130
93
69
Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T5038 |
Cephapirin Sodium
|
Antibacterial; Antibiotic | Microbiology/Virology |
Cephapirin sodium 是一种半合成头孢菌素类抗生素,对革兰氏阳性菌和革兰氏阴性菌有杀菌作用。 | |||
T1224 |
Cefuroxime sodium
Anaptivan,头孢呋辛钠,Cefuroxime sodium salt,Biociclin |
Antibacterial; Antibiotic | Microbiology/Virology |
Cefuroxime sodium (Cefuroxime sodium salt) 是一种具有口服活性的头孢菌素抗生素,增加了对 β-内酰胺酶的稳定性。 | |||
T19717 |
Cyclo-L-Trp-L-Trp
|
Antifungal | Microbiology/Virology |
Cyclo-L-Trp-L-Trp 是一种广谱抗真菌剂。它还诱导组蛋白的高度乙酰化。 | |||
T80707 |
α-Hemolysin (Staphylococcus aureus)
|
||
α-Hemolysin (Staphylococcus aureus) 是一种由金黄色葡萄球菌分泌的毒力因子,具有破坏宿主细胞质膜的多肽特性。α-Hemolysin 绑定细胞表面后,通过其单体组装成同型七聚体预孔结构,并转变为成熟的跨膜孔,形成水通道。这一过程促使 K+ 和 Ca2+ 离子通过膜,触发靶细胞的坏死性死亡。 | |||
T1440 |
Ethacridine lactate monohydrate
乳酸依沙吖啶一水物,利凡诺 |
Antibacterial; Antibiotic | Microbiology/Virology |
Ethacridine lactate monohydrate 是一种聚 (ADP-核糖) 糖基水解酶 (PARG) 抑制剂,有抗金黄色葡萄球菌和其他革兰氏阳性球菌的活性。它也是抗菌剂和流产剂。 | |||
T5967 |
Ethacridine lactate
乳酸依沙吖啶,Acrinol,6,9-DIAMINO-2-ETHOXYACRIDINE LACTATE |
Others; Antibacterial | Microbiology/Virology; Others |
Ethacridine lactate (Acrinol) 是一种聚 (ADP-核糖) 糖水解酶 (PARG) 抑制剂,也是一种抗菌剂和流产剂。它有抗金黄色葡萄球菌和其他革兰氏阳性球菌的活性。 | |||
T21358 |
Dalbavancin
BI 397,BI-397,VER 001,A-A 1,BI397,VER-001,Dalbavancin HCl,达巴万星 |
Antibacterial; Antibiotic | Microbiology/Virology |
Dalbavancin (BI-397) HCl 是一种半合成的脂糖肽抗生素,对革兰氏阳性细菌有杀菌活性。Dalbavancin 抑制金黄色葡萄球菌和炭疽芽孢杆菌的 MIC90分别为 0.06 μg/mL 和 0.25 μg/mL。 | |||
T60093 |
CHEMBL1380345
N,N'-(Ethane-1,2-diyl)bis(3-methylbenzenesulfonamide) |
Antibacterial | Microbiology/Virology |
CHEMBL1380345 对金黄色葡萄球菌、蜡状芽孢杆菌和大肠杆菌具有抗菌活性,pMIC 值分别为 3.64、3.56 和 3.70。 | |||
T33470 |
Monoctanoin
辛酸2,3-二羟基酯,Glyceryl 1-caprylate,Moctanin |
Antibacterial | Microbiology/Virology |
Monoctanoin (Glyceryl 1-caprylate) 对金黄色葡萄球菌和大肠杆菌具有抗菌活性。 | |||
T17254 |
Amifloxacin
Win49375,氨氟沙星 |
Antibacterial | Microbiology/Virology |
Amifloxacin (Win49375) 是有效的喹诺酮类抗菌剂。 | |||
T71699 |
Lanopepden mesylate
GSK 1322322 mesylate,GSK-1322322J mesylate |
Antibacterial | Microbiology/Virology |
Lanopepden mesylate 是一种肽去甲酰酶抑制剂,可抑制金黄色葡萄球菌。 | |||
TQ0077 |
Ceftobiprole
Ro 63-9141,BAL 9141,头孢吡普 |
Antibacterial | Microbiology/Virology |
Ceftobiprole (Ro 63-9141) 是一种广谱头孢菌素,对甲氧西林耐受的金黄色葡萄球菌的MIC90值为 2 μg/mL。 | |||
T40475 |
Ceftobiprole medocaril
BAL5788,头孢比普酯 |
Antibacterial | Microbiology/Virology |
Ceftobiprole medocaril (BAL5788) 是 Ceftobiprole 的前药。Ceftobiprole 是一种广谱的头孢菌素,对耐甲氧西林金黄色葡萄球菌具有活性。 | |||
T4105 |
AFN-1252
Debio 1452,API-1252 |
Others; Antibacterial; Antibiotic | Microbiology/Virology; Others |
AFN-1252 (Debio 1452)是一种FabI 的高效抑制剂,能抑制金黄色葡萄球菌。 | |||
T77686 |
1-(4-AMinophenyl)-5,6-dihydro-3-(4-Morpholinyl)-2(1h)-pyridinone
|
Antifungal | Microbiology/Virology |
1-(4-AMinophenyl)-5,6-dihydro-3-(4-Morpholinyl)-2(1h)-pyridinone 具有广谱的抗真菌活性,对白色念珠菌、黑曲霉、铜绿假单胞菌、金黄色葡萄球菌等具有抑制作用。 | |||
T2331 |
Solithromycin
索利霉素,OP-1068,CEM-101 |
Antibacterial; Antibiotic | Microbiology/Virology |
Solithromycin (OP-1068) 是口服可生物利用的抗菌剂,抑制肺炎链球菌、葡萄球菌、金黄色葡萄球菌和流感嗜血杆菌的细胞活力、蛋白质合成和生长速率, IC50 值分别为 7.5 ng/mL、40 ng/mL 和 125 ng/mL。它可与核糖体的大 50S 亚基结合抑制蛋白质生物合成。 | |||
T0391 |
Linezolid
PNU-100766,雷奈佐利 |
MAO; Antibacterial; Antibiotic | Metabolism; Microbiology/Virology; Neuroscience |
Linezolid (PNU-100766) 是恶唑烷酮类合成抗生素,抑制细菌蛋白质合成的起始阶段,具有抗感染作用。 | |||
T38137 |
3,5-Dimethylbenzaldehyde
|
Endogenous Metabolite; Antifungal | Metabolism; Microbiology/Virology |
3,5-Dimethylbenzaldehyde 具有广谱的抗菌活性,对枯草芽孢杆菌、白假丝酵母菌、大肠杆菌、铜绿假单胞菌、金黄色葡萄杆菌和肺炎链球菌具有抑制作用。 | |||
T64316 |
VP-4604
1-((4-Nitrophenyl)sulfonyl)piperidine |
Others | Others |
VP-4604是一种有效的抗耐甲氧西林金黄色葡萄球菌(MRSA)化合物。VP-4604对金黄色葡萄球菌展现出显著的抑制微生物生长的作用,MIC 为4-8μg/mL。VP-4604抑制耐甲氧西林金黄色葡萄球菌的生长,其生长抑制率达到95%以上。 | |||
T11815 |
Lanopepden
GSK 1322322,GSK-1322322B,GSK-1322322J |
Antibiotic | Microbiology/Virology |
Lanopepden (GSK 1322322) 是一种有效的肽去甲酰酶抑制剂,抑制金黄色葡萄球菌,抑制 ATCC 29213 和 ATCC 25923 菌株,可用于研究肺炎、皮肤病和传染病。 | |||
T22269 |
Benzyldodecyldimethylammonium Chloride Dihydrate
|
Antibacterial | Microbiology/Virology |
Benzyldodecyldimethylammonium chloride dihydrate 可以用作杀虫试剂,可以靶向耐药性细菌,如耐甲氧西林金黄色葡萄球菌、耐多药铜绿假单胞菌等,且具有浓度依赖性。 | |||
T63390L |
(S,S)-TAPI-1 FA
(S,S)-TAPI-1 FA(171235-71-5 Free base) |
TNF | Apoptosis |
(S,S)-TAPI-1 FA是 TNF-α加工抑制剂,具有潜在抗炎作用,可阻断 TACE,可抑制 TNF-α 信号传导可用于研究金黄色葡萄球菌关节炎。 | |||
T1492 |
Gemifloxacin mesylate
LB-20304a,甲磺酸吉米沙星,SB-265805S,Gemifloxacin mesylate |
DNA gyrase; Topoisomerase; Antibacterial | DNA Damage/DNA Repair; Microbiology/Virology |
Gemifloxacin mesylate (Gemifloxacin mesylate) 是一种喹诺酮类口服广谱抗菌剂,可研究轻中度肺炎和慢性支气管炎的急性细菌性发作。 | |||
T50004 |
Phentolamine acetate
3-[(4,5-dihydro-1H-imidazol-2-ylmethyl)(4-methylphenyl)amino]phenol acetic acid |
Others | Others |
Phentolamine acetate (3-[(4,5-dihydro-1H-imidazol-2-ylmethyl)(4-methylphenyl)amino]phenol acetic acid) 是一种化合物,它在体外已被证明具有抗炎和抗癌特性,还被证明可以抑制某些细菌的生长,包括金黄色葡萄球菌。 | |||
T61042 |
TBT1
|
Antibacterial | Microbiology/Virology |
TBT1 是一种新型 MsbA 转运蛋白抑制剂,也是 MsbA ATPase 刺激剂,抑制脂多糖合成途径中ATP依赖性转运蛋白的合成。TBT1 具有抗菌活性,抑制沙门氏菌、铜绿假单胞菌、大肠杆菌和金黄色葡萄球菌,可用于研究细菌感染。 | |||
T77608 |
1H-Indole, 3,3'-(2-thienylmethylene)bis[2-methyl-
|
Antifungal | Microbiology/Virology |
1H-Indole, 3,3'-(2-thienylmethylene)bis[2-methyl- 可作为一种广谱抗菌剂,对黑曲霉枯草芽孢杆菌、白假丝酵母、大肠杆菌和金黄色葡萄球菌有抑制作用。1H-Indole, 3,3'-(2-thienylmethylene)bis[2-methyl- 在体外实验中显示出抗炎活性,可用于治疗细菌感染。 | |||
T4165 |
Delpazolid
LCB01-0371 |
Antibacterial; Antibiotic | Microbiology/Virology |
Delpazolid (LCB01-0371) 是一种恶唑烷酮类新型抗生素,能抑制MSSA 和MRSA 的生长,对它们的MIC90值都为 2 μg/mL。 | |||
T22297 |
Clindamycin hydrochloride monohydrate
Clindamycin alcoholate |
Antibiotic | Microbiology/Virology |
Clindamycin hydrochloride monohydrate(Clindamycin alcoholate)是一种口服蛋白质合成抑制剂,具有在金黄色葡萄球菌中以亚抑制浓度(sub-MICs)抑制毒力因子表达的能力。其抗性来源于50S核糖体亚基(23S rRNA)的抗生素结合位点通过酶促甲基化。此外,Clindamycin hydrochloride monohydrate能显著减少杀白细胞毒素(PVL)、毒性休克-葡萄球菌毒素(TSST-1)或α-溶血素(Hla)的产生。 | |||
T82949 |
Atidortoxumab
|
||
