyogenes	E. coli
	Important streptococcal virulence factor which cleaves human fibronectin and degrades vitronectin. Also cleaves human IL1B precursor to form biologically active IL1B. Can induce apoptosis in human monocytes and epithelial cells in vitro, and reduces phagocytic activity in monocytic cells. Thus, may play a role in bacterial colonization, invasion, and inhibition of wound healing. Streptopain Protein, S. pyogenes, Recombinant (His & SUMO) is expressed in E. coli expression system with N-6xHis-SUMO...
TMPY-06476	CAMP Factor Protein, Cutibacterium acnes, Recombinant (His)	Cutibacterium acnes	Baculovirus Insect Cells
	CAMP factor is an extracellular cytolytic protein produced by Streptococcus agalactiae. CAMP factor binds the Fc fragments of IgG and is also known as protein B, in analogy to protein A of Staphylococcus aureus.
TMPK-00720	Siglec-5 Protein (Primary Amine Labeling), Human, Recombinant (hFc), Biotinylated CD170,CD33 antigen-like 2,OBBP2,SIGLEC5,OB-BP2,CD33L2	Human	HEK293 Cells
	Group B Streptococcus (GBS) causes invasive infections in human newborns. the GBS β-protein attenuates innate immune responses by binding to sialic acid-binding immunoglobulin-like lectin 5 (Siglec-5), an inhibitory receptor on phagocytes.the polymorphism could influence the risk of prematurity among human fetuses of mothers colonized with GBS. This first functionally proven example of a paired receptor system in the Siglec family has multiple implications for regulation of host immunity.
TMPH-03595	APT Protein, S. pyogenes serotype M1, Recombinant (His & Myc) Adenine phosphoribosyltransferase,apt,APRT	Streptococcus pyogenes	P. pastoris (Yeast)
	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. APT Protein, S. pyogenes serotype M1, Recombinant (His & Myc) is expressed in yeast with N-10xHis and C-Myc tag. The predicted molecular weight is 22.7 kDa and the accession number is P63546.
TMPH-03593	Pneumolysin Protein, S. pneumoniae serotype 4, Recombinant (Avi & His) Thiol-activated cytolysin,Pneumolysin,ply	Streptococcus pneumoniae	E. coli
	A cholesterol-dependent toxin that causes cytolysis by forming pores in cholesterol containing host membranes. After binding to target membranes, the protein undergoes a major conformation change, leading to its insertion in the host membrane and formation of an oligomeric pore complex. Cholesterol is required for binding to host membranes, membrane insertion and pore formation; cholesterol binding is mediated by a Thr-Leu pair in the C-terminus. Can be reversibly inactivated by oxidation. Pneum...
TMPH-03591	PsaA Protein, S. pneumoniae, Recombinant (His & Myc) Manganese ABC transporter substrate-binding lipoprotein PsaA...	Streptococcus pneumoniae	E. coli
	Part of an ABC transporter complex involved in manganese import. PsaA Protein, S. pneumoniae, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 39.9 kDa and the accession number is P42363.
TMPH-03588	ComC Protein, S. mitis, Recombinant (His & KSI) comC,CSP,Competence-stimulating peptide	Streptococcus mitis	E. coli
	Acts as a pheromone, induces cells to develop competence for genetic transformation. ComC Protein, S. mitis, Recombinant (His & KSI) is expressed in E. coli expression system with N-6xHis-KSI tag. The predicted molecular weight is 17.3 kDa and the accession number is O33666.
TMPH-03592	Pneumolysin Protein, S. pneumoniae serotype 4, Recombinant (His) Thiol-activated cytolysin,ply,Pneumolysin	Streptococcus pneumoniae	P. pastoris (Yeast)
	A cholesterol-dependent toxin that causes cytolysis by forming pores in cholesterol containing host membranes. After binding to target membranes, the protein undergoes a major conformation change, leading to its insertion in the host membrane and formation of an oligomeric pore complex. Cholesterol is required for binding to host membranes, membrane insertion and pore formation; cholesterol binding is mediated by a Thr-Leu pair in the C-terminus. Can be reversibly inactivated by oxidation. Pneum...
