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Cat. No. | Product Name | Target | Signaling Pathways |
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T35781 |
Sphinganine (d20:0)
Sphinganine (d20:0) |
Others | Others |
Sphinganine (d20:0) is a natural isomer of dihydro-D-erythro-sphinganine (sphinganine (d18:0); that is a precursor of ceramide and sphingosine as well as a substrate for sphingosine kinases, which generate sphingosine-1-phosphate (d18:1) . In S. cerevisiae, the amount of sphinganine (d20:0) increases 10.8-fold in response to heat stress, indicating it is involved in heat stress adaptation. Sphinganine levels increase significantly in response to certain mycotoxins, including fumonisins as well ... | |||
T36437 |
Sphinganine (d17:0)
Sphinganine (d17:0) |
Others | Others |
Sphinganine is a synthetic bioactive sphingolipid that inhibits the growth of C. glabrata and C. albicans with a minimum fungicidal concentration (MFC) value of 0.5 μg/ml for both. More commonly, sphinganine is used as an internal standard in the analysis of sphingoid compounds by chromatographic or spectrometric methods. | |||
T39401 |
Sphinganine 1-phosphate
D-erythro-Dihydrosphingosine 1-phosphate,Sphinganine 1-phosphate |
Others | Others |
Sphinganine 1-phosphate, also known as D-erythro-Dihydrosphingosine 1-phosphate, is a polar sphingolipid metabolite. It plays a crucial role in regulating various cellular processes including cell migration, differentiation, survival, and complex physiological processes. | |||
T37952 |
Sphinganine-1-phosphate (d17:0)
Sphinganine-1-phosphate (d17:0) |
Others | Others |
Sphinganine-1-phosphate (d17:0) is a sphingolipid analog of sphinganine-1-phosphate (d18:0) and sphingosine-1-phosphate (d18:1) that has a 17-carbon base. Sphinganine-1-phosphate (d17:0) levels are lower in surgical and cadaver trabecular meshwork samples isolated from patients with primary open angle glaucoma compared with control samples. | |||
T36987 |
N,N-dimethyl Sphinganine (d18:0)
N,N-dimethyl Sphinganine (d18:0) |
Others | Others |
N,N-dimethyl Sphinganine (d18:0) is a sphingolipid that increases during development ofL. donovanipromastigotes.1 1.Silva, A.M., Cordeiro-da-Silva, A., and Coombs, G.H.Metabolic variation during development in culture of Leishmania donovani promastigotesPLoS Negl. Trop. Dis.5(12)e1451(2011) | |||
T37010 |
D-threo Sphinganine (d18:0)
D-threo Sphinganine (d18:0) |
Others | Others |
D-threo Sphinganine (d18:0) is a synthetic bioactive sphingolipid and stereoisomer of sphinganine (d18:0) and L-erythro sphinganine (d18:0) . It induces autophagy in HCT116 cells when used at a concentration of 12 μM. D-threo Sphinganine (d18:0) is metabolized via sphinganine N-acyltransferase and sphinganine kinase in vivo in rat liver. | |||
T36613 |
DL-erythro/threo Sphinganine (d16:0)
DL-erythro/threo Sphinganine (d16:0) |
Others | Others |
DL-erythro/threo Sphinganine (d16:0) is a sphingolipid that is decreased in rats following long-term, low-dose administration of dimethoate and is used as a biomarker for dimethoate exposure. It has been found in the fermentation broth of Bacterium SRCnm, which has antimicrobial and antioxidant activities. This product is a mixture of sphinganine (d16:0), L-erythro sphinganine (d16:0), D-threo sphinganine (d16:0), and L-threo sphinganine (d16:0). | |||
T85174 |
3-keto Sphinganine (d12:0) hydrochloride
3-keto Sphinganine (d12:0),3-keto Dihydrosphingosine (d12:0) |
Others | Others |
3-Keto Sphinganine (d12:0) is a short-chain analog of 3-keto sphinganine (d18:0), which typically possesses a C18 chain length. The latter is a lyso-sphingolipid synthesized through the condensation of L-serine and palmitoyl-CoA mediated by the enzyme serine palmitoyl transferase (SPT). A deficiency in Vitamin K deactivates SPT, leading to a reduced synthesis of 3-keto sphinganine among other sphingolipids. [Matreya, LLC. Catalog No. 1893] | |||
T82794 |
C6-NBD Sphinganine
|
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C6-NBD Sphinganine, 一种荧光染料, 用于标记鞘氨酸类似物的脂肪酸。 | |||
T84940 |
Sphinganine (d16:0 branched)
iso-C17:0 |
Others | Others |
Sphinganine (d16:0 branched), an aniso-branched sphingolipid, is identified as a constituent of ceramide-containing phospholipids in bacteria. | |||
T37454 |
C16 dihydro Ceramide (d18:0/16:0)
N-Palmitoyl Sphinganine,Cer(d18:0/16:0),N-hexadecanoyl-D-erythro-Dihydrosphingosine,C16 dihydroceramide,Ceramide (d18:0/16:0) |
Others | Others |
C16 dihydro Ceramide (d18:0/16:0) (Cer(d18:0/16:0)) 是合成神经酰胺的前体,诱导核周区域自噬,可用于研究细胞膜的稳定性和神经系统疾病。 | |||
T85070 |
C24:1 dihydro 1-Deoxyceramide (m18:0/24:1)
Cer(m18:0/24:1),C24:1 deoxyDHCeramide,C24:1 dihydro Ceramide (m18:0/24:1),C24:1deoxyDHCer,C24:1 deoxy Dihydroceramide,N-tetracosenoyl-1-deoxy-Sphinganine |
Others | Others |
T84383 |
C2 dihydro Ceramide (d18:0/2:0)
Cer(d18:0/2:0),N-acetyl-D-erythro-Sphinganine,N-acetyl-dihydro-Sphingosine,Ceramide (d18:0/2:0),N-acetyl-D-erythro-dihydro-Sphingosine |
Others | Others |
T36833 |
A6770
|
Others | Others |
A6770 is an inhibitor of sphingosine-1-phosphate (S1P) lyase.1It induces accumulation of [3H]sphinganine-1-phosphate ([3H]dhS1P), an S1P lyase substrate, in IT-79MTNC3 cells that endogenously express high levels of S1P lyase (EC50= <0.01 μM), an effect that is reduced in the presence of vitamin B6(EC50= <100 μM). 1.Ohtoyo, M., Tamura, M., Machinaga, N., et al.Scintillation proximity assay to detect the changes in cellular dihydrosphingosine 1-phosphate levelsLipids51(10)1207-1216(2016) |
Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T13632 |
D-Erythro-dihydrosphingosine
Dihydrosphingosine,Octadecasphinganine,D-赤式-C 18 - 二氢-D-神经鞘氨醇,C18-Dihydrosphingosine,D-erythro-Sphinganine |
Phospholipase; Endogenous Metabolite | Metabolism |
D-Erythro-dihydrosphingosine (C18-Dihydrosphingosine) 可抑制花生四烯酸的释放和cPLA2α活性。 |