Atidortoxumab是针对Staphylococcus aureus alpha毒素的人类IgG1κ单克隆抗体。 | |||
T60525 |
VP-4556
|
Others | Others |
VP-4556 是一种有效的抗耐甲氧西林金黄色葡萄球菌 (MRSA) 剂,对金黄色葡萄球菌 (ATCC 43300) 具有显著的生长抑制作用,MIC 为 8 μg/mL。VP-4556 对于耐甲氧西林金黄色葡萄球菌(MRSA)的生长抑制率达 95% 以上。 | |||
T23871 |
Cefuzonam sodium
CZON,L-105,Cosmosin,CL 251931 sodium salt,L 105 |
Others | Others |
Cefuzonam sodium is a second-generation cephalosporin antibiotic. It may be effective against Staphylococcus aureus against which third-generation cephalosporins are largely ineffective. | |||
T69823 |
MC4
|
Others | Others |
MC4 is a first-in-class inhibitor of ribosomal RNA synthesis with antimicrobial activity against Staphylococcus aureus. | |||
T80323 |
Bovine neutrophil beta-defensin 12
BNBD-12 |
||
Bovine neutrophil beta-defensin 12,一种牛中性粒细胞来源的抗菌肽,展现针对大肠杆菌(Escherichia coli)和金黄色葡萄球菌(Staphylococcus aureus)的抗菌活性。 | |||
T68203 |
Tuberine, (+)-
|
Others | Others |
Tuberine, (+)- is an alkaloid isolated from Haplophyllum tuberculatum that has high antimicrobial activity against Staphylococcus aureus, Bacillus subtilis and Saccharomyces cerevisiae. Tuberine, (+)- is also slightly inhibitory to Escherichia coli . | |||
T80398 |
Brevinin-1PMa
|
||
Brevinin-1PMa为宿主防御肽,对金黄色葡萄球菌(Staphylococcus aureus)和大肠杆菌(Escherichia coli)展现出抗菌活性,并具溶血活性。 | |||
T11062 |
dmDNA31
|
Others | Others |
dmDNA31 is a rifamycin antibiotic that can inhibit the DNA-dependent RNA polymerase of bacteria and has strong bactericidal activity against Staphylococcus aureus. | |||
T81024 |
Tefibazumab
INH-H 2002 |
||
Tefibazumab是一种人源化IgG1κ单克隆抗体,它能特异性结合至金黄色葡萄球菌表面表达的粘附蛋白凝集因子A。该抗体主要用于针对严重金黄色葡萄球菌感染的研究。 | |||
T28898 |
T145
T 145,T-145 |
Others | Others |
T145 inhibits growth of Enterococcus faecalis, Staphylococcus aureus and Mycobacterium tuberculosis (Mtb) with sub μg/ml potencies that are potentially therapeutically valuable. T145 minimizes selection of spontaneous resistant mutants, a trait that prolo | |||
T80317 |
Combi-2
|
||
Combi-2为针对S.aureus、S.sanguis及E.coli具有抗菌活性的肽类化合物。 | |||
T76658 |
SYNV-cyclo(CGGYF)
|
||
SYNV-cyclo(CGGYF),一种源自人葡萄球菌(S. hominis)C5的自诱导肽,能抑制金黄色葡萄球菌(S. aureus)的活性,展现出研究金黄色葡萄球菌引发的上皮损伤及炎症的潜力。 | |||
T15142 |
Vebufloxacin
OPC7241,Flumenique,DM8966 |
Antibacterial | Microbiology/Virology |
Vebufloxacin (OPC-7251) shows potent antibacterial activity against gram-positive and -negative bacteria, including Staphylococcus aureus and Pseudomonas aeruginosa. It has potent activity characteristically against Propionibacterium acnes. | |||
T70436 |
BMS 188745 Potassium Salt
|
Others | Others |
BMS 188745 Potassium Salt inhibits the biosynthesis of the Staphylococcus aureus virulence factor staphyloxanthin via inhibition of dehydrosqualene synthase (CrtM). | |||
T82930 |
Autoinducing Peptide I
|
||
Autoinducing Peptide I为金黄色葡萄球菌分泌的环状八肽,主要用于疫苗研究领域。 | |||
T63064 |
Antibacterial agent 100
|
Others | Others |
Antibacterial agent 100 (Compound 7c) 是一种抗细菌和真菌剂,能够作用于 Staphylococcus aureus (MIC: 4 μg/mL)、Candida albicans (MIC: 4 μg/mL) 和 Cryptococcus neoformans (MIC: 8 μg/mL)。 | |||
T25767 |
Lysobactin
Katanosin A, 7-L-isoleucine-,Katanosin B |
||
Lysobactin, also known as katanosin B, is an effective antibiotic with in vivo efficacy against Staphylococcus aureus and Streptococcus pneumoniae. It was previously shown to inhibit peptidoglycan (PG) biosynthesis. | |||
T79778 |
Anti-MRSA agent 8
|
Others | Others |
Anti-MRSA agent 8(Compound 7g)为DAPG衍生物,展现出显著的抗菌活性,主要通过作用于细菌细胞膜以发挥效能。此化合物可应用于耐甲氧西林Staphylococcus aureus(MRSA)的研究领域。 | |||
T26256 |
Teicoplanin aglycone
TD-A3 |
Others | Others |
Teicoplanin aglycone is an antibacterial glycopeptide antibiotic used in the prophylaxis and treatment of serious infections caused by Gram-positive bacteria, including Enterococcus faecalis and methicillin-resistant Staphylococcus aureus. | |||
T61799 |
Antibacterial agent 75
|
Others | Others |
Antibacterial agent 75 (compound 24) possesses antibacterial properties. Its notable attribute is the ability to re-sensitize VRSA (Vancomycin-Resistant Staphylococcus aureus) strains to vancomycin, as reported in reference [1]. | |||
T21384 |
Dicloxacillin
Dicloxacilina,Dicloxacycline,Dicloxacillinum,Dicloxacilline,Diclocil,Dynapen |
Others | Others |
Dicloxacillin (INN), a narrow-spectrum β-Lactam antibiotic of the penicillin class, is used against beta-lactamase-producing organisms such as Staphylococcus aureus, which would otherwise be resistant to most penicillins. | |||
T33359 |
Meticillin
Staphcillin,Methicillin,Dimethoxyphenyl Penicillin,Metin |
Others | Others |
Methicillin is a narrow-spectrum beta-lactam antibiotic of the penicillin-like family, used to treat infections caused by susceptible gram-positive bacteria, in particular penicillase-producing organisms such as Staphylococcus aureus. |
Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T5780 |
HYPOCRELLIN B
|
Apoptosis; Parasite; Antifungal | Apoptosis; Microbiology/Virology |
Hypocrellin B 是从真菌Hypocrella bambusae 和Shiraia bambusicola 中分离得到的一种感光颜料,可用于癌症光动力研究。它是一个凋亡诱导剂,还拥有抗菌和抗利什曼活性。 | |||
T2904 |
Sclareolide
香紫苏内酯,Norambreinolide |
Others; Antibacterial | Microbiology/Virology; Others |
Sclareolide (Norambreinolide) 是一种从Salvia sclarea 的花中分离得到的天然产物,具有抗菌和细胞毒性作用。 | |||
T4S1114 |
Dryocrassin ABBA
东北贯众素,Dryocrassin |
Influenza Virus; Antibacterial | Microbiology/Virology |
Dryocrassin ABBA (Dryocrassin) 是一种从苦参中提取的黄酮类天然产物,具有抗病毒和抗菌活性。它抑制树突状细胞的免疫刺激功能,延长同种异体皮肤移植成活率。 | |||
T1465 |
Mupirocin
Pseudomonic acid,莫匹罗星,BRL-4910A |
DNA/RNA Synthesis; Antibacterial; Antibiotic | Cell Cycle/Checkpoint; DNA Damage/DNA Repair; Microbiology/Virology |
Mupirocin (BRL-4910A) 是从Pseudomonas fluorescens 中分离得到的一种有口服活性的抗生素。它可逆地抑制异亮氨酸转移RNA,并抑制细菌蛋白和RNA 的合成起抗菌作用。 | |||
T8148 |
Mupirocin calcium hydrate
莫匹罗星钙,Mupirocin calcium |
Others; Antibacterial; Antibiotic | Microbiology/Virology; Others |