TMPH-03586	Toxin zeta Protein, S. agalactiae, Recombinant (His) Toxin zeta,UDP-N-acetylglucosamine kinase	Streptococcus agalactiae	P. pastoris (Yeast)
	Toxic component of a type II toxin-antitoxin (TA) system. Phosphorylates UDP-N-acetyl-D-glucosamine (UNAG) on the 3'-hydroxyl group of the N-acetyl-D-glucosamine moiety, yielding UNAG-3P. UNAG-3P inhibits MurA, the first committed step in cell wall synthesis, which is then blocked. Phosphorylation is inhibited by cognate epsilon antitoxin. Part of a postsegregational killing (PSK) system involved in the killing of plasmid-free cells. The zeta toxin induces programmed cell death. Toxin zeta Prote...
TMPH-03589	PsaA Protein, S. oralis, Recombinant (His & Myc) Manganese ABC transporter substrate-binding lipoprotein PsaA...	Streptococcus oralis	E. coli
	Part of an ATP-driven transport system. PsaA Protein, S. oralis, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 40.1 kDa and the accession number is Q9L5W9.
TMPH-03594	Exotoxin type A Protein, S. pyogenes, Recombinant (His & SUMO) SPE A,Scarlet fever toxin,Exotoxin type A,speA,Erythrogenic ...	Streptococcus pyogenes	E. coli
	Causative agent of the symptoms associated with scarlet fever, have been associated with streptococcal toxic shock-like disease and may play a role in the early events of rheumatic fever. Exotoxin type A Protein, S. pyogenes, Recombinant (His & SUMO) is expressed in E. coli expression system with N-6xHis-SUMO tag. The predicted molecular weight is 38.6 kDa and the accession number is P0DJY7.
TMPH-03596	Holo-ACP synthase Protein, S. pyogenes serotype M28, Recombinant (His & Myc) acpS,4'-phosphopantetheinyl transferase AcpS,Holo-[acyl-carr...	Streptococcus pyogenes	Baculovirus Insect Cells
	Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein. Holo-ACP synthase Protein, S. pyogenes serotype M28, Recombinant (His & Myc) is expressed in Baculovirus insect cells with N-10xHis and C-Myc tag. The predicted molecular weight is 17.1 kDa and the accession number is Q48RM7.
TMPH-03587	GspB Protein, S. gordonii, Recombinant (GST) Serine-rich adhesin for platelets,Serine-rich repeat protein...	Streptococcus gordonii	E. coli
	Plays a role in virulence and host-pathogen interactions. Mediates binding to human platelets via interaction with the human cell surface glycoprotein GP1BA. Plays a positive role in biofilm formation, possibly by self-association via the basic region (BR). GspB Protein, S. gordonii, Recombinant (GST) is expressed in E. coli expression system with N-GST tag. The predicted molecular weight is 68.5 kDa and the accession number is Q939N5.
TMPH-03590	PsaA Protein, S. pneumoniae (strain ATCC BAA-255/R6), Recombinant (His & Myc) psaA,Manganese ABC transporter substrate-binding lipoprotein...	Streptococcus pneumoniae	E. coli
	Part of an ATP-driven transport system. PsaA Protein, S. pneumoniae (strain ATCC BAA-255/R6), Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 40.0 kDa and the accession number is P0A4G3.
TMPH-03597	Holo-ACP synthase Protein, S. pyogenes serotype M28, Recombinant (E. coli, His & Myc) 4'-phosphopantetheinyl transferase AcpS,Holo-[acyl-carrier-p...	Streptococcus pyogenes	E. coli
	Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein. Holo-ACP synthase Protein, S. pyogenes serotype M28, Recombinant (E. coli, His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 18.3 kDa and the accession number is Q48RM7.
TMPH-03600	Glucosyltransferase-SI Protein, S. mutans serotype c, Recombinant (His & Myc) gtfC,Glucosyltransferase-SI,Dextransucrase,Sucrose 6-glucosy...	Streptococcus mutans	E. coli
	Production of extracellular glucans, that are thought to play a key role in the development of the dental plaque because of their ability to adhere to smooth surfaces and mediate the aggregation of bacterial cells and food debris. Glucosyltransferase-SI Protein, S. mutans serotype c, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 26.7 kDa and the accession number is P13470.