Mupirocin calcium hydrate 是从Pseudomonas fluorescens 中分离得到的,一种有口服活性的抗生素。它可逆地抑制异亮氨酸转移RNA,并抑制细菌蛋白和RNA 的合成起到抗菌作用。 | |||
TN1524 |
Continentalic acid
|
NOS; COX; Antibacterial; Prostaglandin Receptor | GPCR/G Protein; Immunology/Inflammation; Microbiology/Virology; Neuroscience |
Continentalic acid 是来自 Aralia continentalis 的,对金黄色葡萄球菌的 MIC 约为 8-16 µg/mL,包括对甲氧西林敏感的金黄色葡萄球菌和耐甲氧西林金黄色葡萄球菌标准菌株。 | |||
TN1527 |
(-)-Corynoxidine
Corynoxidine |
Antibacterial; AChE; Antifection | Microbiology/Virology; Neuroscience |
(-)-Corynoxidine 是一种源自 Stephania succifera 块茎的 AChE 抑制剂。 Corynoxidine 对金黄色葡萄球菌和耐甲氧西林金黄色葡萄球菌具有不同程度的抗菌活性。 | |||
TN4943 |
Sanguisorbigenin
地榆皂苷元,Tomentosolic acid,3β-Hydroxyurs-12,19-dien-28-oic acid,19-Dehydroursolic acid,Ursa-12,19-dien-28-oic acid |
Antibacterial | Microbiology/Virology |
Sanguisorbigenin (Tomentosolic acid) 抑制耐甲氧西林金黄色葡萄球菌,是一种天然抗菌剂。 | |||
TJS0368 |
4-Phenyl-7,8-dihydroxycoumarin
7,8-二羟基-4-苯基香豆素,7,8-Dihydroxy-4-Phenyl-2H-Chromen-2-One,7,8-Dihydroxy-4-phenylcoumarin |
Others | Others |
4-Phenyl-7,8-dihydroxycoumarin (7,8-Dihydroxy-4-phenylcoumarin) 是香豆素衍生物,可用于研究支气管扩张。 | |||
T40646 |
Lipoteichoic acid
|
Complement System | Immunology/Inflammation |
Lipoteichoic acid 是 Staphylococcus aureus 细胞壁的聚合物,通过诱导 C3 和抑制 CD55 来激活补体系统,通过 IGF-1 途径减少脂肪沉积。 | |||
TN6746 |
(-)-TERPINEN-4-OL
|
Antibacterial | Microbiology/Virology |
(-)-TERPINEN-4-OL 可用作抗金黄色葡萄球菌的抗菌剂和抗生物膜剂。 | |||
T37753 |
Aureusimine B
|
Cysteine Protease; Antibacterial | Microbiology/Virology; Proteases/Proteasome |
Aureusimine B 是一种钙蛋白酶抑制剂,由金黄色葡萄球菌生物膜产生,可能是金黄色葡萄球菌生物膜感染的潜在生物标志物。 | |||
TN1041 |
Quercimeritrin
槲皮素-7-O-葡萄糖苷,槲皮素-7-0-葡萄苷,Quercetin-7-O-beta-D-glucopyranoside |
Anti-infection; COX; NO Synthase | Immunology/Inflammation; Microbiology/Virology; Neuroscience |
Quercimeritrin (Quercetin-7-O-beta-D-glucopyranoside) 是分离自齿状苦艾叶中,具淀粉酶作用。 | |||
TN1204 |
2,3-Dehydrokievitone
2,3-脱氢维酮 |
Antifungal | Microbiology/Virology |
2,3-Dehydrokievitone 是一种从刺桐属植物 Erythrina sacleuxii 中提取的一种异黄酮,具有抗菌活性,可通过降低α-溶血素表达来对抗耐甲氧西林金黄色葡萄球菌感染。 | |||
TN7242 |
5-Hydroxyvanillin
3,4-Dihydroxy-5-methoxybenzaldehyde |
Antifungal | Microbiology/Virology |
5-Hydroxyvanillin (3,4-Dihydroxy-5-methoxybenzaldehyde) 可从籼稻中就分离得到对金黄色葡萄球菌具有抑制作用,可用于治疗和预防骨质疏松症。 | |||
T7335 |
2,3-Diaminopropionic acid
L-2,3-二氨基丙酸,L-2,3-Diaminopropionic acid |
Endogenous Metabolite | Metabolism |
2,3-Diaminopropionic acid (L-2,3-Diaminopropionic acid) 是一种神经毒性氨基酸 b-oxalyl-L-a, b-diaminopropionic acid 的代谢产物。 | |||
T3S2381 |
Perillene
3-Isohexenylfuran,紫苏烯,Perillen |
Others; Antibacterial | Microbiology/Virology; Others |
Perillene (3-Isohexenylfuran) 是促进肠蠕动的药物中的活性成分,它对金黄色葡萄球菌和大肠杆菌具有很强的抗药性。 | |||
T21552 |
5-deoxy Thymidine
5'-脱氧胸苷,5'-Deoxythymidine,Thymidine, 5'-deoxy-1-[(2R,4S,5R)-4-hydroxy-5-methyloxolan-2-yl]-5-methylpyrimidine-2,4-dione |
Others | Others |
5-deoxy Thymidine (5'-Deoxythymidine) 是5'位被氢取代的胸苷形式。它对枯草芽孢杆菌和金黄色葡萄球菌的活性有效。 | |||
T13305 |
Viridicatol
|
Anti-infection; Antifungal | Microbiology/Virology |
Viridicatol 是从夹竹桃的内生真菌青霉菌属的发酵中分离出的一种喹诺酮类生物碱,对金黄色葡萄球菌有抗菌活性,MIC 值为 15.6 μg/mL。 | |||
TN7224 |
2,2'-Dihydroxy chalcone
|
Antibacterial; Autophagy | Autophagy; Microbiology/Virology |
2,2'-Dihydroxy chalcone 是一种用 fMLP/CB 刺激的大鼠中性粒细胞释放β-葡糖醛酸酶(IC50=1.6±0.2μM)和溶菌酶(IC50=1.4±0.2μM)的有效抑制剂。2,2'-Dihydroxy chalcone 对大肠杆菌、福氏志贺氏菌、白葡萄球菌和金黄色葡萄球菌有抑菌活性。 | |||
T4S1616 |
Sanggenon D
Sanggenone D |
GABA Receptor; Antibiotic | Membrane transporter/Ion channel; Microbiology/Virology; Neuroscience |
Sanggenon D (Sanggenone D) 是来自桑白皮的小分子化合物,是GABA(A)受体调节剂,具有抗氧化抗菌活性,抑制乳腺癌细胞增殖,通过调节脂肪酸生物合成系统来抑制金黄色葡萄球菌的生长。 | |||
TN1905 |
Magnolioside
七叶苷甲基醚,6-甲氧基香豆素-7-0-BETA-D-吡喃葡萄糖苷 |
Antifection | Microbiology/Virology |
Magnolioside 是分离自Angelica gigas Nakai(Umbelliferae) 中,对谷氨酸诱导的毒性有显著的神经保护作用。 它显示出对金黄色葡萄球菌 CIP 53.154 的中等抗菌活性。它具有抗疟原虫活性,对氯喹敏感的恶性疟原虫菌株具有强烈的生长抑制作用。 | |||
TN1084 |
1,3,5,8-Tetrahydroxyxanthone
Desmethylbellidifolin,去甲基雏叶龙胆酮 |
Anti-infection | Microbiology/Virology |
1,3,5,8-Tetrahydroxyxanthone (Desmethylbellidifolin) 是一种天然黄酮,从 Gentianella acuta 中提取得到。它具有镇痉作用和抗炎作用。 | |||
T8724 |
6-Methoxydihydrosanguinarine
|
Others | Others |
6-Methoxydihydrosanguinarine 是一种从M. cordata 果实中分离出的生物碱,它对 MCF-7 细胞系(IC50:0.61 μM)和 SF-268 细胞系(IC50:0.54 μM)具有强的细胞毒性。 | |||
T70955 |
Vinaxanthone
SM-345431 |
Phospholipase; Antibacterial | Metabolism; Microbiology/Virology |
Vinaxanthone (SM-345431) 是一种从青霉菌中提取的小分子化合物,是一种具有选择性和有效性的 semaphorin3A、phospholipase C (PLC) 和 FabI 抑制剂,抑制semaphorin3A 和 FabI。Vinaxanthone 具有抗菌活性,阻止细胞内脂肪酸合成,抑制金黄色葡萄球菌的生长。 | |||
TN1722 |
Hamamelitannin
|
Antifection | Microbiology/Virology |
Hamamelitannin 是分离自 Hamamelis virginiana 树皮的一种多酚,是群体感应抑制剂。它通过影响肽聚糖生物合成和 eDNA 释放增加金黄色葡萄球菌生物膜的抗生素敏感性。 | |||
TN3861 |
Dihydropinosylvin
山药 |
Anti-infection | Microbiology/Virology |
Dihydropinosylvin 是一种植物抗毒素,对枝孢枝孢菌、Botryodiplodia theobromae、黑曲霉和石化青霉具有抗真菌活性,对蜡状芽孢杆菌、金黄色葡萄球菌、铜绿假单胞菌和大肠杆菌也有很强的抗菌活性。双色高粱幼苗的种子和根伸长。 | |||
T6S2384 |
Poliumoside
|
Reductase | Endocrinology/Hormones; Metabolism |
Poliumoside 是从 Brandisia hancei 的茎和叶中分离出来的咖啡酰化的苯丙烷糖苷。Poliumoside 能够抑制晚期糖基化终产物的形成和大鼠晶状体醛糖还原酶,IC50分别为 19.69 和 8.47 μM。Poliumoside 具有抗炎和抗氧化特性。 | |||
TN3013 |
4,5-Dimethoxycanthin-6-one
Methylnigakinone |
P450; Antibacterial; PDE | Metabolism; Microbiology/Virology |
4,5-Dimethoxycanthin-6-one 从 Picrasma quassioides BENNET (Simaroubaceae)是一种从 Picrasma quassioides BENNET (Simaroubaceae) 中分离得到生物碱。4,5-Dimethoxycanthin-6-one 是一种有效的、非竞争性的 CYP1A2 介导的 phenacetin O-deethylation 抑制剂(IC50 : 1.7 μM, Ki : 2.6 μM),对环磷酸腺苷(cAMP)磷酸二酯酶有很强的抑制作用。4,5-Dimethoxycanthin-6-one 具有抗菌活性,对金黄色葡萄球菌及其耐药菌株有抑制作用。4,5-Dimethoxycanthin-6-one 对肿瘤细胞株 U937 和 HepG2 具有细胞毒性。 | |||
TN1203 |
2,3,8-Tri-O-methylellagic acid
2,3,8-三邻甲基鞣花酸 |
Antifection | Microbiology/Virology |
2,3,8-tri-O-Methyl ellagic acid has antimicrobial activity agaist Vibro cholera, Staphylococcus aureus, Klebsiella pneumoniae, Pseudomonas aeruginosa, Bacillus cereus, Escherichia coli. | |||
TN2760 |
2-Hydroxy-1,8-cineole
|
Antifection | Microbiology/Virology |
1. 2-endo-Hydroxy-1,8-cineole shows antimicrobial and bactericidal activities against against test bacteria (Staphylococcus aureus, Escherichia coli, and Pseudomonas fluorescens) .<BR/> | |||
T74206 |
Kalimantacin A
|
Others | Others |
Kalimantacin A是具有针对葡萄球菌(包括耐甲氧西林金黄色葡萄球菌)抗菌活性的有效抗生素。 | |||
T2S0058 |
6-Ethoxychelerythrine
乙氧基白屈菜红碱,Ethoxychelerythrin |
Antibacterial | Microbiology/Virology |
6-Ethoxychelerythrine (Ethoxychelerythrin) 具有抗菌活性,对烟曲霉和耐甲氧西林金黄色葡萄球菌 (MRSA) 表现出很强的活性。 | |||
TN2820 |
24-Methylenecycloartan-3-ol
|
Antifection | Microbiology/Virology |
24-Methylenecycloartan-3-ol and methyl caffeate show weak activity against Staphylococcus aureus and Escherichia coli. | |||
TN4851 |
Pterodondiol
|
Antifection | Microbiology/Virology |
Pterodondiol has moderate activity against bacteria including Staphylococcus aureus, Pseudomonas aeruginosa, Bacillus subtilis, Mycobacteium phlei and Bacillus circulans. | |||
TN1444 |
Bis(dihydrochelerythrinyl)amine
bis[6-(5,6-dihydrochelerythrinyl)]amine |
Antifection | Microbiology/Virology |
BIS-[6-(5,6-dihydro-chelerythrinyl)] ether shows strong activity against Aspergillus fumigatus and methicillin-resistant Staphylococcus aureus (MRSA). | |||
TN1561 |
Dehydroglaucine
|
Antifection | Microbiology/Virology |
Dehydroglaucine is an acetylcholinesterase inhibitor, it shows antimicrobial activity against Staphylococcus aureus, Mycobacterium smegmatis, Candida albicans, and Aspergillus niger. | |||
TN3216 |
(3R)-7,4’-Dihydrohomoisoflavanone
7,4'-Dihydroxyhomoisoflavanone |
Antibacterial | Microbiology/Virology |
(3R)-7,4’-Dihydrohomoisoflavanone 是一种天然化合物,对金黄色葡萄球菌和耐甲氧西林金黄色葡萄菌(MRSA)都具有强大的抗菌性能。 | |||
TN7348 |
(±)-Cannabichromenic Acid
CBCA |
Others | Others |
Cannabichromenic acid is a novel antibiotic effective against Gram-positive bacteria, including methicillin-resistant Staphylococcus aureus (MRSA). | |||
TN4579 |
Monomethylsulochrin
|
Antifection | Microbiology/Virology |
Monomethylsulochrin shows antimicrobial activity against Escherichia coli, Pseudomonas aeruginosa, Bacillus subtilis and Staphylococcus aureus. It shows moderately inhibitory effects on the human bacterial pathogen Helicobacter pylori with the MIC value of 28.9+/-0.1 microM. | |||
TN2032 |
Pachypodol
霍香黃酮醇 |
Antifection | Microbiology/Virology |
Pachypodol has antibacterial and antifungal activities against Bacillus subtilis, Staphylococcus aureus, Staphylococcus faecalis, Echerichia coli, Pseudomonas aeruginosa, Candida albicans, Candida krusei and Candida galabrata. | |||
TN5117 |
Taxiphyllin
|
Tyrosinase; Antifection | Microbiology/Virology; Proteases/Proteasome |
Taxiphyllin can inhibit tyrosinase activity in vitro significantly and is a potent tyrosinase inhibitor. Taxiphyllin displays mild antibacterial activity against Staphylococcus aureus. | |||
TN6010 |
Picrasidine S
|
||
Picrasidine S shows the potent cytotoxicity against human HeLa cervical, gastric MKN-28, and mouse melanoma B-16 cancer cells, it also shows the potent antibacterial activity against two strains of pathogenic bacteria methicillin-resistant Staphylococcus | |||
TMA0017 |
Sideroxylin
|
Antifection | Microbiology/Virology |
Sideroxylin can synergistically enhance the antimicrobial activity of the alkaloid berberine (also a constituent of H. canadensis) against Staphylococcus aureus by inhibition of the NorA multidrug resistance pump. | |||
TN4852 | Pterodontic acid | Antifection | Microbiology/Virology |
Pterodontic acid and pterodondiol showed moderate activity against bacteria including Staphylococcus aureus, Pseudomonas aeruginosa, Bacillus subtilis. | |||
T72250 |
4aα,7α,7aα-Nepetalactone
|
Others | Others |
4aα,7α,7aα-Nepetalactone 具有抗菌 (antibacterial) 活性,抑制Escherichia coli,Pseudomonas aeruginosa,Staphylococcus aureus,Salmonella typhi 和Enterococcus faecalis。 | |||
T40924 |
Tellimagrandin II
Eugeniin |
Others | Others |
Tellimagrandin II (Eugeniin) is the initial intermediate in the 4 C 1 -glucose derived series of ellagitannins. Additionally, it possesses the ability to inhibit antibiotic resistance exhibited by drug-resistant Staphylococcus aureus. | |||
TN4167 |
Grifolic acid
|
Antifection | Microbiology/Virology |
Grifolic acid is a natural carbonic anhydrase Ⅱ inhibitor(CAⅡ), it shows in-hibitory activities against CAⅡ with IC50 of 6.37 umol/L. Grifolic acid has antibacterial activity, it can inhibit the growth of Staphylococcus aureus and Staphylococcus epidermid | |||
TN3573 |
Camaric acid
|
Antifection | Microbiology/Virology |
Camaric acid shows antibacterial activity against Staphylococcus aureus and methicillin resistant S. aureus with IC50 values 8.74 and 8.09 uM, respectively, it also shows moderate antileishmanial activity and highly potent antitrypanosomal activity. Camar | |||
T80351 |
Maximin 28
|
Others | Others |
Maximin 28为源自蟾蜍大脑的抗菌肽,对金黄色葡萄球菌(Staphylococcus aureus)、大肠杆菌(Escherichia coli)及枯草芽孢杆菌(Bacillus subtilis)表现出抗菌活性,其MIC值分别为4.7、9.4、75 μg/mL。 | |||
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Cat. No. | Product Name | Species | Expression System |
---|---|---|---|
TMPH-03580 |
Zinc metalloproteinase aureolysin Protein, S. aureus, Recombinant (His & Myc)
Staphylococcus aureus neutral proteinase,a... |
Staphylococcus aureus | E. coli |
Zinc metalloproteinase aureolysin Protein, S. aureus, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 40.2 kDa and the accession number is P81177. | |||
TMPH-03561 |
lsdB Protein, S. aureus, Recombinant (His & SUMO)
Fur-regulated protein B,Iron-regulated surface determinant p... |
Staphylococcus aureus | E. coli |