重组蛋白

CRISPR-Cas9 Protein, Streptococcus pyogenes, Recombinant (His)

Cat.No: TMPY-05346

Species: Streptococcus pyogenes

Expression System: Baculovirus Insect Cells

IdeS Protein, Streptococcus pyogenes, Recombinant (His)

Cat.No: TMPY-06023

Species: Streptococcus pyogenes

Expression System: E. coli

IdeS Protein, Streptococcus pyogenes, Recombinant (His & GST)

Cat.No: TMPY-06179

Species: Streptococcus pyogenes

Expression System: E. coli

Streptopain Protein, S. pyogenes serotype M28, Recombinant (His & SUMO)

Cat.No: TMPH-03598

Species: Streptococcus pyogenes

Expression System: E. coli

Streptopain Protein, S. pyogenes, Recombinant (His & SUMO)

Cat.No: TMPH-03599

Species: Streptococcus pyogenes

Expression System: E. coli

CAMP Factor Protein, Cutibacterium acnes, Recombinant (His)

Cat.No: TMPY-06476

Species: Cutibacterium acnes

Expression System: Baculovirus Insect Cells

Siglec-5 Protein (Primary Amine Labeling), Human, Recombinant (hFc), Biotinylated

Cat.No: TMPK-00720

Species: Human

Expression System: HEK293 Cells

APT Protein, S. pyogenes serotype M1, Recombinant (His & Myc)

Cat.No: TMPH-03595

Species: Streptococcus pyogenes

Expression System: P. pastoris (Yeast)

Pneumolysin Protein, S. pneumoniae serotype 4, Recombinant (Avi & His)

Cat.No: TMPH-03593

Species: Streptococcus pneumoniae

Expression System: E. coli

PsaA Protein, S. pneumoniae, Recombinant (His & Myc)

Cat.No: TMPH-03591

Species: Streptococcus pneumoniae

Expression System: E. coli

ComC Protein, S. mitis, Recombinant (His & KSI)

Cat.No: TMPH-03588

Species: Streptococcus mitis

Expression System: E. coli

Pneumolysin Protein, S. pneumoniae serotype 4, Recombinant (His)

Cat.No: TMPH-03592

Species: Streptococcus pneumoniae

Expression System: P. pastoris (Yeast)

Toxin zeta Protein, S. agalactiae, Recombinant (His)

Cat.No: TMPH-03586

Species: Streptococcus agalactiae

Expression System: P. pastoris (Yeast)

PsaA Protein, S. oralis, Recombinant (His & Myc)

Cat.No: TMPH-03589

Species: Streptococcus oralis

Expression System: E. coli

Exotoxin type A Protein, S. pyogenes, Recombinant (His & SUMO)

Cat.No: TMPH-03594

Species: Streptococcus pyogenes

Expression System: E. coli

Holo-ACP synthase Protein, S. pyogenes serotype M28, Recombinant (His & Myc)

Cat.No: TMPH-03596

Species: Streptococcus pyogenes

Expression System: Baculovirus Insect Cells

GspB Protein, S. gordonii, Recombinant (GST)

Cat.No: TMPH-03587

Species: Streptococcus gordonii

Expression System: E. coli

PsaA Protein, S. pneumoniae (strain ATCC BAA-255/R6), Recombinant (His & Myc)

Cat.No: TMPH-03590

Species: Streptococcus pneumoniae

Expression System: E. coli

Holo-ACP synthase Protein, S. pyogenes serotype M28, Recombinant (E. coli, His & Myc)

Cat.No: TMPH-03597

Species: Streptococcus pyogenes

Expression System: E. coli

Glucosyltransferase-SI Protein, S. mutans serotype c, Recombinant (His & Myc)

Cat.No: TMPH-03600

Species: Streptococcus mutans

Expression System: E. coli

Cat. No.	Product Name	Target	Signaling Pathways
TMIJ-0059	Moxifloxacin-d4
	Moxifloxacin-d4 是 Moxifloxacin 的氘代化合物。Moxifloxacin 的 CAS 号为 151096-09-2。Moxifloxacin 是一种8-甲氧基喹诺酮类口服有效抗菌药物，用于急性细菌性鼻窦炎，慢性支气管炎的急性细菌性加重和感染性肺炎的研究。
TMID-0281	Moxifloxacin-13C-d3
	Moxifloxacin-13C-d3 是 Moxifloxacin 的 13C 和氘代化合物。Moxifloxacin 的 CAS 号为 151096-09-2。Moxifloxacin 是一种8-甲氧基喹诺酮类口服有效抗菌药物，用于急性细菌性鼻窦炎，慢性支气管炎的急性细菌性加重和感染性肺炎的研究。

同位素标记化合物

Moxifloxacin-d4

Cat.No: TMIJ-0059

Moxifloxacin-13C-d3

Cat.No: TMID-0281

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