Cell wall-anchored surface receptor that extracts heme from oxidized metHb to enable growth on hemoglobin as a sole iron source. Rapidly extracts heme from hemoglobin and transfers it to IsdA or IsdC, which then relays it to the membrane transporter/IsdEF for internalization. Promotes also resistance to hydrogen peroxide and killing by neutrophils. lsdB Protein, S. aureus, Recombinant (His & SUMO) is expressed in E. coli expression system with N-6xHis-SUMO tag. The predicted molecular weight is ... | |||
TMPY-06476 |
CAMP Factor Protein, Cutibacterium acnes, Recombinant (His)
|
Cutibacterium acnes | Baculovirus Insect Cells |
CAMP factor is an extracellular cytolytic protein produced by Streptococcus agalactiae. CAMP factor binds the Fc fragments of IgG and is also known as protein B, in analogy to protein A of Staphylococcus aureus. | |||
TMPH-00230 |
Cathelicidin-6 Protein, Bovine, Recombinant (His & SUMO)
CATHL6,Antibacterial peptide BMAP-27,Myeloid antibacterial p... |
Bovine | E. coli |
Exerts a potent antimicrobial activity against Gram-negative and Gram-positive bacteria, including methicillin-resistant Staphylococcus aureus, and fungi. Cathelicidin-6 Protein, Bovine, Recombinant (His & SUMO) is expressed in E. coli expression system with N-6xHis-SUMO tag. The predicted molecular weight is 16.2 kDa and the accession number is P54228. | |||
TMPH-03575 |
Sortase A Protein, S. aureus, Recombinant (His)
Surface protein sorting A,srtA,Sortase A |
Staphylococcus aureus | E. coli |
Sortase A Protein, S. aureus, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 24.9 kDa and the accession number is Q2FV99. | |||
TMPH-03525 |
Cap5A Protein, S. aureus, Recombinant (His)
Capsular polysaccharide type 5 biosynthesis protein cap5A,ca... |
Staphylococcus aureus | E. coli |
Required for the biosynthesis of type 5 capsular polysaccharide (Cap5/CP5). Might act as the chain-length regulator. Cap5A Protein, S. aureus, Recombinant (His) is expressed in E. coli expression system with N-10xHis tag. The predicted molecular weight is 26.4 kDa and the accession number is P95695. | |||
TMPH-03526 |
Cap8A Protein, S. aureus, Recombinant (His)
MAGEB2,MAGE XP-2 antigen,DAM6,MAGE-B2 antigen,Melanoma-assoc... |
Staphylococcus aureus | E. coli |
May enhance ubiquitin ligase activity of RING-type zinc finger-containing E3 ubiquitin-protein ligases. Proposed to act through recruitment and/or stabilization of the Ubl-conjugating enzyme (E2) at the E3:substrate complex. Cap8A Protein, S. aureus, Recombinant (His) is expressed in E. coli expression system with N-10xHis tag. The predicted molecular weight is 26.4 kDa and the accession number is O15479. | |||
TMPH-03543 |
Enterotoxin type C-3 Protein, S. aureus, Recombinant (His & SUMO)
SEC3,entC3,Enterotoxin type C-3 |
Staphylococcus aureus | E. coli |
Staphylococcal enterotoxin that activates the host immune system by binding as unprocessed molecules to major histocompatibility (MHC) complex class II and T-cell receptor (TCR) molecules. In turn, this ternary complex activates a large number of T-lymphocytes initiating a systemic release of proinflammatory cytokines. Causes also the intoxication staphylococcal food poisoning syndrome. Enterotoxin type C-3 Protein, S. aureus, Recombinant (His & SUMO) is expressed in E. coli expression system wi... | |||
TMPH-03546 |
Enterotoxin type G Protein, S. aureus (strain N315), Recombinant (His & SUMO)
Enterotoxin type G,entG,SEG |
Staphylococcus aureus | E. coli |
Staphylococcal enterotoxins cause the intoxication staphylococcal food poisoning syndrome. The illness is characterized by high fever, hypotension, diarrhea, shock, and in some cases death. Enterotoxin type G Protein, S. aureus (strain N315), Recombinant (His & SUMO) is expressed in E. coli expression system with N-6xHis-SUMO tag. The predicted molecular weight is 43.0 kDa and the accession number is P0A0L7. | |||
TMPH-03540 |
Enterotoxin type B Protein, S. aureus, Recombinant (GST)
entB,Enterotoxin type B,SEB |
Staphylococcus aureus | E. coli |
Staphylococcal enterotoxin that activates the host immune system by binding as unprocessed molecules to major histocompatibility (MHC) complex class II and T-cell receptor (TCR) molecules. In turn, this ternary complex activates a large number of T-lymphocytes initiating a systemic release of proinflammatory cytokines. Causes also the intoxication staphylococcal food poisoning syndrome. Enterotoxin type B Protein, S. aureus, Recombinant (GST) is expressed in E. coli expression system with N-GST ... | |||
TMPH-03518 |
ACP Protein, S. aureus, Recombinant (GST)
acpP,Fatty acid synthase acyl carrier protein,Acyl carrier p... |
Staphylococcus aureus | E. coli |
Carrier of the growing fatty acid chain in fatty acid biosynthesis. Is able to confer high methicillin resistance to S.aureus when overproduced. ACP Protein, S. aureus, Recombinant (GST) is expressed in E. coli expression system with N-GST tag. The predicted molecular weight is 35.5 kDa and the accession number is P0A001. | |||
TMPH-03553 |
HlgA Protein, S. aureus, Recombinant (His & Myc)
H-gamma-II,H-gamma-2,Gamma-hemolysin component A,hlgA |
Staphylococcus aureus | E. coli |
Toxin that seems to act by forming pores in the membrane of the cell. Has a hemolytic and a leucotoxic activity. HlgA Protein, S. aureus, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 39.4 kDa and the accession number is P0A073. | |||
TMPH-03564 |
MCAT Protein, S. aureus, Recombinant (His & SUMO)
Malonyl CoA-acyl carrier protein transacylase,fabD |
Staphylococcus aureus | E. coli |
MCAT Protein, S. aureus, Recombinant (His & SUMO) is expressed in E. coli expression system with N-6xHis-SUMO tag. The predicted molecular weight is 49.6 kDa and the accession number is Q5HGK3. | |||
TMPH-03555 |
HlgB Protein, S. aureus, Recombinant (His)
H-gamma-I,hlgB,Gamma-hemolysin component B,H-gamma-1 |
Staphylococcus aureus | P. pastoris (Yeast) |
Toxin that seems to act by forming pores in the membrane of the cell. Has a hemolytic and a leucotoxic activity. HlgB Protein, S. aureus, Recombinant (His) is expressed in yeast with N-6xHis tag. The predicted molecular weight is 36.1 kDa and the accession number is P0A075. | |||
TMPH-03559 |
Sbi Protein, S. aureus, Recombinant (Avi & His & MBP), Biotinylated
sbi,Immunoglobulin-binding protein Sbi |
Staphylococcus aureus | E. coli |
Plays a role in the inhibition of both the innate and adaptive immune responses. Possesses two N-terminal domains that bind the Fc region of IgG and two domains that form a tripartite complex with complement factors C3b and CFH. By recruiting CFH and C3b, the secreted form acts as a potent complement inhibitor of the alternative pathway-mediated lysis. Sbi Protein, S. aureus, Recombinant (Avi & His & MBP), Biotinylated is expressed in E. coli expression system with N-MBP and C-6xHis-Avi tag. The... | |||
TMPH-03545 |
Enterotoxin type E Protein, S. aureus, Recombinant (His & SUMO)
Enterotoxin type E,SEE,entE |
Staphylococcus aureus | E. coli |
Staphylococcal enterotoxin that activates the host immune system by binding as unprocessed molecules to major histocompatibility (MHC) complex class II and T-cell receptor (TCR) molecules. In turn, this ternary complex activates a large number of T-lymphocytes initiating a systemic release of proinflammatory cytokines. Causes also the intoxication staphylococcal food poisoning syndrome. | |||
TMPH-03568 |
Phospholipase C Protein, S. aureus, Recombinant (His)
hlb,Beta-hemolysin,Phospholipase C,Beta-toxin,Sphingomyelina... |
Staphylococcus aureus | P. pastoris (Yeast) |
Bacterial hemolysins are exotoxins that attack blood cell membranes and cause cell rupture. Beta-hemolysin is a phospholipase C with specific activity toward sphingomyelins. Has a high specificity for sphingomyelin, hydrolyzes lysophosphatidylcholine at a much lower rate, but has no activity towards phosphatidylcholine, phosphatidylethanolamine, or phosphatidylserine. Phospholipase C Protein, S. aureus, Recombinant (His) is expressed in yeast with N-6xHis tag. The predicted molecular weight is 3... | |||
TMPH-03557 |
HlgC Protein, S. aureus, Recombinant (His)
hlgC,Gamma-hemolysin component C |
Staphylococcus aureus | P. pastoris (Yeast) |
Toxin that seems to act by forming pores in the membrane of the cell. Has a hemolytic and a leucotoxic activity. HlgC Protein, S. aureus, Recombinant (His) is expressed in yeast with N-6xHis tag. The predicted molecular weight is 34.6 kDa and the accession number is Q7A3S2. | |||
TMPH-03578 |
SCIN Protein, S. aureus, Recombinant (His & Myc)
scn,Staphylococcal complement inhibitor |
Staphylococcus aureus | E. coli |
Involved in countering the first line of host defense mechanisms. Efficiently inhibits opsonization, phagocytosis and killing of S.aureus by human neutrophils. Acts by binding and stabilizing human C3 convertases (C4b2a and C3bBb), leading to their inactivation. The convertases are no longer able to cleave complement C3, therefore preventing further C3b deposition on the bacterial surface and phagocytosis of the bacterium. Also prevents C5a-induced neutrophil responses. SCIN Protein, S. aureus, ... | |||
TMPH-03566 |
Peptide deformylase Protein, S. aureus, Recombinant (His)
Polypeptide deformylase,def,Peptide deformylase |
Staphylococcus aureus | P. pastoris (Yeast) |
Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions. Peptide deformylase Protein, S. aureus, Recombinant (His) is expressed in yeast with N-6xHis tag. The predicted molecular weight is 22.6 kDa and the accession number is P68826. | |||
TMPH-03572 |
SplB Protein, S. aureus, Recombinant (His & Myc)
splB,Serine protease SplB |
Staphylococcus aureus | E. coli |
Serine protease that cleaves specifically after the sequence Trp-Glu-Leu-Gln. SplB Protein, S. aureus, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 29.8 kDa and the accession number is A7X3Q8. | |||
TMPH-03516 |
NPTase Protein, S. aureus, Recombinant (His & SUMO)
30 kDa neutral phosphatase |
Staphylococcus aureus | E. coli |
Highly cationic enzyme that can bind human or rat immunoglobulins as well as serum albumin, and could therefore be involved in post-infectious sequelae. NPTase Protein, S. aureus, Recombinant (His & SUMO) is expressed in E. coli expression system with N-6xHis-SUMO tag. The predicted molecular weight is 19.7 kDa and the accession number is P21222. | |||
TMPH-03550 |
EsxA Protein, S. aureus, Recombinant (His & SUMO)
esxA,Type VII secretion system extracellular protein A |
Staphylococcus aureus | E. coli |
Virulence factor that is important for the establishment of infection in the host. EsxA is required for EsxB synthesis as well as secretion. Modulates host cell apoptotic pathways and mediates together with EsxB the release of S.aureus from the host cell. By acting on apoptosis, plays a role in the modulation of dendritic cell-mediated immunity. EsxA Protein, S. aureus, Recombinant (His & SUMO) is expressed in E. coli expression system with N-6xHis-SUMO tag. The predicted molecular weight is 27.... | |||
TMPH-03541 |
Enterotoxin type C-2 Protein, S. aureus, Recombinant (His & SUMO)
Enterotoxin type C-2,SEC2,entC2 |
Staphylococcus aureus | E. coli |
Staphylococcal enterotoxin that activates the host immune system by binding as unprocessed molecules to major histocompatibility (MHC) complex class II and T-cell receptor (TCR) molecules. In turn, this ternary complex activates a large number of T-lymphocytes initiating a systemic release of proinflammatory cytokines. Causes also the intoxication staphylococcal food poisoning syndrome. Enterotoxin type C-2 Protein, S. aureus, Recombinant (His & SUMO) is expressed in E. coli expression system wi... | |||
TMPH-03544 |
Enterotoxin type D Protein, S. aureus, Recombinant (His & SUMO)
entD,SED,Enterotoxin type D |
Staphylococcus aureus | E. coli |
Staphylococcal enterotoxin that activates the host immune system by binding as unprocessed molecules to major histocompatibility (MHC) complex class II and T-cell receptor (TCR) molecules. In turn, this ternary complex activates a large number of T-lymphocytes initiating a systemic release of proinflammatory cytokines. In addition, induces B-cell proliferation and differentiation in the presence of T-cells. Causes also the intoxication staphylococcal food poisoning syndrome. Enterotoxin type D P... | |||
TMPH-03532 |
ClfB Protein, S. aureus (strain MRSA252), Recombinant (His & SUMO)
Clumping factor B,clfB,Fibrinogen receptor B,Fibrinogen-bind... |
Staphylococcus aureus | E. coli |
Cell surface-associated protein implicated in virulence by promoting bacterial attachment to both alpha- and beta-chains of human fibrinogen and inducing the formation of bacterial clumps. ClfB Protein, S. aureus (strain MRSA252), Recombinant (His & SUMO) is expressed in E. coli expression system with N-6xHis-SUMO tag. The predicted molecular weight is 69.8 kDa and the accession number is Q6GDH2. | |||
TMPH-03523 |
Alpha-hemolysin Protein, S. aureus, Recombinant (His & SUMO)
Alpha-HL,Alpha-toxin |
Staphylococcus aureus | E. coli |
Alpha-toxin binds to the membrane of eukaryotic cells resulting in the release of low-molecular weight molecules and leading to an eventual osmotic lysis. Inhibits host neutrophil chemotaxis to the lesion region (Probable). Heptamer oligomerization and pore formation is required for lytic activity. | |||
TMPH-03519 |
ACP Protein, S. aureus, Recombinant (His)
Cytosolic-activating factor,Fatty acid synthase acyl carrier... |
Staphylococcus aureus | P. pastoris (Yeast) |
Carrier of the growing fatty acid chain in fatty acid biosynthesis. Is able to confer high methicillin resistance to S.aureus when overproduced. ACP Protein, S. aureus, Recombinant (His) is expressed in yeast with N-6xHis tag. The predicted molecular weight is 10.5 kDa and the accession number is P0A001. | |||
TMPH-03530 |
ClfA Protein, S. aureus (strain COL), Recombinant (E. coli, His)
clfA,Fibrinogen-binding protein A,Fibrinogen receptor A,Clum... |
Staphylococcus aureus | E. coli |
Cell surface-associated protein implicated in virulence. Promotes bacterial attachment exclusively to the gamma-chain of human fibrinogen. Induces formation of bacterial clumps. ClfA Protein, S. aureus (strain COL), Recombinant (E. coli, His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 40.0 kDa and the accession number is Q5HHM8. | |||
TMPH-03527 |
FtsZ Protein, S. aureus, Recombinant (His)
ftsZ,Cell division protein FtsZ |
Staphylococcus aureus | E. coli |
Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity. FtsZ Protein, S. aureus, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The ... | |||
TMPH-03556 |
HlgC Protein, S. aureus, Recombinant (E. coli, His)
hlgC,Gamma-hemolysin component C |
Staphylococcus aureus | E. coli |
Toxin that seems to act by forming pores in the membrane of the cell. Has a hemolytic and a leucotoxic activity. HlgC Protein, S. aureus, Recombinant (E. coli, His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 36.6 kDa and the accession number is Q7A3S2. | |||
TMPH-03563 |
MCAT Protein, S. aureus, Recombinant (His)
fabD,Malonyl CoA-acyl carrier protein transacylase |
Staphylococcus aureus | P. pastoris (Yeast) |
MCAT Protein, S. aureus, Recombinant (His) is expressed in yeast with N-6xHis tag. The predicted molecular weight is 35.6 kDa and the accession number is Q5HGK3. | |||
TMPH-03577 |
Staphopain B Protein, S. aureus, Recombinant (GST)
Staphopain B,sspB,Staphylopain B,Staphylococcal cysteine pro... |
Staphylococcus aureus | E. coli |
Cysteine protease that plays an important role in the inhibition of host innate immune response. Degrades host elastin, fibrogen, fibronectin and kininogen. Blocks phagocytosis of opsonised S. aureus by neutrophils and monocytes by inducing their death in a proteolytic activity-dependent manner. Decreases surface expression of the 'don't eat me' signal CD31 on neutrophils. Cleaves host galectin-3/LGALS3, thereby inhibiting the neutrophil-activating ability of the lectin. Staphopain B Protein, S.... | |||
TMPH-03542 |
Enterotoxin type C-2 Protein, S. aureus, Recombinant
Enterotoxin type C-2,entC2,SEC2 |
Staphylococcus aureus | E. coli |
Staphylococcal enterotoxin that activates the host immune system by binding as unprocessed molecules to major histocompatibility (MHC) complex class II and T-cell receptor (TCR) molecules. In turn, this ternary complex activates a large number of T-lymphocytes initiating a systemic release of proinflammatory cytokines. Causes also the intoxication staphylococcal food poisoning syndrome. Enterotoxin type C-2 Protein, S. aureus, Recombinant is expressed in E. coli expression system. The predicted ... | |||
TMPH-03537 |
Enterotoxin type A Protein, S. aureus, Recombinant (His)
Enterotoxin type A,SEA,entA |
Staphylococcus aureus | E. coli |
Enterotoxin type A Protein, S. aureus, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 31.1 kDa and the accession number is P0A0L2. | |||
TMPH-03547 |
Enterotoxin type G Protein, S. aureus (strain Mu50/ATCC 700699), Recombinant (His & SUMO)
SEG,Enterotoxin type G,entG |
Staphylococcus aureus | E. coli |
Staphylococcal enterotoxins cause the intoxication staphylococcal food poisoning syndrome. The illness is characterized by high fever, hypotension, diarrhea, shock, and in some cases death. Enterotoxin type G Protein, S. aureus (strain Mu50/ATCC 700699), Recombinant (His & SUMO) is expressed in E. coli expression system with N-6xHis-SUMO tag. The predicted molecular weight is 43.0 kDa and the accession number is P0A0L6. | |||
TMPH-03538 |
Enterotoxin type A Protein, S. aureus, Recombinant (His & Myc)
Enterotoxin type A,SEA,entA |
Staphylococcus aureus | Baculovirus Insect Cells |
Enterotoxin type A Protein, S. aureus, Recombinant (His & Myc) is expressed in Baculovirus insect cells with N-10xHis and C-Myc tag. The predicted molecular weight is 31.0 kDa and the accession number is P0A0L2. | |||
TMPH-03539 |
Enterotoxin type B Protein, S. aureus, Recombinant (His)
Enterotoxin type B,SEB,entB |
Staphylococcus aureus | P. pastoris (Yeast) |
Staphylococcal enterotoxin that activates the host immune system by binding as unprocessed molecules to major histocompatibility (MHC) complex class II and T-cell receptor (TCR) molecules. In turn, this ternary complex activates a large number of T-lymphocytes initiating a systemic release of proinflammatory cytokines. Causes also the intoxication staphylococcal food poisoning syndrome. | |||
TMPH-03514 |
ClfA Protein, S. aureus (strain MSSA476), Recombinant (His & SUMO)
Fibrinogen receptor A,Fibrinogen-binding protein A,clfA,Clum... |
Staphylococcus aureus | E. coli |
Cell surface-associated protein implicated in virulence. Promotes bacterial attachment exclusively to the gamma-chain of human fibrinogen. Induces formation of bacterial clumps. ClfA Protein, S. aureus (strain MSSA476), Recombinant (His & SUMO) is expressed in E. coli expression system with N-6xHis-SUMO tag. The predicted molecular weight is 52.1 kDa and the accession number is Q6GB45. | |||
TMPH-03522 |
Alpha-hemolysin Protein, S. aureus, Recombinant (His)
Alpha-toxin,Alpha-HL |
Staphylococcus aureus | P. pastoris (Yeast) |
Alpha-toxin binds to the membrane of eukaryotic cells resulting in the release of low-molecular weight molecules and leading to an eventual osmotic lysis. Inhibits host neutrophil chemotaxis to the lesion region (Probable). Heptamer oligomerization and pore formation is required for lytic activity. | |||
TMPH-03571 |
WalK Protein, S. aureus, Recombinant (His & Myc)
walK,Sensor protein kinase WalK |
Staphylococcus aureus | E. coli |
WalK Protein, S. aureus, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 29.3 kDa and the accession number is A6QD58. | |||
TMPH-03576 |
Staphopain A Protein, S. aureus, Recombinant (His & Myc)
Staphopain A,Staphylopain A,sspP,Staphylococcal cysteine pro... |
Staphylococcus aureus | E. coli |
Staphopain A Protein, S. aureus, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 27.4 kDa and the accession number is P81297. | |||
TMPH-03554 |
HlgB Protein, S. aureus, Recombinant (E. coli, His)
H-gamma-1,Gamma-hemolysin component B,H-gamma-I,hlgB |
Staphylococcus aureus | E. coli |
Toxin that seems to act by forming pores in the membrane of the cell. Has a hemolytic and a leucotoxic activity. HlgB Protein, S. aureus, Recombinant (E. coli, His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 38.1 kDa and the accession number is P0A075. | |||
TMPH-03558 |
LytM Protein, S. aureus, Recombinant (His)
Autolysin LytM,Glycyl-glycine endopeptidase LytM,lytM |
Staphylococcus aureus | E. coli |
Peptidoglycan hydrolase (autolysin) specifically acting on polyglycine interpeptide bridges of the cell wall peptidoglycan. LytM Protein, S. aureus, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 35.9 kDa and the accession number is O33599. | |||
TMPH-03521 |
MecA Protein, S. aureus, Recombinant (His & SUMO)
Adapter protein MecA,mecA |
Staphylococcus aureus | E. coli |
Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis. MecA Protein, S. aureus, Recombinant (His & SUMO) is expressed in E. coli expression system with N-6xHis-SUMO tag. The predicted molecular weight is 44.3 kDa and the accession number is P60186. | |||
TMPH-03574 |
SdrE Protein, S. aureus, Recombinant (His)
sdrE,Serine-aspartate repeat-containing protein E |
Staphylococcus aureus | E. coli |
Cell surface-associated calcium-binding protein which plays an important role in adhesion and pathogenesis. Contributes to the resistance to killing by innate immune components in blood and thus attenuates bacterial clearance by interacting with host complement factor H/CFAH and modulating its activity. Inhibits also bacterial opsonization and killing by interacting with host complement regulator C4BPA and thus inhibiting classical complement pathway activation. SdrE Protein, S. aureus, Recombin... | |||
TMPH-03552 |
Exfoliative toxin B Protein, S. aureus, Recombinant (His & Myc)
etb,Epidermolytic toxin B,Exfoliative toxin B |
Staphylococcus aureus | E. coli |
Has serine protease-like properties and binds to the skin protein profilaggrin. Cleaves substrates after acidic residues. Exfoliative toxins cause impetigous diseases commonly referred as staphylococcal scalded skin syndrome (SSSS). Exfoliative toxin B Protein, S. aureus, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 34.8 kDa and the accession number is P09332. | |||
TMPH-03524 |
KAS III Protein, S. aureus, Recombinant (His & Myc)
3-oxoacyl-[acyl-carrier-protein] synthase 3,3-oxoacyl-[acyl-... |
Staphylococcus aureus | E. coli |
Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids. KAS III Protein, S. au... | |||
TMPH-03517 |
Ribosomal protein uS5 Protein, S. aureus, Recombinant (His & Myc)
30S ribosomal protein S5,rpsE,Small ribosomal subunit protei... |
Staphylococcus aureus | E. coli |
With S4 and S12 plays an important role in translational accuracy.; Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body. Ribosomal protein uS5 Protein, S. aureus, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 24.8 kDa and the accession number is A6QJ75. | |||
TMPH-03570 |
IsaA Protein, S. aureus, Recombinant (His & Myc)
Probable transglycosylase IsaA,Immunodominant staphylococcal... |
Staphylococcus aureus | E. coli |
Is able to cleave peptidoglycan. IsaA Protein, S. aureus, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 28.8 kDa and the accession number is P60157. | |||
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